Eco Pol I*

From E. coli
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Welcome to the Polymerase Page

This page presents all the information in Polbase for Eco Pol I*.

Mutants:

At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.

Structures/Sequence:

If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.

References:

All references that refer to this Polymerase are listed with their topics and paper's title in the References table.

Results:

All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

Eco Pol I* is a family A enzyme from E. coli.

Selected Properties for Eco Pol I*:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
Yes (1) Yes (1) no data no data no data
Year Authors Title Results by property
2013 Christopher H Corzett, Myron F Goodman, Steven E Finkel Competitive Fitness during Feast and ...
2011 Kinrin Yamanaka, Irina G Minko, Steven E Finkel, Myron F Goodman, R Stephen Lloyd Role of high-fidelity Escherichia col...
2009 Qingfei Jiang, Kiyonobu Karata, Roger Woodgate, Michael M Cox, Myron F Goodman The active form of DNA polymerase V i...
2009 Karolina Makiela-Dzbenska, Malgorzata Jaszczur, Magdalena Banach-Orlowska, Piotr Jonczyk, Roel M Schaaper, I Fijalkowska Role of Escherichia coli DNA polymera...
2008 Anuradha Kumari, Irina G Minko, Michael B Harbut, Steven E Finkel, Myron F Goodman, R Stephen Lloyd Replication bypass of interstrand cro...
2008 Kaori Uchida, Asako Furukohri, Yutaka Shinozaki, Tetsuya Mori, Daichi Ogawara, Shigehiko Kanaya, Takehiko Nohmi, Hisaji Maki, Masahiro Tatsumi Akiyama Overproduction of Escherichia coli DN...
2007 Stephen G Anderson, Christopher R Williams, Mike E O'Donnell, Linda B Bloom A function for the psi subunit in loa...
2006 Linda B Bloom Dynamics of loading the Escherichia c...
2005 Eric R Goedken, Steven L Kazmirski, Gregory D Bowman, Mike E O'Donnell, John Kuriyan Mapping the interaction of DNA with t...
2005 Anna K Chikova, Roel M Schaaper The bacteriophage P1 hot gene product...
2004 Eugene F DeRose, Thomas W Kirby, Geoffrey A Mueller, Anna K Chikova, Roel M Schaaper, Robert E London Phage like it HOT: solution structure...
2004 Jacqueline M Gulbis, Steven L Kazmirski, Jeff Finkelstein, Zvi Kelman, Mike E O'Donnell, John Kuriyan Crystal structure of the chi:psi sub-...
2004 Steven L Kazmirski, Marjetka Podobnik, Tanya F Weitze, Mike E O'Donnell, John Kuriyan Structural analysis of the inactive s...
2003 Molly Chiaramonte, Chad L Moore, Kristi Kincaid, Robert D Kuchta Facile polymerization of dNTPs bearin...
2003 Karen A Bunting, S Mark Roe, Laurence H Pearl Structural basis for recruitment of t...
2003 Olga Kornyushyna, Cynthia J Burrows Effect of the oxidized guanosine lesi...
2002 Naomi Suzuki, Eiji Ohashi, Alexander Kolbanovskiy, Nicholas E Geacintov, Arthur P Grollman, Haruo Ohmori, Shinya Shibutani Translesion synthesis by human DNA po...
2002 Rajiv Gangurde, Mukund J Modak Participation of active-site carboxyl...
2001 Naomi Suzuki, Eiji Ohashi, Kiyoshi Hayashi, Haruo Ohmori, Arthur P Grollman, Shinya Shibutani Translesional synthesis past acetylam...
2001 Jaya K Kumar, R Kremsdorf, Stanley Tabor, Charles C Richardson A Mutation in the gene-encoding bacte...
2000 Irina Bruck, Mike E O'Donnell The DNA replication machine of a gram...
2000 T V Rao, M T Haber, Jane M Sayer, Donald M Jerina Incorporation of 4-thiothymidine into...
2000 Rajiv Gangurde, Neerja Kaushik, Kamalendra Singh, Mukund J Modak A carboxylate triad is essential for ...
1999 D Canceill, Enrique Viguera, S Dusko Ehrlich Replication slippage of different DNA...
1999 Jérôme E Wagner, Petr Grúz, Su-Ryang Kim, Masami Yamada, Keiko Matsui, Robert P P Fuchs, Takehiko Nohmi The dinB gene encodes a novel E. coli...
1999 Dana T Minnick, Katarzyna Bebenek, Wendy P Osheroff, Robert M Turner, Mekbib Astatke, Lingfeng Liu, Thomas A Kunkel, Catherine M Joyce Side chains that influence fidelity a...
1999 C A Clairmont, L Narayanan, Ka-Wai Sun, Peter M Glazer, Joann B Sweasy The Tyr-265-to-Cys mutator mutant of ...
1998 Olga I Lavrik, Heinz Peter Nasheuer, Klaus Weisshart, M S Wold, Rajendra Prasad, William A Beard, Samuel H Wilson, Alain Favre Subunits of human replication protein...
1998 Verónica Truniger, José María Lázaro, Margarita Salas, Luis Blanco Phi 29 DNA polymerase requires the N-...
1998 M J Guo, S Hildbrand, C J Leumann, L W McLaughlin, M J Waring Inhibition of DNA polymerase reaction...
1998 Yoshiyuki Mizushina, T Ueno, Y Goto, Y Isobe, M Sako, T Fujita, Kouji Hirota, H Hayashi, Kengo Sakaguchi Carboxyflavins, novel inhibitors of T...
1997 T Kogoma, R R Maldonado DNA polymerase I in constitutive stab...
1995 M N Rigler, Louis J Romano Differences in the mechanism of stimu...
1995 Hiroyuki Kamiya, Hironori Kasai Formation of 2-hydroxydeoxyadenosine ...
1995 Joann B Sweasy, M Chen, Lawrence A Loeb DNA polymerase beta can substitute fo...
1995 Patricia L Foster, G Gudmundsson, J M Trimarchi, H Cai, Myron F Goodman Proofreading-defective DNA polymerase...
1995 Stanley Tabor, Charles C Richardson A single residue in DNA polymerases o...
1994 P N Yadav, J S Yadav, Edward Arnold, Mukund J Modak A computer-assisted analysis of conse...
1994 Yoshizumi Ishino, Hiroshi Iwasaki, Ikunoshin Kato, Hideo Shinagawa Amino acid sequence motifs essential ...
1993 V Derbyshire, Mekbib Astatke, Catherine M Joyce Re-engineering the polymerase domain ...
1993 B Liu, M L Wong, R L Tinker, E P Geiduschek, B M Alberts The DNA replication fork can pass RNA...
1993 Kristin A Eckert, Thomas A Kunkel Fidelity of DNA synthesis catalyzed b...
1993 W C Brown, Judith L Campbell Interaction of proliferating cell nuc...
1993 P D Gutman, K W Minton Conserved sites in the 5'-3' exonucle...
1992 S Sankar, A G Porter Point mutations which drastically aff...
1992 Catherine M Joyce, Xiaojun Chen Sun, Nigel D F Grindley Reactions at the polymerase active si...
1992 Daekyu Sun, Laurence H Hurley Effect of the (+)-CC-1065-(N3-adenine...
1992 Luis Blanco, Antonio Bernad, Margarita Salas Evidence favouring the hypothesis of ...
1991 M A Blasco, Antonio Bernad, Luis Blanco, Margarita Salas Characterization and mapping of the p...
1990 G A Nevinskiĭ, I A Potapova, N B Tarusova, O V Khalabuda, V V Khomov [Interaction of dNTP-binding sites of...
1990 Linda J Reha-Krantz Genetic evidence for two protein doma...
1990 I A Potapova, G A Nevinsky, V V Khomov, Olga I Lavrik NaF and mononucleotides as inhibitors...
1990 Vladimir N Podust, T O Korobeinicheva, G A Nevinsky, A S Levina, Olga I Lavrik Inactivation of DNA polymerase by ade...
1990 T Ohnishi, S Yuba, T Date, H Utsumi, Akio Matsukage Rat DNA polymerase beta gene can join...
1989 T A Rozovskaia, Sh Kh Minasian, M K Kukhanova, A A Kraevskiĭ, Z G Chidzhavadze [DNA polymerase I, Klenow fragment of...
1988 E K Spicer, J Rush, C Fung, Linda J Reha-Krantz, Jim D Karam, William H Konigsberg Primary structure of T4 DNA polymeras...
1988 P Keohavong, A G Kat, N F Cariello, William G Thilly DNA amplification in vitro using T4 D...
1988 T Date, Masamitsu Yamaguchi, Fumiko Hirose, Y Nishimoto, K Tanihara, Akio Matsukage Expression of active rat DNA polymera...
1988 C A Bonner, S K Randall, C Rayssiguier, Miroslav Radman, R Eritja, B E Kaplan, K McEntee, Myron F Goodman Purification and characterization of ...
1988 Hisaji Maki, Satoko Maki, Arthur Kornberg DNA Polymerase III holoenzyme of Esch...
1988 H M Lim, J J Pène Optimal conditions for supercoil DNA ...
1987 H E Huber, Stanley Tabor, Charles C Richardson Escherichia coli thioredoxin stabiliz...
1987 Ulrich Hübscher, M Gassmann, Silvio Spadari, Neal C Brown, Elena Ferrari, H J Buhk Mammalian DNA polymerase alpha: a rep...
1987 S B Zimmerman, B Harrison Macromolecular crowding increases bin...
1987 Juhani E Syväoja ATP-stimulated polymerase activity in...
1987 Hisaji Maki, Arthur Kornberg Proofreading by DNA polymerase III of...
1986 M S Johnson, M A McClure, D F Feng, J Gray, R F Doolittle Computer analysis of retroviral pol g...
1985 D Lackey, S W Krauss, Stuart Linn Characterization of DNA polymerase I*... Cloned or native,Full length or truncated,Processivity,3-5' exo,5-3' exo,All properties
1984 A K Hazra, S Detera-Wadleigh, Samuel H Wilson Site-specific modification of Escheri...
1983 R L Lechner, M J Engler, Charles C Richardson Characterization of strand displaceme...
1981 O Niwa, Robb E Moses Synthesis by DNA polymerase I on bleo...
1981 Ulrich Hübscher, A Spanos, W Albert, F Grummt, G R Banks Evidence that a high molecular weight...
1981 C Upton, R J Pinney Absence of ultraviolet-inducible DNA ...
1978 Peter M J Burgers, F Eckstein Absolute configuration of the diaster...
1978 R D Ley, B A Sedita, E Boye DNA polymerase I-mediated repair of 3...
1978 M Włodarczyk, M Bednarska Replication of plasmid R6K in DNA pol...
1977 R Vicuna, Jerard Hurwitz, S Wallace, M Girard Selective inhibition of in vitro DNA ...
1976 E R Fluck, L A Poirier, H W Ruelius Evaluation of a DNA polymerase-defici...
1975 P Modrich, Charles C Richardson Bacteriophage T7 deoxyribonucleic aci...
1974 Jerard Hurwitz, S Wickner Involvement of two protein factors an...
1973 Jerard Hurwitz, S Wickner, M Wright Studies on in vitro DNA synthesis. II...
1971 Lawrence A Loeb, J P Slater, J L Ewald, S S Agarwal In vitro DNA synthesis in the presenc...
1971 Arthur Kornberg [Recent studies on the active center ...
1970 Robb E Moses, Charles C Richardson A new DNA polymerase activity of Esch...
1970 H Klenow, I Henningsen Selective elimination of the exonucle...
1970 Robb E Moses, Charles C Richardson A new DNA polymerase acitvity of Esch...
1969 L Toji, S S Cohen The enzymatic termination of polydeox...
1968 Paul T Englund, M P Deutscher, T M Jovin, R B Kelly, N R Cozzarelli, Arthur Kornberg Structural and functional properties ...
1968 R P Klett, A Cerami, E Reich Exonuclease VI, a new nuclease activi...
1968 CD Steuart, SR Anand, MJ Bessman Studies on the synthesis of deoxyribo...
1964 Charles C Richardson, C L SCHILDKRAUT, H V APOSHIAN, Arthur Kornberg ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLE...
1962 H V APOSHIAN, Arthur Kornberg Enzymatic synthesis of deoxyribonucle...
1958 M J Bessman, I. Robert Lehman, J Adler, S B Zimmerman, E S Simms, Arthur Kornberg ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLE... Incorporation of non-standard nucleotides,All properties

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