show help

Results for property: 3-5' exo

Detailed Results for Property

Use this page to examine all the the polymerases and references referring to the property: 3-5' exo.

Conflicts: Polbase presents all the values that have been entered, including those that may conflict with each other. Consider the reported context, or refer to the reference for more details.

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.

Polymerase Kingdom Family Reference Result Context
Klenow fragment Eubacterium A The 3'-5' exonuclease of DNA polymerase I of Escherichia coli: contribution of each amino acid at the active site to the reaction. Yes
RB69 G258S Virus/Phage B Use of 2-aminopurine fluorescence to study the role of the beta hairpin in the proofreading pathway catalyzed by the phage T4 and RB69 DNA polymerases. No
RB69 beta hairpin- Virus/Phage B Use of 2-aminopurine fluorescence to study the role of the beta hairpin in the proofreading pathway catalyzed by the phage T4 and RB69 DNA polymerases. No
RB69 D222AD327A Virus/Phage B Use of 2-aminopurine fluorescence to study the role of the beta hairpin in the proofreading pathway catalyzed by the phage T4 and RB69 DNA polymerases. No
RB69 G258SD222A/D237A Virus/Phage B Use of 2-aminopurine fluorescence to study the role of the beta hairpin in the proofreading pathway catalyzed by the phage T4 and RB69 DNA polymerases. No
RB69 D222AD327A beta hairpin- Virus/Phage B Use of 2-aminopurine fluorescence to study the role of the beta hairpin in the proofreading pathway catalyzed by the phage T4 and RB69 DNA polymerases. No
T4 D219A Virus/Phage B Probing DNA polymerase-DNA interactions: examining the template strand in exonuclease complexes using 2-aminopurine fluorescence and acrylamide quenching. No
Taq pol I Eubacterium A Fidelity of Thermococcus litoralis DNA polymerase (Vent) in PCR determined by denaturing gradient gel electrophoresis. No
T4 W213S Virus/Phage B DNA polymerase proofreading: active site switching catalyzed by the bacteriophage T4 DNA polymerase. No
T4 D112AE114A Virus/Phage B DNA polymerase proofreading: active site switching catalyzed by the bacteriophage T4 DNA polymerase. No
Vent (exo-) Archaeon B Fidelity of DNA synthesis by the Thermococcus litoralis DNA polymerase--an extremely heat stable enzyme with proofreading activity. No
Sequenase Virus/Phage A Fidelity of Thermococcus litoralis DNA polymerase (Vent) in PCR determined by denaturing gradient gel electrophoresis. No
Vent Archaeon B Characterization of a DNA polymerase from the hyperthermophile archaea Thermococcus litoralis. Vent DNA polymerase, steady state kinetics, thermal stability, processivity, strand displacement, and exonuclease activities. Yes
Replinase Unknown ? Fidelity of DNA synthesis by the Thermococcus litoralis DNA polymerase--an extremely heat stable enzyme with proofreading activity. No
T7 Virus/Phage A Fidelity of DNA synthesis by the Thermococcus litoralis DNA polymerase--an extremely heat stable enzyme with proofreading activity. Yes
Vent Archaeon B Fidelity of DNA synthesis by the Thermococcus litoralis DNA polymerase--an extremely heat stable enzyme with proofreading activity. Yes
T7 (purified without EDTA) Virus/Phage A Characterization of strand displacement synthesis catalyzed by bacteriophage T7 DNA polymerase. Yes
Bst Eubacterium A Thermostable Bst DNA polymerase I lacks a 3'-->5' proofreading exonuclease activity. No
9egN Archaeon B Cloning of thermostable DNA polymerases from hyperthermophilic marine Archaea with emphasis on Thermococcus sp. 9 degrees N-7 and mutations affecting 3'-5' exonuclease activity. Yes
Bsu (large fragment) Eubacterium ? ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. XV. PURIFICATION AND PROPERTIES OF A POLYMERASE FROM BACILLUS SUBTILIS. No
Vent Archaeon B Fidelity of Thermococcus litoralis DNA polymerase (Vent) in PCR determined by denaturing gradient gel electrophoresis. Yes
T7 Virus/Phage A Deoxyribonucleic acid polymerase of bacteriophage T7. Purification and properties of the phage-encoded subunit, the gene 5 protein. Yes
T7 Virus/Phage A Characterization of bacteriophage T7 DNA polymerase purified to homogeneity by antithioredoxin immunoadsorbent chromatography. Yes
T7 (purified without EDTA) Virus/Phage A Two forms of the DNA polymerase of bacteriophage T7. Yes
T7 Virus/Phage A T7-induced DNA polymerase. Requirement for thioredoxin sulfhydryl groups. Yes
T7 Virus/Phage A Characterization of strand displacement synthesis catalyzed by bacteriophage T7 DNA polymerase. Yes
Taq pol I Eubacterium A Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase. No
Eco Pol I Eubacterium A The steady state kinetic parameters and non-processivity of Escherichia coli deoxyribonucleic acid polymerase I. Yes
T7 Virus/Phage A T7-induced DNA polymerase. Characterization of associated exonuclease activities and resolution into biologically active subunits. Yes
T7 Virus/Phage A Deoxyribonucleic acid polymerase of bacteriophage T7. Yes
Phi29 Virus/Phage B The bacteriophage phi 29 DNA polymerase, a proofreading enzyme. Yes
Klenow (exo-) Eubacterium A Effect of reaction pH on the fidelity and processivity of exonuclease-deficient Klenow polymerase. No
Klenow fragment Eubacterium A Identification of residues critical for the polymerase activity of the Klenow fragment of DNA polymerase I from Escherichia coli. Yes
phi29 T434N Virus/Phage B Primer-terminus stabilization at the psi 29 DNA polymerase active site. Mutational analysis of conserved motif TX2GR. Yes
phi29 R438I Virus/Phage B Primer-terminus stabilization at the psi 29 DNA polymerase active site. Mutational analysis of conserved motif TX2GR. Yes
phi29 R438K Virus/Phage B Primer-terminus stabilization at the psi 29 DNA polymerase active site. Mutational analysis of conserved motif TX2GR. Yes
phi29 A437G Virus/Phage B Primer-terminus stabilization at the psi 29 DNA polymerase active site. Mutational analysis of conserved motif TX2GR. Yes
Bst LF Eubacterium A Thermostable Bst DNA polymerase I lacks a 3'-->5' proofreading exonuclease activity. No
Klenow fragment Eubacterium A The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I. Yes
KF D424A Eubacterium A The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I. No
KF D355AE357A Eubacterium A The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I. No
KF(515-928) Eubacterium A The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I. No
AMV Virus/Phage RT On the fidelity of DNA replication. Lack of exodeoxyribonuclease activity and error-correcting function in avian myeloblastosis virus DNA polymerase. No
PGBD Pol I Archaeon B Fidelity and predominant mutations produced by deep vent wild-type and exonuclease-deficient DNA polymerases during in vitro DNA amplification. Yes
Bsu Eubacterium ? DNA polymerase III gene of Bacillus subtilis. Yes
Pfu Archaeon B High-fidelity amplification using a thermostable DNA polymerase isolated from Pyrococcus furiosus. Yes
Human Pol eta Eukaryote Y Low fidelity DNA synthesis by human DNA polymerase-eta. No
DTok Archaeon B Crystal structure of an archaebacterial DNA polymerase. Yes
EBV Pol Virus/Phage B Characterization of 3'-to 5'-exonuclease activity associated with Epstein-Barr virus DNA polymerase. Yes
Human Pol gamma Eukaryote A Exonucleolytic proofreading by a mammalian DNA polymerase. Yes
KOD1 Archaeon B Characterization of DNA polymerase from Pyrococcus sp. strain KOD1 and its application to PCR. Yes
Rat Pol beta Eukaryote X Autonomous 3'-->5' exonucleases can proofread for DNA polymerase beta from rat liver. Yes
Human Pol delta Eukaryote B The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability. Yes
Eco Pol II Eubacterium B Proofreading-defective DNA polymerase II increases adaptive mutation in Escherichia coli. Yes
Eco Pol II exo- Eubacterium B Proofreading-defective DNA polymerase II increases adaptive mutation in Escherichia coli. No
Eco Pol III Eubacterium C Fidelity of Escherichia coli DNA polymerase III holoenzyme. The effects of beta, gamma complex processivity proteins and epsilon proofreading exonuclease on nucleotide misincorporation efficiencies. Yes
Human Pol alpha Eukaryote B Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerases. No
Human Pol epsilon Eukaryote B Subunit protein-affinity isolation of Drosophila DNA polymerase catalytic subunit. Yes
Human Pol iota Eukaryote Y Preferential incorporation of G opposite template T by the low-fidelity human DNA polymerase iota. No
Pol eta Y52E Eukaryote Y Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. No
Human Pol mu Eukaryote X DNA polymerase mu (Pol mu), homologous to TdT, could act as a DNA mutator in eukaryotic cells. No
Eco Pol IV Eubacterium Y The dinB gene encodes a novel E. coli DNA polymerase, DNA pol IV, involved in mutagenesis. No
RB69 Virus/Phage B Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family. Yes
Tth Pol I Eubacterium A Reverse transcription and DNA amplification by a Thermus thermophilus DNA polymerase. No
Tth Pol III Eubacterium C DNA polymerase III holoenzyme from Thermus thermophilus identification, expression, purification of components, and use to reconstitute a processive replicase. Yes
Tne pol Eubacterium A Domain exchange: chimeras of Thermus aquaticus DNA polymerase, Escherichia coli DNA polymerase I and Thermotoga neapolitana DNA polymerase. Yes
Thermo JDF-3 pol Archaeon B Efficient and high fidelity incorporation of dye-terminators by a novel archaeal DNA polymerase mutant. Yes
TGO Archaeon B Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius. Yes
Terminal Transferase Unknown ? Characterization of the homopolymer tailing reaction catalyzed by terminal deoxynucleotidyl transferase. Implications for the cloning of cDNA. No
Streptococcus pneumoniae Pol I Eubacterium A Characterization of the polA gene of Streptococcus pneumoniae and comparison of the DNA polymerase I it encodes to homologous enzymes from Escherichia coli and phage T7. Yes
T2 Virus/Phage B Separation of deoxyribo-oligonucleotidases induced by infection with bacteriophage T2. No
T5 Virus/Phage A Exonuclease associated with bacteriophage T5-Induced DNA polymerase. Yes
T4 Virus/Phage B On the exonuclease activity of phage T4 deoxyribonucleic acid polymerase. Yes
Streptococcus pneumoniae Pol I Eubacterium A The 5' to 3' exonuclease activity of DNA polymerase I is essential for Streptococcus pneumoniae. No
Streptococcus pneumoniae Pol I Eubacterium A Streptococcus pneumoniae DNA polymerase I lacks 3'-to-5' exonuclease activity: localization of the 5'-to-3' exonucleolytic domain. No
Sce Pol delta Eukaryote B The 3' to 5' exonuclease activity located in the DNA polymerase delta subunit of Saccharomyces cerevisiae is required for accurate replication. Yes
phi29 D332Y ? ? An aspartic acid residue in TPR-1, a specific region of protein-priming DNA polymerases, is required for the functional interaction with primer terminal protein. Yes
Human Pol beta Eukaryote X Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism. No
T4 Virus/Phage B Isolation, characterization, and kinetic properties of truncated forms of T4 DNA polymerase that exhibit 3'-5' exonuclease activity. Yes
Pol eta Y52F Eukaryote Y Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. No
Pol eta Y52A Eukaryote Y Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. No
Bsu Pol X Eubacterium X Characterization of a Bacillus subtilis 64-kDa DNA polymerase X potentially involved in DNA repair. Yes
T4 Virus/Phage B On the role of deoxyribonucleic acid polymerase in determining mutation rates. Characterization of the defect in the T4 deoxyribonucleic acid polymerase caused by the ts L88 mutation. Yes
T4 Virus/Phage B The slow dissociation of the T4 DNA polymerase holoenzyme when stalled by nucleotide omission. An indication of a highly processive enzyme. Unspecified
Human Pol beta Eukaryote X Expression of human DNA polymerase beta in Escherichia coli and characterization of the recombinant enzyme. No
Human Pol gamma Eukaryote A Characterization of the native and recombinant catalytic subunit of human DNA polymerase gamma: identification of residues critical for exonuclease activity and dideoxynucleotide sensitivity. Yes
Human Pol alpha Eukaryote B Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. No
Human Pol delta Eukaryote B Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. Yes
Human Pol epsilon Eukaryote B Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. Yes
Vent Archaeon B Incorporation of reporter-labeled nucleotides by DNA polymerases. Yes
Taq pol I Eubacterium A Incorporation of reporter-labeled nucleotides by DNA polymerases. No
PGBD Pol I Archaeon B Incorporation of reporter-labeled nucleotides by DNA polymerases. Yes
Pfu Archaeon B Incorporation of reporter-labeled nucleotides by DNA polymerases. Yes
T4 Virus/Phage B Incorporation of reporter-labeled nucleotides by DNA polymerases. Yes
Eco Pol I Eubacterium A Incorporation of reporter-labeled nucleotides by DNA polymerases. No
Sce Pol alpha Eukaryote B Purification and characterization of the 180- and 86-kilodalton subunits of the Saccharomyces cerevisiae DNA primase-DNA polymerase protein complex. The 180-kilodalton subunit has both DNA polymerase and 3'----5'-exonuclease activities. Yes
KOD1 Archaeon B Catalyzing "hot" reactions: enzymes from hyperthermophilic Archaea. Yes
T7 (exo-) Virus/Phage A Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant. No
T7 Virus/Phage A Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant. Yes
KF D424A Eubacterium A The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I. No
Vaccinia Virus Pol Virus/Phage B Characterization of a processive form of the vaccinia virus DNA polymerase. Yes
Dme Pol delta Eukaryote B Drosophila DNA polymerase delta. Purification and characterization. Yes
Eco Pol IV Eubacterium Y The beta clamp targets DNA polymerase IV to DNA and strongly increases its processivity. No
Human Pol gamma Eukaryote A Expression, purification, and initial kinetic characterization of the large subunit of the human mitochondrial DNA polymerase. Yes
ASFV pol X Virus/Phage X Characterization of an African swine fever virus 20-kDa DNA polymerase involved in DNA repair. No
Human Pol eta Eukaryote Y Pre-Steady-State Kinetic Analysis of Truncated and Full-Length Saccharomyces cerevisiae DNA Polymerase Eta. Yes
Human Pol kappa Eukaryote Y Purification and characterization of pol kappa, a DNA polymerase encoded by the human DINB1 gene. No
T7 Virus/Phage A Single-molecule studies of the effect of template tension on T7 DNA polymerase activity. Yes
Bst LF Eubacterium A Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. No
Taq pol I Eubacterium A Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. No
Klenow fragment Eubacterium A Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. Yes
T4 Virus/Phage B A single mutation in bacteriophage T4 DNA polymerase (A737V, tsL141) decreases its processivity as a polymerase and increases its processivity as a 3'-->5' exonuclease. Yes
T4 A737V Virus/Phage B A single mutation in bacteriophage T4 DNA polymerase (A737V, tsL141) decreases its processivity as a polymerase and increases its processivity as a 3'-->5' exonuclease. Yes
T4 L771F Virus/Phage B A single mutation in bacteriophage T4 DNA polymerase (A737V, tsL141) decreases its processivity as a polymerase and increases its processivity as a 3'-->5' exonuclease. Yes
Eco Pol I Eubacterium A Characterization of DNA polymerase I*, a form of DNA polymerase I found in Escherichia coli expressing SOS functions. Yes
Eco Pol I* Eubacterium A Characterization of DNA polymerase I*, a form of DNA polymerase I found in Escherichia coli expressing SOS functions. Yes
Human Pol eta Eukaryote Y Pre-Steady-State Kinetic Analysis of Truncated and Full-Length Saccharomyces cerevisiae DNA Polymerase Eta. Yes
Human Pol kappa Eukaryote Y Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene. No
Pol Kappa (exo-) Eukaryote Y Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene. No
T7 Virus/Phage A The thioredoxin binding domain of bacteriophage T7 DNA polymerase confers processivity on Escherichia coli DNA polymerase I. Yes
HIV RT Virus/Phage RT Human immunodeficiency virus 1 reverse transcriptase. Template binding, processivity, strand displacement synthesis, and template switching. No
Tae pol A Eukaryote B Mammalian proliferating cell nuclear antigen stimulates the processivity of two wheat embryo DNA polymerases. No
Tae pol B Eukaryote ? Mammalian proliferating cell nuclear antigen stimulates the processivity of two wheat embryo DNA polymerases. Yes
Tae pol CI Eukaryote ? Mammalian proliferating cell nuclear antigen stimulates the processivity of two wheat embryo DNA polymerases. No
Tae pol CII Eubacterium ? Mammalian proliferating cell nuclear antigen stimulates the processivity of two wheat embryo DNA polymerases. No
Phi29 Virus/Phage B Functional characterization of highly processive protein-primed DNA polymerases from phages Nf and GA-1, endowed with a potent strand displacement capacity. Yes
GA-1 Virus/Phage B Functional characterization of highly processive protein-primed DNA polymerases from phages Nf and GA-1, endowed with a potent strand displacement capacity. Yes
Nf Virus/Phage B Functional characterization of highly processive protein-primed DNA polymerases from phages Nf and GA-1, endowed with a potent strand displacement capacity. Yes
Human Pol gamma Eukaryote A A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase. Yes
Phi29 Virus/Phage B A specific subdomain in phi29 DNA polymerase confers both processivity and strand-displacement capacity. Yes
phi29 (-TPR2) Virus/Phage B A specific subdomain in phi29 DNA polymerase confers both processivity and strand-displacement capacity. Yes
Human Pol gamma Eukaryote A The mitochondrial p55 accessory subunit of human DNA polymerase gamma enhances DNA binding, promotes processive DNA synthesis, and confers N-ethylmaleimide resistance. Yes
T7 Virus/Phage A Error-prone replication of repeated DNA sequences by T7 DNA polymerase in the absence of its processivity subunit. Yes
Phi29 Virus/Phage B TempliPhi, phi29 DNA polymerase based rolling circle amplification of templates for DNA sequencing. Yes
Eco Pol II Eubacterium B Purification and DNA synthesis in cell-free extracts: properties of DNA polymerase II. Unspecified
Eco Pol III Eubacterium C Processive DNA synthesis by DNA polymerase II mediated by DNA polymerase III accessory proteins. Yes
Eco Pol I Eubacterium A Processive DNA synthesis by DNA polymerase II mediated by DNA polymerase III accessory proteins. Yes
Eco Pol II Eubacterium B Processive DNA synthesis by DNA polymerase II mediated by DNA polymerase III accessory proteins. Yes
Phi29 Virus/Phage B Functional importance of bacteriophage phi29 DNA polymerase residue Tyr148 in primer-terminus stabilisation at the 3'-5' exonuclease active site. Yes
Pfu Archaeon B The 3'-5' proofreading exonuclease of archaeal family-B DNA polymerase hinders the copying of template strand deaminated bases. Yes
A Virus/Phage B Properties of the adenovirus DNA polymerase. Yes
Eco Pol I Eubacterium A Thermostable DNA polymerases. Yes
Human Pol epsilon Eukaryote B Evolution of DNA polymerases: an inactivated polymerase-exonuclease module in Pol epsilon and a chimeric origin of eukaryotic polymerases from two classes of archaeal ancestors. Yes
Eco Pol II Eubacterium B Thermostable DNA polymerases. Yes
Eco Pol III Eubacterium C Thermostable DNA polymerases. Yes
Human Pol alpha Eukaryote B Thermostable DNA polymerases. No
Human Pol beta Eukaryote X Thermostable DNA polymerases. No
Human Pol delta Eukaryote B Thermostable DNA polymerases. Yes
Human Pol epsilon Eukaryote B Thermostable DNA polymerases. Yes
T7 Virus/Phage A Thermostable DNA polymerases. Yes
Taq pol I Eubacterium A Thermostable DNA polymerases. No
Human Pol lamba Eukaryote X DNA polymerase lambda, a novel DNA repair enzyme in human cells. No
Tgu Archaeon B Characterization and PCR optimization of the thermostable family B DNA polymerase from Thermococcus guaymasensis Yes
Sce Pol alpha Eukaryote B Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme. No
Sce Pol II Eukaryote B Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme. Yes
Sce Pol II* Eukaryote ? Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme. Yes
Sce Pol III Eukaryote C Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme. Yes
Human Pol gamma Eukaryote A Characterization of the native and recombinant catalytic subunit of human DNA polymerase gamma: identification of residues critical for exonuclease activity and dideoxynucleotide sensitivity. Yes
Human Pol gamma Eukaryote A Thermostable DNA polymerases. Yes
Klenow (exo-) Eubacterium A Kinetics of DNA polymerase I (Klenow fragment exo-) activity on damaged DNA templates: effect of proximal and distal template damage on DNA synthesis. No
Deep Vent (exo-) Archaeon B Unnatural imidazopyridopyrimidine:naphthyridine base pairs: selective incorporation and extension reaction by Deep Vent (exo- ) DNA polymerase. No
HHV1 YD12 Virus/Phage ? Finger domain mutation affects enzyme activity, DNA replication efficiency, and fidelity of an exonuclease-deficient DNA polymerase of herpes simplex virus type 1. No
HHV1 L774F Virus/Phage ? Finger domain mutation affects enzyme activity, DNA replication efficiency, and fidelity of an exonuclease-deficient DNA polymerase of herpes simplex virus type 1. No
HHV1 Virus/Phage B Finger domain mutation affects enzyme activity, DNA replication efficiency, and fidelity of an exonuclease-deficient DNA polymerase of herpes simplex virus type 1. Yes
TGO Archaeon B The 3'-5' proofreading exonuclease of archaeal family-B DNA polymerase hinders the copying of template strand deaminated bases. Yes
Klenow fragment Eubacterium A Identification of a new motif required for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I (Klenow fragment): the RRRY motif is necessary for the binding of single-stranded DNA substrate and the template strand of the mismatched duplex. Yes
Bsu Pol X Eubacterium X Editing of misaligned 3'-termini by an intrinsic 3'-5' exonuclease activity residing in the PHP domain of a family X DNA polymerase. Yes
Klenow (exo-) Eubacterium A Synthesis of novel poly(dG)-poly(dG)-poly(dC) triplex structure by Klenow exo- fragment of DNA polymerase I. No
Klenow fragment Eubacterium A Synthesis of novel poly(dG)-poly(dG)-poly(dC) triplex structure by Klenow exo- fragment of DNA polymerase I. Yes
Klenow fragment Eubacterium A Contribution of polar residues of the J-helix in the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I (Klenow fragment): Q677 regulates the removal of terminal mismatch. Yes
Klenow (exo-) Eubacterium A In vitro synthesis of uniform poly(dG)-poly(dC) by Klenow exo- fragment of polymerase I. Yes
Klenow fragment Eubacterium A In vitro synthesis of uniform poly(dG)-poly(dC) by Klenow exo- fragment of polymerase I. Yes
Human Pol alpha Eukaryote B Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations. No
Human Pol delta Eukaryote B Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations. Yes
Human Pol epsilon Eukaryote B Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations. Yes
Klenow fragment Eubacterium A The proofreading 3'-->5' exonuclease activity of DNA polymerases: a kinetic barrier to translesion DNA synthesis. Yes
Human Pol gamma Eukaryote A The proofreading 3'-->5' exonuclease activity of DNA polymerases: a kinetic barrier to translesion DNA synthesis. Yes
T4 Virus/Phage B The proofreading 3'-->5' exonuclease activity of DNA polymerases: a kinetic barrier to translesion DNA synthesis. Yes
Klenow fragment Eubacterium A Miscoding potential of the N2-ethyl-2'-deoxyguanosine DNA adduct by the exonuclease-free Klenow fragment of Escherichia coli DNA polymerase I. Yes
Klenow fragment Eubacterium A 3'-5' exonuclease of Klenow fragment: role of amino acid residues within the single-stranded DNA binding region in exonucleolysis and duplex DNA melting. Yes
Phi29 Virus/Phage B Phi29 DNA polymerase residues Tyr59, His61 and Phe69 of the highly conserved ExoII motif are essential for interaction with the terminal protein. Yes
T4 Virus/Phage B Architecture of the bacteriophage T4 replication complex revealed with nanoscale biopointers. Yes
Human Pol alpha Eukaryote B Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III. No
EIAV RT Virus/Phage RT Purification and partial characterization of equine infectious anemia virus reverse transcriptase. No
AMV Virus/Phage RT Purification and partial characterization of equine infectious anemia virus reverse transcriptase. No
HIV RT Virus/Phage RT Purification and partial characterization of equine infectious anemia virus reverse transcriptase. No
Human Pol beta Eukaryote X DNA polymerase family X: function, structure, and cellular roles. No
Human Pol lamba Eukaryote X DNA polymerase family X: function, structure, and cellular roles. No
Human Pol mu Eukaryote X DNA polymerase family X: function, structure, and cellular roles. No
ASFV pol X Virus/Phage X DNA polymerase X of African swine fever virus: insertion fidelity on gapped DNA substrates and AP lyase activity support a role in base excision repair of viral DNA. No
Vent Archaeon B In vitro replication slippage by DNA polymerases from thermophilic organisms. Yes
Tfu Archaeon ? In vitro replication slippage by DNA polymerases from thermophilic organisms. Yes
Pyra exo- Archaeon ? In vitro replication slippage by DNA polymerases from thermophilic organisms. No
Klenow fragment Eubacterium A Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase. Yes
AMV Virus/Phage RT Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase. No
HIV RT Virus/Phage RT Fidelity of DNA synthesis catalyzed by human DNA polymerase alpha and HIV-1 reverse transcriptase: effect of reaction pH. No
AMV Virus/Phage RT Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro. No
MMuLV RT Virus/Phage RT Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro. No
A Virus/Phage B Processive proofreading by the adenovirus DNA polymerase. Association with the priming protein reduces exonucleolytic degradation. Yes
Dpo4 Archaeon Y Low fidelity DNA synthesis by a y family DNA polymerase due to misalignment in the active site. No
Human Pol lamba Eukaryote X The frameshift infidelity of human DNA polymerase lambda. Implications for function. No
Human Pol mu Eukaryote X Highly frequent frameshift DNA synthesis by human DNA polymerase mu. No
Eco Pol III Eubacterium C The base substitution and frameshift fidelity of Escherichia coli DNA polymerase III holoenzyme in vitro. Yes
MutD5 Pol III Eubacterium C The base substitution and frameshift fidelity of Escherichia coli DNA polymerase III holoenzyme in vitro. No
Mouse Pol eta Eukaryote Y Error rate and specificity of human and murine DNA polymerase eta. No
Human Pol eta Eukaryote Y Error rate and specificity of human and murine DNA polymerase eta. No
Human Pol theta Eukaryote A The human DINB1 gene encodes the DNA polymerase Poltheta. No
Sce Pol I Eukaryote B Fidelity of DNA polymerase I and the DNA polymerase I-DNA primase complex from Saccharomyces cerevisiae. No
Human Pol eta Eukaryote Y Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates. No
Human Pol kappa Eukaryote Y Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates. No
Human Pol iota Eukaryote Y Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates. No
Human Pol nu Eukaryote A A unique error signature for human DNA polymerase nu. No
Human Pol nu Eukaryote A Human DNA polymerase N (POLN) is a low fidelity enzyme capable of error-free bypass of 5S-thymine glycol. No
Human Pol epsilon Eukaryote B Characterization of a large form of DNA polymerase delta from HeLa cells that is insensitive to proliferating cell nuclear antigen. Yes
Sce Pol delta Eukaryote B The multiple biological roles of the 3'-->5' exonuclease of Saccharomyces cerevisiae DNA polymerase delta require switching between the polymerase and exonuclease domains. Yes
Mouse pol elta Eukaryote ? Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesis. Yes
Mouse pol elta Eukaryote ? Two forms of DNA polymerase delta from mouse cells. Purification and properties. Yes
Bovine pol elta Eukaryote B Further studies on calf thymus DNA polymerase delta purified to homogeneity by a new procedure. Yes
Bli DNA polymerase Eubacterium A DNA polymerase from mesophilic and thermophilic bacteria. III. Lack of fidelity in the replication of synthetic polydeoxyribonucleotides by DNA polymerase from Bacillus licheniformis and Bacillus stearothermophilus. No
Bst Eubacterium A Thermostable DNA polymerases. No
Tma Pol III Eubacterium C Thermostable DNA polymerases. Yes
Poc Pol I Archaeon B The hyperthermophilic archaeon Pyrodictium occultum has two alpha-like DNA polymerases. Yes
Poc Pol II Archaeon B The hyperthermophilic archaeon Pyrodictium occultum has two alpha-like DNA polymerases. Yes
HIV2 RT Virus/Phage RT Fidelity of the reverse transcriptase of human immunodeficiency virus type 2. No
HIV RT Virus/Phage RT Fidelity of the reverse transcriptase of human immunodeficiency virus type 2. No
Klenow fragment Eubacterium A Fidelity of the reverse transcriptase of human immunodeficiency virus type 2. Yes
Pfu Archaeon B DNA polymerases from hyperthermophiles. Yes
Pfu (exo-) ? ? DNA polymerases from hyperthermophiles. No
Vent Archaeon B DNA polymerases from hyperthermophiles. Yes
PGBD Pol I Archaeon B DNA polymerases from hyperthermophiles. Yes
9egN Archaeon B DNA polymerases from hyperthermophiles. Yes
Taq pol I Eubacterium A DNA polymerases from hyperthermophiles. No
Bst LF Eubacterium A DNA polymerases from hyperthermophiles. No
Klenow fragment Eubacterium A DNA polymerases from hyperthermophiles. Yes
Cal pol gamma Eukaryote A Purification and characterization of a gamma-like DNA polymerase from Chenopodium album L. Yes
Human Pol theta Eukaryote A Low-fidelity DNA synthesis by human DNA polymerase theta. No
Pab Pol I Archaeon B PCR performance of the highly thermostable proof-reading B-type DNA polymerase from Pyrococcus abyssi. Yes
Taq pol I Eubacterium A High fidelity DNA synthesis by the Thermus aquaticus DNA polymerase. No
Human Pol gamma Eukaryote A The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases. Yes
Klenow Fragment D424A Eubacterium A Coordination between the polymerase and 5'-nuclease components of DNA polymerase I of Escherichia coli. No
Eco Pol I D424A Eubacterium A Coordination between the polymerase and 5'-nuclease components of DNA polymerase I of Escherichia coli. No
Eco Pol I - Small Fragment Eubacterium Non Pol Coordination between the polymerase and 5'-nuclease components of DNA polymerase I of Escherichia coli. Unspecified
Eco Pol I Exonuclease I Eubacterium Non Pol THE DEOXYRIBONUCLEASES OF ESCHERICHIA COLI. IV. AN EXONUCLEASE ACTIVITY PRESENT IN PURIFIED PREPARATIONS OF DEOXYRIBONUCLEIC ACID POLYMERASE. Yes
Eco Pol I Exonuclease II Eubacterium Non Pol THE DEOXYRIBONUCLEASES OF ESCHERICHIA COLI. IV. AN EXONUCLEASE ACTIVITY PRESENT IN PURIFIED PREPARATIONS OF DEOXYRIBONUCLEIC ACID POLYMERASE. Yes
Taq pol I Eubacterium A Characterization of the 5' to 3' nuclease activity of Thermus aquaticus DNA polymerase on fluorogenic double-stranded probes. No
Vaccinia Virus Pol Virus/Phage B Enzymatic processing of replication and recombination intermediates by the vaccinia virus DNA polymerase. Yes
Eco Pol I Eubacterium A ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. XIV. FURTHER PURIFICATION AND PROPERTIES OF DEOXYRIBONUCLEIC ACID POLYMERASE OF ESCHERICHIA COLI. Unspecified
Eco Pol I Exonuclease II Eubacterium Non Pol ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. XIV. FURTHER PURIFICATION AND PROPERTIES OF DEOXYRIBONUCLEIC ACID POLYMERASE OF ESCHERICHIA COLI. Yes
T4 Virus/Phage B Enzymatic synthesis of deoxyribonucleic acid. XXV. Purification and properties of deoxyribonucleic acid polymerase induced by infection with phage T4. Yes
Eco Pol I Exonuclease II Eubacterium Non Pol Enzymatic synthesis of deoxyribonucleic acid. XXIX. Hydrolysis of deoxyribonucleic acid from the 5' terminus by an exonuclease function of deoxyribonucleic acid polymerase. Yes
T4 D219A Virus/Phage B Effect of accessory proteins on T4 DNA polymerase replication fidelity. No
T4 Virus/Phage B Effect of accessory proteins on T4 DNA polymerase replication fidelity. Yes
Bsu Eubacterium ? ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. XIV. FURTHER PURIFICATION AND PROPERTIES OF DEOXYRIBONUCLEIC ACID POLYMERASE OF ESCHERICHIA COLI. No
Eco Pol I Eubacterium A Enzymatic synthesis of deoxyribonucleic acid. XXVII. Chemical modifications of deoxyribonucleic acid polymerase. Unspecified
Eco Pol I Eubacterium A Enzymatic synthesis of deoxyribonucleic acid. XXXII. Replication of duplex deoxyribonucleic acid by polymerase at a single strand break. Yes
Eco Pol I Eubacterium A Enzymatic synthesis of deoxyribonucleic acid. XXXV. A 3'-hydroxylribonucleotide binding site of Escherichia coli deoxyribonucleic acid polymerase. Yes
Klenow fragment Eubacterium A Deoxyribonucleic acid polymerase: two distinct enzymes in one polypeptide. II. A proteolytic fragment containing the 5' leads to 3' exonuclease function. Restoration of intact enzyme functions from the two proteolytic fragments. Yes
Eco Pol I - Small Fragment Eubacterium Non Pol Deoxyribonucleic acid polymerase: two distinct enzymes in one polypeptide. II. A proteolytic fragment containing the 5' leads to 3' exonuclease function. Restoration of intact enzyme functions from the two proteolytic fragments. No
Eco Pol I Eubacterium A Deoxyribonucleic acid polymerase: two distinct enzymes in one polypeptide. II. A proteolytic fragment containing the 5' leads to 3' exonuclease function. Restoration of intact enzyme functions from the two proteolytic fragments. Yes
Eco Pol I - Small Fragment Eubacterium Non Pol Deoxyribonucleic acid polymerase: two distinct enzymes in one polypeptide. I. A proteolytic fragment containing the polymerase and 3' leads to 5' exonuclease functions. No
Eco Pol I Eubacterium A Deoxyribonucleic acid polymerase: two distinct enzymes in one polypeptide. I. A proteolytic fragment containing the polymerase and 3' leads to 5' exonuclease functions. Yes
Klenow fragment Eubacterium A Deoxyribonucleic acid polymerase: two distinct enzymes in one polypeptide. I. A proteolytic fragment containing the polymerase and 3' leads to 5' exonuclease functions. Yes
Eco Pol III Holoenzyme Eubacterium C Dynamics of DNA polymerase III holoenzyme of Escherichia coli in replication of a multiprimed template. Yes
Phi29 D12AD66A Virus/Phage B Processive proofreading and the spatial relationship between polymerase and exonuclease active sites of bacteriophage phi29 DNA polymerase. No
T7 Virus/Phage A Processive proofreading and the spatial relationship between polymerase and exonuclease active sites of bacteriophage phi29 DNA polymerase. Yes
Phi29 Virus/Phage B Processive proofreading and the spatial relationship between polymerase and exonuclease active sites of bacteriophage phi29 DNA polymerase. Yes
Phi29 Virus/Phage B Involvement of the "linker" region between the exonuclease and polymerization domains of phi29 DNA polymerase in DNA and TP binding. Yes
SsoDpo1 Archaeon B Strand annealing and terminal transferase activities of a B-family DNA polymerase. Yes
Human Pol gamma D198AG200A Eukaryote A Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers. No
Human Pol gamma Eukaryote A Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers. Yes
Pab pol B Archaeon B Molecular recognition of canonical and deaminated bases by P. abyssi family B DNA polymerase. Yes

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.