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Results for property: Overall Error Rate

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Use this page to examine all the the polymerases and references referring to the property: Overall Error Rate.

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Polymerase Kingdom Family Reference Result Context
T7 Virus/Phage A Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. 2.6E-07 errors/bp
T7 Virus/Phage A Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. 6.7E-06 errors/bp
9egN Archaeon B DNA polymerases from hyperthermophiles. 5.7E-05 errors/bp
Vent Archaeon B PCR fidelity of pfu DNA polymerase and other thermostable DNA polymerases. 2.8E-06 errors/bp
Vent Archaeon B DNA polymerases from hyperthermophiles. 2.8E-06 errors/bp
Vent Archaeon B Optimization of the polymerase chain reaction with regard to fidelity: modified T7, Taq, and vent DNA polymerases. 6.6E-05 errors/bp
T4 D219A Virus/Phage B Effect of accessory proteins on T4 DNA polymerase replication fidelity. 1.2E-05 errors/bp
T4 Virus/Phage B A constant rate of spontaneous mutation in DNA-based microbes. 2E-08 errors/bp Technique: rII+ reversion
T4 A737V Virus/Phage B The spectrum of acridine resistant mutants of bacteriophage T4 reveals cryptic effects of the tsL141 DNA polymerase allele on spontaneous mutagenesis. 1 Mutation frequency (relative to WT) Technique: Sequencing
Eco Pol I Eubacterium A Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis. 0.00138 errors/bp
Eco Pol I Eubacterium A Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. 0.00053 errors/bp
Eco Pol I Eubacterium A Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis. 0.00078 errors/bp
Eco Pol I Eubacterium A Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. 0.00017 errors/bp
Eco Pol I Eubacterium A Polymerase-specific differences in the DNA intermediates of frameshift mutagenesis. In vitro synthesis errors of Escherichia coli DNA polymerase I and its large fragment derivative. 7.1E-05 errors/bp Technique: Blue/white screening
Klenow fragment Eubacterium A The mutational specificity of the Dbh lesion bypass polymerase and its implications. 0.00038 errors/bp
Klenow fragment Eubacterium A Analyzing fidelity of DNA polymerases. 0.0052 errors/bp Technique: M13mp2 forward mutation assay
Klenow fragment Eubacterium A Analyzing fidelity of DNA polymerases. 7.7E-05 errors/bp Technique: M13mp2 opal codon reversion assay
Klenow fragment Eubacterium A A thumb subdomain mutant of the large fragment of Escherichia coli DNA polymerase I with reduced DNA binding affinity, processivity, and frameshift fidelity. 4E-05 errors/bp
Klenow fragment Eubacterium A Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase. 0.0044 errors/bp
Klenow fragment Eubacterium A Polymerase-specific differences in the DNA intermediates of frameshift mutagenesis. In vitro synthesis errors of Escherichia coli DNA polymerase I and its large fragment derivative. 5.8E-05 errors/bp
Dpo4 Archaeon Y Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. 0.0032 errors/bp
Dpo4 Archaeon Y Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. 0.00015 errors/bp
Human Pol eta Eukaryote Y Emerging links between hypermutation of antibody genes and DNA polymerases. 0.03 errors/bp Technique: Sequencing
Human Pol gamma Eukaryote A Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. 0.00029 errors/bp
Human Pol gamma Eukaryote A Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. 1.8E-06 errors/bp
Eco Pol IV Eubacterium Y Fidelity of Escherichia coli DNA polymerase IV. Preferential generation of small deletion mutations by dNTP-stabilized misalignment. 0.03 errors/bp
Eco Pol IV Eubacterium Y Fidelity of Escherichia coli DNA polymerase IV. Preferential generation of small deletion mutations by dNTP-stabilized misalignment. 0.036 errors/bp
Eco Pol V Eubacterium Y Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis. 0.02325 errors/bp
Human Pol beta Eukaryote X The mutational specificity of DNA polymerase-beta during in vitro DNA synthesis. Production of frameshift, base substitution, and deletion mutations. 0.076 errors/bp Technique: M13mp2 forward mutation assay
Human Pol beta Eukaryote X DNA polymerase family X: function, structure, and cellular roles. 0.0005 errors/bp
Human Pol beta Eukaryote X DNA polymerase family X: function, structure, and cellular roles. 0.0024 errors/bp
Rat Pol beta Eukaryote X The mutational specificity of DNA polymerase-beta during in vitro DNA synthesis. Production of frameshift, base substitution, and deletion mutations. 0.064 errors/bp Technique: M13mp2 forward mutation assay
Taq pol I Eubacterium A A plasmid-based lacZα gene assay for DNA polymerase fidelity measurement. 1.1E-05 errors/bp
Taq pol I Eubacterium A Characterization and PCR optimization of the thermostable family B DNA polymerase from Thermococcus guaymasensis 1.213E-05 errors/bp
Taq pol I Eubacterium A DNA polymerases from hyperthermophiles. 8E-06 errors/bp
Taq pol I Eubacterium A Optimization of the polymerase chain reaction with regard to fidelity: modified T7, Taq, and vent DNA polymerases. 0.0002 errors/bp
Taq pol I Eubacterium A Optimization of the polymerase chain reaction with regard to fidelity: modified T7, Taq, and vent DNA polymerases. 7.2E-05 errors/bp
Taq pol I Eubacterium A A plasmid-based lacZα gene assay for DNA polymerase fidelity measurement. 1E-05 errors/bp Technique: Blue/white screening (pSJ2)
Taq pol I Eubacterium A PCR fidelity of pfu DNA polymerase and other thermostable DNA polymerases. 8E-06 errors/bp
HIV RT Virus/Phage RT In vitro fidelity of the prototype primate foamy virus (PFV) RT compared to HIV-1 RT. 7.5E-05 errors/bp
HIV RT Virus/Phage RT Analyzing fidelity of DNA polymerases. 0.08 errors/bp Technique: M13mp2 forward mutation assay
HIV RT Virus/Phage RT Analyzing fidelity of DNA polymerases. 0.0001 errors/bp Technique: M13mp2 opal codon reversion assay
HIV RT Virus/Phage RT Comparison of DNA polymerase activities between recombinant feline immunodeficiency and leukemia virus reverse transcriptases. 0.0005 errors/bp
Pfu Archaeon B PCR fidelity of pfu DNA polymerase and other thermostable DNA polymerases. 1.3E-06 errors/bp
Pfu Archaeon B In vitro replication slippage by DNA polymerases from thermophilic organisms. 1.3E-06 errors/bp
Pfu Archaeon B A plasmid-based lacZα gene assay for DNA polymerase fidelity measurement. 1.6E-06 errors/bp Technique: Blue/white screening (pSJ2)
Pfu Archaeon B A plasmid-based lacZα gene assay for DNA polymerase fidelity measurement. 3.5E-06 errors/bp Technique: Blue/white screening (pSJ3)
Pfu Archaeon B Characterization and PCR optimization of the thermostable family B DNA polymerase from Thermococcus guaymasensis 2.18E-06 errors/bp
Pfu Archaeon B DNA polymerases from hyperthermophiles. 1.3E-06 errors/bp
Eco Pol III Eubacterium C Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis. 0.00098 errors/bp
Eco Pol III Eubacterium C Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis. 0.00081 errors/bp
Human Pol iota Eukaryote Y Emerging links between hypermutation of antibody genes and DNA polymerases. 0.3 errors/bp Technique: Sequencing
Human Pol iota Eukaryote Y Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates. 0.0002 errors/bp
Phi29 Virus/Phage B TempliPhi, phi29 DNA polymerase based rolling circle amplification of templates for DNA sequencing. 3E-06 errors/bp
PGBD Pol I Archaeon B DNA polymerases from hyperthermophiles. 2.7E-06 errors/bp
Sequenase Virus/Phage A Optimization of the polymerase chain reaction with regard to fidelity: modified T7, Taq, and vent DNA polymerases. 5.4E-05 errors/bp
Sequenase Virus/Phage A Optimization of the polymerase chain reaction with regard to fidelity: modified T7, Taq, and vent DNA polymerases. 4.4E-05 errors/bp
AMV Virus/Phage RT Mutation Rates and Intrinsic Fidelity of Retroviral Reverse Transcriptases 5.9E-05 errors/bp Technique: M13mp2 forward mutation assay
Human Pol alpha Eukaryote B Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III. 0.003 errors/bp Technique: M13mp2 forward mutation assay
Human Pol alpha Eukaryote B Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III. 5E-05 errors/bp Technique: Forward mutational
Eco Pol II Eubacterium B Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis. 0.00065 errors/bp
Eco Pol II Eubacterium B Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis. 0.00148 errors/bp
Human Pol theta Eukaryote A Low-fidelity DNA synthesis by human DNA polymerase theta. 0.0014 errors/bp Technique: M13mp2 forward mutation assay (Single base deletions)
Human Pol theta Eukaryote A The human DINB1 gene encodes the DNA polymerase Poltheta. 0.001 errors/bp
Human Pol theta Eukaryote A The human DINB1 gene encodes the DNA polymerase Poltheta. 0.01 errors/bp
Human Pol theta Eukaryote A Low-fidelity DNA synthesis by human DNA polymerase theta. 0.0033 errors/bp Technique: M13mp2 forward mutation assay (Single base additions)
Tgu Archaeon B Characterization and PCR optimization of the thermostable family B DNA polymerase from Thermococcus guaymasensis 3.17E-06 errors/bp Technique: Blue/white screening
ASFV pol X Virus/Phage X DNA polymerase X of African swine fever virus: insertion fidelity on gapped DNA substrates and AP lyase activity support a role in base excision repair of viral DNA. 0.00024 errors/bp
1175P ? Vent lysate Archaeon B PCR fidelity of pfu DNA polymerase and other thermostable DNA polymerases. 2.7E-06 errors/bp
Pab Pol I Archaeon B PCR performance of the highly thermostable proof-reading B-type DNA polymerase from Pyrococcus abyssi. 4.7E-06 errors/bp
Pab Pol I Archaeon B PCR performance of the highly thermostable proof-reading B-type DNA polymerase from Pyrococcus abyssi. 6.6E-07 errors/bp
FeLV RT Virus/Phage RT Mutation Rates and Intrinsic Fidelity of Retroviral Reverse Transcriptases 5.8E-06 errors/bp Technique: M13mp2 forward mutation assay
FeLV RT Virus/Phage RT Comparison of DNA polymerase activities between recombinant feline immunodeficiency and leukemia virus reverse transcriptases. 0.00088 errors/bp Technique: M13mp2 forward mutation assay
FIV RT Virus/Phage RT Comparison of DNA polymerase activities between recombinant feline immunodeficiency and leukemia virus reverse transcriptases. 0.00942 errors/bp Technique: M13mp2 forward mutation assay
FIV RT Virus/Phage RT Mutation Rates and Intrinsic Fidelity of Retroviral Reverse Transcriptases 6.2E-05 errors/bp Technique: M13mp2 forward mutation assay
PFV RT Virus/Phage RT Mutation Rates and Intrinsic Fidelity of Retroviral Reverse Transcriptases 0.00017 errors/bp Technique: M13mp2 forward mutation assay
PFV RT Virus/Phage RT In vitro fidelity of the prototype primate foamy virus (PFV) RT compared to HIV-1 RT. 0.00017 errors/bp
Human pol gamma (exo-) Eukaryote A The fidelity of human DNA polymerase gamma with and without exonucleolytic proofreading and the p55 accessory subunit. 0.0062 errors/bp
Chicken Pol beta Eukaryote X The mutational specificity of DNA polymerase-beta during in vitro DNA synthesis. Production of frameshift, base substitution, and deletion mutations. 0.035 errors/bp Technique: M13mp2 forward mutation assay
Pfu (exo-) Archaeon D PCR fidelity of pfu DNA polymerase and other thermostable DNA polymerases. 5E-05 errors/bp
UlTma ? ? PCR fidelity of pfu DNA polymerase and other thermostable DNA polymerases. 5E-05 errors/bp
Sce Pol I Eukaryote B Fidelity of DNA polymerase I and the DNA polymerase I-DNA primase complex from Saccharomyces cerevisiae. 0.000111 errors/bp Technique: M13mp2 opal codon reversion assay
Bovine pol epsilon Eukaryote B Analyzing fidelity of DNA polymerases. 0.0007 errors/bp Technique: M13mp2 forward mutation assay
Bovine pol epsilon Eukaryote B Analyzing fidelity of DNA polymerases. 5E-06 errors/bp Technique: M13mp2 opal codon reversion assay
Mouse pol elta Eukaryote ? Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesis. 1E-05 errors/bp
Pfu (exo-) ? ? DNA polymerases from hyperthermophiles. 4.7E-05 errors/bp
Human Pol zeta Eukaryote B Emerging links between hypermutation of antibody genes and DNA polymerases. 0.0005 errors/bp Technique: Sequencing
Pfu D215AE143A Archaeon B A plasmid-based lacZα gene assay for DNA polymerase fidelity measurement. 6.7E-06 errors/bp
Pfu D215AE143A Archaeon B A plasmid-based lacZα gene assay for DNA polymerase fidelity measurement. 6.3E-06 errors/bp Technique: Blue/white screening (pSJ2)
Pfu D215AE143A/D473G Archaeon B A plasmid-based lacZα gene assay for DNA polymerase fidelity measurement. 1.8E-05 errors/bp Technique: Blue/white screening (pSJ2)
Pfu D215AE143A/D473G Archaeon B A plasmid-based lacZα gene assay for DNA polymerase fidelity measurement. 2.4E-05 errors/bp

Version:20241007

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.