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Sakaguchi K

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Publications:

Title Authors Year Journal
Differential requirement for the N-terminal catalytic domain of the DNA polymerase ε p255 subunit in the mitotic cell cycle and the endocycle. Sakaguchi K 2012 Gene
Characterization of marine X-family DNA polymerases and comparative analysis of base excision repair proteins. Sakaguchi K 2011 Biochemical and biophysical research communications
A sulfoglycolipid beta-sulfoquinovosyldiacylglycerol (betaSQDG) binds to Met1-Arg95 region of murine DNA polymerase lambda (Mmpol lambda) and inhibits its nuclear transit. Sakaguchi K 2010 Protein Eng Des Sel
Distribution and roles of X-family DNA polymerases in eukaryotes. Sakaguchi K 2009 Biochimie
Structure and activity relationship of monogalactosyl diacylglycerols, which selectively inhibited in vitro mammalian replicative DNA polymerase activity and human cancer cell growth. Sakaguchi K 2009 Cancer Lett
DNA polymerase mu interacts with a meiosis-specific RecA homolog Lim15 during meiosis in Coprinus cinereus. Sakaguchi K 2009 Biochem Biophys Res Commun
Characterization of plant XRCC1 and its interaction with proliferating cell nuclear antigen. Sakaguchi K 2008 Planta
Effect of dehydroaltenusin-C12 derivative, a selective DNA polymerase alpha inhibitor, on DNA replication in cultured cells. Sakaguchi K 2008 Molecules
The specific inhibitory effect of demethoxydehydroaltenusin, a derivative of dehydroaltenusin, on mammalian DNA polymerase alpha. Sakaguchi K 2008 Int J Mol Med
Chemical properties of fatty acid derivatives as inhibitors of DNA polymerases. Sakaguchi K 2007 Organic & biomolecular chemistry
Anti-tumor effects of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha. Sakaguchi K 2007 Biochem Biophys Res Commun
Biochemical properties of a plastidial DNA polymerase of rice. Sakaguchi K 2007 Plant Mol Biol
Synthetic analogues of the manzamenones and plakoridines which inhibit DNA polymerase. Sakaguchi K 2006 Bioorganic & medicinal chemistry letters
Site-directed mutational analysis of structural interactions of low molecule compounds binding to the N-terminal 8 kDa domain of DNA polymerase beta. Sakaguchi K 2006 Biochem Biophys Res Commun
Drosophila DNA polymerase zeta interacts with recombination repair protein 1, the Drosophila homologue of human abasic endonuclease 1. Sakaguchi K 2006 The Journal of biological chemistry
Structural relationship of curcumin derivatives binding to the BRCT domain of human DNA polymerase lambda. Sakaguchi K 2006 Genes Cells
Characterization of a second proliferating cell nuclear antigen (PCNA2) from Drosophila melanogaster. Sakaguchi K 2006 The FEBS journal
Inhibitory effect of tocotrienol on eukaryotic DNA polymerase lambda and angiogenesis. Sakaguchi K 2006 Biochem Biophys Res Commun
Beta-sitosterol-3-O-beta-D-glucopyranoside: a eukaryotic DNA polymerase lambda inhibitor. Sakaguchi K 2006 J Steroid Biochem Mol Biol
5-(Hydroxymethyl)-2-furfural: a selective inhibitor of DNA polymerase lambda and terminal deoxynucleotidyltransferase. Sakaguchi K 2006 Arch Biochem Biophys
Sulfoquinovosylmonoacylglycerol inhibitory mode analysis of rat DNA polymerase beta. Sakaguchi K 2005 FEBS J
Selective inhibitors of terminal deoxyribonucleotidyltransferase (TdT): baicalin and genistin. Sakaguchi K 2005 Biochimica et biophysica acta
Effects of DNA polymerase inhibitory and antitumor activities of lipase-hydrolyzed glycolipid fractions from spinach. Sakaguchi K 2005 J Nutr Biochem
Mammalian mitotic centromere-associated kinesin (MCAK): a new molecular target of sulfoquinovosylacylglycerols novel antitumor and immunosuppressive agents. Sakaguchi K 2005 The FEBS journal
Sulfo-quinovosyl-acyl-glycerol (SQAG), a eukaryotic DNA polymerase inhibitor and anti-cancer agent. Sakaguchi K 2005 Curr Med Chem Anticancer Agents
Monoacetylcurcumin: a new inhibitor of eukaryotic DNA polymerase lambda and a new ligand for inhibitor-affinity chromatography. Sakaguchi K 2005 Biochem Biophys Res Commun
Plastid DNA polymerases from higher plants, Arabidopsis thaliana. Sakaguchi K 2005 Biochemical and biophysical research communications
Effective form of sulfoquinovosyldiacyglycerol (SQDG) vesicles for DNA polymerase inhibition. Sakaguchi K 2005 Colloids Surf B Biointerfaces
Affinity capture of a mammalian DNA polymerase beta by inhibitors immobilized to resins used in solid-phase organic synthesis. Sakaguchi K 2005 Bioconjug Chem
Structural analysis of epolactaene derivatives as DNA polymerase inhibitors and anti-inflammatory compounds. Sakaguchi K 2005 Int J Mol Med
Dipeptide alcohol-based inhibitors of eukaryotic DNA polymerase alpha. Sakaguchi K 2005 Bioorg Med Chem
L-Homoserylaminoethanol, a novel dipeptide alcohol inhibitor of eukaryotic DNA polymerase from a plant cultured cells, Nicotina tabacum L. Sakaguchi K 2004 Bioorg Med Chem
Structure-activity relationships of epolactaene analogs as DNA polymerases inhibitors. Sakaguchi K 2004 Bioorganic & medicinal chemistry
A novel DNA topoisomerase inhibitor: dehydroebriconic acid, one of the lanostane-type triterpene acids from Poria cocos. Sakaguchi K 2004 Cancer science
Mechanism of cell cycle arrest by sulfoquinovosyl monoacylglycerol with a C18-saturated fatty acid (C18-SQMG). Sakaguchi K 2004 Biochemical pharmacology
Taxol derivatives are selective inhibitors of DNA polymerase alpha. Sakaguchi K 2004 Bioorg Med Chem
Plant DNA polymerase lambda, a DNA repair enzyme that functions in plant meristematic and meiotic tissues. Sakaguchi K 2004 Eur J Biochem
Structural relationship of lithocholic acid derivatives binding to the N-terminal 8-kDa domain of DNA polymerase beta. Sakaguchi K 2004 Biochemistry
Molecular design of cholesterols as inhibitors of DNA polymerase alpha. Sakaguchi K 2004 J Med Chem
The effects of dehydroaltenusin, a novel mammalian DNA polymerase alpha inhibitor, on cell proliferation and cell cycle progression. Sakaguchi K 2004 Biochimica et biophysica acta
Precise structural elucidation of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha. Sakaguchi K 2004 Bioorg Med Chem
Subunit protein-affinity isolation of Drosophila DNA polymerase catalytic subunit. Sakaguchi K 2004 Protein Expr Purif
Purification of Drosophila DNA polymerase zeta by REV1 protein-affinity chromatography. Sakaguchi K 2004 Biochem J
Some anti-chronic inflammatory compounds are DNA polymerase lambda-specific inhibitors. Sakaguchi K 2003 Biochem Pharmacol
A sulphoquinovosyl diacylglycerol is a DNA polymerase epsilon inhibitor. Sakaguchi K 2003 Biochem J
Selective inhibition of mammalian DNA polymerase alpha by vitamin D2 and D3. Sakaguchi K 2003 J Pharmacol Sci
Inhibition of DNA polymerases and DNA topoisomerase II by triterpenes produced by plant callus. Sakaguchi K 2003 Biochemical and biophysical research communications
Analysis of cell cycle regulation by 1-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride (SQMG), an inhibitor of eukaryotic DNA polymerases. Sakaguchi K 2003 Biochemical pharmacology
Dissociation of DNA polymerase alpha-primase complex during meiosis in Coprinus cinereus. Sakaguchi K 2003 Eur J Biochem
Flavonoid glycoside: a new inhibitor of eukaryotic DNA polymerase alpha and a new carrier for inhibitor-affinity chromatography. Sakaguchi K 2003 Biochem Biophys Res Commun
A novel DNA polymerase inhibitor and a potent apoptosis inducer: 2-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride with stearic acid. Sakaguchi K 2003 Biochimica et biophysica acta
Effects of glycolipids from spinach on mammalian DNA polymerases. Sakaguchi K 2003 Biochemical pharmacology
Molecular action mode of Hippospongic acid A, an inhibitor of gastrulation of starfish embryos. Sakaguchi K 2003 Journal of biochemistry
The inhibitory action of pyrrolidine alkaloid, 1,4-dideoxy-1,4-imino-D-ribitol, on eukaryotic DNA polymerases. Sakaguchi K 2003 Biochemical and biophysical research communications
Inhibitory action of emulsified sulfoquinovosyl acylglycerol on mammalian DNA polymerases. Sakaguchi K 2003 Lipids
Pyridoxal 5'-phosphate is a selective inhibitor in vivo of DNA polymerase alpha and epsilon. Sakaguchi K 2003 Biochem Biophys Res Commun
A novel DNA polymerase homologous to Escherichia coli DNA polymerase I from a higher plant, rice (Oryza sativa L.). Sakaguchi K 2002 Nucleic acids research
Three-dimensional structural model analysis of the binding site of an inhibitor, nervonic acid, of both DNA polymerase beta and HIV-1 reverse transcriptase. Sakaguchi K 2002 Journal of biochemistry
Novel anti-inflammatory compounds from Rubus sieboldii, triterpenoids, are inhibitors of mammalian DNA polymerases. Sakaguchi K 2002 Biochimica et biophysica acta
Vitamin A-related compounds, all-trans retinal and retinoic acids, selectively inhibit activities of mammalian replicative DNA polymerases. Sakaguchi K 2002 Biochimica et biophysica acta
Selective inhibition of the activities of both eukaryotic DNA polymerases and DNA topoisomerases by elenic acid. Sakaguchi K 2002 Biochemical pharmacology
Characterization of DNA polymerase delta from a higher plant, rice (Oryza sativa L.). Sakaguchi K 2002 Gene
Petasiphenol: a DNA polymerase lambda inhibitor. Sakaguchi K 2002 Biochemistry
Structure-function relationship of synthetic sulfoquinovosyl-acylglycerols as mammalian DNA polymerase inhibitors. Sakaguchi K 2002 Arch Biochem Biophys
[Structural homology between molecular probes binding site of DNA polymerase beta and DNA topoisomerase II]. Sakaguchi K 2002 Tanpakushitsu Kakusan Koso
Actions of derivatives of dehydroaltenusin, a new mammalian DNA polymerase alpha-specific inhibitor. Sakaguchi K 2002 Biochem Pharmacol
A plant phytotoxin, solanapyrone A, is an inhibitor of DNA polymerase beta and lambda. Sakaguchi K 2002 The Journal of biological chemistry
Three-dimensional structural model analysis of the binding site of lithocholic acid, an inhibitor of DNA polymerase beta and DNA topoisomerase II. Sakaguchi K 2001 J Biochem
Synthesis of sulfoquinovosylacylglycerols, inhibitors of eukaryotic DNA polymerase alpha and beta. Sakaguchi K 2001 Bioorg Med Chem
Specific interaction between an oligosaccharide on the tumor cell surface and the novel antitumor agents, sulfoquinovosylacylglycerols. Sakaguchi K 2001 Biochemical and biophysical research communications
Dehydroaltenusin, a mammalian DNA polymerase alpha inhibitor. Sakaguchi K 2000 The Journal of biological chemistry
Novel triterpenoids inhibit both DNA polymerase and DNA topoisomerase. Sakaguchi K 2000 Biochem J
Differentiation of rat pheochromocytoma cells by fomitellic acids, specific DNA polymerase inhibitors. Sakaguchi K 2000 Life Sci
Structure of lithocholic acid binding to the N-terminal 8-kDa domain of DNA polymerase beta. Sakaguchi K 2000 Biochemistry
Structure-activity relationship of a novel group of mammalian DNA polymerase inhibitors, synthetic sulfoquinovosylacylglycerols. Sakaguchi K 2000 Jpn J Cancer Res
Structural homology between DNA binding sites of DNA polymerase beta and DNA topoisomerase II. Sakaguchi K 2000 Journal of molecular biology
The biochemical mode of inhibition of DNA polymerase beta by alpha-rubromycin. Sakaguchi K 2000 Biochimica et biophysica acta
DNA polymerases and Ki-67 nuclear antigen are induced in correlation with the resected mass of rat liver up to 90%. Sakaguchi K 2000 Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie
Novel anti-inflammatory compounds from Myrsine seguinii, terpeno-benzoic acids, are inhibitors of mammalian DNA polymerases. Sakaguchi K 2000 Biochimica et biophysica acta
Epolactaene, a novel neuritogenic compound in human neuroblastoma cells, selectively inhibits the activities of mammalian DNA polymerases and human DNA topoisomerase II. Sakaguchi K 2000 Biochemical and biophysical research communications
Mode analysis of binding of fatty acids to mammalian DNA polymerases. Sakaguchi K 2000 Biochimica et biophysica acta
Molecular cloning and expression during development of the Drosophila gene for the catalytic subunit of DNA polymerase epsilon. Sakaguchi K 2000 Gene
Studies on a novel DNA polymerase inhibitor group, synthetic sulfoquinovosylacylglycerols: inhibitory action on cell proliferation. Sakaguchi K 2000 Mutation research
Lucidenic acid O and lactone, new terpene inhibitors of eukaryotic DNA polymerases from a basidiomycete, Ganoderma lucidum. Sakaguchi K 1999 Bioorganic & medicinal chemistry
Mode analysis of a fatty acid molecule binding to the N-terminal 8-kDa domain of DNA polymerase beta. A 1:1 complex and binding surface. Sakaguchi K 1999 The Journal of biological chemistry
The cyanogenic glucoside, prunasin (D-mandelonitrile-beta-D-glucoside), is a novel inhibitor of DNA polymerase beta. Sakaguchi K 1999 J Biochem
Action of a new mammalian DNA polymerase inhibitor, sulfoquinovosyldiacylglycerol. Sakaguchi K 1999 Biol Pharm Bull
A new DNA polymerase species from Drosophila melanogaster: a probable mus308 gene product. Sakaguchi K 1999 Mutation research
The biochemical inhibition mode of bredinin-5'-monophosphate on DNA polymerase beta. Sakaguchi K 1998 Biochimica et biophysica acta
Purification and characterization of a 100 kDa DNA polymerase from cauliflower inflorescence. Sakaguchi K 1998 Biochem J
An ergosterol peroxide, a natural product that selectively enhances the inhibitory effect of linoleic acid on DNA polymerase beta. Sakaguchi K 1998 Biol Pharm Bull
4-Hydroxy-17-methylincisterol, an inhibitor of DNA polymerase-alpha activity and the growth of human cancer cells in vitro. Sakaguchi K 1998 Biochemical pharmacology
A mushroom fruiting body-inducing substance inhibits activities of replicative DNA polymerases. Sakaguchi K 1998 Biochemical and biophysical research communications
Sulfoquinovosyldiacylglycerol, KM043, a new potent inhibitor of eukaryotic DNA polymerases and HIV-reverse transcriptase type 1 from a marine red alga, Gigartina tenella. Sakaguchi K 1998 Chemical & pharmaceutical bulletin
Studies on inhibitors of mammalian DNA polymerase alpha and beta: sulfolipids from a pteridophyte, Athyrium niponicum. Sakaguchi K 1998 Biochemical pharmacology
Fomitellic acids, triterpenoid inhibitors of eukaryotic DNA polymerases from a basidiomycete, Fomitella fraxinea. Sakaguchi K 1998 Journal of natural products
A 5'-monophosphate form of bredinin selectively inhibits the activities of mammalian DNA polymerases in vitro. Sakaguchi K 1998 International journal of molecular medicine
Carboxyflavins, novel inhibitors of Taq DNA polymerase. Sakaguchi K 1998 International journal of molecular medicine
The inhibitory effect of novel triterpenoid compounds, fomitellic acids, on DNA polymerase beta. Sakaguchi K 1998 Biochem J
The inhibitory action of fatty acids on DNA polymerase beta. Sakaguchi K 1997 Biochimica et biophysica acta
DNA polymerase epsilon from Drosophila melanogaster. Sakaguchi K 1997 Biochem Biophys Res Commun
A DNA polymerase alpha catalytic subunit is purified independently from the tissues at meiotic prometaphase I of a basidiomycete, Coprinus cinereus. Sakaguchi K 1997 Biochem Biophys Res Commun
Fatty acids selectively inhibit eukaryotic DNA polymerase activities in vitro. Sakaguchi K 1996 Biochimica et biophysica acta
Transcriptional regulation of the Drosophila CycA gene by the DNA replication-related element (DRE) and DRE binding factor (DREF). Sakaguchi K 1996 Nucleic acids research
A new meiotic protein factor which enhances activity of meiotic DNA polymerase from Coprinus cinereus. Sakaguchi K 1994 Biochem Biophys Res Commun
A meiotic DNA polymerase from a mushroom, Agaricus bisporus. Sakaguchi K 1994 Biochem J
Drosophila DNA polymerase delta. Purification and characterization. Sakaguchi K 1994 The Journal of biological chemistry
A meiotic DNA polymerase from Coprinus cinereus: further purification and characterization. Sakaguchi K 1993 Chromosoma
The influence of a protein synthesis inhibitor on sister-chromatid exchange in the plant Vicia faba. Sakaguchi K 1986 Mutation research
Purification and characterization of a DNA polymerase beta from Drosophila*. Sakaguchi K 1985 The Journal of biological chemistry
Meiosis in Coprinus: characterization and activities of two forms of DNA polymerase during meiotic stages. Sakaguchi K 1982 Molecular and cellular biology

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