Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1.

Abstract:

We have used a structure-based approach to design a novel series of ...

Polymerases:

Topics:

Health/Disease, Structure and Structure/Function, Reverse Transcriptase

Status:

new topics/pols set partial results complete validated

Results:

Polymerase Reference Property Result Context
HIV RT Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1. Reverse Transcriptase Activity Yes
HIV RT Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1. Associated condition HIV

Structures:

1TL3 1TL1 1TKZ 1TKT