Replication of O6-methylguanine-containing DNA by repair and replicative DNA polymerases.

Abstract:

The biological consequences of O6-methylguanine (m6G) in DNA are well ...

Polymerases:

Topics:

Kinetic Parameters, Nucleotide Analogs / Template Lesions, Accessory Proteins/Complexes, Nucleotide Incorporation

Status:

new topics/pols set partial results complete validated

Results:

Polymerase Reference Property Result Context
T4 D112AE114A Replication of O6-methylguanine-containing DNA by repair and replicative DNA polymerases. Vmax 0.01 /second Reaction: Nucleotide incorporation; Substrate: dNTPs
T4 D112AE114A Replication of O6-methylguanine-containing DNA by repair and replicative DNA polymerases. Vmax 0.04 /second Reaction: Nucleotide incorporation; Substrate: dNTPs
T4 D112AE114A Replication of O6-methylguanine-containing DNA by repair and replicative DNA polymerases. Vmax 0.004 /second Reaction: Nucleotide incorporation; Substrate: dCTP
T4 D112AE114A Replication of O6-methylguanine-containing DNA by repair and replicative DNA polymerases. Vmax 0.03 /second Substrate: dCTP
T4 D112AE114A Replication of O6-methylguanine-containing DNA by repair and replicative DNA polymerases. Vmax 0.0003 /second Reaction: Nucleotide incorporation; Substrate: dTTP
T4 D112AE114A Replication of O6-methylguanine-containing DNA by repair and replicative DNA polymerases. Vmax 0.01 /second Reaction: Nucleotide incorporation; Substrate: dTTP
T4 D112AE114A Replication of O6-methylguanine-containing DNA by repair and replicative DNA polymerases. Vmax 0.005 /second Reaction: Nucleotide incorporation; Substrate: dTTP
T4 D112AE114A Replication of O6-methylguanine-containing DNA by repair and replicative DNA polymerases. Vmax 0.04 /second Reaction: Nucleotide incorporation; Substrate: dTTP

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