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Results for property: 3-5' exo

Detailed Results for Property

Use this page to examine all the the polymerases and references referring to the property: 3-5' exo.

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Polymerase Kingdom Family Reference Result Context
T7 Virus/Phage A T7-induced DNA polymerase. Characterization of associated exonuclease activities and resolution into biologically active subunits. Yes
T7 Virus/Phage A Deoxyribonucleic acid polymerase of bacteriophage T7. Yes
T7 Virus/Phage A Thermostable DNA polymerases. Yes
T7 Virus/Phage A Error-prone replication of repeated DNA sequences by T7 DNA polymerase in the absence of its processivity subunit. Yes
T7 Virus/Phage A Single-molecule studies of the effect of template tension on T7 DNA polymerase activity. Yes
T7 Virus/Phage A The thioredoxin binding domain of bacteriophage T7 DNA polymerase confers processivity on Escherichia coli DNA polymerase I. Yes
T7 Virus/Phage A Fidelity of DNA synthesis by the Thermococcus litoralis DNA polymerase--an extremely heat stable enzyme with proofreading activity. Yes
T7 Virus/Phage A Processive proofreading and the spatial relationship between polymerase and exonuclease active sites of bacteriophage phi29 DNA polymerase. Yes
T7 Virus/Phage A Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant. Yes
T7 Virus/Phage A Deoxyribonucleic acid polymerase of bacteriophage T7. Purification and properties of the phage-encoded subunit, the gene 5 protein. Yes
T7 Virus/Phage A Characterization of bacteriophage T7 DNA polymerase purified to homogeneity by antithioredoxin immunoadsorbent chromatography. Yes
T7 Virus/Phage A T7-induced DNA polymerase. Requirement for thioredoxin sulfhydryl groups. Yes
T7 Virus/Phage A Characterization of strand displacement synthesis catalyzed by bacteriophage T7 DNA polymerase. Yes
9egN Archaeon B Cloning of thermostable DNA polymerases from hyperthermophilic marine Archaea with emphasis on Thermococcus sp. 9 degrees N-7 and mutations affecting 3'-5' exonuclease activity. Yes
9egN Archaeon B DNA polymerases from hyperthermophiles. Yes
TGO Archaeon B Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius. Yes
TGO Archaeon B The 3'-5' proofreading exonuclease of archaeal family-B DNA polymerase hinders the copying of template strand deaminated bases. Yes
KOD1 Archaeon B Catalyzing "hot" reactions: enzymes from hyperthermophilic Archaea. Yes
KOD1 Archaeon B Characterization of DNA polymerase from Pyrococcus sp. strain KOD1 and its application to PCR. Yes
RB69 Virus/Phage B Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family. Yes
Vent Archaeon B Fidelity of Thermococcus litoralis DNA polymerase (Vent) in PCR determined by denaturing gradient gel electrophoresis. Yes
Vent Archaeon B Fidelity of DNA synthesis by the Thermococcus litoralis DNA polymerase--an extremely heat stable enzyme with proofreading activity. Yes
Vent Archaeon B Incorporation of reporter-labeled nucleotides by DNA polymerases. Yes
Vent Archaeon B In vitro replication slippage by DNA polymerases from thermophilic organisms. Yes
Vent Archaeon B DNA polymerases from hyperthermophiles. Yes
Vent Archaeon B Characterization of a DNA polymerase from the hyperthermophile archaea Thermococcus litoralis. Vent DNA polymerase, steady state kinetics, thermal stability, processivity, strand displacement, and exonuclease activities. Yes
T4 D219A Virus/Phage B Probing DNA polymerase-DNA interactions: examining the template strand in exonuclease complexes using 2-aminopurine fluorescence and acrylamide quenching. No
T4 D219A Virus/Phage B Effect of accessory proteins on T4 DNA polymerase replication fidelity. No
T4 Virus/Phage B Enzymatic synthesis of deoxyribonucleic acid. XXV. Purification and properties of deoxyribonucleic acid polymerase induced by infection with phage T4. Yes
T4 Virus/Phage B Effect of accessory proteins on T4 DNA polymerase replication fidelity. Yes
T4 Virus/Phage B A single mutation in bacteriophage T4 DNA polymerase (A737V, tsL141) decreases its processivity as a polymerase and increases its processivity as a 3'-->5' exonuclease. Yes
T4 Virus/Phage B Incorporation of reporter-labeled nucleotides by DNA polymerases. Yes
T4 Virus/Phage B The proofreading 3'-->5' exonuclease activity of DNA polymerases: a kinetic barrier to translesion DNA synthesis. Yes
T4 Virus/Phage B The slow dissociation of the T4 DNA polymerase holoenzyme when stalled by nucleotide omission. An indication of a highly processive enzyme. Unspecified
T4 Virus/Phage B On the role of deoxyribonucleic acid polymerase in determining mutation rates. Characterization of the defect in the T4 deoxyribonucleic acid polymerase caused by the ts L88 mutation. Yes
T4 Virus/Phage B Isolation, characterization, and kinetic properties of truncated forms of T4 DNA polymerase that exhibit 3'-5' exonuclease activity. Yes
T4 Virus/Phage B On the exonuclease activity of phage T4 deoxyribonucleic acid polymerase. Yes
T4 Virus/Phage B Architecture of the bacteriophage T4 replication complex revealed with nanoscale biopointers. Yes
RB69 D222AD327A Virus/Phage B Use of 2-aminopurine fluorescence to study the role of the beta hairpin in the proofreading pathway catalyzed by the phage T4 and RB69 DNA polymerases. No
RB69 beta hairpin- Virus/Phage B Use of 2-aminopurine fluorescence to study the role of the beta hairpin in the proofreading pathway catalyzed by the phage T4 and RB69 DNA polymerases. No
RB69 D222AD327A beta hairpin- Virus/Phage B Use of 2-aminopurine fluorescence to study the role of the beta hairpin in the proofreading pathway catalyzed by the phage T4 and RB69 DNA polymerases. No
T4 W213S Virus/Phage B DNA polymerase proofreading: active site switching catalyzed by the bacteriophage T4 DNA polymerase. No
T4 A737V Virus/Phage B A single mutation in bacteriophage T4 DNA polymerase (A737V, tsL141) decreases its processivity as a polymerase and increases its processivity as a 3'-->5' exonuclease. Yes
T4 L771F Virus/Phage B A single mutation in bacteriophage T4 DNA polymerase (A737V, tsL141) decreases its processivity as a polymerase and increases its processivity as a 3'-->5' exonuclease. Yes
RB69 G258S Virus/Phage B Use of 2-aminopurine fluorescence to study the role of the beta hairpin in the proofreading pathway catalyzed by the phage T4 and RB69 DNA polymerases. No
RB69 G258SD222A/D237A Virus/Phage B Use of 2-aminopurine fluorescence to study the role of the beta hairpin in the proofreading pathway catalyzed by the phage T4 and RB69 DNA polymerases. No
T4 D112AE114A Virus/Phage B DNA polymerase proofreading: active site switching catalyzed by the bacteriophage T4 DNA polymerase. No
Eco Pol I Eubacterium A Characterization of DNA polymerase I*, a form of DNA polymerase I found in Escherichia coli expressing SOS functions. Yes
Eco Pol I Eubacterium A The steady state kinetic parameters and non-processivity of Escherichia coli deoxyribonucleic acid polymerase I. Yes
Eco Pol I Eubacterium A Deoxyribonucleic acid polymerase: two distinct enzymes in one polypeptide. I. A proteolytic fragment containing the polymerase and 3' leads to 5' exonuclease functions. Yes
Eco Pol I Eubacterium A Deoxyribonucleic acid polymerase: two distinct enzymes in one polypeptide. II. A proteolytic fragment containing the 5' leads to 3' exonuclease function. Restoration of intact enzyme functions from the two proteolytic fragments. Yes
Eco Pol I Eubacterium A Enzymatic synthesis of deoxyribonucleic acid. XXXV. A 3'-hydroxylribonucleotide binding site of Escherichia coli deoxyribonucleic acid polymerase. Yes
Eco Pol I Eubacterium A Enzymatic synthesis of deoxyribonucleic acid. XXXII. Replication of duplex deoxyribonucleic acid by polymerase at a single strand break. Yes
Eco Pol I Eubacterium A Enzymatic synthesis of deoxyribonucleic acid. XXVII. Chemical modifications of deoxyribonucleic acid polymerase. Unspecified
Eco Pol I Eubacterium A ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. XIV. FURTHER PURIFICATION AND PROPERTIES OF DEOXYRIBONUCLEIC ACID POLYMERASE OF ESCHERICHIA COLI. Unspecified
Eco Pol I Eubacterium A Thermostable DNA polymerases. Yes
Eco Pol I Eubacterium A Processive DNA synthesis by DNA polymerase II mediated by DNA polymerase III accessory proteins. Yes
Eco Pol I Eubacterium A Incorporation of reporter-labeled nucleotides by DNA polymerases. No
Klenow fragment Eubacterium A Deoxyribonucleic acid polymerase: two distinct enzymes in one polypeptide. I. A proteolytic fragment containing the polymerase and 3' leads to 5' exonuclease functions. Yes
Klenow fragment Eubacterium A The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I. Yes
Klenow fragment Eubacterium A Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. Yes
Klenow fragment Eubacterium A Synthesis of novel poly(dG)-poly(dG)-poly(dC) triplex structure by Klenow exo- fragment of DNA polymerase I. Yes
Klenow fragment Eubacterium A 3'-5' exonuclease of Klenow fragment: role of amino acid residues within the single-stranded DNA binding region in exonucleolysis and duplex DNA melting. Yes
Klenow fragment Eubacterium A In vitro synthesis of uniform poly(dG)-poly(dC) by Klenow exo- fragment of polymerase I. Yes
Klenow fragment Eubacterium A Identification of a new motif required for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I (Klenow fragment): the RRRY motif is necessary for the binding of single-stranded DNA substrate and the template strand of the mismatched duplex. Yes
Klenow fragment Eubacterium A Fidelity of the reverse transcriptase of human immunodeficiency virus type 2. Yes
Klenow fragment Eubacterium A The proofreading 3'-->5' exonuclease activity of DNA polymerases: a kinetic barrier to translesion DNA synthesis. Yes
Klenow fragment Eubacterium A Miscoding potential of the N2-ethyl-2'-deoxyguanosine DNA adduct by the exonuclease-free Klenow fragment of Escherichia coli DNA polymerase I. Yes
Klenow fragment Eubacterium A Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase. Yes
Klenow fragment Eubacterium A DNA polymerases from hyperthermophiles. Yes
Klenow fragment Eubacterium A Contribution of polar residues of the J-helix in the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I (Klenow fragment): Q677 regulates the removal of terminal mismatch. Yes
Klenow fragment Eubacterium A Identification of residues critical for the polymerase activity of the Klenow fragment of DNA polymerase I from Escherichia coli. Yes
Klenow fragment Eubacterium A Deoxyribonucleic acid polymerase: two distinct enzymes in one polypeptide. II. A proteolytic fragment containing the 5' leads to 3' exonuclease function. Restoration of intact enzyme functions from the two proteolytic fragments. Yes
Klenow fragment Eubacterium A The 3'-5' exonuclease of DNA polymerase I of Escherichia coli: contribution of each amino acid at the active site to the reaction. Yes
Dpo4 Archaeon Y Low fidelity DNA synthesis by a y family DNA polymerase due to misalignment in the active site. No
Human Pol eta Eukaryote Y Low fidelity DNA synthesis by human DNA polymerase-eta. No
Human Pol eta Eukaryote Y Pre-Steady-State Kinetic Analysis of Truncated and Full-Length Saccharomyces cerevisiae DNA Polymerase Eta. Yes
Human Pol eta Eukaryote Y Error rate and specificity of human and murine DNA polymerase eta. No
Human Pol eta Eukaryote Y Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates. No
Human Pol eta Eukaryote Y Pre-Steady-State Kinetic Analysis of Truncated and Full-Length Saccharomyces cerevisiae DNA Polymerase Eta. Yes
Human Pol gamma Eukaryote A Characterization of the native and recombinant catalytic subunit of human DNA polymerase gamma: identification of residues critical for exonuclease activity and dideoxynucleotide sensitivity. Yes
Human Pol gamma Eukaryote A Thermostable DNA polymerases. Yes
Human Pol gamma Eukaryote A Characterization of the native and recombinant catalytic subunit of human DNA polymerase gamma: identification of residues critical for exonuclease activity and dideoxynucleotide sensitivity. Yes
Human Pol gamma Eukaryote A The mitochondrial p55 accessory subunit of human DNA polymerase gamma enhances DNA binding, promotes processive DNA synthesis, and confers N-ethylmaleimide resistance. Yes
Human Pol gamma Eukaryote A The proofreading 3'-->5' exonuclease activity of DNA polymerases: a kinetic barrier to translesion DNA synthesis. Yes
Human Pol gamma Eukaryote A A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase. Yes
Human Pol gamma Eukaryote A Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers. Yes
Human Pol gamma Eukaryote A Expression, purification, and initial kinetic characterization of the large subunit of the human mitochondrial DNA polymerase. Yes
Human Pol gamma Eukaryote A Exonucleolytic proofreading by a mammalian DNA polymerase. Yes
Human Pol gamma Eukaryote A The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases. Yes
Eco Pol IV Eubacterium Y The beta clamp targets DNA polymerase IV to DNA and strongly increases its processivity. No
Eco Pol IV Eubacterium Y The dinB gene encodes a novel E. coli DNA polymerase, DNA pol IV, involved in mutagenesis. No
Human Pol kappa Eukaryote Y Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates. No
Human Pol kappa Eukaryote Y Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene. No
Human Pol kappa Eukaryote Y Purification and characterization of pol kappa, a DNA polymerase encoded by the human DINB1 gene. No
Human Pol beta Eukaryote X DNA polymerase family X: function, structure, and cellular roles. No
Human Pol beta Eukaryote X Thermostable DNA polymerases. No
Human Pol beta Eukaryote X Expression of human DNA polymerase beta in Escherichia coli and characterization of the recombinant enzyme. No
Human Pol beta Eukaryote X Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism. No
Rat Pol beta Eukaryote X Autonomous 3'-->5' exonucleases can proofread for DNA polymerase beta from rat liver. Yes
T5 Virus/Phage A Exonuclease associated with bacteriophage T5-Induced DNA polymerase. Yes
Streptococcus pneumoniae Pol I Eubacterium A Streptococcus pneumoniae DNA polymerase I lacks 3'-to-5' exonuclease activity: localization of the 5'-to-3' exonucleolytic domain. No
Streptococcus pneumoniae Pol I Eubacterium A The 5' to 3' exonuclease activity of DNA polymerase I is essential for Streptococcus pneumoniae. No
Streptococcus pneumoniae Pol I Eubacterium A Characterization of the polA gene of Streptococcus pneumoniae and comparison of the DNA polymerase I it encodes to homologous enzymes from Escherichia coli and phage T7. Yes
Taq pol I Eubacterium A Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. No
Taq pol I Eubacterium A Thermostable DNA polymerases. No
Taq pol I Eubacterium A Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase. No
Taq pol I Eubacterium A Characterization of the 5' to 3' nuclease activity of Thermus aquaticus DNA polymerase on fluorogenic double-stranded probes. No
Taq pol I Eubacterium A Fidelity of Thermococcus litoralis DNA polymerase (Vent) in PCR determined by denaturing gradient gel electrophoresis. No
Taq pol I Eubacterium A High fidelity DNA synthesis by the Thermus aquaticus DNA polymerase. No
Taq pol I Eubacterium A DNA polymerases from hyperthermophiles. No
Taq pol I Eubacterium A Incorporation of reporter-labeled nucleotides by DNA polymerases. No
Tth Pol I Eubacterium A Reverse transcription and DNA amplification by a Thermus thermophilus DNA polymerase. No
Tma Pol III Eubacterium C Thermostable DNA polymerases. Yes
Tne pol Eubacterium A Domain exchange: chimeras of Thermus aquaticus DNA polymerase, Escherichia coli DNA polymerase I and Thermotoga neapolitana DNA polymerase. Yes
HIV RT Virus/Phage RT Purification and partial characterization of equine infectious anemia virus reverse transcriptase. No
HIV RT Virus/Phage RT Fidelity of the reverse transcriptase of human immunodeficiency virus type 2. No
HIV RT Virus/Phage RT Human immunodeficiency virus 1 reverse transcriptase. Template binding, processivity, strand displacement synthesis, and template switching. No
HIV RT Virus/Phage RT Fidelity of DNA synthesis catalyzed by human DNA polymerase alpha and HIV-1 reverse transcriptase: effect of reaction pH. No
Pfu Archaeon B High-fidelity amplification using a thermostable DNA polymerase isolated from Pyrococcus furiosus. Yes
Pfu Archaeon B DNA polymerases from hyperthermophiles. Yes
Pfu Archaeon B The 3'-5' proofreading exonuclease of archaeal family-B DNA polymerase hinders the copying of template strand deaminated bases. Yes
Pfu Archaeon B Incorporation of reporter-labeled nucleotides by DNA polymerases. Yes
Eco Pol III Eubacterium C Fidelity of Escherichia coli DNA polymerase III holoenzyme. The effects of beta, gamma complex processivity proteins and epsilon proofreading exonuclease on nucleotide misincorporation efficiencies. Yes
Eco Pol III Eubacterium C Thermostable DNA polymerases. Yes
Eco Pol III Eubacterium C Processive DNA synthesis by DNA polymerase II mediated by DNA polymerase III accessory proteins. Yes
Eco Pol III Eubacterium C The base substitution and frameshift fidelity of Escherichia coli DNA polymerase III holoenzyme in vitro. Yes
Tth Pol III Eubacterium C DNA polymerase III holoenzyme from Thermus thermophilus identification, expression, purification of components, and use to reconstitute a processive replicase. Yes
Human Pol lamba Eukaryote X DNA polymerase lambda, a novel DNA repair enzyme in human cells. No
Human Pol lamba Eukaryote X The frameshift infidelity of human DNA polymerase lambda. Implications for function. No
Human Pol lamba Eukaryote X DNA polymerase family X: function, structure, and cellular roles. No
Human Pol mu Eukaryote X DNA polymerase mu (Pol mu), homologous to TdT, could act as a DNA mutator in eukaryotic cells. No
Human Pol mu Eukaryote X Highly frequent frameshift DNA synthesis by human DNA polymerase mu. No
Human Pol mu Eukaryote X DNA polymerase family X: function, structure, and cellular roles. No
Human Pol iota Eukaryote Y Preferential incorporation of G opposite template T by the low-fidelity human DNA polymerase iota. No
Human Pol iota Eukaryote Y Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates. No
Phi29 Virus/Phage B Involvement of the "linker" region between the exonuclease and polymerization domains of phi29 DNA polymerase in DNA and TP binding. Yes
Phi29 Virus/Phage B Functional characterization of highly processive protein-primed DNA polymerases from phages Nf and GA-1, endowed with a potent strand displacement capacity. Yes
Phi29 Virus/Phage B A specific subdomain in phi29 DNA polymerase confers both processivity and strand-displacement capacity. Yes
Phi29 Virus/Phage B TempliPhi, phi29 DNA polymerase based rolling circle amplification of templates for DNA sequencing. Yes
Phi29 Virus/Phage B Functional importance of bacteriophage phi29 DNA polymerase residue Tyr148 in primer-terminus stabilisation at the 3'-5' exonuclease active site. Yes
Phi29 Virus/Phage B Phi29 DNA polymerase residues Tyr59, His61 and Phe69 of the highly conserved ExoII motif are essential for interaction with the terminal protein. Yes
Phi29 Virus/Phage B Processive proofreading and the spatial relationship between polymerase and exonuclease active sites of bacteriophage phi29 DNA polymerase. Yes
Phi29 Virus/Phage B The bacteriophage phi 29 DNA polymerase, a proofreading enzyme. Yes
PGBD Pol I Archaeon B Fidelity and predominant mutations produced by deep vent wild-type and exonuclease-deficient DNA polymerases during in vitro DNA amplification. Yes
PGBD Pol I Archaeon B Incorporation of reporter-labeled nucleotides by DNA polymerases. Yes
PGBD Pol I Archaeon B DNA polymerases from hyperthermophiles. Yes
Bst Eubacterium A Thermostable DNA polymerases. No
Bst Eubacterium A Thermostable Bst DNA polymerase I lacks a 3'-->5' proofreading exonuclease activity. No
Bsu (large fragment) Eubacterium ? ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. XV. PURIFICATION AND PROPERTIES OF A POLYMERASE FROM BACILLUS SUBTILIS. No
MMuLV RT Virus/Phage RT Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro. No
Bst LF Eubacterium A DNA polymerases from hyperthermophiles. No
Bst LF Eubacterium A Thermostable Bst DNA polymerase I lacks a 3'-->5' proofreading exonuclease activity. No
Bst LF Eubacterium A Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. No
Bsu Eubacterium ? ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. XIV. FURTHER PURIFICATION AND PROPERTIES OF DEOXYRIBONUCLEIC ACID POLYMERASE OF ESCHERICHIA COLI. No
Bsu Eubacterium ? DNA polymerase III gene of Bacillus subtilis. Yes
Klenow (exo-) Eubacterium A Kinetics of DNA polymerase I (Klenow fragment exo-) activity on damaged DNA templates: effect of proximal and distal template damage on DNA synthesis. No
Klenow (exo-) Eubacterium A In vitro synthesis of uniform poly(dG)-poly(dC) by Klenow exo- fragment of polymerase I. Yes
Klenow (exo-) Eubacterium A Synthesis of novel poly(dG)-poly(dG)-poly(dC) triplex structure by Klenow exo- fragment of DNA polymerase I. No
Klenow (exo-) Eubacterium A Effect of reaction pH on the fidelity and processivity of exonuclease-deficient Klenow polymerase. No
Vent (exo-) Archaeon B Fidelity of DNA synthesis by the Thermococcus litoralis DNA polymerase--an extremely heat stable enzyme with proofreading activity. No
Deep Vent (exo-) Archaeon B Unnatural imidazopyridopyrimidine:naphthyridine base pairs: selective incorporation and extension reaction by Deep Vent (exo- ) DNA polymerase. No
Replinase Unknown ? Fidelity of DNA synthesis by the Thermococcus litoralis DNA polymerase--an extremely heat stable enzyme with proofreading activity. No
Sequenase Virus/Phage A Fidelity of Thermococcus litoralis DNA polymerase (Vent) in PCR determined by denaturing gradient gel electrophoresis. No
AMV Virus/Phage RT Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro. No
AMV Virus/Phage RT On the fidelity of DNA replication. Lack of exodeoxyribonuclease activity and error-correcting function in avian myeloblastosis virus DNA polymerase. No
AMV Virus/Phage RT Purification and partial characterization of equine infectious anemia virus reverse transcriptase. No
AMV Virus/Phage RT Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase. No
T2 Virus/Phage B Separation of deoxyribo-oligonucleotidases induced by infection with bacteriophage T2. No
Terminal Transferase Unknown ? Characterization of the homopolymer tailing reaction catalyzed by terminal deoxynucleotidyl transferase. Implications for the cloning of cDNA. No
phi29 T434N Virus/Phage B Primer-terminus stabilization at the psi 29 DNA polymerase active site. Mutational analysis of conserved motif TX2GR. Yes
phi29 R438I Virus/Phage B Primer-terminus stabilization at the psi 29 DNA polymerase active site. Mutational analysis of conserved motif TX2GR. Yes
phi29 A437G Virus/Phage B Primer-terminus stabilization at the psi 29 DNA polymerase active site. Mutational analysis of conserved motif TX2GR. Yes
phi29 R438K Virus/Phage B Primer-terminus stabilization at the psi 29 DNA polymerase active site. Mutational analysis of conserved motif TX2GR. Yes
Bli DNA polymerase Eubacterium A DNA polymerase from mesophilic and thermophilic bacteria. III. Lack of fidelity in the replication of synthetic polydeoxyribonucleotides by DNA polymerase from Bacillus licheniformis and Bacillus stearothermophilus. No
Thermo JDF-3 pol Archaeon B Efficient and high fidelity incorporation of dye-terminators by a novel archaeal DNA polymerase mutant. Yes
Human Pol alpha Eukaryote B Thermostable DNA polymerases. No
Human Pol alpha Eukaryote B Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations. No
Human Pol alpha Eukaryote B Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. No
Human Pol alpha Eukaryote B Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerases. No
Human Pol alpha Eukaryote B Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III. No
T7 (purified without EDTA) Virus/Phage A Characterization of strand displacement synthesis catalyzed by bacteriophage T7 DNA polymerase. Yes
T7 (purified without EDTA) Virus/Phage A Two forms of the DNA polymerase of bacteriophage T7. Yes
Eco Pol II Eubacterium B Thermostable DNA polymerases. Yes
Eco Pol II Eubacterium B Processive DNA synthesis by DNA polymerase II mediated by DNA polymerase III accessory proteins. Yes
Eco Pol II Eubacterium B Purification and DNA synthesis in cell-free extracts: properties of DNA polymerase II. Unspecified
Eco Pol II Eubacterium B Proofreading-defective DNA polymerase II increases adaptive mutation in Escherichia coli. Yes
Eco Pol II exo- Eubacterium B Proofreading-defective DNA polymerase II increases adaptive mutation in Escherichia coli. No
EBV Pol Virus/Phage B Characterization of 3'-to 5'-exonuclease activity associated with Epstein-Barr virus DNA polymerase. Yes
Human Pol delta Eukaryote B The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability. Yes
Human Pol delta Eukaryote B Thermostable DNA polymerases. Yes
Human Pol delta Eukaryote B Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. Yes
Human Pol delta Eukaryote B Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations. Yes
KF D424A Eubacterium A The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I. No
KF D424A Eubacterium A The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I. No
KF D355AE357A Eubacterium A The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I. No
KF(515-928) Eubacterium A The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I. No
Human Pol epsilon Eukaryote B Thermostable DNA polymerases. Yes
Human Pol epsilon Eukaryote B Characterization of a large form of DNA polymerase delta from HeLa cells that is insensitive to proliferating cell nuclear antigen. Yes
Human Pol epsilon Eukaryote B Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations. Yes
Human Pol epsilon Eukaryote B Evolution of DNA polymerases: an inactivated polymerase-exonuclease module in Pol epsilon and a chimeric origin of eukaryotic polymerases from two classes of archaeal ancestors. Yes
Human Pol epsilon Eukaryote B Subunit protein-affinity isolation of Drosophila DNA polymerase catalytic subunit. Yes
Human Pol epsilon Eukaryote B Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. Yes
DTok Archaeon B Crystal structure of an archaebacterial DNA polymerase. Yes
Sce Pol alpha Eukaryote B Purification and characterization of the 180- and 86-kilodalton subunits of the Saccharomyces cerevisiae DNA primase-DNA polymerase protein complex. The 180-kilodalton subunit has both DNA polymerase and 3'----5'-exonuclease activities. Yes
Sce Pol alpha Eukaryote B Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme. No
HHV1 Virus/Phage B Finger domain mutation affects enzyme activity, DNA replication efficiency, and fidelity of an exonuclease-deficient DNA polymerase of herpes simplex virus type 1. Yes
Sce Pol delta Eukaryote B The multiple biological roles of the 3'-->5' exonuclease of Saccharomyces cerevisiae DNA polymerase delta require switching between the polymerase and exonuclease domains. Yes
Sce Pol delta Eukaryote B The 3' to 5' exonuclease activity located in the DNA polymerase delta subunit of Saccharomyces cerevisiae is required for accurate replication. Yes
phi29 D332Y ? ? An aspartic acid residue in TPR-1, a specific region of protein-priming DNA polymerases, is required for the functional interaction with primer terminal protein. Yes
HIV2 RT Virus/Phage RT Fidelity of the reverse transcriptase of human immunodeficiency virus type 2. No
Bsu Pol X Eubacterium X Characterization of a Bacillus subtilis 64-kDa DNA polymerase X potentially involved in DNA repair. Yes
Bsu Pol X Eubacterium X Editing of misaligned 3'-termini by an intrinsic 3'-5' exonuclease activity residing in the PHP domain of a family X DNA polymerase. Yes
Human Pol theta Eukaryote A The human DINB1 gene encodes the DNA polymerase Poltheta. No
Human Pol theta Eukaryote A Low-fidelity DNA synthesis by human DNA polymerase theta. No
Pol eta Y52E Eukaryote Y Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. No
Pol eta Y52F Eukaryote Y Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. No
Pol eta Y52A Eukaryote Y Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. No
HHV1 YD12 Virus/Phage ? Finger domain mutation affects enzyme activity, DNA replication efficiency, and fidelity of an exonuclease-deficient DNA polymerase of herpes simplex virus type 1. No
HHV1 L774F Virus/Phage ? Finger domain mutation affects enzyme activity, DNA replication efficiency, and fidelity of an exonuclease-deficient DNA polymerase of herpes simplex virus type 1. No
Tae pol A Eukaryote B Mammalian proliferating cell nuclear antigen stimulates the processivity of two wheat embryo DNA polymerases. No
Tae pol B Eukaryote ? Mammalian proliferating cell nuclear antigen stimulates the processivity of two wheat embryo DNA polymerases. Yes
Tae pol CI Eukaryote ? Mammalian proliferating cell nuclear antigen stimulates the processivity of two wheat embryo DNA polymerases. No
Tae pol CII Eubacterium ? Mammalian proliferating cell nuclear antigen stimulates the processivity of two wheat embryo DNA polymerases. No
Tgu Archaeon B Characterization and PCR optimization of the thermostable family B DNA polymerase from Thermococcus guaymasensis Yes
T7 (exo-) Virus/Phage A Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant. No
Vaccinia Virus Pol Virus/Phage B Enzymatic processing of replication and recombination intermediates by the vaccinia virus DNA polymerase. Yes
Vaccinia Virus Pol Virus/Phage B Characterization of a processive form of the vaccinia virus DNA polymerase. Yes
Dme Pol delta Eukaryote B Drosophila DNA polymerase delta. Purification and characterization. Yes
ASFV pol X Virus/Phage X Characterization of an African swine fever virus 20-kDa DNA polymerase involved in DNA repair. No
ASFV pol X Virus/Phage X DNA polymerase X of African swine fever virus: insertion fidelity on gapped DNA substrates and AP lyase activity support a role in base excision repair of viral DNA. No
Eco Pol I* Eubacterium A Characterization of DNA polymerase I*, a form of DNA polymerase I found in Escherichia coli expressing SOS functions. Yes
SsoDpo1 Archaeon B Strand annealing and terminal transferase activities of a B-family DNA polymerase. Yes
Pol Kappa (exo-) Eukaryote Y Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene. No
Sce Pol III Eukaryote C Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme. Yes
Sce Pol II Eukaryote B Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme. Yes
A Virus/Phage B Properties of the adenovirus DNA polymerase. Yes
A Virus/Phage B Processive proofreading by the adenovirus DNA polymerase. Association with the priming protein reduces exonucleolytic degradation. Yes
Nf Virus/Phage B Functional characterization of highly processive protein-primed DNA polymerases from phages Nf and GA-1, endowed with a potent strand displacement capacity. Yes
GA-1 Virus/Phage B Functional characterization of highly processive protein-primed DNA polymerases from phages Nf and GA-1, endowed with a potent strand displacement capacity. Yes
phi29 (-TPR2) Virus/Phage B A specific subdomain in phi29 DNA polymerase confers both processivity and strand-displacement capacity. Yes
Sce Pol II* Eukaryote ? Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme. Yes
Pab Pol I Archaeon B PCR performance of the highly thermostable proof-reading B-type DNA polymerase from Pyrococcus abyssi. Yes
EIAV RT Virus/Phage RT Purification and partial characterization of equine infectious anemia virus reverse transcriptase. No
Pyra exo- Archaeon ? In vitro replication slippage by DNA polymerases from thermophilic organisms. No
Tfu Archaeon ? In vitro replication slippage by DNA polymerases from thermophilic organisms. Yes
MutD5 Pol III Eubacterium C The base substitution and frameshift fidelity of Escherichia coli DNA polymerase III holoenzyme in vitro. No
Mouse Pol eta Eukaryote Y Error rate and specificity of human and murine DNA polymerase eta. No
Sce Pol I Eukaryote B Fidelity of DNA polymerase I and the DNA polymerase I-DNA primase complex from Saccharomyces cerevisiae. No
Human Pol nu Eukaryote A Human DNA polymerase N (POLN) is a low fidelity enzyme capable of error-free bypass of 5S-thymine glycol. No
Human Pol nu Eukaryote A A unique error signature for human DNA polymerase nu. No
Bovine pol elta Eukaryote B Further studies on calf thymus DNA polymerase delta purified to homogeneity by a new procedure. Yes
Mouse pol elta Eukaryote ? Two forms of DNA polymerase delta from mouse cells. Purification and properties. Yes
Mouse pol elta Eukaryote ? Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesis. Yes
Poc Pol I Archaeon B The hyperthermophilic archaeon Pyrodictium occultum has two alpha-like DNA polymerases. Yes
Poc Pol II Archaeon B The hyperthermophilic archaeon Pyrodictium occultum has two alpha-like DNA polymerases. Yes
Pfu (exo-) ? ? DNA polymerases from hyperthermophiles. No
Cal pol gamma Eukaryote A Purification and characterization of a gamma-like DNA polymerase from Chenopodium album L. Yes
Eco Pol I D424A Eubacterium A Coordination between the polymerase and 5'-nuclease components of DNA polymerase I of Escherichia coli. No
Eco Pol I - Small Fragment Eubacterium Non Pol Coordination between the polymerase and 5'-nuclease components of DNA polymerase I of Escherichia coli. Unspecified
Eco Pol I - Small Fragment Eubacterium Non Pol Deoxyribonucleic acid polymerase: two distinct enzymes in one polypeptide. II. A proteolytic fragment containing the 5' leads to 3' exonuclease function. Restoration of intact enzyme functions from the two proteolytic fragments. No
Eco Pol I - Small Fragment Eubacterium Non Pol Deoxyribonucleic acid polymerase: two distinct enzymes in one polypeptide. I. A proteolytic fragment containing the polymerase and 3' leads to 5' exonuclease functions. No
Klenow Fragment D424A Eubacterium A Coordination between the polymerase and 5'-nuclease components of DNA polymerase I of Escherichia coli. No
Eco Pol I Exonuclease I Eubacterium Non Pol THE DEOXYRIBONUCLEASES OF ESCHERICHIA COLI. IV. AN EXONUCLEASE ACTIVITY PRESENT IN PURIFIED PREPARATIONS OF DEOXYRIBONUCLEIC ACID POLYMERASE. Yes
Eco Pol I Exonuclease II Eubacterium Non Pol ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. XIV. FURTHER PURIFICATION AND PROPERTIES OF DEOXYRIBONUCLEIC ACID POLYMERASE OF ESCHERICHIA COLI. Yes
Eco Pol I Exonuclease II Eubacterium Non Pol Enzymatic synthesis of deoxyribonucleic acid. XXIX. Hydrolysis of deoxyribonucleic acid from the 5' terminus by an exonuclease function of deoxyribonucleic acid polymerase. Yes
Eco Pol I Exonuclease II Eubacterium Non Pol THE DEOXYRIBONUCLEASES OF ESCHERICHIA COLI. IV. AN EXONUCLEASE ACTIVITY PRESENT IN PURIFIED PREPARATIONS OF DEOXYRIBONUCLEIC ACID POLYMERASE. Yes
Eco Pol III Holoenzyme Eubacterium C Dynamics of DNA polymerase III holoenzyme of Escherichia coli in replication of a multiprimed template. Yes
Phi29 D12AD66A Virus/Phage B Processive proofreading and the spatial relationship between polymerase and exonuclease active sites of bacteriophage phi29 DNA polymerase. No
Pab pol B Archaeon B Molecular recognition of canonical and deaminated bases by P. abyssi family B DNA polymerase. Yes
Human Pol gamma D198AG200A Eukaryote A Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers. No

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