Analyzing fidelity of DNA polymerases.

Methods in enzymology (1995), Volume 262, Page 217

Polymerases:

Topics:

Fidelity

Status:

new topics/pols set partial results complete validated

Results:

Polymerase Reference Property Result Context
Bovine pol epsilon Bebenek K1995 Overall Error Rate 0.0007 errors/bp Technique: M13mp2 forward mutation assay
Bovine pol epsilon Bebenek K1995 Overall Error Rate 5E-06 errors/bp Technique: M13mp2 opal codon reversion assay
Klenow fragment Bebenek K1995 Frameshift Error Rate 8E-05 errors/bp Technique: Reversion
Klenow fragment Bebenek K1995 Overall Error Rate 0.0052 errors/bp Technique: M13mp2 forward mutation assay
Klenow fragment Bebenek K1995 Overall Error Rate 7.7E-05 errors/bp Technique: M13mp2 opal codon reversion assay
HIV RT Bebenek K1995 Frameshift Error Rate 0.0047 errors/bp Technique: Reversion
HIV RT Bebenek K1995 Overall Error Rate 0.08 errors/bp Technique: M13mp2 forward mutation assay
HIV RT Bebenek K1995 Overall Error Rate 0.0001 errors/bp Technique: M13mp2 opal codon reversion assay

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