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Witvrouw M

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Publications:

Title Authors Year Journal
Synthesis and anti-HIV evaluation of novel 1,3-disubstituted thieno[3,2-c][1,2,6]thiadiazin-4(3H)-one 2,2-dioxides(TTDDs). Witvrouw M 2008 Bioorganic & medicinal chemistry
Synthesis of novel derivatives of 4-amino-3-(2-furyl)-5-mercapto-1,2,4-triazole as potential HIV-1 NNRTIs. Witvrouw M 2007 Molecules (Basel, Switzerland)
Antiviral activity of 3-(3,5-dimethylbenzyl)uracil derivatives against HIV-1 and HCMV. Witvrouw M 2007 Nucleosides, nucleotides & nucleic acids
Synthesis and anti-HIV-1 and anti-HCMV activity of 1-substituted 3-(3,5-dimethylbenzyl)uracil derivatives. Witvrouw M 2006 Chemical & pharmaceutical bulletin
Resistance of human immunodeficiency virus type 1 to the high-mannose binding agents cyanovirin N and concanavalin A. Witvrouw M 2005 Journal of virology
Novel inhibitors of HIV-1 integration. Witvrouw M 2004 Current drug metabolism
Potent and selective inhibition of HIV and SIV by prostratin interacting with viral entry. Witvrouw M 2003 Antiviral chemistry & chemotherapy
Synthesis and antiviral activity of 1,3-disubstituted uracils against HIV-1 and HCMV. Witvrouw M 2003 Antiviral chemistry & chemotherapy
N-aminoimidazole derivatives inhibiting retroviral replication via a yet unidentified mode of action. Witvrouw M 2003 Journal of medicinal chemistry
In search of authentic inhibitors of HIV-1 integration. Witvrouw M 2002 Antiviral chemistry & chemotherapy
New class of HIV integrase inhibitors that block viral replication in cell culture. Witvrouw M 2002 Current biology : CB
Inhibition of human immunodeficiency virus type 1 integration by diketo derivatives. Witvrouw M 2002 Antimicrobial agents and chemotherapy
Anti-HIV-1 activity of benzothiadiazine dioxide. Witvrouw M 2001 Antiviral chemistry & chemotherapy
Synthesis, biological activity, pharmacokinetic properties and molecular modelling studies of novel 1H,3H-oxazolo[3,4-a]benzimidazoles: non-nucleoside HIV-1 reverse transcriptase inhibitors. Witvrouw M 2001 Antiviral chemistry & chemotherapy
Synthesis and anti-HIV activity of cosalane analogues incorporating nitrogen in the linker chain. Witvrouw M 2000 Bioorganic & medicinal chemistry
In vitro evaluation of the effect of temporary removal of HIV drug pressure. Witvrouw M 2000 Antiviral research
Evaluating Clinical Isolates for Their Phenotypic and Genotypic Resistance Against Anti-HIV Drugs. Witvrouw M 2000 Methods in molecular medicine
Presence of 2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5"-(4"-amino-1",2"-oxath iole-2",2"-dioxide) (TSAO)-resistant virus strains in TSAO-inexperienced HIV patients. Witvrouw M 2000 AIDS research and human retroviruses
Polyanionic (i.e., polysulfonate) dendrimers can inhibit the replication of human immunodeficiency virus by interfering with both virus adsorption and later steps (reverse transcriptase/integrase) in the virus replicative cycle. Witvrouw M 2000 Molecular pharmacology
Prevalence and characteristics of multinucleoside-resistant human immunodeficiency virus type 1 among European patients receiving combinations of nucleoside analogues. Witvrouw M 2000 Antimicrobial agents and chemotherapy
Activity of non-nucleoside reverse transcriptase inhibitors against HIV-2 and SIV. Witvrouw M 1999 AIDS (London, England)
Inhibition of human immunodeficiency virus type (HIV-1) replication by some diversely functionalized spirocyclopropyl derivatives. Witvrouw M 1999 Archiv der Pharmazie
Synthesis and anti-HIV activity of 1,1,3-trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazines (TTDs): a new family of HIV-1 specific non-nucleoside reverse transcriptase inhibitors. Witvrouw M 1999 Bioorganic & medicinal chemistry
Lamivudine resistance of HIV type 1 does not delay development of resistance to nonnucleoside HIV type 1-specific reverse transcriptase inhibitors as compared with wild-type HIV type 1. Witvrouw M 1998 AIDS research and human retroviruses
1,1,3-Trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazine (TTD) derivatives: a new class of nonnucleoside human immunodeficiency virus type 1 (HIV-1) reverse transcriptase inhibitors with anti-HIV-1 activity. Witvrouw M 1998 Antimicrobial agents and chemotherapy
Novel 1,1,3-trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazine derivatives as non-nucleoside reverse transcriptase inhibitors that inhibit human immunodeficiency virus type 1 replication. Witvrouw M 1998 Journal of medicinal chemistry
Multiple dideoxynucleoside analogue-resistant (MddNR) HIV-1 strains isolated from patients from different European countries. Witvrouw M 1998 AIDS (London, England)
Sulfated polysaccharides extracted from sea algae as potential antiviral drugs. Witvrouw M 1997 General pharmacology
SRR-SB3, a disulfide-containing macrolide that inhibits a late stage of the replicative cycle of human immunodeficiency virus. Witvrouw M 1997 Antimicrobial agents and chemotherapy
Antiviral activity of the bicyclam derivative JM3100 against drug-resistant strains of human immunodeficiency virus type 1. Witvrouw M 1996 Antiviral research
New arylpyrido-diazepine and -thiodiazepine derivatives are potent and highly selective HIV-1 inhibitors targeted at the reverse transcriptase. Witvrouw M 1996 Antiviral research
Highly favorable antiviral activity and resistance profile of the novel thiocarboxanilide pentenyloxy ether derivatives UC-781 and UC-82 as inhibitors of human immunodeficiency virus type 1 replication. Witvrouw M 1996 Molecular pharmacology

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