Human Pol kappa

From H. sapiens (aliases:DINB) (genes: POLK)
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Welcome to the Polymerase Page

This page presents all the information in Polbase for Human Pol kappa.

Mutants:

At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.

Structures/Sequence:

If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.

External links:

Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.

References:

All references that refer to this Polymerase are listed with their topics and paper's title in the References table.

Results:

All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

Human Pol kappa is a family Y enzyme from H. sapiens.

Selected Properties for Human Pol kappa:

3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
No (3) no data 1.8e-03 errors/bp (1) 5.8e-03-6.6e-03 errors/bp (3) no data
Year Authors Title Results by property
S Sharma, CM Helchowski, CE Canman Sharma S
2014 Akira Sassa, Tetsuya Suzuki, Yuki Kanemaru, Naoko Niimi, Hirofumi Fujimoto, Atsushi Katafuchi, Petr Grúz, Manabu Yasui, Ramesh C Gupta, Francis Johnson, Toshihiro Ohta, Masamitsu Honma, Noritaka Adachi, Takehiko Nohmi Sassa A2014
2013 Leena Maddukuri, Sarah C Shuck, Robert Lawton Eoff, Linlin Zhao, Carmelo J Rizzo, F Peter Guengerich, Lawrence J Marnett Maddukuri L2013 Template lesions,All properties
2013 DJ Taggart, Terry L Camerlengo, Jason K Harrison, Shanen M Sherrer, Ajay K Kshetry, John-Stephen Taylor, Kun Huang, Zucai Suo Taggart DJ2013
2013 Yoshiyuki Mizushina, Isoko Kuriyama, Tatsuo Nakahara, Yoshihito Kawashima, Hiromi Yoshida Mizushina Y2013
2013 Amit Ketkar, Maroof Khan Zafar, Leena Maddukuri, Kinrin Yamanaka, Surajit Banerjee, Martin Egli, Jeong-Yun Choi, R Stephen Lloyd, Robert Lawton Eoff Ketkar A2013
2012 Huifang Zhu, Yanfeng Fan, Jing Shen, Hongyan Qi, Jimin Shao Zhu H2012
2012 Kinrin Yamanaka, Dorjbal Dorjsuren, Robert Lawton Eoff, Martin Egli, David J Maloney, Ajit Jadhav, Anton Simeonov, R Stephen Lloyd Yamanaka K2012
2012 Shanen M Sherrer, Laura E Sanman, Cynthia X Xia, Eric R Bolin, Chanchal K Malik, Georgia Efthimiopoulos, Ashis K Basu, Zucai Suo Sherrer SM2012
2012 Mathew Jk Jones, Luca Colnaghi, Tony T Huang Jones MJ2012
2012 Jundong Zhou, Shuyu Zhang, Ling Xie, Pengfei Liu, Fang Xie, Jinchang Wu, Jianping Cao, Wei-Qun Ding Zhou J2012
2012 Shanen M Sherrer, DJ Taggart, Lindsey R Pack, Chanchal K Malik, Ashis K Basu, Zucai Suo Sherrer SM2012
2011 Matthew G Pence, Patrick Blans, Charles N Zink, James C Fishbein, Fred W Perrino Pence MG2011
2011 Akira Sassa, Naoko Niimi, Hirofumi Fujimoto, Atsushi Katafuchi, Petr Grúz, Manabu Yasui, Ramesh C Gupta, Francis Johnson, Toshihiro Ohta, Takehiko Nohmi Sassa A2011
2011 Rodrigo Vasquez-Del Carpio, Timothy D Silverstein, Samer Lone, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Vasquez-Del Carpio R2011
2010 Mark D Sutton Sutton MD2010
2009 Asami Hishiki, Hiroshi Hashimoto, Tomo Hanafusa, Keijiro Kamei, Eiji Ohashi, Toshiyuki Shimizu, Haruo Ohmori, Mamoru Sato Hishiki A2009
2009 Rodrigo Vasquez-Del Carpio, Timothy D Silverstein, Samer Lone, Michael K Swan, Jayati Roy Choudhury, Robert E Johnson, Satya Prakash, Louise Prakash, Aneel K Aggarwal Vasquez-Del Carpio R2009
2009 Adriana Irimia, Robert Lawton Eoff, F Peter Guengerich, Martin Egli Irimia A2009
2009 Rémy Bétous, Laurie Rey, Guliang Wang, Marie-Jeanne Pillaire, Nadine Puget, Janick Selves, Denis S F Biard, Kazuo Shin-ya, Karen M Vasquez, Christophe Cazaux, Jean-Sébastien Hoffmann Bétous R2009
2009 Naoko Niimi, Akira Sassa, Atsushi Katafuchi, Petr Grúz, Hirofumi Fujimoto, Radha-Rani Bonala, Francis Johnson, Toshihiro Ohta, Takehiko Nohmi Niimi N2009
2009 Dorjbal Dorjsuren, David M Wilson, William A Beard, John P McDonald, Christopher P Austin, Roger Woodgate, Samuel H Wilson, Anton Simeonov Dorjsuren D2009
2009 Haijiang Zhang, Jeff W Beckman, F Peter Guengerich Zhang H2009
2008 Scott D McCulloch, Thomas A Kunkel McCulloch SD2008 Frameshift Error Rate,Nucleotide Substitution Rate,All properties
2008 Lei Jia, Nicholas E Geacintov, Suse Broyde Jia L2008
2008 Linda J Reha-Krantz Reha-Krantz LJ2008
2007 Samer Lone, Sharon A Townson, Sacha N Uljon, Robert E Johnson, Amrita Brahma, Deepak T Nair, Satya Prakash, Louise Prakash, Aneel K Aggarwal Lone S2007
2007 Wei Wen Yang, Roger Woodgate Yang WW2007
2007 Adam P Silverman, Qingfei Jiang, Myron F Goodman, Eric T Kool Silverman AP2007
2006 Chiu Hong Lee, Sushil Chandani, Edward L Loechler Lee CH2006
2006 William T Wolfle, Robert E Johnson, Irina G Minko, R Stephen Lloyd, Satya Prakash, Louise Prakash Wolfle WT2006
2006 Karissa D Carlson, Robert E Johnson, Louise Prakash, Satya Prakash, M Todd Washington Carlson KD2006
2006 Jeong-Yun Choi, Goutam Chowdhury, Hong Zang, Karen C Angel, Choua C Vu, Lisa A Peterson, F Peter Guengerich Choi JY2006
2006 Jeong-Yun Choi, James S Stover, Karen C Angel, Goutam Chowdhury, Carmelo J Rizzo, F Peter Guengerich Choi JY2006
2006 Jeong-Yun Choi, Karen C Angel, F Peter Guengerich Choi JY2006
2005 Wei Wen Yang Yang WW2005
2005 Clarisse Bavoux, Andréia Machado Leopoldino, Valérie Bergoglio, Jiyang O-Wang, Tomoo Ogi, Anne Bieth, Jean-Gabriel Judde, Sérgio Danilo Junho Pena, Marie-France Poupon, Thomas Helleday, Masatoshi Tagawa, Carlosrenato Machado, Jean-Sébastien Hoffmann, Christophe Cazaux Bavoux C2005
2005 William T Wolfle, Robert E Johnson, Irina G Minko, R Stephen Lloyd, Satya Prakash, Louise Prakash Wolfle WT2005
2005 Satya Prakash, Robert E Johnson, Louise Prakash Prakash S2005
2005 William T Wolfle, M Todd Washington, Eric T Kool, Thomas E Spratt, Sandra A Helquist, Louise Prakash, Satya Prakash Wolfle WT2005
2004 Naomi Suzuki, Manabu Yasui, Y R Santosh Laxmi, Haruo Ohmori, Fumio Hanaoka, Shinya Shibutani Suzuki N2004
2004 Sacha N Uljon, Robert E Johnson, Thomas A Edwards, Satya Prakash, Louise Prakash, Aneel K Aggarwal Uljon SN2004
2004 Naomi Suzuki, Shinji Itoh, Kinning Poon, Chikahide Masutani, Fumio Hanaoka, Haruo Ohmori, Itsuo Yoshizawa, Shinya Shibutani Suzuki N2004
2004 M Todd Washington, Irina G Minko, Robert E Johnson, William T Wolfle, Thomas M Harris, R Stephen Lloyd, Satya Prakash, Louise Prakash Washington MT2004
2003 Thomas A Kunkel, Youri I Pavlov, Katarzyna Bebenek Kunkel TA2003 Full length or truncated,3-5' exo,Nucleotide Substitution Rate,All properties
2003 William T Wolfle, M Todd Washington, Louise Prakash, Satya Prakash Wolfle WT2003
2002 Lajos Haracska, Ildiko Unk, Robert E Johnson, Barbara B Phillips, Jerard Hurwitz, Louise Prakash, Satya Prakash Haracska L2002
2002 Yongqing Zhang, Xiaoming Wu, Dongyu Guo, Olga Rechkoblit, Nicholas E Geacintov, Zhengqiang Wang Zhang Y2002
2002 Tomoo Ogi, Yoichi Shinkai, Kiyoji Tanaka, Haruo Ohmori Ogi T2002
2002 Ulrich Hubscher, Giovanni Maga, Silvio Spadari Hubscher U2002
2002 Valérie Bergoglio, Clarisse Bavoux, Vincent Verbiest, Jean-Sébastien Hoffmann, Christophe Cazaux Bergoglio V2002
2002 Paula L Fischhaber, Valerie L Gerlach, William J Feaver, Zafer Hatahet, Susan S Wallace, Errol C Friedberg Fischhaber PL2002
2002 Yongqing Zhang, Xiaoming Wu, Dongyu Guo, Olga Rechkoblit, Zhengqiang Wang Zhang Y2002
2002 Lajos Haracska, Louise Prakash, Satya Prakash Haracska L2002
2002 Naomi Suzuki, Eiji Ohashi, Alexander Kolbanovskiy, Nicholas E Geacintov, Arthur P Grollman, Haruo Ohmori, Shinya Shibutani Suzuki N2002
2001 Naomi Suzuki, Eiji Ohashi, Kiyoshi Hayashi, Haruo Ohmori, Arthur P Grollman, Shinya Shibutani Suzuki N2001
2001 Valerie L Gerlach, William J Feaver, Paula L Fischhaber, Errol C Friedberg Gerlach VL2001 Cloned or native,Tagged,Tag Name,Full length or truncated,Processivity,3-5' exo,Template lesions,All properties
2000 Yongqing Zhang, Fenghua Yuan, Xiaoming Wu, Michael Wang, Olga Rechkoblit, John-Stephen Taylor, Nicholas E Geacintov, Zhengqiang Wang Zhang Y2000
2000 Yongqing Zhang, Fenghua Yuan, Hongkui Xin, Xiaoming Wu, D K Rajpal, D Yang, Zhengqiang Wang Zhang Y2000
2000 Valerie L Gerlach, William J Feaver, Paula L Fischhaber, James A Richardson, L Aravind, Eugene V Koonin, Katarzyna Bebenek, Thomas A Kunkel, Errol C Friedberg Gerlach VL2000
2000 Eiji Ohashi, Katarzyna Bebenek, Toshiro Matsuda, William J Feaver, Valerie L Gerlach, Errol C Friedberg, Haruo Ohmori, Thomas A Kunkel Ohashi E2000 Cloned or native,Tagged,Tag Name,Full length or truncated,Processivity,Gap fill,3-5' exo,Nucleotide Substitution Rate,All properties
2000 Eiji Ohashi, Tomoo Ogi, Rika Kusumoto, Shigenori Iwai, Chikahide Masutani, Fumio Hanaoka, Haruo Ohmori Ohashi E2000
Protein sequence:
DNA sequence:
Name 3'-5' exo activity 5'-3' exo activity Frameshift Rate Substitution Rate General Error Rate
Pol Kappa F171A
Pol Kappa (exo-) No (1) 7.4e-03 errors/bp (1)
All Polymerases | 21 Results

Using Polbase tables:

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