show help

Results for property: Overall Error Rate

Detailed Results for Property

Use this page to examine all the the polymerases and references referring to the property: Overall Error Rate.

Conflicts: Polbase presents all the values that have been entered, including those that may conflict with each other. Consider the reported context, or refer to the reference for more details.

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

Polymerase Kingdom Family Reference Result Context
T7 Virus/Phage A Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. 2.6E-07 errors/bp
T7 Virus/Phage A Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. 6.7E-06 errors/bp
9egN Archaeon B DNA polymerases from hyperthermophiles. 5.7E-05 errors/bp
Vent Archaeon B PCR fidelity of pfu DNA polymerase and other thermostable DNA polymerases. 2.8E-06 errors/bp
Vent Archaeon B DNA polymerases from hyperthermophiles. 2.8E-06 errors/bp
Vent Archaeon B Optimization of the polymerase chain reaction with regard to fidelity: modified T7, Taq, and vent DNA polymerases. 6.6E-05 errors/bp
T4 D219A Virus/Phage B Effect of accessory proteins on T4 DNA polymerase replication fidelity. 1.2E-05 errors/bp
T4 Virus/Phage B A constant rate of spontaneous mutation in DNA-based microbes. 2E-08 errors/bp Technique: rII+ reversion
T4 A737V Virus/Phage B The spectrum of acridine resistant mutants of bacteriophage T4 reveals cryptic effects of the tsL141 DNA polymerase allele on spontaneous mutagenesis. 1 Mutation frequency (relative to WT) Technique: Sequencing
Eco Pol I Eubacterium A Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis. 0.00138 errors/bp
Eco Pol I Eubacterium A Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. 0.00053 errors/bp
Eco Pol I Eubacterium A Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis. 0.00078 errors/bp
Eco Pol I Eubacterium A Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. 0.00017 errors/bp
Eco Pol I Eubacterium A Polymerase-specific differences in the DNA intermediates of frameshift mutagenesis. In vitro synthesis errors of Escherichia coli DNA polymerase I and its large fragment derivative. 7.1E-05 errors/bp Technique: Blue/white screening
Klenow fragment Eubacterium A The mutational specificity of the Dbh lesion bypass polymerase and its implications. 0.00038 errors/bp
Klenow fragment Eubacterium A Analyzing fidelity of DNA polymerases. 0.0052 errors/bp Technique: M13mp2 forward mutation assay
Klenow fragment Eubacterium A Analyzing fidelity of DNA polymerases. 7.7E-05 errors/bp Technique: M13mp2 opal codon reversion assay
Klenow fragment Eubacterium A A thumb subdomain mutant of the large fragment of Escherichia coli DNA polymerase I with reduced DNA binding affinity, processivity, and frameshift fidelity. 4E-05 errors/bp
Klenow fragment Eubacterium A Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase. 0.0044 errors/bp
Klenow fragment Eubacterium A Polymerase-specific differences in the DNA intermediates of frameshift mutagenesis. In vitro synthesis errors of Escherichia coli DNA polymerase I and its large fragment derivative. 5.8E-05 errors/bp
Dpo4 Archaeon Y Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. 0.0032 errors/bp
Dpo4 Archaeon Y Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. 0.00015 errors/bp
Human Pol eta Eukaryote Y Emerging links between hypermutation of antibody genes and DNA polymerases. 0.03 errors/bp Technique: Sequencing
Human Pol gamma Eukaryote A Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. 0.00029 errors/bp
Human Pol gamma Eukaryote A Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. 1.8E-06 errors/bp
Eco Pol IV Eubacterium Y Fidelity of Escherichia coli DNA polymerase IV. Preferential generation of small deletion mutations by dNTP-stabilized misalignment. 0.03 errors/bp
Eco Pol IV Eubacterium Y Fidelity of Escherichia coli DNA polymerase IV. Preferential generation of small deletion mutations by dNTP-stabilized misalignment. 0.036 errors/bp
Eco Pol V Eubacterium Y Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis. 0.02325 errors/bp
Human Pol beta Eukaryote X The mutational specificity of DNA polymerase-beta during in vitro DNA synthesis. Production of frameshift, base substitution, and deletion mutations. 0.076 errors/bp Technique: M13mp2 forward mutation assay
Human Pol beta Eukaryote X DNA polymerase family X: function, structure, and cellular roles. 0.0005 errors/bp
Human Pol beta Eukaryote X DNA polymerase family X: function, structure, and cellular roles. 0.0024 errors/bp
Rat Pol beta Eukaryote X The mutational specificity of DNA polymerase-beta during in vitro DNA synthesis. Production of frameshift, base substitution, and deletion mutations. 0.064 errors/bp Technique: M13mp2 forward mutation assay
Taq pol I Eubacterium A A plasmid-based lacZα gene assay for DNA polymerase fidelity measurement. 1.1E-05 errors/bp
Taq pol I Eubacterium A Characterization and PCR optimization of the thermostable family B DNA polymerase from Thermococcus guaymasensis 1.213E-05 errors/bp
Taq pol I Eubacterium A DNA polymerases from hyperthermophiles. 8E-06 errors/bp
Taq pol I Eubacterium A Optimization of the polymerase chain reaction with regard to fidelity: modified T7, Taq, and vent DNA polymerases. 0.0002 errors/bp
Taq pol I Eubacterium A Optimization of the polymerase chain reaction with regard to fidelity: modified T7, Taq, and vent DNA polymerases. 7.2E-05 errors/bp
Taq pol I Eubacterium A A plasmid-based lacZα gene assay for DNA polymerase fidelity measurement. 1E-05 errors/bp Technique: Blue/white screening (pSJ2)
Taq pol I Eubacterium A PCR fidelity of pfu DNA polymerase and other thermostable DNA polymerases. 8E-06 errors/bp
HIV RT Virus/Phage RT In vitro fidelity of the prototype primate foamy virus (PFV) RT compared to HIV-1 RT. 7.5E-05 errors/bp
HIV RT Virus/Phage RT Analyzing fidelity of DNA polymerases. 0.08 errors/bp Technique: M13mp2 forward mutation assay
HIV RT Virus/Phage RT Analyzing fidelity of DNA polymerases. 0.0001 errors/bp Technique: M13mp2 opal codon reversion assay
HIV RT Virus/Phage RT Comparison of DNA polymerase activities between recombinant feline immunodeficiency and leukemia virus reverse transcriptases. 0.0005 errors/bp
Pfu Archaeon B PCR fidelity of pfu DNA polymerase and other thermostable DNA polymerases. 1.3E-06 errors/bp
Pfu Archaeon B In vitro replication slippage by DNA polymerases from thermophilic organisms. 1.3E-06 errors/bp
Pfu Archaeon B A plasmid-based lacZα gene assay for DNA polymerase fidelity measurement. 1.6E-06 errors/bp Technique: Blue/white screening (pSJ2)
Pfu Archaeon B A plasmid-based lacZα gene assay for DNA polymerase fidelity measurement. 3.5E-06 errors/bp Technique: Blue/white screening (pSJ3)
Pfu Archaeon B Characterization and PCR optimization of the thermostable family B DNA polymerase from Thermococcus guaymasensis 2.18E-06 errors/bp
Pfu Archaeon B DNA polymerases from hyperthermophiles. 1.3E-06 errors/bp
Eco Pol III Eubacterium C Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis. 0.00098 errors/bp
Eco Pol III Eubacterium C Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis. 0.00081 errors/bp
Human Pol iota Eukaryote Y Emerging links between hypermutation of antibody genes and DNA polymerases. 0.3 errors/bp Technique: Sequencing
Human Pol iota Eukaryote Y Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates. 0.0002 errors/bp
Phi29 Virus/Phage B TempliPhi, phi29 DNA polymerase based rolling circle amplification of templates for DNA sequencing. 3E-06 errors/bp
PGBD Pol I Archaeon B DNA polymerases from hyperthermophiles. 2.7E-06 errors/bp
Sequenase Virus/Phage A Optimization of the polymerase chain reaction with regard to fidelity: modified T7, Taq, and vent DNA polymerases. 5.4E-05 errors/bp
Sequenase Virus/Phage A Optimization of the polymerase chain reaction with regard to fidelity: modified T7, Taq, and vent DNA polymerases. 4.4E-05 errors/bp
AMV Virus/Phage RT Mutation Rates and Intrinsic Fidelity of Retroviral Reverse Transcriptases 5.9E-05 errors/bp Technique: M13mp2 forward mutation assay
Human Pol alpha Eukaryote B Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III. 0.003 errors/bp Technique: M13mp2 forward mutation assay
Human Pol alpha Eukaryote B Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III. 5E-05 errors/bp Technique: Forward mutational
Eco Pol II Eubacterium B Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis. 0.00065 errors/bp
Eco Pol II Eubacterium B Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis. 0.00148 errors/bp
Human Pol theta Eukaryote A Low-fidelity DNA synthesis by human DNA polymerase theta. 0.0014 errors/bp Technique: M13mp2 forward mutation assay (Single base deletions)
Human Pol theta Eukaryote A The human DINB1 gene encodes the DNA polymerase Poltheta. 0.001 errors/bp
Human Pol theta Eukaryote A The human DINB1 gene encodes the DNA polymerase Poltheta. 0.01 errors/bp
Human Pol theta Eukaryote A Low-fidelity DNA synthesis by human DNA polymerase theta. 0.0033 errors/bp Technique: M13mp2 forward mutation assay (Single base additions)
Tgu Archaeon B Characterization and PCR optimization of the thermostable family B DNA polymerase from Thermococcus guaymasensis 3.17E-06 errors/bp Technique: Blue/white screening
ASFV pol X Virus/Phage X DNA polymerase X of African swine fever virus: insertion fidelity on gapped DNA substrates and AP lyase activity support a role in base excision repair of viral DNA. 0.00024 errors/bp
1175P ? Vent lysate Archaeon B PCR fidelity of pfu DNA polymerase and other thermostable DNA polymerases. 2.7E-06 errors/bp
Pab Pol I Archaeon B PCR performance of the highly thermostable proof-reading B-type DNA polymerase from Pyrococcus abyssi. 4.7E-06 errors/bp
Pab Pol I Archaeon B PCR performance of the highly thermostable proof-reading B-type DNA polymerase from Pyrococcus abyssi. 6.6E-07 errors/bp
FeLV RT Virus/Phage RT Mutation Rates and Intrinsic Fidelity of Retroviral Reverse Transcriptases 5.8E-06 errors/bp Technique: M13mp2 forward mutation assay
FeLV RT Virus/Phage RT Comparison of DNA polymerase activities between recombinant feline immunodeficiency and leukemia virus reverse transcriptases. 0.00088 errors/bp Technique: M13mp2 forward mutation assay
FIV RT Virus/Phage RT Comparison of DNA polymerase activities between recombinant feline immunodeficiency and leukemia virus reverse transcriptases. 0.00942 errors/bp Technique: M13mp2 forward mutation assay
FIV RT Virus/Phage RT Mutation Rates and Intrinsic Fidelity of Retroviral Reverse Transcriptases 6.2E-05 errors/bp Technique: M13mp2 forward mutation assay
PFV RT Virus/Phage RT Mutation Rates and Intrinsic Fidelity of Retroviral Reverse Transcriptases 0.00017 errors/bp Technique: M13mp2 forward mutation assay
PFV RT Virus/Phage RT In vitro fidelity of the prototype primate foamy virus (PFV) RT compared to HIV-1 RT. 0.00017 errors/bp
Human pol gamma (exo-) Eukaryote A The fidelity of human DNA polymerase gamma with and without exonucleolytic proofreading and the p55 accessory subunit. 0.0062 errors/bp
Chicken Pol beta Eukaryote X The mutational specificity of DNA polymerase-beta during in vitro DNA synthesis. Production of frameshift, base substitution, and deletion mutations. 0.035 errors/bp Technique: M13mp2 forward mutation assay
Pfu (exo-) Archaeon D PCR fidelity of pfu DNA polymerase and other thermostable DNA polymerases. 5E-05 errors/bp
UlTma ? ? PCR fidelity of pfu DNA polymerase and other thermostable DNA polymerases. 5E-05 errors/bp
Sce Pol I Eukaryote B Fidelity of DNA polymerase I and the DNA polymerase I-DNA primase complex from Saccharomyces cerevisiae. 0.000111 errors/bp Technique: M13mp2 opal codon reversion assay
Bovine pol epsilon Eukaryote B Analyzing fidelity of DNA polymerases. 0.0007 errors/bp Technique: M13mp2 forward mutation assay
Bovine pol epsilon Eukaryote B Analyzing fidelity of DNA polymerases. 5E-06 errors/bp Technique: M13mp2 opal codon reversion assay
Mouse pol elta Eukaryote ? Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesis. 1E-05 errors/bp
Pfu (exo-) ? ? DNA polymerases from hyperthermophiles. 4.7E-05 errors/bp
Human Pol zeta Eukaryote B Emerging links between hypermutation of antibody genes and DNA polymerases. 0.0005 errors/bp Technique: Sequencing
Pfu D215AE143A Archaeon B A plasmid-based lacZα gene assay for DNA polymerase fidelity measurement. 6.7E-06 errors/bp
Pfu D215AE143A Archaeon B A plasmid-based lacZα gene assay for DNA polymerase fidelity measurement. 6.3E-06 errors/bp Technique: Blue/white screening (pSJ2)
Pfu D215AE143A/D473G Archaeon B A plasmid-based lacZα gene assay for DNA polymerase fidelity measurement. 1.8E-05 errors/bp Technique: Blue/white screening (pSJ2)
Pfu D215AE143A/D473G Archaeon B A plasmid-based lacZα gene assay for DNA polymerase fidelity measurement. 2.4E-05 errors/bp

Version:20241218

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.