Bebenek K

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Title	Authors	Year	Journal
Sustained active site rigidity during synthesis by human DNA polymerase μ.	Bebenek K	2014	Nature structural & molecular biology
DNA Polymerase λ Inactivation by Oxidized Abasic Sites.	Bebenek K	2013	Biochemistry
Altered Ig Hypermutation Pattern and Frequency in Complementary Mouse Models of DNA Polymerase ζ Activity.	Bebenek K	2012	Journal of immunology (Baltimore, Md. : 1950)
The catalytic cycle for ribonucleotide incorporation by human DNA Pol λ	Bebenek K	2012	Nucleic acids research
Replication infidelity via a mismatch with Watson-Crick geometry.	Bebenek K	2011	Proceedings of the National Academy of Sciences of the United States of America
Loop 1 modulates the fidelity of DNA polymerase {lambda}	Bebenek K	2010	Nucleic acids research
Inhibition of short patch and long patch base excision repair by an oxidized abasic site.	Bebenek K	2010	Biochemistry
Template strand scrunching during DNA gap repair synthesis by human polymerase lambda.	Bebenek K	2009	Nature structural & molecular biology
Characterization of a natural mutator variant of human DNA polymerase lambda which promotes chromosomal instability by compromising NHEJ.	Bebenek K	2009	PloS one
Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase lambda.	Bebenek K	2008	EMBO Rep
Catalytic mechanism of human DNA polymerase lambda with Mg2+ and Mn2+ from ab initio quantum mechanical/molecular mechanical studies.	Bebenek K	2008	DNA repair
Tolerance for 8-oxoguanine but not thymine glycol in alignment-based gap filling of partially complementary double-strand break ends by DNA polymerase lambda in human nuclear extracts.	Bebenek K	2008	Nucleic acids research
Structural insight into the substrate specificity of DNA Polymerase mu.	Bebenek K	2007	Nature structural & molecular biology
Multiple functions of DNA polymerases.	Bebenek K	2007	Critical reviews in plant sciences
RNA-templated DNA repair.	Bebenek K	2007	Nature
The X family portrait: structural insights into biological functions of X family polymerases.	Bebenek K	2007	DNA repair
Role of the catalytic metal during polymerization by DNA polymerase lambda.	Bebenek K	2007	DNA repair
Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase.	Bebenek K	2006	Cell
Promiscuous mismatch extension by human DNA polymerase lambda.	Bebenek K	2006	Nucleic acids research
A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining.	Bebenek K	2005	Molecular cell
Structure-function studies of DNA polymerase lambda.	Bebenek K	2005	DNA repair
A closed conformation for the Pol lambda catalytic cycle.	Bebenek K	2005	Nature structural & molecular biology
Biochemical properties of Saccharomyces cerevisiae DNA polymerase IV.	Bebenek K	2005	The Journal of biological chemistry
A lysine residue in the fingers subdomain of T7 DNA polymerase modulates the miscoding potential of 8-oxo-7,8-dihydroguanosine.	Bebenek K	2005	Structure (London, England : 1993)
Pol iota is a candidate for the mouse pulmonary adenoma resistance 2 locus, a major modifier of chemically induced lung neoplasia.	Bebenek K	2004	Cancer research
Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts.	Bebenek K	2004	The Journal of biological chemistry
A structural solution for the DNA polymerase lambda-dependent repair of DNA gaps with minimal homology.	Bebenek K	2004	Molecular cell
Functions of DNA polymerases.	Bebenek K	2004	Adv Protein Chem
Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates.	Bebenek K	2003	DNA repair
The base substitution fidelity of DNA polymerase beta-dependent single nucleotide base excision repair.	Bebenek K	2003	The Journal of biological chemistry
Solution structure of the lyase domain of human DNA polymerase lambda.	Bebenek K	2003	Biochemistry
Localization of the deoxyribose phosphate lyase active site in human DNA polymerase iota by controlled proteolysis.	Bebenek K	2003	The Journal of biological chemistry
The frameshift infidelity of human DNA polymerase lambda. Implications for function.	Bebenek K	2003	The Journal of biological chemistry
Family growth: the eukaryotic DNA polymerase revolution.	Bebenek K	2002	Cell Mol Life Sci
DNA polymerase lambda, a novel DNA repair enzyme in human cells.	Bebenek K	2002	The Journal of biological chemistry
Low fidelity DNA synthesis by a y family DNA polymerase due to misalignment in the active site.	Bebenek K	2002	The Journal of biological chemistry
Error rate and specificity of human and murine DNA polymerase eta.	Bebenek K	2001	Journal of molecular biology
Somatic mutation hotspots correlate with DNA polymerase eta error spectrum.	Bebenek K	2001	Nat Immunol
Identification of an intrinsic 5'-deoxyribose-5-phosphate lyase activity in human DNA polymerase lambda: a possible role in base excision repair.	Bebenek K	2001	The Journal of biological chemistry
5'-Deoxyribose phosphate lyase activity of human DNA polymerase iota in vitro.	Bebenek K	2001	Science
Proofreading of DNA polymerase eta-dependent replication errors.	Bebenek K	2001	The Journal of biological chemistry
Vertical-scanning mutagenesis of a critical tryptophan in the "minor groove binding track" of HIV-1 reverse transcriptase. Major groove DNA adducts identify specific protein interactions in the minor groove.	Bebenek K	2000	The Journal of biological chemistry
Human DNA polymerase kappa: a novel DNA polymerase of unknown biological function encoded by the DINB1 gene.	Bebenek K	2000	Cold Spring Harbor symposia on quantitative biology
Low fidelity DNA synthesis by human DNA polymerase-eta.	Bebenek K	2000	Nature
DNA replication fidelity.	Bebenek K	2000	Annual review of biochemistry
Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene.	Bebenek K	2000	The Journal of biological chemistry
Residues in the alphaH and alphaI helices of the HIV-1 reverse transcriptase thumb subdomain required for the specificity of RNase H-catalyzed removal of the polypurine tract primer.	Bebenek K	1999	The Journal of biological chemistry
Uniquely altered DNA replication fidelity conferred by an amino acid change in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase.	Bebenek K	1999	The Journal of biological chemistry
The base substitution fidelity of HIV-1 reverse transcriptase on DNA and RNA templates probed with 8-oxo-deoxyguanosine triphosphate.	Bebenek K	1999	Mutation research
Side chains that influence fidelity at the polymerase active site of Escherichia coli DNA polymerase I (Klenow fragment).	Bebenek K	1999	The Journal of biological chemistry
Vertical-scanning mutagenesis of a critical tryptophan in the minor groove binding track of HIV-1 reverse transcriptase. Molecular nature of polymerase-nucleic acid interactions.	Bebenek K	1998	The Journal of biological chemistry
A minor groove binding track in reverse transcriptase.	Bebenek K	1997	Nat Struct Biol
Probing structure/function relationships of HIV-1 reverse transcriptase with styrene oxide N2-guanine adducts.	Bebenek K	1997	The Journal of biological chemistry
Exonucleolytic proofreading during replication of repetitive DNA.	Bebenek K	1996	Biochemistry
Reduced frameshift fidelity and processivity of HIV-1 reverse transcriptase mutants containing alanine substitutions in helix H of the thumb subdomain.	Bebenek K	1995	The Journal of biological chemistry
Analyzing fidelity of DNA polymerases.	Bebenek K	1995	Methods in enzymology
Structure/function studies of human immunodeficiency virus type 1 reverse transcriptase. Alanine scanning mutagenesis of an alpha-helix in the thumb subdomain.	Bebenek K	1994	The Journal of biological chemistry
Error-prone polymerization by HIV-1 reverse transcriptase. Contribution of template-primer misalignment, miscoding, and termination probability to mutational hot spots.	Bebenek K	1993	The Journal of biological chemistry
Mechanism of HIV-1 reverse transcriptase. Termination of processive synthesis on a natural DNA template is influenced by the sequence of the template-primer stem.	Bebenek K	1993	The Journal of biological chemistry
Structure/function studies of HIV-1(1) reverse transcriptase: dimerization-defective mutant L289K.	Bebenek K	1993	Biochemistry
The effects of dNTP pool imbalances on frameshift fidelity during DNA replication.	Bebenek K	1992	The Journal of biological chemistry
Biochemical studies on the reverse transcriptase and RNase H activities from human immunodeficiency virus strains resistant to 3'-azido-3'-deoxythymidine.	Bebenek K	1992	The Journal of biological chemistry
Unequal human immunodeficiency virus type 1 reverse transcriptase error rates with RNA and DNA templates.	Bebenek K	1992	Proceedings of the National Academy of Sciences of the United States of America
Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme.	Bebenek K	1990	The Journal of biological chemistry
The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I.	Bebenek K	1990	The Journal of biological chemistry
Frameshift errors initiated by nucleotide misincorporation.	Bebenek K	1990	Proceedings of the National Academy of Sciences of the United States of America
The use of native T7 DNA polymerase for site-directed mutagenesis.	Bebenek K	1989	Nucleic acids research
Specificity and mechanism of error-prone replication by human immunodeficiency virus-1 reverse transcriptase.	Bebenek K	1989	The Journal of biological chemistry
The accuracy of reverse transcriptase from HIV-1.	Bebenek K	1988	Science (New York, N.Y.)

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Bebenek K

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