The EMBO journal

(EMBO J) ISSNs: , 1460-2075

References in The EMBO journal:

Title Authors Year
Mechanisms of accurate translesion synthesis by human DNA polymerase eta. Masutani C, Kusumoto R, Iwai S, Hanaoka F 2000
SV40 T antigen binds directly to the large subunit of purified DNA polymerase alpha. Dornreiter I, Höss A, Arthur AK, Fanning E 1990
A mammalian DNA polymerase alpha holoenzyme functioning on defined in vivo-like templates. Hübscher U, Gerschwiler P, McMaster GK 1982
A mutant T7 RNA polymerase as a DNA polymerase. Sousa R, Padilla R 1995
Human immunodeficiency virus type 1 reverse transcriptase: role of Tyr115 in deoxynucleotide binding and misinsertion fidelity of DNA synthesis. Martín-Hernández AM, Domingo E, Menéndez-Arias L 1996
DNA polymerase II, the probable homolog of mammalian DNA polymerase epsilon, replicates chromosomal DNA in the yeast Saccharomyces cerevisiae. Araki H, Ropp PA, Johnson AL, Johnston LH, Morrison A, Sugino A 1992
The structure of HIV-1 reverse transcriptase complexed with an RNA pseudoknot inhibitor. Jaeger J, Restle T, Steitz TA 1998
Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4. Wong JH, Brown JA, Suo Z, Blum P, Nohmi T, Ling H 2010
DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period. Kimura H, Nozaki N, Sugimoto K 1994
Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme. Back NK, Nijhuis M, Keulen W, Boucher CA, Oude Essink BO, van Kuilenburg AB, van Gennip AH, Berkhout B 1996
Role of a dipeptide insertion between codons 69 and 70 of HIV-1 reverse transcriptase in the mechanism of AZT resistance. Mas A, Parera M, Briones C, Soriano V, Martínez MA, Domingo E, Menéndez-Arias L 2000
Reverse transcriptases and genomic variability: the accuracy of DNA replication is enzyme specific and sequence dependent. Ricchetti M, Buc H 1990
DNA polymerase epsilon, acetylases and remodellers cooperate to form a specialized chromatin structure at a tRNA insulator. Dhillon N, Raab J, Guzzo J, Szyjka SJ, Gangadharan S, Aparicio OM, Andrews B, Kamakaka RT 2009
Misinsertion and bypass of thymine-thymine dimers by human DNA polymerase iota. Tissier A, Frank EG, McDonald JP, Iwai S, Hanaoka F, Woodgate R 2000
The Oct-1 POU domain stimulates adenovirus DNA replication by a direct interaction between the viral precursor terminal protein-DNA polymerase complex and the POU homeodomain. Coenjaerts FE, van Oosterhout JA, van der Vliet PC 1994
Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA. Sarafianos SG, Das K, Tantillo C, Clark AD, Ding J, Whitcomb JM, Boyer PL, Hughes SH, Arnold E 2001
Lesion bypass in yeast cells: Pol eta participates in a multi-DNA polymerase process. Bresson A, Fuchs RP 2002
Resolution of head-on collisions between the transcription machinery and bacteriophage phi29 DNA polymerase is dependent on RNA polymerase translocation. Elías-Arnanz M, Salas M 1999
Essential interaction between the fission yeast DNA polymerase delta subunit Cdc27 and Pcn1 (PCNA) mediated through a C-terminal p21(Cip1)-like PCNA binding motif. Reynolds N, Warbrick E, Fantes PA, MacNeill SA 2000
Division of labor--sequential ATP hydrolysis drives assembly of a DNA polymerase sliding clamp around DNA. Hingorani MM, Bloom LB, Goodman MF, O'Donnell ME 1999
DNA polymerase beta is critical for mouse meiotic synapsis. Kidane D, Jonason AS, Gorton TS, Mihaylov I, Pan J, Keeney S, de Rooij DG, Ashley T, Keh A, Liu Y, Banerjee U, Zelterman D, Sweasy JB 2010
A novel assembly mechanism for the DNA polymerase III holoenzyme DnaX complex: association of deltadelta' with DnaX(4) forms DnaX(3)deltadelta'. Pritchard AE, Dallmann HG, Glover BP, McHenry CS 2000
Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase. Pellicioli A, Lucca C, Liberi G, Marini F, Lopes M, Plevani P, Romano A, Di Fiore PP, Foiani M 1999
Accuracy of DNA polymerase-alpha in copying natural DNA. Grosse F, Krauss G, Knill-Jones JW, Fersht AR 1983
DNA polymerase epsilon may be dispensable for SV40- but not cellular-DNA replication. Zlotkin T, Kaufmann G, Jiang Y, Lee MY, Uitto L, Syväoja J, Dornreiter I, Fanning E, Nethanel T 1996
Structure of the SSB-DNA polymerase III interface and its role in DNA replication. Marceau AH, Bahng S, Massoni SC, George NP, Sandler SJ, Marians KJ, Keck JL 2011
The internal workings of a DNA polymerase clamp-loading machine. Turner J, Hingorani MM, Kelman Z, O'Donnell ME 1999
The fission yeast Cdc1 protein, a homologue of the small subunit of DNA polymerase delta, binds to Pol3 and Cdc27. MacNeill SA, Moreno S, Reynolds N, Nurse P, Fantes PA 1996
The 3' to 5' exonuclease activity located in the DNA polymerase delta subunit of Saccharomyces cerevisiae is required for accurate replication. Simon M, Giot L, Faye G 1991
High-efficiency bypass of DNA damage by human DNA polymerase Q. Seki M, Masutani C, Yang LW, Schuffert A, Iwai S, Bahar I, Wood RD 2004
Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity. Masutani C, Araki M, Yamada A, Kusumoto R, Nogimori T, Maekawa T, Iwai S, Hanaoka F 1999
Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein. Wang JY, Ling H, Yang WW, Craigie R 2001
Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination. Watanabe K, Tateishi S, Kawasuji M, Tsurimoto T, Inoue H, Yamaizumi M 2004
Replication slippage involves DNA polymerase pausing and dissociation. Viguera E, Canceill D, Ehrlich SD 2001
A role for DNA polymerase alpha in epigenetic control of transcriptional silencing in fission yeast. Nakayama Ji , Allshire RC, Klar AJ, Grewal SI 2001
Devoted to the lagging strand-the subunit of DNA polymerase III holoenzyme contacts SSB to promote processive elongation and sliding clamp assembly. Kelman Z, Yuzhakov A, Andjelkovic J, O'Donnell ME 1998
Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein. Kubota Y, Nash RA, Klungland A, Schär P, Barnes DE, Lindahl T 1996
Human DNA polymerase beta initiates DNA synthesis during long-patch repair of reduced AP sites in DNA. Podlutsky AJ, Dianova II, Podust VN, Bohr VA, Dianov GL 2001
Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase Cdk. Mimura S, Takisawa H 1998
Replication through an abasic DNA lesion: structural basis for adenine selectivity. Obeid S, Blatter N, Kranaster R, Schnur A, Diederichs K, Welte W, Marx A 2010
Proofreading dynamics of a processive DNA polymerase. Ibarra B, Chemla YR, Plyasunov S, Smith SB, Lázaro JM, Salas M, Bustamante C 2009
Subunit-selective mutagenesis indicates minimal polymerase activity in heterodimer-associated p51 HIV-1 reverse transcriptase. Le Grice SF, Naas T, Wohlgensinger B, Schatz O 1991
Human immunodeficiency virus type 1 reverse transcriptase tG:T mispair formation on RNA and DNA templates with mismatched primers: a kinetic and thermodynamic study. Sala M, Wain-Hobson S, Schaeffer F 1995
Mutations in T7 RNA polymerase that support the proposal for a common polymerase active site structure. Bonner G, Patra D, Lafer EM, Sousa R 1992
A novel function of DNA polymerase zeta regulated by PCNA. Northam MR, Garg P, Baitin DM, Burgers PM, Shcherbakova PV 2006
Neonatal lethality with abnormal neurogenesis in mice deficient in DNA polymerase beta. Sugo N, Aratani Y, Nagashima Y, Kubota Y, Koyama H 2000
Plasmid rolling circle replication: identification of the RNA polymerase-directed primer RNA and requirement for DNA polymerase I for lagging strand synthesis. Kramer MG, Khan SA, Espinosa M 1997
The EM structure of human DNA polymerase gamma reveals a localized contact between the catalytic and accessory subunits. Yakubovskaya E, Lukin M, Chen Z, Berriman J, Wall JS, Kobayashi R, Kisker C, Bogenhagen DF 2007
The mammalian primase is part of a high molecular weight DNA polymerase alpha polypeptide. Hübscher U 1983
Structure and function of the Saccharomyces cerevisiae CDC2 gene encoding the large subunit of DNA polymerase III. Boulet A, Simon M, Faye G, Bauer GA, Burgers PM 1989
DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1. Cobb JA, Bjergbaek L, Shimada K, Frei C, Gasser SM 2003
A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome. Gambus A, van Deursen F, Polychronopoulos D, Foltman M, Jones RC, Edmondson RD, Calzada A, Labib K 2009
Human DNA polymerase iota protects cells against oxidative stress. Petta TB, Nakajima S, Zlatanou A, Despras E, Couve-Privat S, Ishchenko A, Sarasin A, Yasui A, Kannouche PL 2008
DNA polymerase beta is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extracts. Allinson SL, Dianova II, Dianov GL 2001
Multiple competition reactions for RPA order the assembly of the DNA polymerase delta holoenzyme. Yuzhakov A, Kelman Z, Hurwitz J, O'Donnell ME 1999
Evidence for a Cdc6p-independent mitotic resetting event involving DNA polymerase alpha. Desdouets C, Santocanale C, Drury LS, Perkins G, Foiani M, Plevani P, Diffley JF 1998
The role of the 70 kDa subunit of human DNA polymerase alpha in DNA replication. Collins KL, Russo AA, Tseng BY, Kelly TJ 1993
Recognition of the adenovirus type 2 origin of DNA replication by the virally encoded DNA polymerase and preterminal proteins. Temperley SM, Hay RT 1992
Crystal structure of mammalian poly(A) polymerase in complex with an analog of ATP. Martin G, Keller W, Doublié S 2000
Mutations in human DNA polymerase eta motif II alter bypass of DNA lesions. Glick E, Vigna KL, Loeb LA 2001
A novel type of replicative enzyme harbouring ATPase, primase and DNA polymerase activity. Lipps G, Röther S, Hart C, Krauss G 2003
HIV-1 reverse transcriptase-associated RNase H cleaves RNA/RNA in arrested complexes: implications for the mechanism by which RNase H discriminates between RNA/RNA and RNA/DNA. Götte M, Fackler S, Hermann T, Perola E, Cellai L, Gross HJ, Le Grice SF, Heumann H 1995
Bacteriophage phi29 DNA replication arrest caused by codirectional collisions with the transcription machinery. Elías-Arnanz M, Salas M 1997
Dysregulation of DNA polymerase κ recruitment to replication forks results in genomic instability. Jones MJ, Colnaghi L, Huang TT 2012
Bypass specialists operate together. Takata Kei-ichi, Wood RichardD 2009
Cell cycle-dependent dynamic association of cyclin/Cdk complexes with human DNA replication proteins. Frouin I, Montecucco A, Biamonti G, Hübscher U, Spadari S, Maga G 2002
Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals. Shachar S, Ziv O, Avkin S, Adar S, Wittschieben JP, Reissner T, Chaney S, Friedberg EC, Wang Z, Carell T, Geacintov NE, Livneh Z 2009
A role for p53 in base excision repair. Zhou J, Ahn J, Wilson SH, Prives C 2001
Visualizing polynucleotide polymerase machines at work. Steitz TA 2006
Compartmentalization of phage phi29 DNA replication: interaction between the primer terminal protein and the membrane-associated protein p1. Bravo A, Illana B, Salas M 2000
A DNA binding motif coordinating synthesis and degradation in proofreading DNA polymerases. Truniger V, Lázaro JM, Salas M, Blanco L 1996
Competitive processivity-clamp usage by DNA polymerases during DNA replication and repair. López de Saro FJ, Georgescu RE, Goodman MF, O'Donnell ME 2003
Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells. Kannouche PL, Fernández de Henestrosa AR, Coull B, Vidal AE, Gray C, Zicha D, Woodgate R, Lehmann AR 2003
Unique misinsertion specificity of poliota may decrease the mutagenic potential of deaminated cytosines. Vaisman A, Woodgate R 2001
Subunit-specific degradation of the UmuD/D' heterodimer by the ClpXP protease: the role of trans recognition in UmuD' stability. Gonzalez M, Rasulova F, Maurizi MR, Woodgate R 2000
The large subunit of replication factor C is a substrate for caspase-3 in vitro and is cleaved by a caspase-3-like protease during Fas-mediated apoptosis. Rhéaume E, Cohen LY, Uhlmann F, Lazure C, Alam A, Hurwitz J, Sékaly RP, Denis F 1997
Structural and functional relationships between prokaryotic and eukaryotic DNA polymerases. Bernad A, Zaballos A, Salas M, Blanco L 1987
Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells. Kannouche PL, Fernández de Henestrosa AR, Coull B, Vidal AE, Gray C, Zicha D, Woodgate R, Lehmann AR 2002
Altered nucleotide misinsertion fidelity associated with poliota-dependent replication at the end of a DNA template. Frank EG, Tissier A, McDonald JP, Rapić-Otrin V, Zeng X, Gearhart PJ, Woodgate R 2001
Regulation of DNA replication and repair proteins through interaction with the front side of proliferating cell nuclear antigen. Jónsson ZO, Hindges R, Hübscher U 1998
Tyrosine 114 is essential for the trimeric structure and the functional activities of human proliferating cell nuclear antigen. Jónsson ZO, Podust VN, Podust LM, Hübscher U 1995
DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation. Bétous R, Pillaire MJ, Pierini L, van der Laan S, Recolin B, Ohl-Séguy E, Guo C, Niimi N, Grúz P, Nohmi T, Friedberg EC, Cazaux C, Maiorano D, Hoffmann JS 2013
Mechanism of polymerase collision release from sliding clamps on the lagging strand. Georgescu RE, Kurth I, Yao NY, Stewart J, Yurieva O, O'Donnell ME 2009
Structural basis for recruitment of translesion DNA polymerase Pol IV/DinB to the beta-clamp. Bunting KA, Roe SM, Pearl LH 2003
Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA. Sarafianos SG, Clark AD, Das K, Tuske S, Birktoft JJ, Ilankumaran P, Ramesha AR, Sayer JM, Jerina DM, Boyer PL, Hughes SH, Arnold E 2002
3D architecture of DNA Pol alpha reveals the functional core of multi-subunit replicative polymerases. Klinge S, Núñez-Ramírez R, Llorca O, Pellegrini L 2009
Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation. Li Y, Korolev S, Waksman G 1998
Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerases. Wong SW, Wahl AF, Yuan PM, Arai N, Pearson BE, Arai K, Korn D, Hunkapiller MW, Wang TS 1988
Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis. Vaisman A, Ling H, Woodgate R, Yang WW 2005
Lesion (in)tolerance reveals insights into DNA replication fidelity. Freisinger E, Grollman AP, Miller H, Kisker C 2004
Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. Brieba LG, Eichman BF, Kokoska RJ, Doublié S, Kunkel TA, Ellenberger T 2004
Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism. Beese LS, Steitz TA 1991
Site-directed mutagenesis at the Exo III motif of phi 29 DNA polymerase; overlapping structural domains for the 3'-5' exonuclease and strand-displacement activities. Soengas MS, Esteban JA, Lázaro JM, Bernad A, Blasco MA, Salas M, Blanco L 1992
Crystallographic snapshots of a replicative DNA polymerase encountering an abasic site. Hogg M, Wallace SS, Doublié S 2004
DNA polymerase mu (Pol mu), homologous to TdT, could act as a DNA mutator in eukaryotic cells. Domínguez O, Ruiz JF, Laín de Lera T, García-Díaz M, González MA, Kirchhoff T, Martínez-A C, Bernad A, Blanco L 2000
Primer-terminus stabilization at the 3'-5' exonuclease active site of phi29 DNA polymerase. Involvement of two amino acid residues highly conserved in proofreading DNA polymerases. de Vega M, Lazaro JM, Salas M, Blanco L 1996
The 3'-5' exonuclease of DNA polymerase I of Escherichia coli: contribution of each amino acid at the active site to the reaction. Derbyshire V, Grindley ND, Joyce CM 1991
The phi29 DNA polymerase:protein-primer structure suggests a model for the initiation to elongation transition. Kamtekar S, Berman AJ, Wang J, Lázaro JM, de Vega M, Blanco L, Salas M, Steitz TA 2006
Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases. Berman AJ, Kamtekar S, Goodman JL, Lázaro JM, de Vega M, Blanco L, Salas M, Steitz TA 2007
Protein-primed DNA replication: a transition between two modes of priming by a unique DNA polymerase. Mendez J, Blanco L, Salas M 1997
Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase iota. Kirouac KN, Ling H 2009
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