T4 D112AE114A

From bacteriophage T4 (aliases:T4 exo-)
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Welcome to the Polymerase Page

This page presents all the information in Polbase for T4 D112AE114A.

Mutants:

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Structures/Sequence:

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References:

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Results:

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Mutant of: T4 (D112A,E114A)

T4 D112AE114A is a family B enzyme from bacteriophage T4.

Selected Properties for T4 D112AE114A:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
No (1) no data no data 3.0e+02-3.0e+02 Mutation frequency (relative to WT) (2) no data
Year Authors Title Results by property
2010 Linda J Reha-Krantz DNA polymerase proofreading: Multiple...
2008 Linda J Reha-Krantz Recent patents of gene sequences rela...
2007 Elizabeth Fidalgo da Silva, Linda J Reha-Krantz DNA polymerase proofreading: active s... 3-5' exo,All properties
2006 Chithra Hariharan, Linda B Bloom, Sandra A Helquist, Eric T Kool, Linda J Reha-Krantz Dynamics of nucleotide incorporation:... Kd,All properties
2006 Matthew Hogg, Wendy Cooper, Linda J Reha-Krantz, Susan S Wallace Kinetics of error generation in homol... Kd,kcat,All properties
2005 Chithra Hariharan, Linda J Reha-Krantz Using 2-aminopurine fluorescence to d...
2003 Laura Tsujikawa, Michael Weinfield, Linda J Reha-Krantz Differences in replication of a DNA t...
2002 Elizabeth Fidalgo da Silva, Subhrangsu S Mandal, Linda J Reha-Krantz Using 2-aminopurine fluorescence to m... Kd,All properties
2002 Subhrangsu S Mandal, Elizabeth Fidalgo da Silva, Linda J Reha-Krantz Using 2-aminopurine fluorescence to d... Kd,All properties
2000 E F da Silva, Linda J Reha-Krantz Dinucleotide repeat expansion catalyz...
1999 E Elisseeva, Subhrangsu S Mandal, Linda J Reha-Krantz Mutational and pH studies of the 3' -...
1998 R P Baker, Linda J Reha-Krantz Identification of a transient excisio... Nucleotide Substitution Rate,All properties
1998 P Keohavong, R Shukla, A Melacrinos, B W Day, Linda J Reha-Krantz Effects of bulky polycyclic aromatic ...
1998 J M Beechem, M R Otto, Linda B Bloom, R Eritja, Linda J Reha-Krantz, Myron F Goodman Exonuclease-polymerase active site pa...
1998 Zafer Hatahet, Mian Zhou, Linda J Reha-Krantz, S W Morrical, Susan S Wallace In search of a mutational hotspot. KM,All properties
1998 Linda J Reha-Krantz, L A Marquez, E Elisseeva, R P Baker, Linda B Bloom, H B Dunford, Myron F Goodman The proofreading pathway of bacteriop...
1996 Linda J Reha-Krantz, R L Nonay, R S Day, Samuel H Wilson Replication of O6-methylguanine-conta... Vmax,All properties
1993 Linda J Reha-Krantz, R L Nonay Genetic and biochemical studies of ba... Nucleotide Substitution Rate,All properties

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