Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers.

Abstract:

Cyclobutane thymine dimers (T□T) comprise the majority of DNA damage ...

Polymerases:

Topics:

Kinetic Parameters, Nucleotide Analogs / Template Lesions, Fidelity, Accessory Proteins/Complexes, Nucleotide Incorporation, Exonuclease Activity, Enzyme Substrate Interactions, Methods, Source / Purification

Status:

new topics/pols set partial results complete validated

Results:

Polymerase Reference Property Result Context
Human Pol gamma D198AG200A Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers. 3-5' Exonuclease (proofreading) No
Human Pol gamma D198AG200A Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers. Cloned or native Insect cells
Human Pol gamma D198AG200A Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers. 5-3' Exonuclease Unspecified
Human Pol gamma D198AG200A Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers. Tagged Yes
Human Pol gamma D198AG200A Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers. Tag Name HIS
Human Pol gamma Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers. 3-5' Exonuclease (proofreading) Yes
Human Pol gamma Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers. Cloned or native Insect cells
Human Pol gamma Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers. Tagged Yes
Human Pol gamma Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers. Tag Name HIS
Human Pol gamma Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers. Full length or truncated Full length

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