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Polymerase: T4 A89TD363N, Property: Nucleotide Substitution Rate

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Polymerase Reference Property Result Context
T4 A89TD363N 2-Aminopurine-induced mutagenesis in T4 bacteriophage: a model relating mutation frequency to 2-aminopurine incorporation in DNA. Nucleotide Substitution Rate 100 Mutation frequency (relative to WT) Technique: T4 rII 199oc reversion assay (Spontaneous)
T4 A89TD363N 2-Aminopurine-induced mutagenesis in T4 bacteriophage: a model relating mutation frequency to 2-aminopurine incorporation in DNA. Nucleotide Substitution Rate 5 Mutation frequency (relative to WT) Technique: T4 rII 199oc reversion assay (AP-induced)
T4 A89TD363N 2-Aminopurine-induced mutagenesis in T4 bacteriophage: a model relating mutation frequency to 2-aminopurine incorporation in DNA. Nucleotide Substitution Rate 3.8 Mutation frequency (relative to WT) Technique: T4 rII 199oc reversion assay (dCMP-AP mismatch)
T4 A89TD363N DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. Nucleotide Substitution Rate 74 Mutation frequency (relative to WT) Technique: T4 rII 199oc reversion assay
T4 A89TD363N DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. Nucleotide Substitution Rate 36 Mutation frequency (relative to WT) Technique: ac forward mutational assay
T4 A89TD363N Locations of amino acid substitutions in bacteriophage T4 tsL56 DNA polymerase predict an N-terminal exonuclease domain. Nucleotide Substitution Rate 20 Mutation frequency (relative to WT) Technique: ac forward mutational assay
T4 A89TD363N Studies on the biochemical basis of mutation VI. Selection and characterization of a new bacteriophage T4 mutator DNA polymerase. Nucleotide Substitution Rate 80 Mutation frequency (relative to WT) Technique: T4 rII 199oc reversion assay
T4 A89TD363N Isolation of bacteriophage T4 DNA polymerase mutator mutants. Nucleotide Substitution Rate 90 Mutation frequency (relative to WT) Technique: T4 rII P7oc reversion assay (AT->GC (P7oc->P7am))
T4 A89TD363N Isolation of bacteriophage T4 DNA polymerase mutator mutants. Nucleotide Substitution Rate 570 Mutation frequency (relative to WT) Technique: T4 rII P7oc reversion assay (AT->TA(CG) (P7oc->rII+))
T4 A89TD363N Isolation of bacteriophage T4 DNA polymerase mutator mutants. Nucleotide Substitution Rate 1900 Mutation frequency (relative to WT) Technique: T4 rII P7am reversion assay (GC->TA(CG) (P7am->rII+))
T4 A89TD363N Studies on the biochemical basis of mutation. IV. Effect of amino acid substitution on the enzymatic and biological properties of bacteriophage T4 DNA polymerase. Nucleotide Substitution Rate 68 Mutation frequency (relative to WT) Technique: T4 rII 199oc reversion assay (Host: B40(sup+1))
T4 A89TD363N Studies on the biochemical basis of mutation. IV. Effect of amino acid substitution on the enzymatic and biological properties of bacteriophage T4 DNA polymerase. Nucleotide Substitution Rate 100 Mutation frequency (relative to WT) Technique: T4 rII 199oc reversion assay (Host: B40(sup+2))
T4 A89TD363N Studies on the biochemical basis of mutation. IV. Effect of amino acid substitution on the enzymatic and biological properties of bacteriophage T4 DNA polymerase. Nucleotide Substitution Rate 62 Mutation frequency (relative to WT) Technique: T4 rII 199oc reversion assay (Host: B40(sup+3))
T4 A89TD363N Studies on the biochemical basis of mutation. IV. Effect of amino acid substitution on the enzymatic and biological properties of bacteriophage T4 DNA polymerase. Nucleotide Substitution Rate 254 Mutation frequency (relative to WT) Technique: T4 rII 199oc reversion assay (Host: B40(sup+2))

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.