Eco Pol III
From
E. coli
(aliases:Pol III)
Welcome to the Polymerase Page
This page presents all the information in Polbase for Eco Pol III.
Mutants:At the top of the page you'll find a map of all positions of known mutants. Text links to mutants and digestion products are listed in the Mutants section.
Structures/Sequence:If available, a representative structure is displayed at the upper right. All known structures are listed in the Structures section.
External links:Polbase polymerases are linked to UniProt and Genbank where possible. The UniProt search link directs you to a pre-constructed UniProt search containing relevant terms.
References:All references that refer to this Polymerase are listed with their topics and paper's title in the References table.
Results:All the results for this polymerase can be examined by following the "Results" link at the bottom of the page.
Help icons:
The symbol in the upper-right corner of the page
links to this help text. The question mark icon is used everywhere to indicate that help is available.
Eco Pol III
is a family C enzyme
from
E. coli.
Selected Properties for Eco Pol III: |
3'-5' exo activity | 5'-3' exo activity | Frameshift Rate | Substitution Rate | General Error Rate |
|---|---|---|---|---|---|
| Yes (4) | No (1) | 5.0e-09-1.4e-06 errors/bp (2) | 8.0e-08-3.8e-06 errors/bp (2) | 8.1e-04-9.8e-04 errors/bp (2) |
- References (222)
- Structures (28)
- Sequences (1)
- Mutants (1)...
- Formulations (0)
- Polymerase Lots (0)
- External links
| Year | Authors | Title | Results by property |
|---|---|---|---|
| 2013 | Christopher H Corzett, Myron F Goodman, Steven E Finkel | Competitive Fitness during Feast and ... | |
| 2013 | Kiyoshi Ozawa, NP Horan, A Robinson, H Yagi, FR Hill, Slobodan Jergic, ZQ Xu, KV Loscha, N Li, M Tehei, Aaron J Oakley, Gottfried Otting, T Huber, Nicholas E Dixon | Proofreading exonuclease on a tether:... | |
| 2013 | Tiago Barros, Joel Guenther, Brian A Kelch, Jordan Anaya, Arjun Prabhakar, Mike E O'Donnell, John Kuriyan, Meindert H Lamers | A structural role for the PHP domain ... | |
| 2013 | Chiara Indiani, Meghna Patel, Myron F Goodman, Mike E O'Donnell | RecA acts as a switch to regulate pol... | |
| 2012 | Masami Yamada, Masatomi Shimizu, Atsushi Katafuchi, Petr Grúz, Shingo Fujii, Yukio Usui, Robert P P Fuchs, Takehiko Nohmi | Escherichia coli DNA polymerase III i... | |
| 2012 | MC Silva, P Nevin, EA Ronayne, PJ Beuning | Selective disruption of the DNA polym... | |
| 2012 | Emanuele Conte, Gabriele Vincelli, Roel M Schaaper, Daniela Bressanin, Alessandra Stefan, Fabrizio Dal Piaz, Alejandro Hochkoeppler | Stabilization of the Escherichia coli... | |
| 2011 | Natalie Naue, Roman Fedorov, Andreas Pich, Dietmar J Manstein, Ute Curth | Site-directed mutagenesis of the χ su... | |
| 2011 | Shi-Qiang Lin, Li-Jun Bi, Xian-En Zhang | A simplified method for reconstitutin... | |
| 2011 | Kinrin Yamanaka, Irina G Minko, Steven E Finkel, Myron F Goodman, R Stephen Lloyd | Role of high-fidelity Escherichia col... | |
| 2011 | Paul R Dohrmann, Carol M Manhart, Christopher D Downey, Charles S McHenry | The Rate of Polymerase Release upon F... | Strand Displacement,All properties |
| 2011 | Christopher D Downey, Elliott Crooke, Charles S McHenry | Polymerase Chaperoning and Multiple A... | |
| 2011 | Sho T Yano, Lucia B Rothman-Denes | A phage-encoded inhibitor of Escheric... | |
| 2011 | Charles S McHenry | Breaking the rules: bacteria that use... | |
| 2011 | Jing Fang, John R Engen, Penny J Beuning | Escherichia coli processivity clamp β... | |
| 2010 | Ah Young Park, Slobodan Jergic, Argyris Politis, Brandon T Ruotolo, Daniel Hirshberg, Linda L Jessop, Jennifer L Beck, Daniel Barsky, Mike E O'Donnell, Nicholas E Dixon, Carol V Robinson | A single subunit directs the assembly... | |
| 2010 | Anna Wieczorek, Christopher D Downey, H Garry Dallmann, Charles S McHenry | Only one ATP-binding DnaX subunit is ... | |
| 2010 | Mark D Sutton | Coordinating DNA polymerase traffic d... | |
| 2010 | Linda J Reha-Krantz | DNA polymerase proofreading: Multiple... | |
| 2010 | Ken Hirano, Yuichiro Yoshida, Tomomi Ishido, Yukihisa Wada, Naoji Moriya, Naoshi Yamazaki, Yoshiyuki Mizushina, Yoshinobu Baba, Mitsuru Ishikawa | Consecutive incorporation of fluoroph... | |
| 2009 | Jennifer A Thompson, Christopher O Paschall, Mike E O'Donnell, Linda B Bloom | A slow ATP-induced conformational cha... | |
| 2009 | Karolina Makiela-Dzbenska, Malgorzata Jaszczur, Magdalena Banach-Orlowska, Piotr Jonczyk, Roel M Schaaper, I Fijalkowska | Role of Escherichia coli DNA polymera... | |
| 2009 | Justin M H Heltzel, Robert W Maul, Sarah K Scouten Ponticelli, Mark D Sutton | A model for DNA polymerase switching ... | |
| 2009 | Roxana E Georgescu, Isabel Kurth, Nina Y Yao, Jelena Stewart, Olga Yurieva, Mike E O'Donnell | Mechanism of polymerase collision rel... | |
| 2009 | Anna Pluciennik, Vickers Burdett, Olga Lukianova, Mike E O'Donnell, Paul Modrich | Involvement of the beta clamp in meth... | |
| 2009 | Daniela Bressanin, Alessandra Stefan, Fabrizio Dal Piaz, Stefano Cianchetta, Luca Reggiani, Alejandro Hochkoeppler | Proteolysis of the proofreading subun... | |
| 2009 | Justin M H Heltzel, Sarah K Scouten Ponticelli, Laurie H Sanders, Jill M Duzen, Vivian Cody, James Pace, Edward H Snell, Mark D Sutton | Sliding clamp-DNA interactions are re... | |
| 2009 | G Andrés Cisneros, Lalith Perera, Roel M Schaaper, Lars C Pedersen, Robert E London, Lee G Pedersen, Thomas A Darden | Reaction mechanism of the epsilon sub... | |
| 2008 | Linda J Reha-Krantz | Recent patents of gene sequences rela... | |
| 2008 | Asako Furukohri, Myron F Goodman, Hisaji Maki | A dynamic polymerase exchange with Es... | |
| 2008 | Roxana E Georgescu, Olga Yurieva, Seung-Sup Kim, John Kuriyan, Xiang-Peng Kong, Mike E O'Donnell | Structure of a small-molecule inhibit... | |
| 2008 | Kaori Uchida, Asako Furukohri, Yutaka Shinozaki, Tetsuya Mori, Daichi Ogawara, Shigehiko Kanaya, Takehiko Nohmi, Hisaji Maki, Masahiro Tatsumi Akiyama | Overproduction of Escherichia coli DN... | |
| 2008 | Kiyoshi Ozawa, Slobodan Jergic, Ah Young Park, Nicholas E Dixon, Gottfried Otting | The proofreading exonuclease subunit ... | |
| 2008 | Roxana E Georgescu, Seung-Sup Kim, Olga Yurieva, John Kuriyan, Xiang-Peng Kong, Mike E O'Donnell | Structure of a sliding clamp on DNA. | |
| 2008 | Micah J McCauley, Leila Shokri, Jana Sefcikova, Ceslovas Venclovas, Penny J Beuning, Mark C Williams | Distinct double- and single-stranded ... | |
| 2008 | Feng Li, Qin Liu, Yuan-Yuan Chen, Zi-Niu Yu, Zhi-Ping Zhang, Ya-Feng Zhou, Jiao-Yu Deng, Li-Jun Bi, Xian-En Zhang | Escherichia coli mismatch repair prot... | |
| 2007 | Xun-Cheng Su, Slobodan Jergic, Max A Keniry, Nicholas E Dixon, Gottfried Otting | Solution structure of Domains IVa and... | |
| 2007 | Slobodan Jergic, Kiyoshi Ozawa, Neal K Williams, Xun-Cheng Su, Daniel D Scott, Samir M Hamdan, Jeffrey A Crowther, Gottfried Otting, Nicholas E Dixon | The unstructured C-terminus of the ta... | |
| 2007 | Alessandra Stefan, Martin Tabler, Alejandro Hochkoeppler | Efficient silencing of the gene codin... | |
| 2007 | Peter McInerney, Mike E O'Donnell | Replisome fate upon encountering a le... | |
| 2007 | Fusamitsu Yanagihara, Shonen Yoshida, Yutaka Sugaya, Hisaji Maki | The dnaE173 mutator mutation confers ... | |
| 2006 | Thomas W Kirby, Scott Harvey, Eugene F DeRose, Sergey Chalov, Anna K Chikova, Fred W Perrino, Roel M Schaaper, Robert E London, Lars C Pedersen | Structure of the Escherichia coli DNA... | |
| 2006 | Meindert H Lamers, Roxana E Georgescu, Sang-Gyu Lee, Mike E O'Donnell, John Kuriyan | Crystal structure of the catalytic al... | |
| 2006 | Max A Keniry, Ah Young Park, Elisabeth A Owen, Samir M Hamdan, Guido Pintacuda, Gottfried Otting, Nicholas E Dixon | Structure of the theta subunit of Esc... | |
| 2005 | Anna K Chikova, Roel M Schaaper | The bacteriophage P1 hot gene product... | |
| 2005 | Thale C Jarvis, Amber A Beaudry, James M Bullard, Nebojsa Janjic, Charles S McHenry | Reconstitution of a minimal DNA repli... | |
| 2005 | Thale C Jarvis, Amber A Beaudry, James M Bullard, Urs Ochsner, H Garry Dallmann, Charles S McHenry | Discovery and characterization of the... | |
| 2005 | Geoffrey A Mueller, Thomas W Kirby, Eugene F DeRose, Dawei Li, Roel M Schaaper, Robert E London | Nuclear magnetic resonance solution s... | |
| 2004 | Duane A Lehtinen, Fred W Perrino | Dysfunctional proofreading in the Esc... | |
| 2004 | Steven L Kazmirski, Marjetka Podobnik, Tanya F Weitze, Mike E O'Donnell, John Kuriyan | Structural analysis of the inactive s... | |
| 2004 | Eugene F DeRose, Thomas W Kirby, Geoffrey A Mueller, Anna K Chikova, Roel M Schaaper, Robert E London | Phage like it HOT: solution structure... | |
| 2004 | Christopher R Williams, Anita K Snyder, Petr Kuzmic, Mike E O'Donnell, Linda B Bloom | Mechanism of loading the Escherichia ... | |
| 2004 | Francisco López de Saro, Roxana E Georgescu, Frank Leu, Mike E O'Donnell | Protein trafficking on sliding clamps. | |
| 2004 | Rajesh Gupta, Samir M Hamdan, Nicholas E Dixon, Margaret M Sheil, Jennifer L Beck | Application of electrospray ionizatio... | |
| 2004 | Anita K Snyder, Christopher R Williams, Aaron Johnson, Mike E O'Donnell, Linda B Bloom | Mechanism of loading the Escherichia ... | |
| 2004 | Jacqueline M Gulbis, Steven L Kazmirski, Jeff Finkelstein, Zvi Kelman, Mike E O'Donnell, John Kuriyan | Crystal structure of the chi:psi sub-... | |
| 2004 | Sharon A Taft-Benz, Roel M Schaaper | The theta subunit of Escherichia coli... | |
| 2004 | Gene Wijffels, Brian P Dalrymple, Pavel Prosselkov, Kritaya Kongsuwan, V Chandana Epa, Penelope E Lilley, Slobodan Jergic, Jens Buchardt, Susan E Brown, Paul F Alewood, Philip A Jennings, Nicholas E Dixon | Inhibition of protein interactions wi... | |
| 2003 | Marjetka Podobnik, Tanya F Weitze, Mike E O'Donnell, John Kuriyan | Nucleotide-induced conformational cha... | |
| 2003 | Francisco J López de Saro, Roxana E Georgescu, Myron F Goodman, Mike E O'Donnell | Competitive processivity-clamp usage ... | |
| 2003 | Charles S McHenry | Chromosomal replicases as asymmetric ... | |
| 2003 | Enrique Viguera, Mirjana Petranovic, Davor Zahradka, Karine Germain, Dusko S Ehrlich, Bénédicte Michel | Lethality of bypass polymerases in Es... | |
| 2003 | Brandon Ason, Renita Handayani, Christopher R Williams, Jeffrey G Bertram, Manju M Hingorani, Mike E O'Donnell, Myron F Goodman, Linda B Bloom | Mechanism of loading the Escherichia ... | |
| 2003 | Aaron J Oakley, Pavel Prosselkov, Gene Wijffels, Jennifer L Beck, Matthew C J Wilce, Nicholas E Dixon | Flexibility revealed by the 1.85 A cr... | |
| 2003 | Chiara Indiani, Mike E O'Donnell | Mechanism of the delta wrench in open... | |
| 2002 | Samir M Hamdan, Paul D Carr, Susan E Brown, David L Ollis, Nicholas E Dixon | Structural basis for proofreading dur... | |
| 2002 | Toshinari Onogi, Katsufumi Ohsumi, Tsutomu Katayama, Sota Hiraga | Replication-dependent recruitment of ... | |
| 2002 | Abu Amar M Al Mamun, Kenneth J Marians, M Zafri Humayun | DNA polymerase III from Escherichia c... | |
| 2002 | Angela Borden, Paul I O'Grady, Dominique Vandewiele, Antonio R Fernández de Henestrosa, Christopher W Lawrence, Roger Woodgate | Escherichia coli DNA polymerase III c... | |
| 2002 | Gianfranco Grompone, Marie Seigneur, S Dusko Ehrlich, Bénédicte Michel | Replication fork reversal in DNA poly... | |
| 2002 | Samir M Hamdan, Esther M Bulloch, Phillip R Thompson, Jennifer L Beck, Ji Yeon Yang, Jeffrey A Crowther, Penelope E Lilley, Paul D Carr, David L Ollis, Susan E Brown, Nicholas E Dixon | Hydrolysis of the 5'-p-nitrophenyl es... | |
| 2002 | Eugene F DeRose, Dawei Li, Thomas A Darden, Scott Harvey, Fred W Perrino, Roel M Schaaper, Robert E London | Model for the catalytic domain of the... | |
| 2002 | Dominique Vandewiele, Antonio R Fernández de Henestrosa, Andrew R Timms, Bryn A Bridges, Roger Woodgate | Sequence analysis and phenotypes of f... | |
| 2002 | Yutaka Sugaya, Keiichi Ihara, Yuji Masuda, Eiichi Ohtsubo, Hisaji Maki | Hyper-processive and slower DNA chain... | |
| 2001 | Jelena Stewart, Manju M Hingorani, Zvi Kelman, Mike E O'Donnell | Mechanism of beta clamp opening by th... | |
| 2001 | David Jeruzalmi, Olga Yurieva, Yaofeng Zhao, M Young, Jelena Stewart, M Hingorani, Mike E O'Donnell, John Kuriyan | Mechanism of processivity clamp openi... | |
| 2001 | F P Leu, Mike E O'Donnell | Interplay of clamp loader subunits in... | |
| 2001 | David Jeruzalmi, Mike E O'Donnell, John Kuriyan | Crystal structure of the processivity... | |
| 2001 | Mike E O'Donnell, David Jeruzalmi, John Kuriyan | Clamp loader structure predicts the a... | |
| 2001 | D Gao, Charles S McHenry | tau binds and organizes Escherichia c... | |
| 2000 | Irina Bruck, Mike E O'Donnell | The DNA replication machine of a gram... | |
| 2000 | Jeffrey G Bertram, Linda B Bloom, Manju M Hingorani, J M Beechem, Mike E O'Donnell, Myron F Goodman | Molecular mechanism and energetics of... | |
| 2000 | Samir M Hamdan, Susan E Brown, Phillip R Thompson, Ji Yeon Yang, Paul D Carr, David L Ollis, Gottfried Otting, Nicholas E Dixon | Preliminary X-ray crystallographic an... | |
| 2000 | Ayelet Maor-Shoshani, N B Reuven, Guy Tomer, Zvi Livneh | Highly mutagenic replication by DNA p... | Frameshift Error Rate,Nucleotide Substitution Rate,Overall Error Rate,All properties |
| 2000 | Brandon Ason, Jeffrey G Bertram, Manju M Hingorani, J M Beechem, Mike E O'Donnell, Myron F Goodman, Linda B Bloom | A model for Escherichia coli DNA poly... | |
| 2000 | Max A Keniry, H A Berthon, Ji Yeon Yang, C S Miles, Nicholas E Dixon | NMR solution structure of the theta s... | |
| 2000 | J R Walker, C Hervas, J D Ross, A Blinkova, M J Walbridge, E J Pumarega, M O Park, H R Neely | Escherichia coli DNA polymerase III t... | |
| 2000 | Arthur E Pritchard, H Garry Dallmann, Bradley P Glover, Charles S McHenry | A novel assembly mechanism for the DN... | |
| 2000 | Hiroyuki Kamiya, Hironori Kasai | 2-Hydroxy-dATP is incorporated opposi... | |
| 2000 | N Klemperer, D Zhang, Maija Skangalis, Mike E O'Donnell | Cross-utilization of the beta sliding... | |
| 1999 | Fred W Perrino, Scott Harvey, S M McNeill | Two functional domains of the epsilon... | |
| 1999 | N B Reuven, Gali Arad, Ayelet Maor-Shoshani, Zvi Livneh | The mutagenesis protein UmuC is a DNA... | |
| 1999 | L Fang, Megan J Davey, Mike E O'Donnell | Replisome assembly at oriC, the repli... | |
| 1999 | M Tang, Xuan Shen, Ekaterina G Frank, Mike E O'Donnell, Roger Woodgate, Myron F Goodman | UmuD'(2)C is an error-prone DNA polym... | |
| 1999 | D Canceill, Enrique Viguera, S Dusko Ehrlich | Replication slippage of different DNA... | |
| 1999 | Li Fan, P C Sanschagrin, Laurie S Kaguni, L A Kuhn | The accessory subunit of mtDNA polyme... | |
| 1999 | P T Pham, M W Olson, Charles S McHenry, Roel M Schaaper | Mismatch extension by Escherichia col... | |
| 1999 | Guy Tomer, Zvi Livneh | Analysis of unassisted translesion re... | |
| 1999 | Masayuki Seki, Masahiro Tatsumi Akiyama, Yutaka Sugaya, Eiichi Ohtsubo, Hisaji Maki | Strand asymmetry of +1 frameshift mut... | |
| 1998 | P T Pham, M W Olson, Charles S McHenry, Roel M Schaaper | The base substitution and frameshift ... | Cloned or native,Tagged,Full length or truncated,Specific Activity,3-5' exo,Frameshift Error Rate,Nucleotide Substitution Rate,All properties |
| 1998 | Piotr Jonczyk, A Nowicka, I J Fijałkowska, Roel M Schaaper, Z Cieśla | In vivo protein interactions within t... | |
| 1998 | Zvi Kelman, Alexander Yuzhakov, J Andjelkovic, Mike E O'Donnell | Devoted to the lagging strand-the sub... | |
| 1998 | Jeffrey G Bertram, Linda B Bloom, J Turner, Mike E O'Donnell, J M Beechem, Myron F Goodman | Pre-steady state analysis of the asse... | |
| 1997 | A G McNees, Mike E O'Donnell, P H Horton, H Y Kim, S J Kim, C M Harris, Thomas M Harris, R Stephen Lloyd | Lack of correlation between in vitro ... | |
| 1997 | B Guenther, R Onrust, A Sali, Mike E O'Donnell, John Kuriyan | Crystal structure of the delta' subun... | |
| 1997 | D R Kim, Arthur E Pritchard, Charles S McHenry | Localization of the active site of th... | |
| 1997 | Linda B Bloom, Xinbin Chen, D K Fygenson, J Turner, Mike E O'Donnell, Myron F Goodman | Fidelity of Escherichia coli DNA poly... | 3-5' exo,All properties |
| 1996 | J Y Mo, Roel M Schaaper | Fidelity and error specificity of the... | |
| 1996 | T Paz-Elizur, R Skaliter, S Blumenstein, Zvi Livneh | Beta*, a UV-inducible smaller form of... | |
| 1996 | D Canceill, S Dusko Ehrlich | Copy-choice recombination mediated by... | |
| 1996 | F B Perler, Sandeep Kumar, H Kong | Thermostable DNA polymerases. | Full length or truncated,3-5' exo,5-3' exo,Molecular Weight,All properties |
| 1996 | M Seville, A B West, M G Cull, Charles S McHenry | Fluorometric assay for DNA polymerase... | |
| 1996 | R Skaliter, M Bergstein, Zvi Livneh | Beta*, a UV-inducible shorter form of... | |
| 1996 | D R Kim, Charles S McHenry | Identification of the beta-binding do... | |
| 1996 | R Skaliter, T Paz-Elizur, Zvi Livneh | A smaller form of the sliding clamp s... | |
| 1996 | B J Lannutti, J Persinger, B Bartholomew | Probing the protein-DNA contacts of a... | |
| 1995 | J A Reems, S Wood, Charles S McHenry | Escherichia coli DNA polymerase III h... | |
| 1995 | H Garry Dallmann, R L Thimmig, Charles S McHenry | DnaX complex of Escherichia coli DNA ... | |
| 1995 | R Onrust, Jeff Finkelstein, V Naktinis, J Turner, L Fang, Mike E O'Donnell | Assembly of a chromosomal replication... | |
| 1995 | P T Stukenberg, Mike E O'Donnell | Assembly of a chromosomal replication... | |
| 1995 | J Turner, Mike E O'Donnell | Cycling of Escherichia coli DNA polym... | |
| 1995 | Sangbumn Kim, K J Marians | DNA and RNA-DNA annealing activity as... | |
| 1995 | M Hase, T Mizushima, T Katayama, K Sekimizu | Isolation and characterization of inh... | |
| 1995 | H Garry Dallmann, Charles S McHenry | DnaX complex of Escherichia coli DNA ... | |
| 1995 | M W Olson, H Garry Dallmann, Charles S McHenry | DnaX complex of Escherichia coli DNA ... | |
| 1995 | M G Cull, Charles S McHenry | Purification of Escherichia coli DNA ... | |
| 1995 | Patricia L Foster, G Gudmundsson, J M Trimarchi, H Cai, Myron F Goodman | Proofreading-defective DNA polymerase... | |
| 1994 | S C Slater, M R Lifsics, Mike E O'Donnell, R Maurer | holE, the gene coding for the theta s... | |
| 1994 | Y Tadmor, M Bergstein, R Skaliter, H Shwartz, Zvi Livneh | Beta subunit of DNA polymerase III ho... | |
| 1994 | Mike E O'Donnell | Beta sliding clamp dynamics within E.... | |
| 1994 | J A Reems, Charles S McHenry | Escherichia coli DNA polymerase III h... | |
| 1993 | J R Carter, M A Franden, R Aebersold, Charles S McHenry | Identification, isolation, and charac... | |
| 1993 | A Blinkova, C Hervas, P T Stukenberg, R Onrust, M E O'Donnell, J R Walker | The Escherichia coli DNA polymerase I... | |
| 1993 | H Xiao, R Crombie, Z Dong, R Onrust, Mike E O'Donnell | DNA polymerase III accessory proteins... | |
| 1993 | J R Carter, M A Franden, J A Lippincott, Charles S McHenry | Identification, molecular cloning and... | |
| 1993 | John Kuriyan, Mike E O'Donnell | Sliding clamps of DNA polymerases. | |
| 1992 | Patricia L Foster, M G Marinus | Levels of epsilon, an essential repli... | |
| 1992 | DNA Replication | ||
| 1992 | L G Fradkin, Arthur Kornberg | Prereplicative complexes of component... | |
| 1992 | Xiang-Peng Kong, R Onrust, Mike E O'Donnell, John Kuriyan | Three-dimensional structure of the be... | |
| 1992 | C A Wu, E L Zechner, A J Hughes, M A Franden, Charles S McHenry, K J Marians | Coordinated leading- and lagging-stra... | |
| 1992 | Mike E O'Donnell | Accessory protein function in the DNA... | |
| 1992 | C A Bonner, P T Stukenberg, M Rajagopalan, R Eritja, Mike E O'Donnell, K McEntee, H Echols, Myron F Goodman | Processive DNA synthesis by DNA polym... | Full length or truncated,Processivity,3-5' exo,Nucleotide incorporation accessory protein(s),All properties |
| 1992 | Luis Blanco, Antonio Bernad, Margarita Salas | Evidence favouring the hypothesis of ... | |
| 1992 | J R Carter, M A Franden, R Aebersold, Charles S McHenry | Molecular cloning, sequencing, and ov... | |
| 1991 | S Brenowitz, S Kwack, Myron F Goodman, Mike E O'Donnell, H Echols | Specificity and enzymatic mechanism o... | |
| 1991 | J A Reems, Mark A Griep, Charles S McHenry | Proofreading activity of DNA polymera... | |
| 1991 | A J Hughes, S K Bryan, H Chen, Robb E Moses, Charles S McHenry | Escherichia coli DNA polymerase II is... | |
| 1991 | P T Stukenberg, P S Studwell-Vaughan, Mike E O'Donnell | Mechanism of the sliding beta-clamp o... | |
| 1990 | M Carraway, C Rewinski, M G Marinus | Mutations produced by DNA polymerase ... | |
| 1990 | Mark A Griep, J A Reems, M A Franden, Charles S McHenry | Reduction of the potent DNA polymeras... | |
| 1990 | A M Flower, Charles S McHenry | The gamma subunit of DNA polymerase I... | |
| 1990 | Z Tsuchihashi, Arthur Kornberg | Translational frameshifting generates... | |
| 1989 | K C Sitney, Martin E Budd, Judith L Campbell | DNA polymerase III, a second essentia... | |
| 1989 | Fred W Perrino, Lawrence A Loeb | Proofreading by the epsilon subunit o... | |
| 1989 | H Shwartz, Zvi Livneh | RecA protein inhibits in vitro replic... | |
| 1989 | O Shavitt, Zvi Livneh | The beta subunit modulates bypass and... | |
| 1989 | Z Tsuchihashi, Arthur Kornberg | ATP interactions of the tau and gamma... | |
| 1989 | A Morrison, R B Christensen, J Alley, A K Beck, E G Bernstine, J F Lemontt, Christopher W Lawrence | REV3, a Saccharomyces cerevisiae gene... | |
| 1988 | Satoko Maki, Arthur Kornberg | DNA polymerase III holoenzyme of Esch... | |
| 1988 | Mark A Griep, Charles S McHenry | The dimer of the beta subunit of Esch... | |
| 1988 | G S Goetz, T Schmidt-Glenewinkel, M H Hu, N Belgado, Jerard Hurwitz | Studies on the role of the phi X174 g... | |
| 1988 | G S Goetz, Jerard Hurwitz | Studies on the role of the phi X174 g... | |
| 1988 | Charles S McHenry | DNA polymerase III holoenzyme of Esch... | |
| 1988 | Hisaji Maki, Satoko Maki, Arthur Kornberg | DNA Polymerase III holoenzyme of Esch... | |
| 1988 | D L Sloane, Myron F Goodman, H Echols | The fidelity of base selection by the... | |
| 1988 | M A Franden, Charles S McHenry | Detection of an epitope, not required... | |
| 1988 | N Tsurushita, Hisaji Maki, L J Korn | Site-directed mutagenesis with Escher... | |
| 1988 | Satoko Maki, Arthur Kornberg | DNA polymerase III holoenzyme of Esch... | |
| 1988 | Satoko Maki, Arthur Kornberg | DNA polymerase III holoenzyme of Esch... | |
| 1988 | Piotr Jonczyk, I Fijalkowska, Z Ciesla | Overproduction of the epsilon subunit... | |
| 1988 | C A Bonner, S K Randall, C Rayssiguier, Miroslav Radman, R Eritja, B E Kaplan, K McEntee, Myron F Goodman | Purification and characterization of ... | |
| 1987 | Ulrich Hübscher, M Gassmann, Silvio Spadari, Neal C Brown, Elena Ferrari, H J Buhk | Mammalian DNA polymerase alpha: a rep... | |
| 1987 | R S Lasken, Arthur Kornberg | The beta subunit dissociates readily ... | |
| 1987 | M E Hagensee, T L Timme, S K Bryan, Robb E Moses | DNA polymerase III of Escherichia col... | |
| 1987 | H Shwartz, Zvi Livneh | Dynamics of termination during in vit... | |
| 1987 | J R Hawker, Charles S McHenry | Monoclonal antibodies specific for th... | |
| 1987 | R Oberfelder, Charles S McHenry | Characterization of 2'(3')-trinitroph... | |
| 1987 | O Kwon-Shin, J B Bodner, Charles S McHenry, Robert A Bambara | Properties of initiation complexes fo... | |
| 1987 | Hisaji Maki, Arthur Kornberg | Proofreading by DNA polymerase III of... | |
| 1987 | Mike E O'Donnell | Accessory proteins bind a primed temp... | |
| 1986 | R J LaDuca, J J Crute, Charles S McHenry, Robert A Bambara | The beta subunit of the Escherichia c... | |
| 1986 | Z Livneh | Replication of UV-irradiated single-s... | |
| 1986 | Zvi Livneh | Mechanism of replication of ultraviol... | |
| 1985 | Charles S McHenry | DNA polymerase III holoenzyme of Esch... | |
| 1985 | Mike E O'Donnell, Arthur Kornberg | Dynamics of DNA polymerase III holoen... | |
| 1985 | Hisaji Maki, Arthur Kornberg | The polymerase subunit of DNA polymer... | |
| 1985 | Mike E O'Donnell, Arthur Kornberg | Complete replication of templates by ... | |
| 1985 | Hisaji Maki, T Horiuchi, Arthur Kornberg | The polymerase subunit of DNA polymer... | |
| 1984 | K O Johanson, Charles S McHenry | Adenosine 5'-O-(3-thiotriphosphate) c... | |
| 1984 | Charles S McHenry, K O Johanson | DNA polymerase III holoenzyme of Esch... | |
| 1984 | Subhasis B Biswas, Arthur Kornberg | Nucleoside triphosphate binding to DN... | |
| 1984 | R H Scheuermann, H Echols | A separate editing exonuclease for DN... | |
| 1984 | Y H Wu, M A Franden, J R Hawker, Charles S McHenry | Monoclonal antibodies specific for th... | |
| 1983 | A R Fersht, J W Knill-Jones | Contribution of 3' leads to 5' exonuc... | |
| 1983 | Peter M J Burgers, Arthur Kornberg | The cycling of Escherichia coli DNA p... | |
| 1983 | R Scheuermann, S Tam, Peter M J Burgers, Chengping Lu, H Echols | Identification of the epsilon-subunit... | |
| 1983 | J J Crute, R J LaDuca, K O Johanson, Charles S McHenry, Robert A Bambara | Excess beta subunit can bypass the AT... | |
| 1983 | R J LaDuca, P J Fay, C Chuang, Charles S McHenry, Robert A Bambara | Site-specific pausing of deoxyribonuc... | |
| 1982 | Peter M J Burgers, Arthur Kornberg | ATP activation of DNA polymerase III ... | |
| 1982 | Charles S McHenry | Purification and characterization of ... | Cloned or native,Tagged,Full length or truncated,Molecular Weight,All properties |
| 1982 | Y Kobayashi, K Kuratomi | Purification involving polymin P frac... | |
| 1982 | P J Fay, K O Johanson, Charles S McHenry, Robert A Bambara | Size classes of products synthesized ... | |
| 1981 | P J Fay, K O Johanson, Charles S McHenry, Robert A Bambara | Size classes of products synthesized ... | |
| 1981 | Ulrich Hübscher, A Spanos, W Albert, F Grummt, G R Banks | Evidence that a high molecular weight... | |
| 1981 | O Niwa, Robb E Moses | Synthesis by DNA polymerase I on bleo... | |
| 1981 | Peter M J Burgers, Arthur Kornberg, Y Sakakibara | The dnaN gene codes for the beta subu... | |
| 1980 | Ulrich Hübscher, Arthur Kornberg | The dnaZ protein, the gamma subunit o... | |
| 1980 | K O Johanson, Charles S McHenry | Purification and characterization of ... | |
| 1979 | Ulrich Hübscher, Arthur Kornberg | The delta subunit of Escherichia coli... | |
| 1979 | Charles S McHenry, W Crow | DNA polymerase III of Escherichia col... | |
| 1978 | M Włodarczyk, M Bednarska | Replication of plasmid R6K in DNA pol... | |
| 1977 | C McHenry, Arthur Kornberg | DNA polymerase III holoenzyme of Esch... | Molecular Weight,All properties |
| 1977 | R Vicuna, Jerard Hurwitz, S Wallace, M Girard | Selective inhibition of in vitro DNA ... | |
| 1976 | S Wickner | Mechanism of DNA elongation catalyzed... | |
| 1975 | D M Livingston, Charles C Richardson | Deoxyribonucleic acid polymerase III ... | |
| 1975 | D M Livingston, David C Hinkle, Charles C Richardson | Deoxyribonucleic acid polymerase III ... | |
| 1974 | Jerard Hurwitz, S Wickner | Involvement of two protein factors an... | |
| 1974 | W Wickner, Arthur Kornberg | A holoenzyme form of deoxyribonucleic... | |
| 1973 | W Wickner, R Schekman, K Geider, Arthur Kornberg | A new form of DNA polymerase 3 and a ... | |
| 1972 | T Kornberg, M L Gefter | Deoxyribonucleic acid synthesis in ce... | |
| 1971 | T Kornberg, M L Gefter | Purification and DNA synthesis in cel... |
Protein sequence:
Predicted Structure Model
Predicted model
AlphaFold DB
Not experimentally determined
This AlphaFold DB model is predicted and not an experimentally determined structure. View AlphaFold DB entry Download predicted model (.pdb)
Confidence legend (pLDDT)
AlphaFold DB colors residues by predicted confidence. Use high-confidence regions for structural context and treat low-confidence regions cautiously.
- Very high (pLDDT > 90) Backbone and side chains are usually reliable.
- Confident (pLDDT 70-90) Overall fold is usually reliable, but some local detail may shift.
- Low (pLDDT 50-70) Use with caution; this region may be flexible or uncertain.
- Very low (pLDDT < 50) Often disordered or not confidently placed.
| Name | 3'-5' exo activity | 5'-3' exo activity | Frameshift Rate | Substitution Rate | General Error Rate |
|---|---|---|---|---|---|
| MutD5 Pol III | No (1) | 5.0e-07-1.0e+02 errors/bp, Mutation frequency (relative to WT) (2) | 3.5e-06-4.4e+01 errors/bp, Mutation frequency (relative to WT) (2) |
Protein information: Uniprot P10443 search for Eco Pol III at UniProt
Sequence information: NCBI nucleotides European nucleotide archive
Predicted structure: AlphaFold DB entry AF-P10443-F1