T7 |
Virus/Phage |
A
|
Characterization of bacteriophage T7 DNA polymerase purified to homogeneity by antithioredoxin immunoadsorbent chromatography. |
Cloned in E. coli |
|
T7 |
Virus/Phage |
A
|
T7-induced DNA polymerase. Requirement for thioredoxin sulfhydryl groups. |
Native organism |
|
T7 |
Virus/Phage |
A
|
Deoxyribonucleic acid polymerase of bacteriophage T7. |
Native organism |
|
T7 |
Virus/Phage |
A
|
Error-prone replication of repeated DNA sequences by T7 DNA polymerase in the absence of its processivity subunit. |
Native organism |
|
T7 |
Virus/Phage |
A
|
Bacteriophage T7 Deoxyribonucleic acid replication in vitro. A protein of Escherichia coli required for bacteriophage T7 DNA polymerase activity. |
Native organism |
|
T7 |
Virus/Phage |
A
|
Deoxyribonucleic acid polymerase of bacteriophage T7. Purification and properties of the phage-encoded subunit, the gene 5 protein. |
Native organism |
|
T7 |
Virus/Phage |
A
|
Characterization of strand displacement synthesis catalyzed by bacteriophage T7 DNA polymerase. |
Native organism |
|
T7 |
Virus/Phage |
A
|
T7-induced DNA polymerase. Characterization of associated exonuclease activities and resolution into biologically active subunits. |
Native organism |
|
T7 |
Virus/Phage |
A
|
Two forms of the DNA polymerase of bacteriophage T7. |
Cloned in E. coli |
|
T7 |
Virus/Phage |
A
|
Escherichia coli thioredoxin confers processivity on the DNA polymerase activity of the gene 5 protein of bacteriophage T7. |
Cloned in E. coli |
|
T7 |
Virus/Phage |
A
|
Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant. |
Cloned in E. coli |
|
T7 |
Virus/Phage |
A
|
Bacteriophage T7 deoxyribonucleic acid replication invitro. Bacteriophage T7 DNA polymerase: an an emzyme composed of phage- and host-specific subunits. |
Native organism |
|
9egN |
Archaeon |
B
|
Cloning of thermostable DNA polymerases from hyperthermophilic marine Archaea with emphasis on Thermococcus sp. 9 degrees N-7 and mutations affecting 3'-5' exonuclease activity. |
Cloned in E. coli |
|
TGO |
Archaeon |
B
|
Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius. |
Cloned in yeast |
|
RB69 |
Virus/Phage |
B
|
Structure and enzymatic properties of a chimeric bacteriophage RB69 DNA polymerase and single-stranded DNA binding protein with increased processivity. |
Cloned in E. coli |
|
Vent |
Archaeon |
B
|
Incorporation of reporter-labeled nucleotides by DNA polymerases. |
Unspecified |
|
Vent |
Archaeon |
B
|
Characterization of a DNA polymerase from the hyperthermophile archaea Thermococcus litoralis. Vent DNA polymerase, steady state kinetics, thermal stability, processivity, strand displacement, and exonuclease activities. |
Native organism |
|
Vent |
Archaeon |
B
|
Fidelity of DNA synthesis by the Thermococcus litoralis DNA polymerase--an extremely heat stable enzyme with proofreading activity. |
Native organism |
|
Vent A488L |
Archaeon |
B
|
Comparative kinetics of nucleotide analog incorporation by vent DNA polymerase. |
Cloned in E. coli |
|
T4 |
Virus/Phage |
B
|
Dissociation of bacteriophage T4 DNA polymerase and its processivity clamp after completion of Okazaki fragment synthesis. |
Cloned in E. coli |
|
T4 |
Virus/Phage |
B
|
Incorporation of reporter-labeled nucleotides by DNA polymerases. |
Unspecified |
|
T4 |
Virus/Phage |
B
|
A single mutation in bacteriophage T4 DNA polymerase (A737V, tsL141) decreases its processivity as a polymerase and increases its processivity as a 3'-->5' exonuclease. |
Cloned in E. coli |
|
T4 |
Virus/Phage |
B
|
The slow dissociation of the T4 DNA polymerase holoenzyme when stalled by nucleotide omission. An indication of a highly processive enzyme. |
Cloned in E. coli |
|
T4 |
Virus/Phage |
B
|
On the exonuclease activity of phage T4 deoxyribonucleic acid polymerase. |
Native organism |
|
T4 |
Virus/Phage |
B
|
On the role of deoxyribonucleic acid polymerase in determining mutation rates. Characterization of the defect in the T4 deoxyribonucleic acid polymerase caused by the ts L88 mutation. |
Native organism |
|
T4 A737V |
Virus/Phage |
B
|
A single mutation in bacteriophage T4 DNA polymerase (A737V, tsL141) decreases its processivity as a polymerase and increases its processivity as a 3'-->5' exonuclease. |
Cloned in E. coli |
|
T4 L771F |
Virus/Phage |
B
|
A single mutation in bacteriophage T4 DNA polymerase (A737V, tsL141) decreases its processivity as a polymerase and increases its processivity as a 3'-->5' exonuclease. |
Cloned in E. coli |
|
Eco Pol I |
Eubacterium |
A
|
Processive DNA synthesis by DNA polymerase II mediated by DNA polymerase III accessory proteins. |
Native organism |
|
Eco Pol I |
Eubacterium |
A
|
On the processive mechanism of Escherichia coli DNA polymerase I. Quantitative assessment of processivity. |
Cloned in E. coli |
|
Eco Pol I |
Eubacterium |
A
|
Enzymatic synthesis of deoxyribonucleic acid. XXVII. Chemical modifications of deoxyribonucleic acid polymerase. |
Cloned in E. coli |
|
Eco Pol I |
Eubacterium |
A
|
Characterization of DNA polymerase I*, a form of DNA polymerase I found in Escherichia coli expressing SOS functions. |
Native organism |
|
Eco Pol I |
Eubacterium |
A
|
Incorporation of reporter-labeled nucleotides by DNA polymerases. |
Unspecified |
|
Eco Pol I |
Eubacterium |
A
|
Short deoxyribonucleic acid repair patch length in Escherichia coli is determined by the processive mechanism of deoxyribonucleic acid polymerase I. |
Native organism |
|
Klenow fragment |
Eubacterium |
A
|
Construction of a plasmid that overproduces the large proteolytic fragment (Klenow fragment) of DNA polymerase I of Escherichia coli. |
Cloned in E. coli |
|
Klenow fragment |
Eubacterium |
A
|
Fingers-closing and other rapid conformational changes in DNA polymerase I (Klenow fragment) and their role in nucleotide selectivity. |
Cloned in E. coli |
|
Klenow fragment |
Eubacterium |
A
|
Genetic and crystallographic studies of the 3',5'-exonucleolytic site of DNA polymerase I. |
Cloned in E. coli |
|
Klenow fragment |
Eubacterium |
A
|
Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP. |
Cloned in E. coli |
|
Klenow fragment |
Eubacterium |
A
|
Selective elimination of the exonuclease activity of the deoxyribonucleic acid polymerase from Escherichia coli B by limited proteolysis. |
Native organism |
|
Klenow fragment |
Eubacterium |
A
|
The 3'-5' exonuclease of DNA polymerase I of Escherichia coli: contribution of each amino acid at the active site to the reaction. |
Cloned in E. coli |
|
Klenow fragment |
Eubacterium |
A
|
A thumb subdomain mutant of the large fragment of Escherichia coli DNA polymerase I with reduced DNA binding affinity, processivity, and frameshift fidelity. |
Native organism |
|
Dpo4 |
Archaeon |
Y
|
Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. |
Cloned in E. coli |
|
Dpo4 |
Archaeon |
Y
|
Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): an archaeal DinB-like DNA polymerase with lesion-bypass properties akin to eukaryotic poleta. |
Cloned in E. coli |
|
Dpo4 |
Archaeon |
Y
|
Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication. |
Cloned in E. coli |
|
Human Pol eta |
Eukaryote |
Y
|
Error rate and specificity of human and murine DNA polymerase eta. |
Insect cells |
|
Human Pol gamma |
Eukaryote |
A
|
The mitochondrial p55 accessory subunit of human DNA polymerase gamma enhances DNA binding, promotes processive DNA synthesis, and confers N-ethylmaleimide resistance. |
Native organism |
|
Human Pol gamma |
Eukaryote |
A
|
Characterization of the native and recombinant catalytic subunit of human DNA polymerase gamma: identification of residues critical for exonuclease activity and dideoxynucleotide sensitivity. |
Native organism |
|
Human Pol gamma |
Eukaryote |
A
|
Structural insight into processive human mitochondrial DNA synthesis and disease-related polymerase mutations. |
Cloned in E. coli |
|
Human Pol gamma |
Eukaryote |
A
|
Characterization of the native and recombinant catalytic subunit of human DNA polymerase gamma: identification of residues critical for exonuclease activity and dideoxynucleotide sensitivity. |
Cloned in E. coli |
|
Human Pol gamma |
Eukaryote |
A
|
Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers. |
Insect cells |
|
Eco Pol IV |
Eubacterium |
Y
|
The dinB gene encodes a novel E. coli DNA polymerase, DNA pol IV, involved in mutagenesis. |
Cloned in E. coli |
|
Eco Pol IV |
Eubacterium |
Y
|
The beta clamp targets DNA polymerase IV to DNA and strongly increases its processivity. |
Native organism |
|
Eco Pol IV |
Eubacterium |
Y
|
Fidelity of Escherichia coli DNA polymerase IV. Preferential generation of small deletion mutations by dNTP-stabilized misalignment. |
Native organism |
|
Eco Pol V |
Eubacterium |
Y
|
Purification and characterization of an inducible Escherichia coli DNA polymerase capable of insertion and bypass at abasic lesions in DNA. |
Native organism |
|
Human Pol kappa |
Eukaryote |
Y
|
Purification and characterization of pol kappa, a DNA polymerase encoded by the human DINB1 gene. |
Insect cells |
|
Human Pol kappa |
Eukaryote |
Y
|
Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene. |
Native organism |
|
Human Pol beta |
Eukaryote |
X
|
Expression of human DNA polymerase beta in Escherichia coli and characterization of the recombinant enzyme. |
Cloned in E. coli |
|
Human Pol beta |
Eukaryote |
X
|
Human DNA polymerases alpha and beta are able to incorporate anti-HIV deoxynucleotides into DNA. |
Native organism |
|
Rat Pol beta |
Eukaryote |
X
|
The mutational specificity of DNA polymerase-beta during in vitro DNA synthesis. Production of frameshift, base substitution, and deletion mutations. |
Native organism |
|
T5 |
Virus/Phage |
A
|
Exonuclease associated with bacteriophage T5-Induced DNA polymerase. |
Cloned in E. coli |
|
Taq pol I |
Eubacterium |
A
|
Nucleotide sequence of the Escherichia coli polA gene and primary structure of DNA polymerase I. |
Cloned in yeast |
|
Taq pol I |
Eubacterium |
A
|
High fidelity DNA synthesis by the Thermus aquaticus DNA polymerase. |
Cloned in E. coli |
|
Taq pol I |
Eubacterium |
A
|
Incorporation of reporter-labeled nucleotides by DNA polymerases. |
Unspecified |
|
Taq pol I |
Eubacterium |
A
|
High-level expression, purification, and enzymatic characterization of full-length Thermus aquaticus DNA polymerase and a truncated form deficient in 5' to 3' exonuclease activity. |
Cloned in E. coli |
|
HIV RT |
Virus/Phage |
RT
|
Fidelity of DNA synthesis catalyzed by human DNA polymerase alpha and HIV-1 reverse transcriptase: effect of reaction pH. |
Cloned in E. coli |
|
HIV RT |
Virus/Phage |
RT
|
The K65R mutation confers increased DNA polymerase processivity to HIV-1 reverse transcriptase. |
Cloned in E. coli |
|
HIV RT |
Virus/Phage |
RT
|
N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance. |
Cloned in E. coli |
|
HIV RT |
Virus/Phage |
RT
|
Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex. |
Cloned in E. coli |
|
Pfu |
Archaeon |
B
|
High-fidelity amplification using a thermostable DNA polymerase isolated from Pyrococcus furiosus. |
Native organism |
|
Pfu |
Archaeon |
B
|
Incorporation of reporter-labeled nucleotides by DNA polymerases. |
Unspecified |
|
Eco Pol III |
Eubacterium |
C
|
The base substitution and frameshift fidelity of Escherichia coli DNA polymerase III holoenzyme in vitro. |
Native organism |
|
Eco Pol III |
Eubacterium |
C
|
Purification and characterization of DNA polymerase III'. Identification of tau as a subunit of the DNA polymerase III holoenzyme. |
Native organism |
|
Tth Pol III |
Eubacterium |
C
|
DNA polymerase III holoenzyme from Thermus thermophilus identification, expression, purification of components, and use to reconstitute a processive replicase. |
Cloned in E. coli |
|
Human Pol lamba |
Eukaryote |
X
|
Over-expression of human DNA polymerase lambda in E. coli and characterization of the recombinant enzyme. |
Cloned in E. coli |
|
Human Pol lamba |
Eukaryote |
X
|
DNA polymerase lambda, a novel DNA repair enzyme in human cells. |
Cloned in E. coli |
|
Human Pol mu |
Eukaryote |
X
|
DNA polymerase mu (Pol mu), homologous to TdT, could act as a DNA mutator in eukaryotic cells. |
Cloned in E. coli |
|
Human Pol mu |
Eukaryote |
X
|
Highly frequent frameshift DNA synthesis by human DNA polymerase mu. |
Cloned in yeast |
|
Phi29 |
Virus/Phage |
B
|
Initiation of phage phi 29 DNA replication in vitro: formation of a covalent complex between the terminal protein, p3, and 5'-dAMP. |
Cloned in E. coli |
|
Phi29 |
Virus/Phage |
B
|
TempliPhi, phi29 DNA polymerase based rolling circle amplification of templates for DNA sequencing. |
Native organism |
|
Phi29 |
Virus/Phage |
B
|
Functional characterization of highly processive protein-primed DNA polymerases from phages Nf and GA-1, endowed with a potent strand displacement capacity. |
Cloned in E. coli |
|
Phi29 |
Virus/Phage |
B
|
Processive proofreading and the spatial relationship between polymerase and exonuclease active sites of bacteriophage phi29 DNA polymerase. |
Cloned in E. coli |
|
Phi29 |
Virus/Phage |
B
|
Characterization and purification of a phage phi 29-encoded DNA polymerase required for the initiation of replication. |
Cloned in E. coli |
|
PGBD Pol I |
Archaeon |
B
|
Incorporation of reporter-labeled nucleotides by DNA polymerases. |
Unspecified |
|
Bst |
Eubacterium |
A
|
DNA polymerase from mesophilic and thermophilic bacteria. III. Lack of fidelity in the replication of synthetic polydeoxyribonucleotides by DNA polymerase from Bacillus licheniformis and Bacillus stearothermophilus. |
Native organism |
|
Bst |
Eubacterium |
A
|
Thermostable Bst DNA polymerase I lacks a 3'-->5' proofreading exonuclease activity. |
Native organism |
|
Bsu (large fragment) |
Eubacterium |
?
|
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. XV. PURIFICATION AND PROPERTIES OF A POLYMERASE FROM BACILLUS SUBTILIS. |
Native organism |
|
MMuLV RT |
Virus/Phage |
RT
|
Parameters that influence processive synthesis and site-specific termination by human immunodeficiency virus reverse transcriptase on RNA and DNA templates. |
Native organism |
|
Bst LF |
Eubacterium |
A
|
Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations. |
Cloned in E. coli |
|
Bst LF |
Eubacterium |
A
|
Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. |
Cloned in E. coli |
|
Bst LF |
Eubacterium |
A
|
Thermostable Bst DNA polymerase I lacks a 3'-->5' proofreading exonuclease activity. |
Cloned in E. coli |
|
Bsu |
Eubacterium |
?
|
DNA polymerase III gene of Bacillus subtilis. |
Cloned in E. coli |
|
KF Y766S |
Eubacterium |
A
|
Identification of residues critical for the polymerase activity of the Klenow fragment of DNA polymerase I from Escherichia coli. |
Cloned in E. coli |
|
9egN D141A/D143A |
Archaeon |
B
|
Crystal structure of a pol alpha family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. 9 degrees N-7. |
Cloned in E. coli |
|
AMV |
Virus/Phage |
RT
|
RNA-dependent DNA polymerase activity of RNA tumor virus. VI. Processive mode of action of avian myeloblastosis virus polymerase. |
Native organism |
|
AMV |
Virus/Phage |
RT
|
Mechanism of carcinogenesis by RNA tumor viruses. 3. Formation of RNA, DNA complex and duplex DNA molecules by the DNA polymerase (s) of avian myeloblastosis virus. |
Native organism |
|
AMV |
Virus/Phage |
RT
|
On the fidelity of DNA replication. Lack of exodeoxyribonuclease activity and error-correcting function in avian myeloblastosis virus DNA polymerase. |
Native organism |
|
AMV |
Virus/Phage |
RT
|
Parameters that influence processive synthesis and site-specific termination by human immunodeficiency virus reverse transcriptase on RNA and DNA templates. |
Native organism |
|
T2 |
Virus/Phage |
B
|
Separation of deoxyribo-oligonucleotidases induced by infection with bacteriophage T2. |
Cloned in E. coli |
|
pB6B15.23 |
Unknown |
?
|
Purification and characterization of murine retroviral reverse transcriptase expressed in Escherichia coli. |
Cloned in E. coli |
|
phi29 T434N |
Virus/Phage |
B
|
Primer-terminus stabilization at the psi 29 DNA polymerase active site. Mutational analysis of conserved motif TX2GR. |
Cloned in E. coli |
|
phi29 R438I |
Virus/Phage |
B
|
Primer-terminus stabilization at the psi 29 DNA polymerase active site. Mutational analysis of conserved motif TX2GR. |
Cloned in E. coli |
|
phi29 A437G |
Virus/Phage |
B
|
Primer-terminus stabilization at the psi 29 DNA polymerase active site. Mutational analysis of conserved motif TX2GR. |
Cloned in E. coli |
|
phi29 R438K |
Virus/Phage |
B
|
Primer-terminus stabilization at the psi 29 DNA polymerase active site. Mutational analysis of conserved motif TX2GR. |
Cloned in E. coli |
|
Bli DNA polymerase |
Eubacterium |
A
|
DNA polymerase from mesophilic and thermophilic bacteria. III. Lack of fidelity in the replication of synthetic polydeoxyribonucleotides by DNA polymerase from Bacillus licheniformis and Bacillus stearothermophilus. |
Native organism |
|
Bst LF (D329A) |
Eubacterium |
A
|
Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations. |
Cloned in E. coli |
|
Bst LF (D598A) |
Eubacterium |
A
|
Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations. |
Cloned in E. coli |
|
Bst LF (D329AD598A) |
Eubacterium |
A
|
Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations. |
Cloned in E. coli |
|
Human Pol alpha |
Eukaryote |
B
|
Fidelity of DNA synthesis catalyzed by human DNA polymerase alpha and HIV-1 reverse transcriptase: effect of reaction pH. |
Insect cells |
|
Human Pol alpha |
Eukaryote |
B
|
Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III. |
Cloned in E. coli |
|
Human Pol alpha |
Eukaryote |
B
|
Human DNA polymerases alpha and beta are able to incorporate anti-HIV deoxynucleotides into DNA. |
Native organism |
|
T7 (purified without EDTA) |
Virus/Phage |
A
|
Two forms of the DNA polymerase of bacteriophage T7. |
Cloned in E. coli |
|
T7 (purified without EDTA) |
Virus/Phage |
A
|
Characterization of strand displacement synthesis catalyzed by bacteriophage T7 DNA polymerase. |
Native organism |
|
Eco Pol II |
Eubacterium |
B
|
Processive DNA synthesis by DNA polymerase II mediated by DNA polymerase III accessory proteins. |
Native organism |
|
Human Pol delta |
Eukaryote |
B
|
Production of recombinant human DNA polymerase delta in a Bombyx mori bioreactor. |
Insect cells |
|
Human Pol epsilon |
Eukaryote |
B
|
Characterization of a large form of DNA polymerase delta from HeLa cells that is insensitive to proliferating cell nuclear antigen. |
Native organism |
|
Human Pol epsilon |
Eukaryote |
B
|
Further characterization of HeLa DNA polymerase epsilon. |
Native organism |
|
Sce Pol eta |
Eukaryote |
Y
|
Fidelity and processivity of Saccharomyces cerevisiae DNA polymerase eta. |
Cloned in yeast |
|
Sce Pol alpha |
Eukaryote |
B
|
Purification and characterization of the 180- and 86-kilodalton subunits of the Saccharomyces cerevisiae DNA primase-DNA polymerase protein complex. The 180-kilodalton subunit has both DNA polymerase and 3'----5'-exonuclease activities. |
Cloned in yeast |
|
Sce Pol alpha |
Eukaryote |
B
|
Distinct function of conserved amino acids in the fingers of Saccharomyces cerevisiae DNA polymerase alpha. |
Cloned in yeast |
|
HHV1 |
Virus/Phage |
B
|
The crystal structure of an unusual processivity factor, herpes simplex virus UL42, bound to the C terminus of its cognate polymerase. |
Cloned in E. coli |
|
HIV RT K65R |
Virus/Phage |
RT
|
The K65R mutation confers increased DNA polymerase processivity to HIV-1 reverse transcriptase. |
Cloned in E. coli |
|
Sce Pol delta |
Eukaryote |
B
|
The 3' to 5' exonuclease activity located in the DNA polymerase delta subunit of Saccharomyces cerevisiae is required for accurate replication. |
Cloned in yeast |
|
Sce Pol delta |
Eukaryote |
B
|
Structure and processivity of two forms of Saccharomyces cerevisiae DNA polymerase delta. |
Native organism |
|
phi29 D332Y |
? |
?
|
An aspartic acid residue in TPR-1, a specific region of protein-priming DNA polymerases, is required for the functional interaction with primer terminal protein. |
Cloned in E. coli |
|
HIV2 RT |
Virus/Phage |
RT
|
Fidelity of the reverse transcriptase of human immunodeficiency virus type 2. |
Cloned in E. coli |
|
Bsu Pol X |
Eubacterium |
X
|
Characterization of a Bacillus subtilis 64-kDa DNA polymerase X potentially involved in DNA repair. |
Cloned in E. coli |
|
Human Pol theta |
Eukaryote |
A
|
The human DINB1 gene encodes the DNA polymerase Poltheta. |
Cloned in yeast |
|
Pol eta Y52E |
Eukaryote |
Y
|
Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. |
Cloned in yeast |
|
Pol eta Y52D |
Eukaryote |
Y
|
Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. |
Cloned in yeast |
|
Pol eta Y52H |
Eukaryote |
Y
|
Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. |
Cloned in yeast |
|
Pol eta Y52F |
Eukaryote |
Y
|
Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. |
Cloned in yeast |
|
Pol eta Y52A |
Eukaryote |
Y
|
Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. |
Cloned in yeast |
|
Sce Pol alpha Y951P |
Eukaryote |
B
|
Distinct function of conserved amino acids in the fingers of Saccharomyces cerevisiae DNA polymerase alpha. |
Cloned in yeast |
|
Tgu |
Archaeon |
B
|
Characterization and PCR optimization of the thermostable family B DNA polymerase from Thermococcus guaymasensis |
Cloned in E. coli |
|
T7 (exo-) |
Virus/Phage |
A
|
Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant. |
Cloned in E. coli |
|
Eco Pol III' |
Eubacterium |
C
|
Purification and characterization of DNA polymerase III'. Identification of tau as a subunit of the DNA polymerase III holoenzyme. |
Native organism |
|
Vaccinia Virus Pol |
Virus/Phage |
B
|
Characterization of a processive form of the vaccinia virus DNA polymerase. |
Native organism |
|
Dme Pol delta |
Eukaryote |
B
|
Drosophila DNA polymerase delta. Purification and characterization. |
Native organism |
|
ASFV pol X |
Virus/Phage |
X
|
Characterization of an African swine fever virus 20-kDa DNA polymerase involved in DNA repair. |
Cloned in E. coli |
|
ASFV pol X |
Virus/Phage |
X
|
Solution structure of a viral DNA polymerase X and evidence for a mutagenic function. |
Cloned in E. coli |
|
Stoffel fragment |
Eubacterium |
A
|
High-level expression, purification, and enzymatic characterization of full-length Thermus aquaticus DNA polymerase and a truncated form deficient in 5' to 3' exonuclease activity. |
Cloned in E. coli |
|
Eco Pol I* |
Eubacterium |
A
|
Characterization of DNA polymerase I*, a form of DNA polymerase I found in Escherichia coli expressing SOS functions. |
Native organism |
|
SsoDpo1 |
Archaeon |
B
|
A trimeric DNA polymerase complex increases the native replication processivity. |
Cloned in E. coli |
|
SsoDpo1 |
Archaeon |
B
|
Strand annealing and terminal transferase activities of a B-family DNA polymerase. |
Cloned in E. coli |
|
Pol Kappa (exo-) |
Eukaryote |
Y
|
Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene. |
Cloned in E. coli |
|
T7 (no thioreoxin) |
Virus/Phage |
A
|
Escherichia coli thioredoxin confers processivity on the DNA polymerase activity of the gene 5 protein of bacteriophage T7. |
Cloned in E. coli |
|
A |
Virus/Phage |
B
|
Processive proofreading by the adenovirus DNA polymerase. Association with the priming protein reduces exonucleolytic degradation. |
Insect cells |
|
Nf |
Virus/Phage |
B
|
Functional characterization of highly processive protein-primed DNA polymerases from phages Nf and GA-1, endowed with a potent strand displacement capacity. |
Native organism |
|
GA-1 |
Virus/Phage |
B
|
Functional characterization of highly processive protein-primed DNA polymerases from phages Nf and GA-1, endowed with a potent strand displacement capacity. |
Native organism |
|
RB69-SSO-F6 |
Virus/Phage |
?
|
Structure and enzymatic properties of a chimeric bacteriophage RB69 DNA polymerase and single-stranded DNA binding protein with increased processivity. |
Cloned in E. coli |
|
Sce Pol delta* |
Eukaryote |
B
|
Structure and processivity of two forms of Saccharomyces cerevisiae DNA polymerase delta. |
Native organism |
|
AcNPV |
Virus/Phage |
B
|
Autographa californica nuclear polyhedrosis virus DNA polymerase: measurements of processivity and strand displacement. |
Insect cells |
|
VZV Pol I |
Virus/Phage |
B
|
Purification and characterization of varicella-zoster virus-induced DNA polymerase. |
Native organism |
|
Pab Pol I |
Archaeon |
B
|
PCR performance of the highly thermostable proof-reading B-type DNA polymerase from Pyrococcus abyssi. |
Cloned in E. coli |
|
FeLV RT |
Virus/Phage |
RT
|
Comparison of DNA polymerase activities between recombinant feline immunodeficiency and leukemia virus reverse transcriptases. |
Cloned in E. coli |
|
FIV RT |
Virus/Phage |
RT
|
Comparison of DNA polymerase activities between recombinant feline immunodeficiency and leukemia virus reverse transcriptases. |
Cloned in E. coli |
|
MDV |
Virus/Phage |
B
|
Identification and characterization of a Marek's disease virus gene encoding DNA polymerase. |
Cloned in E. coli |
|
Chicken Pol beta |
Eukaryote |
X
|
The mutational specificity of DNA polymerase-beta during in vitro DNA synthesis. Production of frameshift, base substitution, and deletion mutations. |
Native organism |
|
MutD5 Pol III |
Eubacterium |
C
|
The base substitution and frameshift fidelity of Escherichia coli DNA polymerase III holoenzyme in vitro. |
Native organism |
|
Mouse Pol eta |
Eukaryote |
Y
|
Error rate and specificity of human and murine DNA polymerase eta. |
Insect cells |
|
Human Pol nu |
Eukaryote |
A
|
A unique error signature for human DNA polymerase nu. |
Cloned in E. coli |
|
Bovine pol elta |
Eukaryote |
B
|
Further studies on calf thymus DNA polymerase delta purified to homogeneity by a new procedure. |
Native organism |
|
Poc Pol I |
Archaeon |
B
|
The hyperthermophilic archaeon Pyrodictium occultum has two alpha-like DNA polymerases. |
Cloned in E. coli |
|
Poc Pol II |
Archaeon |
B
|
The hyperthermophilic archaeon Pyrodictium occultum has two alpha-like DNA polymerases. |
Cloned in E. coli |
|
Eco Pol I - Small Fragment |
Eubacterium |
Non Pol
|
Coordination between the polymerase and 5'-nuclease components of DNA polymerase I of Escherichia coli. |
Cloned in E. coli |
|
Klenow Fragment D424A |
Eubacterium |
A
|
Coordination between the polymerase and 5'-nuclease components of DNA polymerase I of Escherichia coli. |
Cloned in E. coli |
|
Tcr pol eta |
? |
?
|
Cloning and characterization of DNA polymerase eta from Trypanosoma cruzi: roles for translesion bypass of oxidative damage. |
Cloned in E. coli |
|
Ath pol eta |
Eukaryote |
Y
|
Arabidopsis thaliana Y-family DNA polymerase eta catalyses translesion synthesis and interacts functionally with PCNA2. |
Cloned in E. coli |
|
Phi29 D12AD66A |
Virus/Phage |
B
|
Processive proofreading and the spatial relationship between polymerase and exonuclease active sites of bacteriophage phi29 DNA polymerase. |
Cloned in E. coli |
|
Human Pol gamma D198AG200A |
Eukaryote |
A
|
Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers. |
Insect cells |
|