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Kunkel TA

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Publications:

Title Authors Year Journal
DNA Polymerase λ Inactivation by Oxidized Abasic Sites. Kunkel TA 2013 Biochemistry
DNA polymerase δ stalls on telomeric lagging strand templates independently from G-quadruplex formation. Kunkel TA 2013 Nucleic acids research
Altered Ig Hypermutation Pattern and Frequency in Complementary Mouse Models of DNA Polymerase ζ Activity. Kunkel TA 2012 Journal of immunology (Baltimore, Md. : 1950)
RNase H2-Initiated Ribonucleotide Excision Repair. Kunkel TA 2012 Molecular cell
Ribonucleotide incorporation, proofreading and bypass by human DNA polymerase δ Kunkel TA 2012 DNA repair
Exonuclease 1 preferentially repairs mismatches generated by DNA polymerase α Kunkel TA 2012 DNA repair
The catalytic cycle for ribonucleotide incorporation by human DNA Pol λ Kunkel TA 2012 Nucleic acids research
Proofreading of ribonucleotides inserted into DNA by yeast DNA polymerase ɛ Kunkel TA 2012 DNA repair
The in vitro fidelity of yeast DNA polymerase δ and polymerase ε holoenzymes during dinucleotide microsatellite DNA synthesis. Kunkel TA 2011 DNA repair
Mismatch repair-independent tandem repeat sequence instability resulting from ribonucleotide incorporation by DNA polymerase ε. Kunkel TA 2011 DNA repair
Replication of ribonucleotide-containing DNA templates by yeast replicative polymerases. Kunkel TA 2011 DNA repair
Unexpected role for Helicobacter pylori DNA polymerase I as a source of genetic variability. Kunkel TA 2011 PLoS genetics
Kinetic analysis of the unique error signature of human DNA polymerase ν Kunkel TA 2011 Biochemistry
Replication infidelity via a mismatch with Watson-Crick geometry. Kunkel TA 2011 Proceedings of the National Academy of Sciences of the United States of America
The interaction between DNA polymerase lambda and anticancer nucleoside analogs. Kunkel TA 2010 The Journal of biological chemistry
Differential correction of lagging-strand replication errors made by DNA polymerases {alpha} and {delta}. Kunkel TA 2010 Proceedings of the National Academy of Sciences of the United States of America
Mutator phenotypes due to DNA replication infidelity. Kunkel TA 2010 Seminars in cancer biology
Genome-wide model for the normal eukaryotic DNA replication fork. Kunkel TA 2010 Proceedings of the National Academy of Sciences of the United States of America
Genome instability due to ribonucleotide incorporation into DNA. Kunkel TA 2010 Nature chemical biology
Evolutionary conservation of residues in vertebrate DNA polymerase N conferring low fidelity and bypass activity. Kunkel TA 2010 Nucleic acids research
Inhibition of short patch and long patch base excision repair by an oxidized abasic site. Kunkel TA 2010 Biochemistry
Refolding active human DNA polymerase nu from inclusion bodies. Kunkel TA 2010 Protein Expr Purif
Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases. Kunkel TA 2010 Proceedings of the National Academy of Sciences of the United States of America
Loop 1 modulates the fidelity of DNA polymerase {lambda} Kunkel TA 2010 Nucleic acids research
Mismatch repair-independent increase in spontaneous mutagenesis in yeast lacking non-essential subunits of DNA polymerase epsilon. Kunkel TA 2010 PLoS Genet
Low-fidelity DNA synthesis by the L979F mutator derivative of Saccharomyces cerevisiae DNA polymerase zeta. Kunkel TA 2009 Nucleic acids research
The efficiency and fidelity of 8-oxo-guanine bypass by DNA polymerases delta and eta. Kunkel TA 2009 Nucleic acids research
Characterization of a natural mutator variant of human DNA polymerase lambda which promotes chromosomal instability by compromising NHEJ. Kunkel TA 2009 PloS one
Template strand scrunching during DNA gap repair synthesis by human polymerase lambda. Kunkel TA 2009 Nature structural & molecular biology
Division of labor at the eukaryotic replication fork. Kunkel TA 2008 Molecular cell
Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase gamma replication fidelity. Kunkel TA 2008 Nucleic acids research
Characterization of a replicative DNA polymerase mutant with reduced fidelity and increased translesion synthesis capacity. Kunkel TA 2008 Nucleic acids research
Dividing the workload at a eukaryotic replication fork. Kunkel TA 2008 Trends Cell Biol
Low-fidelity DNA synthesis by human DNA polymerase theta. Kunkel TA 2008 Nucleic acids research
Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase lambda. Kunkel TA 2008 EMBO Rep
The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases. Kunkel TA 2008 Cell research
Tolerance for 8-oxoguanine but not thymine glycol in alignment-based gap filling of partially complementary double-strand break ends by DNA polymerase lambda in human nuclear extracts. Kunkel TA 2008 Nucleic acids research
Catalytic mechanism of human DNA polymerase lambda with Mg2+ and Mn2+ from ab initio quantum mechanical/molecular mechanical studies. Kunkel TA 2008 DNA repair
DNA polymerase epsilon: a polymerase of unusual size (and complexity). Kunkel TA 2008 Prog Nucleic Acid Res Mol Biol
Role of the catalytic metal during polymerization by DNA polymerase lambda. Kunkel TA 2007 DNA repair
The X family portrait: structural insights into biological functions of X family polymerases. Kunkel TA 2007 DNA repair
Yeast DNA polymerase epsilon participates in leading-strand DNA replication. Kunkel TA 2007 Science
Regulation of B family DNA polymerase fidelity by a conserved active site residue: characterization of M644W, M644L and M644F mutants of yeast DNA polymerase epsilon. Kunkel TA 2007 Nucleic acids research
Inefficient proofreading and biased error rates during inaccurate DNA synthesis by a mutant derivative of Saccharomyces cerevisiae DNA polymerase delta. Kunkel TA 2007 The Journal of biological chemistry
RNA-templated DNA repair. Kunkel TA 2007 Nature
Replication of 2-hydroxyadenine-containing DNA and recognition by human MutSalpha. Kunkel TA 2007 DNA repair
Mutator alleles of yeast DNA polymerase zeta. Kunkel TA 2007 DNA repair
A unique error signature for human DNA polymerase nu. Kunkel TA 2007 DNA repair
Effects of accessory proteins on the bypass of a cis-syn thymine-thymine dimer by Saccharomyces cerevisiae DNA polymerase eta. Kunkel TA 2007 Biochemistry
Structural insight into the substrate specificity of DNA Polymerase mu. Kunkel TA 2007 Nature structural & molecular biology
Multiple solutions to inefficient lesion bypass by T7 DNA polymerase. Kunkel TA 2006 DNA repair
Measuring the fidelity of translesion DNA synthesis. Kunkel TA 2006 Methods in enzymology
Increased susceptibility to UV-induced skin carcinogenesis in polymerase eta-deficient mice. Kunkel TA 2006 Cancer research
The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins. Kunkel TA 2006 Nucleic acids research
Promiscuous mismatch extension by human DNA polymerase lambda. Kunkel TA 2006 Nucleic acids research
RPA and PCNA suppress formation of large deletion errors by yeast DNA polymerase delta. Kunkel TA 2006 Nucleic acids research
Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer. Kunkel TA 2006 Proceedings of the National Academy of Sciences of the United States of America
Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase. Kunkel TA 2006 Cell
Evidence that errors made by DNA polymerase alpha are corrected by DNA polymerase delta. Kunkel TA 2006 Current biology : CB
A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining. Kunkel TA 2005 Molecular cell
Structure-function studies of DNA polymerase lambda. Kunkel TA 2005 DNA repair
Saccharomyces cerevisiae DNA polymerase delta: high fidelity for base substitutions but lower fidelity for single- and multi-base deletions. Kunkel TA 2005 The Journal of biological chemistry
A closed conformation for the Pol lambda catalytic cycle. Kunkel TA 2005 Nature structural & molecular biology
The multiple biological roles of the 3'-->5' exonuclease of Saccharomyces cerevisiae DNA polymerase delta require switching between the polymerase and exonuclease domains. Kunkel TA 2005 Molecular and cellular biology
Biochemical properties of Saccharomyces cerevisiae DNA polymerase IV. Kunkel TA 2005 The Journal of biological chemistry
A lysine residue in the fingers subdomain of T7 DNA polymerase modulates the miscoding potential of 8-oxo-7,8-dihydroguanosine. Kunkel TA 2005 Structure (London, England : 1993)
Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. Kunkel TA 2004 The EMBO journal
DNA replication fidelity. Kunkel TA 2004 The Journal of biological chemistry
A structural solution for the DNA polymerase lambda-dependent repair of DNA gaps with minimal homology. Kunkel TA 2004 Molecular cell
Preferential cis-syn thymine dimer bypass by DNA polymerase eta occurs with biased fidelity. Kunkel TA 2004 Nature
Pol iota is a candidate for the mouse pulmonary adenoma resistance 2 locus, a major modifier of chemically induced lung neoplasia. Kunkel TA 2004 Cancer research
Enzymatic switching for efficient and accurate translesion DNA replication. Kunkel TA 2004 Nucleic acids research
Efficiency, fidelity and enzymatic switching during translesion DNA synthesis. Kunkel TA 2004 Cell cycle (Georgetown, Tex.)
Investigating the role of the little finger domain of Y-family DNA polymerases in low fidelity synthesis and translesion replication. Kunkel TA 2004 The Journal of biological chemistry
Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations. Kunkel TA 2004 BMC biology
Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts. Kunkel TA 2004 The Journal of biological chemistry
Functions of DNA polymerases. Kunkel TA 2004 Adv Protein Chem
Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. Kunkel TA 2003 The Journal of biological chemistry
Solution structure of the lyase domain of human DNA polymerase lambda. Kunkel TA 2003 Biochemistry
Roles of Saccharomyces cerevisiae DNA polymerases Poleta and Polzeta in response to irradiation by simulated sunlight. Kunkel TA 2003 Nucleic acids research
Cadmium is a mutagen that acts by inhibiting mismatch repair. Kunkel TA 2003 Nature genetics
Mutations in DNA polymerase gamma cause error prone DNA synthesis in human mitochondrial disorders. Kunkel TA 2003 Acta Biochim Pol
The base substitution fidelity of DNA polymerase beta-dependent single nucleotide base excision repair. Kunkel TA 2003 The Journal of biological chemistry
Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates. Kunkel TA 2003 DNA repair
The frameshift infidelity of human DNA polymerase lambda. Implications for function. Kunkel TA 2003 The Journal of biological chemistry
Unique error signature of the four-subunit yeast DNA polymerase epsilon. Kunkel TA 2003 The Journal of biological chemistry
Considering the cancer consequences of altered DNA polymerase function. Kunkel TA 2003 Cancer Cell
Localization of the deoxyribose phosphate lyase active site in human DNA polymerase iota by controlled proteolysis. Kunkel TA 2003 The Journal of biological chemistry
The efficiency and specificity of apurinic/apyrimidinic site bypass by human DNA polymerase eta and Sulfolobus solfataricus Dpo4. Kunkel TA 2003 The Journal of biological chemistry
Family growth: the eukaryotic DNA polymerase revolution. Kunkel TA 2002 Cell Mol Life Sci
Correlation of somatic hypermutation specificity and A-T base pair substitution errors by DNA polymerase eta during copying of a mouse immunoglobulin kappa light chain transgene. Kunkel TA 2002 Proceedings of the National Academy of Sciences of the United States of America
Low fidelity DNA synthesis by a y family DNA polymerase due to misalignment in the active site. Kunkel TA 2002 The Journal of biological chemistry
Active site mutation in DNA polymerase gamma associated with progressive external ophthalmoplegia causes error-prone DNA synthesis. Kunkel TA 2002 The Journal of biological chemistry
DNA polymerase lambda, a novel DNA repair enzyme in human cells. Kunkel TA 2002 The Journal of biological chemistry
Discrimination against purine-pyrimidine mispairs in the polymerase active site of DNA polymerase I: a structural explanation. Kunkel TA 2002 Proceedings of the National Academy of Sciences of the United States of America
The fidelity of human DNA polymerase gamma with and without exonucleolytic proofreading and the p55 accessory subunit. Kunkel TA 2001 The Journal of biological chemistry
In vivo consequences of putative active site mutations in yeast DNA polymerases alpha, epsilon, delta, and zeta. Kunkel TA 2001 Genetics
Proofreading of DNA polymerase eta-dependent replication errors. Kunkel TA 2001 The Journal of biological chemistry
Error rate and specificity of human and murine DNA polymerase eta. Kunkel TA 2001 Journal of molecular biology
Identification of an intrinsic 5'-deoxyribose-5-phosphate lyase activity in human DNA polymerase lambda: a possible role in base excision repair. Kunkel TA 2001 The Journal of biological chemistry
Somatic mutation hotspots correlate with DNA polymerase eta error spectrum. Kunkel TA 2001 Nat Immunol
The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability. Kunkel TA 2001 Proceedings of the National Academy of Sciences of the United States of America
Mutator effects of overproducing DNA polymerase eta (Rad30) and its catalytically inactive variant in yeast. Kunkel TA 2001 Mutation research
5'-Deoxyribose phosphate lyase activity of human DNA polymerase iota in vitro. Kunkel TA 2001 Science
Vertical-scanning mutagenesis of a critical tryptophan in the "minor groove binding track" of HIV-1 reverse transcriptase. Major groove DNA adducts identify specific protein interactions in the minor groove. Kunkel TA 2000 The Journal of biological chemistry
Human DNA polymerase kappa: a novel DNA polymerase of unknown biological function encoded by the DINB1 gene. Kunkel TA 2000 Cold Spring Harbor symposia on quantitative biology
Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene. Kunkel TA 2000 The Journal of biological chemistry
Minor groove interactions at the DNA polymerase beta active site modulate single-base deletion error rates. Kunkel TA 2000 The Journal of biological chemistry
Low fidelity DNA synthesis by human DNA polymerase-eta. Kunkel TA 2000 Nature
DNA replication fidelity. Kunkel TA 2000 Annual review of biochemistry
Side chains that influence fidelity at the polymerase active site of Escherichia coli DNA polymerase I (Klenow fragment). Kunkel TA 1999 The Journal of biological chemistry
Deletion errors generated during replication of CAG repeats. Kunkel TA 1999 Nucleic acids research
Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene. Kunkel TA 1999 Proceedings of the National Academy of Sciences of the United States of America
The fidelity of DNA polymerase beta during distributive and processive DNA synthesis. Kunkel TA 1999 The Journal of biological chemistry
Residues in the alphaH and alphaI helices of the HIV-1 reverse transcriptase thumb subdomain required for the specificity of RNase H-catalyzed removal of the polypurine tract primer. Kunkel TA 1999 The Journal of biological chemistry
Uniquely altered DNA replication fidelity conferred by an amino acid change in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase. Kunkel TA 1999 The Journal of biological chemistry
The base substitution fidelity of HIV-1 reverse transcriptase on DNA and RNA templates probed with 8-oxo-deoxyguanosine triphosphate. Kunkel TA 1999 Mutation research
Base substitution specificity of DNA polymerase beta depends on interactions in the DNA minor groove. Kunkel TA 1999 The Journal of biological chemistry
Vertical-scanning mutagenesis of a critical tryptophan in the minor groove binding track of HIV-1 reverse transcriptase. Molecular nature of polymerase-nucleic acid interactions. Kunkel TA 1998 The Journal of biological chemistry
Effect of accessory proteins on T4 DNA polymerase replication fidelity. Kunkel TA 1998 Journal of molecular biology
A minor groove binding track in reverse transcriptase. Kunkel TA 1997 Nat Struct Biol
Probing structure/function relationships of HIV-1 reverse transcriptase with styrene oxide N2-guanine adducts. Kunkel TA 1997 The Journal of biological chemistry
Correction of hypermutability, N-methyl-N'-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6. Kunkel TA 1997 Cancer research
Base miscoding and strand misalignment errors by mutator Klenow polymerases with amino acid substitutions at tyrosine 766 in the O helix of the fingers subdomain. Kunkel TA 1997 The Journal of biological chemistry
Role of the "helix clamp" in HIV-1 reverse transcriptase catalytic cycling as revealed by alanine-scanning mutagenesis. Kunkel TA 1996 The Journal of biological chemistry
Base analog N6-hydroxylaminopurine mutagenesis in Escherichia coli: genetic control and molecular specificity. Kunkel TA 1996 Mutation research
Exonucleolytic proofreading during replication of repetitive DNA. Kunkel TA 1996 Biochemistry
A thumb subdomain mutant of the large fragment of Escherichia coli DNA polymerase I with reduced DNA binding affinity, processivity, and frameshift fidelity. Kunkel TA 1996 The Journal of biological chemistry
Enzyme-DNA interactions required for efficient nucleotide incorporation and discrimination in human DNA polymerase beta. Kunkel TA 1996 The Journal of biological chemistry
Reduced frameshift fidelity and processivity of HIV-1 reverse transcriptase mutants containing alanine substitutions in helix H of the thumb subdomain. Kunkel TA 1995 The Journal of biological chemistry
Analyzing fidelity of DNA polymerases. Kunkel TA 1995 Methods in enzymology
Purification and properties of wild-type and exonuclease-deficient DNA polymerase II from Escherichia coli. Kunkel TA 1995 The Journal of biological chemistry
DNA replication fidelity with 8-oxodeoxyguanosine triphosphate. Kunkel TA 1994 Biochemistry
Structure/function studies of human immunodeficiency virus type 1 reverse transcriptase. Alanine scanning mutagenesis of an alpha-helix in the thumb subdomain. Kunkel TA 1994 The Journal of biological chemistry
Error-prone replication of repeated DNA sequences by T7 DNA polymerase in the absence of its processivity subunit. Kunkel TA 1994 Proceedings of the National Academy of Sciences of the United States of America
A beta-like DNA polymerase from the mitochondrion of the trypanosomatid Crithidia fasciculata. Kunkel TA 1994 The Journal of biological chemistry
Error-prone polymerization by HIV-1 reverse transcriptase. Contribution of template-primer misalignment, miscoding, and termination probability to mutational hot spots. Kunkel TA 1993 The Journal of biological chemistry
Fidelity of DNA synthesis catalyzed by human DNA polymerase alpha and HIV-1 reverse transcriptase: effect of reaction pH. Kunkel TA 1993 Nucleic acids research
Mechanism of HIV-1 reverse transcriptase. Termination of processive synthesis on a natural DNA template is influenced by the sequence of the template-primer stem. Kunkel TA 1993 The Journal of biological chemistry
Effect of reaction pH on the fidelity and processivity of exonuclease-deficient Klenow polymerase. Kunkel TA 1993 The Journal of biological chemistry
Structure/function studies of HIV-1(1) reverse transcriptase: dimerization-defective mutant L289K. Kunkel TA 1993 Biochemistry
Unequal human immunodeficiency virus type 1 reverse transcriptase error rates with RNA and DNA templates. Kunkel TA 1992 Proceedings of the National Academy of Sciences of the United States of America
The effects of dNTP pool imbalances on frameshift fidelity during DNA replication. Kunkel TA 1992 The Journal of biological chemistry
Biochemical studies on the reverse transcriptase and RNase H activities from human immunodeficiency virus strains resistant to 3'-azido-3'-deoxythymidine. Kunkel TA 1992 The Journal of biological chemistry
Exonucleolytic proofreading of leading and lagging strand DNA replication errors. Kunkel TA 1991 Proceedings of the National Academy of Sciences of the United States of America
The fidelity of DNA synthesis by the catalytic subunit of yeast DNA polymerase alpha alone and with accessory proteins. Kunkel TA 1991 Mutation research
Heteroduplex repair in extracts of human HeLa cells. Kunkel TA 1991 The Journal of biological chemistry
Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity. Kunkel TA 1991 Proceedings of the National Academy of Sciences of the United States of America
Fidelity of mammalian DNA replication and replicative DNA polymerases. Kunkel TA 1991 Biochemistry
DNA polymerase fidelity and the polymerase chain reaction. Kunkel TA 1991 PCR Methods Appl
Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme. Kunkel TA 1990 The Journal of biological chemistry
High fidelity DNA synthesis by the Thermus aquaticus DNA polymerase. Kunkel TA 1990 Nucleic acids research
The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I. Kunkel TA 1990 The Journal of biological chemistry
Fidelity of animal cell DNA polymerases alpha and delta and of a human DNA replication complex. Kunkel TA 1990 Basic life sciences
Frameshift errors initiated by nucleotide misincorporation. Kunkel TA 1990 Proceedings of the National Academy of Sciences of the United States of America
The use of native T7 DNA polymerase for site-directed mutagenesis. Kunkel TA 1989 Nucleic acids research
Kinetic analysis of base substitution mutagenesis by transient misalignment of DNA and by miscoding. Kunkel TA 1989 The Journal of biological chemistry
Exonucleolytic proofreading by a mammalian DNA polymerase. Kunkel TA 1989 Biochemistry
Fidelity of DNA polymerase I and the DNA polymerase I-DNA primase complex from Saccharomyces cerevisiae. Kunkel TA 1989 Molecular and cellular biology
Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro. Kunkel TA 1989 Molecular and cellular biology
Specificity and mechanism of error-prone replication by human immunodeficiency virus-1 reverse transcriptase. Kunkel TA 1989 The Journal of biological chemistry
The accuracy of reverse transcriptase from HIV-1. Kunkel TA 1988 Science (New York, N.Y.)
Exonucleolytic proofreading enhances the fidelity of DNA synthesis by chick embryo DNA polymerase-gamma. Kunkel TA 1988 The Journal of biological chemistry
Purification and characterization of bacteriophage N4-induced DNA polymerase. Kunkel TA 1988 The Journal of biological chemistry
Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase. Kunkel TA 1988 Biochemistry
Exonucleolytic proofreading. Kunkel TA 1988 Cell
Fidelity of a human cell DNA replication complex. Kunkel TA 1988 Proceedings of the National Academy of Sciences of the United States of America
Base substitution mutagenesis by terminal transferase: its role in somatic mutagenesis. Kunkel TA 1987 Mutation research
Exonucleolytic proofreading by calf thymus DNA polymerase delta. Kunkel TA 1987 Proceedings of the National Academy of Sciences of the United States of America
Rearrangements of DNA mediated by terminal transferase. Kunkel TA 1986 Proceedings of the National Academy of Sciences of the United States of America
On the fidelity of DNA synthesis. Pyrophosphate-induced misincorporation allows detection of two proofreading mechanisms. Kunkel TA 1986 The Journal of biological chemistry
The base substitution fidelity of eucaryotic DNA polymerases. Mispairing frequencies, site preferences, insertion preferences, and base substitution by dislocation. Kunkel TA 1986 The Journal of biological chemistry
Mutagenesis in vitro by DNA polymerases alpha, beta and gamma. Kunkel TA 1986 Progress in clinical and biological research
Frameshift mutagenesis by eucaryotic DNA polymerases in vitro. Kunkel TA 1986 The Journal of biological chemistry
The mutational specificity of DNA polymerases-alpha and -gamma during in vitro DNA synthesis. Kunkel TA 1985 The Journal of biological chemistry
The mutational specificity of DNA polymerase-beta during in vitro DNA synthesis. Production of frameshift, base substitution, and deletion mutations. Kunkel TA 1985 The Journal of biological chemistry
On the fidelity of DNA replication. The accuracy of T4 DNA polymerases in copying phi X174 DNA in vitro. Kunkel TA 1984 The Journal of biological chemistry
Depurination-induced infidelity of deoxyribonucleic acid synthesis with purified deoxyribonucleic acid replication proteins in vitro. Kunkel TA 1983 Biochemistry
Infidelity of DNA synthesis associated with bypass of apurinic sites. Kunkel TA 1983 Proceedings of the National Academy of Sciences of the United States of America
The mutagenic effect of deoxynucleotide substrate imbalances during DNA synthesis with mammalian DNA polymerases. Kunkel TA 1982 Mutation research
Depurination of DNA as a possible mutagenic pathway for cells. Kunkel TA 1982 Basic life sciences
On the fidelity of DNA replication. Effect of the next nucleotide on proofreading. Kunkel TA 1981 The Journal of biological chemistry
Fidelity of mammalian DNA polymerases. Kunkel TA 1981 Science
Deoxynucleoside [1-thio]triphosphates prevent proofreading during in vitro DNA synthesis. Kunkel TA 1981 Proceedings of the National Academy of Sciences of the United States of America
On the fidelity of DNA replication. The accuracy of Escherichia coli DNA polymerase I in copying natural DNA in vitro. Kunkel TA 1980 The Journal of biological chemistry
Mutagenesis in vitro by DNA polymerase from an RNA tumour virus. Kunkel TA 1979 Nature
Single-strand binding protein enhances fidelity of DNA synthesis in vitro. Kunkel TA 1979 Proceedings of the National Academy of Sciences of the United States of America
Distinctive properties of mammalian DNA polymerases. Kunkel TA 1979 Biochimica et biophysica acta
On the fidelity of DNA replication. Effect of divalent metal ion activators and deoxyrionucleoside triphosphate pools on in vitro mutagenesis. Kunkel TA 1979 The Journal of biological chemistry
Purification and properties of DNA polymerase-beta from guinea pig liver. Kunkel TA 1978 Biochimica et biophysica acta
Novikoff hepatoma deoxyribonucleic acid polymerase. Sensitivity of the beta-polymerase to sulfhydryl blocking agents. Kunkel TA 1976 Nucleic acids research
Isolation and purification of mediators of cell proliferation. Kunkel TA 1975 Archives of surgery (Chicago, Ill. : 1960)
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