Human Pol delta

From H. sapiens (aliases:Human pol δ) (genes: POLD1)
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Welcome to the Polymerase Page

This page presents all the information in Polbase for Human Pol delta.

Mutants:

At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.

Structures/Sequence:

If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.

References:

All references that refer to this Polymerase are listed with their topics and paper's title in the References table.

Results:

All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

Human Pol delta is a family B enzyme from H. sapiens.

Selected Properties for Human Pol delta:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
Yes (4) No (3) no data 1.0e-05 errors/bp (1) no data
Year Authors Title Results by property
2013 Jessica L Sneeden, Sara M Grossi, Inger Tappin, Jerard Hurwitz, Wolf-Dietrich Heyer Sneeden JL2013
2013 JD Lormand, N Buncher, CT Murphy, P Kaur, Marietta Y W T Lee, P Burgers, Hongyun Wang, Thomas A Kunkel, Patricia L Opresko Lormand JD2013
2013 Bo Cao, Zihan Zhang, Yuqin Zhang, Jinming Li, Gang Liang, Jianghong Ling Cao B2013
2013 Sufang Zhang, Hong Zhao, Zbiegniew Darzynkiewicz, Pengbo Zhou, Zhongtao Zhang, Ernest Y C Lee, Marietta Y W T Lee Zhang S2013
2013 Szu Hua Sharon Lin, Xiaoxiao Wang, Sufang Zhang, Zhenzhong Zhang, Ernest Y C Lee, Marietta Y W T Lee Lin SH2013
2013 Valentina Aria, Mariarita De Felice, Roberta Di Perna, Shuji Uno, Hisao Masai, Juhani E Syvaoja, Barbara van Loon, Ulrich Hubscher, Francesca M Pisani Aria V2013
2012 Marietta Y W T Lee, Sufang Zhang, Szu Hua Sharon Lin, Jennifer Chea, Xiaoxiao Wang, Christine Leroy, Agnes Wong, Zhongtao Zhang, Ernest Y C Lee Lee MY2012
2012 Ashwini S Kamath-Loeb, Jiang-Cheng Shen, Michael W Schmitt, Lawrence A Loeb Kamath-Loeb AS2012
2012 Sufang Zhang, Yajing Zhou, Ali Sarkeshik, John Yates, Timothy M Thomson, Zhongtao Zhang, Ernest Y C Lee, Marietta Y W T Lee Zhang S2012
2012 Zhenxin Hu, Senthil K Perumal, Hongjun Yue, Stephen J Benkovic Hu Z2012
2012 Markku Vaara, Harri Itkonen, Tomi Hillukkala, Zhe Liu, Heinz Peter Nasheuer, Daniel Schaarschmidt, Helmut Pospiech, Juhani E Syväoja Vaara M2012
2012 Yajing Zhou, Xiao Meng, Sufang Zhang, Ernest Y C Lee, Marietta Y W T Lee Zhou Y2012
2012 Jennifer Chea, Sufang Zhang, Hong Zhao, Zhongtao Zhang, Ernest Y C Lee, Zbigniew Darzynkiewicz, Marietta Y W T Lee Chea J2012
2012 Zhenzhong Zhang, Sufang Zhang, Szu Hua Sharon Lin, Xiaoxiao Wang, Licheng Wu, Ernest Y C Lee, Marietta Y W T Lee Zhang Z2012
2011 Ling Hui Xu, Mei Huang, Shou Guo Fang, Ding Xiang Liu Xu LH2011
2011 Yujue Wang, Qian Zhang, Huiqing Chen, Xincang Li, Weijun Mai, Keping Chen, Sufang Zhang, Ernest Y C Lee, Marietta Y W T Lee, Yajing Zhou Wang Y2011
2011 Yanjiao Zhou, Huiqing Chen, Xincang Li, Yujue Wang, Keping Chen, Sufang Zhang, Xiao Meng, Ernest Y C Lee, Marietta Y W T Lee Zhou Y2011 Cloned or native,Tagged,Full length or truncated,Storage requirements,All properties
2011 Kazuki Kobayashi, Shin Nishiumi, Masayuki Nishida, Midori Hirai, Takeshi Azuma, Hiromi Yoshida, Yoshiyuki Mizushina, Masaru Yoshida Kobayashi K2011
2010 Xiao Meng, Yanjiao Zhou, Ernest Y C Lee, Marietta Y W T Lee, David N Frick Meng X2010
2010 Takeo Narita, Toshiki Tsurimoto, Junpei Yamamoto, Kana Nishihara, Kaori Ogawa, Eiji Ohashi, Terry Evans, Shigenori Iwai, Shunichi Takeda, Kouji Hirota Narita T2010 Template lesions,All properties
2010 Kensaku Sanefuji, Akinobu Taketomi, Tomohiro Iguchi, Keishi Sugimachi, Toru Ikegami, Yo-ichi Yamashita, Tomonobu Gion, Yuji Soejima, Ken Shirabe, Yoshihiko Maehara Sanefuji K2010
2010 Linda J Reha-Krantz Reha-Krantz LJ2010
2010 Stephanie A Nick McElhinny, Brian E Watts, Dinesh Kumar, Danielle L Watt, Else-Britt Lundström, Peter M J Burgers, Erik Johansson, Andrei Chabes, Thomas A Kunkel Nick McElhinny SA2010 KM,All properties
2010 Mark D Sutton Sutton MD2010
2010 Sandeep N Shah, Patricia L Opresko, Xiao Meng, Marietta Y W T Lee, Kristin A Eckert Shah SN2010
2010 Ken Hirano, Yuichiro Yoshida, Tomomi Ishido, Yukihisa Wada, Naoji Moriya, Naoshi Yamazaki, Yoshiyuki Mizushina, Yoshinobu Baba, Mitsuru Ishikawa Hirano K2010
2010 Christopher Van, Shan Yan, W Matthew Michael, Shou Waga, Karlene A Cimprich Van C2010
2009 Xiao Meng, Yanjiao Zhou, Sufang Zhang, Ernest Y C Lee, David N Frick, Marietta Y W T Lee Meng X2009
2009 Tahir H Tahirov, Kira S Makarova, Igor B Rogozin, Youri I Pavlov, Eugene V Koonin Tahirov TH2009
2009 Ruzaliya Fazlieva, Cynthia S Spittle, Darlene Morrissey, Harutoshi Hayashi, Hong Yan, Yoshihiro Matsumoto Fazlieva R2009
2009 Scott D McCulloch, Robert J Kokoska, Parie Garg, Peter M J Burgers, Thomas A Kunkel McCulloch SD2009
2009 Michael W Schmitt, Yoshihiro Matsumoto, Lawrence A Loeb Schmitt MW2009
2009 Yuki Matsui, Takahiko Hada, Naoki Maeda, Yoshihiro Sato, Yasuhiro Yamaguchi, Toshifumi Takeuchi, Masaharu Takemura, Fumio Sugawara, Kengo Sakaguchi, Hiromi Yoshida, Yoshiyuki Mizushina Matsui Y2009
2008 Yan Gao, Yanjiao Zhou, Bin Xie, Sufang Zhang, Amal A Rahmeh, Hua-Shan Huang, Marietta Y W T Lee, Ernest Y C Lee Gao Y2008
2008 Lionel Gellon, Dena R Carson, Jonathan P Carson, Bruce Demple Gellon L2008
2008 Lance D Langston, Mike E O'Donnell Langston LD2008
2008 Andrey G Baranovskiy, Nigar D Babayeva, Victoria G Liston, Igor B Rogozin, Eugene V Koonin, Youri I Pavlov, Dmitry G Vassylyev, Tahir H Tahirov Baranovskiy AG2008
2008 Laure Lemmens, Serge Urbach, Renaud Prudent, Claude Cochet, Giuseppe Baldacci, Patrick Hughes Lemmens L2008
2008 Nives Selak, Csanád Z Bachrati, Igor V Shevelev, Tobias Dietschy, Barbara van Loon, Anette Jacob, Ulrich Hübscher, Joerg D Hoheisel, Ian D Hickson, Igor Stagljar Selak N2008
2006 Anna K Rytkönen, Tomi Hillukkala, Markku Vaara, Miiko Sokka, Maarit Jokela, Raija Sormunen, Heinz Peter Nasheuer, Tamar Nethanel, Gabriel Kaufmann, Helmut Pospiech, Juhani E Syväoja Rytkönen AK2006
2006 Hao Li, Bin Xie, Yanjiao Zhou, Amal A Rahmeh, Sandra Trusa, Sufang Zhang, Yan Gao, Ernest Y C Lee, Marietta Y W T Lee Li H2006
2006 Geng Liu, Emma Warbrick Liu G2006
2006 Hao Li, Bin Xie, Amal A Rahmeh, Yanjiao Zhou, Marietta Y W T Lee Li H2006
2006 Jeong-Yun Choi, Goutam Chowdhury, Hong Zang, Karen C Angel, Choua C Vu, Lisa A Peterson, F Peter Guengerich Choi JY2006
2006 Jeong-Yun Choi, James S Stover, Karen C Angel, Goutam Chowdhury, Carmelo J Rizzo, F Peter Guengerich Choi JY2006
2005 J Richard G Pohler, Marit Otterlei, Emma Warbrick Pohler JR2005
2005 Jeong-Yun Choi, F Peter Guengerich Choi JY2005
2005 Bin Xie, Hao Li, Qi Wang, Suqing Xie, Amal A Rahmeh, Wei Dai, Marietta Y W T Lee Xie B2005
2005 Toshiki Tsurimoto, Ayako Shinozaki, Masaki Yano, Masayuki Seki, Takemi Enomoto Tsurimoto T2005
2004 Kenji Watanabe, Satoshi Tateishi, Michio Kawasuji, Toshiki Tsurimoto, Hirokazu Inoue, Masaru Yamaizumi Watanabe K2004
2004 Youri I Pavlov, Satoko Maki, Hisaji Maki, Thomas A Kunkel Pavlov YI2004 3-5' exo,5-3' exo,All properties
2003 Lingfeng Liu, Esther M Rodriguez-Belmonte, Nayef Mazloum, Bin Xie, Marietta Y W T Lee Liu L2003
2002 Vladimir N Podust, Long-Sheng Chang, Robert Ott, Grigory L Dianov, Ellen Fanning Podust VN2002
2002 Bin Xie, Nayef Mazloum, Lingfeng Liu, Amal A Rahmeh, Hao Li, Marietta Y W T Lee Xie B2002
2002 Naomi Suzuki, Eiji Ohashi, Alexander Kolbanovskiy, Nicholas E Geacintov, Arthur P Grollman, Haruo Ohmori, Shinya Shibutani Suzuki N2002
2002 Lajos Haracska, Louise Prakash, Satya Prakash Haracska L2002
2001 A J Podlutsky, Irina I Dianova, Vladimir N Podust, Vilhelm A Bohr, Grigory L Dianov Podlutsky AJ2001
2001 B Li, Marietta Y W T Lee Li B2001
2001 K Shikata, S Ohta, Kohei Yamada, C Obuse, Hirofumi Yoshikawa, Toshiki Tsurimoto Shikata K2001
2001 Yong Hwan Jin, R Obert, Peter M J Burgers, Thomas A Kunkel, Michael A Resnick, Dmitry A Gordenin Jin YH2001 3-5' exo,All properties
2001 M Ducoux, Serge Urbach, Giuseppe Baldacci, Ulrich Hübscher, Stéphane Koundrioukoff, J Christensen, Patrick Hughes Ducoux M2001
2000 A Perez, A Leon, Marietta Y W T Lee Perez A2000
2000 Lingfeng Liu, J Mo, Esther M Rodriguez-Belmonte, Marietta Y W T Lee Liu L2000
2000 Eiji Ohashi, Katarzyna Bebenek, Toshiro Matsuda, William J Feaver, Valerie L Gerlach, Errol C Friedberg, Haruo Ohmori, Thomas A Kunkel Ohashi E2000 Nucleotide Substitution Rate,All properties
2000 H J Einolf, F Peter Guengerich Einolf HJ2000 KM,kcat,All properties
2000 S W Wang, T Toda, R MacCallum, A L Harris, C Norbury Wang SW2000
2000 A M Szekely, Y H Chen, C Zhang, J Oshima, S M Weissman Szekely AM2000
2000 S J Araújo, F Tirode, F Coin, Helmut Pospiech, Juhani E Syväoja, M Stucki, Ulrich Hübscher, J M Egly, Richard D Wood Araújo SJ2000
2000 S Suzuki, Motoshi Suzuki, Shonen Yoshida Suzuki S2000
1998 S M Wu, Peiming Zhang, X R Zeng, S J Zhang, J Mo, B Q Li, Marietta Y W T Lee Wu SM1998
1998 Peiming Zhang, Younguk Sun, H Hsu, Linqi Zhang, Yongqing Zhang, Marietta Y W T Lee Zhang P1998
1997 Younguk Sun, Yanan Jiang, Peiming Zhang, S J Zhang, Yanjiao Zhou, B Q Li, N L Toomey, Marietta Y W T Lee Sun Y1997
1997 Jin-Qiu Zhou, H He, Cheng-Keat Tan, Kathleen M Downey, Antero G So Zhou JQ1997
1996 S Ceccotti, G Aquilina, Peter Macpherson, Masami Yamada, Peter Karran, Margherita Bignami Ceccotti S1996
1996 Dmitry Ju Mozzherin, Maeve McConnell, M V Jasko, A A Krayevsky, Cheng-Keat Tan, Kathleen M Downey, Paul A Fisher Mozzherin DJ1996
1996 Polina V Shcherbakova, V N Noskov, M R Pshenichnov, Youri I Pavlov Shcherbakova PV1996
1996 F B Perler, Sandeep Kumar, H Kong Perler FB1996 Full length or truncated,3-5' exo,5-3' exo,Molecular Weight,All properties
1996 Jacqueline M Gulbis, Zvi Kelman, Jerard Hurwitz, Mike E O'Donnell, John Kuriyan Gulbis JM1996
1996 Jin-Qiu Zhou, Cheng-Keat Tan, Antero G So, Kathleen M Downey Zhou JQ1996
1995 S J Zhang, X R Zeng, Peiming Zhang, N L Toomey, R Y Chuang, Long-Sheng Chang, Marietta Y W T Lee Zhang SJ1995
1995 Peiming Zhang, S J Zhang, Zhenzhong Zhang, J F Woessner, Marietta Y W T Lee Zhang P1995
1995 Long-Sheng Chang, L Zhao, L Zhu, M L Chen, Marietta Y W T Lee Chang LS1995
1995 T Melendy, Juhan Sedman, A Stenlund Melendy T1995
1995 Federico Focher, Giovanni Maga, A Bendiscioli, M Capobianco, F Colonna, A Garbesi, Silvio Spadari Focher F1995
1995 Yanan Jiang, S J Zhang, S M Wu, Marietta Y W T Lee Jiang Y1995
1995 Peiming Zhang, I Frugulhetti, Yanan Jiang, G L Holt, R C Condit, Marietta Y W T Lee Zhang P1995
1994 Takehisa Matsumoto, S Hata, I Suzuka, Junji Hashimoto Matsumoto T1994
1994 X R Zeng, H Hao, Yanan Jiang, Marietta Y W T Lee Zeng XR1994
1994 Xincang Li, Peter M J Burgers Li X1994
1994 L M Podust, Vladimir N Podust, C Floth, Ulrich Hübscher Podust LM1994
1993 S H Lee Lee SH1993
1993 Vladimir N Podust, Ulrich Hübscher Podust VN1993
1993 Dmitry A Gordenin, K S Lobachev, N P Degtyareva, A L Malkova, E Perkins, Michael A Resnick Gordenin DA1993
1992 H Hao, Yanan Jiang, S J Zhang, Peiming Zhang, R X Zeng, Marietta Y W T Lee Hao H1992
1992 Silvio Spadari, Federico Focher, Ulrich Hübscher Spadari S1992
1992 Dmitry A Gordenin, A L Malkova, A Peterzen, V N Kulikov, Youri I Pavlov, E Perkins, Michael A Resnick Gordenin DA1992
1992 Unknown1992
1992 C L Yang, Long-Sheng Chang, Peiming Zhang, H Hao, L Zhu, N L Toomey, Marietta Y W T Lee Yang CL1992
1992 R R Kemper, E R Ahn, Peiming Zhang, Marietta Y W T Lee, M Rabin Kemper RR1992
1991 T Weiser, M Gassmann, P Thömmes, Elena Ferrari, P Hafkemeyer, Ulrich Hübscher Weiser T1991 Full length or truncated,Specific Activity,Processivity,3-5' exo,5-3' exo,Molecular Weight,3-5' Exo Specific Activity,RNase H,All properties
1991 Marietta Y W T Lee, Y Q Jiang, S J Zhang, N L Toomey Lee MY1991
1991 B A Fox, D J Bzik Fox BA1991
1991 D W Chung, J A Zhang, Cheng-Keat Tan, E W Davie, Antero G So, Kathleen M Downey Chung DW1991
1990 Peter M J Burgers, Robert A Bambara, Judith L Campbell, L M Chang, Kathleen M Downey, Ulrich Hübscher, Marietta Y W T Lee, Stuart Linn, Antero G So, Silvio Spadari Burgers PM1990
1989 Federico Focher, M Gassmann, P Hafkemeyer, Elena Ferrari, Silvio Spadari, Ulrich Hübscher Focher F1989
1988 G A Bauer, Peter M J Burgers Bauer GA1988
1986 Marietta Y W T Lee, N L Toomey Lee MY1986
1986 Cheng-Keat Tan, C Castillo, Antero G So, Kathleen M Downey Tan CK1986
1981 M Geuskens, N Hardt, G Pedrali-Noy, Silvio Spadari Geuskens M1981
1980 G Pedrali-Noy, Silvio Spadari, A Miller-Faurès, A O Miller, J Kruppa, G Koch Pedrali-Noy G1980
1976 J J Byrnes, Kathleen M Downey, V L Black, Antero G So Byrnes JJ1976
Protein sequence:
DNA sequence:
All Polymerases | 26 Results

Using Polbase tables:

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