show help

References

Welcome to the reference index page

This page displays summary information about all the references in Polbase. Select one of the reference titles to see more information about it.

Choose the "with structures only" box to limit this list to only those references that report an experimentally determined structure.

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.


Title Authors Journal Year Status Validated by
Role of genetic diversity amongst HIV-1 non-B subtypes in drug resistance: a systematic review of virologic and biochemical evidence. Jorge L Martínez-Cajas, Nitika Pant-Pai, Marina B Klein, Mark A. Wainberg AIDS reviews pols set
? new
? new
Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. G T Tan, J M Pezzuto, A D Kinghorn, Stephen H Hughes Journal of natural products pols set
? new
? new
? new
Evolution and degeneration of eukaryotic DNA replication system. Masaharu Takemura Bio Systems new
? new
? new
Structure-based pharmacophore identification of new chemical scaffolds as non-nucleoside reverse transcriptase inhibitors. Maria Letizia Barreca, Laura De Luca, Nunzio Iraci, Angela Rao, Stefania Ferro, Giovanni Maga, Alba Chimirri Journal of chemical information and modeling pols set
? new
? new
Telomerase activity in thyroid neoplasms evaluated by the expression of human telomerase reverse transcriptase (hTERT). Yasuhiro Ito, Hiroshi Yoshida, Chisato Tomoda, Takashi Uruno, Yuuki Takamura, Akihiro Miya, Kaoru Kobayashi, Fumio Matsuzuka, Kanji Kuma, Akira Miyauchi Anticancer research new
? new
? new
Urinary tract infection drives genome instability in uropathogenic Escherichia coli and necessitates translesion synthesis DNA polymerase IV for virulence. Damian Gawel, Patrick C Seed Virulence topics set
? new
[Antiviral strategies in the replication of human immunodeficiency virus]. Mark A. Wainberg, S Bour, R Geleziunas, Z Bentwich L'unión médicale du Canada pols set
? new
Antonia A Nemec ? new
? new
? new
? new
? new
? new
Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues. Y Kuchino, F Mori, Hironori Kasai, H Inoue, Shigenori Iwai, K Miura, E Ohtsuka, Susumu Nishimura Nature pols set
[RNA-dependent DNA-polymerase from avian myeloblastosis virus: effectiveness of interaction with oligothymidylate primers of various length]. I A Lokhova, G A Nevinskiĭ, N A Bulychev, V V Gorn, A S Levina, N K Rudenko, V M Kavsan, Olga I Lavrik Molekuliarnaia biologiia new
? new
? new
? new
? new
Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination. Sherine S L Chan, Janine H Santos, Joel N Meyer, Bhaskar S Mandavilli, Dennis L Cook, Consuelo L McCash, Grace E Kissling, Abraham Nyska, Julie F Foley, Bennett Van Houten, William C Copeland, Vernon E Walker, Kristine L Witt, Jack B Bishop Environmental and molecular mutagenesis pols set
? pols set
? new
? new
Perspectives of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection. Erik De Clercq Farmaco (Società chimica italiana : 1989) pols set
Zhonghua yi xue za zhi new
? new
? new
On the detection of multiple-binding modes of ligands to proteins, from biological, structural, and modeling data. Paul J Lewi, Marc R De Jonge, Frits F D Daeyaert, Luc Koymans, Maarten H Vinkers, Jan Heeres, Paul A J Janssen, Edward Arnold, Kalyan Das, Art D Clark, Stephen H Hughes, Paul L Boyer, Marie-Pierre P De Béthune, Rudi Pauwels, Koen Andries, Michael Kukla, Donald W Ludovici, Bart De Corte, Robert W Kavash, Chih Y Ho, Paul J Lewis Journal of computer-aided molecular design pols set
Novel compounds in preclinical/early clinical development for the treatment of HIV infections. Erik De Clercq Reviews in medical virology pols set
Journal of virological methods topics set
[Preparation of photoreactive oligonucleotide duplexes and their application for photoaffinity modification of DNA-binding proteins]. D Iu Khlimankov, Irina O Petruseva, Nadejda I Rechkunova, Ekaterina A Belousova, Dmitry M Kolpashchikov, Svetlana N Khodyreva, Olga I Lavrik Bioorganicheskaia khimiia new
? new
? new
N-3 substituted TSAO derivatives as a probe to explore the dimeric interface of HIV-1 reverse transcriptase. María-Cruz Bonache, Cristina Chamorro, Sonsoles Velázquez, Erik De Clercq, Jan Balzarini, María-José Camarasa, Ana San-Félix Nucleosides, nucleotides & nucleic acids pols set
? new
[Isolation and characteristics of endonuclease tightly bound to alpha-polymerase from the rat liver]. N A Timchenko, I V Shevelev, S N Drobchenko, O P Zhuchenko, V M Krutiakov Molekuliarnaia biologiia new
New developments in anti-HIV chemotherapy. Erik De Clercq Farmaco (Società chimica italiana : 1989) pols set
Antiviral activity and resistance profile of phosphazid--a novel prodrug of AZT. J Machado, H Salomon, Maureen Oliveira, C Tsoukas, A A Krayevsky, Mark A. Wainberg Nucleosides & nucleotides new
Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: clinical and molecular genetic study. Petri Luoma, Atle Melberg, Juha O Rinne, Jyrki A Kaukonen, Nina N Nupponen, Richard M Chalmers, Anders Oldfors, Ilkka Rautakorpi, Leena Peltonen, Kari Majamaa, Hannu Somer, Anu Suomalainen Lancet pols set
? new
Jianhong Wu ? new
? new
A review of recent experiments on step-to-step "hand-off" of the DNA intermediates in mammalian base excision repair pathways. Rajendra Prasad, William A Beard, Vinod K Batra, Yuan Liu, David D Shock, Samuel H Wilson Molekuliarnaia biologiia new
? new
? new
? new
Jianhong Wu ? new
Human DNA Polymerase-beta Promoter: Phorbol Ester Activation Is Mediated through the cAMP Response Element and cAMP-Response-Element-Binding Protein. X.-P. Yang, Feng He, Teresa Y Rawson, Samuel H Wilson Journal of biomedical science pols set
? new
Localization of the large subunit of replication factor C near the 5' end of DNA primers. Dmitry M Kolpashchikov, Patrick Hughes, Alain Favre, Giuseppe Baldacci, Olga I Lavrik Journal of molecular recognition : JMR new
[Flap endonuclease-1 and its role in the processes of DNA metabolism in eucaryotic cells]. Zh K Nazarkina, Olga I Lavrik, Svetlana N Khodyreva Molekuliarnaia biologiia new
DNA synthesis enzymes and proliferating cell nuclear antigen in normal and neoplastic nerve cells. A Verri, S Verzeletti, P Mazzarello, Silvio Spadari, M Negri, G Bunone, G Della Valle, Ulrich Hübscher, Federico Focher Anticancer research new
? new
? new
? topics set
? new
? new
HIV-reverse transcriptase and human DNA polymerase alpha share amino acid sequence homologies to bacterial penicillin-binding proteins. P Hafkemeyer, K A Neftel, Ulrich Hübscher Methods and findings in experimental and clinical pharmacology pols set
? new
A new highly efficient photoreactive analogue of dCTP. Synthesis, characterization, and application in photoaffinity modification of DNA binding proteins. Sergey V Dezhurov, Svetlana N Khodyreva, Ekaterina S Plekhanova, Olga I Lavrik Bioconjugate chemistry new
? new
Synthesis of base-substituted dUTP analogues carrying a photoreactive group and their application to study human replication protein A. Dmitry M Kolpashchikov, T M Ivanova, V S Boghachev, Heinz Peter Nasheuer, Klaus Weisshart, Alain Favre, P E Pestryakov, Olga I Lavrik Bioconjugate chemistry new
? new
? new
? new
? new
? new
? new
Mutagenesis dependent upon the combination of activation-induced deaminase expression and a double-strand break. Vladimir P Poltoratsky, Michelle L Heacock, Grace E Kissling, Rajendra Prasad, Samuel H Wilson Molecular immunology new
Revista do Instituto de Medicina Tropical de Sao Paulo topics set
[Interaction of replication protein A and flap endonuclease 1 with DNA duplexes containing a nick or flap]. D Iu Khlimankov, Nadejda I Rechkunova, Svetlana N Khodyreva, Irina O Petruseva, Zh K Nazarkina, Ekaterina A Belousova, Olga I Lavrik Molekuliarnaia biologiia new
[Interaction of human replication protein A with DNA-duplexes, containing gaps of varying sizes]. D Iu Khlimankov, Nadejda I Rechkunova, Dmitry M Kolpashchikov, Irina O Petruseva, Svetlana N Khodyreva, A Favr, Olga I Lavrik Molekuliarnaia biologiia new
[Polymorphism of 5' promotor region of mitochondrial gamma-DNA-polymerase gene in human populations]. B A Maliarchuk, M A Perkova, Miroslava V Derenko Molekuliarnaia biologiia new
? new
? new
? new
? new
? new
? new
? new
? new
? new
? new
? new
? new
? new
DNA repair topics set
? new
The role of Tat in HIV-1 replication: an activator and/or a suppressor? Chen Liang, Mark A. Wainberg AIDS reviews pols set
[DNA polymerases beta and lambda, and their roles in the DNA replication and repair]. Ekaterina A Belousova, Olga I Lavrik Molekuliarnaia biologiia new
Cloning and expression of gene 2, required for the protein-primed initiation of the Bacillus subtilis phage phi 29 DNA replication. Luis Blanco, J A García, Margarita Salas Gene new
? new
? new
? new
? new
? new
In vitro study of resistance-associated genotypic mutations to nucleoside analogs. N Gashnikova, O Plyasunova, Y Kiseleva, N Fedyuk, A Pokrovsky Nucleosides, nucleotides & nucleic acids pols set
? new
The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability. S Sharma, CM Helchowski, CE Canman Mutation research topics set
? new
Cotransfection of mutated forms of human immunodeficiency virus type 1 Gag-Pol with wild-type constructs can interfere with processing and viral replication. N Morin, E Cherry, Xincang Li, Mark A. Wainberg Journal of human virology new
? new
Enhanced inhibition of HIV-1 replication in macrophages by antisense oligonucleotides, ribozymes and acyclic nucleoside phosphonate analogs delivered in pH-sensitive liposomes. N Düzgünes, S Simões, V Slepushkin, E Pretzer, J J Rossi, Erik De Clercq, V P Antao, M L Collins, M C de Lima Nucleosides, nucleotides & nucleic acids pols set
? new
? new
? new
? new
? new
? new
? new
Application of the C4'-alkylated deoxyribose primer system (CAPS) in allele-specific real-time PCR for increased selectivity in discrimination of single nucleotide sequence variants. Björn Tews, Jochen Wilhelm, Daniel Summerer, Michael Strerath, Andreas Marx, Peter Friedhoff, Alfred Pingoud, Meinhard Hahn Biological chemistry new
? new
? new
[Quantitative parameters of the 3'-5'-exonuclease reaction of human apurinic/apyrimidinic endonuclease 1 and DNA with single-strand breaks containing dYMP or their modified analogues]. Nadezhda S Dyrkheeva, Svetlana N Khodyreva, Olga I Lavrik Bioorganicheskaia khimiia new
Changes in DNA polymerases alpha, beta and gamma in mouse liver as a function of age. Fumio Hanaoka, J Sayato, H Arai, N Hasegawa, N Inui, Y Mitsui, Masami Yamada Mechanisms of ageing and development new
? new
Structural determinants of HIV-1 reverse transcriptase stereoselectivity towards (beta)-L-deoxy- and dideoxy-pyrimidine nucleoside triphosphates: molecular basis for the combination of L-dideoxynucleoside analogs with non-nucleoside inhibitors in anti HIV chemotherapy. Giovanni Maga, Mario Amacker, Ulrich Hübscher, G Gosselin, J L Imbach, C Mathé, A Faraj, J P Sommadossi, Silvio Spadari Nucleosides & nucleotides pols set
[3'-->5'-exonucleases of the rat liver and the correction of replication errors]. N V Beliakova, N E Kleĭner, T P Kravetskaia, O K Legina, S N Naryzhnyĭ, F V Perrino, I V Shevelev, V M Krutiakov Izvestiia Akademii nauk SSSR. Seriia biologicheskaia new
? new
Perspectives for the chemotherapy of AIDS. Erik De Clercq Anticancer research pols set
? new
? new
? new
Interactions between human immunodeficiency virus type 1 reverse transcriptase, tRNA primer, and nucleocapsid protein during reverse transcription. M Hsu, Mark A. Wainberg Journal of human virology new
[Current acquisitions in antiviral drugs (anti-HIV)]. Erik De Clercq, Robert Snoeck Journal de pharmacie de Belgique pols set
Discovery, development and characterization of agents active against the AIDS virus. Rudi Pauwels, M P de Bethune, Koen Andries, Paul Stoffels, P Janssen, Erik De Clercq Journal of receptor and signal transduction research pols set
? new
? new
[Photoaffinity modification of human immunodeficiency virus reverse transcriptase with an analog of deoxyuridine-5'-triphosphate, containing an arylazide group]. N V Shcherbik, Svetlana N Khodyreva, V A Vlasov, M I Dobrikov, G M Dymshits, Olga I Lavrik Molekuliarnaia biologiia new
The nature of the DNA substrate influences pre-catalytic conformational changes of DNA polymerase β. J Huang, KS Alnajjar, MM Mahmoud, BE Eckenroth, S Doublie, J Sweasy The Journal of biological chemistry 2018 topics set
Switching between Exonucleolysis and Replication by T7 DNA Polymerase Ensures High Fidelity. TP Hoekstra, M Depken, SN Lin, J Cabanas-Danés, P Gross, RT Dame, EJ Peterman, GJ Wuite Biophysical journal 2017 topics set
Real-time single-molecule studies of the motions of DNA polymerase fingers illuminate DNA synthesis mechanisms. Geraint W Evans, Johannes Hohlbein, Timothy D Craggs, Louise Aigrain, Achillefs N Kapanidis Nucleic acids research 2015 topics set
Mitochondrial Single-stranded DNA-binding Proteins Stimulate the Activity of DNA Polymerase γ by Organization of the Template DNA. Grzegorz L Ciesielski, Oya Bermek, Fernando A Rosado-Ruiz, Stacy L Hovde, Orrin J Neitzke, Jack D Griffith, Laurie S Kaguni The Journal of biological chemistry 2015 topics set
DNA polymerase 3'→5' exonuclease activity: Different roles of the beta hairpin structure in family-B DNA polymerases. Hariyanto Darmawan, Melissa Harrison, Linda J Reha-Krantz DNA repair 2015 new
Highly efficient one-step PCR-based mutagenesis technique for large plasmids using high-fidelity DNA polymerase. H Liu, R Ye, Y Y Wang Genetics and molecular research : GMR 2015 new
A novel approach for rapid detection of bacterially contaminated platelet concentrates via sensitive measurement of microbial DNA polymerase activity. Daniel R Zweitzig, Nichol M Riccardello, John M Pester, Rebecca Jeanmonod, Mark J Kopnitsky, S Mark O'Hara Transfusion 2014 new
Fluorescence resonance energy transfer studies of DNA polymerase β: the critical role of fingers domain movements and a novel non-covalent step during nucleotide selection. Jamie B Towle-Weicksel, Shibani Dalal, Christal D Sohl, Sylvie Doublié, Karen S Anderson, Joann B Sweasy The Journal of biological chemistry 2014 new
Sustained active site rigidity during synthesis by human DNA polymerase μ. Andrea F Moon, John M Pryor, Dale A Ramsden, Thomas A Kunkel, Katarzyna Bebenek, Lars C Pedersen Nature structural & molecular biology 2014 new
In vivo evidence that phenylalanine 171 acts as a molecular brake for translesion DNA synthesis across benzo[a]pyrene DNA adducts by human DNA polymerase κ. Akira Sassa, Tetsuya Suzuki, Yuki Kanemaru, Naoko Niimi, Hirofumi Fujimoto, Atsushi Katafuchi, Petr Grúz, Manabu Yasui, Ramesh C Gupta, Francis Johnson, Toshihiro Ohta, Masamitsu Honma, Noritaka Adachi, Takehiko Nohmi DNA repair 2014 new
Structural basis for processive DNA synthesis by yeast DNA polymerase ɛ. M Hogg, Pia Osterman, Göran O Bylund, Rais A Ganai, Else-Britt Lundström, AE Sauer-Eriksson, Erik Johansson Nature structural & molecular biology 2014 topics set
Crystal structure of the vaccinia virus DNA polymerase holoenzyme subunit D4 in complex with the A20 N-terminal domain. Céline Contesto-Richefeu, Nicolas Tarbouriech, Xavier Brazzolotto, Stéphane Betzi, Xavier Morelli, Wim P Burmeister, Frédéric Iseni PLoS pathogens 2014 new
A hot start alternative for high-fidelity DNA polymerase amplification mediated by quantum dots. Fuming Sang, Yang Yang, Ying Lin, Zhizhou Zhang Acta biochimica et biophysica Sinica 2014 new
Enhancing the processivity of a family B-type DNA polymerase of Thermococcus onnurineus and application to long PCR. Yun Jae Kim, Hyun Sook Lee, Suk-Tae Kwon, Jung-Hyun Lee, Sung Gyun Kang Biotechnology letters 2014 new
DNA polymerase as a molecular motor and pump. Samudra Sengupta, Michelle M Spiering, Krishna K Dey, Wentao Duan, Debabrata Patra, Peter J Butler, R Dean Astumian, Stephen J Benkovic, Ayusman Sen ACS nano 2014 new
Kinetics, structure, and mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine bypass by human DNA polymerase η. Amritraj Patra, Leslie D Nagy, Qianqian Zhang, Yan Su, Livia Müller, F Peter Guengerich, Martin Egli The Journal of biological chemistry 2014 new
PIP degron proteins, substrates of CRL4Cdt2, and not PIP boxes, interfere with DNA polymerase η and κ focus formation on UV damage. Nikolay Tsanov, Chames Kermi, Philippe Coulombe, Siem van der Laan, Dana Hodroj, Domenico Maiorano Nucleic acids research 2014 new
Identification of paired immunoglobulin-like type 2 receptor α as hepatitis B virus DNA polymerase transactivated protein 1 interacting proteins. Yong-Zhi Lun, Qing Chi, Xue-Lei Wang, Fang Wang, Wen Sui Molecular medicine reports 2014 new
Nucleotide selection by the Y-family DNA polymerase Dpo4 involves template translocation and misalignment. Alfonso Brenlla, Radoslaw P Markiewicz, David Rueda, Louis J Romano Nucleic acids research 2014 new
DNA polymerase preference determines PCR priming efficiency. Wenjing Pan, Miranda Byrne-Steele, Chunlin Wang, Stanley Lu, Scott Clemmons, Robert J Zahorchak, Jian Han BMC biotechnology 2014 new
A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome. Aline C Simon, Jin C Zhou, Rajika L Perera, Frederick van Deursen, Cecile Evrin, Marina E Ivanova, Mairi L Kilkenny, Ludovic Renault, Svend Kjaer, Dijana Matak-Vinković, Karim Labib, Alessandro Costa, Luca Pellegrini Nature 2014 new
Look Ma, no PCNA: how DNA polymerase ε synthesizes long stretches of DNA without a processivity factor. Karl E Zahn, Sylvie Doublié Nature structural & molecular biology 2014 new
The stability of Taq DNA polymerase results from a reduced entropic folding penalty; identification of other thermophilic proteins with similar folding thermodynamics. Chin-Chi Liu, Vince J LiCata Proteins 2014 new
Observing a DNA polymerase choose right from wrong. Bret D Freudenthal, William A Beard, David D Shock, Samuel H Wilson Cell 2013 topics set
Understanding the loss-of-function in a triple missense mutant of DNA polymerase β found in prostate cancer. Changlong An, William A Beard, D Chen, Samuel H Wilson, NM Makridakis International journal of oncology 2013 pols set
Structural model of the Y-Family DNA polymerase V/RecA mutasome. Sushil Chandani, Edward L Loechler Journal of molecular graphics & modelling 2013 topics set
Involvement of the reparative DNA polymerase pol X of African swine fever virus in the maintenance of viral genome stability in vivo. Modesto Redrejo-Rodríguez, Javier M Rodríguez, Cristina Suárez, José Salas, María L Salas Journal of virology 2013 pols set
Inhibitory effects of myricetin on mammalian DNA polymerase, topoisomerase and human cancer cell proliferation. Kazuaki Shiomi, Isoko Kuriyama, Hiromi Yoshida, Yoshiyuki Mizushina Food chemistry 2013 topics set
Inhibitory effects of α-mangostin on mammalian DNA polymerase, topoisomerase, and human cancer cell proliferation. Yoshiyuki Mizushina, Isoko Kuriyama, Tatsuo Nakahara, Yoshihito Kawashima, Hiromi Yoshida Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 topics set
Muscle-specific overexpression of the catalytic subunit of DNA polymerase γ induces pupal lethality in Drosophila melanogaster. Francisco Martínez-Azorín, Manuel Calleja, Rosana Hernández-Sierra, Carol L Farr, Laurie S Kaguni, Rafael Garesse Archives of insect biochemistry and physiology 2013 topics set
Replication, Repair and Translesion Polymerase Bypass of N6-Oxopropenyl-2'-deoxyadenosine. Leena Maddukuri, Sarah C Shuck, Robert Lawton Eoff, Linlin Zhao, Carmelo J Rizzo, F Peter Guengerich, Lawrence J Marnett Biochemistry 2013 complete Brad Langhorst
Dancing with chemical formulae of antivirals: a personal account. Erik De Clercq Biochemical pharmacology 2013 new
A high-throughput and quantitative method to assess the mutagenic potential of translesion DNA synthesis. DJ Taggart, Terry L Camerlengo, Jason K Harrison, Shanen M Sherrer, Ajay K Kshetry, John-Stephen Taylor, Kun Huang, Zucai Suo Nucleic acids research 2013 topics set
Single-Molecule Investigation of Substrate Binding Kinetics and Protein Conformational Dynamics of a B-Family Replicative DNA Polymerase. Brian A Maxwell, Zucai Suo The Journal of biological chemistry 2013 new
Following DNA Chain Extension and Protein Conformational Changes in Crystals of a Y-Family DNA Polymerase via Raman Crystallography. Shirly J Espinoza-Herrera, Vineet Gaur, Zucai Suo, Paul R Carey Biochemistry 2013 topics set
Extension into the entrance channel of HIV-1 reverse transcriptase-Crystallography and enhanced solubility. Mariela Bollini, Kathleen M Frey, José A Cisneros, Krasimir A Spasov, Kalyan Das, Joseph David Bauman, Edward Arnold, Karen S Anderson, William L Jorgensen Bioorganic & medicinal chemistry letters 2013 topics set
Structure and functional analysis of the BRCT domain of translesion synthesis DNA polymerase Rev1. John M Pryor, Lokesh Gakhar, M Todd Washington Biochemistry 2013 new
Yeast pol4 promotes tel1-regulated chromosomal translocations. José F Ruiz, Benjamin Pardo, Guillermo Sastre-Moreno, Andrés Aguilera, Luis Blanco PLoS genetics 2013 pols set
Basis for the Early and Preferential Selection of the E138K Substitution in HIV-1 Reverse Transcriptase with Etravirine. Matthew McCallum, Maureen Oliveira, Ruxandra-Ilinca Ibanescu, Victor G Kramer, Daniela D Moisi, Eugene L Asahchop, Bluma G Brenner, Richard Harrigan, Hongtao Xu, Mark A. Wainberg Antimicrobial agents and chemotherapy 2013 pols set
dNTP-dependent conformational transitions in the fingers subdomain of Klentaq1 DNA polymerase: insights into the role of the "nucleotide-binding" state. Paul J Rothwell, William J Allen, Evangelos Sisamakis, Stanislav Kalinin, Suren Felekyan, Jerker Widengren, Gabriel Waksman, Claus A M Seidel The Journal of biological chemistry 2013 pols set
Development of noninvasive prenatal diagnosis of trisomy 21 by RT-MLPA with a new set of SNP markers. Pei-Qiong Li, Jun Zhang, Jian-Hui Fan, Yuan-Zhi Zhang, Hong-Ying Hou Archives of gynecology and obstetrics 2013 complete Hong-Ying Hou*
N(1),N(3)-disubstituted uracils as nonnucleoside inhibitors of HIV-1 reverse transcriptase. Mikhail S Novikov, Vladimir T Valuev-Elliston, Denis A Babkov, Maria P Paramonova, Alexander V Ivanov, Sergey A Gavryushov, Anastasia L Khandazhinskaya, Sergey N Kochetkov, Christophe Pannecouque, Graciela Andrei, Robert Snoeck, Jan Balzarini, Katherine L Seley-Radtke Bioorganic & medicinal chemistry 2013 pols set
Inhibitory effects of low molecular weight polyphenolics from Inonotus obliquus on human DNA topoisomerase activity and cancer cell proliferation. Isoko Kuriyama, Yuki Nakajima, Hiroshi Nishida, Tetsuya Konishi, Toshifumi Takeuchi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Molecular medicine reports 2013 new
Insights into the Conformation of Aminofluorene-dG Adduct in a DNA Polymerase Active Site. Vaidya Ganessan Vaidyanathan, Fengting Liang, William A Beard, David D Shock, Samuel H Wilson, Bongsup P Cho The Journal of biological chemistry 2013 pols set
The mechanism of human tyrosyl-DNA phosphodiesterase 1 in the cleavage of AP site and its synthetic analogs. Natalia A Lebedeva, Nadejda I Rechkunova, Alexander A Ishchenko, Murat Saparbaev, Olga I Lavrik DNA repair 2013 topics set
Mechanism for priming DNA synthesis by yeast DNA Polymerase α. Rajika L Perera, R Torella, Sebastian Klinge, Mairi L Kilkenny, JD Maman, Luca Pellegrini eLife 2013 topics set
Distinctive effects of domain deletions on the manganese-dependent DNA polymerase and DNA phosphorylase activities of Mycobacterium smegmatis polynucleotide phosphorylase. Mihaela-Carmen Unciuleac, Stewart Shuman Biochemistry 2013 pols set
Hepatocytes transduced with human TERT gene acquire a prolonged lifespan in culture and retain permissiveness to hepatitis B virus. L P Lv, Y L Kong, F Yan, P Ma, X P Zhou, Y Y Zhang, D Q Wen, X L Yu, H Y Zhang, H Zhou, J B Xu Acta virologica 2013 topics set
Hypersusceptibility mechanism of Tenofovir-resistant HIV to EFdA. Eleftherios Michailidis, Emily M Ryan, Atsuko Hachiya, Karen A Kirby, Bruno Marchand, Maxwell D Leslie, Andrew D Huber, Yee Tsuey Ong, Jacob C Jackson, Kamalendra Singh, Eiichi N Kodama, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos Retrovirology 2013 pols set
Fidelity, mismatch extension, and proofreading activity of the Plasmodium falciparum apicoplast DNA polymerase. Bentley M Wingert, Eric E Parrott, Scott W Nelson Biochemistry 2013 new
DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation. Rémy Bétous, Marie-Jeanne Pillaire, Laura Pierini, Siem van der Laan, Bénédicte Recolin, Emma Ohl-Séguy, Caixia Guo, Naoko Niimi, Petr Grúz, Takehiko Nohmi, Errol C Friedberg, Christophe Cazaux, Domenico Maiorano, Jean-Sébastien Hoffmann The EMBO journal 2013 new
Novel inhibition of archaeal family-D DNA polymerase by uracil. Tomas T Richardson, Louise Gilroy, Yoshizumi Ishino, Bernard A Connolly, Ghislaine Henneke Nucleic acids research 2013 new
DNA polymerase POLQ and cellular defense against DNA damage. Matthew J Yousefzadeh, Richard D Wood DNA repair 2013 new
Ring-opening of the γ-OH-PdG adduct promotes error-free bypass by the Sulfolobus solfataricus DNA polymerase Dpo4. Ganesh Shanmugam, Irina G Minko, Surajit Banerjee, Plamen P Christov, Ivan D Kozekov, Carmelo J Rizzo, R Stephen Lloyd, Martin Egli, Michael P Stone Chemical research in toxicology 2013 new
First-passage problems in DNA replication: effects of template tension on stepping and exonuclease activities of a DNA polymerase motor. Ajeet K Sharma, Debashish Chowdhury Journal of physics. Condensed matter : an Institute of Physics journal 2013 new
The hepatitis B virus ribonuclease h is sensitive to inhibitors of the human immunodeficiency virus ribonuclease h and integrase enzymes. John E Tavis, Xiaohong Cheng, Yuan Hu, Michael Totten, Feng Cao, Eleftherios Michailidis, Rajeev Aurora, Marvin J Meyers, E Jon Jacobsen, Michael A. Parniak, Stefan G Sarafianos PLoS pathogens 2013 topics set
Design, Synthesis, and Evaluation of WC5 Analogues as Inhibitors of Human Cytomegalovirus Immediate-Early 2 Protein, a Promising Target for Anti-HCMV Treatment. Serena Massari, Beatrice Mercorelli, Luca Sancineto, Stefano Sabatini, Violetta Cecchetti, Giorgio Gribaudo, Giorgio Palù, Christophe Pannecouque, Arianna Loregian, Oriana Tabarrini ChemMedChem 2013 topics set
Expanding the Scope of Human DNA Polymerase λ and β Inhibitors. Tobias Strittmatter, Anette Brockmann, Moritz Pott, Annika Hantusch, Thomas Brunner, Andreas Marx ACS chemical biology 2013 topics set
The preferential selection of K65R in HIV-1 subtype C is attenuated by nucleotide polymorphisms at thymidine analogue mutation sites. Cédric F Invernizzi, Dimitrios Coutsinos, Maureen Oliveira, Rita S Schildknecht, Hongtao Xu, Simani Gaseitswe, Daniela D Moisi, Bluma G Brenner, Mark A. Wainberg The Journal of antimicrobial chemotherapy 2013 pols set
NMR mapping of PCNA interaction with translesion synthesis DNA polymerase Rev1 mediated by Rev1-BRCT domain. Yulia Pustovalova, Mark W Maciejewski, Dmitry M Korzhnev Journal of molecular biology 2013 new
The REV7 subunit of DNA polymerase ζ is essential for primordial germ cell maintenance in the mouse. Naoki Watanabe, Shinji Mii, Naoya Asai, Masato Asai, Kaoru Niimi, Kaori Ushida, Takuya Kato, Atsushi Enomoto, Hideshi Ishii, Masahide Takahashi, Yoshiki Murakumo The Journal of biological chemistry 2013 new
Mutations in HIV-1 reverse transcriptase cause misfolding and miscleavage by the viral protease. Linda L Dunn, Paul L Boyer, Patrick K Clark, Stephen H Hughes Virology 2013 pols set
[Effect of Mn(II) on the error-prone DNA polymerase iota activity in extracts from human normal and tumor cells]. A V Lakhin, A S Efremova, Irina V Makarova, E E Grishina, S I Shram, Vyacheslav Z Tarantul, Leonid V Gening Molekuliarnaia genetika, mikrobiologiia i virusologiia 2013 topics set
DNA synthesis by Pol η promotes fragile site stability by preventing under-replicated DNA in mitosis. Valérie Bergoglio, Anne-Sophie Boyer, Erin Walsh, Valeria Naim, Gaëlle Legube, Marietta Y W T Lee, Laurie Rey, Filippo Rosselli, Christophe Cazaux, Kristin A Eckert, Jean-Sébastien Hoffmann The Journal of cell biology 2013 new
Alteration in the cavity size adjacent to the active site of RB69 DNA polymerase changes its conformational dynamics. Shuangluo Xia, Marcus Wood, Michael J Bradley, Enrique M De La Cruz, William H Konigsberg Nucleic acids research 2013 topics set
Replicative DNA polymerases. Erik Johansson, Nicholas Dixon Cold Spring Harbor perspectives in biology 2013 new
Impact of macromolecular crowding on DNA replication. Barak Akabayov, Sabine R Akabayov, Seung-Joo Lee, Gerhard Wagner, Charles C Richardson Nature communications 2013 pols set
A cyclobutane thymine-N4-methylcytosine dimer is resistant to hydrolysis but strongly blocks DNA synthesis. Junpei Yamamoto, Tomoko Oyama, Tomohiro Kunishi, Chikahide Masutani, Fumio Hanaoka, Shigenori Iwai Nucleic acids research 2013 topics set
Pin1 interacts with the Epstein-Barr virus DNA polymerase catalytic subunit and regulates viral DNA replication. Yohei Narita, Takayuki Murata, Akihide Ryo, Daisuke Kawashima, Atsuko Sugimoto, Teru Kanda, Hiroshi Kimura, Tatsuya Tsurumi Journal of virology 2013 pols set
A structural role for the PHP domain in E. coli DNA polymerase III. Tiago Barros, Joel Guenther, Brian A Kelch, Jordan Anaya, Arjun Prabhakar, Mike E O'Donnell, John Kuriyan, Meindert H Lamers BMC structural biology 2013 new
A plasmid-based lacZα gene assay for DNA polymerase fidelity measurement. Brian J Keith, Stanislaw K Jozwiakowski, Bernard A Connolly Analytical biochemistry 2013 complete Brad Langhorst
The UmuC subunit of the E. coli DNA polymerase V shows a unique interaction with the β-clamp processivity factor. Atif A Patoli, Jody A Winter, Karen A Bunting BMC structural biology 2013 new
Removal of misincorporated ribonucleotides from prokaryotic genomes: an unexpected role for nucleotide excision repair. Alexandra Vaisman, John P McDonald, Donald Huston, Wojciech Kuban, Lili Liu, Bennett Van Houten, Roger Woodgate PLoS genetics 2013 partial results
Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses. Julie K Horton, Donna F Stefanick, Natalie R Gassman, Jason G Williams, Scott A Gabel, Matthew J Cuneo, Rajendra Prasad, Padmini S Kedar, Eugene F DeRose, Esther W Hou, Robert E London, Samuel H Wilson DNA repair 2013 new
Cycloartenyl trans-ferulate, a component of the bran byproduct of sake-brewing rice, inhibits mammalian DNA polymerase and suppresses inflammation. Yoshiyuki Mizushina, Isoko Kuriyama, Asahi Yamazaki, Takahiro Akashi, Hiromi Yoshida Food chemistry 2013 new
An in-frame deletion at the polymerase active site of POLD1 causes a multisystem disorder with lipodystrophy. Michael N Weedon, Sian Ellard, Marc J Prindle, Richard Caswell, Hana Lango Allen, Richard Oram, Koumudi Godbole, Chittaranjan S Yajnik, Paolo Sbraccia, Giuseppe Novelli, Peter Turnpenny, Emma McCann, Kim Jee Goh, Yukai Wang, Jonathan Fulford, Laura J McCulloch, David B Savage, Stephen O'Rahilly, Katarina Kos, Lawrence A Loeb, Robert K Semple, Andrew T Hattersley Nature genetics 2013 new
The excision of 3' penultimate errors by DNA polymerase I and its role in endonuclease V-mediated DNA repair. Chia-Chia Lee, Ya-Chien Yang, Steven D Goodman, Chien-Ju Lin, Yi-An Chen, Yi-Ting Wang, Wern-Cherng Cheng, Liang-In Lin, Woei-Horng Fang DNA repair 2013 new
An iron-sulfur cluster in the polymerase domain of yeast DNA polymerase ε Rinku Jain, Eva S Vanamee, Boris G Dzikovski, Angeliki Buku, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Journal of molecular biology 2013 topics set
The Nucleoside Reverse Transcriptase Inhibitors, Nonnucleoside Reverse Transcriptase Inhibitors, and Protease Inhibitors in the Treatment of HIV Infections (AIDS). Erik De Clercq Advances in pharmacology (San Diego, Calif.) 2013 pols set
ATR-Chk1-APC/CCdh1-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress. Masayuki Yamada, Kenji Watanabe, Martin Mistrik, Eva Vesela, Iva Protivankova, Niels Mailand, Myunghee Lee, Hisao Masai, Jiri Lukas, Jiri Bartek Genes & development 2013 topics set
Molecular dynamics study of HIV-1 RT-DNA-Nevirapine complexes explains NNRTI inhibition, and resistance by connection mutations. R S K Vijayan, Edward Arnold, Kalyan Das Proteins 2013 pols set
Novel DNA polymerase mutations conferring cytomegalovirus resistance: input of BAC-recombinant phenotyping and 3D model. Sébastien Hantz, Sébastien Cotin, Eva Borst, Anthony Couvreux, Arielle Salmier, Isabelle Garrigue, Pierre Merville, Catherine Mengelle, Michel Attal, Martin Messerle, Sophie Alain Antiviral research 2013 topics set
Analysis of Ig gene hypermutation in Ung(-/-)Polh(-/-) mice suggests that UNG and A:T mutagenesis pathway target different U:G lesions. Shuyin Li, Yaofeng Zhao, Ji-Yang Wang Molecular immunology 2013 new
Detecting allosteric sites of HIV-1 reverse transcriptase by X-ray crystallographic fragment screening. Joseph David Bauman, Disha Patel, Chhaya Dharia, Marc Fromer, Sameer Ahmed, Yulia Volovik Frenkel, J Thomas Eck, William C Ho, Kalyan Das, Aaron J Shatkin, Edward Arnold Journal of medicinal chemistry 2013 pols set
The E295K cancer variant of human polymerase beta favors the mismatch conformational pathway during nucleotide selection. Brian E Eckenroth, Jamie B Towle-Weicksel, Joann B Sweasy, Sylvie Doubli Eacute The Journal of biological chemistry 2013 topics set
Inhibition of repair-related DNA polymerases by vitamin Ks, their related quinone derivatives and associated inflammatory activity (Review). Yoshiyuki Mizushina, Shin Nishiumi, Masayuki Nishida, Hiromi Yoshida, Takeshi Azuma, Masaru Yoshida International journal of oncology 2013 new
DNA polymerase ζ as a potential biomarker of chemoradiation resistance and poor prognosis for cervical cancer. Ting-Yan Shi, Li Yang, Gong Yang, Xiao-Yu Tu, Xiaohua Wu, Xi Cheng, Qingyi Wei Medical oncology (Northwood, London, England) 2013 topics set
Measuring and modeling the kinetics of individual DNA-DNA polymerase complexes on a nanopore. Hongyun Wang, Nicholas Hurt, William B Dunbar ACS nano 2013 complete Brad Langhorst
A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli. Amit Sharma, J Kottur, N Narayanan, Deepak T Nair Nucleic acids research 2013 pols set
PCNA trimer instability inhibits translesion synthesis by DNA polymerase η and by DNA polymerase δ. Lynne M Dieckman, M Todd Washington DNA repair 2013 topics set
Molecular Basis for DNA Double-Strand Break Annealing and Primer Extension by an NHEJ DNA Polymerase. Nigel C Brissett, Maria Jose Martin, Edward J Bartlett, Julie Bianchi, Luis Blanco, Aidan J Doherty Cell reports 2013 topics set
Carcinogenic adducts induce distinct DNA polymerase binding orientations. KB Vrtis, RP Markiewicz, Louis J Romano, David Rueda Nucleic acids research 2013 new
Snapshot of a DNA polymerase while incorporating two consecutive C5-modified nucleotides. Samra Obeid, H Bußkamp, Wolfram Welte, Kay Diederichs, Andreas Marx Journal of the American Chemical Society 2013 topics set
The Architecture of Yeast DNA Polymerase ζ Yacob Gómez-Llorente, Radhika Malik, Rinku Jain, Jayati Roy Choudhury, Robert E Johnson, Louise Prakash, Satya Prakash, Iban Ubarretxena-Belandia, Aneel K Aggarwal Cell reports 2013 topics set
Ultra-Sensitive Sequencing Reveals an Age-Related Increase in Somatic Mitochondrial Mutations That Are Inconsistent with Oxidative Damage. Scott R Kennedy, Jesse J Salk, Michael W Schmitt, Lawrence A Loeb PLoS genetics 2013 topics set
Effects of 4' - and 2-Substitutions on the Bioactivity of 4' -Ethynyl-2-Fluoro-2' -Deoxyadenosine. Karen A Kirby, Eleftherios Michailidis, Tracy L Fetterly, MA Steinbach, Kamalendra Singh, Bruno Marchand, Maxwell D Leslie, Ariel N Hagedorn, Eiichi N Kodama, Victor E Marquez, Stephen H Hughes, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos Antimicrobial agents and chemotherapy 2013 topics set
Strategic Combination of DNA-Damaging Agent and PARP Inhibitor Results in Enhanced Cytotoxicity. Julie K Horton, Samuel H Wilson Frontiers in oncology 2013 new
Dpb2 integrates the leading-strand DNA polymerase into the eukaryotic replisome. Sugopa Sengupta, Frederick van Deursen, Giacomo De Piccoli, Karim Labib Current biology : CB 2013 topics set
Structure-function analysis of ribonucleotide bypass by B family DNA replicases. Anders R Clausen, Michael S Murray, Andrew R Passer, Lars C Pedersen, Thomas A Kunkel Proceedings of the National Academy of Sciences of the United States of America 2013 topics set
Inhibition of HIV-1 Reverse Transcriptase-Catalyzed Synthesis by Intercalated DNA Benzo[a]Pyrene 7,8-Dihydrodiol-9,10-Epoxide Adducts. Parvathi Chary, William A Beard, Samuel H Wilson, R Stephen Lloyd PloS one 2013 topics set
Histone Lysine-Specific Methyltransferases and Demethylases in Carcinogenesis: New Targets for Cancer Therapy and Prevention. Xuejiao Tian, Saiyang Zhang, Hong-Min Liu, Yan-Bing Zhang, Christopher A Blair, Dan Mercola, Paolo Sassone-Corsi, Xiaolin Zi Current cancer drug targets 2013 topics set
Rapid detection of orf virus by loop-mediated isothermal amplification based on the DNA polymerase gene. Jinming Li, Deguang Song, Wenqi He, Yingfu Bao, Rongguang Lu, Gaoli Su, Gaili Wang, Huijun Lu, Kui Zhao, Feng Gao Archives of virology 2013 topics set
Structure and Function of an RNA-Reading Thermostable DNA Polymerase. Nina Blatter, Konrad Bergen, O Nolte, Wolfgang Welte, Kay Diederichs, J Mayer, M Wieland, Andreas Marx Angewandte Chemie (International ed. in English) 2013 topics set
Effect of Smilax china L.-containing serum on the expression of POLD1 mRNA in human hepatocarcinoma SMMC-7721 cells. Bo Cao, Zihan Zhang, Yuqin Zhang, Jinming Li, Gang Liang, Jianghong Ling Experimental and therapeutic medicine 2013 pols set
Preferential D-loop extension by a translesion DNA polymerase underlies error-prone recombination. Richard T Pomerantz, Isabel Kurth, Myron F Goodman, Mike E O'Donnell Nature structural & molecular biology 2013 topics set
Dual inhibition of DNA polymerase PolC and protein tyrosine phosphatase CpsB uncovers a novel antibiotic target. Alistair J Standish, Angela A Salim, Robert J Capon, Renato Morona Biochemical and biophysical research communications 2013 topics set
Involvement of AtPolλ in repair of high salt and DNA cross linking agent induced double strand breaks in Arabidopsis thaliana. Sujit Roy, Swarup Roy Choudhury, Dibyendu Narayan SenGupta, Kali Pada Das Plant physiology 2013 pols set
Molecular design, synthesis and biological evaluation of BP-O-DAPY and O-DAPY derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors. Shiqiong Yang, Christophe Pannecouque, Dirk Daelemans, Xiao-Dong Ma, Yang Liu, Fen-Er Chen, Erik De Clercq European journal of medicinal chemistry 2013 pols set
Spectroscopic analysis of polymerization and exonuclease proofreading by a high-fidelity DNA polymerase during translesion DNA synthesis. Babho Devadoss, Irene Lee, Anthony J Berdis Biochimica et biophysica acta 2013 topics set
Structural changes in the hydrophobic hinge region adversely affect the activity and fidelity of the I260Q mutator of DNA polymerase ß Chelsea L Gridley, Sneha Rangarajan, Susan J Firbank, Shibani Dalal, Joann B Sweasy, Joachim Jaeger Biochemistry 2013 topics set
Clicking 3'-azidothymidine into novel potent inhibitors of human immunodeficiency virus. Venkata Ramana Sirivolu, Sanjeev Kumar V Verneka, Tatiana Ilina, Nataliya S Myshakina, Michael A. Parniak, Zhengqiang Wang Journal of medicinal chemistry 2013 topics set
RNA pathogen detection with one-step reverse transcription PCR and strand-displacement based signal amplification. Feng Du, Frank Streckenbach, Haodong Chen, Xin Huang, Zhuo Tang, Andreas Marx The Analyst 2013 topics set
DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures. Matthew R Northam, Elizabeth A Moore, Tony M Mertz, Sara K Binz, Carrie M W Stith, Elena I Stepchenkova, Kathern L Wendt, Peter M J Burgers, Polina V Shcherbakova Nucleic acids research 2013 topics set
Discovery of Piperidine-Linked Pyridine Analogues as Potent Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors. Xuwang Chen, Yuanyuan Li, Shufang Ding, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Huiqing Liu, Xinyong Liu ChemMedChem 2013 topics set
Amino acid substitution in the active site of DNA polymerase β explains the energy barrier of the nucleotidyl transfer reaction. Vinod K Batra, Lalith Perera, Ping Lin, David D Shock, William A Beard, Lars C Pedersen, Lee G Pedersen, Samuel H Wilson Journal of the American Chemical Society 2013 topics set
DNA polymerase δ stalls on telomeric lagging strand templates independently from G-quadruplex formation. JD Lormand, N Buncher, CT Murphy, P Kaur, Marietta Y W T Lee, P Burgers, Hongyun Wang, Thomas A Kunkel, Patricia L Opresko Nucleic acids research 2013 topics set
The Human Tim/Tipin Complex Directly Interacts with DNA Polymerase {epsilon} and Stimulates its Synthetic Activity. Valentina Aria, Mariarita De Felice, Roberta Di Perna, Shuji Uno, Hisao Masai, Juhani E Syvaoja, Barbara van Loon, Ulrich Hubscher, Francesca M Pisani The Journal of biological chemistry 2013 topics set
A non-catalytic role of DNA polymerase η in recruiting Rad18 and promoting PCNA monoubiquitination at stalled replication forks. Michael Durando, Satoshi Tateishi, Cyrus Vaziri Nucleic acids research 2013 topics set
DNA Polymerase λ Inactivation by Oxidized Abasic Sites. Adam J Stevens, Lirui Guan, Katarzyna Bebenek, Thomas A Kunkel, Marc M Greenberg Biochemistry 2013 topics set
Kinetic Mechanism of DNA Polymerization Catalyzed by Human DNA Polymerase ε Walter J Zahurancik, Seth J Klein, Zucai Suo Biochemistry 2013 topics set
Dual Role of φ29 DNA Polymerase Lys529 in Stabilisation of the DNA Priming-Terminus and the Terminal Protein-Priming Residue at the Polymerisation Site. Alicia Del Prado, José María Lázaro, Laurentino Villar, Margarita Salas, Miguel de Vega PloS one 2013 topics set
Dynamics of enzymatic interactions during short flap human Okazaki fragment processing by two forms of human DNA polymerase δ Szu Hua Sharon Lin, Xiaoxiao Wang, Sufang Zhang, Zhenzhong Zhang, Ernest Y C Lee, Marietta Y W T Lee DNA repair 2013 pols set
Design, Synthesis, and Biological Evaluation of Novel 3,5-Disubstituted-1,2,6-Thiadiazine-1,1-Dione Derivatives as HIV-1 NNRTIs. Ye Tian, Diwakar Rai, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Huiqing Liu, Xinyong Liu Chemical biology & drug design 2013 topics set
Competitive Fitness during Feast and Famine: How SOS DNA Polymerases Influence Physiology and Evolution in Escherichia coli. Christopher H Corzett, Myron F Goodman, Steven E Finkel Genetics 2013 pols set
A synthetic substrate of DNA polymerase deviating from the bases, sugar, and leaving group of canonical deoxynucleoside triphosphates. Mi-Yeon Jang, Xiao-Ping Song, Mathy Froeyen, Philippe Marlière, Eveline Lescrinier, Jef Rozenski, Piet Herdewijn Chemistry & biology 2013 new
Biochemical, cellular and molecular identification of DNA polymerase α in yeast mitochondria Jean-Paul Lasserre, Jacqueline Plissonneau, Christophe Velours, Marc Bonneu, Simon Litvak, Patricia Laquel, M. Castroviejo Biochem J 2013 new
Discrete interactions between bacteriophage T7 primase-helicase and DNA polymerase drive the formation of a priming complex containing two copies of DNA polymerase. Jamie R Wallen, Jerzy Majka, Tom Ellenberger Biochemistry 2013 new
Development of a genome-wide random mutagenesis system using proofreading-deficient DNA polymerase δ in the methylotrophic yeast Hansenula polymorpha. Oh Cheol Kim, Sang-Yoon Kim, Dong Hyeon Hwang, Doo-Byoung Oh, Hyun Ah Kang, Ohsuk Kwon Journal of microbiology and biotechnology 2013 topics set
Circulating tumor cells as a surrogate marker for determining clinical outcome to mFOLFOX chemotherapy in patients with stage III colon cancer. C-Y Lu, H-L Tsai, Y-H Uen, H-M Hu, C-W Chen, T-L Cheng, S-R Lin, J-Y Wang British journal of cancer 2013 new
Oxidative stress-induced mutagenesis in single-strand DNA occurs primarily at cytosines and is DNA polymerase zeta-dependent only for adenines and guanines. Natalya P Degtyareva, Lanier Heyburn, Joan F Sterling, Michael A Resnick, Dmitry A Gordenin, Paul W Doetsch Nucleic acids research 2013 new
The Effect of Mutations at Position E138 in HIV-1 Reverse Transcriptase and their Interactions with the M184I Mutation in Defining Patterns of Resistance to the Non-Nucleoside Reverse Transcriptase Inhibitors Rilpivirine and Etravirine. Hong-Tao Xu, Susan P Colby-Germinario, Eugene L Asahchop, Maureen Oliveira, Matthew McCallum, Susan M Schader, Yingshan Han, Yudong Quan, Stefan G Sarafianos, Mark A. Wainberg Antimicrobial agents and chemotherapy 2013 topics set
Biochemical, cellular and molecular identification of DNA polymerase α in yeast mitochondria. Jean-Paul Lasserre, Jacqueline Plissonneau, Christophe Velours, Marc Bonneu, Simon Litvak, Patricia Laquel, Michel Castroviejo Biochimie 2013 new
A Substitution in the Fingers Domain of DNA Polymerase Delta Reduces Fidelity by Altering Nucleotide Discrimination in the Catalytic Site. Marc J Prindle, Michael W Schmitt, Fabio Parmeggiani, Lawrence A Loeb The Journal of biological chemistry 2013 new
RecA acts as a switch to regulate polymerase occupancy in a moving replication fork. Chiara Indiani, Meghna Patel, Myron F Goodman, Mike E O'Donnell Proceedings of the National Academy of Sciences of the United States of America 2013 topics set
Dual role for mammalian DNA polymerase ζ in maintaining genome stability and proliferative responses. Sabine S Lange, Ella Bedford, Shelley Reh, John P Wittschieben, Steve Carbajal, Donna F Kusewitt, John DiGiovanni, Richard D Wood Proceedings of the National Academy of Sciences of the United States of America 2013 topics set
Improving bioorthogonal protein ubiquitylation by click reaction. Daniel Schneider, Tatjana Schneider, Daniel Rösner, Martin Scheffner, Andreas Marx Bioorganic & medicinal chemistry 2013 new
Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase. Daniel G Kuroda, Joseph David Bauman, J Reddy Challa, Disha Patel, Thomas Troxler, Kalyan Das, Edward Arnold, Robin M Hochstrasser Nature chemistry 2013 pols set
HIV-1 reverse transcriptase and antiviral drug resistance. Part 2. Kalyan Das, Edward Arnold Current opinion in virology 2013 topics set
Dynamics of Hepatitis B Virus Resistance Substitutions Correlates with Virological Response in Lamivudine-Refractory Patients with Entecavir Rescue Monotherapy. Yan Zhang, Song He, Qing-Ling Li, Jin-Jun Guo Virus research 2013 new
Evolution of HIV integrase resistance mutations. Peter K Quashie, Thibault Mesplède, Mark A. Wainberg Current opinion in infectious diseases 2013 new
Increased Learning and Brain Long-Term Potentiation in Aged Mice Lacking DNA Polymerase μ. Daniel Lucas, José M Delgado-García, Beatriz Escudero, Carmen Albo, Ana Aza, Rebeca Acín-Pérez, Yaima Torres, Paz Moreno, José Antonio Enríquez, Enrique Samper, Luis Blanco, Alfonso Fairén, Antonio Bernad, Agnès Gruart PloS one 2013 new
The Exonuclease Activity of the Yeast Mitochondrial DNA Polymerase γ Suppresses Mitochondrial DNA Deletions Between Short Direct Repeats in Saccharomyces cerevisiae. Jeffrey D Stumpf, William C Copeland Genetics 2013 topics set
Synthesis and biological evaluation of pyridazine derivatives as novel HIV-1 NNRTIs. Dongyue Li, Peng Zhan, Huiqing Liu, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu Bioorganic & medicinal chemistry 2013 pols set
Replication of a carcinogenic nitropyrene DNA lesion by human Y-family DNA polymerase. Kevin N Kirouac, Ashis K Basu, Hong Ling Nucleic acids research 2013 topics set
A Multi-targeted Drug Candidate with Dual Anti-HIV and Anti-HSV Activity. Jan Balzarini, Graciela Andrei, Emanuela Balestra, Dana Huskens, Christophe Vanpouille, Andrea Introini, Sonia Zicari, Sandra Liekens, Robert Snoeck, Antonín Holý, CF Perno, Leonid Margolis, Dominique Schols PLoS pathogens 2013 topics set
Dynamics of DNA polymerase I (Klenow fragment) under external force. Ping Xie Journal of molecular modeling 2013 topics set
Optimization of the masking molecule for active-site-protected immobilization of Taq DNA polymerase and its application. Gumjung Lim, Joungmok Kim, Jeong Hee Kim Analytical biochemistry 2013 topics set
Trinucleotide repeat deletion via a unique hairpin bypass by DNA polymerase β and alternate flap cleavage by flap endonuclease 1. Meng Xu, Jonathan Gabison, Yuan Liu Nucleic acids research 2013 topics set
Dynamics of site switching in DNA polymerase. Rajan Lamichhane, Svitlana Y Berezhna, JP Gill, Edwin J C Van der Schans, David P Millar Journal of the American Chemical Society 2013 new
PDIP38 is translocated to the spliceosomes/nuclear speckles in response to UV-induced DNA damage and is required for UV-induced alternative splicing of MDM2. Agnes Wong, Sufang Zhang, Dana Mordue, Joseph M Wu, Zhongtao Zhang, Zbigniew Darzynkiewicz, Ernest Y C Lee, Marietta Y W T Lee Cell cycle (Georgetown, Tex.) 2013 new
HIV-1 reverse transcriptase and antiviral drug resistance. Part 1. Kalyan Das, Edward Arnold Current opinion in virology 2013 topics set
Cellular roles of DNA polymerase beta. Sreerupa Ray, Miriam Rose Menezes, Alireza G Senejani, Joann B Sweasy The Yale journal of biology and medicine 2013 new
Ribonucleotides Are Signals for Mismatch Repair of Leading-Strand Replication Errors. Scott A Lujan, Jessica S Williams, Anders R Clausen, Alan B Clark, Thomas A Kunkel Molecular cell 2013 topics set
PolA1, a putative DNA polymerase I, is coexpressed with PerR and contributes to peroxide stress defenses of group A Streptococcus. Chadia Toukoki, Ioannis Gryllos Journal of bacteriology 2013 topics set
Translesion synthesis past acrolein-derived DNA adducts by human mitochondrial DNA polymerase γ Rajesh Kasiviswanathan, Irina G Minko, R Stephen Lloyd, William C Copeland The Journal of biological chemistry 2013 topics set
Replication-competent infectious hepatitis B virus vectors carrying substantially sized transgenes by redesigned viral polymerase translation. Zihua Wang, Li Wu, Xin Cheng, Shizhu Liu, Baosheng Li, Haijun Li, Fubiao Kang, Junping Wang, Huan Xia, Caiyan Ping, Michael Nassal, Dianxing Sun PloS one 2013 complete Dianxing Sun*
Incorporation of Nucleoside Probes Opposite O(6) -Methylguanine by Sulfolobus solfataricus DNA Polymerase Dpo4: Importance of Hydrogen Bonding. Alessia Stornetta, Todor Angelov, F Peter Guengerich, Shana J Sturla Chembiochem : a European journal of chemical biology 2013 pols set
Fast mitochondrial DNA isolation from mammalian cells for next-generation sequencing. Wilber Quispe-Tintaya, Ryan R White, Vasily N Popov, Jan Vijg, Alexander Y Maslov BioTechniques 2013 topics set
Homocysteine-related hTERT DNA demethylation contributes to shortened leukocyte telomere length in atherosclerosis. Donghong Zhang, Xuemei Wen, Wei Wu, Ermu Xu, Yujuan Zhang, Wei Cui Atherosclerosis 2013 pols set
Mechanism of somatic hypermutation at the WA motif by human DNA polymerase η Yaofeng Zhao, Mark T Gregory, Christian Biertümpfel, Yue-Jin Hua, Fumio Hanaoka, Wei Wen Yang Proceedings of the National Academy of Sciences of the United States of America 2013 topics set
Construction of shRNA expression plasmids for silkworm cell lines using single-stranded DNA and Bst DNA polymerase. Hiromitsu Tanaka Methods in molecular biology (Clifton, N.J.) 2013 pols set
Involvement of DNA polymerase β overexpression in the malignant transformation induced by benzo[a]pyrene. Wei Zhao, Mei Wu, Yanhao Lai, Wenwen Deng, Yuan Liu, Zhenzhong Zhang Toxicology 2013 topics set
Recruitment of DNA polymerase eta by FANCD2 in the early response to DNA damage. Dechen Fu, Fred Duafalia Dudimah, Jun Zhang, Anna Pickering, Jayabal Paneerselvam, Manikandan Palrasu, Hong Wang, Peiwen Fei Cell cycle (Georgetown, Tex.) 2013 topics set
Mouse DNA polymerase kappa has a functional role in the repair of DNA strand breaks. Xiuli Zhang, Lingna Lv, Qian Chen, Fenghua Yuan, Ting Zhang, Yeran Yang, Hui Zhang, Yun Wang, Yan Jia, Liangyue Qian, Benjamin Chen, Yongqing Zhang, Errol C Friedberg, Tie-Shan Tang, Caixia Guo DNA repair 2013 pols set
Novel piperidinylamino-diarylpyrimidine derivatives with dual structural conformations as potent HIV-1 non-nucleoside reverse transcriptase inhibitors. Xuwang Chen, Xin Liu, Qing Meng, Ding Wang, Huiqing Liu, Erik De Clercq, Christophe Pannecouque, Jan Balzarini, Xinyong Liu Bioorganic & medicinal chemistry letters 2013 pols set
Sulfolobus chromatin proteins modulate strand displacement by DNA polymerase B1. Fei Sun, Li Huang Nucleic acids research 2013 pols set
Conformational landscapes of DNA polymerase I and mutator derivatives establish fidelity checkpoints for nucleotide insertion. Johannes Hohlbein, Louise Aigrain, Timothy D Craggs, Oya Bermek, Olga Potapova, Pouya Shoolizadeh, Nigel D F Grindley, Catherine M Joyce, Achillefs N Kapanidis Nature communications 2013 new
Reconstitution of recombination-associated DNA synthesis with human proteins. Jessica L Sneeden, Sara M Grossi, Inger Tappin, Jerard Hurwitz, Wolf-Dietrich Heyer Nucleic acids research 2013 pols set
Significant association of 5p15.33 (TERT-CLPTM1L genes) with lung cancer in Chinese Han population. Zhenhong Zhao, Cong Li, Lixin Yang, Xiaobo Zhang, Xueying Zhao, Xiao Song, Xiaoying Li, Jiucun Wang, Ji Qian, Yajun Yang, Li Jin, Hongyan Chen, Daru Lu Experimental lung research 2013 topics set
Herpes simplex virus 1 DNA polymerase processivity factor UL42 inhibits TNF-α-induced NF-κB activation by interacting with p65/RelA and p50/NF-κB1. Jie Zhang, Shuai Wang, Kezhen Wang, Chunfu Zheng Medical microbiology and immunology 2013 new
A single-molecule approach to DNA replication in Escherichia coli cells demonstrated that DNA polymerase III is a major determinant of fork speed. Tuan Minh Pham, Kang Wei Tan, Yuichi Sakumura, Katsuzumi Okumura, Hisaji Maki, Masahiro Tatsumi Akiyama Molecular microbiology 2013 new
Tissue-engineered allograft intervertebral disc transplantation for the treatment of degenerative disc disease: experimental study in a beagle model. Hongkui Xin, Chao Zhang, Deli Wang, Zhiyuan Shi, Tao Gu, Chaofeng Wang, Jianhong Wu, Yongqing Zhang, Qing He, Dike Ruan Tissue engineering. Part A 2013 new
Functional analysis of Drosophila DNA polymerase ε p58 subunit. Ritsuko Sahashi, Risa Matsuda, Osamu Suyari, Mieko Kawai, Hideki Yoshida, Sue Cotterill, Masamitsu Yamaguchi American journal of cancer research 2013 topics set
DNA polymerase V kinetics support the instructive nature of an oxidized abasic lesion in Escherichia coli. John Ernest V Bajacan, Marc M Greenberg Biochemistry 2013 topics set
Clustered DNA Lesions Containing 5-Formyluracil and AP Site: Repair via the BER System. Ekaterina A Belousova, Inna A Vasil'eva, Nina A Moor, Timofey S Zatsepin, Tatiana S Oretskaya, Olga I Lavrik PloS one 2013 topics set
Systematic Functional Comparative Analysis of Four Single-Stranded DNA-Binding Proteins and Their Affection on Viral RNA Metabolism. Haiyan Shi, Yongqing Zhang, Guohui Zhang, Jinlei Guo, Xun Zhang, Haiyan Song, Jianxin Lv, Jimin Gao, Yuepeng Wang, Litian Chen, Yue Wang PloS one 2013 new
New insights in the ϕ29 terminal protein DNA-binding and host nucleoid localization functions. Isabel Holguera, Modesto Redrejo-Rodríguez, Margarita Salas, Daniel Muñoz-Espín Molecular microbiology 2013 new
Overexpressed DNA Polymerase Iota Regulated by JNK/c-Jun Contributes to Hypermutagenesis in Bladder Cancer. Fenghua Yuan, Zhigang Xu, Mingzhen Yang, Quanfang Wei, Yongqing Zhang, Jin Yu, Yi Zhi, Yang Liu, Zhiwen Chen, Jin Yang PloS one 2013 topics set
Clinical and Molecular Features of POLG-Related Mitochondrial Disease. Jeffrey D Stumpf, Russell P Saneto, William C Copeland Cold Spring Harbor perspectives in biology 2013 pols set
A novel function of CRL4Cdt2: regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phase. Sufang Zhang, Hong Zhao, Zbiegniew Darzynkiewicz, Pengbo Zhou, Zhongtao Zhang, Ernest Y C Lee, Marietta Y W T Lee The Journal of biological chemistry 2013 topics set
Towards new C6-rigid S-DABO HIV-1 reverse transcriptase inhibitors: Synthesis, biological investigation and molecular modeling studies. Hai-Qiu Wu, Zi-Hong Yan, Wen-Xue Chen, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Dirk Daelemans, Christophe Pannecouque Bioorganic & medicinal chemistry 2013 topics set
Expression and mechanism of PinX1 and telomerase activity in the carcinogenesis of esophageal epithelial cells. Jing Zuo, Da-Hu Wang, Yu-Jun Zhang, Liang Liu, Feng-Ling Liu, Wei Liu Oncology reports 2013 topics set
Targeting of the Purine Biosynthesis Host Cell Pathway Enhances the Activity of Tenofovir Against Sensitive and Drug-Resistant HIV-1. A Heredia, CE Davis, MS Reitz, NM Le, MA Wainberg, JS Foulke, LX Wang, RR Redfield The Journal of infectious diseases 2013 topics set
A solution to release twisted DNA during chromosome replication by coupled DNA polymerases. Isabel Kurth, Roxana E Georgescu, Mike E O'Donnell Nature 2013 new
PrimPol, an Archaic Primase/Polymerase Operating in Human Cells. Sara García-Gómez, Aurelio Reyes, María I Martínez-Jiménez, E Sandra Chocrón, Silvana Mourón, Gloria Terrados, Christopher Powell, Eduardo Salido, Juan Méndez, Ian J Holt, Luis Blanco Molecular cell 2013 new
DNA polymerases are error-prone at RecA-mediated recombination intermediates. Richard T Pomerantz, Myron F Goodman, Michael E O'Donnell Cell cycle (Georgetown, Tex.) 2013 topics set
Proofreading exonuclease on a tether: the complex between the E. coli DNA polymerase III subunits α, epsilon, θ and β reveals a highly flexible arrangement of the proofreading domain. Kiyoshi Ozawa, NP Horan, A Robinson, H Yagi, FR Hill, Slobodan Jergic, ZQ Xu, KV Loscha, N Li, M Tehei, Aaron J Oakley, Gottfried Otting, T Huber, Nicholas E Dixon Nucleic acids research 2013 topics set
DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7,8-dihydroguanine bypass. Giovanni Maga, Emmanuele Crespan, Enni Markkanen, Ralph Imhof, Antonia Furrer, Giuseppe Villani, Ulrich Hübscher, Barbara van Loon Proceedings of the National Academy of Sciences of the United States of America 2013 new
Interaction of PARP-2 with DNA structures mimicking DNA repair intermediates and consequences on activity of base excision repair proteins. Mikhail M Kutuzov, Svetlana N Khodyreva, Jean-Christophe Amé, Ekaterina S Ilina, Maria V Sukhanova, Valerie Schreiber, Olga I Lavrik Biochimie 2013 new
Restriction fragment mass polymorphism (RFMP) analysis based on MALDI-TOF mass spectrometry for detecting antiretroviral resistance in HIV-1 infected patients. J-H Lee, Atsuko Hachiya, S-K Shin, J Lee, Hiroyuki Gatanaga, Shinichi Oka, Karen A Kirby, Yee Tsuey Ong, Stefan G Sarafianos, William R Folk, Wangdon Yoo, Sun Pyo Hong, S-O Kim Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2013 pols set
Nuclear transport of Epstein-Barr virus DNA polymerase is dependent on the BMRF1 polymerase processivity factor and molecular chaperone Hsp90. Daisuke Kawashima, Teru Kanda, Takayuki Murata, Shinichi Saito, Atsuko Sugimoto, Yohei Narita, Tatsuya Tsurumi Journal of virology 2013 pols set
Emergence of DNA polymerase ε antimutators that escape error-induced extinction in yeast. Lindsey N Williams, Alan J Herr, Bradley D Preston Genetics 2013 pols set
Interaction between DNA Polymerase β and BRCA1. Aya Masaoka, Natalie R Gassman, Julie K Horton, Padmini S Kedar, Kristine L Witt, Cheryl A Hobbs, Grace E Kissling, Keizo Tano, Kenjiro Asagoshi, Samuel H Wilson PloS one 2013 topics set
Telomeres-structure, function, and regulation. Weisi Lu, Yongqing Zhang, Dan Liu, Zhou Songyang, Ma Wan Experimental cell research 2013 new
Structures of an apo and a binary complex of an evolved archeal B family DNA polymerase capable of synthesising highly cy-dye labelled DNA. Samantha A Wynne, Vitor B Pinheiro, Philipp Holliger, Andrew G W Leslie PloS one 2013 new
DNA polymerase β promoter mutations and transcriptional activity in esophageal squamous cell carcinoma. Min Li, Wenqiao Zang, Yuanyuan Wang, Yuebai Li, Yunyun Ma, Na Wang, Yue Tang, Lulu Liu, Ziming Dong, Guoqiang Zhao Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2013 new
Leukotriene biosynthesis inhibitor MK886 impedes DNA polymerase activity. Amit Ketkar, Maroof Khan Zafar, Leena Maddukuri, Kinrin Yamanaka, Surajit Banerjee, Martin Egli, Jeong-Yun Choi, R Stephen Lloyd, Robert Lawton Eoff Chemical research in toxicology 2013 topics set
Evolving uses of oral reverse transcriptase inhibitors in the HIV-1 epidemic: from treatment to prevention. Ravindra K Gupta, DA Van de Vijver, S Manicklal, MA Wainberg Retrovirology 2013 pols set
C-terminal extension of the yeast mitochondrial DNA polymerase determines the balance between synthesis and degradation. Katrin Viikov, Olga Jasnovidova, Tiina Tamm, Juhan Sedman PloS one 2012 partial results
DNA expansions generated by human Polμ on iterative sequences. Ana Aza, Maria Jose Martin, Raquel Juarez, Luis Blanco, Gloria Terrados Nucleic acids research 2012 new
Spatiotemporal recruitment of human DNA polymerase delta to sites of UV damage. Jennifer Chea, Sufang Zhang, Hong Zhao, Zhongtao Zhang, Ernest Y C Lee, Zbigniew Darzynkiewicz, Marietta Y W T Lee Cell cycle (Georgetown, Tex.) 2012 pols set
DNA polymerization-independent functions of DNA polymerase epsilon in assembly and progression of the replisome in fission yeast. Tetsuya Handa, Mai Kanke, Tatsuro S Takahashi, Takuro Nakagawa, Hisao Masukata Molecular biology of the cell 2012 new
New Nitrogen Containing Substituents at the Indole-2-carboxamide Yield High Potent and Broad Spectrum Indolylarylsulfone HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors. Giuseppe La Regina, Antonio Coluccia, Andrea Brancale, Francesco Piscitelli, Valeria Famiglini, Sandro Cosconati, Giovanni Maga, Alberta Samuele, Emmanuel Gonzales, B Clotet, Dominique Schols, Jose Este, Ettore Novellino, Romano Silvestri Journal of medicinal chemistry 2012 pols set
In vivo antitumor effect of liposomes with sialyl Lewis X including monogalactosyl diacylglycerol, a replicative DNA polymerase inhibitor, from spinach. Yoshiyuki Mizushina, Takahiko Hada, Hiromi Yoshida Oncology reports 2012 topics set
Preferred WMSA catalytic mechanism of the nucleotidyl transfer reaction in human DNA polymerase κ elucidates error-free bypass of a bulky DNA lesion. Lee Lior-Hoffmann, Liming Wang, Shenglong Wang, Nicholas E Geacintov, Suse Broyde, Yongqing Zhang Nucleic acids research 2012 new
Overexpression of the mTERT gene by adenoviral vectors promotes the proliferation of neuronal stem cells in vitro and stimulates neurogenesis in the hippocampus of mice. Mengying Liu, Yao Hu, Lijuan Zhu, Chen Chen, Yongqing Zhang, Weixiang Sun, Qigang Zhou Journal of biomedical research 2012 pols set
A comprehensive strategy to discover inhibitors of the translesion synthesis DNA polymerase κ. Kinrin Yamanaka, Dorjbal Dorjsuren, Robert Lawton Eoff, Martin Egli, David J Maloney, Ajit Jadhav, Anton Simeonov, R Stephen Lloyd PloS one 2012 topics set
The role of the PHP domain associated with DNA polymerase X from Thermus thermophilus HB8 in base excision repair. Shuhei Nakane, Noriko Nakagawa, Seiki Kuramitsu, Ryoji Masui DNA repair 2012 topics set
Characterization and PCR application of a new high-fidelity DNA polymerase from Thermococcus waiotapuensis. Sung Suk Cho, Kee Pum Kim, Kang Keun Lee, Man-Hui Youn, Suk-Tae Kwon Enzyme and microbial technology 2012 topics set
Perspective: pre-chemistry conformational changes in DNA polymerase mechanisms. Tamar Schlick, Karunesh Arora, William A Beard, Samuel H Wilson Theoretical chemistry accounts 2012 new
Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65. Mahavir Singh, Zhonghua Wang, Bon-Kyung Koo, Anooj Patel, Duilio Cascio, Kathleen Collins, Juli Feigon Molecular cell 2012 topics set
Temperature dependence of accuracy of DNA polymerase I from Geobacillus anatolicus. Melike Cağlayan, Neş'e Bilgin Biochimie 2012 topics set
Characterization of human DNA polymerase κ promoter in response to benzo[a]pyrene diol epoxide. Huifang Zhu, Yanfeng Fan, Jing Shen, Hongyan Qi, Jimin Shao Environmental toxicology and pharmacology 2012 topics set
A nucleotide analogue induced gain of function corrects the error-prone nature of human DNA polymerase iota. Amit Ketkar, Maroof Khan Zafar, Surajit Banerjee, Victor E Marquez, Martin Egli, Robert Lawton Eoff Journal of the American Chemical Society 2012 topics set
I-PfoP3I: a novel nicking HNH homing endonuclease encoded in the group I intron of the DNA polymerase gene in Phormidium foveolarum phage Pf-WMP3. Shuanglei Kong, Xinyao Liu, Liwen Fu, Xiangchun Yu, Chengcai An PloS one 2012 new
GCN5 protects vertebrate cells against UV-irradiation via controlling gene expression of DNA polymerase η. Hidehiko Kikuchi, Futoshi Kuribayashi, Shinobu Imajoh-Ohmi, Hideki Nishitoh, Yasunari Takami, Tatsuo Nakayama The Journal of biological chemistry 2012 new
Simple and efficient purification of Escherichia coli DNA polymerase V: Cofactor requirements for optimal activity and processivity in vitro. Kiyonobu Karata, Alexandra Vaisman, Myron F Goodman, Roger Woodgate DNA repair 2012 topics set
Single-molecule microscopy reveals new insights into nucleotide selection by DNA polymerase I. RP Markiewicz, KB Vrtis, David Rueda, Louis J Romano Nucleic acids research 2012 topics set
Improved gap repair cloning in yeast: treatment of the gapped vector with Taq DNA polymerase avoids vector self-ligation. Daniela Bessa, Filipa Pereira, Roxana Moreira, Björn Johansson, Odília Queirós Yeast (Chichester, England) 2012 pols set
Association between newly identified variant form of DNA polymerase beta (Δ 208-304) and ovarian cancer. Kalyani Khanra, Kakali Panda, Chandan Bhattacharya, Ak Mitra, Ranu Sarkar, Sanjeev Banerjee, Nandan Bhattacharyya Cancer biomarkers : section A of Disease markers 2012 topics set
Identification of an Unfolding Intermediate for a DNA Lesion Bypass Polymerase. Shanen M Sherrer, Brian A Maxwell, Lindsey R Pack, Kevin A Fiala, Jason D Fowler, Jun Zhang, Zucai Suo Chemical research in toxicology 2012 topics set
Label-free electrical detection of pyrophosphate generated from DNA polymerase reactions on field-effect devices. Grace M Credo, Xing Su, Kai Wu, Oguz H Elibol, David J Liu, Bobby Reddy, Ta-Wei Tsai, Brian R Dorvel, Jonathan S Daniels, Rashid Bashir, Madoo Varma The Analyst 2012 new
Enhancement of human DNA polymerase η activity and fidelity is dependent upon a bipartite interaction with the Werner syndrome protein. Leena Maddukuri, Amit Ketkar, Sarah Eddy, Maroof Khan Zafar, Wezley C Griffin, Robert Lawton Eoff The Journal of biological chemistry 2012 new
Unfavorable electrostatic and steric interactions in DNA polymerase β E295K mutant interfere with the enzyme's pathway. Yingqian Li, Chelsea L Gridley, Joachim Jaeger, Joann B Sweasy, Tamar Schlick Journal of the American Chemical Society 2012 topics set
Measuring cation dependent DNA polymerase fidelity landscapes by deep sequencing. Bradley Michael Zamft, Adam H Marblestone, Konrad Kording, Daniel Schmidt, Daniel Martin-Alarcon, Keith Tyo, Edward S Boyden, George Church PloS one 2012 new
Interferon regulatory factor 1 transactivates expression of human DNA polymerase η in response to carcinogen N-methyl-N'-nitro-N-nitrosoguanidine. Hongyan Qi, Huifang Zhu, Meng Lou, Yanfeng Fan, Hong Liu, Jing Shen, Zhongjie Li, Xue Lv, Jianzhen Shan, Lijun Zhu, Y Eugene Chin, Jimin Shao The Journal of biological chemistry 2012 new
The human lagging strand DNA polymerase δ holoenzyme is distributive. Zhenxin Hu, Senthil K Perumal, Hongjun Yue, Stephen J Benkovic The Journal of biological chemistry 2012 topics set
The interplay of DNA polymerase λ in diverse DNA damage repair pathways in higher plant genome in response to environmental and genotoxic stress factors. Sujit Roy, Swarup Roy Choudhury, Kalipada Das Plant signaling & behavior 2012 new
Contribution of Partial Charge Interactions and Base-Stacking to the Efficiency of Primer-Extension at and beyond Abasic Sites in DNA. Shuangluo Xia, Ashwani Kumar Vashishtha, David Bulkley, Soo Hyun Eom, Jianhong Wang, William H Konigsberg Biochemistry 2012 topics set
The E288K Colon Tumor Variant of DNA Polymerase Beta Is a Sequence Specific Mutator. Drew L Murphy, Katherine A Donigan, Joachim Jaeger, Joann B Sweasy Biochemistry 2012 topics set
Telmisartan directly ameliorates the neuronal inflammatory response to IL-1beta partly through the JNK/c-Jun and NADPH oxidase pathways. Tao Pang, Juan Wang, Julius Benicky, Enrique Sanchez-Lemus, Juan M Saavedra Journal of neuroinflammation 2012 new
Selection and characterization of Autographa californica multiple nucleopolyhedrovirus DNA polymerase mutations. Guozhong Feng, David K Thumbi, Jondavid de Jong, Jeffrey J Hodgson, Basil M Arif, Daniel Doucet, Peter J Krell Journal of virology 2012 new
Mitochondrial alteration in malignantly transformed human small airway epithelial cells induced by alpha particles. Suping Zhang, Gengyun Wen, Sarah Xl Huang, Jianrong Wang, Jian Tong, Tom K Hei International journal of cancer. Journal international du cancer 2012 new
Rapid incorporation kinetics and improved fidelity of a novel class of 3'-OH unblocked reversible terminators. Andrew F Gardner, Jinchun Wang, Weidong Wu, Jennifer Karouby, Hong Li, Brian P Stupi, William E Jack, Megan N Hersh, Michael L Metzker Nucleic acids research 2012 topics set
Using a Fluorescent Cytosine Analogue tC(o) To Probe the Effect of the Y567 to Ala Substitution on the Preinsertion Steps of dNMP Incorporation by RB69 DNA Polymerase. Shuangluo Xia, Jeff W Beckman, Jianhong Wang, William H Konigsberg Biochemistry 2012 pols set
Strategies for the design of HIV-1 non-nucleoside reverse transcriptase inhibitors: lessons from the development of seven representative paradigms. Dongyue Li, Peng Zhan, Erik De Clercq, Xinyong Liu Journal of medicinal chemistry 2012 pols set
The C-terminus of Dpb2 is required for interaction with Pol2 and for cell viability. Isabelle Isoz, Ulf Persson, Kirill Volkov, Erik Johansson Nucleic acids research 2012 pols set
Transient expression and activity of human DNA polymerase iota in loach embryos. Irina V Makarova, Andrey A Kazakov, Alena V Makarova, Nella V Khaidarova, Larisa V Kozikova, Valentina V Nenasheva, Leonid V Gening, Vyacheslav Z Tarantul, Ludmila E Andreeva Biotechnology letters 2012 pols set
DNA polymerase eta is targeted by Mdm2 for polyubiquitination and proteasomal degradation in response to ultraviolet irradiation. Yong-Sam Jung, Yingjuan Qian, Xinbin Chen DNA repair 2012 topics set
The structural basis of the kinetic mechanism of a gap-filling X-family DNA polymerase that binds Mg(2+)-dNTP before binding to DNA. Shuhei Nakane, Hirohito Ishikawa, Noriko Nakagawa, Seiki Kuramitsu, Ryoji Masui Journal of molecular biology 2012 partial results
Inhibition of Taq DNA polymerase by iridoid aglycone derivates. Carlos Rodolfo Pungitore, Celina García, V Sotero Martín, Carlos E Tonn Cellular and molecular biology (Noisy-le-Grand, France) 2012 pols set
Mitochondrial DNA copy number is regulated in a tissue specific manner by DNA methylation of the nuclear-encoded DNA polymerase gamma A. Richard D W Kelly, Arsalan Mahmud, Matthew McKenzie, Ian A Trounce, Justin C St John Nucleic acids research 2012 new
Structure of monoubiquitinated PCNA: Implications for DNA polymerase switching and Okazaki fragment maturation. Zhenzhong Zhang, Sufang Zhang, Szu Hua Sharon Lin, Xiaoxiao Wang, Licheng Wu, Ernest Y C Lee, Marietta Y W T Lee Cell cycle (Georgetown, Tex.) 2012 complete Zhenzhong Zhang*
Transmitted antiretroviral drug resistance and thumb subdomain polymorphisms among newly HIV-1 diagnosed patients infected with CRF01_AE and CRF07_BC virus in Guangdong Province, China. Changfu Yang, Shuyuan Liu, Taisong Zhang, Yaping Hou, Xiaoli Liu, Yun Gao, Guang Yang, Zhen Wang, Huayun Chen, Ming Li, Zhenyu Zhu AIDS research and human retroviruses 2012 topics set
Homologous recombination mediates S-phase-dependent radioresistance in cells deficient in DNA polymerase eta. Nils H Nicolay, Rebecca Carter, Stephanie B Hatch, Niklas Schultz, Remko Prevo, W Gillies McKenna, Thomas Helleday, Ricky A Sharma Carcinogenesis 2012 topics set
Mechanism of taq DNA polymerase inhibition by fullerene derivatives: insight from computer simulations. Praveen Nedumpully Govindan, Luca Monticelli, Emppu Salonen The journal of physical chemistry. B 2012 pols set
REV1 and DNA polymerase zeta in DNA interstrand crosslink repair. S Sharma, CE Canman Environmental and molecular mutagenesis 2012 new
Establishment and evaluation of a stable steroidogenic caprine luteal cell line. Wei Li, Xingang Xu, Yong Huang, Zhongjie Li, Gaoshui Yu, Zhisheng Wang, Li Ding, Dewen Tong Theriogenology 2012 new
Regulation of the specialized DNA polymerase eta: revisiting the biological relevance of its PCNA- and ubiquitin-binding motifs. Emmanuelle Despras, Noémie Delrieu, Charlène Garandeau, Sana Ahmed-Seghir, Patricia L Kannouche Environmental and molecular mutagenesis 2012 new
Altered Ig Hypermutation Pattern and Frequency in Complementary Mouse Models of DNA Polymerase ζ Activity. Janssen Daly, Katarzyna Bebenek, Danielle L Watt, Kathleen Richter, Chuancang Jiang, Ming-Lang Zhao, Madhumita Ray, William Glenn McGregor, Thomas A Kunkel, Marilyn Diaz Journal of immunology (Baltimore, Md. : 1950) 2012 topics set
Molecular recognition of canonical and deaminated bases by P. abyssi family B DNA polymerase. Jérôme Gouge, Céline Ralec, Ghislaine Henneke, Marc Delarue Journal of molecular biology 2012 complete Jerome Gouge*
KlenTaq DNA polymerase adopts unique recognition states when encountering matched, mismatched, and abasic template sites: an NMR study. Bastian Holzberger, M Gabriele Pszolla, Andreas Marx, Heiko M Möller Chembiochem : a European journal of chemical biology 2012 new
Diagnosis of brugian filariasis by loop-mediated isothermal amplification. Catherine B Poole, Nathan A Tanner, Yongqing Zhang, Thomas C Evans, Clotilde K S Carlow PLoS neglected tropical diseases 2012 complete Catherine B Poole*
Model of elongation of short DNA sequence by thermophilic DNA polymerase under isothermal conditions. Tomohiro Kato, Xingguo Liang, Hiroyuki Asanuma Biochemistry 2012 complete Xingguo Liang*
The Human POLB Gene is Mutated in a High Percentage of Colorectal Tumors. Katherine A Donigan, Ka-Wai Sun, Antonia A Nemec, Drew L Murphy, Xiangyu Cong, Veronika Northrup, Daniel Zelterman, Joann B Sweasy The Journal of biological chemistry 2012 topics set
Deep sequencing of the Hepatitis B Virus in Hepatocellular Carcinoma patients reveals enriched integration events, structural alterations and sequence variations. Soo Ting Toh, Yu Jin, Lizhen Liu, Jingbo Wang, Farbod Babrzadeh, Baback Gharizadeh, Mostafa Ronaghi, Han Chong Toh, Pierce Kah-Hoe Chow, Alexander Y-F Chung, London Lucien P-J Ooi, Caroline G Lee Carcinogenesis 2012 new
Design, synthesis, anti-HIV evaluation and molecular modeling of piperidine-linked amino-triazine derivatives as potent non-nucleoside reverse transcriptase inhibitors. Xuwang Chen, Peng Zhan, Xin Liu, Ziheng Cheng, Caicai Meng, Siyuan Shao, Christophe Pannecouque, Erik De Clercq, Xinyong Liu Bioorganic & medicinal chemistry 2012 pols set
[Purification of Taq DNA polymerase expressed in Escherichia coli]. Tian-Lei Liu, Shou-Bin Xue, Fang Wang, Lin-Ying Zhu, Wei-Wei Liang, Sheng-Xuan Qu, Wen-Bo Cai Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji 2012 pols set
Long-term cultivation of human corneal endothelial cells by telomerase expression. Zhiping Liu, Jing Zhuang, Chaoyang Li, Pengxia Wan, Naiyang Li, Qiang Zhou, Chenjing Zhou, Zheqian Huang, Zhichong Wang Experimental eye research 2012 topics set
Gene 5.5 protein of bacteriophage T7 in complex with Escherichia coli nucleoid protein H-NS and transfer RNA masks transfer RNA priming in T7 DNA replication. B Zhu, Seung-Joo Lee, Min Tan, En-Duo Wang, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 2012 new
Proofreading of ribonucleotides inserted into DNA by yeast DNA polymerase ɛ Jessica S Williams, Anders R Clausen, Stephanie A Nick McElhinny, Brian E Watts, Erik Johansson, Thomas A Kunkel DNA repair 2012 topics set
Discovery of novel 2-(3-(2-chlorophenyl)pyrazin-2-ylthio)-N-arylacetamides as potent HIV-1 inhibitors using a structure-based bioisosterism approach. Peng Zhan, Wenmin Chen, Zhongjie Li, Xincang Li, Xuwang Chen, Ye Tian, Christophe Pannecouque, Erik De Clercq, Xinyong Liu Bioorganic & medicinal chemistry 2012 pols set
Synthesis, biological evaluation and molecular modeling of 4,6-diarylpyrimidines and diarylbenzenes as novel non-nucleosides HIV-1 reverse transcriptase inhibitors. Sergio R Ribone, Volker Leen, Marcela Madrid, Wim Dehaen, Dirk Daelemans, Christophe Pannecouque, Margarita C Briñón European journal of medicinal chemistry 2012 pols set
Effect of translocation defective reverse transcriptase inhibitors on the activity of n348i, a connection subdomain drug resistant hiv-1 reverse transcriptase mutant. Eleftherios Michailidis, Kamlendra Singh, Emily M Ryan, Atsuko Hachiya, Yee Tsuey Ong, Karen A Kirby, Bruno Marchand, Eiichi N Kodama, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos Cellular and molecular biology (Noisy-le-Grand, France) 2012 pols set
J. Biol. Chem. 2012 topics set
A short adaptive path from DNA to RNA polymerases. Christopher Cozens, Vitor B Pinheiro, Alexandra Vaisman, Roger Woodgate, Philipp Holliger Proceedings of the National Academy of Sciences of the United States of America 2012 topics set
Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy. Ajay Ummat, Olga Rechkoblit, Rinku Jain, Jayati Roy Choudhury, Robert E Johnson, Timothy D Silverstein, Angeliki Buku, Samer Lone, Louise Prakash, Satya Prakash, Aneel K Aggarwal Nature structural & molecular biology 2012 topics set
Development of a polymerase chain reaction for the detection of abalone herpesvirus infection based on the DNA polymerase gene. M H Chen, S T Kuo, T Renault, C S Friedman, P H Chang Journal of virological methods 2012 new
Kinetics and fidelity of polymerization by DNA polymerase III from Sulfolobus solfataricus. Robert J Bauer, Michael T Begley, Michael A Trakselis Biochemistry 2012 new
DNA stabilization at the Bacillus subtilis PolX core--a binding model to coordinate polymerase, AP-endonuclease and 3'-5' exonuclease activities. Benito Baños, Laurentino Villar, Margarita Salas, Miguel de Vega Nucleic acids research 2012 topics set
Inhibitory effects of glycyrrhetinic Acid on DNA polymerase and inflammatory activities. Tsukasa Ishida, Yoshiyuki Mizushina, Saori Yagi, Yasuhiro Irino, Shin Nishiumi, Ikuya Miki, Yasuyuki Kondo, Shigeto Mizuno, Hiromi Yoshida, Takeshi Azuma, Masaru Yoshida Evidence-based complementary and alternative medicine : eCAM 2012 new
Watching DNA polymerase η make a phosphodiester bond. Teruya Nakamura, Yaofeng Zhao, Yuriko Yamagata, Yue-Jin Hua, Wei Wen Yang Nature 2012 new
A novel POLG gene mutation in a patient with SANDO. Bulent Kurt, Ali B Naini, William C Copeland, Jiesheng Lu, Salvatore DiMauro, Michio Hirano Journal of experimental and integrative medicine 2012 new
Overexpression of DNA polymerase zeta reduces the mitochondrial mutability caused by pathological mutations in DNA polymerase gamma in yeast. Enrico Baruffini, Fausta Serafini, Iliana Ferrero, Tiziana Lodi PloS one 2012 new
Arylazolylthioacetanilide. Part 11: Design, Synthesis and Biological Evaluation of 1,2,4-Triazole Thioacetanilide Derivatives as Novel Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors. Zhongjie Li, Yuan Cao, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu Medicinal chemistry (Shāriqah (United Arab Emirates)) 2012 pols set
Active DNA unwinding dynamics during processive DNA replication. José A Morin, Francisco J Cao, José María Lázaro, J Ricardo Arias-Gonzalez, José M Valpuesta, José L Carrascosa, Margarita Salas, Borja Ibarra Proceedings of the National Academy of Sciences of the United States of America 2012 pols set
Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. Dong Ding, Xiaoyan Lou, Dasong Hua, Wei Yu, Lisha Li, Jun Wang, Feng Gao, Na Zhao, Guoping Ren, Lanjuan Li, Biaoyang Lin PLoS genetics 2012 new
Bidendate and tridendate metal-ion coordination states within ternary complexes of RB69 DNA polymerase. Shuangluo Xia, Soo Hyun Eom, William H Konigsberg, Jianhong Wang Protein science : a publication of the Protein Society 2012 topics set
Mechanisms Employed by Escherichia coli to Prevent Ribonucleotide Incorporation into Genomic DNA by Pol V. John P McDonald, Alexandra Vaisman, Wojciech Kuban, Myron F Goodman, Roger Woodgate PLoS genetics 2012 new
An Interaction between DNA Polymerase and Helicase is Essential for the High Processivity of the Bacteriophage T7 Replisome. Arkadiusz W Kulczyk, Barak Akabayov, Seung-Joo Lee, Mihnea Bostina, Steven A Berkowitz, Charles C Richardson The Journal of biological chemistry 2012 partial results
Computational prediction of residues involved in fidelity checking for DNA synthesis in DNA polymerase I. Sarah E Graham, FatimaSultana Syeda, G Andrés Cisneros Biochemistry 2012 complete G Andrés Cisneros*
Structural basis of the allosteric inhibitor interaction on the HIV-1 reverse transcriptase RNase H domain. Martin T Christen, Lakshmi Menon, Nataliya S Myshakina, Jinwoo Ahn, Michael A. Parniak, Rieko Ishima Chemical biology & drug design 2012 pols set
Evidence for Abasic Site Sugar Phosphate-Mediated Cytotoxicity in Alkylating Agent Treated Saccharomyces cerevisiae. Michelle L Heacock, Vladimir P Poltoratsky, Rajendra Prasad, Samuel H Wilson PloS one 2012 new
HIV-1 Reverse Transcription. Wei-Shau Hu, Stephen H Hughes Cold Spring Harbor perspectives in medicine 2012 topics set
In-vitro replication studies on o(2)-methylthymidine and o(4)-methylthymidine. Nisana Andersen, Jianshuang Wang, Pengcheng Wang, Yanan Jiang, Yinsheng Wang Chemical research in toxicology 2012 new
Mouse models of DNA polymerases. Miriam Rose Menezes, Joann B Sweasy Environmental and molecular mutagenesis 2012 topics set
DNA polymerase eta participates in the mutagenic bypass of adducts induced by benzo[a]pyrene diol epoxide in mammalian cells. Alden C Klarer, L Jay Stallons, Tom J Burke, Robert L Skaggs, W Glenn McGregor PloS one 2012 topics set
Molecular interactions in the priming complex of bacteriophage T7. Arkadiusz W Kulczyk, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 2012 topics set
Effect of silencing PARG in human colon carcinoma LoVo cells on the ability of HUVEC migration and proliferation. J Pan, N J S Fauzee, Y-l Wang, Y-T Sheng, Y Tang, J-Q Wang, W-q Wu, J-x Yan, J Xu Cancer gene therapy 2012 new
Dynamic localization of Trypanosoma brucei mitochondrial DNA polymerase ID. Jeniffer Concepción-Acevedo, Juemin Luo, Michele M Klingbeil Eukaryotic cell 2012 pols set
A germline polymorphism of DNA polymerase Beta induces genomic instability and cellular transformation. Jennifer Yamtich, Antonia A Nemec, Agnes Keh, Joann B Sweasy PLoS genetics 2012 new
Age-dependent down-regulation of DNA polymerase δ1 in human lymphocytes. Jin-Ling Wang, Hong-Lin Guo, Pei-Chang Wang, Chen-Geng Liu Molecular and cellular biochemistry 2012 new
Subtractive genomics approach to identify putative drug targets and identification of drug-like molecules for beta subunit of DNA polymerase III in Streptococcus species. John J Georrge, V V Umrania Applied biochemistry and biotechnology 2012 topics set
Stalled Polη at its cognate substrate initiates an alternative translesion synthesis pathway via interaction with REV1. Wakana Ito, Masayuki Yokoi, Nobutaka Sakayoshi, Yasutaka Sakurai, Jun-Ichi Akagi, Hiroshi Mitani, Fumio Hanaoka Genes to cells : devoted to molecular & cellular mechanisms 2012 new
Structures of KlenTaq DNA polymerase caught while incorporating C5-modified pyrimidine and C7-modified 7-deazapurine nucleoside triphosphates. Konrad Bergen, Anna-Lena Steck, Stefan Strütt, Anna Baccaro, Wolfram Welte, Kay Diederichs, Andreas Marx Journal of the American Chemical Society 2012 topics set
Differential requirement for the N-terminal catalytic domain of the DNA polymerase ε p255 subunit in the mitotic cell cycle and the endocycle. Osamu Suyari, Mieko Kawai, Hiroyuki Ida, Hideki Yoshida, Kengo Sakaguchi, Masamitsu Yamaguchi Gene 2012 new
Structural basis of recruitment of DNA polymerase ζ by interaction between REV1 and REV7 proteins. Sotaro Kikuchi, Kodai Hara, Toshiyuki Shimizu, Mamoru Sato, Hiroshi Hashimoto The Journal of biological chemistry 2012 topics set
A conserved motif in the C-terminal tail of DNA polymerase α tethers primase to the eukaryotic replisome. Mairi L Kilkenny, Giacomo De Piccoli, Rajika L Perera, Karim Labib, Luca Pellegrini The Journal of biological chemistry 2012 new
Recent advances in the research of 2,3-diaryl-1,3-thiazolidin-4-one derivatives as potent HIV-1 non-nucleoside reverse transcriptase inhibitors. Ye Tian, Peng Zhan, Diwakar Rai, Jiyan Zhang, Erik De Clercq, Xinyong Liu Current medicinal chemistry 2012 pols set
Thermostable DNA polymerase from a viral metagenome is a potent RT-PCR enzyme. Michael J Moser, Robert A DiFrancesco, Krishne Gowda, Audrey J Klingele, Darby R Sugar, Stacy Stocki, David A Mead, Thomas W Schoenfeld PloS one 2012 new
DNA replication fidelity in Escherichia coli: a multi-DNA polymerase affair. Iwona J Fijalkowska, Roel M Schaaper, Piotr Jonczyk FEMS microbiology reviews 2012 new
Differential Furanose Selection in the Active Sites of Archaeal DNA Polymerases Probed by Fixed-Conformation Nucleotide Analogues. Amit Ketkar, Maroof Khan Zafar, Surajit Banerjee, Victor E Marquez, Martin Egli, Robert Lawton Eoff Biochemistry 2012 topics set
Human DNA Polymerase {epsilon} Is Able to Efficiently Extend from Multiple Consecutive Ribonucleotides. A Yasemin Goksenin, Walter J Zahurancik, Kimberly G Lecompte, DJ Taggart, Zucai Suo, Zachary F Pursell The Journal of biological chemistry 2012 new
Genomic amplification of the human telomerase gene (hTERC) associated with human papillomavirus is related to the progression of uterine cervical dysplasia to invasive cancer. Hongqian Liu, Shanling Liu, He Wang, Xiaoyan Xie, Xinlian Chen, Xuemei Zhang, Yongqing Zhang Diagnostic pathology 2012 new
Influence of usnic acid and its derivatives on the activity of mammalian poly(ADP-ribose)polymerase 1 and DNA polymerase β. Alexandra Zakharenko, Dmitry Sokolov, Olga Luzina, Maria V Sukhanova, Svetlana N Khodyreva, Olga Zakharova, Nariman Salakhutdinov, Olga I Lavrik Medicinal chemistry (Shāriqah (United Arab Emirates)) 2012 new
A four-subunit DNA polymerase ζ complex containing Pol δ accessory subunits is essential for PCNA-mediated mutagenesis. Alena V Makarova, Joseph L Stodola, Peter M J Burgers Nucleic acids research 2012 new
DNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesion. Bret D Freudenthal, William A Beard, Samuel H Wilson Nucleic acids research 2012 new
Structural and Inhibition Studies of the RNase H Function of Xenotropic Murine Leukemia Virus-Related Virus Reverse Transcriptase. Karen A Kirby, Bruno Marchand, Yee Tsuey Ong, Tanyaradzwa P Ndongwe, Atsuko Hachiya, Eleftherios Michailidis, Maxwell D Leslie, Daniel V Sietsema, Tracy L Fetterly, Christopher A Dorst, Kamalendra Singh, Zhengqiang Wang, Michael A. Parniak, Stefan G Sarafianos Antimicrobial agents and chemotherapy 2012 pols set
The essential role of the 3' terminal template base in the first steps of protein-primed DNA replication. Irene Rodríguez, Elisa Longás, Miguel de Vega, Margarita Salas PloS one 2012 new
HIV-1 reverse transcriptase complex with DNA and nevirapine reveals non-nucleoside inhibition mechanism. Kalyan Das, Sergio E Martinez, Joseph David Bauman, Edward Arnold Nature structural & molecular biology 2012 topics set
My life with bacteriophage O29. Margarita Salas The Journal of biological chemistry 2012 new
Mutagenic bypass of 8-oxo-7,8-dihydroguanine (8-hydroxyguanine) by DNA polymerase κ in human cells. Hiroyuki Kamiya, Masahiro Kurokawa Chemical research in toxicology 2012 new
Human DNA polymerase β, but not λ, can bypass a 2-deoxyribonolactone lesion together with proliferating cell nuclear antigen. Emmanuele Crespan, Emanuela Pasi, Shuhei Imoto, Ulrich Hübscher, Marc M Greenberg, Giovanni Maga ACS chemical biology 2012 new
Simultaneous multiple target detection in real-time loop-mediated isothermal amplification. Nathan A Tanner, Yongqing Zhang, Thomas C Evans BioTechniques 2012 new
Silencing of human DNA polymerase λ causes replication stress and is synthetically lethal with an impaired S phase checkpoint. Elisa Zucca, Federica Bertoletti, Ursula Wimmer, Elena Ferrari, Giuliano Mazzini, Svetlana V Khoronenkova, Nicole Grosse, Barbara van Loon, Grigory L Dianov, Ulrich Hübscher, Giovanni Maga Nucleic acids research 2012 new
DNA polymerase delta in dna replication and genome maintenance. Marc J Prindle, Lawrence A Loeb Environmental and molecular mutagenesis 2012 new
Segregation of replicative DNA polymerases during S phase: DNA polymerase ε, but not DNA polymerases α/δ, are associated with lamins throughout S phase in human cells. Markku Vaara, Harri Itkonen, Tomi Hillukkala, Zhe Liu, Heinz Peter Nasheuer, Daniel Schaarschmidt, Helmut Pospiech, Juhani E Syväoja The Journal of biological chemistry 2012 topics set
Defect of Dpb2p, a noncatalytic subunit of DNA polymerase ɛ, promotes error prone replication of undamaged chromosomal DNA in Saccharomyces cerevisiae. Joanna Kraszewska, Marta Garbacz, Piotr Jonczyk, Iwona J Fijalkowska, Malgorzata Jaszczur Mutation research 2012 topics set
Human telomerase reverse transcriptase (hTERT) is a novel target of the Wnt/β-catenin pathway in human cancer. Yongqing Zhang, LingLing Toh, Peishan Lau, Xueying Wang The Journal of biological chemistry 2012 new
Maraviroc and other HIV-1 entry inhibitors exhibit a class-specific redistribution effect that results in increased extracellular viral load. Victor G Kramer, Susan M Schader, Maureen Oliveira, Susan P Colby-Germinario, Daniel A Donahue, Diane N Singhroy, Randy Tressler, Richard D Sloan, Mark A. Wainberg Antimicrobial agents and chemotherapy 2012 pols set
Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase δ for degradation in response to DNA damage. Sufang Zhang, Yajing Zhou, Ali Sarkeshik, John Yates, Timothy M Thomson, Zhongtao Zhang, Ernest Y C Lee, Marietta Y W T Lee The Journal of biological chemistry 2012 topics set
Recent progress in small molecule CCR5 antagonists as potential HIV-1 entry inhibitors. Wenwen Chen, Peng Zhan, Erik De Clercq, Xinyong Liu Current pharmaceutical design 2012 pols set
Effect of β,γ-CHF- and β,γ-CHCl-dGTP Halogen Atom Stereochemistry on the Transition State of DNA Polymerase β Keriann Oertell, Yue Wu, Valeria M Zakharova, Boris A Kashemirov, David D Shock, William A Beard, Samuel H Wilson, Charles E McKenna, Myron F Goodman Biochemistry 2012 new
Interaction between Escherichia coli DNA polymerase IV and single-stranded DNA-binding protein is required for DNA synthesis on SSB-coated DNA. Asako Furukohri, Yoshito Nishikawa, Masahiro Tatsumi Akiyama, Hisaji Maki Nucleic acids research 2012 pols set
Microbiological safety of a novel bio-artificial liver support system based on porcine hepatocytes: a experimental study. Bing Han, Xiao-Lei Shi, Yongqing Zhang, Xue-Hui Chu, Jin-Yang Gu, Jiang-Qiang Xiao, Hao-Zhen Ren, Jia-Jun Tan, Zhong-Ze Gu, Yi-Tao Ding European journal of medical research 2012 new
Factors influencing the transfer of porcine endogenous retroviruses across the membrane in bioartificial livers. Xiao-Lei Shi, Bing Han, Jia-Jun Tan, Xianwen Yuan, Yongqing Zhang, Jiang-Qiang Xiao, Zhong-Ze Gu, Yi-Tao Ding The International journal of artificial organs 2012 new
Single-molecule Förster resonance energy transfer reveals an innate fidelity checkpoint in DNA polymerase I. Svitlana Y Berezhna, JP Gill, Rajan Lamichhane, David P Millar Journal of the American Chemical Society 2012 pols set
Efficient derivation and genetic modifications of human pluripotent stem cells on engineered human feeder cell lines. Chunlin Zou, Bin-Kuan Chou, Sarah N Dowey, Kitman Tsang, Xiaosong Huang, Cyndi F Liu, Cory Smith, Jonathan Yen, Prashant Mali, Yu Alex Zhang, Linzhao Cheng, Zhaohui Ye Stem cells and development 2012 new
E2F1: a potential negative regulator of hTERT transcription in normal cells upon activation of oncogenic c-Myc. Yongqing Zhang, Ling Chen, Shiming Yang, Dianchun Fang Medical science monitor : international medical journal of experimental and clinical research 2012 new
Hyperactivation of PARP Triggers Nonhomologous End-Joining in Repair-Deficient Mouse Fibroblasts. Natalie R Gassman, Donna F Stefanick, Padmini S Kedar, Julie K Horton, Samuel H Wilson PloS one 2012 new
Mismatch repair balances leading and lagging strand DNA replication fidelity. Scott A Lujan, Jessica S Williams, Zachary F Pursell, Amy A Abdulovic-Cui, Alan B Clark, Stephanie A Nick McElhinny, Thomas A Kunkel PLoS genetics 2012 new
Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides. Weina Wang, Eugene Y Wu, Homme W Hellinga, Lorena S Beese The Journal of biological chemistry 2012 new
A comparison of the ability of rilpivirine (TMC278) and selected analogues to inhibit clinically relevant HIV-1 reverse transcriptase mutants. Barry C Johnson, Gary T Pauly, Ganesha Rai, Disha Patel, Joseph David Bauman, Heather L Baker, Kalyan Das, Joel P Schneider, David J Maloney, Edward Arnold, Craig J Thomas, Stephen H Hughes Retrovirology 2012 pols set
RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity. Deborah L Croteau, Marie L Rossi, Chandrika Canugovi, Jane Tian, Peter Sykora, Mahesh Ramamoorthy, Zhengming Wang, Dharmendra Kumar Singh, Mansour Akbari, Rajesh Kasiviswanathan, William C Copeland, Vilhelm A Bohr Aging cell 2012 topics set
The Werner syndrome exonuclease facilitates DNA degradation and high fidelity DNA polymerization by human DNA polymerase δ Ashwini S Kamath-Loeb, Jiang-Cheng Shen, Michael W Schmitt, Lawrence A Loeb The Journal of biological chemistry 2012 topics set
[Establishment of human cardiac C protein induced experimental autoimmune myocarditis model in rat]. Li-na Han, Tie-ling Li, Guo-lei Ding, Jian-wei Liu, Yu Ding, Ya-jing Zhang Zhonghua xin xue guan bing za zhi 2012 new
Regulation of human DNA polymerase delta in the cellular responses to DNA damage. Marietta Y W T Lee, Sufang Zhang, Szu Hua Sharon Lin, Jennifer Chea, Xiaoxiao Wang, Christine Leroy, Agnes Wong, Zhongtao Zhang, Ernest Y C Lee Environmental and molecular mutagenesis 2012 pols set
The human gastric cancer-associated DNA polymerase β variant D160N is a mutator that induces cellular transformation. Katherine A Donigan, Suzanne E Hile, Kristin A Eckert, Joann B Sweasy DNA repair 2012 topics set
Evaluation of a novel hybrid bioartificial liver based on a multi-layer flat-plate bioreactor. Xiao-Lei Shi, Yongqing Zhang, Xue-Hui Chu, Bing Han, Jin-Yang Gu, Jiang-Qiang Xiao, Jia-Jun Tan, Zhong-Ze Gu, Hao-Zhen Ren, Xian-Wen Yuan, Yi-Tao Ding World journal of gastroenterology : WJG 2012 new
Characterization of the DNA primase complex isolated from the archaeon, Thermococcus kodakaraensis. Wiebke Chemnitz Galal, Miao Pan, Zvi Kelman, Jerard Hurwitz The Journal of biological chemistry 2012 topics set
Effects of Essential Oils from Herbal Plants and Citrus Fruits on DNA Polymerase Inhibitory, Cancer Cell Growth Inhibitory, Antiallergic, and Antioxidant Activities. Mai Mitoshi, Isoko Kuriyama, Hiroto Nakayama, Hironari Miyazato, Keiichiro Sugimoto, Yuko Kobayashi, Tomoko Jippo, Kazuki Kanazawa, Hiromi Yoshida, Yoshiyuki Mizushina Journal of agricultural and food chemistry 2012 new
Inhibitory effects of catechin derivatives on mammalian DNA polymerase and topoisomerase activities and mouse one-cell zygote development. Naoko Yoshida, Isoko Kuriyama, Hiromi Yoshida, Yoshiyuki Mizushina Journal of bioscience and bioengineering 2012 new
Solution structure and conformational dynamics of deoxyxylonucleic acids (dXNA): an orthogonal nucleic acid candidate. Mohitosh Maiti, Vanessa Siegmund, Mikhail Abramov, Eveline Lescrinier, Helmut Rosemeyer, Mathy Froeyen, Amutha Ramaswamy, Arnout Ceulemans, Andreas Marx, Piet Herdewijn Chemistry (Weinheim an der Bergstrasse, Germany) 2012 new
Structural basis for the interaction of a hexameric replicative helicase with the regulatory subunit of human DNA polymerase α-primase. Bo Zhou, Diana R Arnett, Xian Yu, Aaron Brewster, Gregory A Sowd, Charlies L Xie, Stefan Vila, Dahai Gai, Ellen Fanning, Xiaojiang S Chen The Journal of biological chemistry 2012 new
Recent advances in thymidine kinase 2 (TK2) inhibitors and new perspectives for potential applications. Eva-María Priego, Anna Karlsson, Federico Gago, María-José Camarasa, Jan Balzarini, María-Jesús Pérez-Pérez Current pharmaceutical design 2012 pols set
DNA Polymerase β Gap-filling Translesion DNA Synthesis. Parvathi Chary, William A Beard, Samuel H Wilson, R Stephen Lloyd Chemical research in toxicology 2012 pols set
In-fusion® cloning with vaccinia virus DNA polymerase. Chad R Irwin, Andrew Farmer, David O Willer, David H Evans Methods in molecular biology (Clifton, N.J.) 2012 pols set
Signal amplified strategy based on target-induced strand release coupling cleavage of nicking endonuclease for the ultrasensitive detection of ochratoxin A. Xu Hun, Fang Liu, Zhenhua Mei, Lifeng Ma, Zhouping Wang, Xiliang Luo Biosensors & bioelectronics 2012 topics set
Thioredoxin, the Processivity Factor, Sequesters an Exposed Cysteine in the Thumb Domain of Bacteriophage T7 DNA Polymerase. Ngoc Quang Tran, Seung-Joo Lee, Barak Akabayov, Donald E Johnson, Charles C Richardson The Journal of biological chemistry 2012 topics set
DNA polymerase beta (pol β) inhibitors: a comprehensive overview. KH Barakat, MM Gajewski, JA Tuszynski Drug discovery today 2012 topics set
POLG mutation in a patient with cataracts, early-onset distal muscle weakness and atrophy, ovarian dysgenesis and 3-methylglutaconic aciduria. MR Bekheirnia, Weiming Zhang, T Eble, A Willis, A Shaibani, Lee-Jun C Wong, F Scaglia, SU Dhar Gene 2012 topics set
Pol β associated complex and base excision repair factors in mouse fibroblasts. Rajendra Prasad, Jason G Williams, Esther W Hou, Samuel H Wilson Nucleic acids research 2012 new
DNA polymerase beta is involved in the protection against the cytotoxicity and genotoxicity of cigarette smoke. Jie Cui, Wei Zhao, Xin Xu, Mo Yang, Yaou Ren, Zhenzhong Zhang Environmental toxicology and pharmacology 2012 new
Escherichia coli DNA polymerase IV (Pol IV), but not Pol II, dynamically switches with a stalled Pol III* replicase. Justin M H Heltzel, Robert W Maul, David W Wolff, Mark D Sutton Journal of bacteriology 2012 pols set
DNA base excision repair: a mechanism of trinucleotide repeat expansion. Yuan Liu, Samuel H Wilson Trends in biochemical sciences 2012 complete Yuan Liu*
A Support Vector Machine Based Method to Predict Success for Polymerase Chain Reactions. Xiaoqing Yu, Xiaoqi Zheng, Liangyu Meng, Chun Li, Jun Wang Combinatorial chemistry & high throughput screening 2012 pols set
Catalytic Effects of Mutations of Distant Protein Residues in Human DNA Polymerase β: Theory and Experiment. Martin Klvana, Drew L Murphy, Petr Jerabek, Myron F Goodman, Arieh Warshel, Joann B Sweasy, Jan Florian Biochemistry 2012 new
Biochemical Mechanism of HIV-1 Resistance to Rilpivirine. Kamalendra Singh, Bruno Marchand, Devendra K Rai, Bechan Sharma, Eleftherios Michailidis, Emily M Ryan, Kayla B Matzek, Maxwell D Leslie, Ariel N Hagedorn, Zhongjie Li, Pieter R Norden, Atsuko Hachiya, Michael A. Parniak, Hong-Tao Xu, Mark A. Wainberg, Stefan G Sarafianos The Journal of biological chemistry 2012 topics set
DNA polymerase zeta generates clustered mutations during bypass of endogenous DNA lesions in Saccharomyces cerevisiae. Jana E Stone, Scott A Lujan, Thomas A Kunkel, Thomas A Kunkel Environmental and molecular mutagenesis 2012 topics set
Mutations in human DNA polymerase γ confer unique mechanisms of catalytic deficiency that mirror the disease severity in mitochondrial disorder patients. Christal D Sohl, Rajesh Kasiviswanathan, William C Copeland, Karen S Anderson Human molecular genetics 2012 topics set
Structures of dNTP Intermediate States during DNA Polymerase Active Site Assembly. Bret D Freudenthal, William A Beard, Samuel H Wilson Structure (London, England : 1993) 2012 topics set
Quantitative analysis of the mutagenic potential of 1-aminopyrene-DNA adduct bypass catalyzed by Y-family DNA polymerases. Shanen M Sherrer, DJ Taggart, Lindsey R Pack, Chanchal K Malik, Ashis K Basu, Zucai Suo Mutation research 2012 topics set
DNA Polymerase β Variant Ile260Met Generates Global Gene Expression Changes Related to Cellular Transformation. Katherine A Donigan, David Tuck, Vince Schulz, Joann B Sweasy Mutagenesis 2012 topics set
Structure-based bioisosterism design, synthesis and biological evaluation of novel 1,2,4-triazin-6-ylthioacetamides as potent HIV-1 NNRTIs. Peng Zhan, Xincang Li, Zhongjie Li, Xuwang Chen, Ye Tian, Wenmin Chen, Xinyong Liu, Christophe Pannecouque, Erik De Clercq Bioorganic & medicinal chemistry letters 2012 pols set
Modeling translocation dynamics of strand displacement DNA synthesis by DNA polymerase I. Ping Xie Journal of molecular modeling 2012 topics set
Inhibitory effect of novel somatostatin peptide analogues on human cancer cell growth based on the selective inhibition of DNA polymerase β Isoko Kuriyama, Anna Miyazaki, Yuko Tsuda, Hiromi Yoshida, Yoshiyuki Mizushina Bioorganic & medicinal chemistry 2012 new
Exonuclease 1 preferentially repairs mismatches generated by DNA polymerase α Sascha E Liberti, Andres A Larrea, Thomas A Kunkel DNA repair 2012 new
Age-related decline in DNA polymerase β activity in rat brain and tissues. V N Vyjayanti, Umakanta Swain, Kalluri Subba Rao Neurochemical research 2012 topics set
The C-terminal domain of human Rev1 contains independent binding sites for DNA polymerase η and Rev7 subunit of polymerase ζ. Yulia Pustovalova, Irina Bezsonova, Dmitry M Korzhnev FEBS letters 2012 pols set
Mutations conferring resistance to viral DNA polymerase inhibitors in camelpox virus give different drug-susceptibility profiles in vaccinia virus. Sophie Duraffour, Graciela Andrei, Dimitri Topalis, Marcela Krečmerová, Jean-Marc Crance, Daniel Garin, Robert Snoeck Journal of virology 2012 topics set
The Pre-NH2-Terminal Domain of the Herpes Simplex Virus 1 DNA Polymerase Catalytic Subunit is Required for Efficient Viral Replication. Shariya L Terrell, Donald M Coen Journal of virology 2012 new
Mechanism of Replicative DNA Polymerase Delta Pausing and a Potential Role for DNA Polymerase Kappa in Common Fragile Site Replication. Erin Walsh, Xiaoxiao Wang, Marietta Y W T Lee, Kristin A Eckert Journal of molecular biology 2012 new
DNA polymerase μ is a global player in the repair of non-homologous end-joining substrates. Romain Chayot, Benjamin Montagne, Miria Ricchetti DNA repair 2012 new
Selective disruption of the DNA polymerase III α-β complex by the umuD gene products. MC Silva, P Nevin, EA Ronayne, PJ Beuning Nucleic acids research 2012 topics set
Roles of the Y-family DNA polymerase Dbh in accurate replication of the Sulfolobus genome at high temperature. Cynthia J Sakofsky, Patricia L Foster, Dennis W Grogan DNA repair 2012 new
DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions. Huseyin Saribasak, Robert W Maul, Zheng Cao, William W Yang, Dominik Schenten, Sven Kracker, Patricia J Gearhart The Journal of experimental medicine 2012 complete Patricia J Gearhart*
Structural Basis for Differential Insertion Kinetics of dNMPs Opposite a Difluorotoluene Nucleotide Residue. Shuangluo Xia, Soo Hyun Eom, William H Konigsberg, Jianhong Wang Biochemistry 2012 pols set
DNA polymerase beta from Trypanosoma cruzi is involved in kinetoplast DNA replication and repair of oxidative lesions. Bruno Luiz Fonseca Schamber-Reis, Sheila Cristina Nardelli, Carlos Gustavo Régis-Silva, Priscila Carneiro Campos, Paula Gonçalves Cerqueira, Sabrina Almeida Lima, Glória Regina Franco, Andréa Mara Macedo, Sergio Danilo Junho Pena, Christophe Cazaux, Jean-Sébastien Hoffmann, Maria Cristina Machado Motta, Sergio Schenkman, Santuza Maria Ribeiro Teixeira, Carlos Renato Machado Molecular and biochemical parasitology 2012 pols set
Deregulated expression of DNA polymerase β is involved in the progression of genomic instability. Qingying Luo, Yanhao Lai, Shukun Liu, Mei Wu, Yuan Liu, Zhenzhong Zhang Environmental and molecular mutagenesis 2012 new
Kinetic Analysis of the Bypass of a Bulky DNA Lesion Catalyzed by Human Y-family DNA Polymerases. Shanen M Sherrer, Laura E Sanman, Cynthia X Xia, Eric R Bolin, Chanchal K Malik, Georgia Efthimiopoulos, Ashis K Basu, Zucai Suo Chemical research in toxicology 2012 topics set
Reading DNA at single-nucleotide resolution with a mutant MspA nanopore and phi29 DNA polymerase. Elizabeth A Manrao, Ian M Derrington, Andrew H Laszlo, Kyle W Langford, Matthew K Hopper, Nathaniel Gillgren, Mikhail Pavlenok, Michael Niederweis, Jens H Gundlach Nature biotechnology 2012 pols set
Targeting DNA polymerase ß for therapeutic intervention. Eva M Goellner, David Svilar, Karen H Almeida, Robert W Sobol Current molecular pharmacology 2012 new
Characterization of catalytic carboxylate triad in non-replicative DNA polymerase III (pol E) of Geobacillus kaustophilus HTA. Cemal Sandalli, Kamalendra Singh, Mukund J Modak Cellular and molecular biology (Noisy-le-Grand, France) 2012 topics set
Biological relevance of DNA polymerase β and translesion synthesis polymerases to cancer and its treatment. Nils H Nicolay, Thomas Helleday, Ricky A Sharma Current molecular pharmacology 2012 new
Stabilization of the Escherichia coli DNA polymerase III ε subunit by the θ subunit favors in vivo assembly of the Pol III catalytic core. Emanuele Conte, Gabriele Vincelli, Roel M Schaaper, Daniela Bressanin, Alessandra Stefan, Fabrizio Dal Piaz, Alejandro Hochkoeppler Archives of biochemistry and biophysics 2012 topics set
Synthesis and biological evaluation of piperidine-substituted triazine derivatives as HIV-1 non-nucleoside reverse transcriptase inhibitors. Xuwang Chen, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu European journal of medicinal chemistry 2012 pols set
Multi-domain Protein Solves the Folding Problem by Multi-funnel Combined Landscape: Theoretical Investigation of a Y-Family DNA Polymerase. Yong Wang, Xiakun Chu, Zucai Suo, Erkang Wang, Jin Wang Journal of the American Chemical Society 2012 pols set
Human DNA polymerase λ catalyzes lesion bypass across benzo[a]pyrene-derived DNA adduct during base excision repair. Lidia V Skosareva, Natalia A Lebedeva, Nadejda I Rechkunova, Alexander Kolbanovskiy, Nicholas E Geacintov, Olga I Lavrik DNA repair 2012 topics set
Host cell nucleolin is required to maintain the architecture of human cytomegalovirus replication compartments. Blair L Strang, Steeve Boulant, Tomas Kirchhausen, Donald M Coen mBio 2012 topics set
MsDpo4-a DinB Homolog from Mycobacterium smegmatis-Is an Error-Prone DNA Polymerase That Can Promote G:T and T:G Mismatches. Amit Sharma, Deepak T Nair Journal of nucleic acids 2012 topics set
Chiral resolution, absolute configuration assignment and biological activity of racemic diarylpyrimidine CH(OH)-DAPY as potent nonnucleoside HIV-1 reverse transcriptase inhibitors. Shuang-Xi Gu, Zhi-Ming Li, Xiao-Dong Ma, Shi-Qiong Yang, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque European journal of medicinal chemistry 2012 pols set
(Z)-5-(4-methoxybenzylidene)thiazolidine-2,4-dione protects rats from carbon tetrachloride-induced liver injury and fibrogenesis. Zhi-Zhi Chen, Zheng-Lin Wang, Chong-Yang Deng, Hao Zheng, Xian-Huo Wang, Liang Ma, Xia Ye, Ying-Hua Ma, Cai-Feng Xie, Li-Juan Chen, Yu-Quan Wei World journal of gastroenterology : WJG 2012 new
Regulation of oxidative DNA damage repair: The adenine:8-oxo-guanine problem. Enni Markkanen, Ulrich Hübscher, Barbara van Loon Cell cycle (Georgetown, Tex.) 2012 new
A DNA lesion alters the global conformational dynamics of a Y-Family DNA polymerase during catalysis. Brian A Maxwell, Cuiling Xu, Zucai Suo The Journal of biological chemistry 2012 new
Antifungal properties of Japanese cedar essential oil from waste wood chips made from used sake barrels. Yoshifumi Takao, Isoko Kuriyama, Tasuku Yamada, Haruhiko Mizoguchi, Hiromi Yoshida, Yoshiyuki Mizushina Molecular medicine reports 2012 new
NMR structure and dynamics of the C-terminal domain from human Rev1 and its complex with Rev1 interacting region of DNA polymerase η. Alexandra Pozhidaeva, Yulia Pustovalova, Sanjay D'Souza, Irina Bezsonova, Graham C Walker, Dmitry M Korzhnev Biochemistry 2012 new
How conformational dynamics of DNA polymerase select correct substrates: experiments and simulations. Serdal Kirmizialtin, Virginia Nguyen, Kenneth A Johnson, Ron Elber Structure (London, England : 1993) 2012 pols set
β,γ-CHF- and β,γ-CHCl-dGTP diastereomers: synthesis, discrete 31P NMR signatures and absolute configurations of new stereochemical probes for DNA polymerases. Yue Wu, Valeria M Zakharova, Boris A Kashemirov, Myron F Goodman, Vinod K Batra, Samuel H Wilson, Charles E McKenna Journal of the American Chemical Society 2012 new
The PAD region in the mycobacterial DinB homologue MsPolIV exhibits positional heterogeneity. Amit Sharma, V Subramanian, Deepak T Nair Acta crystallographica. Section D, Biological crystallography 2012 topics set
Critical amino acids in Escherichia coli UmuC responsible for sugar discrimination and base-substitution fidelity. Alexandra Vaisman, Wojciech Kuban, John P McDonald, Kiyonobu Karata, Wei Wen Yang, Myron F Goodman, Roger Woodgate Nucleic acids research 2012 pols set
Synthesis, Biological Activity, and ADME Properties of Novel S-DABOs/N-DABOs as HIV Reverse Transcriptase Inhibitors. Marco Radi, Mafalda Pagano, Luigi Franchi, Daniele Castagnolo, Silvia Schenone, Gianni Casaluce, Claudio Zamperini, Elena Dreassi, Giovanni Maga, Alberta Samuele, Encarna Gonzalo, B Clotet, José A Esté, Maurizio Botta ChemMedChem 2012 pols set
2-(Alkyl/Aryl)Amino-6-Benzylpyrimidin-4(3H)-ones as Inhibitors of Wild-Type and Mutant HIV-1: Enantioselectivity Studies. Dante Rotili, Alberta Samuele, Domenico Tarantino, Rino Ragno, Ira Musmuca, Flavio Ballante, Giorgia Botta, Ludovica Morera, Marco Pierini, Roberto Cirilli, Maxim B Nawrozkij, Emmanuel Gonzalez, B Clotet, Marino Artico, José A Esté, Giovanni Maga, Antonello Mai Journal of medicinal chemistry 2012 pols set
Disclosing the in vivo organization of a viral histone-like protein in Bacillus subtilis mediated by its capacity to recognize the viral genome. Isabel Holguera, David Ballesteros-Plaza, Daniel Muñoz-Espín, Margarita Salas Proceedings of the National Academy of Sciences of the United States of America 2012 new
HIV-1 and HIV-2 Reverse Transcriptases: Different Mechanisms of Resistance to Nucleoside Reverse Transcriptase Inhibitors. Paul L Boyer, Patrick K Clark, Stephen H Hughes Journal of virology 2012 pols set
Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase {varepsilon} in rolling circle DNA synthesis. Young-Hoon Kang, Wiebke Chemnitz Galal, A Farina, Inger Tappin, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 2012 new
Complete sequence analysis of 18S rDNA based on genomic DNA extraction from individual Demodex mites (Acari: Demodicidae). Ya-E Zhao, Ji-Ru Xu, Li Hu, Li-Ping Wu, Zheng-Hang Wang Experimental parasitology 2012 new
Identification of Pold2 as a novel interaction partner of protein inhibitor of activated STAT2. Ying Zheng, Shudong Sheng, Haiyan Wang, Xiaoqing Jia, Yanqiu Hu, Yayun Qian, Yongze Zhu, Jianjun Wang International journal of molecular medicine 2012 new
Substrate-Dependent Millisecond Domain Motions in DNA Polymerase β Rebecca B Berlow, Monalisa Swain, Shibani Dalal, Joann B Sweasy, J Patrick Loria Journal of molecular biology 2012 new
Kinetic Basis for Differing Response to an Oxidative Lesion by a Replicative and a Lesion Bypass DNA Polymerase from Solfolobus Solfataricus. Brian A Maxwell, Zucai Suo Biochemistry 2012 new
Monogalactosyl diacylglycerol, a replicative DNA polymerase inhibitor, from spinach enhances the anti-cell proliferation effect of gemcitabine in human pancreatic cancer cells. Hiroaki Akasaka, Ryohei Sasaki, Kenji Yoshida, Izumi Takayama, Tsuyoshi Yamaguchi, Hiromi Yoshida, Yoshiyuki Mizushina Biochimica et biophysica acta 2012 new
Escherichia coli DNA polymerase III is responsible for the high level of spontaneous mutations in mutT strains. Masami Yamada, Masatomi Shimizu, Atsushi Katafuchi, Petr Grúz, Shingo Fujii, Yukio Usui, Robert P P Fuchs, Takehiko Nohmi Molecular microbiology 2012 pols set
DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ. Andrey G Baranovskiy, Artem G Lada, Hollie M Siebler, Yongqing Zhang, Youri I Pavlov, Tahir H Tahirov The Journal of biological chemistry 2012 new
A transposon-derived DNA polymerase from Entamoeba histolytica displays intrinsic strand displacement, processivity and lesion bypass. Guillermo Pastor-Palacios, Varinia López-Ramírez, Cesar S Cardona-Felix, Luis G Brieba PloS one 2012 new
In vitro-selected drug-resistant varicella-zoster virus mutants in the thymidine kinase and DNA polymerase genes yield novel phenotype-genotype associations and highlight differences between antiherpesvirus drugs. Gracíela Andrei, Dimitri Topalis, Pierre Fiten, Christopher McGuigan, Jan Balzarini, Ghislain Opdenakker, Robert Snoeck Journal of virology 2012 new
Y265C DNA polymerase beta knockin mice survive past birth and accumulate base excision repair intermediate substrates. Alireza G Senejani, Shibani Dalal, Yanfeng Liu, Timothy P Nottoli, James M McGrath, Connor S Clairmont, Joann B Sweasy Proceedings of the National Academy of Sciences of the United States of America 2012 new
Dysregulation of DNA polymerase κ recruitment to replication forks results in genomic instability. Mathew Jk Jones, Luca Colnaghi, Tony T Huang The EMBO journal 2012 topics set
Balancing Antiviral Potency and Host Toxicity: Identifying a Nucleotide Inhibitor with an Optimal Kinetic Phenotype for HIV-1 Reverse Transcriptase. Christal D Sohl, Rajesh Kasiviswanathan, Jiae Kim, Ugo Pradere, Raymond F Schinazi, William C Copeland, Hiroyuki Mitsuya, Masanori Baba, Karen S Anderson Molecular pharmacology 2012 topics set
Genotypic characterization of herpes simplex virus DNA polymerase UL42 processivity factor. Sonia Burrel, Zaïna Aït-Arkoub, Henri Agut, David Boutolleau Antiviral research 2012 topics set
Low fidelity bypass of O2-(3-pyridyl)-4-oxobutylthymine, the most persistent bulky adduct produced by the tobacco specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by model polymerases. Prakasha Gowda A S, Gowdahalli Krishnegowda, Zucai Suo, Shantu G Amin, Thomas E Spratt Chemical research in toxicology 2012 topics set
Anti-Interleukin-10R1 Monoclonal Antibody Enhances Bacillus Calmette-Guérin Induced T-Helper Type 1 Immune Responses and Antitumor Immunity in a Mouse Orthotopic Model of Bladder Cancer. Nathan A Bockholt, Matthew J Knudson, Jonathan R Henning, José L Maymí, Peter Weady, George J Smith, Michael D Eisenbraun, James D Fraser, Michael E O'Donnell, Yi Luo The Journal of urology 2012 new
Ribonucleotides and manganese ions improve non-homologous end joining by human Polμ Maria Jose Martin, Maria V Garcia-Ortiz, Veronica Esteban, Luis Blanco Nucleic acids research 2012 pols set
DNA polymerase-β mediates the neurogenic effect of β-amyloid protein in cultured subventricular zone neurospheres. Marco Calafiore, Agata Copani, Wenbin Deng Journal of neuroscience research 2012 topics set
Amino acid templating mechanisms in selection of nucleotides opposite abasic sites by a family a DNA polymerase. Samra Obeid, Wolfram Welte, Kay Diederichs, Andreas Marx The Journal of biological chemistry 2012 partial results
Structural basis of human DNA polymerase η-mediated chemoresistance to cisplatin. Yaofeng Zhao, Christian Biertümpfel, Mark T Gregory, Yue-Jin Hua, Fumio Hanaoka, Wei Wen Yang Proceedings of the National Academy of Sciences of the United States of America 2012 topics set
Antiviral therapies: Focus on hepatitis B reverse transcriptase. Eleftherios Michailidis, Karen A Kirby, Atsuko Hachiya, Wangdon Yoo, Sun Pyo Hong, Soo-Ok Kim, William R Folk, Stefan G Sarafianos The international journal of biochemistry & cell biology 2012 topics set
Overexpression of DNA polymerase iota (Polι) in esophageal squamous cell carcinoma. Jundong Zhou, Shuyu Zhang, Ling Xie, Pengfei Liu, Fang Xie, Jinchang Wu, Jianping Cao, Wei-Qun Ding Cancer science 2012 topics set
A Mutation Deleting Sequences Encoding the Amino Terminus of human Cytomegalovirus UL84 impairs Interaction with UL44 and Capsid Localization. Blair L Strang, Brian J Bender, Mayuri Sharma, Jean M Pesola, Rebecca L Sanders, Deborah H Spector, Donald M Coen Journal of virology 2012 pols set
RNase H2-Initiated Ribonucleotide Excision Repair. Justin L Sparks, Hyongi Chon, Susana M Cerritelli, Thomas A Kunkel, Erik Johansson, Robert J Crouch, Peter M J Burgers Molecular cell 2012 new
DNA polymerase ζ is a major determinant of resistance to platinum-based chemotherapeutic agents. S Sharma, Nicholas A Shah, Ariell M Joiner, Katelyn H Roberts, CE Canman Molecular pharmacology 2012 topics set
Effects of N2-Alkylguanine, O6-Alkylguanine, and Abasic Lesions on DNA Binding and Bypass Synthesis by the Euryarchaeal B-family DNA Polymerase Vent (exo-). Seonhee Lim, Insil Song, F Peter Guengerich, Jeong-Yun Choi Chemical research in toxicology 2012 topics set
Structure of human DNA polymerase iota and the mechanism of DNA synthesis. A V Makarova, A V Kulbachinskiy Biochemistry. Biokhimii͡a 2012 topics set
The HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors (Part V ☆ ): Capravirine and Its Analogues. Xincang Li, Peng Zhan, Erik De Clercq, Xinyong Liu Current medicinal chemistry 2012 pols set
Dihydro-alkoxyl-benzyl-oxopyrimidine derivatives (DABOs) as non-nucleoside reverse transcriptase inhibitors: an update review (2001-2011). Shiqiong Yang, Fen-Er Chen, Erik De Clercq Current medicinal chemistry 2012 pols set
Escherichia coli UmuC active site mutants: Effects on translesion DNA synthesis, mutagenesis and cell survival. Wojciech Kuban, Alexandra Vaisman, John P McDonald, Kiyonobu Karata, Wei Wen Yang, Myron F Goodman, Roger Woodgate DNA repair 2012 topics set
The catalytic cycle for ribonucleotide incorporation by human DNA Pol λ Rajendrakumar A Gosavi, Andrea F Moon, Thomas A Kunkel, Lars C Pedersen, Katarzyna Bebenek Nucleic acids research 2012 topics set
Accurate and Efficient Bypass of 8,5'-Cyclopurine-2'-Deoxynucleosides by Human and Yeast DNA Polymerase η Ashley L Swanson, Jianshuang Wang, Yinsheng Wang Chemical research in toxicology 2012 topics set
DNA Mismatch Synthesis Complexes Provide Insights into Base Selectivity of a B Family DNA Polymerase. Shuangluo Xia, Jianhong Wang, William H Konigsberg Journal of the American Chemical Society 2012 new
Involvement of Werner syndrome protein in MUTYH-mediated repair of oxidative DNA damage. Radhakrishnan Kanagaraj, Prasanna Parasuraman, Boris Mihaljevic, Barbara van Loon, Kamila Burdova, Christiane König, Antonia Furrer, Vilhelm A Bohr, Ulrich Hübscher, Pavel Janscak Nucleic acids research 2012 topics set
DNA polymerase α (swi7) and the flap endonuclease Fen1 (rad2) act together in the S-phase alkylation damage response in S. pombe. Milana Koulintchenko, Sonya Vengrova, Trevor Eydmann, Prakash Arumugam, Jacob Z Dalgaard PloS one 2012 topics set
BRCT domain of DNA polymerase μ has DNA-binding activity and promotes the DNA polymerization activity. Takuro Matsumoto, Kaori Go, Mariko Hyodo, Kotaro Koiwai, So Maezawa, Takahide Hayano, Masahiro Suzuki, Osamu Koiwai Genes to cells : devoted to molecular & cellular mechanisms 2012 topics set
[Mutation analysis of the HBV reverse transcriptase in nucleos(t)ide-treated patients with chronic HBV infection]. Xiu-Juan Jiao, Xun Peng, Xiu-Min Jiao, Jin-Sheng Wang, Xie-Wen Sun, Pei-Li Zhao, Shou-Yun Wang, Jia-Qun Liu, Tong Li, Jing-Xian Yang Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 2012 topics set
Dynamics of the translocation step measured in individual DNA polymerase complexes. Kate R Lieberman, Joseph M Dahl, Ai H Mai, Mark Akeson, Hongyun Wang Journal of the American Chemical Society 2012 topics set
SARS-CoV Replication Inhibitor that Interferes with the Nucleic acid Unwinding of the Viral Helicase. Adeyemi O Adedeji, Kamalendra Singh, Nicholas E Calcaterra, Marta L Dediego, Luis Enjuanes, Susan Weiss, Stefan G Sarafianos Antimicrobial agents and chemotherapy 2012 new
KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry. Karin Betz, Denis A Malyshev, Thomas Lavergne, Wolfram Welte, Kay Diederichs, Tammy J Dwyer, Phillip Ordoukhanian, Floyd E Romesberg, Andreas Marx Nature chemical biology 2012 new
Interactions of non-polar and "Click-able" nucleotides in the confines of a DNA polymerase active site. Samra Obeid, Holger Busskamp, Wolfgang Welte, Kay Diederichs, Andreas Marx Chemical communications (Cambridge, England) 2012 new
Alternariol induces DNA polymerase β expression through the PKA-CREB signaling pathway. Jimin Zhao, Kangdong Liu, Jing Lu, Junfen Ma, Xiaoyan Zhang, Yanan Jiang, Hongyan Yang, Ge Jin, Guoqiang Zhao, Mingyao Zhao, Ziming Dong International journal of oncology 2012 new
Ribonucleotide incorporation, proofreading and bypass by human DNA polymerase δ Anders R Clausen, Sufang Zhang, Peter M J Burgers, Marietta Y W T Lee, Thomas A Kunkel DNA repair 2012 new
HIV-1 reverse transcriptase (RT) polymorphism 172K, suppresses the effect of clinically relevant drug resistance mutations to both nucleoside and nonnucleoside RT inhibitors. Atsuko Hachiya, Bruno Marchand, Karen A Kirby, Eleftherios Michailidis, Xiongying Tu, Krzysztof Palczewski, Yee Tsuey Ong, Zhongjie Li, Daniel T Griffin, Matthew M Schuckmann, Junko Tanuma, Shinichi Oka, Kamalendra Singh, Eiichi N Kodama, Stefan G Sarafianos The Journal of biological chemistry 2012 topics set
Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug. V Brabec, J Malina, N Margiotta, G Natile, J Kasparkova Chemistry (Weinheim an der Bergstrasse, Germany) 2012 topics set
Exploiting the anti-HIV-1 activity of acyclovir: suppression of primary and drug-resistant HIV isolates and potentiation of the activity by ribavirin. Christophe Vanpouille, Andrea Lisco, Andrea Introini, Jean-Charles Grivel, Arshi Munawwar, Melanie Merbah, Raymond F Schinazi, Marco Derudas, Christopher McGuigan, Jan Balzarini, Leonid Margolis Antimicrobial agents and chemotherapy 2012 pols set
Analysis of mice deficient in both REV1 catalytic activity and POLH reveals an unexpected role for POLH in the generation of C to G and G to C transversions during Ig gene hypermutation. Chie Kano, Fumio Hanaoka, Ji-Yang Wang International immunology 2012 topics set
Potential of carbohydrate-binding agents as therapeutics against enveloped viruses. K O François, Jan Balzarini Medicinal research reviews 2012 pols set
Defects in mitochondrial DNA replication and human disease. William C Copeland Critical reviews in biochemistry and molecular biology 2012 new
Characterization of human DNA polymerase delta and its subassemblies reconstituted by expression in the multibac system. Yajing Zhou, Xiao Meng, Sufang Zhang, Ernest Y C Lee, Marietta Y W T Lee PloS one 2012 pols set
Inhibitors of HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity. Tatiana Ilina, Krystal Labarge, Stefan G Sarafianos, Rieko Ishima, Michael A. Parniak Biology 2012 complete Tatiana Ilina*
Pol31 and Pol32 subunits of yeast DNA polymerase δ are also essential subunits of DNA polymerase ζ Robert E Johnson, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2012 new
Replication bypass of the trans-4-Hydroxynonenal-derived (6S,8R,11S)-1,N(2)-deoxyguanosine DNA adduct by the sulfolobus solfataricus DNA polymerase IV. Surajit Banerjee, Plamen P Christov, Albena Kozekova, Carmelo J Rizzo, Martin Egli, Michael P Stone Chemical research in toxicology 2012 topics set
Identification and expression analysis of major histocompatibility complex IIB gene in orange-spotted grouper Epinephelus coioides. D Q Lu, S B Yi, Mingzhong Yao, Y W Li, X C Liu, Yongqing Zhang, H R Lin Journal of fish biology 2012 new
Suppression of NPC tumor growth by hTERTC27 polypeptide delivered through AAV plus Adv vector cocktail. Xiong Liu, Xiang-Ping Li, Ying Peng, Samuel S M Ng, Hong Yao, Zi-Feng Wang, Xiao-Mei Wang, Hsiang-Fu Kung, Marie Chia-Mi Lin Chinese journal of cancer 2012 new
Direct observation of translocation in individual DNA polymerase complexes. Joseph M Dahl, Ai H Mai, Gerald M Cherf, Nahid N Jetha, Daniel R Garalde, Andre Marziali, Mark Akeson, Hongyun Wang, Kate R Lieberman The Journal of biological chemistry 2012 pols set
Human DNA polymerase beta mutations allowing efficient abasic site bypass. Sonja Gieseking, Konrad Bergen, Francesca Di Pasquale, Kay Diederichs, Wolfram Welte, Andreas Marx The Journal of biological chemistry 2011 topics set
Rapid and sensitive detection of DNA polymerase fidelity by singly labeled smart fluorescent probes. Chen Song, Chen Zhang, Meiping Zhao Biosens Bioelectron 2011 topics set
[Identification of a novel HLA allele HLA-B*40:96]. Chuan-fu Zhu, Yongqing Zhang, Yun-long Zhuang, Yong-hong Song, Yan Liu, Xiang-min Nie Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 2011 new
Influence of chitosan nanofiber scaffold on porcine endogenous retroviral expression and infectivity in pig hepatocytes. Bing Han, Xiao-Lei Shi, Jiang-Qiang Xiao, Yongqing Zhang, Xue-Hui Chu, Jin-Yang Gu, Jia-Jun Tan, Zhong-Ze Gu, Yi-Tao Ding World journal of gastroenterology : WJG 2011 new
Frequent detection of infectious xenotropic murine leukemia virus (XMLV) in human cultures established from mouse xenografts. Yu-An Zhang, Anirban Maitra, Jer-Tsong Hsieh, Charles M Rudin, Craig D Peacock, Collins Karikari, Rolf A Brekken, Victor Stastny, Boning Gao, Luc Girard, Ignacio Wistuba, Eugene Frenkel, John D Minna, Adi F Gazdar Cancer biology & therapy 2011 new
Extending the activities of human nucleus pulposus cells with recombinant adeno-associated virus vector-mediated human telomerase reverse transcriptase gene transfer. Jianhong Wu, Deli Wang, Chao Zhang, Chaofeng Wang, Yongqing Zhang, Hongkui Xin, Qing He, Dike Ruan Tissue engineering. Part A 2011 new
Construction, modification and evaluation of apolipoprotein A-I promoter-driven shRNA expression vectors against hTERT. Xueling Ren, Yue Ma, Min Xu, Tingting Chen, Zhenzhong Zhang, Yongqing Zhang Plasmid 2011 new
A new proofreading mechanism for lesion bypass by DNA polymerase-λ Emmanuele Crespan, Giovanni Maga, Ulrich Hübscher EMBO reports 2011 topics set
Cloning, expression, purification, crystallization and preliminary crystallographic analysis of MsDpo4: a Y-family DNA polymerase from Mycobacterium smegmatis. Amit Sharma, Deepak T Nair Acta crystallographica. Section F, Structural biology and crystallization communications 2011 topics set
Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase α. Jia Sun, Yuting Yang, Ke Wan, Ninghui Mao, Tai-Yuan Yu, Yi-Chien Lin, Diane C DeZwaan, Brian C Freeman, Jing-Jer Lin, Neal F Lue, Ming Lei Cell research 2011 new
Synthesis and anti-HIV activity of aryl-2-[(4-cyanophenyl)amino]-4-pyrimidinone hydrazones as potent non-nucleoside reverse transcriptase inhibitors. Xiao-Dong Ma, Shi-Qiong Yang, Shuang-Xi Gu, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque ChemMedChem 2011 pols set
1-[2-(2-Benzoyl- and 2-benzylphenoxy)ethyl]uracils as potent anti-HIV-1 agents. Mikhail S Novikov, Olga N Ivanova, Alexander V Ivanov, Alexander A Ozerov, Vladimir T Valuev-Elliston, Kartik Temburnikar, Galina V Gurskaya, Sergey N Kochetkov, Christophe Pannecouque, Jan Balzarini, Katherine L Seley-Radtke Bioorganic & medicinal chemistry 2011 pols set
7-Alkyl-N(2)-substituted-3-deazaguanines. Synthesis, DNA polymerase III inhibition and antibacterial activity. Wei-Chu Xu, George E Wright, Neal C Brown, Zheng-Yu Long, Cheng-Xin Zhi, Sofya Dvoskin, Joseph J Gambino, Marjorie H Barnes, Michelle M Butler Bioorganic & medicinal chemistry letters 2011 complete George E Wright*
Phenylalanine 171 is a molecular brake for translesion synthesis across benzo[a]pyrene-guanine adducts by human DNA polymerase kappa. Akira Sassa, Naoko Niimi, Hirofumi Fujimoto, Atsushi Katafuchi, Petr Grúz, Manabu Yasui, Ramesh C Gupta, Francis Johnson, Toshihiro Ohta, Takehiko Nohmi Mutation research 2011 topics set
Topical tenofovir, a microbicide effective against HIV, inhibits herpes simplex virus-2 replication. Graciela Andrei, Andrea Lisco, Christophe Vanpouille, Andrea Introini, Emanuela Balestra, Joost van den Oord, Tomas Cihlar, CF Perno, Robert Snoeck, Leonid Margolis, Jan Balzarini Cell host & microbe 2011 pols set
Synthesis and biological evaluation of 6-substituted 5-alkyl-2-(phenylaminocarbonylmethylthio)pyrimidin-4(3H)-ones as potent HIV-1 NNRTIs. Mingyan Yu, Zhongjie Li, Shuai Liu, Erkang Fan, Christophe Pannecouque, Erik De Clercq, Xinyong Liu ChemMedChem 2011 pols set
A 40-year journey in search of selective antiviral chemotherapy. Erik De Clercq Annual review of pharmacology and toxicology 2011 pols set
The N-terminal region of the bacterial DNA polymerase PolC features a pair of domains, both distantly related to domain V of the DNA polymerase III τ subunit. Kęstutis Timinskas The FEBS journal 2011 new
Interactions of the DNA polymerase X from African Swine Fever Virus with the ssDNA. Properties of the total DNA-binding site and the strong DNA-binding subsite. Maria J Jezewska, Michal R Szymanski, Wlodzimierz Bujalowski Biophysical chemistry 2011 new
The design, synthesis and biological evaluations of C-6 or C-7 substituted 2-hydroxyisoquinoline-1,3-diones as inhibitors of hepatitis C virus. Yue-Lei Chen, Jing Tang, Matthew J Kesler, Yuk Y Sham, Robert Vince, Robert J Geraghty, Zhengqiang Wang Bioorganic & medicinal chemistry 2011 new
Liquid chromatography-mass spectrometry analysis of DNA polymerase reaction products. Goutam Chowdhury, F Peter Guengerich Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.] 2011 new
RNAi targeting of hTERT gene expression induces apoptosis and inhibits the proliferation of lung cancer cells. Linhu Ge, Wenlong Shao, Yongqing Zhang, Yuan Qiu, Dong Cui, Donghai Huang, Zhansheng Deng Oncology letters 2011 new
Transmission dynamics of the M184V drug resistance mutation in primary HIV infection. Mark A. Wainberg, Daniela D Moisi, Maureen Oliveira, Thomas D'Aquin Toni, Bluma G Brenner The Journal of antimicrobial chemotherapy 2011 pols set
The human immunodeficiency virus-1 genotype diversity and drug resistance mutations profile of volunteer blood donors from Chinese blood centers. Peibin Zeng, Jingxing Wang, Yi Huang, Xiaoming Guo, Jinming Li, Guoxin Wen, Tonghan Yang, Zhongqiao Yun, Miao He, Yu Liu, Yuzhe Yuan, Jane Schulmann, Simone Glynn, Paul Ness, J Brooks Jackson, Hua Shan Transfusion 2011 pols set
Generation of a Mono-ubiquitinated PCNA Mimic by Click Chemistry. Silvia Eger, Benoît Castrec, Ulrich Hübscher, Martin Scheffner, Marina Rubini, Andreas Marx Chembiochem : a European journal of chemical biology 2011 new
Terminal protein-primed amplification of heterologous DNA with a minimal replication system based on phage {Phi}29. Mario Mencía, Pablo Gella, Ana Camacho, Miguel de Vega, Margarita Salas Proceedings of the National Academy of Sciences of the United States of America 2011 topics set
Characterization of the E138K resistance mutation in HIV-1 reverse transcriptase conferring susceptibility to etravirine in B and non-B HIV-1 subtypes. Eugene L Asahchop, Maureen Oliveira, Mark A. Wainberg, Bluma G Brenner, Daniela D Moisi, Thomas D'Aquin Toni, Cecile L Tremblay Antimicrobial agents and chemotherapy 2011 pols set
Compensation by the E138K mutation in HIV-1 reverse transcriptase for deficits in viral replication capacity and enzyme processivity associated with the M184I/V mutations. Hong-Tao Xu, Eugene L Asahchop, Maureen Oliveira, Peter K Quashie, Yudong Quan, Bluma G Brenner, Mark A. Wainberg Journal of virology 2011 pols set
Subtype diversity associated with the development of HIV-1 resistance to integrase inhibitors. Bluma G Brenner, Matthew Lowe, Daniela D Moisi, Isabelle Hardy, Simon Gagnon, Hugues Charest, Jean Guy Baril, Mark A. Wainberg, Michel Roger Journal of medical virology 2011 pols set
P50, the Small Subunit of DNA Polymerase Delta, Is Required for Mediation of the Interaction of Polymerase Delta Subassemblies with PCNA. Yujue Wang, Qian Zhang, Huiqing Chen, Xincang Li, Weijun Mai, Keping Chen, Sufang Zhang, Ernest Y C Lee, Marietta Y W T Lee, Yajing Zhou PloS one 2011 topics set
Sensing of replication stress and Mec1 activation act through two independent pathways involving the 9-1-1 complex and DNA polymerase ε. Fabio Puddu, Gabriele Piergiovanni, Paolo Plevani, Marco Muzi-Falconi PLoS genetics 2011 new
Distinct complexes of DNA polymerase I (Klenow fragment) for base and sugar discrimination during nucleotide substrate selection. Daniel R Garalde, Christopher A Simon, Joseph M Dahl, Hongyun Wang, Mark Akeson, Kate R Lieberman The Journal of biological chemistry 2011 complete Kate R Lieberman*
Role of human DNA polymerase κ in extension opposite from a cis-syn thymine dimer. Rodrigo Vasquez-Del Carpio, Timothy D Silverstein, Samer Lone, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Journal of molecular biology 2011 topics set
DNA polymerase beta is critical for genomic stability of sperm cells. Dawit Kidane, Shibani Dalal, Agnes Keh, Yanfeng Liu, Daniel Zelterman, Joann B Sweasy DNA repair 2011 new
Biochemical behavior of N-oxidized cytosine and adenine bases in DNA polymerase-mediated primer extension reactions. Hirosuke Tsunoda, Tomomi Kudo, Yoshiaki Masaki, Akihiro Ohkubo, Kohji Seio, Mitsuo Sekine Nucleic acids research 2011 topics set
Structural mechanism of ribonucleotide discrimination by a Y-family DNA polymerase. Kevin N Kirouac, Zucai Suo, Hong Ling Journal of molecular biology 2011 topics set
Sequence-specific stalling of DNA polymerase γ and the effects of mutations causing progressive ophthalmoplegia. Neli Atanassova, Javier Miralles Fusté, Sjoerd Wanrooij, Bertil Macao, Steffi Goffart, Stefan Bäckström, Geraldine Farge, Ivan Khvorostov, Nils-Göran Larsson, Johannes N Spelbrink, Maria Falkenberg Human molecular genetics 2011 topics set
AtPolλ, a homolog of mammalian DNA polymerase λ in Arabidopsis thaliana, is involved in the repair of UV-B induced DNA damage through the dark repair pathway. Sujit Roy, Swarup Roy Choudhury, Sanjay Kumar Singh, Kali Pada Das Plant & cell physiology 2011 topics set
A phage-encoded inhibitor of Escherichia coli DNA replication targets the DNA polymerase clamp loader. Sho T Yano, Lucia B Rothman-Denes Molecular microbiology 2011 topics set
A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase beta. De-Sheng Pei, Xiao-Jie Yang, Wei Liu, Jeroen E J Guikema, Carol E Schrader, Phyllis R Strauss Nucleic acids research 2011 new
Engineered split in Pfu DNA polymerase fingers domain improves incorporation of nucleotide gamma-phosphate derivative. Connie J Hansen, Lydia Wu, Jeffrey D Fox, Bahram Arezi, Holly H Hogrefe Nucleic acids research 2011 complete
Partial sequence of the DNA-dependent DNA polymerase gene of fowl adenoviruses: a reference panel for a general diagnostic PCR in poultry. Gyozo L Kaján, Soroush Sameti, Mária Benko Acta veterinaria Hungarica 2011 complete Gyozo L Kaján*
Mutagenesis of the human immunodeficiency virus reverse transcriptase p51 subunit defines residues contributing to vinylogous urea inhibition of Ribonuclease H activity. Suhman Chung, Jennifer T Miller, Barry C Johnson, Stephen H Hughes, Stuart F J Le Grice The Journal of biological chemistry 2011 pols set
An Abridged Transition State Model To Derive Structure, Dynamics, and Energy Components of DNA Polymerase β Fidelity. Martin Klvaňa, Petr Jeřábek, Myron F Goodman, Jan Florián Biochemistry 2011 new
Hydrogen-bonding capability of a templating difluorotoluene nucleotide residue in an RB69 DNA polymerase ternary complex. Shuangluo Xia, William H Konigsberg, Jianhong Wang Journal of the American Chemical Society 2011 topics set
Growth inhibition and chromosomal instability of cultured marsupial (opossum) cells after treatment with DNA polymerase α inhibitor. Masaharu Takemura, Tomoko Kazama, Kurumi Sakuma, Yoshiyuki Mizushina, Teruyoshi Oshima Bioscience, biotechnology, and biochemistry 2011 new
Identification of alternative binding sites for inhibitors of HIV-1 ribonuclease H through comparative analysis of virtual enrichment studies. Anthony K Felts, Krystal Labarge, Joseph David Bauman, Dishaben V Patel, Daniel M Himmel, Edward Arnold, Michael A. Parniak, Ronald M Levy Journal of chemical information and modeling 2011 pols set
Synthesis, activity, and structural analysis of novel α-hydroxytropolone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H. Suhman Chung, Daniel M Himmel, Jian-Kang Jiang, Krzysztof Wojtak, Joseph David Bauman, Jason W Rausch, Jennifer A Wilson, John A Beutler, Craig J Thomas, Edward Arnold, Stuart F J Le Grice Journal of medicinal chemistry 2011 pols set
Functional analysis of light-regulated promoter region of AtPolλ gene. Sujit Roy, Swarup Roy Choudhury, Sanjay Kumar Singh, Kali Pada Das Planta 2011 new
Discovery of cyanophage genomes which contain mitochondrial DNA polymerase. Yi-Wah Chan, Remus Mohr, Andrew D Millard, Antony B Holmes, Anthony W Larkum, Anna L Whitworth, Nicholas H Mann, David J Scanlan, Wolfgang R Hess, Martha R J Clokie Molecular biology and evolution 2011 new
Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers. Rajesh Kasiviswanathan, Margaret A Gustafson, William C Copeland, Joel N Meyer The Journal of biological chemistry 2011 partial results
Coronavirus infection induces DNA replication stress partly through interaction of its nonstructural protein 13 with the p125 subunit of DNA polymerase δ. Ling Hui Xu, Mei Huang, Shou Guo Fang, Ding Xiang Liu The Journal of biological chemistry 2011 pols set
Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination. Enni Markkanen, Barbara van Loon, Elena Ferrari, Jason L Parsons, Grigory L Dianov, Ulrich Hübscher Proceedings of the National Academy of Sciences of the United States of America 2011 topics set
The interface of transcription and DNA replication in the mitochondria. Rajesh Kasiviswanathan, Tammy R L Collins, William C Copeland Biochimica et biophysica acta 2011 new
Molecular modelling studies of new potential human DNA polymerase α inhibitors. Barbara Zdrazil, Anja Schwanke, Birte Schmitz, Monika Schäfer-Korting, Hans-Dieter Höltje Journal of enzyme inhibition and medicinal chemistry 2011 topics set
Lesion bypass by S. cerevisiae Pol ζ alone. JanaE Stone, Dinesh Kumar, SaraK Binz, Aki Inase, Shigenori Iwai, Andrei Chabes, PeterM Burgers, ThomasA Kunkel DNA repair 2011 new
Ubiquitylation of DNA polymerase λ. Enni Markkanen, Barbara van Loon, Elena Ferrari, Ulrich Hübscher FEBS letters 2011 new
Phenotypic diversity of cytomegalovirus DNA polymerase gene variants observed after antiviral therapy. Sunwen Chou Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2011 complete Sunwen Chou*
Oxidative DNA damage bypass in Arabidopsis thaliana requires DNA polymerase λ and proliferating cell nuclear antigen 2. Alessandra Amoroso, Lorenzo Concia, Caterina Maggio, Cécile Raynaud, Catherine Bergounioux, Emmanuele Crespan, Rino Cella, Giovanni Maga The Plant cell 2011 topics set
Inaccurate DNA synthesis in cell extracts of yeast producing active human DNA polymerase iota. Alena V Makarova, Corinn Grabow, Leonid V Gening, Vyacheslav Z Tarantul, Tahir H Tahirov, Tadayoshi Bessho, Youri I Pavlov PloS one 2011 pols set
Absence of biallelic TCRγ deletion predicts induction failure and poorer outcomes in childhood T-cell acute lymphoblastic leukemia. Yung-Li Yang, Chih-Cheng Hsiao, Hsuan-Yu Chen, Kai-Hsin Lin, Shiann-Tarng Jou, Jiann-Shiuh Chen, Te-Kau Chang, Jiunn-Ming Sheen, Sung-Liang Yu, Meng-Yao Lu, Chao-Neng Cheng, Kang-Hsi Wu, Shih-Chung Wang, Jiaan-Der Wang, Hsiu-Hao Chang, Shu-Rung Lin, Shu-Wha Lin, Dong-Tsamn Lin Pediatric blood & cancer 2011 new
Bypass of N²-ethylguanine by human DNA polymerase κ. Matthew G Pence, Patrick Blans, Charles N Zink, James C Fishbein, Fred W Perrino DNA repair 2011 topics set
Small Molecule Inhibitors of Human DNA Polymerase λ. Tobias Strittmatter, Bettina Bareth, Timo A Immel, Thomas Huhn, Thomas U Mayer, Andreas Marx ACS chemical biology 2011 topics set
Acylated catechin derivatives: inhibitors of DNA polymerase and angiogenesis. Yoshiyuki Mizushina, Akiko Saito, Keiko Horikawa, Noriyuki Nakajima, Akira Tanaka, Hiromi Yoshida, Kiminori Matsubara Frontiers in bioscience (Elite edition) 2011 new
Binary complex crystal structure of DNA polymerase β reveals multiple conformations of the templating 8-oxoguanine lesion. Vinod K Batra, David D Shock, William A Beard, Charles E McKenna, Samuel H Wilson Proceedings of the National Academy of Sciences of the United States of America 2011 new
A triad interaction in the fingers subdomain of DNA polymerase beta controls polymerase activity. Drew L Murphy, Joachim Jaeger, Joann B Sweasy Journal of the American Chemical Society 2011 topics set
The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism. Eugene Y Wu, Lorena S Beese The Journal of biological chemistry 2011 topics set
Involvement of residues of the 29 terminal protein intermediate and priming domains in the formation of a stable and functional heterodimer with the replicative DNA polymerase. Alicia Del Prado, Laurentino Villar, Miguel de Vega, Margarita Salas Nucleic acids research 2011 new
A257T linker region mutant of T7 helicase-primase protein is defective in DNA loading and rescued by T7 DNA polymerase. Gayatri Patel, Daniel S Johnson, Bo Sun, Manjula Pandey, Xiong Yu, Edward H Egelman, Michelle D Wang, Smita S Patel The Journal of biological chemistry 2011 pols set
Structure and mechanism of human DNA polymerase η Christian Biertümpfel, Yaofeng Zhao, Yuji Kondo, Santiago Ramón-Maiques, Mark T Gregory, Jae Young Lee, Chikahide Masutani, Alan R Lehmann, Fumio Hanaoka, Wei Wen Yang Nature 2011 topics set
Replication of ribonucleotide-containing DNA templates by yeast replicative polymerases. Danielle L Watt, Erik Johansson, Peter M J Burgers, Thomas A Kunkel DNA repair 2011 new
A Crystallographic Study of the Role of Sequence Context in Thymine Glycol Bypass by a Replicative DNA Polymerase Serendipitously Sheds Light on the Exonuclease Complex. Pierre Aller, Stéphanie Duclos, Susan S Wallace, Sylvie Doublié Journal of molecular biology 2011 new
One-year monthly survey of rotavirus, astrovirus and norovirus in three sewage treatment plants (STPs) in Beijing, China and associated health risk assessment. Xiao Q He, Li Cheng, D Y Zhang, Xiang M Xie, D H Wang, Zhengqiang Wang Water science and technology : a journal of the International Association on Water Pollution Research 2011 new
1H, 13C, and 15N NMR assignments of the Pyrococcus abyssi DNA polymerase II intein. Jiajing Liu, Zhenming Du, Clayton D Albracht, Roshni O Naidu, Kenneth V Mills, Chunyu Wang Biomolecular NMR assignments 2011 pols set
The in vitro fidelity of yeast DNA polymerase δ and polymerase ε holoenzymes during dinucleotide microsatellite DNA synthesis. Amy L Abdulovic, Suzanne E Hile, Thomas A Kunkel, Kristin A Eckert DNA repair 2011 topics set
Breaking the rules: bacteria that use several DNA polymerase IIIs. Charles S McHenry EMBO reports 2011 pols set
Bypass of Aflatoxin B(1) Adducts by the Sulfolobus solfataricus DNA Polymerase IV. Surajit Banerjee, Kyle L Brown, Martin Egli, Michael P Stone Journal of the American Chemical Society 2011 topics set
Mismatch repair-independent tandem repeat sequence instability resulting from ribonucleotide incorporation by DNA polymerase ε. Alan B Clark, Scott A Lujan, Grace E Kissling, Thomas A Kunkel DNA repair 2011 topics set
A top-down view on DNA replication and recombination from 9,000 feet above sea level. Erik Johansson, Christian Speck, Andrei Chabes Genome biology 2011 new
Studies on Human DNA Polymerase {epsilon} and GINS Complex and Their Role in DNA Replication. Vladimir P Bermudez, A Farina, V Raghavan, Inger Tappin, Jerard Hurwitz The Journal of biological chemistry 2011 pols set
Total biosynthesis of diterpene aphidicolin, a specific inhibitor of DNA polymerase α: heterologous expression of four biosynthetic genes in Aspergillus oryzae. Ryuya Fujii, Atsushi Minami, Tae Tsukagoshi, Natsuko Sato, Takehiko Sahara, Satoru Ohgiya, Katsuya Gomi, Hideaki Oikawa Bioscience, biotechnology, and biochemistry 2011 topics set
Crystal structure of DNA polymerase III beta sliding clamp from Mycobacterium tuberculosis. Wen-Jun Gui, Shi-Qiang Lin, Yuan-Yuan Chen, Xian-En Zhang, Li-Jun Bi, Tao Jiang Biochem Biophys Res Commun 2011 topics set
A model for transition of 5'-nuclease domain of DNA polymerase I from inert to active modes. Ping Xie, Jon R Sayers PloS one 2011 complete Jon R Sayers*
Strand annealing and terminal transferase activities of a B-family DNA polymerase. Zhongfeng Zuo, Hsiang-Kai Lin, Michael A Trakselis Biochemistry 2011 complete Michael A Trakselis*
Characterization of DNA polymerase β from Danio rerio by overexpression in E. coli using the in vivo/in vitro compatible pIVEX plasmid. Tomomi Ishido, Naoshi Yamazaki, Mitsuru Ishikawa, Ken Hirano Microbial cell factories 2011 topics set
DNA polymerase β as a novel target for chemotherapeutic intervention of colorectal cancer. Aruna S Jaiswal, Sanjeev Banerjee, Ritu Aneja, Fazlul H Sarkar, David A Ostrov, Satya Narayan PloS one 2011 new
Structural and mutational studies of a hyperthermophilic intein from DNA polymerase II of Pyrococcus abyssi. Zhenming Du, Jiajing Liu, Clayton D Albracht, Alice Hsu, Wen Chen, Michelle D Marieni, Kathryn M Colelli, Jennie E Williams, Julie N Reitter, Kenneth V Mills, Chunyu Wang The Journal of biological chemistry 2011 pols set
Helicase-DNA polymerase interaction is critical to initiate leading-strand DNA synthesis. Huidong Zhang, Seung-Joo Lee, B Zhu, Ngoc Quang Tran, Stanley Tabor, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 2011 topics set
Reduced stimulation of recombinant Pol {gamma} and mtDNA helicase by variants of mitochondrial single-stranded DNA-binding protein (mtSSB) correlates with defects in mtDNA Replication in animal cells. Marcos T Oliveira, Laurie S Kaguni The Journal of biological chemistry 2011 pols set
Molecular regulation of telomerase activity in aging. Craig Nicholls, He Li, Jian-Qiu Wang, Jun-Ping Liu Protein & cell 2011 pols set
A novel "eukaryote-made" thermostable DNA polymerase which is free from bacterial DNA contamination. H Niimi, M Mori, H Tabata, H Minami, Takayuki Ueno, S Hayashi, I Kitajima Journal of clinical microbiology 2011 topics set
N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide. Jiang-bo Tang, David Svilar, Ram N Trivedi, Xiao-Hong Wang, Eva M Goellner, Briana Moore, Ronald L Hamilton, Lauren A Banze, Ashley R Brown, Robert W Sobol Neuro-oncology 2011 topics set
Single-nucleotide base excision repair DNA polymerase activity in C. elegans in the absence of DNA polymerase {beta} Kenjiro Asagoshi, Wade Lehmann, Elena K Braithwaite, Lucas Santana-Santos, Rajendra Prasad, Jonathan H Freedman, Bennett Van Houten, Samuel H Wilson Nucleic acids research 2011 new
A novel ubiquitin binding mode in the S. cerevisiae translesion synthesis DNA polymerase η. Yongxing Ai, Jialiang Wang, Robert E Johnson, Lajos Haracska, Louise Prakash, Zhihao Zhuang Molecular bioSystems 2011 partial results
Role of DNA polymerase beta in the genotoxicity of arsenic. Yanhao Lai, Wei Zhao, Chen Chen, Mei Wu, Zhenzhong Zhang Environmental and molecular mutagenesis 2011 topics set
Escherichia coli processivity clamp β from DNA polymerase III is dynamic in solution. Jing Fang, John R Engen, Penny J Beuning Biochemistry 2011 topics set
Cyclopropavir Susceptibility of Cytomegalovirus DNA Polymerase Mutants Selected after Antiviral Drug Exposure. Sunwen Chou, Gail Marousek, T L Bowlin Antimicrobial agents and chemotherapy 2011 topics set
Phosphonoformic acid inhibits viral replication by trapping the closed form of the DNA polymerase. Karl E Zahn, Egor P Tchesnokov, Matthias Götte, Sylvie Doublié The Journal of biological chemistry 2011 pols set
DNA synthesis across an abasic lesion by yeast REV1 DNA polymerase. Deepak T Nair, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Journal of molecular biology 2011 new
Molecular architecture of a multifunctional MCM complex. June Sanchez-Berrondo, Pablo Mesa, Arkaitz Ibarra, Maria I Martínez-Jiménez, Luis Blanco, Juan Méndez, Jasminka Boskovic, Guillermo Montoya Nucleic acids research 2011 complete Guillermo Montoya*
Initiation of HIV reverse transcription: is enzyme flipping required? Matthias Götte Viruses 2011 pols set
Impact of primer-induced conformational dynamics of HIV-1 reverse transcriptase on polymerase translocation and inhibition. Anick Auger, Greg L Beilhartz, Siqi Zhu, Elizabeth Cauchon, Jean-Pierre Falgueyret, Jay A Grobler, Maryam Ehteshami, Matthias Götte, Roman A Melnyk The Journal of biological chemistry 2011 pols set
Inhibition of multi-drug resistant HIV-1 reverse transcriptase by nucleoside β-triphosphates. Chandravanu Dash, Yousef Ahmadibeni, Michael J Hanley, Jui Pandhare, Mathias Gotte, Stuart F J Le Grice, Keykavous Parang Bioorganic & medicinal chemistry letters 2011 pols set
Effects of mutations F61A and A62V in the fingers subdomain of HIV-1 reverse transcriptase on the translocational equilibrium. Brian J Scarth, Suzanne McCormick, Matthias Götte Journal of molecular biology 2011 pols set
The Rate of Polymerase Release upon Filling the Gap between Okazaki Fragments Is Inadequate to Support Cycling during Lagging Strand Synthesis. Paul R Dohrmann, Carol M Manhart, Christopher D Downey, Charles S McHenry Journal of molecular biology 2011 partial results
Dynamic coupling between the motors of DNA replication: hexameric helicase, DNA polymerase, and primase. Smita S Patel, Manjula Pandey, Divya Nandakumar Current opinion in chemical biology 2011 new
Mismatch repair causes the dynamic release of an essential DNA polymerase from the replication fork. Andrew D Klocko, Jeremy W Schroeder, Brian W Walsh, Justin S Lenhart, Margery L Evans, Lyle A Simmons Molecular microbiology 2011 topics set
Molecular detection of persistent postoperative circulating tumour cells in stages II and III colon cancer patients via multiple blood sampling: prognostic significance of detection for early relapse. C-Y Lu, Y-H Uen, H-L Tsai, S-C Chuang, M-F Hou, D-C Wu, S-H Hank Juo, S-R Lin, J-Y Wang British journal of cancer 2011 new
Novel structure of an N-terminal domain that is crucial for the dimeric assembly and DNA-binding of an archaeal DNA polymerase D large subunit from Pyrococcus horikoshii. Ikuo Matsui, Yuji Urushibata, Yulong Shen, Eriko Matsui, Hideshi Yokoyama FEBS letters 2011 topics set
Promiscuous DNA synthesis by human DNA polymerase θ M Hogg, AE Sauer-Eriksson, Erik Johansson Nucleic acids research 2011 topics set
In silico study of the inhibition of DNA polymerase by a novel catalpol derivative. Osvaldo A Martin, Hugo A Garro, Marcela B Kurina Sanz, Carlos Rodolfo Pungitore, Carlos E Tonn Journal of molecular modeling 2011 topics set
Sites and roles of phosphorylation of the human cytomegalovirus DNA polymerase subunit UL44. Laurie A Silva, Blair L Strang, Eric W Lin, Jeremy P Kamil, Donald M Coen Virology 2011 pols set
Identification of low-molecular weight inhibitors of HIV-1 reverse transcriptase using a cell-based high-throughput screening system. O Jegede, A Khodyakova, M Chernov, J Weber, L Menéndez-Arias, A Gudkov, ME Quiñones-Mateu Antiviral research 2011 pols set
The G157C mutation in the Escherichia coli sliding clamp specifically affects initiation of replication. Line Johnsen, Ingvild Flåtten, Morigen, Bjørn Dalhus, Magnar Bjørås, Torsten Waldminghaus, Kirsten Skarstad Molecular microbiology 2011 new
Role of a GAG hinge in the nucleotide-induced conformational change governing nucleotide specificity by T7 DNA polymerase. Zhinan Jin, Kenneth A Johnson The Journal of biological chemistry 2011 topics set
Interaction of gold nanoparticles with Pfu DNA polymerase and effect on polymerase chain reaction. L-P Sun, S Wang, Z-W Zhang, Y-Y Ma, Y-Q Lai, J Weng, Q-Q Zhang IET nanobiotechnology / IET 2011 pols set
Binding of Mn-deoxyribonucleoside triphosphates to the active site of the DNA polymerase of bacteriophage T7. Barak Akabayov, Charles C Richardson Powder diffraction 2011 new
ATR-mediated phosphorylation of DNA polymerase eta is needed for efficient recovery from UV damage. Thomas Göhler, Simone Sabbioneda, Catherine M Green, Alan R Lehmann J Cell Biol 2011 topics set
Links between DNA polymerase beta expression and sensitivity to bleomycin. Shukun Liu, Yanhao Lai, Wei Zhao, Mei Wu, Zhenzhong Zhang Toxicology 2011 topics set
In situ labeling of DNA breaks and apoptosis by T7 DNA polymerase. Vladimir V Didenko Methods in molecular biology (Clifton, N.J.) 2011 pols set
Roles of DNA polymerase I in leading and lagging-strand replication defined by a high-resolution mutation footprint of ColE1 plasmid replication. JM Allen, DM Simcha, NG Ericson, DL Alexander, JT Marquette, BP Van Biber, CJ Troll, R Karchin, JH Bielas, Lawrence A Loeb, Manel Camps Nucleic acids research 2011 topics set
Long-range PCR with a DNA polymerase fusion. Holly H Hogrefe, Michael C Borns Methods in molecular biology (Clifton, N.J.) 2011 topics set
DNA polymerase eta and chemotherapeutic agents. Kai-Ming Chou Antioxidants & redox signaling 2011 pols set
Protected immobilization of Taq DNA polymerase by active site masking on self-assembled monolayers of ω-functionalized thiols. Gumjung Lim, Hyun Jin Hwang, Jeong Hee Kim Analytical biochemistry 2011 pols set
How a DNA polymerase clamp loader opens a sliding clamp. Brian A Kelch, Debora L Makino, Mike E O'Donnell, John Kuriyan Science (New York, N.Y.) 2011 topics set
Pre-steady-state kinetic analysis of the incorporation of anti-HIV nucleotide analogs catalyzed by human X- and Y-family DNA polymerases. Jessica A Brown, Lindsey R Pack, Jason D Fowler, Zucai Suo Antimicrobial agents and chemotherapy 2011 new
Evaluation of the role of the vaccinia virus uracil DNA glycosylase and A20 proteins as intrinsic components of the DNA polymerase holoenzyme. Kathleen A Boyle, Eleni S Stanitsa, Matthew D Greseth, Jill K Lindgren, Paula Traktman The Journal of biological chemistry 2011 pols set
Mechanism of resistance to GS-9148 conferred by the Q151L mutation in HIV-1 reverse transcriptase. Brian J Scarth, Kirsten L White, James M Chen, Eric B Lansdon, S Swaminathan, Michael D Miller, Matthias Götte Antimicrobial agents and chemotherapy 2011 pols set
Nontemplate polymerization of free nucleotides into genetic elements by thermophilic DNA polymerase in vitro. Davis W Cheng, Alejandro Calderón-Urrea Nucleosides, nucleotides & nucleic acids 2011 new
Clustering of Alpers disease mutations and catalytic defects in biochemical variants reveal new features of molecular mechanism of the human mitochondrial replicase, Pol {gamma} Liliya Euro, Gregory A Farnum, Eino J H Palin, Anu Suomalainen, Laurie S Kaguni Nucleic acids research 2011 pols set
Micro-RNA quantification using DNA polymerase and pyrophosphate quantification. Hsiang-Ping Yu, Yi-Ling Hsiao, Hung-Yin Pan, Chih-Hung Huang, Shao-Yi Hou Analytical biochemistry 2011 new
The SMC-like protein complex SbcCD enhances DNA polymerase IV-dependent spontaneous mutation in Escherichia coli. Kimberly A M Storvik, Patricia L Foster J Bacteriol 2011 new
Family B DNA polymerase from a hyperthermophilic archaeon Pyrobaculum calidifontis: cloning, characterization and PCR application. Syed Farhat Ali, Naeem Rashid, Tadayuki Imanaka, Muhammad Akhtar Journal of bioscience and bioengineering 2011 new
Cloning and sequence analysis of novel DNA polymerases from thermophilic Geobacillus species isolated from hot springs in Turkey: characterization of a DNA polymerase I from Geobacillus kaue strain NB. Melike Çağlayan, Neş'e Bilgin Applied biochemistry and biotechnology 2011 new
Hsp12.6 expression is inducible by host immunity in adult worms of the parasitic nematode Nippostrongylus brasiliensis. Naoki Arizono, Masami Yamada, Tatsuya Tegoshi, Yutaka Takaoka, Mika Ohta, Toshiyuki Sakaeda PloS one 2011 new
[Genotypic resistance mutations to antiretroviral drugs in newly confirmed human immunodeficiency virus infectors in Beijing]. Jing-Rong Ye, Lei Guo, Hong-Yan Lu, Ruo-Lei Xin, Yi Zeng Zhonghua yi xue za zhi 2011 topics set
In Vitro Gap-directed Translesion DNA Synthesis of an Abasic Site Involving Human DNA Polymerases {epsilon}, {lambda}, and {beta}. Giuseppe Villani, Ulrich Hubscher, Nadege Gironis, Sinikka Parkkinen, Helmut Pospiech, Igor V Shevelev, Giulia di Cicco, Enni Markkanen, Juhani E Syväoja, Nicolas Tanguy Le Gac The Journal of biological chemistry 2011 new
The biochemistry and fidelity of synthesis by the apicoplast genome replication DNA polymerase Pfprex from the malaria parasite Plasmodium falciparum. Scott R Kennedy, Cheng-Yao Chen, Michael W Schmitt, Cole N Bower, Lawrence A Loeb Journal of molecular biology 2011 topics set
Hepatitis B Virus genotypic differences map structurally close to NRTI resistance hot spots. Eleftherios Michailidis, Kamlendra Singh, Karen A Kirby, Atsuko Hachiya, Wangdon Yoo, Sun Pyo Hong, Soo-Ok Kim, William R Folk, Stefan G Sarafianos International journal of current chemistry 2011 topics set
Crystal structure of SUMO-modified proliferating cell nuclear antigen. Bret D Freudenthal, John E Brogie, Lokesh Gakhar, Christine M Kondratick, M Todd Washington Journal of molecular biology 2011 new
Cytomegalovirus ileitis in a patient after liver transplantation-differentiating from de novo IBD. Udayakumar Navaneethan, Preethi G K Venkatesh, Jiang Wang Journal of Crohn's & colitis 2011 new
A simplified method for reconstituting active E. coli DNA polymerase III. Shi-Qiang Lin, Li-Jun Bi, Xian-En Zhang Protein & cell 2011 pols set
Fragment Screening and HIV Therapeutics. Joseph David Bauman, Disha Patel, Edward Arnold Topics in current chemistry 2011 pols set
Role of induced fit in limiting discrimination against AZT by HIV reverse transcriptase. Matthew W Kellinger, Kenneth A Johnson Biochemistry 2011 pols set
Induction of arginase II mRNA by nitric oxide using an in vitro model of gyrate atrophy of choroid and retina. Masayuki Ohnaka, Emiko Okuda-Ashitaka, Shiho Kaneko, Akira Ando, Masahide Maeda, Kyoji Furuta, Motoshi Suzuki, Kanji Takahashi, Seiji Ito Investigative ophthalmology & visual science 2011 new
Foamy retrovirus integrase contains a Pol dimerization domain required for protease activation. Eun-Gyung Lee, Jacqueline Roy, Dana Jackson, Patrick K Clark, Paul L Boyer, Stephen H Hughes, Maxine L Linial Journal of virology 2011 new
Yeast mitochondrial DNA polymerase is a highly processive single-subunit enzyme. Katrin Viikov, Priit Väljamäe, Juhan Sedman Mitochondrion 2011 complete Juhan Sedman*
N-3 Hydroxylation of Pyrimidine-2,4-diones Yields Dual Inhibitors of HIV Reverse Transcriptase and Integrase. Jing Tang, Kasthuraiah Maddali, Christine D Dreis, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang ACS medicinal chemistry letters 2011 pols set
P-glycoprotein substrate models using support vector machines based on a comprehensive data set. Zhengqiang Wang, Yuanying Chen, Hu Liang, Andreas Bender, Robert C Glen, Aixia Yan Journal of chemical information and modeling 2011 topics set
Changes in adiponectin expression in acute myocardial infarction rats and the significance of bisoprolol intervention. Song Zhang, Ben He, Steven Goldstein, Junbo Ge, Zhengqiang Wang, George Ruiz Canadian journal of physiology and pharmacology 2011 new
Dendrimers-delivered short hairpin RNA targeting hTERT inhibits oral cancer cell growth in vitro and in vivo. Xiqiang Liu, Hongzhang Huang, Jianguang Wang, Cheng Wang, Miao Wang, Bin Zhang, Chaobin Pan Biochemical pharmacology 2011 new
Reversible immortalization of rat pancreatic β cells with a novel immortalizing and tamoxifen-mediated self-recombination tricistronic vector. Hui-Ling Wu, Yu Wang, Peiming Zhang, Shu-Fa Li, Xiuping Chen, Yao-Kai Chen, Jun-Gang Li, Shi-Ming Yang, Yong-Ping Su, Jun-Ping Wang, Bing Chen Journal of biotechnology 2011 new
A novel DNA nuclease is stimulated by association with the GINS complex. Zhongjie Li, Miao Pan, Thomas J Santangelo, Wiebke Chemnitz, Wei Yuan, James L Edwards, Jerard Hurwitz, John N Reeve, Zvi Kelman Nucleic acids research 2011 new
Production of recombinant human DNA polymerase delta in a Bombyx mori bioreactor. Yanjiao Zhou, Huiqing Chen, Xincang Li, Yujue Wang, Keping Chen, Sufang Zhang, Xiao Meng, Ernest Y C Lee, Marietta Y W T Lee PloS one 2011 complete Yajing Zhou*
Molecular insights into DNA polymerase deterrents for ribonucleotide insertion. Nisha A Cavanaugh, William A Beard, Vinod K Batra, Lalith Perera, Lee G Pedersen, Samuel H Wilson The Journal of biological chemistry 2011 new
Backbone assignment of the little finger domain of a Y-family DNA polymerase. Dejian Ma, Jason D Fowler, Zucai Suo Biomolecular NMR assignments 2011 pols set
Rapid cell division contributes to efficient induction of A/T mutations during Ig gene hypermutation. Chie Kano, Rika Ouchida, Tetsuro Kokubo, Ji-Yang Wang Molecular immunology 2011 new
Photosensitized [2 + 2] cycloaddition of N-acetylated cytosine affords stereoselective formation of cyclobutane pyrimidine dimer. Junpei Yamamoto, Kosuke Nishiguchi, Koichiro Manabe, Chikahide Masutani, Fumio Hanaoka, Shigenori Iwai Nucleic acids research 2011 new
A Triad Interaction in the Fingers Subdomain of DNA Polymerase Beta Controls Polymerase Activity Joann B Sweasy, Joachim Jaeger, Drew L Murphy Journal of the American Chemical Society 2011 topics set
DNA replication and repair bypass machines. Ulrich Hübscher, Giovanni Maga Current opinion in chemical biology 2011 new
Human DNA Polymerase η Is Pre-Aligned for dNTP Binding and Catalysis. Ajay Ummat, Timothy D Silverstein, Rinku Jain, Angeliki Buku, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Journal of molecular biology 2011 topics set
Unlocking the sugar "steric gate" of DNA polymerases. Jessica A Brown, Zucai Suo Biochemistry 2011 new
6-Benzoyl-3-hydroxypyrimidine-2,4-diones as dual inhibitors of HIV reverse transcriptase and integrase. Jing Tang, Kasthuraiah Maddali, Christine D Dreis, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang Bioorganic & medicinal chemistry letters 2011 pols set
Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures. Shuangluo Xia, Michael Wang, Harold R Lee, Arjun Sinha, Gregor Blaha, Thomas David Christian, Jianhong Wang, William H Konigsberg Journal of molecular biology 2011 topics set
Pyrovanadolysis, a Pyrophosphorolysis-like Reaction Mediated by Pyrovanadate, Mn2+, and DNA Polymerase of Bacteriophage T7. Barak Akabayov, Arkadiusz W Kulczyk, Sabine R Akabayov, Christopher Theile, Larry W McLaughlin, Benjamin Beauchamp, Antoine M van Oijen, Charles C Richardson The Journal of biological chemistry 2011 new
K70Q adds high-level tenofovir resistance to "Q151M complex" HIV reverse transcriptase through the enhanced discrimination mechanism. Atsuko Hachiya, Eiichi N Kodama, Matthew M Schuckmann, Karen A Kirby, Eleftherios Michailidis, Yasuko Sakagami, Shinichi Oka, Kamalendra Singh, Stefan G Sarafianos PloS one 2011 pols set
Architecture of the DNA polymerase B-proliferating cell nuclear antigen (PCNA)-DNA ternary complex. Kouta Mayanagi, Shinichi Kiyonari, Hirokazu Nishida, Mihoko Saito, Daisuke Kohda, Yoshizumi Ishino, Tsuyoshi Shirai, Kosuke Morikawa Proceedings of the National Academy of Sciences of the United States of America 2011 new
Replication infidelity via a mismatch with Watson-Crick geometry. Katarzyna Bebenek, Lars C Pedersen, Thomas A Kunkel Proceedings of the National Academy of Sciences of the United States of America 2011 topics set
Unexpected role for Helicobacter pylori DNA polymerase I as a source of genetic variability. María-Victoria García-Ortíz, Stéphanie Marsin, Mercedes E Arana, Didier Gasparutto, Raphaël Guérois, Thomas A Kunkel, J Pablo Radicella PLoS genetics 2011 complete J Pablo Radicella*
Novel role of base excision repair (BER) in mediating cisplatin cytotoxicity. Anbarasi Kothandapani, Venkata Srinivas Mohan Nimai Dangeti, Ashley R Brown, Lauren A Banze, Xiao-Hong Wang, Robert W Sobol, Steve M Patrick The Journal of biological chemistry 2011 topics set
[Effects of DNA polymerase beta on the genotoxicity and genetic instability induced by benzo(a)pyrene]. Mo Yang, Mei Wu, Jie Cui, Chen Chen, Zun-zhen Zhang Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 2011 new
Substrate mimicry: HIV-1 reverse transcriptase recognizes 6-modified-3'-azido-2',3'-dideoxyguanosine-5'-triphosphates as adenosine analogs. Brian D Herman, Raymond F Schinazi, Hong-Wang Zhang, James H Nettles, Richard Stanton, Mervi Detorio, Aleksandr Obikhod, Ugo Pradère, Steven J Coats, John W Mellors, Nicolas Sluis-Cremer Nucleic acids research 2011 topics set
Sequence Quality Analysis Tool (SQUAT) for HIV-1 Protease and Reverse Transcriptase. Allison K Delong, Mingham Wu, Diane Bennett, Neil Parkin, Zhijin Wu, Joseph W Hogan, Rami Kantor AIDS research and human retroviruses 2011 pols set
[Effects of cerebellar fastigial nucleus electrical stimulation on telomerase reverse transcriptase expression and mitochondrial apoptotic pathway in rats with focal cerebral ischemia and reperfusion]. Yi Yang, Jing-Li Liu, Chao Qin, Jin-Pin Li, Xiao-Ling Wang, Zhao-Xia Zhang, Linqi Zhang Zhonghua yi xue za zhi 2011 topics set
Biochemical, inhibition and inhibitor resistance studies of xenotropic murine leukemia virus-related virus reverse transcriptase. Tanyaradzwa P Ndongwe, Adeyemi O Adedeji, Eleftherios Michailidis, Yee Tsuey Ong, Atsuko Hachiya, Bruno Marchand, Emily M Ryan, Devendra K Rai, Karen A Kirby, Angela S Whatley, Donald H Burke, Marc Johnson, Shilei Ding, Yi-Min Zheng, Shan-Lu Liu, Ei-Ichi Kodama, Krista A Delviks-Frankenberry, Vinay K Pathak, Hiroyuki Mitsuya, Michael A. Parniak, Kamalendra Singh, Stefan G Sarafianos Nucleic acids research 2011 pols set
Human telomerase reverse transcriptase regulates cyclin D1 and G1/S phase transition in laryngeal squamous carcinoma. Jinming Li, Xinsheng Huang, Xiaofeng Xie, Jianzhong Wang, Maoli Duan Acta oto-laryngologica 2011 new
Role of high-fidelity Escherichia coli DNA polymerase I in replication bypass of a deoxyadenosine DNA-peptide cross-link. Kinrin Yamanaka, Irina G Minko, Steven E Finkel, Myron F Goodman, R Stephen Lloyd Journal of bacteriology 2011 new
Effect of the Y955C mutation on mitochondrial DNA polymerase nucleotide incorporation efficiency and fidelity. Patricia A Estep, Kenneth A Johnson Biochemistry 2011 new
Biochemical analysis of the G517V POLG variant reveals wild-type like activity. Rajesh Kasiviswanathan, William C Copeland Mitochondrion 2011 new
Ribonucleotide discrimination and reverse transcription by the human mitochondrial DNA polymerase. Rajesh Kasiviswanathan, William C Copeland The Journal of biological chemistry 2011 new
Inhibitory effect of novel 5-O-acyl juglones on mammalian DNA polymerase activity, cancer cell growth and inflammatory response. Sayako Maruo, Isoko Kuriyama, Kouji Kuramochi, Kazunori Tsubaki, Hiromi Yoshida, Yoshiyuki Mizushina Bioorganic & medicinal chemistry 2011 new
Inhibitory effects of vitamin K3 derivatives on DNA polymerase and inflammatory activity. Aoganghua Aoganghua, Shin Nishiumi, Kazuki Kobayashi, Masayuki Nishida, Kouji Kuramochi, Kazunori Tsubaki, Midori Hirai, Shinwa Tanaka, Takeshi Azuma, Hiromi Yoshida, Yoshiyuki Mizushina, Masaru Yoshida International journal of molecular medicine 2011 new
Effects of Intermediates between Vitamins K(2) and K(3) on Mammalian DNA Polymerase Inhibition and Anti-Inflammatory Activity. Yoshiyuki Mizushina, Jun Maeda, Yasuhiro Irino, Masayuki Nishida, Shin Nishiumi, Yasuyuki Kondo, Kazuyuki Nishio, Kouji Kuramochi, Kazunori Tsubaki, Isoko Kuriyama, Takeshi Azuma, Hiromi Yoshida, Masaru Yoshida International journal of molecular sciences 2011 pols set
Anti-cancer effect of spinach glycoglycerolipids as angiogenesis inhibitors based on the selective inhibition of DNA polymerase activity. Naoki Maeda, Kiminori Matsubara, Hiromi Yoshida, Yoshiyuki Mizushina Mini reviews in medicinal chemistry 2011 new
[Exploration of relationship between the expression level of DNA polymerase beta and 60Co gamma-ray radiosensitivity]. Jie Cui, Xin Xu, Mo Yang, Chen Chen, Wei Zhao, Mei Wu, Zun-zhen Zhang Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 2011 new
[Effect of DNA polymerase beta on apoptosis and mitochondrial membrane potential induced by hydroquinone, a metabolite of benzene]. Chen Chen, Mo Yang, Zun-zhen Zhang, Mei Wu, Wen-wen Deng Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 2011 pols set
Ddc1 checkpoint protein and DNA polymerase ɛ interact with nick-containing DNA repair intermediate in cell free extracts of Saccharomyces cerevisiae. Maria V Sukhanova, Claudine D'Herin, Patricia Auffret van der Kemp, Vladimir V Koval, Serge Boiteux, Olga I Lavrik DNA repair 2011 new
Polymerase Chaperoning and Multiple ATPase Sites Enable the E. coli DNA Polymerase III Holoenzyme to Rapidly Form Initiation Complexes. Christopher D Downey, Elliott Crooke, Charles S McHenry Journal of molecular biology 2011 pols set
Broad-spectrum aptamer inhibitors of HIV reverse transcriptase closely mimic natural substrates. Mark A Ditzler, Debojit Bose, Nikolozi Shkriabai, Bruno Marchand, Stefan G Sarafianos, Mamuka Kvaratskhelia, Donald H Burke Nucleic acids research 2011 pols set
AP-site cleavage activity of tyrosyl-DNA phosphodiesterase 1. Natalia A Lebedeva, Nadejda I Rechkunova, Olga I Lavrik FEBS letters 2011 new
1,N2-Etheno-2'-deoxyguanosine adopts the syn conformation about the glycosyl bond when mismatched with deoxyadenosine. Ganesh Shanmugam, Ivan D Kozekov, F Peter Guengerich, Carmelo J Rizzo, Michael P Stone Chemical research in toxicology 2011 new
Cloning, expression, and PCR application of DNA polymerase from the hyperthermophilic archaeon, Thermococcus celer. Kee Pum Kim, Heejin Bae, In Hye Kim, Suk-Tae Kwon Biotechnol Lett 2011 topics set
Roles of the Four DNA Polymerases of the Crenarchaeon Sulfolobus solfataricus and Accessory Proteins in DNA Replication. Jeong-Yun Choi, Robert Lawton Eoff, Matthew G Pence, Jian Wang, Martha V Martin, Eun-Jin Kim, Lindsay M Folkmann, F Peter Guengerich The Journal of biological chemistry 2011 new
Efficiency and fidelity of human DNA polymerases λ and β during gap-filling DNA synthesis. Jessica A Brown, Lindsey R Pack, Laura E Sanman, Zucai Suo DNA repair 2011 new
Quantitative analysis of the efficiency and mutagenic spectra of abasic lesion bypass catalyzed by human Y-family DNA polymerases. Shanen M Sherrer, Kevin A Fiala, Jason D Fowler, Sean A Newmister, John M Pryor, Zucai Suo Nucleic acids research 2011 new
Enantioselective binding of second generation pyrrolobenzoxazepinones to the catalytic ternary complex of HIV-1 RT wild-type and L100I and K103N drug resistant mutants. Stefania Butini, Sandra Gemma, Margherita Brindisi, Giuseppe Borrelli, Isabella Fiorini, Alberta Samuele, Aristotele Karytinos, Marcella Facchini, Andrea Lossani, Samantha Zanoli, Giuseppe Campiani, Ettore Novellino, Federico Focher, Giovanni Maga Bioorganic & medicinal chemistry letters 2011 pols set
Structure of a preternary complex involving a prokaryotic NHEJ DNA polymerase. Nigel C Brissett, Maria Jose Martin, Robert S Pitcher, Julie Bianchi, Raquel Juarez, Andrew J Green, Gavin C Fox, Luis Blanco, Aidan J Doherty Molecular cell 2011 topics set
Indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: new cyclic substituents at indole-2-carboxamide. Giuseppe La Regina, Antonio Coluccia, Andrea Brancale, Francesco Piscitelli, Valerio Gatti, Giovanni Maga, Alberta Samuele, Christophe Pannecouque, Dominique Schols, Jan Balzarini, Ettore Novellino, Romano Silvestri Journal of medicinal chemistry 2011 pols set
Mitochondrial DNA replication and disease: insights from DNA polymerase gamma mutations. Jeffrey D Stumpf, William C Copeland Cell Mol Life Sci 2011 new
Site-directed mutagenesis of the χ subunit of DNA polymerase III and single-stranded DNA-binding protein of E. coli reveals key residues for their interaction. Natalie Naue, Roman Fedorov, Andreas Pich, Dietmar J Manstein, Ute Curth Nucleic acids research 2011 pols set
Crystal structure of tert-butyldimethylsilyl-spiroaminooxathioledioxide-thymine (TSAO-T) in complex with HIV-1 reverse transcriptase (RT) redefines the elastic limits of the non-nucleoside inhibitor-binding pocket. Kalyan Das, Joseph David Bauman, Angela S Rim, Chhaya Dharia, Arthur D Clark, María-José Camarasa, Jan Balzarini, Edward Arnold Journal of medicinal chemistry 2011 complete Kalyan Das*
Recent advances in DAPYs and related analogues as HIV-1 NNRTIs. Xuwang Chen, Peng Zhan, Dongyue Li, Erik De Clercq, Xinyong Liu Current medicinal chemistry 2011 pols set
Learning from Directed Evolution: Thermus aquaticus DNA Polymerase Mutants with Translesion Synthesis Activity. Samra Obeid, Andreas Schnur, Christian Gloeckner, Nina Blatter, Wolfram Welte, Kay Diederichs, Andreas Marx Chembiochem : a European journal of chemical biology 2011 complete Andreas Marx*
[Screening program on novel drug resistance mutations of subtype B' in human immunodeficiency virus type 1 in China.] Han-Ping Li, Wei Guo, Yong-Jian Liu, Zuo-Yi Bao, Lin Li, Dao-Min Zhuang, Si-Yang Liu, Zhengqiang Wang, Xiao-Lin Wang, Jing-Yun Li Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 2011 pols set
Comparison of two POLQ mutants reveals that a polymerase-inactive POLQ retains significant function in tolerance to etoposide and γ-irradiation in mouse B cells. Yingqian Li, Xiang Gao, Ji-Yang Wang Genes to cells : devoted to molecular & cellular mechanisms 2011 new
Mitochondrial DNA polymerase {gamma} mutations: an ever expanding molecular and clinical spectrum. Sha Tang, Jing Wang, Ni-Chung Lee, Margherita Milone, Michelle C Halberg, Eric S Schmitt, William J Craigen, Weiming Zhang, Lee-Jun C Wong Journal of medical genetics 2011 new
HIV-1 NNRTIs: Structural diversity, pharmacophore similarity, and implications for drug design. Peng Zhan, Xuwang Chen, Dongyue Li, Zengjun Fang, Erik De Clercq, Xinyong Liu Medicinal research reviews 2011 pols set
The effect of aging on the DNA damage and repair capacity in 2BS cells undergoing oxidative stress. Jin-Ling Wang, Pei-Chang Wang Molecular biology reports 2011 new
Synthesis and biological evaluation of novel 5-alkyl-2-arylthio-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. Jing Zhang, Peng Zhan, Jingde Wu, Zhongjie Li, Yan Jiang, Weiying Ge, Christophe Pannecouque, Erik De Clercq, Xinyong Liu Bioorganic & medicinal chemistry 2011 pols set
Increased Platelet Reactivity in HIV-1-Infected Patients Receiving Abacavir-Containing Antiretroviral Therapy. Claudette S Satchell, Jane A O'Halloran, Aoife G Cotter, Aaron J Peace, Eileen F O'Connor, Anthony F Tedesco, Eoin R Feeney, John S Lambert, Gerard J Sheehan, Dermot Kenny, Patrick W G Mallon The Journal of infectious diseases 2011 topics set
hTERT promoter methylation and telomere length in childhood acute lymphoblastic leukemia - associations with immunophenotype and cytogenetic subgroup. M Borssen, I Cullman, U Noren-Nystrom, C Sundstrom, A Porwit, E Forestier, G Roos Experimental hematology 2011 topics set
DNA polymerase ι of mammals as a participant in translesion synthesis of DNA. Leonid V Gening Biochemistry. Biokhimii͡a 2011 topics set
DNA polymerase activity at the single-molecule level. JP Gill, J Wang, David P Millar Biochemical Society transactions 2011 new
3-Hydroxypyrimidine-2,4-diones as an inhibitor scaffold of HIV integrase. Jing Tang, Kasthuraiah Maddali, Mathieu Metifiot, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang Journal of medicinal chemistry 2011 pols set
The high fidelity and unique error signature of human DNA polymerase epsilon. Dagmara A Korona, Kimberly G Lecompte, Zachary F Pursell Nucleic acids research 2011 topics set
Whole-genome amplification using Φ29 DNA polymerase. Noël P Burtt Cold Spring Harbor protocols 2011 pols set
Diarylpyrimidine-dihydrobenzyloxopyrimidine hybrids: new, wide-spectrum anti-HIV-1 agents active at (sub)-nanomolar level. Dante Rotili, Domenico Tarantino, Marino Artico, Maxim B Nawrozkij, Emmanuel Gonzalez-Ortega, B Clotet, Alberta Samuele, José A Esté, Giovanni Maga, Antonello Mai Journal of medicinal chemistry 2011 pols set
One-year monthly survey of rotavirus, astrovirus and norovirus in three sewage treatment plants in Beijing, China and associated health risk assessment. Xiao Q He, Li Cheng, D Y Zhang, Xiang M Xie, D H Wang, Zhengqiang Wang Water science and technology : a journal of the International Association on Water Pollution Research 2011 new
Tumor-specific expression of microRNA-26a suppresses human hepatocellular carcinoma growth via cyclin-dependent and -independent pathways. Lizao Chen, Jianming Zheng, Yongqing Zhang, Luxi Yang, Jiaqi Wang, Jian Ni, Daxiang Cui, Chaoqin Yu, Zailong Cai Molecular therapy : the journal of the American Society of Gene Therapy 2011 new
Characterization of marine X-family DNA polymerases and comparative analysis of base excision repair proteins. Hirofumi Kodera, Ryo Takeuchi, Yukinobu Uchiyama, Yoichi Takakusagi, Kazuki Iwabata, Hidetsugu Miwa, Naoto Hanzawa, Fumio Sugawara, Kengo Sakaguchi Biochemical and biophysical research communications 2011 topics set
Identification and expression of a putative LPS-induced TNF-α factor from Asiatic hard clam Meretrix meretrix. Hong-Jun Li, Qing Yang, Xiang-Gang Gao, Hao Su, Juan Wang, Chong-Bo He Molecular biology reports 2011 new
Screening and identification of specific markers for bladder transitional cell carcinoma from urine urothelial cells with suppressive subtractive hybridization and cDNA microarray. Baihong Guo, Tuanjie Che, Baoguang Shi, Lijun Guo, Yongsheng Yin, Lin Li, Jinming Wang, Dongwen Yan, Yirong Chen Canadian Urological Association journal = Journal de l'Association des urologues du Canada 2011 new
Ultra-sensitive DNA assay based on single-molecule detection coupled with fluorescent quantum dot-labeling and its application to determination of messenger RNA. Li Li, Xincang Li, Lu Li, Jinxing Wang, Wenrui Jin Analytica chimica acta 2011 new
Insights into Base Selectivity from the 1.8 A Resolution Structure of an RB69 DNA Polymerase Ternary Complex. Michael Wang, Shuangluo Xia, Gregor Blaha, Thomas A Steitz, William H Konigsberg, Jianhong Wang Biochemistry 2011 topics set
Structure of the 2-Aminopurine-Cytosine Base Pair Formed in the Polymerase Active Site of the RB69 Y567A-DNA Polymerase. Linda J Reha-Krantz, Chithra Hariharan, Usharani Subuddhi, Shuangluo Xia, Chao Zhao, Jeffrey Beckman, Thomas David Christian, William H Konigsberg Biochemistry 2011 topics set
Characterization of the elongation complex of dengue virus RNA polymerase: assembly, kinetics of nucleotide incorporation, and fidelity. Zhinan Jin, Jerome Deval, Kenneth A Johnson, David C Swinney The Journal of biological chemistry 2011 pols set
Effects of quinone derivatives, such as 1,4-naphthoquinone, on DNA polymerase inhibition and anti-inflammatory action. Kazuki Kobayashi, Shin Nishiumi, Masayuki Nishida, Midori Hirai, Takeshi Azuma, Hiromi Yoshida, Yoshiyuki Mizushina, Masaru Yoshida Medicinal chemistry (Shāriqah (United Arab Emirates)) 2011 topics set
Drug-sensitive DNA Polymerase {delta} Reveals a Role for Mismatch Repair in Checkpoint Activation in Yeast. Linda J Reha-Krantz, Md Shahjahan P Siddique, Kelly M Murphy, Andrea Tam, Michelle O'Carroll, Sam Lou, Amy Schultz, Charles Boone Genetics 2011 pols set
Metal-induced DNA translocation leads to DNA polymerase conformational activation. Thomas W Kirby, Eugene F DeRose, Nisha A Cavanaugh, William A Beard, David D Shock, Geoffrey A Mueller, Samuel H Wilson, Robert E London Nucleic acids research 2011 new
Structural Insights into Complete Metal Ion Coordination from Ternary Complexes of B Family RB69 DNA Polymerase. Shuangluo Xia, Michael Wang, Gregor Blaha, William H Konigsberg, Jianhong Wang Biochemistry 2011 pols set
[The prevalence of HIV-1 drug resistance and associated factors in AIDS patients receiving HAART in Zhecheng county, Henan province]. Yuan Yuan, Hui Xing, Xiao-Yu Wang, Chun-hua Liu, Li-Ting Yang, Ben-Feng Zheng, Xia Wang, Yu-Hua Ruan, Zhe Wang, Hong-wei Liu, Yi-ming Shao Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 2011 pols set
Dehydroaltenusin is a specific inhibitor of mammalian DNA polymerase α Yoshiyuki Mizushina, Naoki Maeda, Isoko Kuriyama, Hiromi Yoshida Expert opinion on investigational drugs 2011 topics set
REV1 and polymerase {zeta} facilitate homologous recombination repair. S Sharma, JK Hicks, CL Chute, JR Brennan, JY Ahn, TW Glover, CE Canman Nucleic acids research 2011 topics set
A functional tandem-repeats polymorphism in the downstream of TERT is associated with the risk of nasopharyngeal carcinoma in Chinese population. Yang Zhang, Hongxing Zhang, Yun Zhai, Zhifu Wang, Fuchao Ma, Hongxue Wang, Peiyao Li, Ying Zhang, Lixia Yu, Ying Cui, Fuchu He, Gangqiao Zhou BMC medicine 2011 topics set
Nucleosome Disruption by DNA Ligase III-XRCC1 Promotes Efficient Base Excision Repair. Ian D Odell, Joy-El Barbour, Drew L Murphy, Julie A Della Maria, Joann B Sweasy, Alan E Tomkinson, Susan S Wallace, David S Pederson Molecular and cellular biology 2011 complete David S Pederson*
Antimutator alleles of yeast DNA polymerase gamma modulate the balance between DNA synthesis and excision. Françoise Foury, Karolina Szczepanowska PloS one 2011 topics set
The sugar ring conformation of 4'-ethynyl-2-fluoro-2'-deoxyadenosine and its recognition by the polymerase active site of HIV reverse transcriptase. Karen A Kirby, Kamalendra Singh, Eleftherios Michailidis, Bruno Marchand, Eiichi N Kodama, Noriyuki Ashida, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos Cellular and molecular biology (Noisy-le-Grand, France) 2011 pols set
Non-nucleosidic inhibition of Herpes simplex virus DNA polymerase: mechanistic insights into the anti-herpetic mode of action of herbal drug withaferin A. Abhinav Grover, Vibhuti Agrawal, Ashutosh Shandilya, Virendra S Bisaria, Durai Sundar BMC bioinformatics 2011 topics set
Characterization of family IV UDG from Aeropyrum pernix and its application in hot-start PCR by family B DNA polymerase. Xi-Peng Liu, Jian-Hua Liu PloS one 2011 topics set
Bypass of a nick by the replisome of bacteriophage T7. B Zhu, Seung-Joo Lee, Charles C Richardson The Journal of biological chemistry 2011 complete Charles C Richardson*, Bin Zhu*
Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates. Dimitri Topalis, Ugo Pradère, Vincent Roy, Christophe Caillat, Ahmed Azzouzi, Julie Broggi, Robert Snoeck, Graciela Andrei, Jay Lin, Staffan Eriksson, Julie A C Alexandre, Chahrazade El-Amri, Dominique Deville-Bonne, Philippe Meyer, Jan Balzarini, Luigi A Agrofoglio Journal of medicinal chemistry 2011 new
Selective inhibition of Human Immunodeficiency Virus type 1 (HIV-1) by a novel family of tricyclic nucleosides. María-Cruz Bonache, Alessandra Cordeiro, Ernesto Quesada, Els Vanstreels, Dirk Daelemans, María-José Camarasa, Jan Balzarini, Ana San-Félix Antiviral research 2011 pols set
Mitochondrial disorders of DNA polymerase γ dysfunction: from anatomic to molecular pathology diagnosis. Linsheng Zhang, Sherine S L Chan, Daynna J Wolff Archives of pathology & laboratory medicine 2011 new
Loop-mediated isothermal amplification: rapid detection of Angiostrongylus cantonensis infection in Pomacea canaliculata. Rui Chen, QunBo Tong, Yongqing Zhang, Di Lou, QingMing Kong, Shan Lv, MingMing Zhuo, LiYong Wen, ShaoHong Lu Parasites & vectors 2011 new
Review of QSAR for DNA polymerase inhibitors and new models for heterogeneous series of compounds. Isela García, Yagamare Fall, Generosa Gómez Current computer-aided drug design 2011 new
[Identification the relationship between mutation patterns of rtM204I/V in the polymerase gene and genotypes of hepatitis B virus]. Li Yan, Lei Xiao, Jun-Feng Wei, Jian Sun, Zhan-hui Wang, Jin-lin Hou Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 2011 pols set
Mitochondrial DNA polymerase editing mutation, PolgD257A, reduces the diabetic phenotype of Akita male mice by suppressing appetite. R Fox, HS Kim, RL Reddick, Greg C Kujoth, Tomas A Prolla, S Tsutsumi, Y Wada, O Smithies, Naoki Maeda Proceedings of the National Academy of Sciences of the United States of America 2011 pols set
Lesion bypass activity of DNA polymerase theta (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts. Matthew Hogg, Masayuki Seki, Richard D Wood, Sylvie Doublié, Susan S Wallace Journal of molecular biology 2011 new
dnaX36 Mutator of Escherichia coli: effects of the {tau} subunit of the DNA polymerase III holoenzyme on chromosomal DNA replication fidelity. Damian Gawel, Piotr Jonczyk, I Fijalkowska, Roel M Schaaper J Bacteriol 2011 new
Improved thermostability and PCR efficiency of Thermococcus celericrescens DNA polymerase via site-directed mutagenesis. Kee Pum Kim, Sung Suk Cho, Kang Keun Lee, Man Hui Youn, Suk-Tae Kwon Journal of biotechnology 2011 new
Mechanism of interaction of novel indolylarylsulfone derivatives with K103N and Y181I mutant HIV-1 reverse transcriptase in complex with its substrates. Alberta Samuele, Sara Bisi, Alexandra Kataropoulou, Giuseppe La Regina, Francesco Piscitelli, Valerio Gatti, Romano Silvestri, Giovanni Maga Antiviral chemistry & chemotherapy 2011 pols set
Pirh2 E3 ubiquitin ligase monoubiquitinates DNA polymerase eta to suppress translesion DNA synthesis. Yong-Sam Jung, Anne Hakem, Razqallah Hakem, Xinbin Chen Molecular and cellular biology 2011 new
The Y-family DNA polymerase Dpo4 uses a template slippage mechanism to create single-base deletions. Yifeng Wu, Ryan C Wilson, Janice D Pata Journal of bacteriology 2011 new
Liver-specific gene therapy of hepatocellular carcinoma by targeting human telomerase reverse transcriptase with pegylated immuno-lipopolyplexes. Yurong Hu, Yingying Shen, Baofang Ji, Shasha Yin, Xueling Ren, Tingting Chen, Yue Ma, Zhenzhong Zhang, Yongqing Zhang European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2011 new
Combinational RNAi gene therapy of hepatocellular carcinoma by targeting human EGFR and TERT. Yurong Hu, Yingying Shen, Baofang Ji, Lei Wang, Zhenzhong Zhang, Yongqing Zhang European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2011 new
Analysis of differential gene expression by bead-based fiber-optic array in nonfunctioning pituitary adenomas. Zhiquan Jiang, Songbo Gui, Yongqing Zhang Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2011 new
Recombinant adenovirus-mediated human telomerase reverse transcriptase gene can stimulate cell proliferation and maintain primitive characteristics in bovine mammary gland epithelial cells. Xiao-Ying He, Yue-Mao Zheng, Jie Lan, Yue-Hong Wu, Jing Yan, Xiao-Ning He, Tuo Zhang, Yu-Long He, Yan-Ling Zheng, Yongqing Zhang Development, growth & differentiation 2011 new
Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China. Tao Dong, Yongqing Zhang, Ke Yi Xu, Huiping Yan, Ian James, Yanchun Peng, Marie-Eve Blais, Silvana Gaudieri, Xinyue Chen, Wenhui Lun, Hao Wu, Wen Yan Qu, Tim Rostron, Ning Li, Yu Mao, Simon Mallal, Xiaoning Xu, Andrew McMichael, Mina John, Sarah L Rowland-Jones Blood 2011 pols set
Co-expression of herpes simplex virus thymidine kinase and Escherichia coli nitroreductase by an hTERT-driven adenovirus vector in breast cancer cells results in additive anti-tumor effects. Bin Yu, Yongqing Zhang, Yang Zhan, Xiao Zha, Yonege Wu, Xizhen Zhang, Qingzhe Dong, Wei Kong, Xianghui Yu Oncology reports 2011 new
Analysis of differential gene expression using fiber-optic bead array and pathway analyses in pituitary adenomas. Zhiquan Jiang, Songbo Gui, Yongqing Zhang Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2011 new
Knockdown of hTERT alters biophysical properties of K562 cells resulting in decreased migration rate in vitro. Yongqing Zhang, Xiaopeng Chen, Xiaofeng Xu, Xianwei Wang, Xifu Wang, Guihong Yuan, Dagong Sun, Weibo Ka, Dongqi He, Zongyao Wen, Weijuan Yao Cell biochemistry and biophysics 2011 new
Detection of lamivudine- or adefovir-resistant hepatitis B virus mutations by a liquid array. Hongyan Liu, Richeng Mao, Lili Fan, Jiahui Xia, Yiliang Li, Yongxi Yin, Xincang Li, Xu Zhao, Hongying Guo, Haoxiang Zhu, Yongqing Zhang, Yaoyue Kang, Jiming Zhang Journal of virological methods 2011 new
Effect of plasmid-mediated RNA interference targeting telomerase reverse transcriptase on lung cancer cells. Linhu Ge, Zhansheng Deng, Yongqing Zhang, Wenlong Shao, Yuan Qiu, Dong Cui, Donghai Huang Oncology reports 2011 new
Structure of the SSB-DNA polymerase III interface and its role in DNA replication. Aimee H Marceau, Soon Bahng, Shawn C Massoni, Nicholas P George, Steven J Sandler, Kenneth J Marians, James L Keck The EMBO journal 2011 new
PCNA binding domains in all three subunits of yeast DNA polymerase {delta} modulate its function in DNA replication. Narottam Acharya, Roland Klassen, Robert E Johnson, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2011 topics set
The Mechanism of Interaction of Human Mitochondrial DNA Polymerase γ with the Novel Nucleoside Reverse Transcriptase Inhibitor 4' -Ethynyl-2-Fluoro-2' -Deoxyadenosine Indicates a Low Potential for Host Toxicity. Christal D Sohl, Kamlendra Singh, Rajesh Kasiviswanathan, William C Copeland, Hiroyuki Mitsuya, Stefan G Sarafianos, Karen S Anderson Antimicrobial agents and chemotherapy 2011 new
Polbase: a repository of biochemical, genetic and structural information about DNA polymerases. BW Langhorst, William E Jack, L Reha-Krantz, NM Nichols Nucleic acids research 2011 complete Brad Langhorst*
Human Cytomegalovirus UL44 Concentrates at the Periphery of Replication Compartments, the Site of Viral DNA Synthesis. Blair L Strang, Steeve Boulant, Lynne Chang, David M Knipe, Tomas Kirchhausen, Donald M Coen Journal of virology 2011 new
Interaction of HIV-1 reverse transcriptase ribonuclease H with an acylhydrazone inhibitor. Qingguo Gong, Lakshmi Menon, Tatiana Ilina, Lena G Miller, Jinwoo Ahn, Michael A. Parniak, Rieko Ishima Chemical biology & drug design 2011 pols set
Long patch base excision repair compensates for DNA polymerase β inactivation by the C4'-oxidized abasic site. Aaron C Jacobs, Cortney R Kreller, Marc M Greenberg Biochemistry 2011 topics set
Characterization of the χψ subcomplex of Pseudomonas aeruginosa DNA polymerase III. Sirine El Houry Mignan, Gregor Witte, Natalie Naue, Ute Curth BMC molecular biology 2011 topics set
Kinetic analysis of the unique error signature of human DNA polymerase ν Mercedes E Arana, Olga Potapova, Thomas A Kunkel, Catherine M Joyce Biochemistry 2011 topics set
Kinetic Mechanism of Active Site Assembly and Chemical Catalysis of DNA Polymerase β PB Balbo, EC Wang, MD Tsai Biochemistry 2011 topics set
A template-dependent dislocation mechanism potentiates K65R reverse transcriptase mutation development in subtype C variants of HIV-1. Dimitrios Coutsinos, Cédric F Invernizzi, Daniela D Moisi, Maureen Oliveira, Jorge L Martinez-Cajas, Bluma G Brenner, Mark A. Wainberg PloS one 2011 pols set
Phosphorylation of the p68 Subunit of Pol δ Acts as a Molecular Switch to Regulate Its Interaction with PCNA. Amal A Rahmeh, Yajing Zhou, Bin Xie, Hao Li, Ernest Y C Lee, Marietta Y W T Lee Biochemistry 2011 new
The DNA polymerase activity of Saccharomyces cerevisiae Rev1 is biologically significant. Mary Ellen Wiltrout, Graham C Walker Genetics 2011 pols set
Relaxed complex scheme suggests novel inhibitors for the lyase activity of DNA polymerase beta. Khaled H Barakat, Jack A Tuszynski Journal of molecular graphics & modelling 2011 topics set
Enzymatic assembly of overlapping DNA fragments. Daniel G Gibson Methods in enzymology 2011 topics set
Distinct roles of the active-site Mg2+ ligands, Asp882 and Asp705, of DNA polymerase I (Klenow fragment) during the prechemistry conformational transitions. Oya Bermek, Nigel D F Grindley, Catherine M Joyce The Journal of biological chemistry 2011 topics set
White spot syndrome virus Orf514 encodes a bona fide DNA polymerase. Enrique de-la-Re-Vega, Karina D Garcia-Orozco, Aldo A Arvizu-Flores, Gloria Yepiz-Plascencia, Adriana Muhlia-Almazan, Jesús Hernández, Luis G Brieba, Rogerio R Sotelo-Mundo Molecules (Basel, Switzerland) 2011 topics set
The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an ajar intermediate conformation in the nucleotide selection mechanism E Wu, L Beese The Journal of biological chemistry 2011 topics set
USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA polymerase β. Jason L Parsons, Irina I Dianova, Svetlana V Khoronenkova, Mariola J Edelmann, Benedikt M Kessler, Grigory L Dianov Molecular cell 2011 topics set
Evolution of full-length HBV sequences in chronic hepatitis B patients with sequential lamivudine and adefovir dipivoxil resistance. Chien-Hung Chen, Chuan-Mo Lee, Wei-Chih Tung, Jing-Houng Wang, Chao-Hung Hung, Tsung-Hui Hu, Jyh-Chwan Wang, Sheng-Nan Lu, Chi-Sin Changchien Journal of hepatology 2010 new
Mutator phenotypes due to DNA replication infidelity. Mercedes E Arana, Thomas A Kunkel Seminars in cancer biology 2010 new
Synthesis and biological evaluation of 4-(hydroxyimino)arylmethyl diarylpyrimidine analogues as potential non-nucleoside reverse transcriptase inhibitors against HIV. Xiao-Qing Feng, Zhao-Sen Zeng, Yong-Hong Liang, Fen-Er Chen, Christophe Pannecouque, Jan Balzarini, Erik De Clercq Bioorganic & medicinal chemistry 2010 new
Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange. Bret D Freudenthal, Lokesh Gakhar, S Ramaswamy, M Todd Washington Nature structural & molecular biology 2010 new
Nucleotide-dependent conformational change governs specificity and analog discrimination by HIV reverse transcriptase. Matthew W Kellinger, Kenneth A Johnson Proceedings of the National Academy of Sciences of the United States of America 2010 partial results
N1-Alkyl pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Michael L Mitchell, Jong Chan Son, Hongyan Guo, Yun-A Im, Eun Jung Cho, Jianhong Wang, Jaclyn Hayes, Michael Wang, Amber Paul, Eric B Lansdon, James M Chen, Doris Graupe, Gerry Rhodes, Gong-Xin He, Romas Geleziunas, Lianhong Xu, Choung U Kim Bioorganic & medicinal chemistry letters 2010 partial results
Exploration of piperidine-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-Phenyl derivatives with broad potency against resistant mutant viruses. Guozhi Tang, Denis J Kertesz, Minmin Yang, Xianfeng Lin, Zhengqiang Wang, Wentao Li, Zongxing Qiu, Junli Chen, Jianghua Mei, Li Chen, Taraneh Mirzadegan, Seth F Harris, Armando G Villaseñor, Jennifer Fretland, William L Fitch, Julie Qi Hang, Gabrielle M Heilek, Klaus Klumpp Bioorganic & medicinal chemistry letters 2010 complete Guozhi Tang*
Stable interaction between the human proliferating cell nuclear antigen loader complex Ctf18-replication factor C (RFC) and DNA polymerase {epsilon} is mediated by the cohesion-specific subunits, Ctf18, Dcc1, and Ctf8. Takeshi Murakami, Ryuji Takano, Satoshi Takeo, Rina Taniguchi, Kaori Ogawa, Eiji Ohashi, Toshiki Tsurimoto The Journal of biological chemistry 2010 new
Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors. Hua-Poo Su, Youwei Yan, G Sridhar Prasad, Robert F Smith, Christopher L Daniels, Pravien D Abeywickrema, John C Reid, H Marie Loughran, Maria Kornienko, Sujata Sharma, Jay A Grobler, Bei Xu, Vinod Sardana, Timothy J Allison, Peter D Williams, Paul L Darke, Daria J Hazuda, Sanjeev Munshi J Virol 2010 partial results
The mechanism of the translocation step in DNA replication by DNA polymerase I: a computer simulation analysis. Andrei A Golosov, Joshua J Warren, Lorena S Beese, Martin Karplus Structure (London, England : 1993) 2010 topics set
Potentiation of temozolomide cytotoxicity by inhibition of DNA polymerase beta is accentuated by BRCA2 mutation. Gregory C Stachelek, Shibani Dalal, Katherine A Donigan, Denise Campisi Hegan, Joann B Sweasy, Peter M Glazer Cancer research 2010 new
Structure and mechanism of human DNA polymerase eta. Christian Biertümpfel, Yaofeng Zhao, Yuji Kondo, Santiago Ramón-Maiques, Mark T Gregory, Jae Young Lee, Chikahide Masutani, Alan R Lehmann, Fumio Hanaoka, Wei Wen Yang Nature 2010 complete Fumio Hanaoka*
EARLY IN SHORT DAYS 7 (ESD7) encodes the catalytic subunit of DNA polymerase epsilon and is required for flowering repression through a mechanism involving epigenetic gene silencing. Iván del Olmo, Leticia López-González, Maria M Martín-Trillo, José M Martínez-Zapater, Manuel Piñeiro, Jose A Jarillo Plant J 2010 complete Jose A Jarillo*
Processive replication of single DNA molecules in a nanopore catalyzed by phi29 DNA polymerase. Kate R Lieberman, Gerald M Cherf, Michael J Doody, Felix Olasagasti, Yvette Kolodji, Mark Akeson Journal of the American Chemical Society 2010 complete Kate R Lieberman*
Reversal of a mutator activity by a nearby fidelity-neutral substitution in the RB69 DNA polymerase binding pocket. Anna Trzemecka, Agata Jacewicz, Geraldine T Carver, John W Drake, Anna Bebenek Journal of molecular biology 2010 pols set
Pushing the limits for amplifying BrdU-labeled DNA encoding 16S rRNA: DNA polymerase as the determining factor. Dad D Roux-Michollet, Joshua P Schimel, Patricia A Holden J Microbiol Methods 2010 complete Dad D Roux-Michollet*
Kinetics of mismatch formation opposite lesions by the replicative DNA polymerase from bacteriophage RB69. Matthew Hogg, Jean Rudnicki, John Midkiff, Linda J Reha-Krantz, Sylvie Doublié, Susan S Wallace Biochemistry 2010 topics set
Study on suitability of KOD DNA polymerase for enzymatic production of artificial nucleic acids using base/sugar modified nucleoside triphosphates. Masayasu Kuwahara, Yuuki Takano, Yuuya Kasahara, Hiroki Nara, Hiroaki Ozaki, Hiroaki Sawai, Akio Sugiyama, Satoshi Obika Molecules 2010 new
[Inhibition of growth and proliferation of Hep-2 cells by targeting hTERT gene using small interference RNA technology]. Haiying Jia, Tao Zhang, Zhi Tang, Jiqun Wang Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 2010 new
Hepatitis C virus core protein induces malignant transformation of biliary epithelial cells by activating nuclear factor-kappaB pathway. Zhi-Hua Li, Qi-Bin Tang, Jie Wang, Ling Zhou, Wen-Lin Huang, Ran-Yi Liu, Ru-Fu Chen Journal of gastroenterology and hepatology 2010 new
DNA polymerase structure-based insight on the mutagenic properties of 8-oxoguanine. William A Beard, Vinod K Batra, Samuel H Wilson Mutation research 2010 topics set
Modifications to the dNTP triphosphate moiety: from mechanistic probes for DNA polymerases to antiviral and anti-cancer drug design. Charles E McKenna, Boris A Kashemirov, Larryn W Peterson, Myron F Goodman Biochimica et biophysica acta 2010 new
The eukaryotic replicative DNA polymerases take shape. Erik Johansson, Stuart A Macneill Trends in biochemical sciences 2010 pols set
Base excision repair and design of small molecule inhibitors of human DNA polymerase beta. Samuel H Wilson, William A Beard, David D Shock, Vinod K Batra, Nisha A Cavanaugh, Rajendra Prasad, Esther W Hou, Yuan Liu, Kenjiro Asagoshi, Julie K Horton, Donna F Stefanick, Padmini S Kedar, Michael J Carrozza, Aya Masaoka, Michelle L Heacock Cell Mol Life Sci 2010 pols set
Structural basis of ubiquitin recognition by translesion synthesis DNA polymerase iota. Gaofeng Cui, Robert C Benirschke, Han-Fang Tuan, Nenad Juranić, Slobodan Macura, Maria Victoria Botuyan, Georges Mer Biochemistry 2010 new
The N348I mutation at the connection subdomain of HIV-1 reverse transcriptase decreases binding to nevirapine. Matthew M Schuckmann, Bruno Marchand, Atsuko Hachiya, Eiichi N Kodama, Karen A Kirby, Kamalendra Singh, Stefan G Sarafianos The Journal of biological chemistry 2010 pols set
The mitochondrial DNA polymerase in health and disease. William C Copeland Subcell Biochem 2010 new
Reconstitution of the B. subtilis replisome with 13 proteins including two distinct replicases. Glenn M Sanders, H Garry Dallmann, Charles S McHenry Molecular cell 2010 new
[Ratio of 3' --> 5'-exonuclease and DNA-polymerase activities in normal and cancer cells of rodents and humans]. T P Kravetskaia, N L Ronzhina, V M Krutiakov Tsitologiia 2010 new
Participation of DNA polymerase zeta in replication of undamaged DNA in Saccharomyces cerevisiae. Matthew R Northam, Heather A Robinson, Olga V Kochenova, Polina V Shcherbakova Genetics 2010 new
Factors affecting template usage in the development of K65R resistance in subtype C variants of HIV type-1. Dimitrios Coutsinos, Cédric F Invernizzi, Hongtao Xu, Bluma G Brenner, Mark A. Wainberg Antiviral chemistry & chemotherapy 2010 pols set
Intrinsic apurinic/apyrimidinic (AP) endonuclease activity enables Bacillus subtilis DNA polymerase X to recognize, incise, and further repair abasic sites. Benito Baños, Laurentino Villar, Margarita Salas, Miguel de Vega Proceedings of the National Academy of Sciences of the United States of America 2010 pols set
A nuclear family A DNA polymerase from Entamoeba histolytica bypasses thymine glycol. Guillermo Pastor-Palacios, Elisa Azuara-Liceaga, Luis G Brieba PLoS Negl Trop Dis 2010 new
Optimization of DNA polymerase mutation rates during bacterial evolution. Ern Loh, Jesse J Salk, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 2010 new
DNA polymerase family X: function, structure, and cellular roles. Jennifer Yamtich, Joann B Sweasy Biochimica et biophysica acta 2010 partial results
Comparative biochemical analysis of recombinant reverse transcriptase enzymes of HIV-1 subtype B and subtype C. Hong-Tao Xu, Yudong Quan, Eugene L Asahchop, Maureen Oliveira, Daniella Moisi, Mark A. Wainberg Retrovirology 2010 pols set
Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. Matthew J Cuneo, Robert E London Proceedings of the National Academy of Sciences of the United States of America 2010 topics set
DNA polymerase eta protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy. Kai-yuan Teng, Miao-zhen Qiu, Zhuang-hua Li, Hui-yan Luo, Zhao-lei Zeng, Rong-zhen Luo, Hui-zhong Zhang, Zhi-qiang Wang, Yu-hong Li, Rui-hua Xu J Transl Med 2010 new
Higher levels of Zidovudine resistant HIV in the colon compared to blood and other gastrointestinal compartments in HIV infection. Guido van Marle, Deirdre L Church, Kali D Nunweiler, Kris Cannon, Mark A. Wainberg, M John Gill Retrovirology 2010 pols set
Genome instability due to ribonucleotide incorporation into DNA. Stephanie A Nick McElhinny, Dinesh Kumar, Alan B Clark, Danielle L Watt, Brian E Watts, Else-Britt Lundström, Erik Johansson, Andrei Chabes, Thomas A Kunkel Nature chemical biology 2010 new
Metal-ion dependence of the active-site conformation of the translesion DNA polymerase Dpo4 from Sulfolobus solfataricus. Adriana Irimia, Lioudmila V Loukachevitch, Robert Lawton Eoff, F Peter Guengerich, Martin Egli Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 pols set
Error-free replicative bypass of (6-4) photoproducts by DNA polymerase zeta in mouse and human cells. Jung-Hoon Yoon, Louise Prakash, Satya Prakash Genes Dev 2010 new
Genome-wide model for the normal eukaryotic DNA replication fork. Andres A Larrea, Scott A Lujan, Stephanie A Nick McElhinny, Piotr A Mieczkowski, Michael A Resnick, Dmitry A Gordenin, Thomas A Kunkel Proceedings of the National Academy of Sciences of the United States of America 2010 new
Real-time monitoring of DNA polymerase function and stepwise single-nucleotide DNA strand translocation through a protein nanopore. John Chu, Marcos González-López, Scott L Cockroft, Manuel Amorin, M Reza Ghadiri Angew Chem Int Ed Engl 2010 topics set
[Effects of DNA polymerase beta on certain genotoxicity of mouse fibroblast cell induced by hydroquinone]. Chen Chen, Yanhao Lai, Mei Wu, Zhenzhong Zhang Wei sheng yan jiu = Journal of hygiene research 2010 pols set
Direct polymerase synthesis of reactive aldehyde-functionalized DNA and its conjugation and staining with hydrazines. Veronika Raindlová, Radek Pohl, Miloslav Sanda, Michal Hocek Angewandte Chemie (International ed. in English) 2010 topics set
A cluster of pathogenic mutations in the 3'-5' exonuclease domain of DNA polymerase gamma defines a novel module coupling DNA synthesis and degradation. Karolina Szczepanowska, Françoise Foury Hum Mol Genet 2010 new
Replication of individual DNA molecules under electronic control using a protein nanopore. Felix Olasagasti, Kate R Lieberman, Seico Benner, Gerald M Cherf, Joseph M Dahl, David W Deamer, Mark Akeson Nature nanotechnology 2010 topics set
A mutant Pfu DNA polymerase designed for advanced uracil-excision DNA engineering. Morten H H Nørholm BMC Biotechnol 2010 pols set
A binding free energy decomposition approach for accurate calculations of the fidelity of DNA polymerases. Robert Rucker, Peter Oelschlaeger, Arieh Warshel Proteins 2010 topics set
Residues in the central beta-hairpin of the DNA helicase of bacteriophage T7 are important in DNA unwinding. Ajit K Satapathy, Anna B Kochaniak, Sourav Mukherjee, DJ Crampton, Antoine M van Oijen, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 2010 pols set
Direct role for the RNA polymerase domain of T7 primase in primer delivery. B Zhu, Seung-Joo Lee, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 2010 new
Structural basis of HIV-1 resistance to AZT by excision. Xiongying Tu, Kalyan Das, Qianwei Han, Joseph David Bauman, Arthur D Clark, Xiaorong Hou, Yulia Volovik Frenkel, Barbara L Gaffney, Roger A Jones, Paul L Boyer, Stephen H Hughes, Stefan G Sarafianos, Edward Arnold Nature structural & molecular biology 2010 pols set
Comparison of the in vitro replication of the 7-(2-oxoheptyl)-1,N2-etheno-2'-deoxyguanosine and 1,N2-etheno-2'-deoxyguanosine lesions by Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4). Plamen P Christov, Katya V Petrova, Ganesh Shanmugam, Ivan D Kozekov, Albena Kozekova, F Peter Guengerich, Michael P Stone, Carmelo J Rizzo Chemical research in toxicology 2010 new
The mutation T477A in HIV-1 reverse transcriptase (RT) restores normal proteolytic processing of RT in virus with Gag-Pol mutated in the p51-RNH cleavage site. Michael E Abram, Stefan G Sarafianos, Michael A. Parniak Retrovirology 2010 pols set
Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4. Olga Rechkoblit, Alexander Kolbanovskiy, Lucy Malinina, Nicholas E Geacintov, Suse Broyde, Dinshaw J Patel Nature structural & molecular biology 2010 topics set
Viral terminal protein directs early organization of phage DNA replication at the bacterial nucleoid. Daniel Muñoz-Espín, Isabel Holguera, David Ballesteros-Plaza, Rut Carballido-López, Margarita Salas Proceedings of the National Academy of Sciences of the United States of America 2010 new
The carboxy-terminal segment of the human cytomegalovirus DNA polymerase accessory subunit UL44 is crucial for viral replication. Laurie A Silva, Arianna Loregian, Gregory S Pari, Blair L Strang, Donald M Coen Journal of virology 2010 pols set
A new model for SOS-induced mutagenesis: how RecA protein activates DNA polymerase V. Meghna Patel, Qingfei Jiang, Roger Woodgate, Michael M Cox, Myron F Goodman Crit Rev Biochem Mol Biol 2010 new
Effect of acyclovir on HIV-1 set point among herpes simplex virus type 2-seropositive persons during early HIV-1 infection. H Nina Kim, Jing Wang, James Hughes, Robert Coombs, Jorge Sanchez, Stewart Reid, Sinead Delany-Moretlwe, Frances Cowan, Jonathan Fuchs, Susan H Eshleman, Leila Khaki, Moira A McMahon, Robert F Siliciano, Anna Wald, Connie Celum The Journal of infectious diseases 2010 pols set
Hybrid diarylbenzopyrimidine non-nucleoside reverse transcriptase inhibitors as promising new leads for improved anti-HIV-1 chemotherapy. Zhao-Sen Zeng, Qiu-Qin He, Yong-Hong Liang, Xiao-Qing Feng, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Bioorganic & medicinal chemistry 2010 pols set
Telomere healing following DNA polymerase arrest-induced breakages is likely the main mechanism generating chromosome 4p terminal deletions. Femke Hannes, Jeroen Van Houdt, Oliver W Quarrell, Martin Poot, Ron Hochstenbach, Jean-Pierre Fryns, Joris R Vermeesch Hum Mutat 2010 topics set
Differential correction of lagging-strand replication errors made by DNA polymerases {alpha} and {delta}. Stephanie A Nick McElhinny, Grace E Kissling, Thomas A Kunkel Proceedings of the National Academy of Sciences of the United States of America 2010 new
Targeted radiosensitization of cells expressing truncated DNA polymerase {beta}. Sari Neijenhuis, Manon Verwijs-Janssen, Lenie J van den Broek, Adrian C Begg, Conchita Vens Cancer research 2010 new
Analysis of DNA methylation status of the promoter of human telomerase reverse transcriptase in gastric carcinogenesis. Zhengqiang Wang, Jinheng Xu, Xin Geng, Weiming Zhang Archives of medical research 2010 new
Pharmacophore and structure-activity relationships of integrase inhibition within a dual inhibitor scaffold of HIV reverse transcriptase and integrase. Zhengqiang Wang, Jing Tang, Christine E Salomon, Christine D Dreis, Robert Vince Bioorganic & medicinal chemistry 2010 pols set
Yeast telomerase subunit Est1p has guanine quadruplex-promoting activity that is required for telomere elongation. Ming-Liang Zhang, Xia-Jing Tong, Xiao-Hong Fu, Bo O Zhou, Jianyong Wang, Xin-Hua Liao, Qian-Jin Li, Ning Shen, Jianping Ding, Jin-Qiu Zhou Nature structural & molecular biology 2010 new
Lead optimization of diarylpyrimidines as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Zhao-Sen Zeng, Yong-Hong Liang, Xiao-Qing Feng, Fen-Er Chen, Christophe Pannecouque, Jan Balzarini, Erik De Clercq ChemMedChem 2010 pols set
The glycine-rich motif of Pyrococcus abyssi DNA polymerase D is critical for protein stability. Benoît Castrec, Sébastien Laurent, Ghislaine Henneke, Didier Flament, Jean-Paul Raffin Journal of molecular biology 2010 pols set
Inhibition of short patch and long patch base excision repair by an oxidized abasic site. Lirui Guan, Katarzyna Bebenek, Thomas A Kunkel, Marc M Greenberg Biochemistry 2010 topics set
Leptin upregulates telomerase activity and transcription of human telomerase reverse transcriptase in MCF-7 breast cancer cells. He Ren, Tiansuo Zhao, Xiuchao Wang, Chuntao Gao, Jian Wang, Ming Yu, Jihui Hao Biochemical and biophysical research communications 2010 new
Synthesis and anti-HIV activity of 2-naphthyl substituted DAPY analogues as non-nucleoside reverse transcriptase inhibitors. Yong-Hong Liang, Qiu-Qin He, Zhao-Sen Zeng, Zhi-Qian Liu, Xiao-Qing Feng, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq Bioorganic & medicinal chemistry 2010 pols set
Sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO) in a sibling pair with a homozygous p.A467T POLG mutation. John C McHugh, Roisin Lonergan, Rachel Howley, Killian O'Rourke, Robert W Taylor, Michael Farrell, Michael Hutchinson, Sean Connolly Muscle & nerve 2010 pols set
Selective modulation of DNA polymerase activity by fixed-conformation nucleoside analogues. Robert Lawton Eoff, Colleen E McGrath, Leena Maddukuri, S Giovanna Salamanca-Pinzón, Victor E Marquez, Lawrence J Marnett, F Peter Guengerich, Martin Egli Angewandte Chemie (International ed. in English) 2010 new
Substrate channeling in mammalian base excision repair pathways: passing the baton. Rajendra Prasad, David D Shock, William A Beard, Samuel H Wilson The Journal of biological chemistry 2010 new
Simultaneous disruption of two DNA polymerases, Polη and Polζ, in Avian DT40 cells unmasks the role of Polη in cellular response to various DNA lesions. Kouji Hirota, Eiichiro Sonoda, Takuo Kawamoto, Akira Motegi, Chikahide Masutani, Fumio Hanaoka, Dávid Szüts, Shigenori Iwai, Julian E Sale, Alan R Lehmann, Shunichi Takeda PLoS genetics 2010 complete Shunichi Takeda*
Nucleolin associates with the human cytomegalovirus DNA polymerase accessory subunit UL44 and is necessary for efficient viral replication. Blair L Strang, Steeve Boulant, Donald M Coen Journal of virology 2010 pols set
Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine . Jeff W Beckman, Michael Wang, Gregor Blaha, Jianhong Wang, William H Konigsberg Biochemistry 2010 topics set
Active site mutations in mammalian DNA polymerase delta alter accuracy and replication fork progression. Michael W Schmitt, Ranga N Venkatesan, Marie-Jeanne Pillaire, Jean-Sébastien Hoffmann, Julia M Sidorova, Lawrence A Loeb The Journal of biological chemistry 2010 pols set
Crystal structures of HIV-1 reverse transcriptase with etravirine (TMC125) and rilpivirine (TMC278): implications for drug design. Eric B Lansdon, Katherine M Brendza, Magdeleine Hung, Ruth Wang, Susmith Mukund, Debi Jin, Gabriel Birkus, Nilima Kutty, Xiaohong Liu J Med Chem 2010 complete Eric B Lansdon*
Cerebral folate deficiency and CNS inflammatory markers in Alpers disease. Oswald Hasselmann, Nenad Blau, Vincent T Ramaekers, Edward V Quadros, J M Sequeira, Markus Weissert Molecular genetics and metabolism 2010 complete Oswald Hasselmann*
Effect of human cell malignancy on activity of DNA polymerase iota. Andrey A Kazakov, E E Grishina, Vyacheslav Z Tarantul, Leonid V Gening Biochemistry (Mosc) 2010 new
Pre-steady state kinetic studies of the fidelity of nucleotide incorporation by yeast DNA polymerase delta. Lynne M Dieckman, Robert E Johnson, Satya Prakash, M Todd Washington Biochemistry 2010 new
Virologic outcomes of first-line HAART and associated factors among Chinese patients with HIV in three sentinel antiretroviral treatment sites. Yuhua Ruan, Hui Xing, Xia Wang, Heng Tang, Zhengqiang Wang, Hongwei Liu, Bin Su, Jianjun Wu, Hanping Li, Lingjie Liao, Jinming Li, Julia Wei Wu, Yiming Shao Tropical medicine & international health : TM & IH 2010 pols set
Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin . Jeff W Beckman, Michael Wang, Gregor Blaha, Jianhong Wang, William H Konigsberg Biochemistry 2010 topics set
DNA polymerase fidelity: comparing direct competition of right and wrong dNTP substrates with steady state and pre-steady state kinetics. Jeffrey G Bertram, Keriann Oertell, John Petruska, Myron F Goodman Biochemistry 2010 new
Two modes of interaction of the single-stranded DNA-binding protein of bacteriophage T7 with the DNA polymerase-thioredoxin complex. Sharmistha Ghosh, Samir M Hamdan, Charles C Richardson The Journal of biological chemistry 2010 new
[Effect of DNA polymerase beta on repair of DNA damage induced by benzo(a) pyrene]. Mei Wu, Yanhao Lai, Zhenzhong Zhang Wei sheng yan jiu = Journal of hygiene research 2010 new
Small molecule inhibitors of HIV RT Ribonuclease H. Martin Di Grandi, Matthew Olson, Amar S Prashad, Geraldine Bebernitz, Amara Luckay, Stanley Mullen, Yongbo Hu, Girija Krishnamurthy, Keith Pitts, John O'Connell Bioorganic & medicinal chemistry letters 2010 topics set
N1-Heterocyclic pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Michael L Mitchell, Jong Chan Son, Ill Young Lee, Chong-Kyo Lee, Hae Soo Kim, Hongyan Guo, Jianhong Wang, Jaclyn Hayes, Michael Wang, Amber Paul, Eric B Lansdon, James M Chen, Gene Eisenberg, Romas Geleziunas, Lianhong Xu, Choung U Kim Bioorganic & medicinal chemistry letters 2010 partial results
Discovery of piperidin-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-benzyl derivatives with broad potency against resistant mutant viruses. Denis J Kertesz, Christine Brotherton-Pleiss, Minmin Yang, Zhengqiang Wang, Xianfeng Lin, Zongxing Qiu, Donald R Hirschfeld, Shelley K Gleason, Taraneh Mirzadegan, Pete W Dunten, Seth F Harris, Armando G Villaseñor, Julie Qi Hang, Gabrielle M Heilek, Klaus Klumpp Bioorganic & medicinal chemistry letters 2010 partial results
Slow binding-tight binding interaction between benzimidazol-2-one inhibitors and HIV-1 reverse transcriptase containing the lysine 103 to asparagine mutation. Alberta Samuele, Emmanuele Crespan, Samanta Vitellaro, Anna-Maria Monforte, Patrizia Logoteta, Alba Chimirri, Giovanni Maga Antiviral research 2010 pols set
Conformational dynamics of bacteriophage T7 DNA polymerase and its processivity factor, Escherichia coli thioredoxin. Barak Akabayov, Sabine R Akabayov, Seung-Joo Lee, Stanley Tabor, Arkadiusz W Kulczyk, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 2010 pols set
mip1 containing mutations associated with mitochondrial disease causes mutagenesis and depletion of mtDNA in Saccharomyces cerevisiae. Jeffrey D Stumpf, Christopher M Bailey, Diana Spell, Matthew Stillwagon, Karen S Anderson, William C Copeland Human molecular genetics 2010 topics set
A novel mechanism of sugar selection utilized by a human X-family DNA polymerase. Jessica A Brown, Kevin A Fiala, Jason D Fowler, Shanen M Sherrer, Sean A Newmister, Wade W Duym, Zucai Suo Journal of molecular biology 2010 new
Antiretroviral drugs. Erik De Clercq Current opinion in pharmacology 2010 pols set
Roles of POLD4, smallest subunit of DNA polymerase delta, in nuclear structures and genomic stability of human cells. Qin Miao Huang, Tomohiro Akashi, Yuji Masuda, Kenji Kamiya, Tomonori Takahashi, Motoshi Suzuki Biochem Biophys Res Commun 2010 pols set
Inhibitory effects of diacylglyceride phospholipids on DNA polymerase and topoisomerase activities, and human cancer cell growth. Chisato Ishimaru, Toshifumi Takeuchi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Medicinal chemistry (Shāriqah (United Arab Emirates)) 2010 new
Mechanism of entecavir resistance of hepatitis B virus with viral breakthrough as determined by long-term clinical assessment and molecular docking simulation. Motokazu Mukaide, Yasuhito Tanaka, Tadasu Shin-I, Man-Fung Yuen, Fuat Kurbanov, Osamu Yokosuka, Michio Sata, Yoshiyasu Karino, Gotaro Yamada, Kohsaku Sakaguchi, Etsuro Orito, Manami Inoue, Sumbella Baqai, Ching-Lung Lai, Masashi Mizokami Antimicrobial agents and chemotherapy 2010 new
A single mutation in human mitochondrial DNA polymerase Pol gammaA affects both polymerization and proofreading activities of only the holoenzyme. Young-Sam Lee, Kenneth A Johnson, Ian J Molineux, Y Whitney Yin The Journal of biological chemistry 2010 new
The R438W polymorphism of human DNA polymerase lambda triggers cellular sensitivity to camptothecin by compromising the homologous recombination repair pathway. Jean-Pascal Capp, François Boudsocq, Valérie Bergoglio, Didier Trouche, Christophe Cazaux, Luis Blanco, Jean-Sébastien Hoffmann, Yvan Canitrot Carcinogenesis 2010 pols set
Sensitive and rapid detection of Vibrio corallilyticus by loop-mediated isothermal amplification targeted to the alpha subunit gene of RNA polymerase. G F Liu, Ji-Yang Wang, L W Xu, X Ding, S N Zhou Letters in applied microbiology 2010 new
Rapid detection of peste des petits ruminants virus by a reverse transcription loop-mediated isothermal amplification assay. Lin Li, Jingyue Bao, Xiaoming Wu, Zhengqiang Wang, Junwei Wang, Mingxia Gong, Chunju Liu, Jinming Li Journal of virological methods 2010 pols set
Techniques used to study the DNA polymerase reaction pathway. Catherine M Joyce Biochimica et biophysica acta 2010 new
Unconventional ubiquitin recognition by the ubiquitin-binding motif within the Y family DNA polymerases iota and Rev1. Martha G Bomar, Sanjay D'Souza, Marzena Bienko, Ivan Dikic, Graham C Walker, Pei Zhou Molecular cell 2010 topics set
Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin. Pierre Aller, Yu Ye, Susan S Wallace, Cynthia J Burrows, Sylvie Doublié Biochemistry 2010 topics set
Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1. Kodai Hara, Hiroshi Hashimoto, Yoshiki Murakumo, Shunsuke Kobayashi, Toshiaki Kogame, Satoru Unzai, Satoko Akashi, Shunichi Takeda, Toshiyuki Shimizu, Mamoru Sato The Journal of biological chemistry 2010 new
A sulfoglycolipid beta-sulfoquinovosyldiacylglycerol (betaSQDG) binds to Met1-Arg95 region of murine DNA polymerase lambda (Mmpol lambda) and inhibits its nuclear transit. K Takakusagi, Yoichi Takakusagi, Keisuke Ohta, Satoko Aoki, Fumio Sugawara, Kengo Sakaguchi Protein Eng Des Sel 2010 new
DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability. Fanny Lemée, Valérie Bergoglio, Anne Fernandez-Vidal, Alice Machado-Silva, Marie-Jeanne Pillaire, Anne Bieth, Catherine Gentil, Lee Baker, Anne-Laure Martin, Claire Leduc, Elena Lam, Eddy Magdeleine, Thomas Filleron, Naïma Oumouhou, Bernd Kaina, Masayuki Seki, Fanny Grimal, Magali Lacroix-Triki, Alastair Thompson, Henri Roché, Jean-Christophe Bourdon, Richard D Wood, Jean-Sébastien Hoffmann, Christophe Cazaux Proceedings of the National Academy of Sciences of the United States of America 2010 new
Structure-activity analysis of vinylogous urea inhibitors of human immunodeficiency virus-encoded ribonuclease H. Suhman Chung, Michaela Wendeler, Jason W Rausch, Greg L Beilhartz, Matthias Gotte, Barry R O'Keefe, Alun Bermingham, John A Beutler, Shixin Liu, Xiaowei Zhuang, Stuart F J Le Grice Antimicrobial agents and chemotherapy 2010 pols set
Poly(ADP-ribose) polymerase 1 regulates activity of DNA polymerase beta in long patch base excision repair. Maria V Sukhanova, Svetlana N Khodyreva, Olga I Lavrik Mutation research 2010 new
Mutagenic conformation of 8-oxo-7,8-dihydro-2'-dGTP in the confines of a DNA polymerase active site. Vinod K Batra, William A Beard, Esther W Hou, Lars C Pedersen, Rajendra Prasad, Samuel H Wilson Nature structural & molecular biology 2010 new
Biochemical techniques for the characterization of G-quadruplex structures: EMSA, DMS footprinting, and DNA polymerase stop assay. Daekyu Sun, Laurence H Hurley Methods in molecular biology (Clifton, N.J.) 2010 new
Association between the herpes simplex virus-1 DNA polymerase and uracil DNA glycosylase. Federica Bogani, Ilsa Corredeira, Virneliz Fernandez, Ulrike Sattler, Wiriya Rutvisuttinunt, Martine Defais, Paul E Boehmer The Journal of biological chemistry 2010 new
Structure of a DNA polymerase alpha-primase domain that docks on the SV40 helicase and activates the viral primosome. Hao Huang, Brian E Weiner, Haijiang Zhang, Brian E Fuller, Yue Gao, Brian M Wile, Kun Zhao, Diana R Arnett, Walter J Chazin, Ellen Fanning The Journal of biological chemistry 2010 new
Irreversible inhibition of DNA polymerase beta by an oxidized abasic lesion. Lirui Guan, Marc M Greenberg Journal of the American Chemical Society 2010 new
Inhibitory effect of somatostatin Peptide analogues on DNA polymerase activity and human cancer cell proliferation. Isoko Kuriyama, Anna Miyazaki, Yuko Tsuda, Toshio Yokoi, Yoshio Okada, Toshifumi Takeuchi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Anticancer Res 2010 new
A highly active DNA polymerase with a fluorous core. Bastian Holzberger, Marina Rubini, Heiko M Möller, Andreas Marx Angew Chem Int Ed Engl 2010 new
Loop 1 modulates the fidelity of DNA polymerase {lambda} Katarzyna Bebenek, Miguel Garcia-Diaz, Rui-Zhe Zhou, Lawrence F Povirk, Thomas A Kunkel Nucleic acids research 2010 partial results
Polymerization by DNA polymerase eta is blocked by cis-diamminedichloroplatinum(II) 1,3-d(GpTpG) cross-link: implications for cytotoxic effects in nucleotide excision repair-negative tumor cells. Shotaro Chijiwa, Chikahide Masutani, Fumio Hanaoka, Shigenori Iwai, Isao Kuraoka Carcinogenesis 2010 new
Rare autosomal dominant POLG1 mutation in a family with metabolic strokes, posterior column spinal degeneration, and multi-endocrine disease. Sarah E Hopkins, Arthur Somoza, Donald L Gilbert Journal of child neurology 2010 pols set
Polymerization behavior of Klenow fragment and Taq DNA polymerase in short primer extension reactions. Guojie Zhao, Yifu Guan Acta Biochim Biophys Sin (Shanghai) 2010 topics set
Effect of N2-guanyl modifications on early steps in catalysis of polymerization by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W. Haijiang Zhang, F Peter Guengerich Journal of molecular biology 2010 new
Computational model of hepatitis B virus DNA polymerase: molecular dynamics and docking to understand resistant mutations. Pankaj R Daga, Jinsong Duan, Robert J Doerksen Protein science : a publication of the Protein Society 2010 complete Robert J Doerksen*
Differential impact of the HIV-1 non-nucleoside reverse transcriptase inhibitor mutations K103N and M230L on viral replication and enzyme function. Hong-Tao Xu, Maureen Oliveira, Yudong Quan, Tamara Bar-Magen, Mark A. Wainberg The Journal of antimicrobial chemotherapy 2010 pols set
Early nucleoside reverse transcriptase inhibitors for the treatment of HIV: a brief history of stavudine (D4T) and its comparison with other dideoxynucleosides. John C Martin, Michael J M Hitchcock, Erik De Clercq, William H Prusoff Antiviral research 2010 pols set
Ubc4 and Not4 regulate steady-state levels of DNA polymerase-alpha to promote efficient and accurate DNA replication. Justin Haworth, Robert C Alver, Melissa Anderson, Anja-Katrin Bielinsky Mol Biol Cell 2010 new
Crystal Structure of a Cisplatin-(1,3-GTG) Cross-Link within DNA Polymerase eta. Thomas Reissner, Sabine Schneider, Stephanie Schorr, Thomas Carell Angew Chem Int Ed Engl 2010 topics set
Significance of DNA polymerase delta catalytic subunit p125 induced by mutant p53 in the invasive potential of human hepatocellular carcinoma. Kensaku Sanefuji, Akinobu Taketomi, Tomohiro Iguchi, Keishi Sugimachi, Toru Ikegami, Yo-ichi Yamashita, Tomonobu Gion, Yuji Soejima, Ken Shirabe, Yoshihiko Maehara Oncology 2010 pols set
Loss of DNA polymerase zeta enhances spontaneous tumorigenesis. John P Wittschieben, Vaishali Patil, Veronika Glushets, Lisa J Robinson, Donna F Kusewitt, Richard D Wood Cancer research 2010 new
A single subunit directs the assembly of the Escherichia coli DNA sliding clamp loader. Ah Young Park, Slobodan Jergic, Argyris Politis, Brandon T Ruotolo, Daniel Hirshberg, Linda L Jessop, Jennifer L Beck, Daniel Barsky, Mike E O'Donnell, Nicholas E Dixon, Carol V Robinson Structure (London, England : 1993) 2010 topics set
Conformational transitions in DNA polymerase I revealed by single-molecule FRET. Yusdi Santoso, Catherine M Joyce, Olga Potapova, Ludovic Le Reste, Johannes Hohlbein, Joseph P Torella, Nigel D F Grindley, Achillefs N Kapanidis Proceedings of the National Academy of Sciences of the United States of America 2010 new
Structural basis for proficient incorporation of dTTP opposite O6-methylguanine by human DNA polymerase iota. Matthew G Pence, Jeong-Yun Choi, Martin Egli, F Peter Guengerich The Journal of biological chemistry 2010 pols set
Inhibitory effects of sulfobacin B on DNA polymerase and inflammation. Jun Maeda, Masayuki Nishida, Hirosato Takikawa, Hiromi Yoshida, Takeshi Azuma, Masaru Yoshida, Yoshiyuki Mizushina Int J Mol Med 2010 new
An amino acid residue in the middle of the fingers subdomain is involved in Neq DNA polymerase processivity: enhanced processivity of engineered Neq DNA polymerase and its PCR application. Jae-Geun Song, Eui-Joon Kil, Sung Suk Cho, In Hye Kim, Suk-Tae Kwon Protein Eng Des Sel 2010 new
A DNA polymerase with increased reactivity for ribonucleotides and C5-modified deoxyribonucleotides. Nadine Staiger, Andreas Marx Chembiochem 2010 new
Crystal Structure of HIV-1 Reverse Transcriptase Bound to a Non-Nucleoside Inhibitor with a Novel Mechanism of Action. Séverine Freisz, Guillaume Bec, Marco Radi, Philippe Wolff, Emmanuele Crespan, Lucilla Angeli, Philippe Dumas, Giovanni Maga, Maurizio Botta, Eric Ennifar Angew Chem Int Ed Engl 2010 partial results
Pre-Steady-State Kinetic Analysis of Truncated and Full-Length Saccharomyces cerevisiae DNA Polymerase Eta. Jessica A Brown, Likui Zhang, Shanen M Sherrer, John-Stephen Taylor, Peter M J Burgers, Zucai Suo J Nucleic Acids 2010 partial results
Compartmentalized self-replication (CSR) selection of Thermococcus litoralis Sh1B DNA polymerase for diminished uracil binding. Agne Tubeleviciute, Remigijus Skirgaila Protein engineering, design 2010 topics set
A novel POLG gene mutation in 4 children with Alpers-like hepatocerebral syndromes. Bulent Kurt, Jaak Jaeken, Johan Van Hove, Lieven Lagae, Ann Löfgren, David B Everman, Parul Jayakar, Ali B Naini, Klaas J Wierenga, Gert Van Goethem, William C Copeland, Salvatore DiMauro Archives of neurology 2010 pols set
Consecutive incorporation of fluorophore-labeled nucleotides by mammalian DNA polymerase beta. Ken Hirano, Yuichiro Yoshida, Tomomi Ishido, Yukihisa Wada, Naoji Moriya, Naoshi Yamazaki, Yoshiyuki Mizushina, Yoshinobu Baba, Mitsuru Ishikawa Anal Biochem 2010 topics set
Stable interactions between DNA polymerase delta catalytic and structural subunits are essential for efficient DNA repair. Clémentine Brocas, Jean-Baptiste Charbonnier, Claudine Dhérin, Serge Gangloff, Laurent Maloisel DNA repair 2010 new
Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase eta. Timothy D Silverstein, Rinku Jain, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Structure (London, England : 1993) 2010 topics set
Functions of base selection step in human DNA polymerase alpha. Shigeru Tanaka, Ke Cao, Atsuko Niimi, Siripan Limsirichaikul, Huang Qin Miao, Noriko Nakamura, Takashi Murate, Yoshinori Hasegawa, Tomonori Takahashi, Motoshi Suzuki DNA repair 2010 topics set
The kinetic and chemical mechanism of high-fidelity DNA polymerases. Kenneth A Johnson Biochimica et biophysica acta 2010 new
A new thermostable DNA polymerase mixture for efficient amplification of long DNA fragments. K G Davalieva, G D Efremov Prikl Biokhim Mikrobiol 2010 pols set
The interaction between DNA polymerase lambda and anticancer nucleoside analogs. Miguel Garcia-Diaz, Michael S Murray, Thomas A Kunkel, Kai-Ming Chou The Journal of biological chemistry 2010 topics set
Stage-dependent inhibition of HIV-1 replication by antiretroviral drugs in cell culture. Daniel A Donahue, Richard D Sloan, Björn D Kuhl, Tamara Bar-Magen, Susan M Schader, Mark A. Wainberg Antimicrobial agents and chemotherapy 2010 pols set
Refolding active human DNA polymerase nu from inclusion bodies. Mercedes E Arana, Gary K Powell, Lori L Edwards, Thomas A Kunkel, Robert M Petrovich Protein Expr Purif 2010 pols set
Novel enzymatic function of DNA polymerase nu in translesion DNA synthesis past major groove DNA-peptide and DNA-DNA cross-links. Kinrin Yamanaka, Irina G Minko, Kei-ichi Takata, Alexander Kolbanovskiy, Ivan D Kozekov, Richard D Wood, Carmelo J Rizzo, R Stephen Lloyd Chemical research in toxicology 2010 new
Lack of DNA polymerase mu affects the kinetics of DNA double-strand break repair and impacts on cellular senescence. Romain Chayot, Anne Danckaert, Benjamin Montagne, Miria Ricchetti DNA repair 2010 pols set
A mechanistic view of human mitochondrial DNA polymerase gamma: providing insight into drug toxicity and mitochondrial disease. Christopher M Bailey, Karen S Anderson Biochimica et biophysica acta 2010 new
Coordinating DNA polymerase traffic during high and low fidelity synthesis. Mark D Sutton Biochimica et biophysica acta 2010 pols set
DNA polymerase proofreading: Multiple roles maintain genome stability. Linda J Reha-Krantz Biochimica et biophysica acta 2010 complete
Mismatch repair-independent increase in spontaneous mutagenesis in yeast lacking non-essential subunits of DNA polymerase epsilon. Anna Y Aksenova, Kirill Volkov, Jaroslaw Maceluch, Zachary F Pursell, Igor B Rogozin, Thomas A Kunkel, Youri I Pavlov, Erik Johansson PLoS Genet 2010 topics set
Replacing 32 proline residues by a noncanonical amino acid results in a highly active DNA polymerase. Bastian Holzberger, Andreas Marx Journal of the American Chemical Society 2010 topics set
Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid. G K Surya Prakash, Mikhail Zibinsky, Thomas G Upton, Boris A Kashemirov, Charles E McKenna, Keriann Oertell, Myron F Goodman, Vinod K Batra, Lars C Pedersen, William A Beard, David D Shock, Samuel H Wilson, George A Olah Proceedings of the National Academy of Sciences of the United States of America 2010 topics set
Directed evolution of DNA polymerases: construction and screening of DNA polymerase mutant libraries. Christian Gloeckner, Ramon Kranaster, Andreas Marx Current protocols in chemical biology 2010 topics set
Identification of a new motif in family B DNA polymerases by mutational analyses of the bacteriophage t4 DNA polymerase. Vincent Li, Matthew Hogg, Linda J Reha-Krantz Journal of molecular biology 2010 complete
Role of histidine 932 of the human mitochondrial DNA polymerase in nucleotide discrimination and inherited disease. Dipanwita Batabyal, Jessica L McKenzie, Kenneth A Johnson The Journal of biological chemistry 2010 new
One-step RNA pathogen detection with reverse transcriptase activity of a mutated thermostable Thermus aquaticus DNA polymerase. Ramon Kranaster, Matthias Drum, Nicole Engel, Manfred Weidmann, Frank T Hufert, Andreas Marx Biotechnology journal 2010 pols set
Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases. Stephanie A Nick McElhinny, Brian E Watts, Dinesh Kumar, Danielle L Watt, Else-Britt Lundström, Peter M J Burgers, Erik Johansson, Andrei Chabes, Thomas A Kunkel Proceedings of the National Academy of Sciences of the United States of America 2010 partial results
A cancer-associated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in genomic instability. Danielle L Daee, Tony M Mertz, Polina V Shcherbakova Proceedings of the National Academy of Sciences of the United States of America 2010 new
Each monomer of the dimeric accessory protein for human mitochondrial DNA polymerase has a distinct role in conferring processivity. Young-Sam Lee, Sujin Lee, Borries Demeler, Ian J Molineux, Kenneth A Johnson, Y Whitney Yin The Journal of biological chemistry 2010 new
DNA polymerase beta is critical for mouse meiotic synapsis. Dawit Kidane, Alan S Jonason, Timothy S Gorton, Ivailo Mihaylov, Jing Pan, Scott Keeney, Dirk G de Rooij, Terry Ashley, Agnes Keh, Yanfeng Liu, Urmi Banerjee, Daniel Zelterman, Joann B Sweasy The EMBO journal 2010 new
Solution structure of the N-terminal domain of the archaeal D-family DNA polymerase small subunit reveals evolutionary relationship to eukaryotic B-family polymerases. Kazuhiko Yamasaki, Yuji Urushibata, Tomoko Yamasaki, Fumio Arisaka, Ikuo Matsui FEBS letters 2010 topics set
Parallel multiplicative target screening against divergent bacterial replicases: identification of specific inhibitors with broad spectrum potential. H Garry Dallmann, Oliver J Fackelmayer, Guy Tomer, Joe Chen, Anna Wiktor-Becker, Tracey Ferrara, Casey Pope, Marcos T Oliveira, Peter M J Burgers, Laurie S Kaguni, Charles S McHenry Biochemistry 2010 new
A phase I study of telomerase-specific replication competent oncolytic adenovirus (telomelysin) for various solid tumors. John Nemunaitis, Alex W Tong, Michael Nemunaitis, Neil Senzer, Anagha P Phadke, Cynthia Bedell, Ned Adams, Yu-An Zhang, Phillip B Maples, Salina Chen, Beena Pappen, James Burke, Daiju Ichimaru, Yasuo Urata, Toshiyoshi Fujiwara Molecular therapy : the journal of the American Society of Gene Therapy 2010 new
Mutation in the catalytic subunit of DNA polymerase alpha influences transcriptional gene silencing and homologous recombination in Arabidopsis. Jianhua Liu, Xiaozhi Ren, Haibo Yin, Yu Wang, Ran Xia, Youqun Wang, Zhizhong Gong Plant J 2010 new
Reverse transcriptase in motion: conformational dynamics of enzyme-substrate interactions. Matthias Götte, Jason W Rausch, Bruno Marchand, Stefan G Sarafianos, Stuart F J Le Grice Biochimica et biophysica acta 2010 pols set
Differential gene expression by fiber-optic beadarray and pathway in adrenocorticotrophin-secreting pituitary adenomas. Zhi-Quan Jiang, Song-Bo Gui, Ya-Zhuo Zhang Chinese medical journal 2010 new
Study on steady-state kinetics of nucleotide analogues incorporation by non-gel CE. Wujie Li, Mou Cao, Lu Pei, Xiaomei Ling, Bingchao Li, Zhenjun Yang Electrophoresis 2010 partial results
Probing the interaction of archaeal DNA polymerases with deaminated bases using X-ray crystallography and non-hydrogen bonding isosteric base analogues. Tom Killelea, Samantak Ghosh, Samuel S Tan, Pauline Heslop, Susan J Firbank, Eric T Kool, Bernard A Connolly Biochemistry 2010 topics set
Biochemical properties and PCR performance of a family B DNA polymerase from hyperthermophilic Euryarchaeon Thermococcus peptonophilus. Jong Il Lee, Yun Jae Kim, Heejin Bae, Sung Suk Cho, Jung-Hyun Lee, Suk-Tae Kwon Appl Biochem Biotechnol 2010 new
Halogenated beta,gamma-methylene- and ethylidene-dGTP-DNA ternary complexes with DNA polymerase beta: structural evidence for stereospecific binding of the fluoromethylene analogues. Vinod K Batra, Lars C Pedersen, William A Beard, Samuel H Wilson, Boris A Kashemirov, Thomas G Upton, Myron F Goodman, Charles E McKenna Journal of the American Chemical Society 2010 topics set
HIV-1 Ribonuclease H: Structure, Catalytic Mechanism and Inhibitors. Greg L Beilhartz, Matthias Götte Viruses 2010 pols set
DNA polymerases beta and lambda bypass thymine glycol in gapped DNA structures. Ekaterina A Belousova, Giovanni Maga, Yang Fan, Elena A Kubareva, Elena A Romanova, Natalia A Lebedeva, Tatiana S Oretskaya, Olga I Lavrik Biochemistry 2010 new
N348I in HIV-1 reverse transcriptase can counteract the nevirapine-mediated bias toward RNase H cleavage during plus-strand initiation. Mia J Biondi, Greg L Beilhartz, Suzanne McCormick, Matthias Götte The Journal of biological chemistry 2010 pols set
Construction and validation of a yeast model system for studying in vivo the susceptibility to nucleoside analogues of DNA polymerase gamma allelic variants. Enrico Baruffini, Tiziana Lodi Mitochondrion 2010 complete Enrico Baruffini*
Epidemiological and biological evidence for a compensatory effect of connection domain mutation N348I on M184V in HIV-1 reverse transcriptase. Viktor von Wyl, Maryam Ehteshami, Jori Symons, Philippe Bürgisser, Monique Nijhuis, Lisa M Demeter, Sabine Yerly, Jürg Böni, Thomas Klimkait, Rob Schuurman, Bruno Ledergerber, Matthias Götte, Huldrych F Günthard The Journal of infectious diseases 2010 pols set
Structures of DNA polymerases caught processing size-augmented nucleotide probes. Karin Betz, Frank Streckenbach, Andreas Schnur, Thomas Exner, Wolfram Welte, Kay Diederichs, Andreas Marx Angew Chem Int Ed Engl 2010 topics set
HIV-1 RT Inhibitors with a Novel Mechanism of Action: NNRTIs that Compete with the Nucleotide Substrate. Giovanni Maga, Marco Radi, Marie-Aline Gerard, Maurizio Botta, Eric Ennifar Viruses 2010 pols set
Regulation of translesion synthesis DNA polymerase eta by monoubiquitination. Marzena Bienko, Catherine M Green, Simone Sabbioneda, Nicola Crosetto, Ivan Matic, Richard G Hibbert, Tihana Begovic, Atsuko Niimi, Matthias Mann, Alan R Lehmann, Ivan Dikic Molecular cell 2010 new
HIV-1 reverse transcriptase connection domain mutations: dynamics of emergence and implications for success of combination antiretroviral therapy. Viktor von Wyl, Maryam Ehteshami, Lisa M Demeter, Philippe Bürgisser, Monique Nijhuis, Jori Symons, Sabine Yerly, Jürg Böni, Thomas Klimkait, Rob Schuurman, Bruno Ledergerber, Matthias Götte, Huldrych F Günthard Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2010 pols set
Interaction of the human cytomegalovirus uracil DNA glycosylase UL114 with the viral DNA polymerase catalytic subunit UL54. Blair L Strang, Donald M Coen The Journal of general virology 2010 new
DNA polymerase beta-dependent long patch base excision repair in living cells. Kenjiro Asagoshi, Yuan Liu, Aya Masaoka, Li Lan, Rajendra Prasad, Julie K Horton, Ashley R Brown, Xiao-Hong Wang, Hussam Moh'd Bdour, Robert W Sobol, John-Stephen Taylor, Akira Yasui, Samuel H Wilson DNA repair 2010 pols set
Residue 752 in DNA polymerase of equine herpesvirus type 1 is non-essential for virus growth in vitro. Guanggang Ma, Chengping Lu, Nikolaus Osterrieder The Journal of general virology 2010 new
Mitochondrial DNA polymerase POLIB is essential for minicircle DNA replication in African trypanosomes. David F Bruhn, Brian Mozeleski, Laurie Falkin, Michele M Klingbeil Molecular microbiology 2010 new
Parp1 activation in mouse embryonic fibroblasts promotes Pol beta-dependent cellular hypersensitivity to alkylation damage. Elena Jelezcova, Ram N Trivedi, Xiao-Hong Wang, Jiang-bo Tang, Ashley R Brown, Eva M Goellner, S Schamus, JL Fornsaglio, Robert W Sobol Mutation research 2010 complete Robert W Sobol*
DNA polymerases beta and lambda mediate overlapping and independent roles in base excision repair in mouse embryonic fibroblasts. Elena K Braithwaite, Padmini S Kedar, Deborah J Stumpo, Barbara Bertocci, Jonathan H Freedman, Leona D Samson, Samuel H Wilson PloS one 2010 new
Identification of critical residues for the tight binding of both correct and incorrect nucleotides to human DNA polymerase lambda. Jessica A Brown, Lindsey R Pack, Shanen M Sherrer, Ajay K Kshetry, Sean A Newmister, Jason D Fowler, John-Stephen Taylor, Zucai Suo Journal of molecular biology 2010 pols set
DNA polymerase POLN participates in cross-link repair and homologous recombination. George-Lucian Moldovan, Mahesh V Madhavan, Kanchan D Mirchandani, Ryan M McCaffrey, Patrizia Vinciguerra, Alan D D'Andrea Molecular and cellular biology 2010 new
Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4. Jimson H Y Wong, Jessica A Brown, Zucai Suo, Paul Blum, Takehiko Nohmi, Hong Ling The EMBO journal 2010 topics set
Replication factor C recruits DNA polymerase delta to sites of nucleotide excision repair but is not required for PCNA recruitment. René M Overmeer, Audrey M Gourdin, Ambra Giglia-Mari, Hanneke Kool, Adriaan B Houtsmuller, Gregg Siegal, Maria I Fousteri, Leon H F Mullenders, Wim Vermeulen Molecular and cellular biology 2010 new
Hinge residue I174 is critical for proper dNTP selection by DNA polymerase beta. Jen Yamtich, Daniela Starcevic, Julia M Lauper, Elenoe Smith, Idina Shi, Sneha Rangarajan, Joachim Jaeger, Joann B Sweasy Biochemistry 2010 partial results
Accurate DNA synthesis by Sulfolobus solfataricus DNA polymerase B1 at high temperature. Likui Zhang, Huiqiang Lou, Li Guo, Zhengyan Zhan, Zhenhong Duan, Xin Guo, Li Huang Extremophiles 2010 pols set
Functional analysis of H. sapiens DNA polymerase gamma spacer mutation W748S with and without common variant E1143G. Eino J H Palin, Annamari Lesonen, Carol L Farr, Liliya Euro, Anu Suomalainen, Laurie S Kaguni Biochimica et biophysica acta 2010 pols set
Nature, position, and frequency of mutations made in a single cycle of HIV-1 replication. Michael E Abram, Andrea L Ferris, Wei Shao, W Gregory Alvord, Stephen H Hughes Journal of virology 2010 topics set
In search of a selective therapy of viral infections. Erik De Clercq Antiviral research 2010 pols set
Pirh2 E3 ubiquitin ligase targets DNA polymerase eta for 20S proteasomal degradation. Yong-Sam Jung, Gang Liu, Xinbin Chen Molecular and cellular biology 2010 topics set
A 'DNA replication' signature of progression and negative outcome in colorectal cancer. Marie-Jeanne Pillaire, Janick Selves, K Gordien, P-A Gourraud, P-A Gouraud, Catherine Gentil, M Danjoux, C Do, V Negre, Anne Bieth, R Guimbaud, Didier Trouche, Philippe Pasero, M Méchali, Jean-Sébastien Hoffmann, Christophe Cazaux Oncogene 2010 new
DNA polymerase eta, a key protein in translesion synthesis in human cells. Séverine Cruet-Hennequart, Kathleen Gallagher, Anna M Sokòl, Sangamitra Villalan, Aine M Prendergast, Michael P Carty Subcell Biochem 2010 topics set
Ultrasensitive chemiluminescence quantification of single-nucleotide polymorphisms by using monobase-modified Au and CuS nanoparticles. Caifeng Ding, Zhengqiang Wang, Hua Zhong, Shusheng Zhang Biosensors & bioelectronics 2010 new
The relationship between the molecular structure of natural acetogenins and their inhibitory activities which affect DNA polymerase, DNA topoisomerase and human cancer cell growth. Yuki Matsui, Toshifumi Takeuchi, Yuko Kumamoto-Yonezawa, Masaharu Takemura, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Experimental and therapeutic medicine 2010 new
Electrochemical detection of beta-1,3-glucanase gene from transgenic capsicums using asymmetric PCR generated by a detecting probe and an anchoring probe. Guofan Wu, Zhengqiang Wang, Huini Zhang, Ning Yang, Jie Du, Xiaoqing Lu, Jingwan Kang Journal of biotechnology 2010 new
Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex. Eric B Lansdon, Dharmaraj Samuel, Leanna Lagpacan, Katherine M Brendza, Kirsten L White, Magdeleine Hung, Xiaohong Liu, Constantine G Boojamra, Richard L Mackman, Tomas Cihlar, Adrian S Ray, Mary E McGrath, S Swaminathan Journal of molecular biology 2010 complete Eric B Lansdon*
Backbone assignment of the catalytic core of a Y-family DNA polymerase. Dejian Ma, Jason D Fowler, Chunhua Yuan, Zucai Suo Biomol NMR Assign 2010 topics set
Phosphorylated Rad 18 directs DNA Polymerase {eta} to sites of stalled replication. Tovah A Day, Komariah Palle, Laura R Barkley, Naoko Kakusho, Ying Zou, Satoshi Tateishi, Alain Verreault, Hisao Masai, Cyrus Vaziri J Cell Biol 2010 pols set
Evolutionary conservation of residues in vertebrate DNA polymerase N conferring low fidelity and bypass activity. Kei-ichi Takata, Mercedes E Arana, Masayuki Seki, Thomas A Kunkel, Richard D Wood Nucleic acids research 2010 complete Richard D Wood*
The molecular chaperone Hsp90 regulates accumulation of DNA polymerase eta at replication stalling sites in UV-irradiated cells. Takayuki Sekimoto, Tsukasa Oda, Franklin Mayca Pozo, Yoshiki Murakumo, Chikahide Masutani, Fumio Hanaoka, Takayuki Yamashita Molecular cell 2010 topics set
POLD2 and KSP37 (FGFBP2) correlate strongly with histology, stage and outcome in ovarian carcinomas. Bente Vilming Elgaaen, Kari Bente Foss Haug, Junbai Wang, Ole Kristoffer Olstad, Dario Fortunati, Mathias Onsrud, Anne Cathrine Staff, Torill Sauer, Kaare M Gautvik PloS one 2010 new
Effect of oxymatrine on the replication cycle of hepatitis B virus in vitro. Wen-Sheng Xu, Ke-Kai Zhao, Xiao-Hui Miao, Wu Ni, Xiong Cai, Rui-Qi Zhang, Jun-Xue Wang World journal of gastroenterology : WJG 2010 new
[Investigation of the interaction of repair DNA polymerase beta and autonomous 3' --> 5'-exonucleases TREX1 and TREX2]. N V Beliakova, O K Legina, N L Ronzhina, Igor V Shevelev, V M Krutiakov Izv Akad Nauk Ser Biol 2010 new
Ubiquitin-dependent regulation of translesion polymerases. AbelCS Chun, Dong-Yan Jin Biochemical Society transactions 2010 topics set
Translesion DNA synthesis polymerases in DNA interstrand crosslink repair. TheVinh Ho, OrlandoD Schärer Environmental and molecular mutagenesis 2010 topics set
DNA structure and the Werner protein modulate human DNA polymerase delta-dependent replication dynamics within the common fragile site FRA16D. Sandeep N Shah, Patricia L Opresko, Xiao Meng, Marietta Y W T Lee, Kristin A Eckert Nucleic acids research 2010 pols set
Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase. Samra Obeid, Anna Baccaro, Wolfram Welte, Kay Diederichs, Andreas Marx Proceedings of the National Academy of Sciences of the United States of America 2010 complete Andreas Marx*
Characterization of physical and functional interactions between eukaryote-like Orc1/Cdc6 proteins and Y-family DNA polymerase in the hyperthermophilic archaeon Sulfolobus solfataricus. Shifan Yang, Hongchao Gong, Lu Zhang, Yi Liu, Zheng-Guo He Biochem Biophys Res Commun 2010 new
Purified canola lutein selectively inhibits specific isoforms of mammalian DNA polymerases and reduces inflammatory response. Sho Horie, Chiaki Okuda, Takatoshi Yamashita, Kenichi Watanabe, Kouji Kuramochi, Masashi Hosokawa, Toshifumi Takeuchi, Makiko Kakuda, Kazuo Miyashita, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Lipids 2010 new
Opposite effect of two cytomegalovirus DNA polymerase mutations on replicative capacity and polymerase activity. Mélanie Martin, Arezki Azzi, Sheng-Xiang Lin, Guy Boivin Antivir Ther 2010 new
Mutational clusters generated by non-processive polymerases: A case study using DNA polymerase betain vitro. Libertad García-Villada, John W Drake DNA repair 2010 new
Kinetic basis of nucleotide selection employed by a protein template-dependent DNA polymerase. Jessica A Brown, Jason D Fowler, Zucai Suo Biochemistry 2010 new
The acyclic 2,4-diaminopyrimidine nucleoside phosphonate acts as a purine mimetic in HIV-1 reverse transcriptase DNA polymerization. Brian D Herman, Ivan Votruba, Antonin Holy, Nicolas Sluis-Cremer, Jan Balzarini The Journal of biological chemistry 2010 pols set
Bioactive triterpenoids from Kadsura heteroclita. Li-Jia Xu, Zong-Gen Peng, Hong-Shan Chen, Jie Wang, Pei-Gen Xiao Chemistry & biodiversity 2010 pols set
DNA conformational changes at the primer-template junction regulate the fidelity of replication by DNA polymerase. Kausiki Datta, Neil P Johnson, Peter H von Hippel Proceedings of the National Academy of Sciences of the United States of America 2010 new
Novel 1,3-dihydro-benzimidazol-2-ones and their analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. Anna-Maria Monforte, Patrizia Logoteta, Laura De Luca, Nunzio Iraci, Stefania Ferro, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri Bioorganic & medicinal chemistry 2010 pols set
Thioredoxin suppresses microscopic hopping of T7 DNA polymerase on duplex DNA. Candice M Etson, Samir M Hamdan, Charles C Richardson, Antoine M van Oijen Proceedings of the National Academy of Sciences of the United States of America 2010 pols set
[Analysis of mutations in DNA polymerase and thymidine kinase genes of herpes simplex virus clinical isolates resistant to antiherpetic drugs]. A N Korovina, A A Gus'kova, M Iu Skoblov, V L Andronova, G A Galegov, S N Kochetkov, M K Kukhanova, Iu S Skoblov Mol Biol (Mosk) 2010 new
phi29 DNA polymerase active site: role of residue Val250 as metal-dNTP complex ligand and in protein-primed initiation. Patricia Pérez-Arnaiz, José María Lázaro, Margarita Salas, Miguel de Vega Journal of molecular biology 2010 topics set
Structural basis for the suppression of skin cancers by DNA polymerase eta. Timothy D Silverstein, Robert E Johnson, Rinku Jain, Louise Prakash, Satya Prakash, Aneel K Aggarwal Nature 2010 topics set
Improvement of phi29 DNA polymerase amplification performance by fusion of DNA binding motifs. Miguel de Vega, José María Lázaro, Mario Mencía, Luis Blanco, Margarita Salas Proceedings of the National Academy of Sciences of the United States of America 2010 pols set
An alternative pathway for Okazaki fragment processing: resolution of fold-back flaps by Pif1 helicase. JasonE Pike, RyanA Henry, PeterMJ Burgers, JudithL Campbell, RobertA Bambara The Journal of biological chemistry 2010 new
1,2,3-thiadiazole thioacetanilides. Part 2: Synthesis and biological evaluation of a new series of 2-{[4-(3,4-dichlorophenyl)-1,2,3-thiadiazol-5-yl]sulfanyl}acetanilides as HIV-1 inhibitors. Peng Zhan, Xin-Yong Liu, Zhen-Yu Li, Zeng-Jun Fang, Christophe Pannecouque, Erik De Clercq Chemistry & biodiversity 2010 pols set
DNA polymerase eta lacking the ubiquitin-binding domain promotes replicative lesion bypass in humans cells. Narottam Acharya, Jung-Hoon Yoon, Jerard Hurwitz, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2010 new
Error-free replicative bypass of thymine glycol by the combined action of DNA polymerases kappa and zeta in human cells. Jung-Hoon Yoon, G Bhatia, Satya Prakash, Louise Prakash Proceedings of the National Academy of Sciences of the United States of America 2010 topics set
DNA polymerase-beta is required for 1-methyl-4-phenylpyridinium-induced apoptotic death in neurons. Zhentao Zhang, Xuebing Cao, Nian Xiong, Hongcai Wang, Jinsha Huang, Shenggang Sun, Zhihou Liang, Tao Wang Apoptosis 2010 new
Molecular characterization of a distinct begomovirus species from Vernonia cinerea and its associated DNA-beta using the bacteriophage Phi 29 DNA polymerase. R M Packialakshmi, N Srivastava, K R Girish, R Usha Virus genes 2010 new
DNA polymerase beta ribonucleotide discrimination: insertion, misinsertion, extension, and coding. Nisha A Cavanaugh, William A Beard, Samuel H Wilson The Journal of biological chemistry 2010 new
Effect of 8-oxoguanine and abasic site DNA lesions on in vitro elongation by human DNA polymerase in the presence of replication protein A and proliferating-cell nuclear antigen. Giada A Locatelli, Helmut Pospiech, Nicolas Tanguy Le Gac, Barbara van Loon, Ulrich Hubscher, Sinikka Parkkinen, Juhani E Syväoja, Giuseppe Villani Biochem J 2010 new
Characteristics of hepatic igf-ii expression and monitored levels of circulating igf-ii mRNA in metastasis of hepatocellular carcinoma. Jing Qian, Dengfu Yao, Zhizhen Dong, Wei Wu, Liwei Qiu, Ninghua Yao, Shanshan Li, Yinzhu Bian, Zhengqiang Wang, Gongsheng Shi American journal of clinical pathology 2010 new
Expression changes in DNA repair enzymes and mitochondrial DNA damage in aging rat lens. Yongqing Zhang, Lu Zhang, Lan Zhang, Jie Bai, Hongyan Ge, Ping Liu Molecular vision 2010 new
Enhancement of human cancer cell radiosensitivity by conjugated eicosapentaenoic acid - a mammalian DNA polymerase inhibitor. Yuko Kumamoto-Yonezawa, Ryohei Sasaki, Yoko Suzuki, Yuki Matsui, Takahiko Hada, Keisuke Uryu, Kazuro Sugimura, Hiromi Yoshida, Yoshiyuki Mizushina Int J Oncol 2010 pols set
Continued primer synthesis at stalled replication forks contributes to checkpoint activation. Christopher Van, Shan Yan, W Matthew Michael, Shou Waga, Karlene A Cimprich J Cell Biol 2010 complete Karlene A Cimprich*
Human replicative DNA polymerase δ can bypass T-T (6-4) ultraviolet photoproducts on template strands. Takeo Narita, Toshiki Tsurimoto, Junpei Yamamoto, Kana Nishihara, Kaori Ogawa, Eiji Ohashi, Terry Evans, Shigenori Iwai, Shunichi Takeda, Kouji Hirota Genes to cells : devoted to molecular & cellular mechanisms 2010 complete Kouji Hirota*
Association of human cytomegalovirus proteins IRS1 and TRS1 with the viral DNA polymerase accessory subunit UL44. Blair L Strang, Adam P Geballe, Donald M Coen The Journal of general virology 2010 new
Host-specific replication of BK virus DNA in mouse cell extracts is independently controlled by DNA polymerase alpha-primase and inhibitory activities. Irina Tikhanovich, Heinz Peter Nasheuer J Virol 2010 new
Unwinding of zinc finger domain of DNA polymerase I by cis-diamminedichloroplatinum(II). Leila Maurmann, Rathindra N Bose Dalton Trans 2010 new
Replication through an abasic DNA lesion: structural basis for adenine selectivity. Samra Obeid, Nina Blatter, Ramon Kranaster, Andreas Schnur, Kay Diederichs, Wolfram Welte, Andreas Marx The EMBO journal 2010 topics set
Attomole detection of mesophilic DNA polymerase products by nanoparticle-enhanced surface plasmon resonance imaging on glassified gold surfaces. Lida K Gifford, Iuliana E Sendroiu, Robert M Corn, Andrej Lupták Journal of the American Chemical Society 2010 new
Incorporation of gemcitabine and cytarabine into DNA by DNA polymerase beta and ligase III/XRCC1. A S Prakasha Gowda, Joanna M Polizzi, Kristin A Eckert, Thomas E Spratt Biochemistry 2010 new
The C8-2'-deoxyguanosine adduct of 2-amino-3-methylimidazo[1,2-d]naphthalene, a carbocyclic analogue of the potent mutagen 2-amino-3-methylimidazo[4,5-f]quinoline, is a block to replication in vitro. Plamen P Christov, Goutam Chowdhury, Craig A Garmendia, Feng Wang, James S Stover, C Eric Elmquist, Albena Kozekova, Karen C Angel, Robert J Turesky, Michael P Stone, F Peter Guengerich, Carmelo J Rizzo Chemical research in toxicology 2010 pols set
Characterisation of a DNA polymerase highly mutated along the template binding interface. Sophie Vichier-Guerre, Jean-Luc Jestin Mol Biotechnol 2010 pols set
Characterization of a Y-Family DNA Polymerase eta from the Eukaryotic Thermophile Alvinella pompejana. Sayo Kashiwagi, Isao Kuraoka, Yoshie Fujiwara, Kenichi Hitomi, Quen J Cheng, Jill O Fuss, David S Shin, Chikahide Masutani, John A Tainer, Fumio Hanaoka, Shigenori Iwai Journal of nucleic acids 2010 pols set
Lersivirine: a Non-Nucleoside Reverse Transcriptase Inhibitor with Activity against Drug-Resistant Human Immunodeficiency Virus-1. Romuald Corbau, Julie Mori, Chris Phillips, Lesley Fishburn, Alex Martin, Charles Mowbray, Wendy Panton, Caroline Smith-Burchnell, Adele Thornberry, Heather Ringrose, Thorsten Knöchel, Steve Irving, Mike Westby, Anthony Wood, Manos Perros Antimicrob Agents Chemother 2010 complete Romuald Corbau*
The p12 subunit of human polymerase delta modulates the rate and fidelity of DNA synthesis. Xiao Meng, Yanjiao Zhou, Ernest Y C Lee, Marietta Y W T Lee, David N Frick Biochemistry 2010 pols set
Contributions of nucleotide excision repair, DNA polymerase eta, and homologous recombination to replication of UV-irradiated herpes simplex virus type 1. Isabella Muylaert, Per Elias The Journal of biological chemistry 2010 new
Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine. Barbara van Loon, Enni Markkanen, Ulrich Hübscher DNA repair 2010 new
Genetic insertions and diversification of the PolB-type DNA polymerase (gp43) of T4-related phages. Vasiliy M Petrov, Swarnamala Ratnayaka, Jim D Karam Journal of molecular biology 2010 complete Vasiliy M Petrov*
Regulation of DNA polymerase POLD4 influences genomic instability in lung cancer. Qin Miao Huang, Shuta Tomida, Yuji Masuda, Chinatsu Arima, Ke Cao, Taka-Aki Kasahara, Hirotaka Osada, Yasushi Yatabe, Tomohiro Akashi, Kenji Kamiya, Tomonori Takahashi, Motoshi Suzuki Cancer research 2010 new
Structure of the 1,N(2)-etheno-2'-deoxyguanosine lesion in the 3'-G(epsilon dG)T-5' sequence opposite a one-base deletion. Ganesh Shanmugam, Ivan D Kozekov, F Peter Guengerich, Carmelo J Rizzo, Michael P Stone Biochemistry 2010 new
A specific docking site for DNA polymerase {alpha}-primase on the SV40 helicase is required for viral primosome activity, but helicase activity is dispensable. Hao Huang, Kun Zhao, Diana R Arnett, Ellen Fanning The Journal of biological chemistry 2010 new
Modeling DNA polymerase μ motions: subtle transitions before chemistry. Yingqian Li, Tamar Schlick Biophysical journal 2010 topics set
Purification and functional characterization of human mitochondrial DNA polymerase gamma harboring disease mutations. Rajesh Kasiviswanathan, Matthew J Longley, Matthew J Young, William C Copeland Methods 2010 new
UmuD(2) inhibits a non-covalent step during DinB-mediated template slippage on homopolymeric nucleotide runs. James J Foti, Angela M DeLucia, Catherine M Joyce, Graham C Walker The Journal of biological chemistry 2010 new
Molecular analyses of an unusual translesion DNA polymerase from Methanosarcina acetivorans C2A. Li-Jung Lin, Aya Yoshinaga, Yuyen Lin, Claudia Guzman, Yi-Hsing Chen, Shou Mei, Angelica M Lagunas, Satoshi Koike, Shigenori Iwai, M Ashley Spies, Satish K Nair, Roderick I Mackie, Yoshizumi Ishino, Isaac K O Cann Journal of molecular biology 2010 new
Site-directed chemical modification of archaeal Thermococcus litoralis Sh1B DNA polymerase: Acquired ability to read through template-strand uracils. Edita Gaidamaviciute, Daiva Tauraite, Julius Gagilas, Arunas Lagunavicius Biochimica et biophysica acta 2010 pols set
Processing of lagging-strand intermediates in vitro by herpes simplex virus type 1 DNA polymerase. Yali Zhu, Zetang Wu, M Cristina Cardoso, Deborah S Parris J Virol 2010 new
Inhibitory effects of docosyl p-coumarate on DNA topoisomerase activity and human cancer cell growth. Yoshiyuki Mizushina, Katsumi Nishimura, Yukiko Takenaka, Toshifumi Takeuchi, Fumio Sugawara, Hiromi Yoshida, Takao Tanahashi International journal of oncology 2010 new
β-Sitosteryl (6'-O-linoleoyl)-glucoside of soybean (Glycine max L.) crude extract inhibits Y-family DNA polymerases. Sho Horie, Chiaki Okuda, Takatoshi Yamashita, Kenichi Watanabe, Yoshihiro Sato, Yasuhiro Yamaguchi, Toshifumi Takeuchi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Journal of oleo science 2010 new
Only one ATP-binding DnaX subunit is required for initiation complex formation by the Escherichia coli DNA polymerase III holoenzyme. Anna Wieczorek, Christopher D Downey, H Garry Dallmann, Charles S McHenry The Journal of biological chemistry 2010 pols set
Kinetic basis of sugar selection by a Y-family DNA polymerase from Sulfolobus solfataricus P2. Shanen M Sherrer, David C Beyer, Cynthia X Xia, Jason D Fowler, Zucai Suo Biochemistry 2010 pols set
Computational delineation of the catalytic step of a high-fidelity DNA polymerase. Ravindra Venkatramani, Ravi Radhakrishnan Protein science : a publication of the Protein Society 2010 new
Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy. Jingsong Yang, J Parsons, Nils H Nicolay, S Caporali, C F Harrington, R Singh, D Finch, S D'Atri, P B Farmer, P G Johnston, W Gillies McKenna, G Dianov, Ricky A Sharma Oncogene 2010 new
Measurement of kinetic parameters of human platelet DNA polymerase gamma. Jan-Willem Taanman, Margit Heiske, Thierry Letellier Methods 2010 new
Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity. Zhigang Guo, Li Zheng, Huifang Dai, Mian Zhou, Hong Xu, Binghui Shen Nucleic acids research 2009 pols set
Enzymatic synthesis of perfluoroalkylated DNA. Bastian Holzberger, Andreas Marx Bioorganic & medicinal chemistry 2009 new
Treatment of injured neurons with bone marrow stem cells cotransfected by hTERT and Ad-BDNF in vitro. Zhengqiang Wang, Quanjun Deng, Xiaohui Zhang, Jianning Zhang Journal of molecular neuroscience : MN 2009 new
Steric constraints dependent on nucleobase pair orientation vary in different DNA polymerase active sites. Frank Streckenbach, Gopinath Rangam, Heiko M Möller, Andreas Marx Chembiochem 2009 new
Synthesis and structure-activity relationships of dehydroaltenusin derivatives as selective DNA polymerase alpha inhibitors. Kouji Kuramochi, Keishi Fukudome, Isoko Kuriyama, Toshifumi Takeuchi, Yoshihiro Sato, Shinji Kamisuki, Kazunori Tsubaki, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Bioorg Med Chem 2009 pols set
Interaction of human DNA polymerase alpha and DNA polymerase I from Bacillus stearothermophilus with hypoxanthine and 8-oxoguanine nucleotides. Jennifer N Patro, Milan Urban, Robert D Kuchta Biochemistry 2009 pols set
Ctf4 coordinates the progression of helicase and DNA polymerase alpha. Hiromichi Tanaka, Yuki Katou, Masaru Yagura, Katsuya Saitoh, Takehiko Itoh, Hiroyuki Araki, Masashige Bando, Katsuhiko Shirahige Genes Cells 2009 new
Identifying the features of purine dNTPs that allow accurate and efficient DNA replication by herpes simplex virus I DNA polymerase. Nisha A Cavanaugh, Milan Urban, Jeffrey Beckman, Thomas E Spratt, Robert D Kuchta Biochemistry 2009 new
Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase iota. Kevin N Kirouac, Hong Ling The EMBO journal 2009 topics set
3D architecture of DNA Pol alpha reveals the functional core of multi-subunit replicative polymerases. Sebastian Klinge, Rafael Núñez-Ramírez, Oscar Llorca, Luca Pellegrini The EMBO journal 2009 topics set
Mutation Rates and Intrinsic Fidelity of Retroviral Reverse Transcriptases L Menéndez-Arias Viruses 2009 complete ? ?*
Ubiquitin-binding motif of human DNA polymerase eta is required for correct localization. Simone Sabbioneda, Catherine M Green, Marzena Bienko, Patricia L Kannouche, Ivan Dikic, Alan R Lehmann Proceedings of the National Academy of Sciences of the United States of America 2009 complete Alan R Lehmann*
Translesion synthesis of abasic sites by yeast DNA polymerase epsilon. Nasim Sabouri, Erik Johansson The Journal of biological chemistry 2009 new
The accessory subunit of mitochondrial DNA polymerase gamma determines the DNA content of mitochondrial nucleoids in human cultured cells. M Di Re, H Sembongi, J He, Aurelio Reyes, T Yasukawa, P Martinsson, Laura J Bailey, Steffi Goffart, J D Boyd-Kirkup, T S Wong, A R Fersht, Johannes N Spelbrink, Ian J Holt Nucleic acids research 2009 new
Role of Escherichia coli DNA polymerase I in chromosomal DNA replication fidelity. Karolina Makiela-Dzbenska, Malgorzata Jaszczur, Magdalena Banach-Orlowska, Piotr Jonczyk, Roel M Schaaper, I Fijalkowska Molecular microbiology 2009 pols set
Gastrointestinal hyperplasia with altered expression of DNA polymerase beta. Katsuhiko Yoshizawa, Elena Jelezcova, Ashley R Brown, Julie F Foley, Abraham Nyska, Xiangli Cui, Lorne J Hofseth, Robert M Maronpot, Samuel H Wilson, Antonia R Sepulveda, Robert W Sobol PloS one 2009 new
Disruption of mitochondrial DNA replication in Drosophila increases mitochondrial fast axonal transport in vivo. Rehan M Baqri, Brittany A Turner, Mary B Rheuben, Bradley D Hammond, Laurie S Kaguni, Kyle E Miller PloS one 2009 complete Rehan M Baqri*
Mechanism of polymerase collision release from sliding clamps on the lagging strand. Roxana E Georgescu, Isabel Kurth, Nina Y Yao, Jelena Stewart, Olga Yurieva, Mike E O'Donnell The EMBO journal 2009 topics set
Involvement of the beta clamp in methyl-directed mismatch repair in vitro. Anna Pluciennik, Vickers Burdett, Olga Lukianova, Mike E O'Donnell, Paul Modrich The Journal of biological chemistry 2009 topics set
Polymerase-tailored variations in the water-mediated and substrate-assisted mechanism for nucleotidyl transfer: insights from a study of T7 DNA polymerase. Liming Wang, Suse Broyde, Yongqing Zhang Journal of molecular biology 2009 pols set
Characterization of DNA polymerase from the hyperthermophilic archaeon Thermococcus marinus and its application to PCR. Heejin Bae, Kee Pum Kim, Jong Il Lee, Jae-Geun Song, Eui-Joon Kil, Joong Su Kim, Suk-Tae Kwon Extremophiles 2009 new
Effect of the human immunodeficiency virus type 1 reverse transcriptase polymorphism Leu-214 on replication capacity and drug susceptibility. MC Puertas, MJ Buzón, A Artese, S Alcaro, L Menéndez-Arias, CF Perno, B Clotet, F Ceccherini-Silberstein, J Martinez-Picado Journal of virology 2009 topics set
Cloning and characterization of a DNA polymerase beta gene from Trypanosoma cruzi. Juan A Venegas, Lena Aslund, Aldo Solari Parasitol Int 2009 topics set
Differential roles for membrane-bound and soluble syndecan-1 (CD138) in breast cancer progression. Viktoriya Nikolova, Chuay-Yeng Koo, Sherif Abdelaziz Ibrahim, Zhengqiang Wang, Dorothe Spillmann, Rita Dreier, Reinhard Kelsch, Jeanett Fischgräbe, Martin Smollich, Laura H Rossi, Walter Sibrowski, Pia Wülfing, Ludwig Kiesel, George W Yip, Matthias Götte Carcinogenesis 2009 new
DinB upregulation is the sole role of the SOS response in stress-induced mutagenesis in Escherichia coli. Rodrigo S Galhardo, Robert Do, Masami Yamada, Errol C Friedberg, P J Hastings, Takehiko Nohmi, Susan M Rosenberg Genetics 2009 topics set
Regulation of DNA polymerase beta by the LMP1 oncoprotein of EBV through the nuclear factor-kappaB pathway. Nathalie Faumont, Christophe Le Clorennec, Pierre Teira, Gauthier Goormachtigh, Jean Coll, Yvan Canitrot, Christophe Cazaux, Jean-Sébastien Hoffmann, Pierre Brousset, Georges Delsol, Jean Feuillard, Fabienne Meggetto Cancer research 2009 new
Dyslipidaemia and Intima-Media Thickness of Carotid Arteries in Thirty-Five HIV/AIDS Patients Receiving Highly Active Antiretroviral Therapy. Xuexiang Zhang, Xueyan Jiang, Hongzhou Lu, Fang Shen, Jiangrong Wang International journal of biomedical science : IJBS 2009 topics set
Coronary microvascular resistance: methods for its quantification in humans. Paul Knaapen, Paolo G Camici, Koen M Marques, Robin Nijveldt, Jeroen J Bax, Nico Westerhof, Marco J W Götte, Michael Jerosch-Herold, Heinrich R Schelbert, Adriaan A Lammertsma, Albert C van Rossum Basic Res Cardiol 2009 new
Structure and activity relationship of monogalactosyl diacylglycerols, which selectively inhibited in vitro mammalian replicative DNA polymerase activity and human cancer cell growth. Yuki Matsui, Takahiko Hada, Naoki Maeda, Yoshihiro Sato, Yasuhiro Yamaguchi, Toshifumi Takeuchi, Masaharu Takemura, Fumio Sugawara, Kengo Sakaguchi, Hiromi Yoshida, Yoshiyuki Mizushina Cancer Lett 2009 pols set
The efficiency and fidelity of 8-oxo-guanine bypass by DNA polymerases delta and eta. Scott D McCulloch, Robert J Kokoska, Parie Garg, Peter M J Burgers, Thomas A Kunkel Nucleic acids research 2009 pols set
Open-system thermodynamic analysis of DNA polymerase fidelity. Field Cady, Hong Qian Phys Biol 2009 new
Involvement of the TPR2 subdomain movement in the activities of phi29 DNA polymerase. Irene Rodríguez, José María Lázaro, Margarita Salas, Miguel de Vega Nucleic acids research 2009 topics set
Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta. Michael K Swan, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Nature structural & molecular biology 2009 topics set
Stroke work or systolic dP/dtmax to evaluate acute response to cardiac resynchronization therapy: are they interchangeable? Gerjan de Roest, Paul Knaapen, Matthias Götte, Thijs Hendriks, Cor P Allaart, Carel C de Cock, Albert C van Rossum Eur J Heart Fail 2009 new
A real-time fluorescence method for enzymatic characterization of specialized human DNA polymerases. Dorjbal Dorjsuren, David M Wilson, William A Beard, John P McDonald, Christopher P Austin, Roger Woodgate, Samuel H Wilson, Anton Simeonov Nucleic acids research 2009 pols set
DNA polymerase epsilon, acetylases and remodellers cooperate to form a specialized chromatin structure at a tRNA insulator. Namrita Dhillon, Jesse Raab, Julie Guzzo, Shawn J Szyjka, Sunil Gangadharan, Oscar M Aparicio, Brenda Andrews, Rohinton T Kamakaka The EMBO journal 2009 new
Lesion bypass of N2-ethylguanine by human DNA polymerase iota. Matthew G Pence, Patrick Blans, Charles N Zink, Thomas Hollis, James C Fishbein, Fred W Perrino The Journal of biological chemistry 2009 topics set
Functional mapping of the fission yeast DNA polymerase delta B-subunit Cdc1 by site-directed and random pentapeptide insertion mutagenesis. Javier Sanchez Garcia, Andrey G Baranovskiy, Elena V Knatko, Fiona C Gray, Tahir H Tahirov, Stuart A MacNeill BMC Mol Biol 2009 new
Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases. Hana Macícková-Cahová, Michal Hocek Nucleic acids research 2009 topics set
A new DNA polymerase I from Geobacillus caldoxylosilyticus TK4: cloning, characterization, and mutational analysis of two aromatic residues. Cemal Sandalli, Kamalendra Singh, Mukund J Modak, Amit Ketkar, Sabriye Canakci, Ismail Demir, Ali Osman Belduz Appl Microbiol Biotechnol 2009 new
Low-fidelity DNA synthesis by the L979F mutator derivative of Saccharomyces cerevisiae DNA polymerase zeta. Jana E Stone, Grace E Kissling, Scott A Lujan, Igor B Rogozin, Carrie M W Stith, Peter M J Burgers, Thomas A Kunkel Nucleic acids research 2009 pols set
Polymerase dynamics at the eukaryotic DNA replication fork. Peter M J Burgers The Journal of biological chemistry 2009 new
Novel application of Phi29 DNA polymerase: RNA detection and analysis in vitro and in situ by target RNA-primed RCA. Arunas Lagunavicius, Egle Merkiene, Zivile Kiveryte, Agne Savaneviciute, Vilma Zimbaite-Ruskuliene, Tomas Radzvilavicius, Arvydas Janulaitis RNA 2009 pols set
Human DNA polymerase theta possesses 5'-dRP lyase activity and functions in single-nucleotide base excision repair in vitro. Rajendra Prasad, Matthew J Longley, Farida S Sharief, Esther W Hou, William C Copeland, Samuel H Wilson Nucleic acids research 2009 pols set
Proofreading exonuclease activity of human DNA polymerase delta and its effects on lesion-bypass DNA synthesis. Ruzaliya Fazlieva, Cynthia S Spittle, Darlene Morrissey, Harutoshi Hayashi, Hong Yan, Yoshihiro Matsumoto Nucleic acids research 2009 pols set
Drug targets in cytomegalovirus infection. Graciella Andrei, Erik De Clercq, Robert Snoeck Infectious disorders drug targets 2009 new
Synthesis and anti-HIV activity evaluation of 2-(4-(naphthalen-2-yl)-1,2,3-thiadiazol-5-ylthio)-N-acetamides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. Peng Zhan, Xinyong Liu, Zengjun Fang, Zhongjie Li, Christophe Pannecouque, Erik De Clercq European journal of medicinal chemistry 2009 pols set
DNA polymerase beta substrate specificity: side chain modulation of the "A-rule". William A Beard, David D Shock, Vinod K Batra, Lars C Pedersen, Samuel H Wilson The Journal of biological chemistry 2009 topics set
Design strategies of novel NNRTIs to overcome drug resistance. Peng Zhan, Xinyong Liu, Zhongjie Li, Christophe Pannecouque, Erik De Clercq Current medicinal chemistry 2009 pols set
1,2,3-Selenadiazole thioacetanilides: synthesis and anti-HIV activity evaluation. Peng Zhan, Xinyong Liu, Zengjun Fang, Christophe Pannecouque, Erik De Clercq Bioorganic & medicinal chemistry 2009 pols set
Anti-HIV drugs: 25 compounds approved within 25 years after the discovery of HIV. Erik De Clercq International journal of antimicrobial agents 2009 pols set
Versatility of Y-family Sulfolobus solfataricus DNA polymerase Dpo4 in translesion synthesis past bulky N2-alkylguanine adducts. Haijiang Zhang, Robert Lawton Eoff, Ivan D Kozekov, Carmelo J Rizzo, Martin Egli, F Peter Guengerich The Journal of biological chemistry 2009 topics set
A light-activated DNA polymerase. Chungjung Chou, Douglas D Young, Alexander Deiters Angew Chem Int Ed Engl 2009 new
Probing conformational changes of human DNA polymerase lambda using mass spectrometry-based protein footprinting. Jason D Fowler, Jessica A Brown, Mamuka Kvaratskhelia, Zucai Suo Journal of molecular biology 2009 pols set
A new drug combination therapy for treatment-naive patients with HIV-1 infection, consisting of raltegravir, emtricitabine and tenofovir disoproxil fumarate. Erik De Clercq Expert opinion on pharmacotherapy 2009 pols set
Characterization of a natural mutator variant of human DNA polymerase lambda which promotes chromosomal instability by compromising NHEJ. Gloria Terrados, Jean-Pascal Capp, Yvan Canitrot, Miguel García-Díaz, Katarzyna Bebenek, Tomas Kirchhoff, Alberto Villanueva, François Boudsocq, Valérie Bergoglio, Christophe Cazaux, Thomas A Kunkel, Jean-Sébastien Hoffmann, Luis Blanco PloS one 2009 pols set
Structural basis for novel interactions between human translesion synthesis polymerases and proliferating cell nuclear antigen. Asami Hishiki, Hiroshi Hashimoto, Tomo Hanafusa, Keijiro Kamei, Eiji Ohashi, Toshiyuki Shimizu, Haruo Ohmori, Mamoru Sato The Journal of biological chemistry 2009 topics set
TopBP1 and DNA polymerase-alpha directly recruit the 9-1-1 complex to stalled DNA replication forks. Shan Yan, W Matthew Michael J Cell Biol 2009 topics set
Characterization of the effects of cisplatin and carboplatin on cell cycle progression and DNA damage response activation in DNA polymerase eta-deficient human cells. Séverine Cruet-Hennequart, Sangamitra Villalan, Agnieszka Kaczmarczyk, Elaine O'Meara, Anna M Sokol, Michael P Carty Cell Cycle 2009 new
Translesional DNA synthesis through a C8-guanyl adduct of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in Vitro: REV1 inserts dC opposite the lesion, and DNA polymerase kappa potentially catalyzes extension reaction from the 3'-dC terminus. Hirokazu Fukuda, Takeji Takamura-Enya, Yuji Masuda, Takehiko Nohmi, Chiho Seki, Kenji Kamiya, Takashi Sugimura, Chikahide Masutani, Fumio Hanaoka, Hitoshi Nakagama The Journal of biological chemistry 2009 new
C-terminal phenylalanine of bacteriophage T7 single-stranded DNA-binding protein is essential for strand displacement synthesis by T7 DNA polymerase at a nick in DNA. Sharmistha Ghosh, Boriana Marintcheva, Masateru Takahashi, Charles C Richardson The Journal of biological chemistry 2009 pols set
DNA polymerase switching: effects on spontaneous mutagenesis in Escherichia coli. Elena Curti, John P McDonald, Samantha Mead, Roger Woodgate Molecular microbiology 2009 new
Limited terminal transferase in human DNA polymerase mu defines the required balance between accuracy and efficiency in NHEJ. Paula Andrade, María José Martín, Raquel Juárez, Francisco López de Saro, Luis Blanco Proceedings of the National Academy of Sciences of the United States of America 2009 pols set
A novel triple-regulated oncolytic adenovirus carrying PDCD5 gene exerts potent antitumor efficacy on common human leukemic cell lines. Min Xie, Ji-Hong Niu, Yan Chang, Qi-Jun Qian, Hong-Ping Wu, Lin-Fang Li, Yongqing Zhang, Jin-Lan Li, Xiao-Jun Huang, Guo-Rui Ruan Apoptosis : an international journal on programmed cell death 2009 new
RB69 DNA polymerase mutants with expanded nascent base-pair-binding pockets are highly efficient but have reduced base selectivity. Haijiang Zhang, Jeff W Beckman, Jianhong Wang, William H Konigsberg Biochemistry 2009 complete
Structure of HIV-1 reverse transcriptase with the inhibitor beta-Thujaplicinol bound at the RNase H active site. Daniel M Himmel, Karen A Maegley, Tom A Pauly, Joseph David Bauman, Kalyan Das, Chhaya Dharia, Arthur D Clark, Kevin Ryan, Michael J Hickey, Robert A Love, Stephen H Hughes, Simon Bergqvist, Edward Arnold Structure (London, England : 1993) 2009 partial results
SEMG-1 expression in early stage chronic lymphocytic leukemia. Sharif Uddin Ahmed, Farouk Meklat, Masum Shahriar, Jian Zhang, Suhkrob Mastulov, Thomas Giannakouros, Andrew Jewell, Yongqing Zhang, Seah H Lim Cytotherapy 2009 new
Controllable expansion of primary cardiomyocytes by reversible immortalization. Yongqing Zhang, Edem Nuglozeh, Fatouma Touré, Ann Marie Schmidt, Gordana Vunjak-Novakovic Human gene therapy 2009 new
A novel electrochemical biosensor based on dynamic polymerase-extending hybridization for E. coli O157:H7 DNA detection. Lijiang Wang, Qingjun Liu, Zhaoying Hu, Yongqing Zhang, Chunsheng Wu, Mo Yang, Ping Wang Talanta 2009 pols set
The flexible loop of the human cytomegalovirus DNA polymerase processivity factor ppUL44 is required for efficient DNA binding and replication in cells. Gualtiero Alvisi, Daniela Martino Roth, Daria Camozzi, Gregory S Pari, Arianna Loregian, Alessandro Ripalti, David A Jans J Virol 2009 pols set
Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA. Guangxin Xing, Kevin N Kirouac, Yoon Jung Shin, Stephen D Bell, Hong Ling Molecular microbiology 2009 topics set
Unnatural imidazopyridopyrimidine:naphthyridine base pairs: selective incorporation and extension reaction by DNA polymerases. Noriaki Minakawa, Shintaro Ogata, Mayumi Takahashi, Akira Matsuda Nucleic Acids Symp Ser (Oxf) 2009 topics set
Competitive capacity of HIV-1 strains carrying M184I or Y181I drug-resistant mutations. Jinming Li, Lin Li, Han-Ping Li, Dao-Min Zhuang, Si-Yang Liu, Yong-Jian Liu, Zuo-Yi Bao, Zhengqiang Wang, Jing-Yun Li Chinese medical journal 2009 new
Structural basis for the role of the K65R mutation in HIV-1 reverse transcriptase polymerization, excision antagonism, and tenofovir resistance. Kalyan Das, Rajiv P Bandwar, Kirsten L White, Joy Y Feng, Stefan G Sarafianos, Steven Tuske, Xiongying Tu, Arthur D Clark, Paul L Boyer, Xiaorong Hou, Barbara L Gaffney, Roger A Jones, Michael D Miller, Stephen H Hughes, Edward Arnold The Journal of biological chemistry 2009 partial results
Synthesis and in vitro anti-HIV evaluation of a new series of 6-arylmethyl-substituted S-DABOs as potential non-nucleoside HIV-1 reverse transcriptase inhibitors. Yue-Ping Wang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque European journal of medicinal chemistry 2009 pols set
Yeast Rev1 protein promotes complex formation of DNA polymerase zeta with Pol32 subunit of DNA polymerase delta. Narottam Acharya, Robert E Johnson, Vincent Pagès, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2009 new
Archaeal eukaryote-like Orc1/Cdc6 initiators physically interact with DNA polymerase B1 and regulate its functions. Lu Zhang, Lei Zhang, Yi Liu, Shifan Yang, Chunhui Gao, Hongchao Gong, Ying Feng, Zheng-Guo He Proceedings of the National Academy of Sciences of the United States of America 2009 new
The 3'-5' proofreading exonuclease of archaeal family-B DNA polymerase hinders the copying of template strand deaminated bases. Henry J Russell, Tomas T Richardson, Kieran Emptage, Bernard A Connolly Nucleic acids research 2009 partial results
Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. Peng Zhan, Xinyong Liu, Junjie Zhu, Zengjun Fang, Zhongjie Li, Christophe Pannecouque, Erik De Clercq Bioorganic & medicinal chemistry 2009 pols set
Finger domain mutation affects enzyme activity, DNA replication efficiency, and fidelity of an exonuclease-deficient DNA polymerase of herpes simplex virus type 1. Wang Tian, Ying T Hwang, Qiangsheng Lu, Charles B C Hwang J Virol 2009 partial results
Template usage is responsible for the preferential acquisition of the K65R reverse transcriptase mutation in subtype C variants of human immunodeficiency virus type 1. Dimitrios Coutsinos, Cédric F Invernizzi, Hongtao Xu, Daniela D Moisi, Maureen Oliveira, Bluma G Brenner, Mark A. Wainberg Journal of virology 2009 pols set
Apricitabine does not select additional drug resistance mutations in tissue culture in human immunodeficiency virus type 1 variants containing K65R, M184V, or M184V plus thymidine analogue mutations. Maureen Oliveira, Daniela D Moisi, Bonnie Spira, Susan Cox, Bluma G Brenner, Mark A. Wainberg Antimicrobial agents and chemotherapy 2009 new
Amino acid architecture that influences dNTP insertion efficiency in Y-family DNA polymerase V of E. coli. Kwang Young Seo, Jun Yin, Prashant Donthamsetti, Sushil Chandani, Chui Hong Lee, Edward L Loechler Journal of molecular biology 2009 pols set
Effects of the K65R and K65R/M184V reverse transcriptase mutations in subtype C HIV on enzyme function and drug resistance. Hong-Tao Xu, Jorge L Martinez-Cajas, Michel L Ntemgwa, Dimitrios Coutsinos, Fernando A Frankel, Bluma G Brenner, Mark A. Wainberg Retrovirology 2009 new
Non-nucleoside reverse transcriptase inhibitors (Part 18): synthesis and anti-HIV activity of 4-allylamino or 4-azido substituted diaryltriazines. Yuan-Zhen Xiong, Hai-Rong Hu, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq Yao xue xue bao = Acta pharmaceutica Sinica 2009 new
Incorporation of an inducible nucleotide analog into DNA by DNA polymerases. Md Monsur Ali, Shuhei Imoto, Yingqian Li, Shigeki Sasaki, Fumi Nagatsugi Bioorg Med Chem 2009 topics set
Synthesis of alkenyldiarylmethanes (ADAMs) containing benzo[d]isoxazole and oxazolidin-2-one rings, a new series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors. Bo-Liang Deng, Yaofeng Zhao, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman European journal of medicinal chemistry 2009 pols set
Expression of an X-family DNA polymerase, pol lambda, in the respiratory epithelium of non-small cell lung cancer patients with habitual smoking. Taro Ohba, Takurou Kometani, Fumihiro Shoji, Tokujiro Yano, Ichiro Yoshino, Yoshino Ichiro, Kenichi Taguchi, Isao Kuraoka, Shinya Oda, Yoshihiko Maehara Mutation research 2009 new
Signature nucleotide polymorphisms at positions 64 and 65 in reverse transcriptase favor the selection of the K65R resistance mutation in HIV-1 subtype C. Cédric F Invernizzi, Dimitrios Coutsinos, Maureen Oliveira, Daniela D Moisi, Bluma G Brenner, Mark A. Wainberg The Journal of infectious diseases 2009 pols set
Polymerization fidelity of a replicative DNA polymerase from the hyperthermophilic archaeon Sulfolobus solfataricus P2. Likui Zhang, Jessica A Brown, Sean A Newmister, Zucai Suo Biochemistry 2009 topics set
Mutants of Taq DNA polymerase resistant to PCR inhibitors allow DNA amplification from whole blood and crude soil samples. Milko B Kermekchiev, Lyubka I Kirilova, Erika E Vail, Wayne M Barnes Nucleic acids research 2009 pols set
Structural and functional analysis of Sulfolobus solfataricus Y-family DNA polymerase Dpo4-catalyzed bypass of the malondialdehyde-deoxyguanosine adduct. Robert Lawton Eoff, Jennifer B Stafford, Jozsef Szekely, Carmelo J Rizzo, Martin Egli, F Peter Guengerich, Lawrence J Marnett Biochemistry 2009 topics set
DNA polymerase beta reveals enhanced activity and processivity in reverse micelles. Rashid O Anarbaev, Anastasia L Rogozina, Olga I Lavrik Biophys Chem 2009 pols set
The unfolding clinical spectrum of POLG mutations. M J Blok, B J van den Bosch, E Jongen, A Hendrickx, C E de Die-Smulders, J E Hoogendijk, E Brusse, M de Visser, B T Poll-The, J Bierau, I F de Coo, H J Smeets Journal of medical genetics 2009 pols set
Human immunodeficiency virus type 1 recombinant reverse transcriptase enzymes containing the G190A and Y181C resistance mutations remain sensitive to etravirine. Hongtao Xu, Yudong Quan, Bluma G Brenner, Tamara Bar-Magen, Maureen Oliveira, Susan M Schader, Mark A. Wainberg Antimicrobial agents and chemotherapy 2009 pols set
Expression pattern of dmrt4 from olive flounder (Paralichthys olivaceus) in adult gonads and during embryogenesis. Aiyun Wen, Feng You, Xungang Tan, Peng Sun, Jing Ni, Yongqing Zhang, Dongdong Xu, Zhihao Wu, Yongli Xu, Peiming Zhang Fish physiology and biochemistry 2009 new
[Construction and immunoscreening of cDNA library of Babesia orientalis]. Qin Liu, Dan-Na Zhou, Yan-Qin Zhou, Yongqing Zhang, Lan He, Bao-An Yao, Jun-Long Zhao Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 2009 new
Insights into the high fidelity of a DNA polymerase I mutant. Thomas E Exner J Mol Model 2009 pols set
Prevalence of the K65R resistance reverse transcriptase mutation in different HIV-1 subtypes in Israel. Dan Turner, Eduardo Shahar, Eugene Katchman, Eynat Kedem, Natasha Matus, Michal Katzir, Gamal Hassoun, Shimon Pollack, Rivka Kessner, Mark A. Wainberg, Boaz Avidor Journal of medical virology 2009 pols set
Mechanisms associated with HIV-1 resistance to acyclovir by the V75I mutation in reverse transcriptase. Egor P Tchesnokov, Aleksandr Obikhod, Ivana Massud, Andrea Lisco, Christophe Vanpouille, Beda Brichacek, Jan Balzarini, Christopher McGuigan, Marco Derudas, Leonid Margolis, Raymond F Schinazi, Matthias Götte The Journal of biological chemistry 2009 topics set
RNase H active site inhibitors of human immunodeficiency virus type 1 reverse transcriptase: design, biochemical activity, and structural information. Thorsten A Kirschberg, Mini Balakrishnan, Neil H Squires, Tiffany Barnes, Katherine M Brendza, Xiaowu Chen, Eugene J Eisenberg, Weili Jin, Nilima Kutty, Stephanie Leavitt, Albert C Liclican, Qi Liu, Xiaohong Liu, John Mak, Jason K Perry, Michael Wang, William J Watkins, Eric B Lansdon J Med Chem 2009 new
Population-specific variation in haplotype composition and heterozygosity at the POLB locus. Jennifer Yamtich, William C Speed, Eva Straka, Judith R Kidd, Joann B Sweasy, Kenneth K Kidd DNA repair 2009 new
Synthesis and studies of new 2-(coumarin-4-yloxy)-4,6-(substituted)-S-triazine derivatives as potential anti-HIV agents. Dharmesh H Mahajan, Christophe Pannecouque, Erik De Clercq, Kishor H Chikhalia Archiv der Pharmazie 2009 pols set
Discrimination between right and wrong purine dNTPs by DNA polymerase I from Bacillus stearothermophilus. Michael Trostler, Alison Delier, Jeff W Beckman, Milan Urban, Jennifer N Patro, Thomas E Spratt, Lorena S Beese, Robert D Kuchta Biochemistry 2009 topics set
[Research progress on DNA polymerase beta and genetic instability]. Mei Wu, Zhenzhong Zhang Wei sheng yan jiu = Journal of hygiene research 2009 topics set
Expression of herpes simplex virus type 1 DNA polymerase by recombinant vaccinia virus. Ralf Kronenwett, Klaus Weisshart, Charles W Knopf Virus genes 2009 new
Comparative purification strategies for Drosophila and human mitochondrial DNA replication proteins: DNA polymerase gamma and mitochondrial single-stranded DNA-binding protein. Marcos T Oliveira, Laurie S Kaguni Methods in molecular biology (Clifton, N.J.) 2009 new
Investigation of stoichiometry of T4 bacteriophage helicase loader protein (gp59). Sri Ranjini Arumugam, Tae-Hee Lee, Stephen J Benkovic The Journal of biological chemistry 2009 topics set
Structural and functional elucidation of the mechanism promoting error-prone synthesis by human DNA polymerase kappa opposite the 7,8-dihydro-8-oxo-2'-deoxyguanosine adduct. Adriana Irimia, Robert Lawton Eoff, F Peter Guengerich, Martin Egli The Journal of biological chemistry 2009 topics set
Global conformational dynamics of a Y-family DNA polymerase during catalysis. Cuiling Xu, Brian A Maxwell, Jessica A Brown, Likui Zhang, Zucai Suo PLoS Biol 2009 topics set
Highly efficient incorporation of the fluorescent nucleotide analogs tC and tCO by Klenow fragment. Peter Sandin, Gudrun Stengel, Thomas Ljungdahl, Karl Börjesson, Bertil Macao, L Marcus Wilhelmsson Nucleic acids research 2009 partial results
The application of phosphoramidate protide technology to acyclovir confers anti-HIV inhibition. Marco Derudas, Davide Carta, Andrea Brancale, Christophe Vanpouille, Andrea Lisco, Leonid Margolis, Jan Balzarini, Christopher McGuigan Journal of medicinal chemistry 2009 pols set
Single molecule measurement of the "speed limit" of DNA polymerase. Jerrod J Schwartz, Stephen R Quake Proceedings of the National Academy of Sciences of the United States of America 2009 new
Cervical cancer isolate PT3, super-permissive for adeno-associated virus replication, over-expresses DNA polymerase delta, PCNA, RFC and RPA. Bum Yong Kang, Hong You, Sarmistha Bandyopadhyay, Nalini Agrawal, Russell B Melchert, Alexei G Basnakian, Yong Liu, Paul L Hermonat BMC Microbiol 2009 new
Strand displacement by DNA polymerase III occurs through a tau-psi-chi link to single-stranded DNA-binding protein coating the lagging strand template. Quan Yuan, Charles S McHenry The Journal of biological chemistry 2009 new
[Different instability of microsatellite CAG repeat in two groups of haplotypes of the human mitochondrial gamma-DNA-polymerase gene]. B A Maliarchuk, M A Perkova, Miroslava V Derenko Mol Biol (Mosk) 2009 new
Conformational changes during nucleotide selection by Sulfolobus solfataricus DNA polymerase Dpo4. Robert Lawton Eoff, Raymundo Sanchez-Ponce, F Peter Guengerich The Journal of biological chemistry 2009 pols set
Involvement of specialized DNA polymerases in mutagenesis by 8-hydroxy-dGTP in human cells. Kazuya Satou, Mika Hori, Kazuaki Kawai, Hiroshi Kasai, Hideyoshi Harashima, Hiroyuki Kamiya DNA repair 2009 topics set
Mice expressing an error-prone DNA polymerase in mitochondria display elevated replication pausing and chromosomal breakage at fragile sites of mitochondrial DNA. Laura J Bailey, Tricia J Cluett, Aurelio Reyes, Tom A Prolla, Joanna Poulton, Christiaan Leeuwenburgh, Ian J Holt Nucleic acids research 2009 new
Frameshift deletion by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W is selective for purines and involves normal conformational change followed by slow phosphodiester bond formation. Haijiang Zhang, Jeff W Beckman, F Peter Guengerich The Journal of biological chemistry 2009 pols set
PCNA monoubiquitylation and DNA polymerase eta ubiquitin-binding domain are required to prevent 8-oxoguanine-induced mutagenesis in Saccharomyces cerevisiae. Patricia Auffret van der Kemp, Marcelo de Padula, Guenaelle Burguiere-Slezak, Helle D Ulrich, Serge Boiteux Nucleic acids research 2009 new
A DNA polymerase-{alpha}{middle dot}primase cofactor with homology to replication protein A-32 regulates DNA replication in mammalian cells. Darren E Casteel, Shunhui Zhuang, Ying Zeng, Fred W Perrino, Gerry R Boss, Mehran Goulian, Renate B Pilz The Journal of biological chemistry 2009 new
Sulfanyltriazole/tetrazoles: a promising class of HIV-1 NNRTIs. Peng Zhan, Zhongjie Li, Xinyong Liu, Erik De Clercq Mini reviews in medicinal chemistry 2009 pols set
Competitive inhibition of uracil DNA glycosylase by a modified nucleotide whose triphosphate is a substrate for DNA polymerase. Haidong Huang, James T Stivers, Marc M Greenberg Journal of the American Chemical Society 2009 pols set
A historical reflection on the discovery of human retroviruses. Anders Vahlne Retrovirology 2009 topics set
3-O-methylfunicone, a selective inhibitor of mammalian Y-family DNA polymerases from an Australian sea salt fungal strain. Yoshiyuki Mizushina, Hirohisa Motoshima, Yasuhiro Yamaguchi, Toshifumi Takeuchi, Ken Hirano, Fumio Sugawara, Hiromi Yoshida Marine drugs 2009 pols set
The roles of APE1, APE2, DNA polymerase beta and mismatch repair in creating S region DNA breaks during antibody class switch. Carol E Schrader, Jeroen E J Guikema, Xiaoming Wu, Janet Stavnezer Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2009 new
A trimeric DNA polymerase complex increases the native replication processivity. Andrey L Mikheikin, Hsiang-Kai Lin, Preeti Mehta, Linda Jen-Jacobson, Michael A Trakselis Nucleic acids research 2009 partial results
Steric and electrostatic effects at the C2 atom substituent influence replication and miscoding of the DNA deamination product deoxyxanthosine and analogs by DNA polymerases. Huidong Zhang, Urban Bren, Ivan D Kozekov, Carmelo J Rizzo, Donald F Stec, F Peter Guengerich Journal of molecular biology 2009 pols set
Non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 13: synthesis of fluorine-containing diaryltriazine derivatives for in vitro anti-HIV evaluation against wild-type strain. Yuan-Zhen Xiong, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque Chemistry & biodiversity 2009 pols set
An 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase lambda. Barbara van Loon, Ulrich Hübscher Proceedings of the National Academy of Sciences of the United States of America 2009 pols set
Effect of A and B metal ion site occupancy on conformational changes in an RB69 DNA polymerase ternary complex. Michael Wang, Harold R Lee, William H Konigsberg Biochemistry 2009 complete
Plasmid-based lacZalpha assay for DNA polymerase fidelity: application to archaeal family-B DNA polymerase. Stanislaw K Jozwiakowski, Bernard A Connolly Nucleic acids research 2009 topics set
AML1-ETO9a is correlated with C-KIT overexpression/mutations and indicates poor disease outcome in t(8;21) acute myeloid leukemia-M2. B Jiao, C-F Wu, Y Liang, H-M Chen, S-M Xiong, B Chen, J-Y Shi, Y-Y Wang, Jing-Houng Wang, Y Chen, J-M Li, L-J Gu, J-Y Tang, Z-X Shen, B-W Gu, W-L Zhao, Zhiwen Chen, S-J Chen Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2009 new
Design, synthesis, and SAR of naphthyl-substituted Diarylpyrimidines as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Yong-Hong Liang, Xiao-Qing Feng, Zhao-Sen Zeng, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq ChemMedChem 2009 pols set
Effects of ectopic expression of human telomerase reverse transcriptase on immortalization of feather keratinocyte stem cells. Yulin Xu, Minli Yu, Fabai Wu, Jianguo Sun, Chris Wood, Masa-Aki Hattori, Jinfu Wang, Yongmei Xi Journal of experimental zoology. Part B, Molecular and developmental evolution 2009 new
Impact of novel human immunodeficiency virus type 1 reverse transcriptase mutations P119S and T165A on 4'-ethynylthymidine analog resistance profile. Guangwei Yang, Elijah Paintsil, Ginger E Dutschman, Susan P Grill, Chuan-Jen Wang, Jianhong Wang, Hiromichi Tanaka, Takayuki Hamasaki, Masanori Baba, Yung-Chi Cheng Antimicrobial agents and chemotherapy 2009 new
Antitumor effects of targeting hTERT lentivirus-mediated RNA interference against KB cell lines. Dan Chen, Hongzhang Huang, Chaobin Pan, Jianguang Wang, Bin Zhang, Anxun Wang Oncology research 2009 new
Ethanol-tolerant Saccharomyces cerevisiae strains isolated under selective conditions by over-expression of a proofreading-deficient DNA polymerase delta. Hiroko Abe, Yasuko Fujita, Yuki Takaoka, Eri Kurita, Shuntaro Yano, Naotaka Tanaka, Ken-ichi Nakayama J Biosci Bioeng 2009 new
Proofreading dynamics of a processive DNA polymerase. Borja Ibarra, Yann R Chemla, Sergey Plyasunov, Steven B Smith, José María Lázaro, Margarita Salas, Carlos Bustamante The EMBO journal 2009 new
Augmentation of reverse transcription by integrase through an interaction with host factor, SIP1/Gemin2 Is critical for HIV-1 infection. Hironori Nishitsuji, Takaya Hayashi, Tomosaburo Takahashi, Masashi Miyano, Mari Kannagi, Takao Masuda PloS one 2009 complete Takao Masuda*
Mutational analysis of the HIV-1 auxiliary protein Vif identifies independent domains important for the physical and functional interaction with HIV-1 reverse transcriptase. Alexandra Kataropoulou, Chiara Bovolenta, Amalia Belfiore, Sonia Trabatti, Anna Garbelli, Simona Porcellini, Rossella Lupo, Giovanni Maga Nucleic acids research 2009 pols set
Non-nucleoside HIV-1 reverse transcriptase inhibitors di-halo-indolyl aryl sulfones achieve tight binding to drug-resistant mutants by targeting the enzyme-substrate complex. Alberta Samuele, Alexandra Kataropoulou, Marco Viola, Samantha Zanoli, Giuseppe La Regina, Francesco Piscitelli, Romano Silvestri, Giovanni Maga Antiviral research 2009 pols set
Penicilliols A and B, novel inhibitors specific to mammalian Y-family DNA polymerases. Takuma Kimura, Toshifumi Takeuchi, Yuko Kumamoto-Yonezawa, Eiji Ohashi, Haruo Ohmori, Chikahide Masutani, Fumio Hanaoka, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Bioorganic & medicinal chemistry 2009 pols set
Discovery of chiral cyclopropyl dihydro-alkylthio-benzyl-oxopyrimidine (S-DABO) derivatives as potent HIV-1 reverse transcriptase inhibitors with high activity against clinically relevant mutants. Marco Radi, Giovanni Maga, Maddalena Alongi, Lucilla Angeli, Alberta Samuele, Samantha Zanoli, Luca Bellucci, Andrea Tafi, Gianni Casaluce, Gianluca Giorgi, Mercedes Armand-Ugon, Emmanuel Gonzalez, José A Esté, Mireille Baltzinger, Guillaume Bec, Philippe Dumas, Eric Ennifar, Maurizio Botta Journal of medicinal chemistry 2009 pols set
Specific targeting of highly conserved residues in the HIV-1 reverse transcriptase primer grip region. 2. Stereoselective interaction to overcome the effects of drug resistant mutations. Stefania Butini, Margherita Brindisi, Sandro Cosconati, Luciana Marinelli, Giuseppe Borrelli, Salvatore Sanna Coccone, Anna Ramunno, Giuseppe Campiani, Ettore Novellino, Samantha Zanoli, Alberta Samuele, Gianluca Giorgi, Alberto Bergamini, Michela Di Mattia, Silvana Lalli, Bruno Galletti, Sandra Gemma, Giovanni Maga Journal of medicinal chemistry 2009 pols set
Genomic analyses of recombinant adenovirus type 11a in China. Zhaohui Yang, Zhen Zhu, Liuying Tang, Li Wang, Xiaojuan Tan, Pengbo Yu, Yong Zhang, Xiaoping Tian, Jingjun Wang, Yan Ming Zhang, Dexin Li, Wenbo Xu Journal of clinical microbiology 2009 new
Engineering of a chimeric RB69 DNA polymerase sensitive to drugs targeting the cytomegalovirus enzyme. Egor P Tchesnokov, Aleksandr Obikhod, Raymond F Schinazi, Matthias Götte The Journal of biological chemistry 2009 topics set
Direct and indirect roles of RECQL4 in modulating base excision repair capacity. Shepherd H Schurman, Mohammad Hedayati, Zhengqiang Wang, Dharmendra Kumar Singh, Elzbieta Speina, Yongqing Zhang, Kevin Becker, Margaret Macris, Patrick Sung, David M Wilson, Deborah L Croteau, Vilhelm A Bohr Human molecular genetics 2009 new
Molecular analyses of a three-subunit euryarchaeal clamp loader complex from Methanosarcina acetivorans. Yi-Hsing Chen, Yuyen Lin, Aya Yoshinaga, Benazir Chhotani, Jenna L Lorenzini, Alexander A Crofts, Shou Mei, Roderick I Mackie, Yoshizumi Ishino, Isaac K O Cann Journal of bacteriology 2009 new
The crystal structure of PF-8, the DNA polymerase accessory subunit from Kaposi's sarcoma-associated herpesvirus. Jennifer L Baltz, David J Filman, Mihai Ciustea, Janice Elaine Y Silverman, Catherine L Lautenschlager, Donald M Coen, Robert P Ricciardi, James M Hogle J Virol 2009 new
Efficient enzymatic synthesis of LNA-modified DNA duplexes using KOD DNA polymerase. Rakesh N Veedu, Birte Vester, Jesper Wengel Organic & biomolecular chemistry 2009 topics set
Human DNA polymerase eta is required for common fragile site stability during unperturbed DNA replication. Laurie Rey, Julia M Sidorova, Nadine Puget, François Boudsocq, Denis S F Biard, Raymond J Monnat, Christophe Cazaux, Jean-Sébastien Hoffmann Molecular and cellular biology 2009 pols set
Structural insight into processive human mitochondrial DNA synthesis and disease-related polymerase mutations. Young-Sam Lee, W Dexter Kennedy, Y Whitney Yin Cell 2009 partial results
Kinetic analysis of base-pairing preference for nucleotide incorporation opposite template pyrimidines by human DNA polymerase iota. Jeong-Yun Choi, Seonhee Lim, Robert Lawton Eoff, F Peter Guengerich Journal of molecular biology 2009 pols set
Role of DNA damage-induced replication checkpoint in promoting lesion bypass by translesion synthesis in yeast. Vincent Pagès, Sergio R Santa Maria, Louise Prakash, Satya Prakash Genes & development 2009 new
Mechanistic studies of the bypass of a bulky single-base lesion catalyzed by a Y-family DNA polymerase. Shanen M Sherrer, Jessica A Brown, Lindsey R Pack, Vijay P Jasti, Jason D Fowler, Ashis K Basu, Zucai Suo The Journal of biological chemistry 2009 topics set
The active form of DNA polymerase V is UmuD'(2)C-RecA-ATP. Qingfei Jiang, Kiyonobu Karata, Roger Woodgate, Michael M Cox, Myron F Goodman Nature 2009 pols set
Translesion DNA synthesis by human DNA polymerase eta on templates containing a pyrimidopurinone deoxyguanosine adduct, 3-(2'-deoxy-beta-d-erythro-pentofuranosyl)pyrimido-[1,2-a]purin-10(3H)-one . Jennifer B Stafford, Robert Lawton Eoff, Albena Kozekova, Carmelo J Rizzo, F Peter Guengerich, Lawrence J Marnett Biochemistry 2009 pols set
The family X DNA polymerase from Deinococcus radiodurans adopts a non-standard extended conformation. Nicolas Leulliot, Lionel Cladière, François Lecointe, Dominique Durand, Ulrich Hübscher, Herman van Tilbeurgh The Journal of biological chemistry 2009 topics set
Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases. Olga Rechkoblit, Lucy Malinina, Yuan Cheng, Nicholas E Geacintov, Suse Broyde, Dinshaw J Patel Structure (London, England : 1993) 2009 topics set
Alpha,beta-difluoromethylene deoxynucleoside 5'-triphosphates: a convenient synthesis of useful probes for DNA polymerase beta structure and function. Thomas G Upton, Boris A Kashemirov, Charles E McKenna, Myron F Goodman, G K Surya Prakash, Roman Kultyshev, Vinod K Batra, David D Shock, Lars C Pedersen, William A Beard, Samuel H Wilson Org Lett 2009 topics set
Construction of a circular single-stranded DNA template containing a defined lesion. Kiyonobu Karata, Antonio E Vidal, Roger Woodgate DNA repair 2009 pols set
Insights into the cellular role of enigmatic DNA polymerase iota. Antonio E Vidal, Roger Woodgate DNA repair 2009 pols set
Coupling DNA unwinding activity with primer synthesis in the bacteriophage T4 primosome. Maria Manosas, Michelle M Spiering, Zhihao Zhuang, Stephen J Benkovic, Vincent Croquette Nat Chem Biol 2009 topics set
Mitochondrial DNA depletion and fatal infantile hepatic failure due to mutations in the mitochondrial polymerase gamma (POLG) gene A combined morphological/enzyme histochemical and immunocytochemical/biochemical and molecular genetic study. J Müller-Höcker, R Horvath, S Schäfer, H Hessel, W Müller-Felber, J Kühr, William C Copeland, P Seibel Journal of cellular and molecular medicine 2009 new
Binding to PCNA in Euryarchaeal DNA Replication requires two PIP motifs for DNA polymerase D and one PIP motif for DNA polymerase B. Benoît Castrec, Christophe Rouillon, Ghislaine Henneke, Didier Flament, Joël Querellou, Jean-Paul Raffin Journal of molecular biology 2009 new
A computational study of the hydrolysis of dGTP analogues with halomethylene-modified leaving groups in solution: implications for the mechanism of DNA polymerases. Shina C L Kamerlin, Charles E McKenna, Myron F Goodman, Myron F Goondman, Arieh Warshel Biochemistry 2009 new
Translesion DNA polymerases remodel the replisome and alter the speed of the replicative helicase. Chiara Indiani, Lance D Langston, Olga Yurieva, Myron F Goodman, Mike E O'Donnell Proceedings of the National Academy of Sciences of the United States of America 2009 new
Clinical relevance of substitutions in the connection subdomain and RNase H domain of HIV-1 reverse transcriptase from a cohort of antiretroviral treatment-naïve patients. Atsuko Hachiya, Kazuki Shimane, Stefan G Sarafianos, Eiichi N Kodama, Yasuko Sakagami, Fujie Negishi, Hirokazu Koizumi, Hiroyuki Gatanaga, Masao Matsuoka, Masafumi Takiguchi, Shinichi Oka Antiviral research 2009 pols set
Nucleic acid polymerases use a general acid for nucleotidyl transfer. Christian Castro, Eric D Smidansky, Jamie J Arnold, Kenneth R Maksimchuk, Ibrahim Moustafa, Akira Uchida, Matthias Götte, William H Konigsberg, Craig E Cameron Nature structural & molecular biology 2009 new
Two cases of development of entecavir resistance during entecavir treatment for nucleoside-naive chronic hepatitis B. Haruhiko Kobashi, Shin-ichi Fujioka, Mitsuhiko Kawaguchi, Hiromitsu Kumada, Osamu Yokosuka, Norio Hayashi, Kazuyuki Suzuki, Takeshi Okanoue, Michio Sata, Hirohito Tsubouchi, Chifumi Sato, Kendo Kiyosawa, Kyuichi Tanikawa, Taku Seriu, Hiroki Ishikawa, Akinobu Takaki, Yoshiaki Iwasaki, Toshiya Osawa, Toshiyuki Takaki, Kosaku Sakaguchi, Yasushi Shiratori, Kazuhide Yamamoto, Daniel J Tenney, Masao Omata Hepatology international 2009 new
Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm. Takuji Oyama, Hayato Oka, Kouta Mayanagi, Tsuyoshi Shirai, Kyoko Matoba, Ryosuke Fujikane, Yoshizumi Ishino, Kosuke Morikawa BMC structural biology 2009 pols set
Effect of N-2-acetylaminofluorene and 2-aminofluorene adducts on DNA binding and synthesis by yeast DNA polymerase eta. Venkataramana Vooradi, Louis J Romano Biochemistry 2009 new
PCNA mono-ubiquitination and activation of translesion DNA polymerases by DNA polymerase {alpha}. Motoshi Suzuki, Atsuko Niimi, Siripan Limsirichaikul, Shuta Tomida, Qin Miao Huang, Shunji Izuta, Jiro Usukura, Yasutomo Itoh, Takashi Hishida, Tomohiro Akashi, Yoshiyuki Nakagawa, Akihiko Kikuchi, Youri I Pavlov, Takashi Murate, Tomonori Takahashi J Biochem 2009 new
Isolation of recombinant DNA elongation proteins. Barbara van Loon, Elena Ferrari, Ulrich Hübscher Methods in molecular biology (Clifton, N.J.) 2009 new
Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance. Lauren S Waters, Brenda K Minesinger, Mary Ellen Wiltrout, Sanjay D'Souza, Rachel V Woodruff, Graham C Walker Microbiol Mol Biol Rev 2009 topics set
Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis. Samir M Hamdan, Joseph J Loparo, Masateru Takahashi, Charles C Richardson, Antoine M van Oijen Nature 2009 new
Mutations in the gene 5 DNA polymerase of bacteriophage T7 suppress the dominant lethal phenotype of gene 2.5 ssDNA binding protein lacking the C-terminal phenylalanine. Boriana Marintcheva, Udi Qimron, Yao Yu, Stanley Tabor, Charles C Richardson, Charles C Richardson Molecular microbiology 2009 pols set
A passion for research. Margarita Salas Cellular and molecular life sciences : CMLS 2009 new
An in trans interaction at the interface of the helicase and primase domains of the hexameric gene 4 protein of bacteriophage T7 modulates their activities. B Zhu, Seung-Joo Lee, Charles C Richardson The Journal of biological chemistry 2009 new
SC29EK, a peptide fusion inhibitor with enhanced alpha-helicity, inhibits replication of human immunodeficiency virus type 1 mutants resistant to enfuvirtide. Takeshi Naito, Kazuki Izumi, Eiichi N Kodama, Yasuko Sakagami, Keiko Kajiwara, Hiroki Nishikawa, Kentaro Watanabe, Stefan G Sarafianos, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka Antimicrobial agents and chemotherapy 2009 pols set
[Study on the transmission of drug resistant human immunodeficiency virus-1 in Henan province]. Yuan Yuan, Xin-liang Cao, Hong-wei Liu, Hui Xing, Chun-hua Liu, Wei-guo Cui, Ding-yong Sun, Ning Li, Qian Zhu, Zhengqiang Wang, Yi-ming Shao Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 2009 new
Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals. Sigal Shachar, Omer Ziv, Sharon Avkin, Sheera Adar, John P Wittschieben, Thomas Reissner, Stephen Chaney, Errol C Friedberg, Zhengqiang Wang, Thomas Carell, Nicholas E Geacintov, Zvi Livneh The EMBO journal 2009 topics set
The resveratrol analogue 4,4'-dihydroxy-trans-stilbene inhibits cell proliferation with higher efficiency but different mechanism from resveratrol. Monica Savio, T Coppa, Livia Bianchi, Vanio Vannini, Giovanni Maga, L Forti, Ornella Cazzalini, M C Lazzè, Paola Perucca, Ennio Prosperi, Lucia A Stivala The international journal of biochemistry & cell biology 2009 new
Design of peptide-based inhibitors for human immunodeficiency virus type 1 strains resistant to T-20. Kazuki Izumi, Eiichi N Kodama, Kazuya Shimura, Yasuko Sakagami, Kentaro Watanabe, Saori Ito, Tsuyoshi Watabe, Yukihiro Terakawa, Hiroki Nishikawa, Stefan G Sarafianos, Kazuo Kitaura, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka The Journal of biological chemistry 2009 pols set
Characterization of DNA polymerase beta splicing variants in gastric cancer: the most frequent exon 2-deleted isoform is a non-coding RNA. Valeria Simonelli, Mariarosaria D'Errico, Domenico Palli, Rajendra Prasad, Samuel H Wilson, Eugenia Dogliotti Mutation research 2009 new
The use of 2-aminopurine fluorescence to study DNA polymerase function. Linda J Reha-Krantz Methods in molecular biology (Clifton, N.J.) 2009 complete
Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition. Stefan G Sarafianos, Bruno Marchand, Kalyan Das, Daniel M Himmel, Michael A. Parniak, Stephen H Hughes, Edward Arnold Journal of molecular biology 2009 pols set
Evolution of DNA polymerases: an inactivated polymerase-exonuclease module in Pol epsilon and a chimeric origin of eukaryotic polymerases from two classes of archaeal ancestors. Tahir H Tahirov, Kira S Makarova, Igor B Rogozin, Youri I Pavlov, Eugene V Koonin Biol Direct 2009 partial results
Myocardial bridging in aborted sudden death: just an innocent bystander? Paul Knaapen, Marco J W Götte, Carel C de Cock N Z Med J 2009 new
Replication across template T/U by human DNA polymerase-iota. Rinku Jain, Deepak T Nair, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Structure (London, England : 1993) 2009 topics set
R964C mutation of DNA polymerase gamma imparts increased stavudine toxicity by decreasing nucleoside analog discrimination and impairing polymerase activity. Christopher M Bailey, Rajesh Kasiviswanathan, William C Copeland, Karen S Anderson Antimicrob Agents Chemother 2009 topics set
Quinazolin-2-ylamino-quinazolin-4-ols as novel non-nucleoside inhibitors of bacterial DNA polymerase III. Joseph W Guiles, Xicheng Sun, Ian A Critchley, Urs Ochsner, Ming Tregay, Kim Stone, Jennifer Bertino, Louis S Green, Rob Sabin, Frank Dean, H Garry Dallmann, Charles S McHenry, Nebojsa Janjic Bioorganic & medicinal chemistry letters 2009 new
Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants. Dai-Shi Su, John J Lim, Elizabeth Tinney, Bang-Lin Wan, Mary Beth Young, Kenneth D Anderson, Deanne Rudd, Vandna Munshi, Carolyn Bahnck, Peter J Felock, Meiqing Lu, Ming-Tain Lai, Sinoeun Touch, Gregory Moyer, Daniel J Distefano, Jessica A Flynn, Yuexia Liang, Rosa Sanchez, Sridhar Prasad, Youwei Yan, Rebecca A Perlow-Poehnelt, Maricel Torrent, Michael D Miller, Joe P Vacca, Theresa M Williams, Neville J Anthony Bioorganic & medicinal chemistry letters 2009 partial results
A role for DNA polymerase mu in the emerging DJH rearrangements of the postgastrulation mouse embryo. Beatriz Gozalbo-López, Paula Andrade, Gloria Terrados, Belén de Andrés, Natalia Serrano, Isabel Cortegano, Beatriz Palacios, Antonio Bernad, Luis Blanco, Miguel A R Marcos, María Luisa Gaspar Molecular and cellular biology 2009 new
Indolylarylsulfones bearing natural and unnatural amino acids. Discovery of potent inhibitors of HIV-1 non-nucleoside wild type and resistant mutant strains reverse transcriptase and coxsackie B4 virus. Francesco Piscitelli, Antonio Coluccia, Andrea Brancale, Giuseppe La Regina, Anna Sansone, Cesare Giordano, Jan Balzarini, Giovanni Maga, Samantha Zanoli, Alberta Samuele, Roberto Cirilli, Francesco La Torre, Antonio Lavecchia, Ettore Novellino, Romano Silvestri Journal of medicinal chemistry 2009 pols set
A cluster of polypyrimidine tracts is involved in the transcription regulation of telomerase transcriptional elements-interacting factor. Ying Sun, Qian Sun, Michael A McNutt, Yilei Gong, Jiaochen Wang, Lin Hou, Qi Shen, Yun Ling, Yingkai Chi, Bo Zhang Molecular and cellular biochemistry 2009 new
GS-9191 is a novel topical prodrug of the nucleotide analog 9-(2-phosphonylmethoxyethyl)guanine with antiproliferative activity and possible utility in the treatment of human papillomavirus lesions. Grushenka H I Wolfgang, Riri Shibata, Jianying Wang, Adrian S Ray, Sylvia Wu, Edward Doerrfler, Hans Reiser, William A Lee, Gabriel Birkus, Neil D Christensen, Graciela Andrei, Robert Snoeck Antimicrobial agents and chemotherapy 2009 new
Proteolysis of the proofreading subunit controls the assembly of Escherichia coli DNA polymerase III catalytic core. Daniela Bressanin, Alessandra Stefan, Fabrizio Dal Piaz, Stefano Cianchetta, Luca Reggiani, Alejandro Hochkoeppler Biochimica et biophysica acta 2009 complete Alejandro Hochkoeppler*
Influence of local sequence context on damaged base conformation in human DNA polymerase iota: molecular dynamics studies of nucleotide incorporation opposite a benzo[a]pyrene-derived adenine lesion. Kerry Donny-Clark, Suse Broyde Nucleic acids research 2009 pols set
Bypass specialists operate together. Kei-ichi Takata, RichardD Wood The EMBO journal 2009 topics set
[Expression study of DNA translesion synthesis genes in human primary glioma]. Cai-hua Xi, Jin Hu, Hui-bo Wang, Shu-yu Zhang, Da-lu Ru Zhonghua yi xue za zhi 2009 topics set
Biochemical properties and base excision repair complex formation of apurinic/apyrimidinic endonuclease from Pyrococcus furiosus. Shinichi Kiyonari, Saki Tahara, Tsuyoshi Shirai, Shigenori Iwai, Sonoko Ishino, Yoshizumi Ishino Nucleic acids research 2009 new
A useful strategy to construct DNA polymerases with different properties by using genetic resources from environmental DNA. Hiroaki Matsukawa, Takeshi Yamagami, Yutaka Kawarabayasi, Yukiko Miyashita, Masaaki Takahashi, Yoshizumi Ishino Genes & genetic systems 2009 new
Replication past the N5-methyl-formamidopyrimidine lesion of deoxyguanosine by DNA polymerases and an improved procedure for sequence analysis of in vitro bypass products by mass spectrometry. Plamen P Christov, Karen C Angel, F Peter Guengerich, Carmelo J Rizzo Chemical research in toxicology 2009 pols set
MtDNA mutations are a common cause of severe disease phenotypes in children with Leigh syndrome. Karin Naess, Christoph Freyer, Helene Bruhn, Rolf Wibom, Gunilla Malm, Inger Nennesmo, Ulrika von Döbeln, Nils-Göran Larsson Biochimica et biophysica acta 2009 topics set
Substitution of Ile(707) for Leu in Klentaq DNA polymerase reduces the amplification capacity of the enzyme. K Davalieva, D G Efremov Prilozi 2009 new
Relationship between polymerase gamma (POLG) polymorphisms and antiretroviral therapy-induced lipodystrophy in HIV-1 infected patients: a case-control study. Franck Chiappini, Elina Teicher, Raphaël Saffroy, Brigitte Debuire, Daniel Vittecoq, Antoinette Lemoine Current HIV research 2009 pols set
A variable neurodegenerative phenotype with polymerase gamma mutation. S Stricker, H Prüss, R Horvath, Enrico Baruffini, Tiziana Lodi, E Siebert, M Endres, R Zschenderlein, A Meisel Journal of neurology, neurosurgery, and psychiatry 2009 pols set
Two novel POLG mutations causing hepatic mitochondrial DNA depletion with recurrent hypoketotic hypoglycaemia and fatal liver dysfunction. B Bortot, E Barbi, S Biffi, G Lunazzi, R Bussani, A Burlina, S Norbedo, A Ventura, M Carrozzi, G M Severini Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2009 pols set
Mutations in mitochondrial DNA polymerase-gamma promote breast tumorigenesis. Keshav K Singh, Vanniarajan Ayyasamy, Kjerstin M Owens, Manika Sapru Koul, Marija Vujcic Journal of human genetics 2009 pols set
Digenic mutations in severe myoclonic epilepsy of infancy. Maija Bolszak, Anna-Kaisa Anttonen, Tuomas Komulainen, Reetta Hinttala, Salla Pakanen, Raija Sormunen, Riitta Herva, Anna-Elina Lehesjoki, Kari Majamaa, Heikki Rantala, Johanna Uusimaa Epilepsy research 2009 complete Johanna Uusimaa*
Structure-function relationships in miscoding by Sulfolobus solfataricus DNA polymerase Dpo4: guanine N2,N2-dimethyl substitution produces inactive and miscoding polymerase complexes. Haijiang Zhang, Robert Lawton Eoff, Ivan D Kozekov, Carmelo J Rizzo, Martin Egli, F Peter Guengerich The Journal of biological chemistry 2009 topics set
Structure of human DNA polymerase kappa inserting dATP opposite an 8-OxoG DNA lesion. Rodrigo Vasquez-Del Carpio, Timothy D Silverstein, Samer Lone, Michael K Swan, Jayati Roy Choudhury, Robert E Johnson, Satya Prakash, Louise Prakash, Aneel K Aggarwal PloS one 2009 topics set
Effect of testosterone on E1S-sulfatase activity in non-malignant and cancerous breast cells in vitro. Matthias Götte, Kathrin Kalkhake, Sebastian Ploeger, Ludwig Kiesel, Petra Stute J Steroid Biochem Mol Biol 2009 new
Structural determinant for switching between the polymerase and exonuclease modes in the PCNA-replicative DNA polymerase complex. Hirokazu Nishida, Kouta Mayanagi, Shinichi Kiyonari, Yuichi Sato, Takuji Oyama, Yoshizumi Ishino, Kosuke Morikawa Proceedings of the National Academy of Sciences of the United States of America 2009 new
Structural insight into translesion synthesis by DNA Pol II. Feng Wang, Wei Wen Yang Cell 2009 topics set
Mitochondrial DNA depletion in progressive external ophthalmoplegia caused by POLG1 mutations. Charalampos Tzoulis, M Papingji, T Fiskestrand, L S Røste, Laurence A Bindoff Acta neurologica Scandinavica. Supplementum 2009 pols set
Clinical reasoning: Blurred vision and dancing feet: restless legs syndrome presenting in mitochondrial disease. H Aitken, G Gorman, Robert McFarland, M Roberts, Robert W Taylor, Douglass M Turnbull Neurology 2009 pols set
Clinical and molecular features of mitochondrial DNA depletion syndromes. A Spinazzola, Federica Invernizzi, Franco Carrara, Eleonora Lamantea, Alice Donati, M Dirocco, I Giordano, M Meznaric-Petrusa, Enrico Baruffini, Iliana Ferrero, Massimo Zeviani Journal of inherited metabolic disease 2009 pols set
A slow ATP-induced conformational change limits the rate of DNA binding but not the rate of beta clamp binding by the escherichia coli gamma complex clamp loader. Jennifer A Thompson, Christopher O Paschall, Mike E O'Donnell, Linda B Bloom The Journal of biological chemistry 2009 complete Linda B Bloom*
[Construction and application of a genechip method for detection of hepatitis B virus lamivudine-resistant mutants and basal core promotor/Pre-C mutants]. Bing Li, Bo-Ping Zhou, Jin-Fu Peng, Li-Yan Chen, Weiming Zhang, Wei Tang, Zhao-Qin Wang, Zhong-Hua Yin, Liu-Mei Xu, Rui-Ling Luo, Xiao-He Li, Sai-Yun Liu Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 2009 new
Analysis of mutant DNA polymerase gamma in patients with mitochondrial DNA depletion. Jan-Willem Taanman, Shamima Rahman, Alistair T Pagnamenta, Andrew A M Morris, Maria Bitner-Glindzicz, Nicole I Wolf, James V Leonard, Peter T Clayton, Anthony H V Schapira Hum Mutat 2009 pols set
Interaction with DNA polymerase eta is required for nuclear accumulation of REV1 and suppression of spontaneous mutations in human cells. Jun-Ichi Akagi, Chikahide Masutani, Yuki Kataoka, Takashi Kan, Eiji Ohashi, Toshio Mori, Haruo Ohmori, Fumio Hanaoka DNA repair 2009 new
HIV-1 reverse transcriptase can simultaneously engage its DNA/RNA substrate at both DNA polymerase and RNase H active sites: implications for RNase H inhibition. Greg L Beilhartz, Michaela Wendeler, Noel S Baichoo, Jason W Rausch, Stuart F J Le Grice, Matthias Götte Journal of molecular biology 2009 complete Bruno Marchand
Role of the heparan sulfate proteoglycan syndecan-1 (CD138) in delayed-type hypersensitivity. Behzad Kharabi Masouleh, Gerdy B Ten Dam, Martin K Wild, Ruth Seelige, Johan van der Vlag, Angelique L Rops, Frank G Echtermeyer, Dietmar Vestweber, Toin H van Kuppevelt, Ludwig Kiesel, Matthias Götte J Immunol 2009 new
The essential role of p53 in hyperpigmentation of the skin via regulation of paracrine melanogenic cytokine receptor signaling. Daiki Murase, Akira Hachiya, Yasuko Amano, Atsushi Ohuchi, Takashi Kitahara, Yoshinori Takema The Journal of biological chemistry 2009 new
Phenotypic variations in 3 children with POLG1 mutations. Prinyarat Burusnukul, Emily C de los Reyes Journal of child neurology 2009 pols set
Loop II of DNA polymerase beta is important for discrimination during substrate binding. George C Lin, Joachim Jaeger, Kristin A Eckert, Joann B Sweasy DNA repair 2009 new
Disease mutations in the human mitochondrial DNA polymerase thumb subdomain impart severe defects in mitochondrial DNA replication. Rajesh Kasiviswanathan, Matthew J Longley, Sherine S L Chan, William C Copeland The Journal of biological chemistry 2009 new
Inhibition of human DNA polymerase beta activity by the anticancer prodrug Cloretazine. Abbie M Frederick, Marguerite L Davis, Kevin P Rice Biochem Biophys Res Commun 2009 pols set
DNA polymerase mu interacts with a meiosis-specific RecA homolog Lim15 during meiosis in Coprinus cinereus. Takuro Yanai, Aiko Sakamoto, Kazuki Iwabata, Akiyo Koshiyama, Hiroko Sugawara, Takayuki Nara, Yoichi Takakusagi, Kengo Sakaguchi Biochem Biophys Res Commun 2009 new
The polymerase eta translesion synthesis DNA polymerase acts independently of the mismatch repair system to limit mutagenesis caused by 7,8-dihydro-8-oxoguanine in yeast. Sarah V Mudrak, Caroline Welz-Voegele, Sue Jinks-Robertson Molecular and cellular biology 2009 new
Synthesis and DNA polymerase alpha and beta inhibitory activity of alkyl p-coumarates and related compounds. Katsumi Nishimura, Yukiko Takenaka, Manami Kishi, Takao Tanahashi, Hiromi Yoshida, Chiaki Okuda, Yoshiyuki Mizushina Chem Pharm Bull (Tokyo) 2009 new
The steric gate amino acid tyrosine 112 is required for efficient mismatched-primer extension by human DNA polymerase kappa. Naoko Niimi, Akira Sassa, Atsushi Katafuchi, Petr Grúz, Hirofumi Fujimoto, Radha-Rani Bonala, Francis Johnson, Toshihiro Ohta, Takehiko Nohmi Biochemistry 2009 pols set
Fatal congenital myopathy and gastrointestinal pseudo-obstruction due to POLG1 mutations. C Giordano, H Powell, M Leopizzi, M De Curtis, M de Curtis, C Travaglini, M Sebastiani, P Gallo, Robert W Taylor, G d'Amati Neurology 2009 pols set
Physical interactions between Mcm10, DNA, and DNA polymerase alpha. Eric M Warren, Hao Huang, Ellen Fanning, Walter J Chazin, Brandt F Eichman The Journal of biological chemistry 2009 complete Brandt F Eichman*
Functional importance of bacteriophage phi29 DNA polymerase residue Tyr148 in primer-terminus stabilisation at the 3'-5' exonuclease active site. Patricia Pérez-Arnaiz, José María Lázaro, Margarita Salas, Miguel de Vega Journal of molecular biology 2009 partial results
Selective recognition of unnatural imidazopyridopyrimidine:naphthyridine base pairs consisting of four hydrogen bonds by the Klenow fragment. Noriaki Minakawa, Shintaro Ogata, Mayumi Takahashi, Akira Matsuda Journal of the American Chemical Society 2009 topics set
Role of TLS DNA polymerases eta and kappa in processing naturally occurring structured DNA in human cells. Rémy Bétous, Laurie Rey, Guliang Wang, Marie-Jeanne Pillaire, Nadine Puget, Janick Selves, Denis S F Biard, Kazuo Shin-ya, Karen M Vasquez, Christophe Cazaux, Jean-Sébastien Hoffmann Molecular carcinogenesis 2009 pols set
Base excision repair in early zebrafish development: evidence for DNA polymerase switching and standby AP endonuclease activity. Sean Fortier, Xiaojie Yang, Yazhen Wang, Richard A O Bennett, Phyllis R Strauss Biochemistry 2009 topics set
Pif1 helicase lengthens some Okazaki fragment flaps necessitating Dna2 nuclease/helicase action in the two-nuclease processing pathway. JasonE Pike, PeterMJ Burgers, JudithL Campbell, RobertA Bambara The Journal of biological chemistry 2009 new
Structural insights into yeast DNA polymerase delta by small angle X-ray scattering. Rinku Jain, Michal Hammel, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Journal of molecular biology 2009 new
DNA synthesis across an abasic lesion by human DNA polymerase iota. Deepak T Nair, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Structure (London, England : 1993) 2009 topics set
Mutations in the thumb allow human immunodeficiency virus type 1 reverse transcriptase to be cleaved by protease in virions. Linda L Dunn, Mary Jane McWilliams, Kalyan Das, Edward Arnold, Stephen H Hughes Journal of virology 2009 pols set
Conformational landscape of the human immunodeficiency virus type 1 reverse transcriptase non-nucleoside inhibitor binding pocket: lessons for inhibitor design from a cluster analysis of many crystal structures. Kristina A Paris, Omar Haq, Anthony K Felts, Kalyan Das, Edward Arnold, Ronald M Levy Journal of medicinal chemistry 2009 pols set
Characterization of intein homing endonuclease encoded in the DNA polymerase gene of Thermococcus marinus. Heejin Bae, Kee Pum Kim, Jung Min Song, Jun-Hwan Kim, Joo-Sung Yang, Suk-Tae Kwon FEMS Microbiol Lett 2009 new
Aberrant DNA polymerase alpha is excluded from the nucleus by defective import and degradation in the nucleus. Christian S Eichinger, Takeshi Mizuno, Keiko Mizuno, Yasuyuki Miyake, Ken-ichiro Yanagi, Naoko Imamoto, Fumio Hanaoka The Journal of biological chemistry 2009 complete Takeshi Mizuno*
Evidence for the involvement of human DNA polymerase N in the repair of DNA interstrand cross-links. Laura Zietlow, Leigh Anne Smith, Mika Bessho, Tadayoshi Bessho Biochemistry 2009 complete Tadayoshi Bessho*
Defective interaction between Pol2p and Dpb2p, subunits of DNA polymerase epsilon, contributes to a mutator phenotype in Saccharomyces cerevisiae. Malgorzata Jaszczur, Justyna Rudzka, Joanna Kraszewska, Krzysztof Flis, Piotr Polaczek, Judith L Campbell, I Fijalkowska, Piotr Jonczyk Mutation research 2009 pols set
Specific nucleotide binding and rebinding to individual DNA polymerase complexes captured on a nanopore. Nicholas Hurt, Hongyun Wang, Mark Akeson, Kate R Lieberman Journal of the American Chemical Society 2009 complete Kate R Lieberman*
A novel interaction between human DNA polymerase eta and MutLalpha. Rie Kanao, Fumio Hanaoka, Chikahide Masutani Biochem Biophys Res Commun 2009 pols set
Reaction mechanism of the epsilon subunit of E. coli DNA polymerase III: insights into active site metal coordination and catalytically significant residues. G Andrés Cisneros, Lalith Perera, Roel M Schaaper, Lars C Pedersen, Robert E London, Lee G Pedersen, Thomas A Darden Journal of the American Chemical Society 2009 pols set
Role of the 2-amino group of purines during dNTP polymerization by human DNA polymerase alpha. Jennifer N Patro, Milan Urban, Robert D Kuchta Biochemistry 2009 pols set
Characterization of the 5' to 3' nuclease activity of Thermus aquaticus DNA polymerase on fluorogenic double-stranded probes. Qiuying Huang, Qingge Li Mol Cell Probes 2009 complete Qingge Li*
DNA polymerase gamma and mitochondrial disease: understanding the consequence of POLG mutations. Sherine S L Chan, William C Copeland Biochimica et biophysica acta 2009 new
Efficiency and specificity of microRNA-primed nucleotide analog incorporation by various DNA polymerases. Younguk Sun, Kalvin J Gregory, Val Golovlev Anal Biochem 2009 topics set
Distinct beta-clamp interactions govern the activities of the Y family PolIV DNA polymerase. Jérôme E Wagner, Hélène Etienne, Robert P P Fuchs, Agnes M Cordonnier, Dominique Y Burnouf Molecular microbiology 2009 complete Jérôme E Wagner*
DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice. Tina M Albertson, Masanori Ogawa, James M Bugni, Laura E Hays, Yang Chen, Yanping Wang, Piper M Treuting, John A Heddle, Robert E Goldsby, Bradley D Preston Proceedings of the National Academy of Sciences of the United States of America 2009 topics set
Cloning and characterization of DNA polymerase eta from Trypanosoma cruzi: roles for translesion bypass of oxidative damage. Michelle Barbi de Moura, Bruno Luiz Fonseca Schamber-Reis, Danielle Gomes Passos Silva, Matheus Andrade Rajão, Andréa Mara Macedo, Glória Regina Franco, Sérgio Danilo Junho Pena, Santuza Maria Ribeiro Teixeira, Carlos Renato Machado Environ Mol Mutagen 2009 complete Carlos Renato Machado*
The reopening rate of the fingers domain is a determinant of base selectivity for RB69 DNA polymerase. Harold R Lee, Michael Wang, William H Konigsberg Biochemistry 2009 complete
Unnatural imidazopyridopyrimidine:naphthyridine base pairs: selective incorporation and extension reaction by Deep Vent (exo- ) DNA polymerase. Shintaro Ogata, Mayumi Takahashi, Noriaki Minakawa, Akira Matsuda Nucleic acids research 2009 partial results
DNA polymerase delta is required for early mammalian embryogenesis. Arikuni Uchimura, Yuko Hidaka, Takahiro Hirabayashi, Masumi Hirabayashi, Takeshi Yagi PloS one 2009 complete Arikuni Uchimura*
HIV inactivation by cross-linking of photo-labeled anti-retroviral compounds with HIV reverse transcriptase. Susan P Colby-Germinario, Adan Rios, Jorge Quesada, Dallas Anderson, Allan L Goldstein, Theresa Fossum, Mark A. Wainberg Vaccine 2009 pols set
Characterization of DNA polymerase X from Thermus thermophilus HB8 reveals the POLXc and PHP domains are both required for 3'-5' exonuclease activity. Shuhei Nakane, Noriko Nakagawa, Seiki Kuramitsu, Ryoji Masui Nucleic acids research 2009 topics set
A model for DNA polymerase switching involving a single cleft and the rim of the sliding clamp. Justin M H Heltzel, Robert W Maul, Sarah K Scouten Ponticelli, Mark D Sutton Proceedings of the National Academy of Sciences of the United States of America 2009 topics set
The 3'-to-5' exonuclease activity of vaccinia virus DNA polymerase is essential and plays a role in promoting virus genetic recombination. Don B Gammon, David H Evans J Virol 2009 complete David H Evans*
Replication stress leads to genome instabilities in Arabidopsis DNA polymerase delta mutants. David Schuermann, Olivier Fritsch, Jan M Lucht, Barbara Hohn Plant Cell 2009 complete David Schuermann*
Different behaviors in vivo of mutations in the beta hairpin loop of the DNA polymerases of the closely related phages T4 and RB69. Anna Trzemecka, Danuta Płochocka, Anna Bebenek Journal of molecular biology 2009 partial results
Electronic control of DNA polymerase binding and unbinding to single DNA molecules. Noah A Wilson, Robin Abu-Shumays, Brett Gyarfas, Hongyun Wang, Kate R Lieberman, Mark Akeson, William B Dunbar ACS nano 2009 complete Kate R Lieberman*
Site-specific labeling of T7 DNA polymerase with a conformationally sensitive fluorophore and its use in detecting single-nucleotide polymorphisms. Yu-Chih Tsai, Zhinan Jin, Kenneth A Johnson Analytical biochemistry 2009 pols set
Telbivudine, a nucleoside analog inhibitor of HBV polymerase, has a different in vitro cross-resistance profile than the nucleotide analog inhibitors adefovir and tenofovir. Maria Seifer, April Patty, Ilaria Serra, Bin Li, David N Standring Antiviral Res 2009 topics set
Sliding clamp-DNA interactions are required for viability and contribute to DNA polymerase management in Escherichia coli. Justin M H Heltzel, Sarah K Scouten Ponticelli, Laurie H Sanders, Jill M Duzen, Vivian Cody, James Pace, Edward H Snell, Mark D Sutton Journal of molecular biology 2009 topics set
Mapping the position of DNA polymerase-bound DNA templates in a nanopore at 5 A resolution. Brett Gyarfas, Felix Olasagasti, Seico Benner, Daniel R Garalde, Kate R Lieberman, Mark Akeson ACS nano 2009 complete Kate R Lieberman*
DNA damage alters DNA polymerase delta to a form that exhibits increased discrimination against modified template bases and mismatched primers. Xiao Meng, Yanjiao Zhou, Sufang Zhang, Ernest Y C Lee, David N Frick, Marietta Y W T Lee Nucleic acids research 2009 topics set
Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents. Anna-Maria Monforte, Patrizia Logoteta, Stefania Ferro, Laura De Luca, Nunzio Iraci, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri Bioorganic & medicinal chemistry 2009 pols set
Lack of DNA polymerase theta (POLQ) radiosensitizes bone marrow stromal cells in vitro and increases reticulocyte micronuclei after total-body irradiation. Julie P Goff, Donna S Shields, Masayuki Seki, Serah Choi, Michael W Epperly, Tracy Dixon, Hong Wang, Christopher J Bakkenist, Stephen D Dertinger, Dorothea K Torous, John P Wittschieben, Richard D Wood, Joel S Greenberger Radiat Res 2009 new
Transplantation of BMSCs expressing hPDGF-A/hBD2 promotes wound healing in rats with combined radiation-wound injury. L Hao, Jiqun Wang, Z Zou, G Yan, S Dong, J Deng, X Ran, Y Feng, Chen Luo, Yujue Wang, T Cheng Gene therapy 2009 new
DNA polymerase kappa from Trypanosoma cruzi localizes to the mitochondria, bypasses 8-oxoguanine lesions and performs DNA synthesis in a recombination intermediate. Matheus Andrade Rajão, D G Passos-Silva, Wanderson Duarte DaRocha, Glória Regina Franco, Andréa Mara Macedo, Sérgio Danilo Junho Pena, Santuza Maria Ribeiro Teixeira, Carlos Renato Machado Molecular microbiology 2009 complete Carlos Renato Machado*
Distribution and roles of X-family DNA polymerases in eukaryotes. Yukinobu Uchiyama, Ryo Takeuchi, Hirofumi Kodera, Kengo Sakaguchi Biochimie 2009 new
PCNA is required for initiation of recombination-associated DNA synthesis by DNA polymerase delta. Xincang Li, Carrie M W Stith, Peter M J Burgers, Wolf-Dietrich Heyer Molecular cell 2009 new
Template strand scrunching during DNA gap repair synthesis by human polymerase lambda. Miguel Garcia-Diaz, Katarzyna Bebenek, Andres A Larrea, Jody M Havener, Lalith Perera, Joseph M Krahn, Lars C Pedersen, Dale A Ramsden, Thomas A Kunkel Nature structural & molecular biology 2009 new
Mitochondrial mosaics in the liver of 3 infants with mtDNA defects. Frank Roels, Patrick Verloo, François Eyskens, Baudouin François, Sara Seneca, Boel De Paepe, Jean-Jacques Martin, Valerie Meersschaut, Marleen Praet, Emmanuel Scalais, Marc Espeel, Joél Smet, Gert Van Goethem, Rudy Van Coster BMC clinical pathology 2009 pols set
Ataxia with ophthalmoplegia or sensory neuropathy is frequently caused by POLG mutations. Claudia Schulte, Matthis Synofzik, Thomas Gasser, Ludger Schöls Neurology 2009 pols set
Altered hematopoiesis in mice lacking DNA polymerase mu is due to inefficient double-strand break repair. Daniel Lucas, Beatriz Escudero, José Manuel Ligos, Jose Carlos Segovia, Juan Camilo Estrada, Gloria Terrados, Luis Blanco, Enrique Samper, Antonio Bernad PLoS Genet 2009 new
The nucleoside analogue D-carba T blocks HIV-1 reverse transcription. Paul L Boyer, B Christie Vu, Zandrea Ambrose, John G Julias, Svenja Warnecke, Chenzhong Liao, Chris Meier, Victor E Marquez, Stephen H Hughes Journal of medicinal chemistry 2009 pols set
Inhibition of translesion DNA polymerase by archaeal reverse gyrase. Anna Valenti, Giuseppe Perugino, Takehiko Nohmi, Mosè Rossi, Maria Ciaramella Nucleic acids research 2009 complete Maria Ciaramella*
Novel POLG1 mutations associated with neuromuscular and liver phenotypes in adults and children. Joanna D Stewart, S Tennant, H Powell, A Pyle, E L Blakely, L He, Gavin Hudson, M Roberts, D du Plessis, D Gow, L D Mewasingh, M G Hanna, S Omer, A A Morris, R Roxburgh, J H Livingston, Robert McFarland, Douglass M Turnbull, Patrick F Chinnery, Robert W Taylor Journal of medical genetics 2009 pols set
Ambivalent incorporation of the fluorescent cytosine analogues tC and tCo by human DNA polymerase alpha and Klenow fragment. Gudrun Stengel, Byron W Purse, L Marcus Wilhelmsson, Milan Urban, Robert D Kuchta Biochemistry 2009 topics set
Rescue of bacteriophage T7 DNA polymerase of low processivity by suppressor mutations affecting gene 3 endonuclease. Seung-Joo Lee, Kajal Chowdhury, Stanley Tabor, Charles C Richardson Journal of virology 2009 topics set
Elucidating the kinetic mechanism of DNA polymerization catalyzed by Sulfolobus solfataricus P2 DNA polymerase B1. Jessica A Brown, Zucai Suo Biochemistry 2009 new
High-cell density shake-flask expression and rapid purification of the large fragment of Thermus aquaticus DNA polymerase I using a new chemically and temperature inducible expression plasmid in Escherichia coli. J W Brandis, Kenneth A Johnson Protein expression and purification 2009 topics set
Crystal structure of a trypanocidal 4,4'-bis(imidazolinylamino)diphenylamine bound to DNA. LaTeca S Glass, Binh Nguyen, Kristie D Goodwin, Christophe Dardonville, W David Wilson, Eric C Long, Millie M Georgiadis Biochemistry 2009 topics set
Crystal structure analysis of DNA lesion repair and tolerance mechanisms. Sabine Schneider, Stephanie Schorr, Thomas Carell Current opinion in structural biology 2009 topics set
Multidrug-resistant variants of HIV type 1 (HIV-1) can exist in cells as defective quasispecies and be rescued by superinfection with other defective HIV-1 variants. Yudong Quan, Chen Liang, Bluma G Brenner, Mark A. Wainberg The Journal of infectious diseases 2009 pols set
The block of DNA polymerase delta strand displacement activity by an abasic site can be rescued by the concerted action of DNA polymerase beta and Flap endonuclease 1. Giovanni Maga, Barbara van Loon, Emmanuele Crespan, Giuseppe Villani, Ulrich Hübscher The Journal of biological chemistry 2009 new
Single-molecule measurements of synthesis by DNA polymerase with base-pair resolution. Thomas David Christian, Louis J Romano, David Rueda Proceedings of the National Academy of Sciences of the United States of America 2009 new
Replication stress activates DNA polymerase alpha-associated Chk1. Lorena Taricani, Frances Shanahan, David Parry Cell Cycle 2009 new
A possible mechanism for the dynamics of transition between polymerase and exonuclease sites in a high-fidelity DNA polymerase. Ping Xie J Theor Biol 2009 complete Ping Xie*
Functional analysis of mutant mitochondrial DNA polymerase proteins involved in human disease. Sherine S L Chan, William C Copeland Methods in molecular biology (Clifton, N.J.) 2009 new
Transcription and reverse transcription of artificial nucleic acids involving backbone modification by template-directed DNA polymerase reactions. Masayasu Kuwahara, Hidetoshi Takeshima, Jun-ichi Nagashima, Satoshi Minezaki, Hiroaki Ozaki, Hiroaki Sawai Bioorg Med Chem 2009 new
Kinetics of deoxy-CTP incorporation opposite a dG-C8-N-2-aminofluorene adduct by a high-fidelity DNA polymerase. Dominique Y Burnouf, Jérôme E Wagner Journal of molecular biology 2009 new
Accommodation of an N-(deoxyguanosin-8-yl)-2-acetylaminofluorene adduct in the active site of human DNA polymerase iota: Hoogsteen or Watson-Crick base pairing? Kerry Donny-Clark, Robert Shapiro, Suse Broyde Biochemistry 2009 pols set
The inhibitory action of kohamaic acid A derivatives on mammalian DNA polymerase beta. Yoshiyuki Mizushina, Daisuke Manita, Toshifumi Takeuchi, Fumio Sugawara, Yuko Kumamoto-Yonezawa, Yuki Matsui, Masaharu Takemura, Mitsuru Sasaki, Hiromi Yoshida, Hirosato Takikawa Molecules 2009 pols set
Initiation of new DNA strands by the herpes simplex virus-1 primase-helicase complex and either herpes DNA polymerase or human DNA polymerase alpha. Nisha A Cavanaugh, Robert D Kuchta The Journal of biological chemistry 2009 new
Reducing the impact of PCR-mediated recombination in molecular evolution and environmental studies using a new-generation high-fidelity DNA polymerase. Daniel J G Lahr, Laura A Katz BioTechniques 2009 new
The mechanistic architecture of thermostable Pyrococcus furiosus family B DNA polymerase motif A and its interaction with the dNTP substrate. Edward M Kennedy, Christopher Hergott, Stephen Dewhurst, Baek Kim Biochemistry 2009 new
Modulation of the structure, catalytic activity, and fidelity of African swine fever virus DNA polymerase X by a reversible disulfide switch. Markus W Voehler, Robert Lawton Eoff, W Hayes McDonald, F Peter Guengerich, Michael P Stone The Journal of biological chemistry 2009 new
DNA polymerase zeta is essential for hexavalent chromium-induced mutagenesis. Travis J O'Brien, Preston Witcher, Bradford Brooks, Steven R Patierno Mutation research 2009 new
Analysis of the association of the human cytomegalovirus DNA polymerase subunit UL44 with the viral DNA replication factor UL84. Blair L Strang, Elisa Sinigalia, Laurie A Silva, Donald M Coen, Arianna Loregian J Virol 2009 pols set
Specific inhibitors of mammalian DNA polymerase species. Yoshiyuki Mizushina Biosci Biotechnol Biochem 2009 pols set
High fidelity and lesion bypass capability of human DNA polymerase delta. Michael W Schmitt, Yoshihiro Matsumoto, Lawrence A Loeb Biochimie 2009 pols set
DNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients. Omer Ziv, Nicholas E Geacintov, Satoshi Nakajima, Akira Yasui, Zvi Livneh Proceedings of the National Academy of Sciences of the United States of America 2009 new
TopBP1 and DNA polymerase alpha-mediated recruitment of the 9-1-1 complex to stalled replication forks: implications for a replication restart-based mechanism for ATR checkpoint activation. Shan Yan, W Matthew Michael Cell Cycle 2009 new
DNA polymerase beta and PARP activities in base excision repair in living cells. Aya Masaoka, Julie K Horton, William A Beard, Samuel H Wilson DNA repair 2009 new
A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome. Agnieszka Gambus, Frederick van Deursen, Dimitrios Polychronopoulos, Magdalena Foltman, Richard C Jones, Ricky D Edmondson, Arturo Calzada, Karim Labib The EMBO journal 2009 new
DNA polymerase X from Deinococcus radiodurans implicated in bacterial tolerance to DNA damage is characterized as a short patch base excision repair polymerase. Nivedita P Khairnar, Hari S Misra Microbiology 2009 pols set
Highly error-free role of DNA polymerase eta in the replicative bypass of UV-induced pyrimidine dimers in mouse and human cells. Jung-Hoon Yoon, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2009 new
Crystallographic study of a novel subnanomolar inhibitor provides insight on the binding interactions of alkenyldiarylmethanes with human immunodeficiency virus-1 reverse transcriptase. Matthew D Cullen, William C Ho, Joseph David Bauman, Kalyan Das, Edward Arnold, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman J Med Chem 2009 partial results
The mechanism of ATP-dependent primer-template recognition by a clamp loader complex. Kyle R Simonetta, Steven L Kazmirski, Eric R Goedken, Aaron J Cantor, Brian A Kelch, Randall McNally, Steven N Seyedin, Debora L Makino, Mike E O'Donnell, John Kuriyan Cell 2009 topics set
Crystal structure of epstein-barr virus DNA polymerase processivity factor BMRF1. Kazutaka Murayama, Sanae Nakayama, Miyuki Kato-Murayama, Ryogo Akasaka, Naomi Ohbayashi, Yuki Kamewari-Hayami, Takaho Terada, Mikako Shirouzu, Tatsuya Tsurumi, Shigeyuki Yokoyama The Journal of biological chemistry 2009 new
A novel inhibitor of DNA polymerase beta enhances the ability of temozolomide to impair the growth of colon cancer cells. Aruna S Jaiswal, Sanjeev Banerjee, Harekrushna Panda, Charles D Bulkin, Tadahide Izumi, Fazlul H Sarkar, David A Ostrov, Satya Narayan Mol Cancer Res 2009 new
Identification of a novel REV1-interacting motif necessary for DNA polymerase kappa function. Eiji Ohashi, Tomo Hanafusa, Keijiro Kamei, Ihnyoung Song, Junya Tomida, Hiroshi Hashimoto, Cyrus Vaziri, Haruo Ohmori Genes Cells 2009 pols set
Restoring 3'-5' exonuclease activity of thermophilic Geobacillus DNA polymerase I using site-directed mutagenesis in active site. Nasrin Rastgoo, Majid Sadeghizadeh, Bijan Bambaei, Saman Hosseinkhani J Biotechnol 2009 new
Visualizing sequence-governed nucleotide selectivities and mutagenic consequences through a replicative cycle: processing of a bulky carcinogen N2-dG lesion in a Y-family DNA polymerase. Pingna Xu, Lida Oum, Yuan-Cho Lee, Nicholas E Geacintov, Suse Broyde Biochemistry 2009 new
Preparation of long sticky ends for universal ligation-independent cloning: sequential T4 DNA polymerase treatments. Akira Tachibana, Kazuo Tohiguchi, Takayuki Ueno, Yuichi Setogawa, Ayako Harada, Toshizumi Tanabe J Biosci Bioeng 2009 pols set
Characterization and PCR optimization of the thermostable family B DNA polymerase from Thermococcus guaymasensis Suk-Tae Kwon, Hyekyung Shim, Jin Choia Jeong, Jae Kima Yun, Jae-Geun Songa, Eui-Joon Kila, Il Lee Jong Enzyme and microbial technology 2009 partial results
The balance between the rates of incorporation and pyrophosphorolytic removal influences the HIV-1 reverse transcriptase bypass of an abasic site with deoxy-, dideoxy-, and ribonucleotides. Bechan Sharma, Emmanuele Crespan, Giuseppe Villani, Giovanni Maga Proteins 2008 pols set
The four-and-a-half-LIM protein 2 (FHL2) is overexpressed in gliomas and associated with oncogenic activities. Ming Li, Jide Wang, Samuel S M Ng, Chu-Yan Chan, Amy C Chen, Hong Ping Xia, David T Yew, Benjamin Chun-Yu Wong, Zhu Chen, Hsiang-Fu Kung, Marie Chia-Mi Lin Glia 2008 new
Rapid detection and identification of a pathogen's DNA using Phi29 DNA polymerase. Yun Xu, Simon Gao, John F Bruno, Benjamin J Luft, John J Dunn Biochem Biophys Res Commun 2008 pols set
[Preliminary study of DNA polymerase beta gene silencing by small interfering RNA in human gastric cancer BGC-823 cells]. Guo-qiang Zhao, Lei Wang, Zi-ming Dong Zhonghua Zhong Liu Za Zhi 2008 new
Persistent presence of postoperative circulating tumor cells is a poor prognostic factor for patients with stage I-III colorectal cancer after curative resection. Yih-Huei Uen, Chien-Yu Lu, Hsiang-Lin Tsai, Fang-Jung Yu, Ming-Yii Huang, Tian-Lu Cheng, Shiu-Ru Lin, Jaw-Yuan Wang Annals of surgical oncology 2008 new
Reversible valproate hepatotoxicity due to mutations in mitochondrial DNA polymerase gamma (POLG1). Robert McFarland, Gavin Hudson, Robert W Taylor, S H Green, S Hodges, P J McKiernan, Patrick F Chinnery, V Ramesh Archives of disease in childhood 2008 pols set
Control of DNA polymerase lambda stability by phosphorylation and ubiquitination during the cell cycle. Ursula Wimmer, Elena Ferrari, Peter Hunziker, Ulrich Hübscher EMBO Rep 2008 new
Gene 1.7 of bacteriophage T7 confers sensitivity of phage growth to dideoxythymidine. Ngoc Quang Tran, Lisa F Rezende, Udi Qimron, Charles C Richardson, Stanley Tabor Proceedings of the National Academy of Sciences of the United States of America 2008 pols set
Establishment of immortalized human hepatocytes by introduction of HPV16 E6/E7 and hTERT as cell sources for liver cell-based therapy. Yosuke Tsuruga, Tohru Kiyono, Michiaki Matsushita, Tomosaburo Takahashi, Hironori Kasai, Shuichiro Matsumoto, Satoru Todo Cell transplantation 2008 new
Design and synthesis of dual inhibitors of HIV reverse transcriptase and integrase: introducing a diketoacid functionality into delavirdine. Zhengqiang Wang, Robert Vince Bioorganic & medicinal chemistry 2008 pols set
Detection and distribution of rotavirus in municipal sewage treatment plants (STPs) and surface water in Beijing. Xiao Q He, Li Cheng, Wei Li, Xiang M Xie, Mei Ma, Zi J Wang Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 2008 new
Synthesis of pyrimidine and quinolone conjugates as a scaffold for dual inhibitors of HIV reverse transcriptase and integrase. Zhengqiang Wang, Robert Vince Bioorganic & medicinal chemistry letters 2008 pols set
The replicative DNA polymerase of herpes simplex virus 1 exhibits apurinic/apyrimidinic and 5'-deoxyribose phosphate lyase activities. Federica Bogani, Paul E Boehmer Proceedings of the National Academy of Sciences of the United States of America 2008 new
DNA polymerase eta reduces the gamma-H2AX response to psoralen interstrand crosslinks in human cells. Seiki Mogi, Christina E Butcher, Dennis H Oh Exp Cell Res 2008 new
Changes in heparan sulfate are associated with delayed wound repair, altered cell migration, adhesion and contractility in the galactosyltransferase I (beta4GalT-7) deficient form of Ehlers-Danlos syndrome. Matthias Götte, Dorothe Spillmann, George W Yip, Elly Versteeg, Frank G Echtermeyer, Toin H van Kuppevelt, Ludwig Kiesel Hum Mol Genet 2008 new
Duality of polynucleotide substrates for Phi29 DNA polymerase: 3'-->5' RNase activity of the enzyme. Arunas Lagunavicius, Zivile Kiveryte, Vilma Zimbaite-Ruskuliene, Tomas Radzvilavicius, Arvydas Janulaitis RNA 2008 partial results
Early upregulation of cyclooxygenase-2 in human papillomavirus type 16 and telomerase-induced immortalization of human esophageal epithelial cells. Ze-Hao Zhuang, Sai-Wah Tsao, Wen Deng, Ji-De Wang, Harry Hua-Xiang Xia, Hua He, Hui-Chen Feng, Li-Dong Wang, Qing Gu, S-K Lam, Marie Chia-Mi Lin, Hsiang-Fu Kung, Benjamin Chun-Yu Wong Journal of gastroenterology and hepatology 2008 new
Proteomic analysis of human bone marrow mesenchymal stem cells transduced with human telomerase reverse transcriptase gene during proliferation. G P Huang, Z J Pan, J P Huang, J F Yang, C J Guo, Y G Wang, Q Zheng, R Chen, Y L Xu, G Z Wang, Y M Xi, D Shen, J Jin, J F Wang Cell proliferation 2008 new
Mechanism of double-base lesion bypass catalyzed by a Y-family DNA polymerase. Jessica A Brown, Sean A Newmister, Kevin A Fiala, Zucai Suo Nucleic acids research 2008 topics set
DNA polymerase theta (POLQ) can extend from mismatches and from bases opposite a (6-4) photoproduct. Masayuki Seki, Richard D Wood DNA repair 2008 new
Translesion synthesis of 7,8-dihydro-8-oxo-2'-deoxyguanosine by DNA polymerase eta in vivo. Dong-Hyun Lee, Gerd P Pfeifer Mutation research 2008 new
High-fidelity DNA polymerase enhances the sensitivity of a peptide nucleic acid clamp PCR assay for K-ras mutations. Bjørnar Gilje, Reino Heikkilä, Satu Oltedal, Kjersti Tjensvoll, Oddmund Nordgård J Mol Diagn 2008 new
[Activity of error-prone DNA polymerase iota in different periods of house mouse Mus musculus ontogeny]. Alena V Makarova, Leonid V Gening, Irina V Makarova, Vyacheslav Z Tarantul Ontogenez 2008 new
Uracil recognition by replicative DNA polymerases is limited to the archaea, not occurring with bacteria and eukarya. Josephine Wardle, Peter M J Burgers, Isaac K O Cann, Kate Darley, Pauline Heslop, Erik Johansson, Li-Jung Lin, Peter McGlynn, Jonathan Sanvoisin, Carrie M W Stith, Bernard A Connolly Nucleic acids research 2008 new
Tolerance for 8-oxoguanine but not thymine glycol in alignment-based gap filling of partially complementary double-strand break ends by DNA polymerase lambda in human nuclear extracts. Rui-Zhe Zhou, Luis Blanco, Miguel Garcia-Diaz, Katarzyna Bebenek, Thomas A Kunkel, Lawrence F Povirk Nucleic acids research 2008 new
Requirement of Rad5 for DNA polymerase zeta-dependent translesion synthesis in Saccharomyces cerevisiae. Vincent Pagès, Anne Bresson, Narottam Acharya, Satya Prakash, Robert P P Fuchs, Louise Prakash Genetics 2008 new
Editing of misaligned 3'-termini by an intrinsic 3'-5' exonuclease activity residing in the PHP domain of a family X DNA polymerase. Benito Baños, José María Lázaro, Laurentino Villar, Margarita Salas, Miguel de Vega Nucleic acids research 2008 partial results
Structural insights on the pamoic acid and the 8 kDa domain of DNA polymerase beta complex: towards the design of higher-affinity inhibitors. Corinne Hazan, François Boudsocq, Virginie Gervais, Olivier Saurel, Marion Ciais, Christophe Cazaux, Jerzy Czaplicki, Alain Milon BMC Struct Biol 2008 new
A pre-RNA candidate revisited: both enantiomers of flexible nucleoside triphosphates are DNA polymerase substrates. Benjamin D Heuberger, Christopher Switzer Journal of the American Chemical Society 2008 new
Amino acid mutation N348I in the connection subdomain of human immunodeficiency virus type 1 reverse transcriptase confers multiclass resistance to nucleoside and nonnucleoside reverse transcriptase inhibitors. Atsuko Hachiya, Eiichi N Kodama, Stefan G Sarafianos, Matthew M Schuckmann, Yasuko Sakagami, Masao Matsuoka, Masafumi Takiguchi, Hiroyuki Gatanaga, Shinichi Oka J Virol 2008 topics set
Synthesis and DNA-polymerase incorporation of colored 4-selenothymidine triphosphate for polymerase recognition and DNA visualization. Julianne Caton-Williams, Zhen Huang Angew Chem Int Ed Engl 2008 new
The Asp285 variant of DNA polymerase beta extends mispaired primer termini via increased nucleotide binding. Drew L Murphy, Jessica L Kosa, Joachim Jaeger, Joann B Sweasy Biochemistry 2008 new
Cidofovir diphosphate inhibits molluscum contagiosum virus DNA polymerase activity. Takahiro Watanabe, Kunihiko Tamaki J Invest Dermatol 2008 new
Analysis of processivity of mungbean dideoxynucleotide-sensitive DNA polymerase and detection of the activity and expression of the enzyme in the meristematic and meiotic tissues and following DNA damaging agent. Sujit Roy, Swarup Roy Choudhury, Dibyendu Narayan SenGupta Arch Biochem Biophys 2008 new
Structure of PolC reveals unique DNA binding and fidelity determinants. Ronald J Evans, Douglas R Davies, James M Bullard, Jeffrey Christensen, Louis S Green, Joseph W Guiles, Janice D Pata, Wendy K Ribble, Nebojsa Janjic, Thale C Jarvis Proceedings of the National Academy of Sciences of the United States of America 2008 topics set
Distinct double- and single-stranded DNA binding of E. coli replicative DNA polymerase III alpha subunit. Micah J McCauley, Leila Shokri, Jana Sefcikova, Ceslovas Venclovas, Penny J Beuning, Mark C Williams ACS Chem Biol 2008 pols set
Near full-length genomic analysis of a novel subtype A1/C recombinant HIV type 1 isolate from Canada. Michel L Ntemgwa, Thomas D'Aquin Toni, Bluma G Brenner, Jean-Pierre Routy, Daniela D Moisi, Maureen Oliveira, Mark A. Wainberg AIDS research and human retroviruses 2008 pols set
2-(2,6-Dihalo-phenyl)-3-heteroaryl-2-ylmethyl-1, 3-thiazolidin-4-ones: anti-HIV agents. Ravindra K Rawal, Rajkamal Tripathi, Smitha Kulkarni, R Paranjape, S B Katti, Christophe Pannecouque, Erik De Clercq Chemical biology & drug design 2008 pols set
Design and synthesis of 2-(2,6-dibromophenyl)-3-heteroaryl-1,3-thiazolidin-4-ones as anti-HIV agents. Ravindra K Rawal, Rajkamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq European journal of medicinal chemistry 2008 pols set
Efficient and accurate bypass of N2-(1-carboxyethyl)-2'-deoxyguanosine by DinB DNA polymerase in vitro and in vivo. Bifeng Yuan, Huachuan Cao, Yanan Jiang, Haizheng Hong, Yinsheng Wang Proceedings of the National Academy of Sciences of the United States of America 2008 new
Increased expression of the adult stem cell marker Musashi-1 in endometriosis and endometrial carcinoma. Matthias Götte, M Wolf, A Staebler, O Buchweitz, Reinhard Kelsch, A N Schüring, Ludwig Kiesel J Pathol 2008 new
Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase by a stavudine analogue, 4'-ethynyl stavudine triphosphate. Guangwei Yang, Jianhong Wang, Yao Cheng, Ginger E Dutschman, Hiromichi Tanaka, Masanori Baba, Yung-Chi Cheng Antimicrobial agents and chemotherapy 2008 pols set
Crystal engineering of HIV-1 reverse transcriptase for structure-based drug design. Joseph David Bauman, Kalyan Das, William C Ho, Mukta Baweja, Daniel M Himmel, Arthur D Clark, Deena A Oren, Paul L Boyer, Stephen H Hughes, Aaron J Shatkin, Edward Arnold Nucleic acids research 2008 partial results
Emerging antiviral drugs. Erik De Clercq Expert opinion on emerging drugs 2008 pols set
An AP endonuclease 1-DNA polymerase beta complex: theoretical prediction of interacting surfaces. Alexej Abyzov, Alper Uzun, Phyllis R Strauss, Valentin A Ilyin PLoS Comput Biol 2008 new
Stem-loop silencing reveals that a third mitochondrial DNA polymerase, POLID, is required for kinetoplast DNA replication in trypanosomes. Julian Chandler, Anthula V Vandoros, Brian Mozeleski, Michele M Klingbeil Eukaryot Cell 2008 new
Recent advances in the research of HIV-1 RNase H inhibitors. Fang Yu, Xinyong Liu, Peng Zhan, Erik De Clercq Mini reviews in medicinal chemistry 2008 pols set
Mechanistic consequences of temperature on DNA polymerization catalyzed by a Y-family DNA polymerase. Kevin A Fiala, Shanen M Sherrer, Jessica A Brown, Zucai Suo Nucleic acids research 2008 topics set
REV1 restrains DNA polymerase zeta to ensure frame fidelity during translesion synthesis of UV photoproducts in vivo. Dávid Szüts, Adam P Marcus, Masayuki Himoto, Shigenori Iwai, Julian E Sale Nucleic acids research 2008 new
Characterization of a replicative DNA polymerase mutant with reduced fidelity and increased translesion synthesis capacity. Xuejun Zhong, Lars C Pedersen, Thomas A Kunkel Nucleic acids research 2008 topics set
Experimental evidence that a DNA polymerase can incorporate N7-platinated guanines to give platinated DNA. Michele Benedetti, Cosimo Ducani, Danilo Migoni, Daniela Antonucci, Vita M Vecchio, Antonella Ciccarese, Alessandro Romano, Tiziano Verri, Giuseppe Ciccarella, Francesco P Fanizzi Angew Chem Int Ed Engl 2008 new
Mechanism of antiviral drug resistance of vaccinia virus: identification of residues in the viral DNA polymerase conferring differential resistance to antipoxvirus drugs. Don B Gammon, Robert Snoeck, Pierre Fiten, Marcela Krecmerová, Antonín Holý, Erik De Clercq, Ghislain Opdenakker, David H Evans, Graciela Andrei J Virol 2008 complete David H Evans*
Mechanism and dynamics of translesion DNA synthesis catalyzed by the Escherichia coli Klenow fragment. Asim Sheriff, Edward Motea, Irene Lee, Anthony J Berdis Biochemistry 2008 pols set
Arabidopsis thaliana Y-family DNA polymerase eta catalyses translesion synthesis and interacts functionally with PCNA2. Heather J Anderson, Edward J Vonarx, Landon Pastushok, Mayu Nakagawa, Atsushi Katafuchi, Petr Grúz, Antonio Di Rubbo, Desma M Grice, Megan J Osmond, Ayako N Sakamoto, Takehiko Nohmi, Wei Xiao, Bernard A Kunz Plant J 2008 complete Bernard A Kunz*
Two translesion synthesis DNA polymerase genes, AtPOLH and AtREV1, are involved in development and UV light resistance in Arabidopsis. María Jesús Santiago, Encarna Alejandre-Durán, Andrés Muñoz-Serrano, Manuel Ruiz-Rubio J Plant Physiol 2008 new
Catalytic mechanism of human DNA polymerase lambda with Mg2+ and Mn2+ from ab initio quantum mechanical/molecular mechanical studies. G Andrés Cisneros, Lalith Perera, Miguel García-Díaz, Katarzyna Bebenek, Thomas A Kunkel, Lee G Pedersen DNA repair 2008 pols set
DNA polymerase beta fidelity: halomethylene-modified leaving groups in pre-steady-state kinetic analysis reveal differences at the chemical transition state. Christopher A Sucato, Thomas G Upton, Boris A Kashemirov, Jorge Osuna, Keriann Oertell, William A Beard, Samuel H Wilson, Jan Florián, Arieh Warshel, Charles E McKenna, Myron F Goodman Biochemistry 2008 new
Mechanisms by which herpes simplex virus DNA polymerase limits translesion synthesis through abasic sites. Yali Zhu, Liping Song, Jason Stroud, Deborah S Parris DNA repair 2008 new
Quantum mechanics/molecular mechanics investigation of the chemical reaction in Dpo4 reveals water-dependent pathways and requirements for active site reorganization. Yazhen Wang, Tamar Schlick Journal of the American Chemical Society 2008 topics set
Intrinsic 5'-deoxyribose-5-phosphate lyase activity in Saccharomyces cerevisiae Trf4 protein with a possible role in base excision DNA repair. Lionel Gellon, Dena R Carson, Jonathan P Carson, Bruce Demple DNA repair 2008 topics set
The I260Q variant of DNA polymerase beta extends mispaired primer termini due to its increased affinity for deoxynucleotide triphosphate substrates. Shibani Dalal, Daniela Starcevic, Joachim Jaeger, Joann B Sweasy Biochemistry 2008 new
DNA polymerase-catalyzed DNA network growth. Sascha Keller, Jianhong Wang, Madhaviah Chandra, Rüdiger Berger, Andreas Marx Journal of the American Chemical Society 2008 new
Use of 2-aminopurine fluorescence to study the role of the beta hairpin in the proofreading pathway catalyzed by the phage T4 and RB69 DNA polymerases. Usharani Subuddhi, Matthew Hogg, Linda J Reha-Krantz Biochemistry 2008 complete
Reduced efficiency and increased mutagenicity of translesion DNA synthesis across a TT cyclobutane pyrimidine dimer, but not a TT 6-4 photoproduct, in human cells lacking DNA polymerase eta. Ayal Hendel, Omer Ziv, Quentin Gueranger, Nicholas E Geacintov, Zvi Livneh DNA repair 2008 new
Vinylogous ureas as a novel class of inhibitors of reverse transcriptase-associated ribonuclease H activity. Michaela Wendeler, Hsiu-Fang Lee, Alun Bermingham, Jennifer T Miller, Oleg Chertov, Marion K Bona, Noel S Baichoo, Maryam Ehteshami, John A Beutler, Barry R O'Keefe, Matthias Götte, Mamuka Kvaratskhelia, Stuart F J Le Grice ACS Chem Biol 2008 new
Specificity of mutations induced by incorporation of oxidized dNTPs into DNA by human DNA polymerase eta. Katsuhiko Hidaka, Masami Yamada, Hiroyuki Kamiya, Chikahide Masutani, Hideyoshi Harashima, Fumio Hanaoka, Takehiko Nohmi DNA repair 2008 pols set
Overproduction of Escherichia coli DNA polymerase DinB (Pol IV) inhibits replication fork progression and is lethal. Kaori Uchida, Asako Furukohri, Yutaka Shinozaki, Tetsuya Mori, Daichi Ogawara, Shigehiko Kanaya, Takehiko Nohmi, Hisaji Maki, Masahiro Tatsumi Akiyama Molecular microbiology 2008 pols set
DNA polymerase delta is highly processive with proliferating cell nuclear antigen and undergoes collision release upon completing DNA. Lance D Langston, Mike E O'Donnell The Journal of biological chemistry 2008 topics set
Human DNA polymerase eta activity and translocation is regulated by phosphorylation. Yih-Wen Chen, James E Cleaver, Zafer Hatahet, Richard E Honkanen, Jang-Yang Chang, Yun Yen, Kai-Ming Chou Proceedings of the National Academy of Sciences of the United States of America 2008 pols set
Contrasting drug resistance phenotypes resulting from cytomegalovirus DNA polymerase mutations at the same exonuclease locus. Sunwen Chou, Gail Marousek, Shaobing Li, Adriana Weinberg J Clin Virol 2008 new
Juvenile Alpers disease. Esko Wiltshire, Guido Davidzon, Salvatore DiMauro, Hasan O Akman, Lynette Sadleir, Lindsay Haas, Jane Zuccollo, Alison McEwen, David R Thorburn Archives of neurology 2008 pols set
[Down-regulative expression of microRNAs cluster in human colon tumorigenesis]. Yi Ba, Xing Cai, Xi Chen, Yuan Yin, Yongqing Zhang, Chen-yu Zhang Zhonghua yi xue za zhi 2008 new
Intrinsic properties of the two replicative DNA polymerases of Pyrococcus abyssi in replicating abasic sites: possible role in DNA damage tolerance? Adeline Palud, Giuseppe Villani, Stéphane L'Haridon, Joël Querellou, Jean-Paul Raffin, Ghislaine Henneke Molecular microbiology 2008 partial results
POLG1 mutations manifesting as autosomal recessive axonal Charcot-Marie-Tooth disease. Timothy Harrower, Joanna D Stewart, Gavin Hudson, Henry Houlden, Graham Warner, Dominic G O'Donovan, Leslie J Findlay, Robert W Taylor, Rajith De Silva, Patrick F Chinnery Archives of neurology 2008 pols set
Mutational specificity of gamma-radiation-induced guanine-thymine and thymine-guanine intrastrand cross-links in mammalian cells and translesion synthesis past the guanine-thymine lesion by human DNA polymerase eta. Laureen C Colis, Paromita Raychaudhury, Ashis K Basu Biochemistry 2008 complete Ashis K Basu*
X-ray structure of the complex of regulatory subunits of human DNA polymerase delta. Andrey G Baranovskiy, Nigar D Babayeva, Victoria G Liston, Igor B Rogozin, Eugene V Koonin, Youri I Pavlov, Dmitry G Vassylyev, Tahir H Tahirov Cell Cycle 2008 pols set
Fingers-closing and other rapid conformational changes in DNA polymerase I (Klenow fragment) and their role in nucleotide selectivity. Catherine M Joyce, Olga Potapova, Angela M DeLucia, Xuanwei Huang, Vandana Purohit Basu, Nigel D F Grindley Biochemistry 2008 complete
DNA polymerase epsilon: a polymerase of unusual size (and complexity). Zachary F Pursell, Thomas A Kunkel Prog Nucleic Acid Res Mol Biol 2008 new
Delayed chain termination protects the anti-hepatitis B virus drug entecavir from excision by HIV-1 reverse transcriptase. Egor P Tchesnokov, Aleksandr Obikhod, Raymond F Schinazi, Matthias Götte The Journal of biological chemistry 2008 complete Bruno Marchand
New strategies for DNA polymerase library screening. Ramon Kranaster, Andreas Marx Nucleic Acids Symp Ser (Oxf) 2008 new
Altered order of substrate binding by DNA polymerase X from African Swine Fever virus. Sandeep Kumar, Marina Bakhtina, Ming-Daw Tsai Biochemistry 2008 new
Utilization of a deoxynucleoside diphosphate substrate by HIV reverse transcriptase. Scott J Garforth, Michael A. Parniak, Vinayaka R Prasad PloS one 2008 pols set
Molecular and clinical genetics of mitochondrial diseases due to POLG mutations. Lee-Jun C Wong, Robert K Naviaux, Nicola Brunetti-Pierri, Qing Zhang, Eric S Schmitt, Cavatina K Truong, Margherita Milone, Bruce H Cohen, Beverly Wical, Jaya Ganesh, Alice A Basinger, Barbara K Burton, Kathryn Swoboda, Donald L Gilbert, Adeline Vanderver, Russell P Saneto, Bruno Maranda, Georgianne Arnold, Jose E Abdenur, Paula J Waters, William C Copeland Human mutation 2008 pols set
Association of the polymorphism of the CAG repeat in the mitochondrial DNA polymerase gamma gene (POLG) with testicular germ-cell cancer. M Blomberg Jensen, Henrik Leffers, Jørgen H Petersen, G Daugaard, Niels E Skakkebaek, Ewa Rajpert-De Meyts Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008 new
Association between trinucleotide CAG repeats of the DNA polymerase gene (POLG) with age of onset of Iranian Friedreich's ataxia patients. Mohammad Mehdi Heidari, Massoud Houshmand, Saman Hosseinkhani, Shahriar Nafissi, Barbara Scheiber-Mojdehkar, Mehri Khatami Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2008 new
Alpers syndrome with prominent white matter changes. Xinhua Bao, Ye Wu, Lee-Jun C Wong, Yongqing Zhang, Hui Xiong, Ping-Chieh Chou, Cavatina K Truong, Yanan Jiang, Jiong Qin, Yun Yuan, Qing Lin, Xiaoming Wu Brain & development 2008 pols set
A dynamic polymerase exchange with Escherichia coli DNA polymerase IV replacing DNA polymerase III on the sliding clamp. Asako Furukohri, Myron F Goodman, Hisaji Maki The Journal of biological chemistry 2008 pols set
DNA polymerases and human disease. Lawrence A Loeb, Raymond J Monnat Nature reviews. Genetics 2008 new
The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases. Scott D McCulloch, Thomas A Kunkel Cell research 2008 partial results
Bisphosphonate inhibitors of ATP-mediated HIV-1 reverse transcriptase catalyzed excision of chain-terminating 3'-azido, 3'-deoxythymidine: a QSAR investigation. Yongcheng Song, Julian M W Chan, Zev Tovian, Aaron Secrest, Eva Nagy, Kilannin Krysiak, Kyle Bergan, Michael A. Parniak, Eric Oldfield Bioorganic & medicinal chemistry 2008 pols set
Two novel POLG1 mutations in a patient with progressive external ophthalmoplegia, levodopa-responsive pseudo-orthostatic tremor and parkinsonism. Federica Invernizzi, Sara Varanese, Astrid Thomas, Franco Carrara, Marco Onofrj, Massimo Zeviani Neuromuscular disorders : NMD 2008 pols set
Parkinsonism associated with the homozygous W748S mutation in the POLG1 gene. Anne M Remes, Reetta Hinttala, M Kärppä, Heidi Soini, R Takalo, Johanna Uusimaa, Kari Majamaa Parkinsonism & related disorders 2008 pols set
Clonally expanded mitochondrial DNA mutations in epileptic individuals with mutated DNA polymerase gamma. Gábor Zsurka, Miriam Baron, Joanna D Stewart, Cornelia Kornblum, Monika Bös, Robert Sassen, Robert W Taylor, Christian E Elger, Patrick F Chinnery, Wolfram S Kunz Journal of neuropathology and experimental neurology 2008 pols set
Characterization of a Bacillus subtilis 64-kDa DNA polymerase X potentially involved in DNA repair. Benito Baños, José María Lázaro, Laurentino Villar, Margarita Salas, Miguel de Vega Journal of molecular biology 2008 complete
New DNA polymerase IIIC inhibitors: 3-subtituted anilinouracils with potent antibacterial activity in vitro and in vivo. Niels Svenstrup, Kerstin Ehlert, Christoph Ladel, Alexander Kuhl, Dieter Häbich ChemMedChem 2008 new
Evidence for lesion bypass by yeast replicative DNA polymerases during DNA damage. Nasim Sabouri, Jörgen Viberg, Dinesh Kumar Goyal, Erik Johansson, Andrei Chabes Nucleic acids research 2008 pols set
Kinetic investigation of the inhibitory effect of gemcitabine on DNA polymerization catalyzed by human mitochondrial DNA polymerase. Jason D Fowler, Jessica A Brown, Kenneth A Johnson, Zucai Suo The Journal of biological chemistry 2008 pols set
DNA polymerase delta is preferentially recruited during homologous recombination to promote heteroduplex DNA extension. Laurent Maloisel, Francis Fabre, Serge Gangloff Molecular and cellular biology 2008 new
Exonuclease activity of proofreading DNA polymerases is at the origin of artifacts in molecular profiling studies. J Gury, L Zinger, L Gielly, P Taberlet, RA Geremia Electrophoresis 2008 topics set
Role of induced fit in enzyme specificity: a molecular forward/reverse switch. Kenneth A Johnson The Journal of biological chemistry 2008 new
Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding. Kristie D Goodwin, Mark A Lewis, Eric C Long, Millie M Georgiadis Proceedings of the National Academy of Sciences of the United States of America 2008 topics set
Exonuclease removal of dideoxycytidine (zalcitabine) by the human mitochondrial DNA polymerase. Jeremiah W Hanes, Kenneth A Johnson Antimicrobial agents and chemotherapy 2008 new
Low-fidelity DNA synthesis by human DNA polymerase theta. Mercedes E Arana, Masayuki Seki, Richard D Wood, Igor B Rogozin, Thomas A Kunkel Nucleic acids research 2008 partial results
Human telomerase reverse transcriptase expression correlates with vascular endothelial growth factor-promoted tumor cell proliferation in prostate cancer. Jie Tang, Zhengqiang Wang, Xincang Li, Jinming Li, Huaiyin Shi Artificial cells, blood substitutes, and immobilization biotechnology 2008 new
Microbial subversion of heparan sulfate proteoglycans. Ye Chen, Matthias Götte, Jianhua Liu, Pyong Woo Park Mol Cells 2008 new
Regulation of Saccharomyces cerevisiae DNA polymerase eta transcript and protein. Ritu Pabla, Donald Rozario, Wolfram Siede Radiat Environ Biophys 2008 pols set
The Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase delta. Nives Selak, Csanád Z Bachrati, Igor V Shevelev, Tobias Dietschy, Barbara van Loon, Anette Jacob, Ulrich Hübscher, Joerg D Hoheisel, Ian D Hickson, Igor Stagljar Nucleic acids research 2008 pols set
Synthesis and anti-HIV evaluation of novel 1,3-disubstituted thieno[3,2-c][1,2,6]thiadiazin-4(3H)-one 2,2-dioxides(TTDDs). Yongqiang Lin, Xinyong Liu, Renzhang Yan, Jinming Li, Christophe Pannecouque, Myriam Witvrouw, Erik De Clercq Bioorganic & medicinal chemistry 2008 new
Over-expression of the catalytic core of mitochondrial DNA (mtDNA) polymerase in the nervous system of Drosophila melanogaster reduces median life span by inducing mtDNA depletion. Francisco Martínez-Azorín, Manuel Calleja, Rosana Hernández-Sierra, Carol L Farr, Laurie S Kaguni, Rafael Garesse Journal of neurochemistry 2008 new
Division of labor at the eukaryotic replication fork. Stephanie A Nick McElhinny, Dmitry A Gordenin, Carrie M W Stith, Peter M J Burgers, Thomas A Kunkel Molecular cell 2008 new
Cidofovir and (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine are highly effective inhibitors of vaccinia virus DNA polymerase when incorporated into the template strand. Wendy C Magee, Kathy A Aldern, Karl Y Hostetler, David H Evans Antimicrob Agents Chemother 2008 complete David H Evans*
Inhibition of HSV-1 replication and HSV DNA polymerase by the chloroxoquinolinic ribonucleoside 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid and its aglycone. Thiago Moreno L Souza, Maria Cecilia Bastos V De Souza, Vitor F Ferreira, Carla Veronica B Santos Canuto, Isakelly Pereira Marques, Carlos Frederico L Fontes, Izabel C P P Frugulhetti Antiviral Res 2008 new
Inhibition of tubulin polymerization by select alkenyldiarylmethanes. Matthew D Cullen, Taradas Sarkar, Ernest Hamel, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman Bioorganic & medicinal chemistry letters 2008 new
A comparison of BRCT domains involved in nonhomologous end-joining: introducing the solution structure of the BRCT domain of polymerase lambda. Geoffrey A Mueller, Andrea F Moon, Eugene F DeRose, Jody M Havener, Dale A Ramsden, Lars C Pedersen, Robert E London DNA repair 2008 new
Novel indole-3-sulfonamides as potent HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs). Zhijian Zhao, Scott E Wolkenberg, Philip E J Sanderson, Meiqing Lu, Vandna Munshi, Gregory Moyer, Meizhen Feng, Anthony V Carella, Linda T Ecto, Lori J Gabryelski, Ming-Tain Lai, Sridar G Prasad, Youwei Yan, Georgia B McGaughey, Michael D Miller, Craig W Lindsley, George D Hartman, Joseph P Vacca, Theresa M Williams Bioorganic & medicinal chemistry letters 2008 partial results
Novel evidences for a tumor suppressor role of Rev3, the catalytic subunit of Pol zeta. J-M Brondello, Marie-Jeanne Pillaire, C Rodriguez, P-A Gourraud, Janick Selves, Christophe Cazaux, J Piette Oncogene 2008 topics set
Biochemical studies with DNA polymerase beta and DNA polymerase beta-PAK of Trypanosoma cruzi suggest the involvement of these proteins in mitochondrial DNA maintenance. Débora de Oliveira Lopes, Bruno Luiz Fonseca Schamber-Reis, Carlos Gustavo Regis-da-Silva, Matheus Andrade Rajão, Wanderson Duarte DaRocha, Andréa Mara Macedo, Glória Regina Franco, Sheila Cristina Nardelli, Sérgio Schenkman, Jean-Sébastien Hoffmann, Christophe Cazaux, Sérgio Danilo Junho Pena, Santuza Maria Ribeiro Teixeira, Carlos Renato Machado DNA repair 2008 complete Carlos Renato Machado*
The N-clasp of human DNA polymerase kappa promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesions. Lei Jia, Nicholas E Geacintov, Suse Broyde Nucleic acids research 2008 pols set
Molecular modeling and functional characterization of the monomeric primase-polymerase domain from the Sulfolobus solfataricus plasmid pIT3. S Prato, RM Vitale, P Contursi, G Lipps, M Saviano, M Rossi, S Bartolucci The FEBS journal 2008 topics set
Opposed steric constraints in human DNA polymerase beta and E. coli DNA polymerase I. Francesca Di Pasquale, Daniela Fischer, Dina Grohmann, Tobias Restle, Armin Geyer, Andreas Marx Journal of the American Chemical Society 2008 pols set
Mutation frequencies and spectra in DNA polymerase eta-deficient mice. Rita A Busuttil, Qingcong Lin, Peter J Stambrook, Raju Kucherlapati, Jan Vijg Cancer research 2008 new
Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpoint. Huiqiang Lou, Makiko Komata, Yuki Katou, Zhiyun Guan, Clara C Reis, Martin E Budd, Katsuhiko Shirahige, Judith L Campbell Molecular cell 2008 new
Human methyl purine DNA glycosylase and DNA polymerase beta expression collectively predict sensitivity to temozolomide. Ram N Trivedi, Xiao-Hong Wang, Elena Jelezcova, Eva M Goellner, Jiang-bo Tang, Robert W Sobol Mol Pharmacol 2008 new
[Mutations of HBV polymerase gene sequence in lamivudine-resistant chronic hepatitis B patients]. Cheng Wang, Jian Sun, Jin-jun Chen, Zhan-hui Wang, Jin-lin Hou Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2008 new
Structure of a mutant form of proliferating cell nuclear antigen that blocks translesion DNA synthesis. Bret D Freudenthal, S Ramaswamy, Manju M Hingorani, M Todd Washington Biochemistry 2008 new
Domain architecture and biochemical characterization of vertebrate Mcm10. PD Robertson, Eric M Warren, Haijiang Zhang, DB Friedman, JW Lary, JL Cole, AV Tutter, JC Walter, Ellen Fanning, Brandt F Eichman The Journal of biological chemistry 2008 topics set
Enzymatic synthesis of structure-free DNA with pseudo-complementary properties. Georges Lahoud, Victor Timoshchuk, Alexandre Lebedev, Miguel de Vega, Margarita Salas, Khalil Arar, Ya-Ming Hou, Howard Gamper Nucleic acids research 2008 topics set
A new family of polymerases related to superfamily A DNA polymerases and T7-like DNA-dependent RNA polymerases. Lakshminarayan M Iyer, Saraswathi Abhiman, L Aravind Biol Direct 2008 topics set
Induction of a:T mutations is dependent on cellular environment but independent of mutation frequency and target gene location. Akiko Ukai, Konomi Ishimaru, Rika Ouchida, Hiromi Mori, Chie Kano, Toshiyuki Moritan, Ji-Yang Wang Journal of immunology (Baltimore, Md. : 1950) 2008 new
An investigation of the effects of nanosize delivery system for antisense oligonucleotide on esophageal squamous cancer cells. Huixiang Li, Jin Wang, Tianyang Zhou, Yongqing Zhang, Zhenzhong Zhang Cancer biology & therapy 2008 new
DNA polymerase zeta (pol zeta) in higher eukaryotes. GregoryN Gan, JohnP Wittschieben, BirgitteØ Wittschieben, RichardD Wood Cell research 2008 topics set
Reduced levels of DNA polymerase delta induce chromosome fragile site instability in yeast. Francene J Lemoine, Natasha P Degtyareva, Robert J Kokoska, Thomas D Petes Molecular and cellular biology 2008 new
Triazole derivatives as non-nucleoside inhibitors of HIV-1 reverse transcriptase--structure-activity relationships and crystallographic analysis. Thorsten A Kirschberg, Mini Balakrishnan, Wei Huang, Rebecca Hluhanich, Nilima Kutty, Albert C Liclican, Damian J McColl, Neil H Squires, Eric B Lansdon Bioorganic & medicinal chemistry letters 2008 partial results
Structural insights into the generation of single-base deletions by the Y family DNA polymerase dbh. Ryan C Wilson, Janice D Pata Molecular cell 2008 topics set
Connection domain mutations N348I and A360V in HIV-1 reverse transcriptase enhance resistance to 3'-azido-3'-deoxythymidine through both RNase H-dependent and -independent mechanisms. Maryam Ehteshami, Greg L Beilhartz, Brian J Scarth, Egor P Tchesnokov, Suzanne McCormick, Brian Wynhoven, P Richard Harrigan, Matthias Götte The Journal of biological chemistry 2008 topics set
Effect of dehydroaltenusin-C12 derivative, a selective DNA polymerase alpha inhibitor, on DNA replication in cultured cells. Isoko Kuriyama, Takeshi Mizuno, Keishi Fukudome, Kouji Kuramochi, Kazunori Tsubaki, Takeo Usui, Naoko Imamoto, Kengo Sakaguchi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Molecules 2008 complete Takeshi Mizuno*
Quantification of VEGF-C expression in canine mammary tumours. C Qiu, D D Lin, H H Wang, C H Qiao, Jiqun Wang, Tao Zhang Australian veterinary journal 2008 new
Two-dimensional infrared spectra reveal relaxation of the nonnucleoside inhibitor TMC278 complexed with HIV-1 reverse transcriptase. Chong Fang, Joseph David Bauman, Kalyan Das, Amanda Remorino, Edward Arnold, Robin M Hochstrasser Proceedings of the National Academy of Sciences of the United States of America 2008 pols set
Nucleotide selectivity opposite a benzo[a]pyrene-derived N2-dG adduct in a Y-family DNA polymerase: a 5'-slippage mechanism. Pingna Xu, Lida Oum, Nicholas E Geacintov, Suse Broyde Biochemistry 2008 topics set
Mutations M184V and Y115F in HIV-1 reverse transcriptase discriminate against "nucleotide-competing reverse transcriptase inhibitors". Maryam Ehteshami, Brian J Scarth, Egor P Tchesnokov, Chandravanu Dash, Stuart F J Le Grice, Sabine Hallenberger, Dirk Jochmans, Matthias Götte The Journal of biological chemistry 2008 topics set
Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside reverse transcriptase inhibitors. Anna-Maria Monforte, Angela Rao, Patrizia Logoteta, Stefania Ferro, Laura De Luca, Maria Letizia Barreca, Nunzio Iraci, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri Bioorganic & medicinal chemistry 2008 pols set
Discovery and optimization of pyridazinone non-nucleoside inhibitors of HIV-1 reverse transcriptase. Zachary K Sweeney, James P Dunn, Yingqian Li, Gabrielle M Heilek, Pete W Dunten, Todd R Elworthy, Xiaochun Han, Seth F Harris, Donald R Hirschfeld, J Heather Hogg, Walter Huber, Ann C Kaiser, Denis J Kertesz, Woongki Kim, Taraneh Mirzadegan, Michael G Roepel, Y David Saito, Tania M P C Silva, Steven Swallow, Jahari L Tracy, Armando Villasenor, Harit Vora, Amy S Zhou, Klaus Klumpp Bioorganic & medicinal chemistry letters 2008 partial results
The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations. Thomas J Tucker, Sandeep Saggar, John T Sisko, Robert M Tynebor, Theresa M Williams, Peter J Felock, Jessica A Flynn, Ming-Tain Lai, Yuexia Liang, Georgia B McGaughey, Meiquing Liu, Michael D Miller, Gregory Moyer, Vandna Munshi, Rebecca A Perlow-Poehnelt, Sridhar Prasad, Rosa Sanchez, Maricel Torrent, Joseph P Vacca, Bang-Lin Wan, Youwei Yan Bioorganic & medicinal chemistry letters 2008 partial results
Rapidly progressive neurological deterioration in a child with Alpers syndrome exhibiting a previously unremarkable brain MRI. Nicola Brunetti-Pierri, K Selby, M O'Sullivan, G Hendson, Cavatina K Truong, Paula J Waters, L-J Wong Neuropediatrics 2008 pols set
Characterization of plant XRCC1 and its interaction with proliferating cell nuclear antigen. Yukinobu Uchiyama, Yuko Suzuki, Kengo Sakaguchi Planta 2008 new
Multiple-sited amyloidosis in the upper aerodigestive tract: case report and literature review. Gustavo Haruo Passerotti, Marcello Caniello, Adriana Hachiya, Patrícia P Santoro, Rui Imamura, Domingos H Tsuji Braz J Otorhinolaryngol 2008 new
Biochemical evolution of DNA polymerase eta: properties of plant, human, and yeast proteins. Peter D Hoffman, Marc J Curtis, Shigenori Iwai, John B Hays Biochemistry 2008 new
The mitochondrial genome of the Basidiomycete fungus Pleurotus ostreatus (oyster mushroom). Yong Wang, Fanya Zeng, Chung Chau Hon, Yongqing Zhang, Frederick Chi Ching Leung FEMS microbiology letters 2008 new
Comparison of the growth kinetics of neuropathogenic and nonneuropathogenic equid herpesvirus type 1 (EHV-1) strains in cultured murine neuronal cells and the relevance of the D/N(752) coding change in DNA polymerase gene (ORF30). Souichi Yamada, Tomio Matsumura, Koji Tsujimura, Tsuyoshi Yamaguchi, Kenji Ohya, Hideto Fukushi J Vet Med Sci 2008 new
Insights into the replisome from the structure of a ternary complex of the DNA polymerase III alpha-subunit. Richard A Wing, Scott Bailey, Thomas A Steitz Journal of molecular biology 2008 topics set
DNA polymerase I-mediated translesion synthesis in RecA-independent DNA interstrand cross-link repair in E. coli. Laura Zietlow, Tadayoshi Bessho Biochemistry 2008 complete Tadayoshi Bessho*
Crystal structure of Pfu, the high fidelity DNA polymerase from Pyrococcus furiosus. Suhng Wook Kim, Dong-Uk Kim, Jin Kwang Kim, Lin-Woo Kang, Hyun-Soo Cho Int J Biol Macromol 2008 topics set
A tandem repeat of human telomerase reverse transcriptase (hTERT) and risk of breast cancer development and metastasis in Chinese women. Yan Wang, Zhibin Hu, Jie Liang, Zhengqiang Wang, Jinhai Tang, Shui Wang, Xuechen Wang, Jianwei Qin, Xinru Wang, Hongbing Shen Carcinogenesis 2008 new
Substitution of a residue contacting the triphosphate moiety of the incoming nucleotide increases the fidelity of yeast DNA polymerase zeta. Craig A Howell, Christine M Kondratick, M Todd Washington Nucleic acids research 2008 topics set
Identification of a new motif required for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I (Klenow fragment): the RRRY motif is necessary for the binding of single-stranded DNA substrate and the template strand of the mismatched duplex. Pinky Kukreti, Kamalendra Singh, Amit Ketkar, Mukund J Modak The Journal of biological chemistry 2008 complete Mukund J Modak*
Nucleoside reverse transcriptase inhibitors and their phosphorylated metabolites in human immunodeficiency virus-infected human matrices. Jiaping Lai, Jun Wang, Zongwei Cai Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008 pols set
Inhibition of herpes simplex virus type 1 by small interfering RNA. Y Q Zhang, W Lai, H Li, G Li Clinical and experimental dermatology 2008 new
Genetic analysis reveals an intrinsic property of the germinal center B cells to generate A:T mutations. Rika Ouchida, Akiko Ukai, Hiromi Mori, Kiyoko Kawamura, Martijn E T Dollé, Masatoshi Tagawa, Akemi Sakamoto, Takeshi Tokuhisa, Tadashi Yokosuka, Takashi Saito, Masayuki Yokoi, Fumio Hanaoka, Jan Vijg, Ji-Yang Wang DNA repair 2008 new
Translesion synthesis across the (6-4) photoproduct and its Dewar valence isomer by the Y-family and engineered DNA polymerases. Junpei Yamamoto, David Loakes, Chikahide Masutani, Shizu Simmyo, Kumiko Urabe, Fumio Hanaoka, Philipp Holliger, Shigenori Iwai Nucleic acids symposium series (2004) 2008 pols set
Eutherians intrinsically run a higher risk of replication deficiency. Masaharu Takemura Bio Systems 2008 new
RNA primer handoff in bacteriophage T4 DNA replication: the role of single-stranded DNA-binding protein and polymerase accessory proteins. Scott W Nelson, Ravindra Kumar, Stephen J Benkovic The Journal of biological chemistry 2008 topics set
Solution structures of 2 : 1 and 1 : 1 DNA polymerase-DNA complexes probed by ultracentrifugation and small-angle X-ray scattering. Kuo-Hsiang Tang, Marc Niebuhr, Ann Aulabaugh, Ming-Daw Tsai Nucleic acids research 2008 new
Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors. Jingshan Ren, Phillip P Chamberlain, Anna Stamp, Steven A Short, Kurt L Weaver, Karen R Romines, Richard J Hazen, Andrew Freeman, Robert G Ferris, C Webster Andrews, Lawrence R Boone, Joseph H Chan, David K Stammers J Med Chem 2008 partial results
Effects of mutations in the connection and RNase H domains of HIV-1 reverse transcriptase on drug susceptibility. Maryam Ehteshami, Matthias Götte AIDS Rev 2008 topics set
Replication bypass of interstrand cross-link intermediates by Escherichia coli DNA polymerase IV. Anuradha Kumari, Irina G Minko, Michael B Harbut, Steven E Finkel, Myron F Goodman, R Stephen Lloyd The Journal of biological chemistry 2008 pols set
XRCC1 and DNA polymerase beta in cellular protection against cytotoxic DNA single-strand breaks. Julie K Horton, Mary Watson, Donna F Stefanick, Daniel T Shaughnessy, Jack A Taylor, Samuel H Wilson Cell research 2008 new
Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes. Stella A Martomo, Huseyin Saribasak, Masayuki Yokoi, Fumio Hanaoka, Patricia J Gearhart DNA repair 2008 new
Use of RNAi in C. elegans. Tsuyoshi Ohkumo, Chikahide Masutani, Toshihiko Eki, Fumio Hanaoka Methods in molecular biology (Clifton, N.J.) 2008 new
Mutant DNA polymerase for improved detection of single-nucleotide variations in microarrayed primer extension. Ramon Kranaster, Patrick Ketzer, Andreas Marx Chembiochem 2008 new
Pif1 helicase directs eukaryotic Okazaki fragments toward the two-nuclease cleavage pathway for primer removal. MarieL Rossi, JasonE Pike, Wensheng Wang, PeterMJ Burgers, JudithL Campbell, RobertA Bambara The Journal of biological chemistry 2008 new
The enhanced DNA replication fidelity of a mutant herpes simplex virus type 1 DNA polymerase is mediated by an improved nucleotide selectivity and reduced mismatch extension ability. Wang Tian, Ying T Hwang, Charles B C Hwang J Virol 2008 new
Low levels of DNA polymerase alpha induce mitotic and meiotic instability in the ribosomal DNA gene cluster of Saccharomyces cerevisiae. Anne M Casper, Piotr A Mieczkowski, Malgorzata Gawel, Thomas D Petes PLoS Genet 2008 pols set
The effects of alternate polypurine tracts (PPTs) and mutations of sequences adjacent to the PPT on viral replication and cleavage specificity of the Rous sarcoma virus reverse transcriptase. Kevin W Chang, Jangsuk Oh, W Gregory Alvord, Stephen H Hughes Journal of virology 2008 new
Measurement of coronary calcium scores by electron beam computed tomography or exercise testing as initial diagnostic tool in low-risk patients with suspected coronary artery disease. Christiane A Geluk, Riksta Dikkers, Patrick J Perik, René A Tio, Marco J W Götte, Hans L Hillege, Rozemarijn Vliegenthart, Janneke B Houwers, Tineke P Willems, Matthijs Oudkerk, Felix Zijlstra Eur Radiol 2008 new
Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp. Roxana E Georgescu, Olga Yurieva, Seung-Sup Kim, John Kuriyan, Xiang-Peng Kong, Mike E O'Donnell Proceedings of the National Academy of Sciences of the United States of America 2008 topics set
Targeting human DNA polymerase alpha for the inhibition of keratinocyte proliferation. Part 1. Homology model, active site architecture and ligand binding. Anja Richartz, Monika Höltje, Birte Brandt, Monika Schäfer-Korting, Hans-Dieter Höltje J Enzyme Inhib Med Chem 2008 pols set
AAV-mediated TRAIL gene expression driven by hTERT promoter suppressed human hepatocellular carcinoma growth in mice. Yongqing Zhang, Hong Ma, Jinchun Zhang, Shilian Liu, Yanxin Liu, Dexian Zheng Life sciences 2008 new
Hymenoic acid, a novel specific inhibitor of human DNA polymerase lambda from a fungus of Hymenochaetaceae sp. Masayuki Nishida, Noriko Ida, Mao Horio, Toshifumi Takeuchi, Shinji Kamisuki, Hiroshi Murata, Kouji Kuramochi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Bioorg Med Chem 2008 pols set
Interaction between DNA Polymerase lambda and RPA during translesion synthesis. Yu S Krasikova, Ekaterina A Belousova, Natalia A Lebedeva, P E Pestryakov, Olga I Lavrik Biochemistry (Mosc) 2008 new
Incorrect nucleotide insertion at the active site of a G:A mismatch catalyzed by DNA polymerase beta. Ping Lin, Vinod K Batra, Lars C Pedersen, William A Beard, Samuel H Wilson, Lee G Pedersen Proceedings of the National Academy of Sciences of the United States of America 2008 topics set
Synthetic studies on kohamaic acids: synthesis of structurally simplified analogs of kohamaic acid A. Hirosato Takikawa, Naoki Kamatani, Kohei Nakanishi, Takuya Tashiro, Mitsuru Sasaki, Hiromi Yoshida, Yoshiyuki Mizushina Bioscience, biotechnology, and biochemistry 2008 new
HIV-1 reverse transcriptase connection subdomain mutations reduce template RNA degradation and enhance AZT excision. Krista A Delviks-Frankenberry, Galina N Nikolenko, Paul L Boyer, Stephen H Hughes, John M Coffin, Abhay Jere, Vinay K Pathak Proceedings of the National Academy of Sciences of the United States of America 2008 pols set
A highly conserved family of inactivated archaeal B family DNA polymerases. Igor B Rogozin, Kira S Makarova, Youri I Pavlov, Eugene V Koonin Biol Direct 2008 topics set
Single-stranded DNA-binding protein recruits DNA polymerase V to primer termini on RecA-coated DNA. Gali Arad, Ayal Hendel, Claus Urbanke, Ute Curth, Zvi Livneh The Journal of biological chemistry 2008 new
Escherichia coli mismatch repair protein MutL interacts with the clamp loader subunits of DNA polymerase III. Feng Li, Qin Liu, Yuan-Yuan Chen, Zi-Niu Yu, Zhi-Ping Zhang, Ya-Feng Zhou, Jiao-Yu Deng, Li-Jun Bi, Xian-En Zhang Mutation research 2008 pols set
Snapshots of a Y-family DNA polymerase in replication: substrate-induced conformational transitions and implications for fidelity of Dpo4. Jimson H Y Wong, Kevin A Fiala, Zucai Suo, Hong Ling Journal of molecular biology 2008 topics set
Induction of centrosome amplification and chromosome instability in p53-deficient lung cancer cells exposed to benzo[a]pyrene diol epoxide (B[a]PDE). Kazuya Shinmura, M Iwaizumi, H Igarashi, K Nagura, Hidetaka Yamada, Motoshi Suzuki, K Fukasawa, Haruhiko Sugimura The Journal of pathology 2008 new
1-deoxyrubralactone, a novel specific inhibitor of families X and Y of eukaryotic DNA polymerases from a fungal strain derived from sea algae. Mitsuki Naganuma, Masayuki Nishida, Kouji Kuramochi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Bioorganic & medicinal chemistry 2008 pols set
Identification of a Taq DNA polymerase inhibitor from the red seaweed Symphyocladia latiuscula. Hyung Joo Jin, Mi Young Oh, Deuk Hee Jin, Yong Ki Hong J Environ Biol 2008 pols set
Apparent defects in processive DNA synthesis, strand transfer, and primer elongation of Met-184 mutants of HIV-1 reverse transcriptase derive solely from a dNTP utilization defect. Lu Gao, Mark Nils Hanson, Mini Balakrishnan, Paul L Boyer, Bernard P Roques, Stephen H Hughes, Baek Kim, Robert A Bambara The Journal of biological chemistry 2008 pols set
Mutations in the U5 region adjacent to the primer binding site affect tRNA cleavage by human immunodeficiency virus type 1 reverse transcriptase in vivo. Jangsuk Oh, Mary Jane McWilliams, John G Julias, Stephen H Hughes Journal of virology 2008 pols set
Replication protein A and proliferating cell nuclear antigen coordinate DNA polymerase selection in 8-oxo-guanine repair. Giovanni Maga, Emmanuele Crespan, Ursula Wimmer, Barbara van Loon, Alessandra Amoroso, Chiara Mondello, Cristina Belgiovine, Elena Ferrari, Giada A Locatelli, Giuseppe Villani, Ulrich Hübscher Proceedings of the National Academy of Sciences of the United States of America 2008 pols set
Uracil recognition in archaeal DNA polymerases captured by X-ray crystallography. Susan J Firbank, Josephine Wardle, Pauline Heslop, Richard J Lewis, Bernard A Connolly Journal of molecular biology 2008 topics set
Structure and function of 2:1 DNA polymerase.DNA complexes. Kuo-Hsiang Tang, Ming-Daw Tsai J Cell Physiol 2008 new
Formation of purine-purine mispairs by Sulfolobus solfataricus DNA polymerase IV. Lindsey DeCarlo, A S Prakasha Gowda, Zucai Suo, Thomas E Spratt Biochemistry 2008 topics set
Lesion processing: high-fidelity versus lesion-bypass DNA polymerases. Suse Broyde, Liming Wang, Olga Rechkoblit, Nicholas E Geacintov, Dinshaw J Patel Trends in biochemical sciences 2008 topics set
Protein-template-directed synthesis across an acrolein-derived DNA adduct by yeast Rev1 DNA polymerase. Deepak T Nair, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Structure (London, England : 1993) 2008 new
Specific up-regulation of DNA polymerase by human papillomavirus 16. Song-Nian Liu, Wu-Yun Bai, Russell M Frye, Lin Hou, Bo Zhang Chin Med Sci J 2008 new
Atrial fibrillation: an unusual cause. H J Siebelink, Tineke P Willems, M J W Götte Neth Heart J 2008 new
Phosphorylation of the C subunit (p66) of human DNA polymerase delta. Laure Lemmens, Serge Urbach, Renaud Prudent, Claude Cochet, Giuseppe Baldacci, Patrick Hughes Biochem Biophys Res Commun 2008 pols set
DNA-dependent DNA polymerases. R B Kucera, NM Nichols Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2008 complete Rebecca Kucera*
Historical perspective: Arthur Kornberg, a giant of 20th century biochemistry. IRobert Lehman Trends in biochemical sciences 2008 new
Alpha,beta-methylene-2'-deoxynucleoside 5'-triphosphates as noncleavable substrates for DNA polymerases: isolation, characterization, and stability studies of novel 2'-deoxycyclonucleosides, 3,5'-cyclo-dG, and 2,5'-cyclo-dT. Fengting Liang, Nidhi Jain, Troy Hutchens, David D Shock, William A Beard, Samuel H Wilson, M Paul Chiarelli, Bongsup P Cho J Med Chem 2008 topics set
Ubiquitylation of proliferating cell nuclear antigen and recruitment of human DNA polymerase eta. Nana Nikolaishvili-Feinberg, G Scott Jenkins, Kathleen R Nevis, Dean P Staus, Cameron O Scarlett, Keziban Unsal-Kaçmaz, William K Kaufmann, Marila Cordeiro-Stone Biochemistry 2008 partial results
Peptide ligands specific to the oxidized form of Escherichia coli thioredoxin. Michael D Scholle, Bridget S Banach, Samir M Hamdan, Charles C Richardson, Brian K Kay Biochimica et biophysica acta 2008 pols set
Nuclear import of HSV-1 DNA polymerase processivity factor UL42 is mediated by a C-terminally located bipartite nuclear localization signal. Gualtiero Alvisi, Simone Avanzi, Daniele Musiani, Daria Camozzi, Valerio Leoni, Jennifer D Ly-Huynh, Alessandro Ripalti Biochemistry 2008 topics set
[Effects of human telomerase reverse transcriptase promoter and survivin promoter in targeted tumor gene therapy]. Yongqing Zhang, Hong Ma, Shi-Lian Liu, Yan-Xin Liu, De-Xian Zheng Zhonghua yi xue za zhi 2008 new
Regulation of polymerase exchange between Poleta and Poldelta by monoubiquitination of PCNA and the movement of DNA polymerase holoenzyme. Zhihao Zhuang, Robert E Johnson, Lajos Haracska, Louise Prakash, Satya Prakash, Stephen J Benkovic Proceedings of the National Academy of Sciences of the United States of America 2008 new
Mismatched dNTP incorporation by DNA polymerase beta does not proceed via globally different conformational pathways. Kuo-Hsiang Tang, Marc Niebuhr, Chang-Shung Tung, Hsiu-Chien Chan, Chia-Cheng Chou, Ming-Daw Tsai Nucleic acids research 2008 topics set
Varied active-site constraints in the klenow fragment of E. coli DNA polymerase I and the lesion-bypass Dbh DNA polymerase. Janina Cramer, Gopinath Rangam, Andreas Marx, Tobias Restle Chembiochem 2008 pols set
Production of the soluble form of KIT, s-KIT, abolishes stem cell factor-induced melanogenesis in human melanocytes. Shinya Kasamatsu, Akira Hachiya, Kazuhiko Higuchi, Atsushi Ohuchi, Takashi Kitahara, Raymond E Boissy J Invest Dermatol 2008 new
A high-throughput and single-tube recombination of crude PCR products using a DNA polymerase inhibitor and type IIS restriction enzyme. Ippei Kotera, Takeharu Nagai J Biotechnol 2008 new
Inhibitory effects of cholesterol derivatives on DNA polymerase and topoisomerase activities, and human cancer cell growth. Chisato Ishimaru, Yuko Yonezawa, Isoko Kuriyama, Masayuki Nishida, Hiromi Yoshida, Yoshiyuki Mizushina Lipids 2008 new
Phage phi29 protein p56 prevents viral DNA replication impairment caused by uracil excision activity of uracil-DNA glycosylase. Gemma Serrano-Heras, Alicia Bravo, Margarita Salas Proceedings of the National Academy of Sciences of the United States of America 2008 pols set
Human DNA polymerase iota protects cells against oxidative stress. Tirzah Braz Petta, Satoshi Nakajima, Anastasia Zlatanou, Emmanuelle Despras, Sophie Couve-Privat, Alexander Ishchenko, Alain Sarasin, Akira Yasui, Patricia L Kannouche The EMBO journal 2008 pols set
Determinants of coronary microvascular dysfunction in symptomatic hypertrophic cardiomyopathy. Paul Knaapen, Tjeerd Germans, Paolo G Camici, Ornella E Rimoldi, Folkert J ten Cate, Jurrien M ten Berg, Pieter A Dijkmans, Ronald Boellaard, Willem G van Dockum, Marco J W Götte, Jos W R Twisk, Albert C van Rossum, Adriaan A Lammertsma, Frans C Visser Am J Physiol Heart Circ Physiol 2008 new
2'-deoxy-4'-C-ethynyl-2-halo-adenosines active against drug-resistant human immunodeficiency virus type 1 variants. Atsushi Kawamoto, Eiichi N Kodama, Stefan G Sarafianos, Yasuko Sakagami, Satoru Kohgo, Kenji Kitano, Noriyuki Ashida, Yuko Iwai, Hiroyuki Hayakawa, Hirotomo Nakata, Hiroyuki Mitsuya, Edward Arnold, Masao Matsuoka The international journal of biochemistry & cell biology 2008 pols set
The specific inhibitory effect of demethoxydehydroaltenusin, a derivative of dehydroaltenusin, on mammalian DNA polymerase alpha. Isoko Kuriyama, Keishi Fukudome, Shinji Kamisuki, Kouji Kuramochi, Kazunori Tsubaki, Kengo Sakaguchi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Int J Mol Med 2008 pols set
[Proliferative capacity of mesenchymal stem cells from human fetal bone marrow and their ability to differentiate into the derivative cell types of three embryonic germ layers]. Yue-Chun Wang, Yongqing Zhang Sheng li xue bao : [Acta physiologica Sinica] 2008 new
DNA polymerase beta-catalyzed-PCNA independent long patch base excision repair synthesis: a mechanism for repair of oxidatively damaged DNA ends in post-mitotic brain. Wei Wei, Ella W Englander J Neurochem 2008 new
Long patch base excision repair in mammalian mitochondrial genomes. Bartosz Szczesny, Anne W Tann, Matthew J Longley, William C Copeland, Sankar Mitra The Journal of biological chemistry 2008 complete Bartosz Szczesny*
The solution structure of the amino-terminal domain of human DNA polymerase epsilon subunit B is homologous to C-domains of AAA+ proteins. Tarmo Nuutinen, Helena Tossavainen, Kai Fredriksson, Päivi Pirilä, Perttu Permi, Helmut Pospiech, Juhani E Syvaoja Nucleic acids research 2008 topics set
Hyper-phosphorylated retinoblastoma protein suppresses telomere elongation. Masaharu Takemura, Kazuto Sugimura, Katsuzumi Okumura, Siripan Limsirichaikul, Motoshi Suzuki, Yoshiji Yamada, Shonen Yoshida Bioscience, biotechnology, and biochemistry 2008 new
A single-molecule nanopore device detects DNA polymerase activity with single-nucleotide resolution. Scott L Cockroft, John Chu, Manuel Amorin, M Reza Ghadiri Journal of the American Chemical Society 2008 new
Role of DNA polymerases eta, iota and zeta in UV resistance and UV-induced mutagenesis in a human cell line. Quentin Gueranger, Anne Stary, Saïd Aoufouchi, Ahmad Faili, Alain Sarasin, Claude-Agnès Reynaud, Jean-Claude Weill DNA repair 2008 topics set
A DNA polymerase alpha accessory protein, Mcl1, is required for propagation of centromere structures in fission yeast. Toyoaki Natsume, Yasuhiro Tsutsui, Takashi Sutani, Elaine M Dunleavy, Alison L Pidoux, Hiroshi Iwasaki, Katsuhiko Shirahige, Robin C Allshire, Fumiaki Yamao PloS one 2008 new
Investigation of the alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors as potential cAMP phosphodiesterase-4B2 inhibitors. Matthew D Cullen, York-Fong Cheung, Miles D Houslay, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman Bioorganic & medicinal chemistry letters 2008 pols set
Synthesis and biological evaluation of novel 6-substituted 5-alkyl-2-(arylcarbonylmethylthio)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. Yue-Ping Wang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Bioorganic & medicinal chemistry 2008 pols set
Recent patents of gene sequences relative to DNA polymerases. Linda J Reha-Krantz Recent Pat DNA Gene Seq 2008 complete
Proofreading activity of DNA polymerase Pol2 mediates 3'-end processing during nonhomologous end joining in yeast. Shun-Fu Tseng, Abram Gabriel, Shu-Chun Teng PLoS Genet 2008 complete Shu-Chun Teng*
Non-nucleoside HIV-1 reverse-transcriptase inhibitors. Part 10. Synthesis and anti-HIV activity of 5-alkyl-6-(1-naphthylmethyl)pyrimidin-4(3H)-ones with a mono- or disubstituted 2-amino function as novel 'dihydro-alkoxy-benzyl-oxopyrimidine' (DABO) analogues. Yueping Wang, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque Chemistry & biodiversity 2008 pols set
Replication bypass of the acrolein-mediated deoxyguanine DNA-peptide cross-links by DNA polymerases of the DinB family. Irina G Minko, Kinrin Yamanaka, Ivan D Kozekov, Albena Kozekova, Chiara Indiani, Michael E O'Donnell, Qingfei Jiang, Myron F Goodman, Carmelo J Rizzo, R Stephen Lloyd Chemical research in toxicology 2008 new
Unique substrate spectrum and PCR application of Nanoarchaeum equitans family B DNA polymerase. Jeong Jin Choi, Jae-Geun Song, Ki Hoon Nam, Jong Il Lee, Heejin Bae, Gun A Kim, Younguk Sun, Suk-Tae Kwon Appl Environ Microbiol 2008 new
Entecavir for treatment of hepatitis B virus displays no in vitro mitochondrial toxicity or DNA polymerase gamma inhibition. Charles E Mazzucco, Robert K Hamatake, Richard J Colonno, Daniel J Tenney Antimicrob Agents Chemother 2008 new
Importance of hydrogen bonding for efficiency and specificity of the human mitochondrial DNA polymerase. Harold R Lee, Sandra A Helquist, Eric T Kool, Kenneth A Johnson The Journal of biological chemistry 2008 topics set
Mismatched and matched dNTP incorporation by DNA polymerase beta proceed via analogous kinetic pathways. Michelle P Roettger, Marina Bakhtina, Ming-Daw Tsai Biochemistry 2008 partial results
Epstein-Barr virus-encoded microRNA miR-BART2 down-regulates the viral DNA polymerase BALF5. Stephanie Barth, Thorsten Pfuhl, Alfredo Mamiani, Claudia Ehses, Klaus Roemer, Elisabeth Kremmer, Christoph Jäker, Julia Höck, Gunter Meister, Friedrich A Grässer Nucleic acids research 2008 new
Depletion of mitochondrial DNA in fibroblast cultures from patients with POLG1 mutations is a consequence of catalytic mutations. Neil Ashley, Anthony O'Rourke, Conrad Smith, Susan Adams, Vasantha Gowda, Massimo Zeviani, Garry K Brown, Carl Fratter, Joanna Poulton Human molecular genetics 2008 pols set
Base pair hydrogen bonds are essential for proofreading selectivity by the human mitochondrial DNA polymerase. Harold R Lee, Sandra A Helquist, Eric T Kool, Kenneth A Johnson The Journal of biological chemistry 2008 new
Structure of the DNA repair helicase hel308 reveals DNA binding and autoinhibitory domains. Jodi D Richards, Kenneth A Johnson, Huanting Liu, Anne-Marie McRobbie, Stephen McMahon, Muse Oke, Lester Carter, James H Naismith, Malcolm F White The Journal of biological chemistry 2008 new
Initial crystallographic study of human PCNA in complex with a peptide containing the noncanonical PIP-box sequence of human DNA polymerase iota. Asami Hishiki, Toshiyuki Shimizu, Tomo Hanafusa, Haruo Ohmori, Mamoru Sato, Hiroshi Hashimoto Acta Crystallogr Sect F Struct Biol Cryst Commun 2008 pols set
Protein phosphatase-1 is targeted to DNA polymerase delta via an interaction with the p68 subunit. Yan Gao, Yanjiao Zhou, Bin Xie, Sufang Zhang, Amal A Rahmeh, Hua-Shan Huang, Marietta Y W T Lee, Ernest Y C Lee Biochemistry 2008 pols set
Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase lambda. Katarzyna Bebenek, Miguel Garcia-Diaz, Meredith C Foley, Lars C Pedersen, Tamar Schlick, Thomas A Kunkel EMBO Rep 2008 topics set
Rice exonuclease-1 homologue, OsEXO1, that interacts with DNA polymerase lambda and RPA subunit proteins, is involved in cell proliferation. Tomoyuki Furukawa, Tomohiro Imamura, Hiroko K Kitamoto, Hiroaki Shimada Plant Mol Biol 2008 new
[Effect of nanosize delivery system for ASODN against hTERT on the expression of telomerase in the esophageal cancer EC9706 cells]. Jin Wang, Zhen-zhong Zhang, Tian-yang Zhou, Yu-qiong Liu, Hui-xiang Li Zhonghua zhong liu za zhi [Chinese journal of oncology] 2008 new
Structure of a sliding clamp on DNA. Roxana E Georgescu, Seung-Sup Kim, Olga Yurieva, John Kuriyan, Xiang-Peng Kong, Mike E O'Donnell Cell 2008 topics set
Homozygous W748S mutation in the POLG1 gene in patients with juvenile-onset Alpers syndrome and status epilepticus. Johanna Uusimaa, Reetta Hinttala, Heikki Rantala, Markku Päivärinta, Riitta Herva, Matias Röyttä, Heidi Soini, Jukka S Moilanen, Anne M Remes, Ilmo E Hassinen, Kari Majamaa Epilepsia 2008 pols set
Insertion of dNTPs opposite the 1,N2-propanodeoxyguanosine adduct by Sulfolobus solfataricus P2 DNA polymerase IV. Yazhen Wang, Sarah K Musser, Sam Saleh, Lawrence J Marnett, Martin Egli, Michael P Stone Biochemistry 2008 topics set
DNA polymerase gamma inhibition by vitamin K3 induces mitochondria-mediated cytotoxicity in human cancer cells. Ryohei Sasaki, Yoko Suzuki, Yuko Yonezawa, Yosuke Ota, Yoshiaki Okamoto, Yusuke Demizu, Peng Huang, Hiromi Yoshida, Kazuro Sugimura, Yoshiyuki Mizushina Cancer Sci 2008 new
Xeroderma pigmentosum-variant patients from America, Europe, and Asia. Hiroki Inui, Kyu-Seon Oh, Carine Nadem, Takahiro Ueda, Sikandar G Khan, Ahmet Metin, Engin Gozukara, Steffen Emmert, Hanoch Slor, David B Busch, Carl C Baker, John J DiGiovanna, Deborah Tamura, Cornelia S Seitz, Alexei Gratchev, Wen Hao Wu, Kee Yang Chung, Hye Jin Chung, Esther Azizi, Roger Woodgate, Thomas D Schneider, Kenneth H Kraemer The Journal of investigative dermatology 2008 new
Flexibility of eukaryotic Okazaki fragment maturation through regulated strand displacement synthesis. Carrie M W Stith, Joan F Sterling, Michael A Resnick, Dmitry A Gordenin, Peter M J Burgers The Journal of biological chemistry 2008 new
Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase gamma replication fidelity. Zachary F Pursell, J Tyson McDonald, Christopher K Mathews, Thomas A Kunkel Nucleic acids research 2008 new
Anti-tumor effect of orally administered spinach glycolipid fraction on implanted cancer cells, colon-26, in mice. Naoki Maeda, Yasuo Kokai, Seiji Ohtani, Hiroeki Sahara, Yuko Kumamoto-Yonezawa, Isoko Kuriyama, Takahiko Hada, Noriyuki Sato, Hiromi Yoshida, Yoshiyuki Mizushina Lipids 2008 new
High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: strategic flexibility explains potency against resistance mutations. Kalyan Das, Joseph David Bauman, Arthur D Clark, Yulia Volovik Frenkel, Paul J Lewi, Aaron J Shatkin, Stephen H Hughes, Edward Arnold Proceedings of the National Academy of Sciences of the United States of America 2008 partial results
Dividing the workload at a eukaryotic replication fork. Thomas A Kunkel, Peter M J Burgers Trends Cell Biol 2008 new
Significance of stereochemistry of 3'-terminal phosphorothioate-modified primer in DNA polymerase-mediated chain extension. Barbara Nawrot, Natasha Paul, Beata Rebowska, Wojciech J Stec Mol Biotechnol 2008 new
Inhibitors of DNA polymerase beta: activity and mechanism. Zhijie Gao, David J Maloney, Larisa M Dedkova, Sidney M Hecht Bioorg Med Chem 2008 new
Transmission networks of drug resistance acquired in primary/early stage HIV infection. Bluma G Brenner, Michel Roger, Daniela D Moisi, Maureen Oliveira, Isabelle Hardy, Reuven Turgel, Hugues Charest, Jean-Pierre Routy, Mark A. Wainberg AIDS (London, England) 2008 pols set
Inhibitory effects of vitamin K3 on DNA polymerase and angiogenesis. Kiminori Matsubara, Tomoko Kayashima, Masaharu Mori, Hiromi Yoshida, Yoshiyuki Mizushina Int J Mol Med 2008 new
Evolution of DNA polymerase iota structure and function in eukaryotes. Alena V Makarova, Vyacheslav Z Tarantul, Leonid V Gening Biochemistry (Mosc) 2008 new
The proofreading exonuclease subunit epsilon of Escherichia coli DNA polymerase III is tethered to the polymerase subunit alpha via a flexible linker. Kiyoshi Ozawa, Slobodan Jergic, Ah Young Park, Nicholas E Dixon, Gottfried Otting Nucleic acids research 2008 pols set
Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues. Andrea Lisco, Christophe Vanpouille, Egor P Tchesnokov, Jean-Charles Grivel, Angélique Biancotto, Beda Brichacek, Julie Elliott, Emilie Fromentin, Robin Shattock, Peter Anton, Robert Gorelick, Jan Balzarini, Christopher McGuigan, Marco Derudas, Matthias Götte, Raymond F Schinazi, Leonid Margolis Cell Host Microbe 2008 partial results
DNA polymerases beta and lambda as potential participants of TLS during genomic DNA replication on the lagging strand. A A Shtygasheva, Ekaterina A Belousova, Nadejda I Rechkunova, Natalia A Lebedeva, Olga I Lavrik Biochemistry. Biokhimii͡a 2008 new
Interactions of Escherichia coli thioredoxin, the processivity factor, with bacteriophage T7 DNA polymerase and helicase. Sharmistha Ghosh, Samir M Hamdan, Timothy E Cook, Charles C Richardson The Journal of biological chemistry 2008 pols set
Interaction of APE1 and other repair proteins with DNA duplexes imitating intermediates of DNA repair and replication. Nadezhda S Dyrkheeva, Svetlana N Khodyreva, Olga I Lavrik Biochemistry. Biokhimii͡a 2008 new
Cell cycle phase dependent role of DNA polymerase beta in DNA repair and survival after ionizing radiation. Christie Vermeulen, Manon Verwijs-Janssen, Adrian C Begg, Conchita Vens Radiother Oncol 2008 new
The Leu22Pro tumor-associated variant of DNA polymerase beta is dRP lyase deficient. Shibani Dalal, Anna K Chikova, Joachim Jaeger, Joann B Sweasy Nucleic acids research 2008 new
4"-Benzoylureido-TSAO derivatives as potent and selective non-nucleoside HCMV inhibitors. Structure-activity relationship and mechanism of antiviral action. Sonia de Castro, M Teresa Peromingo, Lieve Naesens, Graciela Andrei, Robert Snoeck, Jan Balzarini, Sonsoles Velázquez, María-José Camarasa Journal of medicinal chemistry 2008 new
New DNA polymerase from the hyperthermophilic marine archaeon Thermococcus thioreducens. Damien Marsic, Jean-Michel Flaman, Joseph D Ng Extremophiles 2008 new
RAD18 signals DNA polymerase IOTA to stalled replication forks in cells entering S-phase with DNA damage. Shelly Kakar, Nicholas B Watson, William Glenn McGregor Adv Exp Med Biol 2008 new
Hopping of a processivity factor on DNA revealed by single-molecule assays of diffusion. Gloria Komazin-Meredith, Rossen Mirchev, David E Golan, Antoine M van Oijen, Donald M Coen Proceedings of the National Academy of Sciences of the United States of America 2008 new
The positively charged surface of herpes simplex virus UL42 mediates DNA binding. Gloria Komazin-Meredith, Webster L Santos, David J Filman, James M Hogle, Gregory L Verdine, Donald M Coen The Journal of biological chemistry 2008 new
Discovery of 3-{5-[(6-amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5 -chlorobenzonitrile (MK-4965): a potent, orally bioavailable HIV-1 non-nucleoside reverse transcriptase inhibitor with improved potency against key mutant viruses. Thomas J Tucker, John T Sisko, Robert M Tynebor, Theresa M Williams, Peter J Felock, Jessica A Flynn, Ming-Tain Lai, Yuexia Liang, Georgia B McGaughey, Meiquing Liu, Michael D Miller, Gregory Moyer, Vandna Munshi, Rebecca A Perlow-Poehnelt, Sridhar Prasad, John C Reid, Rosa Sanchez, Maricel Torrent, Joseph P Vacca, Bang-Lin Wan, Youwei Yan J Med Chem 2008 partial results
A method to assay inhibitors of DNA polymerase IIIC activity. Michelle M Butler, George E Wright Methods Mol Med 2008 new
Kinetic analysis of translesion synthesis opposite bulky N2- and O6-alkylguanine DNA adducts by human DNA polymerase REV1. Jeong-Yun Choi, F Peter Guengerich The Journal of biological chemistry 2008 pols set
Inhibition of translation by a short element in the 5' leader of the herpes simplex virus 1 DNA polymerase transcript. Kevin F Bryant, Donald M Coen Journal of virology 2008 new
Crystal structures of HIV-1 reverse transcriptase complexes with thiocarbamate non-nucleoside inhibitors. Andrea Spallarossa, Sara Cesarini, Angelo Ranise, Marco Ponassi, Torsten Unge, Martino Bolognesi Biochem Biophys Res Commun 2008 partial results
Inhibitors of HIV-1 reverse transcriptase. Tatiana Ilina, Michael A. Parniak Advances in pharmacology (San Diego, Calif.) 2008 pols set
Initiation of DNA replication by a third parallel DNA strand bound in a triple-helix manner leads to strand invasion. Patrick P Lestienne, François Boudsocq, Jacques E Bonnet Biochemistry 2008 topics set
Mutagenic and recombinagenic responses to defective DNA polymerase delta are facilitated by the Rev1 protein in pol3-t mutants of Saccharomyces cerevisiae. Erica Mito, Janet V Mokhnatkin, Molly C Steele, Victoria L Buettner, Steve S Sommer, Glenn M Manthey, Adam M Bailis Genetics 2008 topics set
Design of annulated pyrazoles as inhibitors of HIV-1 reverse transcriptase. Zachary K Sweeney, Seth F Harris, Seth F Arora, Hassan Javanbakht, Yingqian Li, Jennifer Fretland, James P Davidson, J Roland Billedeau, Shelley K Gleason, Donald R Hirschfeld, Joshua J Kennedy-Smith, Taraneh Mirzadegan, Ralf Roetz, Mark Smith, Sarah Sperry, Judy M Suh, Jeffrey Wu, Stan Tsing, Armando G Villaseñor, Amber Paul, Guoping Su, Gabrielle M Heilek, Julie Qi Hang, Amy S Zhou, Jesper A Jernelius, Fang-Jie Zhang, Klaus Klumpp J Med Chem 2008 partial results
Partial reconstitution of DNA large loop repair with purified proteins from Saccharomyces cerevisiae. Debbie Sommer, Carrie M W Stith, Peter M J Burgers, Robert S Lahue Nucleic acids research 2008 new
Phage phi29 and Nf terminal protein-priming domain specifies the internal template nucleotide to initiate DNA replication. Elisa Longás, Laurentino Villar, José María Lázaro, Miguel de Vega, Margarita Salas Proceedings of the National Academy of Sciences of the United States of America 2008 topics set
DNA polymerase kappa produces interrupted mutations and displays polar pausing within mononucleotide microsatellite sequences. Suzanne E Hile, Kristin A Eckert Nucleic acids research 2008 new
On the inhibitory affect of some dementia drugs on DNA polymerase Beta activity. V N Vyjayanti, N S Chary, Kalluri Subba Rao Neurochem Res 2008 new
Efficient inhibition of human cytomegalovirus DNA polymerase expression by small hairpin RNA in vitro. Ran Tao, Miaofeng Hu, Qunjun Duan, Shiqiang Shang Curr Microbiol 2008 pols set
Selective targeting of the HIV-1 reverse transcriptase catalytic complex through interaction with the "primer grip" region by pyrrolobenzoxazepinone non-nucleoside inhibitors correlates with increased activity towards drug-resistant mutants. Samantha Zanoli, Sandra Gemma, Stefania Butini, Margherita Brindisi, Bhupendra P Joshi, Giuseppe Campiani, Caterina Fattorusso, Marco Persico, Emmanuele Crespan, Reynel Cancio, Silvio Spadari, Ulrich Hübscher, Giovanni Maga Biochemical pharmacology 2008 pols set
Determination of DNA polymerase and nuclease activities of DNA-dependent polymerases using fluorescence detection under real-time conditions. A G Bragin, S A Glushkov, M K Ivanov, A A Krasnov, G M Dymshits Biochemistry (Mosc) 2008 new
Roles of PCNA-binding and ubiquitin-binding domains in human DNA polymerase eta in translesion DNA synthesis. Narottam Acharya, Jung-Hoon Yoon, Himabindu Gali, Ildiko Unk, Lajos Haracska, Robert E Johnson, Jerard Hurwitz, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2008 pols set
Assessment of global left ventricular functional parameters: analysis of every second short-axis Magnetic Resonance Imaging slices is as accurate as analysis of consecutive slices. Daniel D Lubbers, Tineke P Willems, Pieter A van der Vleuten, Jelle Overbosch, Marco J W Götte, Dirk J van Veldhuisen, Matthijs Oudkerk Int J Cardiovasc Imaging 2008 new
Inhibition of human immunodeficiency virus type 1 replication in human cells by Debio-025, a novel cyclophilin binding agent. Roger G Ptak, Philippe A Gallay, Dirk Jochmans, Andrew P Halestrap, Urs T Ruegg, Luke A Pallansch, Michael D Bobardt, Marie-Pierre P De Béthune, Johan Neyts, Erik De Clercq, Jean-Maurice Dumont, Pietro Scalfaro, Kamel Besseghir, Roland M Wenger, Brigitte Rosenwirth Antimicrobial agents and chemotherapy 2008 pols set
Templated mutagenesis in bacteriophage T4 involving imperfect direct or indirect sequence repeats. Gary E Schultz, John W Drake Genetics 2008 complete
DNA conjugation by Staudinger ligation. Samuel H Weisbrod, Anna Baccaro, Andreas Marx Nucleic acids symposium series (2004) 2008 new
Quantum dot FRET biosensors that respond to pH, to proteolytic or nucleolytic cleavage, to DNA synthesis, or to a multiplexing combination. Miho Suzuki, Yuzuru Husimi, Hirokazu Komatsu, Koji Suzuki, Kenneth T Douglas Journal of the American Chemical Society 2008 new
Kinetic analysis of correct nucleotide insertion by a Y-family DNA polymerase reveals conformational changes both prior to and following phosphodiester bond formation as detected by tryptophan fluorescence. Jeff W Beckman, Qixin Wang, F Peter Guengerich The Journal of biological chemistry 2008 partial results
The human cytomegalovirus UL44 C clamp wraps around DNA. Gloria Komazin-Meredith, Robert J Petrella, Webster L Santos, David J Filman, James M Hogle, Gregory L Verdine, Martin Karplus, Donald M Coen Structure (London, England : 1993) 2008 pols set
Interventricular mechanical asynchrony in pulmonary arterial hypertension: left-to-right delay in peak shortening is related to right ventricular overload and left ventricular underfilling. J Tim Marcus, C Tji-Joong Gan, Jaco J M Zwanenburg, Anco Boonstra, Cor P Allaart, Marco J W Götte, Anton Vonk-Noordegraaf J Am Coll Cardiol 2008 new
The bacteriophage phi29 DNA polymerase. Margarita Salas, Luis Blanco, José María Lázaro, Miguel de Vega IUBMB Life 2008 pols set
Role of homodimerization of human cytomegalovirus DNA polymerase accessory protein UL44 in origin-dependent DNA replication in cells. Elisa Sinigalia, Gualtiero Alvisi, Beatrice Mercorelli, Donald M Coen, Gregory S Pari, David A Jans, Alessandro Ripalti, Giorgio Palù, Arianna Loregian Journal of virology 2008 pols set
Examining the ribonuclease H primer grip of HIV-1 reverse transcriptase by charge neutralization of RNA/DNA hybrids. Chandravanu Dash, Brian J Scarth, Christopher Badorrek, Matthias Götte, Stuart F J Le Grice Nucleic acids research 2008 pols set
Regulated proteolysis of DNA polymerase eta during the DNA-damage response in C. elegans. Seung-Hwan Kim, W Matthew Michael Molecular cell 2008 new
1,2,3-Thiadiazole thioacetanilides as a novel class of potent HIV-1 non-nucleoside reverse transcriptase inhibitors. Peng Zhan, Xinyong Liu, Yuan Cao, Yan Wang, Christophe Pannecouque, Erik De Clercq Bioorganic & medicinal chemistry letters 2008 pols set
Novel strategies for the site-specific covalent labelling of nucleic acids. Samuel H Weisbrod, Andreas Marx Chemical communications (Cambridge, England) 2008 new
Dpb2p, a noncatalytic subunit of DNA polymerase epsilon, contributes to the fidelity of DNA replication in Saccharomyces cerevisiae. Malgorzata Jaszczur, Krzysztof Flis, Justyna Rudzka, Joanna Kraszewska, Martin E Budd, Piotr Polaczek, Judith L Campbell, Piotr Jonczyk, I Fijalkowska Genetics 2008 pols set
Activity of the small modified amino acid alpha-hydroxy glycineamide on in vitro and in vivo human immunodeficiency virus type 1 capsid assembly and infectivity. Samir Abdurahman, Akos Végvári, Masoud Youssefi, Michael Levi, Stefan Höglund, Elin Andersson, Peter Horal, Bo Svennerholm, Jan Balzarini, Anders Vahlne Antimicrobial agents and chemotherapy 2008 pols set
Rapid purification of truncated Taq DNA polymerase Stoffel fragment by boiling lysis of bacterial expression cultures. Zhengan Yang, Yumei Ding, Yongqing Zhang, Feihu Liu Biotechnol Appl Biochem 2008 pols set
hTERT-targeted RNA interference inhibits tumorigenicity and motility of HCT116 cells. Ying Shen, Yong-Wei Zhang, Zhi-Xiang Zhang, Ze-Hong Miao, Jian Ding Cancer biology & therapy 2008 new
The epsilon subunit of DNA polymerase III Is involved in the nalidixic acid-induced SOS response in Escherichia coli. Jennifer Reineke Pohlhaus, David T Long, Erin O'Reilly, Kenneth N Kreuzer J Bacteriol 2008 complete Kenneth N Kreuzer*
Whole genome amplification with Phi29 DNA polymerase to enable genetic or genomic analysis of samples of low DNA yield. Kaisa Silander, Janna Saarela Methods in molecular biology (Clifton, N.J.) 2008 pols set
Pyranicin, a non-classical annonaceous acetogenin, is a potent inhibitor of DNA polymerase, topoisomerase and human cancer cell growth. Shunya Takahashi, Yuko Yonezawa, Akemi Kubota, Narihito Ogawa, Katsuya Maeda, Hiroyuki Koshino, Tadashi Nakata, Hiromi Yoshida, Yoshiyuki Mizushina Int J Oncol 2008 new
DNA polymerase bypass in vitro and in E. coli of a C-nucleotide analogue of Fapy-dG. Yvonne N Weledji, Carissa J Wiederholt, Michael O Delaney, Marc M Greenberg Bioorg Med Chem 2008 pols set
Interplay between DNA polymerase and proliferating cell nuclear antigen switches off base excision repair of uracil and hypoxanthine during replication in archaea. Kieran Emptage, Rory O'Neill, Alexandra Solovyova, Bernard A Connolly Journal of molecular biology 2008 new
Novel azaphilones, kasanosins A and B, which are specific inhibitors of eukaryotic DNA polymerases beta and lambda from Talaromyces sp. Takuma Kimura, Masayuki Nishida, Kouji Kuramochi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Bioorganic & medicinal chemistry 2008 pols set
Non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 11: structural modulations of diaryltriazines with potent anti-HIV activity. Yuan-Zhen Xiong, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque European journal of medicinal chemistry 2008 pols set
Effect of oxidatively damaged DNA on the active site preorganization during nucleotide incorporation in a high fidelity polymerase from Bacillus stearothermophilus. Ravindra Venkatramani, Ravi Radhakrishnan Proteins 2008 topics set
Exploring the role of large conformational changes in the fidelity of DNA polymerase beta. Yun Xiang, Myron F Goodman, William A Beard, Samuel H Wilson, Arieh Warshel Proteins 2008 new
DNA polymerase I is not required for replication of linear chromosomes in streptomyces. Tzu-Wen Huang, Carton W Chen J Bacteriol 2008 new
DNA polymerase eta is a limiting factor for A:T mutations in Ig genes and contributes to antibody affinity maturation. Keiji Masuda, Rika Ouchida, Masayuki Yokoi, Fumio Hanaoka, Takachika Azuma, Ji-Yang Wang Eur J Immunol 2008 new
AKAP149 binds to HIV-1 reverse transcriptase and is involved in the reverse transcription. Julie Lemay, Priscilla Maidou-Peindara, Reynel Cancio, Eric Ennifar, Gaël Coadou, Giovanni Maga, Jean-Christophe Rain, Richard Benarous, Lang Xia Liu Journal of molecular biology 2008 pols set
Substrate-induced stable enzyme-inhibitor complex formation allows tight binding of novel 2-aminopyrimidin-4(3H)-ones to drug-resistant HIV-1 reverse transcriptase mutants. Alberta Samuele, Marcella Facchini, Dante Rotili, Antonello Mai, Marino Artico, Mercedes Armand-Ugón, José A Esté, Giovanni Maga ChemMedChem 2008 pols set
Structures of DNA polymerase beta with active-site mismatches suggest a transient abasic site intermediate during misincorporation. Vinod K Batra, William A Beard, David D Shock, Lars C Pedersen, Samuel H Wilson Molecular cell 2008 topics set
Sensing domain and extension rate of a family B-type DNA polymerase determine the stalling at a deaminated base. Yun Jae Kim, Sun-Shin Cha, Hyun Sook Lee, Yong Gu Ryu, Seung Seob Bae, Yona Cho, Hyun-Soo Cho, Soon-Jong Kim, Suk-Tae Kwon, Jung-Hyun Lee, Sung Gyun Kang J Microbiol Biotechnol 2008 new
Role for DNA polymerase kappa in the processing of N2-N2-guanine interstrand cross-links. Irina G Minko, Michael B Harbut, Ivan D Kozekov, Albena Kozekova, Petra M Jakobs, Susan B Olson, Robb E Moses, Thomas M Harris, Carmelo J Rizzo, R Stephen Lloyd The Journal of biological chemistry 2008 new
Synthesis of 3'-deoxyapionucleoside triphosphates and their incorporation into DNA by DNA polymerase. Mayumi Kataoka, Kousuke Sato, Akira Matsuda Nucleic Acids Symp Ser (Oxf) 2008 new
A multidisciplinary approach for the identification of novel HIV-1 non-nucleoside reverse transcriptase inhibitors: S-DABOCs and DAVPs. Marco Radi, Chiara Falciani, Lorenzo Contemori, Elena Petricci, Giovanni Maga, Alberta Samuele, Samantha Zanoli, Montserrat Terrazas, Marinunzia Castria, Andrea Togninelli, José A Esté, Imma Clotet-Codina, Mercedes Armand-Ugón, Maurizio Botta ChemMedChem 2008 pols set
Mutagenesis is elevated in male germ cells obtained from DNA polymerase-beta heterozygous mice. Diwi Allen, Damon C Herbert, C Alex McMahan, Vladimir Rotrekl, Robert W Sobol, Samuel H Wilson, Christi A Walter Biol Reprod 2008 new
The T4 phage UvsW protein contains both DNA unwinding and strand annealing activities. Scott W Nelson, Stephen J Benkovic The Journal of biological chemistry 2007 topics set
Exchange of DNA polymerases at the replication fork of bacteriophage T7. Donald E Johnson, Masateru Takahashi, Samir M Hamdan, Seung-Joo Lee, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 2007 topics set
Characterization of promoter regulatory elements involved in downexpression of the DNA polymerase kappa in colorectal cancer. Fanny Lemée, Clarisse Bavoux, Marie-Jeanne Pillaire, Anne Bieth, Carlos Renato Machado, Sérgio Danilo Junho Pena, R Guimbaud, Janick Selves, Jean-Sébastien Hoffmann, Christophe Cazaux Oncogene 2007 new
Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesis. Ranga N Venkatesan, Piper M Treuting, Evan D Fuller, Robert E Goldsby, Thomas H Norwood, Ted A Gooley, Warren C Ladiges, Bradley D Preston, Lawrence A Loeb Molecular and cellular biology 2007 partial results
Crystal structures of clinically relevant Lys103Asn/Tyr181Cys double mutant HIV-1 reverse transcriptase in complexes with ATP and non-nucleoside inhibitor HBY 097. Kalyan Das, Stefan G Sarafianos, Arthur D Clark, Paul L Boyer, Stephen H Hughes, Edward Arnold Journal of molecular biology 2007 partial results
The use of non-natural nucleotides to probe template-independent DNA synthesis. Anthony J Berdis, David McCutcheon Chembiochem 2007 topics set
Interaction of 2'-deoxyguanosine triphosphate analogue inhibitors of HIV reverse transcriptase with human mitochondrial DNA polymerase gamma. Adrian S Ray, Joy Y Feng, Eisuke Murakami, Chung K Chu, Raymond F Schinazi, Karen S Anderson Antivir Chem Chemother 2007 new
Correlation of mitochondrial superoxide dismutase and DNA polymerase beta in mammalian dermal fibroblasts with species maximal lifespan. Melanie F Brown, Jeffrey A Stuart Mech Ageing Dev 2007 topics set
Highly efficient isothermal DNA amplification system using three elements of 5'-DNA-RNA-3' chimeric primers, RNaseH and strand-displacing DNA polymerase. Hiroyuki Mukai, Takashi Uemori, Osamu Takeda, Eiji Kobayashi, Junko Yamamoto, Kazue Nishiwaki, Tatsuji Enoki, Hiroaki Sagawa, Kiyozo Asada, Ikunoshin Kato J Biochem 2007 new
Interactions of the DNA polymerase X of African swine fever virus with double-stranded DNA. Functional structure of the complex. Maria J Jezewska, Paul J Bujalowski, Wlodzimierz Bujalowski Journal of molecular biology 2007 new
The eukaryotic leading and lagging strand DNA polymerases are loaded onto primer-ends via separate mechanisms but have comparable processivity in the presence of PCNA. Olga Chilkova, Peter Stenlund, Isabelle Isoz, Carrie M W Stith, Pawel Grabowski, Else-Britt Lundström, Peter M J Burgers, Erik Johansson Nucleic acids research 2007 pols set
Crystallization and preliminary crystallographic study of DNA polymerase from Pyrococcus furiosus. Hirokazu Nishida, Maiko Tanabe, Yoshizumi Ishino, Takuji Oyama, Kosuke Morikawa Protein Pept Lett 2007 pols set
Predicting HIV coreceptor usage on the basis of genetic and clinical covariates. Tobias Sing, Andrew J Low, Niko Beerenwinkel, Oliver Sander, Peter K Cheung, Francisco S Domingues, Joachim Büch, Martin Däumer, Rolf Kaiser, Thomas Lengauer, P Richard Harrigan Antivir Ther 2007 new
Enzymatic incorporation of LNA nucleotides into DNA strands. Rakesh N Veedu, Birte Vester, Jesper Wengel Chembiochem : a European journal of chemical biology 2007 topics set
Mutations in the connection domain of HIV-1 reverse transcriptase increase 3'-azido-3'-deoxythymidine resistance. Galina N Nikolenko, Krista A Delviks-Frankenberry, Sarah Palmer, Frank Maldarelli, Matthew J Fivash, John M Coffin, Vinay K Pathak Proceedings of the National Academy of Sciences of the United States of America 2007 topics set
Structure and activity of Y-class DNA polymerase DPO4 from Sulfolobus solfataricus with templates containing the hydrophobic thymine analog 2,4-difluorotoluene. Adriana Irimia, Robert Lawton Eoff, Pradeep S Pallan, F Peter Guengerich, Martin Egli The Journal of biological chemistry 2007 topics set
Molecular basis of selectivity of nucleoside triphosphate incorporation opposite O6-benzylguanine by sulfolobus solfataricus DNA polymerase Dpo4: steady-state and pre-steady-state kinetics and x-ray crystallography of correct and incorrect pairing. Robert Lawton Eoff, Karen C Angel, Martin Egli, F Peter Guengerich The Journal of biological chemistry 2007 partial results
Overexpression of DNA polymerase beta results in an increased rate of frameshift mutations during base excision repair. Katie Chan, Sue Houlbrook, Qiu-Mei Zhang, Mark Harrison, Ian D Hickson, Grigory L Dianov Mutagenesis 2007 new
Multiple molecular markers as predictors of colorectal cancer in patients with normal perioperative serum carcinoembryonic antigen levels. Jaw-Yuan Wang, Shiu-Ru Lin, Deng-Chyang Wu, Chien-Yu Lu, Fang-Jung Yu, Jan-Sing Hsieh, Tian-Lu Cheng, Lok-Beng Koay, Yih-Huei Uen Clinical cancer research : an official journal of the American Association for Cancer Research 2007 new
Mcm10 and And-1/CTF4 recruit DNA polymerase alpha to chromatin for initiation of DNA replication. Wenge Zhu, Chinweike Ukomadu, Sudhakar Jha, Takeshi Senga, Suman K Dhar, James A Wohlschlegel, Leta K Nutt, Sally Kornbluth, Anindya Dutta Genes Dev 2007 new
Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases. Andrea J Berman, Satwik Kamtekar, Jessica L Goodman, José María Lázaro, Miguel de Vega, Luis Blanco, Margarita Salas, Thomas A Steitz The EMBO journal 2007 topics set
The E295K DNA polymerase beta gastric cancer-associated variant interferes with base excision repair and induces cellular transformation. Tieming Lang, Shibani Dalal, Anna K Chikova, Daniel Dimaio, Joann B Sweasy Molecular and cellular biology 2007 topics set
KDR expression is associated with the stage and cigarette smoking of the patients with lung cancer. She-Juan An, Qiang Nie, Zhi-Hong Chen, Qiu-Xiong Lin, Zhengqiang Wang, Zhongwen Xie, Shi-Liang Chen, Ying Huang, Ai-Ye Zhang, Jin-Feng Yan, Hong-Sui Wu, Jia-Ying Lin, Rong Li, Xu-Chao Zhang, Ai-Lin Guo, Tony S Mok, Yi-Long Wu Journal of cancer research and clinical oncology 2007 new
Partial purification and characterization of DNA polymerase beta-like enzyme from Plasmodium falciparum. Prapa Nunthawarasilp, Songsak Petmitr, Porntip Chavalitshewinkoon-Petmitr Mol Biochem Parasitol 2007 new
HIV-1 reverse transcriptase inhibitors. Yazan El Safadi, Valérie Vivet-Boudou, Roland Marquet Appl Microbiol Biotechnol 2007 complete Roland Marquet*
Single-molecule and ensemble fluorescence assays for a functionally important conformational change in T7 DNA polymerase. Guobin Luo, Michael Wang, William H Konigsberg, X Sunney Xie Proceedings of the National Academy of Sciences of the United States of America 2007 pols set
What a difference a decade makes: insights into translesion DNA synthesis. Wei Wen Yang, Roger Woodgate Proceedings of the National Academy of Sciences of the United States of America 2007 topics set
High-level production of a functional recombinant hepatitis B virus polymerase in insect cells with a baculovirus expression system. Xiaoyan Wang, Linlin Gao, Fei Deng, Yongqing Zhang, Yan Li, Jusheng Lin Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2007 new
Increased catalytic activity and altered fidelity of human DNA polymerase iota in the presence of manganese. Ekaterina G Frank, Roger Woodgate The Journal of biological chemistry 2007 pols set
Synthesis, biological activity, and crystal structure of potent nonnucleoside inhibitors of HIV-1 reverse transcriptase that retain activity against mutant forms of the enzyme. Marshall L Morningstar, Thomas Roth, David W Farnsworth, Marilyn B Kroeger Smith, Karen M Watson, Robert W Buckheit, Kalyan Das, Weiming Zhang, Edward Arnold, John G Julias, Stephen H Hughes, Christopher J Michejda Journal of medicinal chemistry 2007 pols set
Unexpected efficient ab initio DNA synthesis at low temperature by using thermophilic DNA polymerase. Xingguo Liang, Tomohiro Kato, Hiroyuki Asanuma Nucleic Acids Symp Ser (Oxf) 2007 new
Bypass of DNA lesions generated during anticancer treatment with cisplatin by DNA polymerase eta. Aaron Alt, Katja Lammens, Claudia Chiocchini, Alfred Lammens, J Carsten Pieck, David Kuch, Karl-Peter Hopfner, Thomas Carell Science 2007 topics set
Following an environmental carcinogen N2-dG adduct through replication: elucidating blockage and bypass in a high-fidelity DNA polymerase. Pingna Xu, Lida Oum, Lorena S Beese, Nicholas E Geacintov, Suse Broyde Nucleic acids research 2007 new
Human influenza A virus (H5N1) detection by a novel multiplex PCR typing method. Shumei Zou, Jian Han, Leying Wen, Yan Liu, Kassi Cronin, Shanjuan H Lum, Lu Gao, Jie Dong, Yongqing Zhang, Yuanji Guo, Yuelong Shu Journal of clinical microbiology 2007 new
Bcl2 impedes DNA mismatch repair by directly regulating the hMSH2-hMSH6 heterodimeric complex. Yongzhong Hou, Fengqin Gao, Qinhong Wang, Jinfeng Zhao, Tammy Flagg, Yongqing Zhang, Xingming Deng The Journal of biological chemistry 2007 new
Mitochondrial DNA polymerase gamma variants in idiopathic sporadic Parkinson disease. Petri T Luoma, J Eerola, Sofia Ahola, Anna H Hakonen, O Hellström, K T Kivistö, P J Tienari, Anu Suomalainen Neurology 2007 pols set
DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination. Xiaoming Wu, Janet Stavnezer J Exp Med 2007 new
Novel non-nucleoside human cytomegalovirus inhibitors based upon TSAO nucleoside derivatives: structure-activity relationships. Sonia de Castro, Graziela Andrei, Robert Snoeck, Jan Balzarini, María-José Camarasa, Sonsoles Velázquez Nucleosides, nucleotides & nucleic acids 2007 pols set
(R)-beta,gamma-fluoromethylene-dGTP-DNA ternary complex with DNA polymerase beta. Charles E McKenna, Boris A Kashemirov, Thomas G Upton, Vinod K Batra, Myron F Goodman, Lars C Pedersen, William A Beard, Samuel H Wilson Journal of the American Chemical Society 2007 topics set
Synthesis and anti-HIV studies of 2-adamantyl-substituted thiazolidin-4-ones. Jan Balzarini, Barbara Orzeszko, Jan K Maurin, Andrzej Orzeszko European journal of medicinal chemistry 2007 pols set
DNA polymerase switching on homotrimeric PCNA at the replication fork of the euryarchaea Pyrococcus abyssi. Christophe Rouillon, Ghislaine Henneke, Didier Flament, Joël Querellou, Jean-Paul Raffin Journal of molecular biology 2007 new
Human Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA damage during replication. Sharbani Chattopadhyay, Anja-Katrin Bielinsky Mol Biol Cell 2007 new
Synthesis and anti-HIV activity of new metabolically stable alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors incorporating N-methoxy imidoyl halide and 1,2,4-oxadiazole systems. Takeshi Sakamoto, Matthew D Cullen, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman Journal of medicinal chemistry 2007 pols set
Comparative evaluation of the activity of antivirals towards feline immunodeficiency virus in different cell culture systems. F J U M van der Meer, N M P Schuurman, Jan Balzarini, H F Egberink Antiviral research 2007 new
The nucleoside analogs 4'C-methyl thymidine and 4'C-ethyl thymidine block DNA synthesis by wild-type HIV-1 RT and excision proficient NRTI resistant RT variants. Paul L Boyer, John G Julias, Zandrea Ambrose, Maqbool A Siddiqui, Victor E Marquez, Stephen H Hughes Journal of molecular biology 2007 topics set
Antiviral activity of 3-(3,5-dimethylbenzyl)uracil derivatives against HIV-1 and HCMV. Tokumi Maruyama, Yosuke Demizu, Shigetada Kozai, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoecks, Graciella Andrei, Erik De Clercq Nucleosides, nucleotides & nucleic acids 2007 pols set
Cloning, expression and characterization of human tissue-specific DNA polymerase lambda2. Fu Gu, Chun You, JianPing Liu, Ao Chen, Yao Yu, Xiang Wang, DaFang Wan, JianRen Gu, HanYing Yuan, Yingqian Li, Hong Lü Sci China C Life Sci 2007 pols set
Synthesis and anti-HIV activity evaluation of 1-[(alkenyl or alkynyl or alkyloxy)methyl]-5-alkyl-6-(1-naphthoyl)-2,4-pyrimidinediones as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. Lei Ji, Fen-Er Chen, Bin Xie, Erik De Clercq, Jan Balzarini, Christophe Pannecouque European journal of medicinal chemistry 2007 pols set
The checkpoint clamp, Rad9-Rad1-Hus1 complex, preferentially stimulates the activity of apurinic/apyrimidinic endonuclease 1 and DNA polymerase beta in long patch base excision repair. Agnieszka Gembka, Magali Toueille, Ekaterina Smirnova, Rainer Poltz, Elena Ferrari, Giuseppe Villani, Ulrich Hübscher Nucleic acids research 2007 new
Anti-tumor effects of the glycolipids fraction from spinach which inhibited DNA polymerase activity. Naoki Maeda, Yasuo Kokai, Seiji Ohtani, Hiroeki Sahara, Takahiko Hada, Chisato Ishimaru, Isoko Kuriyama, Yuko Yonezawa, Hiroshi Iijima, Hiromi Yoshida, Noriyuki Sato, Yoshiyuki Mizushina Nutr Cancer 2007 new
Cloning, purification, and characterization of a new DNA polymerase from a hyperthermophilic archaeon, Thermococcus sp. NA1. Yun Jae Kim, Hyun Sook Lee, Seung Seob Bae, Jeong Ho Jeon, Jae Kyu Lim, Yona Cho, Ki Hoon Nam, Sung Gyun Kang, Soon-Jong Kim, Suk-Tae Kwon, Jung-Hyun Lee J Microbiol Biotechnol 2007 new
A novel interaction between DNA ligase III and DNA polymerase gamma plays an essential role in mitochondrial DNA stability. Ananya De, Colin Campbell Biochem J 2007 new
Nitroimidazoles. V. Synthesis and anti-HIV evaluation of new 5-substituted piperazinyl-4-nitroimidazole derivatives. Yaseen A Al-Soud, Najim A Al-Masoudi, Hamed Gh Hassan, Erik De Clercq, Christophe Pannecouque Acta pharmaceutica (Zagreb, Croatia) 2007 new
The human GINS complex binds to and specifically stimulates human DNA polymerase alpha-primase. Mariarosaria De Falco, Elena Ferrari, Mariarita De Felice, Mosè Rossi, Ulrich Hübscher, Francesca M Pisani EMBO Rep 2007 pols set
Reducing DNA polymerase alpha in the absence of Drosophila ATR leads to P53-dependent apoptosis and developmental defects. Jeannine R LaRocque, Diana L Dougherty, Sumreen K Hussain, Jeff Sekelsky Genetics 2007 new
Characterization of the uracil-DNA glycosylase activity of Epstein-Barr virus BKRF3 and its role in lytic viral DNA replication. Chih-Chung Lu, Ho-Ting Huang, Jiin-Tarng Wang, Geir Slupphaug, Tsai-Kun Li, Meng-Chuan Wu, Yi-Chun Chen, Chung-Pei Lee, Mei-Ru Chen Journal of virology 2007 complete Mei-Ru Chen*
Genotypic analysis of the protease and reverse transcriptase of HIV type 1 isolates from recently infected injecting drug users in western China. Lingjie Liao, Hui Xing, Xincang Li, Yuhua Ruan, Yongqing Zhang, Guangming Qin, Yiming Shao AIDS research and human retroviruses 2007 pols set
Determining human immunodeficiency virus coreceptor use in a clinical setting: degree of correlation between two phenotypic assays and a bioinformatic model. Katharina Skrabal, Andrew J Low, Winnie W Y Dong, Tobias Sing, Peter K Cheung, Fabrizio Mammano, P Richard Harrigan J Clin Microbiol 2007 new
Nucleotide incorporation against 7,8-dihydro-8-oxoguanine is influenced by neighboring base sequences in TLS DNA polymerase reaction. Chinwei Yung, Tetsuya Suzuki, Yoji Okugawa, Asako Kawakami, David Loakes, Kazuo Negishi, Tomoe Negishi Nucleic Acids Symp Ser (Oxf) 2007 new
INCURVATA2 encodes the catalytic subunit of DNA Polymerase alpha and interacts with genes involved in chromatin-mediated cellular memory in Arabidopsis thaliana. José María Barrero, Rebeca González-Bayón, Juan Carlos del Pozo, María Rosa Ponce, José Luis Micol Plant Cell 2007 new
Anti-HIV drugs. Erik De Clercq Verhandelingen - Koninklijke Academie voor Geneeskunde van België 2007 pols set
Selective inhibition of porcine endogenous retrovirus replication in human cells by acyclic nucleoside phosphonates. Minyi Shi, Xin Wang, Erik De Clercq, Sonshin Takao, Masanori Baba Antimicrobial agents and chemotherapy 2007 new
Synthesis and evaluation of 2-(2,6-dihalophenyl)-3-pyrimidinyl-1,3-thiazolidin-4-one analogues as anti-HIV-1 agents. Ravindra K Rawal, Rajkamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq Bioorganic & medicinal chemistry 2007 pols set
A novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase delta. Sufang Zhang, Yanjiao Zhou, Sandra Trusa, Xiao Meng, Ernest Y C Lee, Marietta Y W T Lee The Journal of biological chemistry 2007 pols set
Decreased PARP-1 levels accelerate embryonic lethality but attenuate neuronal apoptosis in DNA polymerase beta-deficient mice. Noriyuki Sugo, Naoko Niimi, Yasuaki Aratani, Mitsuko Masutani, Hiroshi Suzuki, Hideki Koyama Biochem Biophys Res Commun 2007 new
Mechanism of template-independent nucleotide incorporation catalyzed by a template-dependent DNA polymerase. Kevin A Fiala, Jessica A Brown, Hong Ling, Ajay K Kshetry, Jun Zhang, John-Stephen Taylor, Wei Wen Yang, Zucai Suo Journal of molecular biology 2007 topics set
Synthesis of novel derivatives of 4-amino-3-(2-furyl)-5-mercapto-1,2,4-triazole as potential HIV-1 NNRTIs. Jingde Wu, Xinyong Liu, Xianchao Cheng, Yuan Cao, Defeng Wang, Zhongjie Li, Wenfang Xu, Christophe Pannecouque, Myriam Witvrouw, Erik De Clercq Molecules (Basel, Switzerland) 2007 pols set
The intricate structural chemistry of base excision repair machinery: implications for DNA damage recognition, removal, and repair. Kenichi Hitomi, Shigenori Iwai, John A Tainer DNA repair 2007 new
Characterization of a replication-competent, integrase-defective human immunodeficiency virus (HIV)/simian virus 40 chimera as a powerful tool for the discovery and validation of HIV integrase inhibitors. Dirk Daelemans, Richard Lu, Erik De Clercq, Alan Engelman Journal of virology 2007 pols set
Synthesis and biological evaluation of 2,3-diaryl substituted-1,3-thiazolidin-4-ones as anti-HIV agents. Ravindra K Rawal, Raj Kamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq Medicinal chemistry (Shāriqah (United Arab Emirates)) 2007 pols set
One-step purification of Taq DNA polymerase using nucleotide-mimetic affinity chromatography. Sotirios Melissis, Nikolaos E Labrou, Yannis D Clonis Biotechnol J 2007 pols set
Probing DNA polymerase-DNA interactions: examining the template strand in exonuclease complexes using 2-aminopurine fluorescence and acrylamide quenching. Dina Tleugabulova, Linda J Reha-Krantz Biochemistry 2007 complete
Identification, transcriptional and phylogenetic analysis of the DNA polymerase gene of Pieris rapae granulovirus. Ronghui Wen, Rong Ou, Baoshan Chen Virus genes 2007 new
A second proliferating cell nuclear antigen loader complex, Ctf18-replication factor C, stimulates DNA polymerase eta activity. Yasushi Shiomi, Chikahide Masutani, Fumio Hanaoka, Hiroshi Kimura, Toshiki Tsurimoto The Journal of biological chemistry 2007 new
Elevated expression of DNA polymerase II increases spontaneous mutagenesis in Escherichia coli. Abu Amar M Al Mamun Mutation research 2007 pols set
A dideoxynucleotide-sensitive DNA polymerase activity characterized from endoreduplicating cells of mungbean (Vigna radiata L.) during ontogeny of cotyledons. Sujit Roy, Sailendra Nath Sarkar, Sanjay Kumar Singh, Dibyendu Narayan SenGupta FEBS J 2007 new
Role of the 5' --> 3' exonuclease and Klenow fragment of Escherichia coli DNA polymerase I in base mismatch repair. Masaru Imai, Yu-ichiro Tago, Makoto Ihara, Masakado Kawata, Kazuo Yamamoto Mol Genet Genomics 2007 pols set
Synthesis and anti-HIV-1 activity evaluation of 5-alkyl-2-alkylthio-6-(arylcarbonyl or alpha-cyanoarylmethyl)-3,4-dihydropyrimidin-4(3H)-ones as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. Lei Ji, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Journal of medicinal chemistry 2007 pols set
Molecular modeling benzo[a]pyrene N2-dG adducts in the two overlapping active sites of the Y-family DNA polymerase Dpo4. Sushil Chandani, Edward L Loechler J Mol Graph Model 2007 topics set
Variations in reverse transcriptase and RNase H domain mutations in human immunodeficiency virus type 1 clinical isolates are associated with divergent phenotypic resistance to zidovudine. Michel L Ntemgwa, Mark A. Wainberg, Maureen Oliveira, Daniela D Moisi, Richard G Lalonde, Valeria Micheli, Bluma G Brenner Antimicrobial agents and chemotherapy 2007 new
Kinetics of inhibition of HIV type 1 reverse transcriptase-bearing NRTI-associated mutations by apricitabine triphosphate. Fernando A Frankel, Dimitrios Coutsinos, Hongtao Xu, Mark A. Wainberg Antiviral chemistry & chemotherapy 2007 pols set
Malignant transformation of the cultured human normal biliary tract epithelial cells induced by hepatitis C virus core protein. Ru-Fu Chen, Zhi-Hua Li, Ran-Yi Liu, Xian-He Kong, Qi-Bin Tang, Jie Wang Oncology reports 2007 new
Comparison of two gel filtration chromatographic methods for the purification of Lily symptomless virus. Ruoyu Wang, Jianhui Wang, Jinming Li, Yujue Wang, Zhongkui Xie, Lizhe An Journal of virological methods 2007 new
D- and L-2',3'-didehydro-2',3'-dideoxy-3'-fluoro-carbocyclic nucleosides: synthesis, anti-HIV activity and mechanism of resistance. Jianing Wang, Yunho Jin, Kimberly L Rapp, Raymond F Schinazi, Chung K Chu Journal of medicinal chemistry 2007 pols set
A peptide with HIV-1 reverse transcriptase inhibitory activity from the medicinal mushroom Russula paludosa. Jianbin Wang, H X Wang, T B Ng Peptides 2007 pols set
[DNA methylation of human telomerase reverse transcriptase promoter region in human ameloblastoma]. Ming Zhong, Ying Yan, Jie Wang, Jie Liu, Le Li, Yan-Bing Gong Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 2007 new
Site-directed mutagenesis in the fingers subdomain of HIV-1 reverse transcriptase reveals a specific role for the beta3-beta4 hairpin loop in dNTP selection. Scott J Garforth, Tae Woo Kim, Michael A. Parniak, Eric T Kool, Vinayaka R Prasad Journal of molecular biology 2007 pols set
Increased single-nucleotide discrimination in allele-specific polymerase chain reactions through primer probes bearing nucleobase and 2'-deoxyribose modifications. Ramon Kranaster, Andreas Marx Chemistry (Weinheim an der Bergstrasse, Germany) 2007 new
An importin alpha/beta-recognized bipartite nuclear localization signal mediates targeting of the human herpes simplex virus type 1 DNA polymerase catalytic subunit pUL30 to the nucleus. Gualtiero Alvisi, Daniele Musiani, David A Jans, Alessandro Ripalti Biochemistry 2007 new
Model for forward polymerization and switching transition between polymerase and exonuclease sites by DNA polymerase molecular motors. Ping Xie Arch Biochem Biophys 2007 new
Rationally designed dual inhibitors of HIV reverse transcriptase and integrase. Zhengqiang Wang, Eric M Bennett, Daniel J Wilson, Christine E Salomon, Robert Vince Journal of medicinal chemistry 2007 pols set
Evolution of a novel 5-amino-acid insertion in the beta3-beta4 loop of HIV-1 reverse transcriptase. Marleen C D G Huigen, Loek de Graaf, Dirk Eggink, Rob Schuurman, Viktor Müller, Anna Stamp, David K Stammers, Charles A B Boucher, Monique Nijhuis Virology 2007 topics set
Clonally amplified cardiac stem cells are regulated by Sca-1 signaling for efficient cardiovascular regeneration. Kento Tateishi, Eishi Ashihara, Naofumi Takehara, Tetsuya Nomura, Shoken Honsho, Takuo Nakagami, Shigehiro Morikawa, Tomosaburo Takahashi, Tomomi Ueyama, Hiroaki Matsubara, Hidemasa Oh Journal of cell science 2007 new
Characterization of the DNA- and dNTP-binding activities of the human cytomegalovirus DNA polymerase catalytic subunit UL54. Frédéric Picard-Jean, Isabelle Bougie, Martin Bisaillon Biochem J 2007 pols set
DNA polymerase delta-dependent repair of DNA single strand breaks containing 3'-end proximal lesions. Jason L Parsons, Bradley D Preston, Timothy R O'Connor, Grigory L Dianov Nucleic acids research 2007 new
The role of specific amino acid residues in the active site of Escherichia coli DNA polymerase I on translesion DNA synthesis across from and past an N-2-aminofluorene adduct. Samer Lone, Louis J Romano Biochemistry 2007 pols set
Sulfolobus solfataricus DNA polymerase Dpo4 is partially inhibited by "wobble" pairing between O6-methylguanine and cytosine, but accurate bypass is preferred. Robert Lawton Eoff, Adriana Irimia, Martin Egli, F Peter Guengerich The Journal of biological chemistry 2007 topics set
RNA-templated DNA repair. Francesca Storici, Katarzyna Bebenek, Thomas A Kunkel, Dmitry A Gordenin, Michael A Resnick Nature 2007 new
NNRTI-selected mutations at codon 190 of human immunodeficiency virus type 1 reverse transcriptase decrease susceptibility to stavudine and zidovudine. Stefania Paolucci, Fausto Baldanti, Giulia Campanini, Reynel Cancio, Amalia Belfiore, Giovanni Maga, Giuseppe Gerna Antiviral research 2007 pols set
Indolyl aryl sulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: role of two halogen atoms at the indole ring in developing new analogues with improved antiviral activity. Giuseppe La Regina, Antonio Coluccia, Francesco Piscitelli, Alberto Bergamini, Anna Sinistro, Antonella Cavazza, Giovanni Maga, Alberta Samuele, Samantha Zanoli, Ettore Novellino, Marino Artico, Romano Silvestri Journal of medicinal chemistry 2007 pols set
Investigation of novel lipid-functionalized PNA monomers as potential HIV-1 non-nucleoside reverse transcriptase and/or integrase inhibitors. Michael G Thomas, Giovanni Maga, Jean-François Mouscadet, Nicola M Howarth Nucleosides, nucleotides & nucleic acids 2007 pols set
Differing conformational pathways before and after chemistry for insertion of dATP versus dCTP opposite 8-oxoG in DNA polymerase beta. Yazhen Wang, Sujatha Reddy, William A Beard, Samuel H Wilson, Tamar Schlick Biophys J 2007 pols set
Different mutations in the HHV-6 DNA polymerase gene accounting for resistance to foscarnet. Pascale Bonnafous, Lieve Naesens, Stéphanie Petrella, Agnès Gautheret-Dejean, David Boutolleau, Wladimir Sougakoff, Henri Agut Antivir Ther 2007 new
Anti-tumor effects of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha. Naoki Maeda, Yasuo Kokai, Seiji Ohtani, Hiroeki Sahara, Isoko Kuriyama, Shinji Kamisuki, Shunya Takahashi, Kengo Sakaguchi, Fumio Sugawara, Hiromi Yoshida, Noriyuki Sato, Yoshiyuki Mizushina Biochem Biophys Res Commun 2007 pols set
Highly tolerated amino acid substitutions increase the fidelity of Escherichia coli DNA polymerase I. Ern Loh, Juno Choe, Lawrence A Loeb The Journal of biological chemistry 2007 pols set
Conformational changes during normal and error-prone incorporation of nucleotides by a Y-family DNA polymerase detected by 2-aminopurine fluorescence. Angela M DeLucia, Nigel D F Grindley, Catherine M Joyce Biochemistry 2007 new
Inhibition of telomerase activity and human telomerase reverse transcriptase gene expression by histone deacetylase inhibitor in human brain cancer cells. Aik Kia Khaw, Miranti Silasudjana, Birendranath Banerjee, Motoshi Suzuki, Rajamanickam Baskar, M Prakash Hande Mutation research 2007 new
Biochemical properties of a plastidial DNA polymerase of rice. Ryo Takeuchi, Seisuke Kimura, Ai Saotome, Kengo Sakaguchi Plant Mol Biol 2007 new
Steric and electrostatic effects in DNA synthesis by the SOS-induced DNA polymerases II and IV of Escherichia coli. Adam P Silverman, Qingfei Jiang, Myron F Goodman, Eric T Kool Biochemistry 2007 topics set
Simian fetal brain progenitor cells for studying viral neuropathogenesis. Naoko Iwata, Hiroaki Yoshida, Minoru Tobiume, Fumiko Ono, Takuya Shimazaki, Tetsutaro Sata, Noriko Nakajima Journal of neurovirology 2007 pols set
An efficient method for the construction of functionalized DNA bearing amino acid groups through cross-coupling reactions of nucleoside triphosphates followed by primer extension or PCR. Petr Capek, Hana Cahová, Radek Pohl, Michal Hocek, Christian Gloeckner, Andreas Marx Chemistry (Weinheim an der Bergstrasse, Germany) 2007 new
A highly conserved Tyrosine residue of family B DNA polymerases contributes to dictate translesion synthesis past 8-oxo-7,8-dihydro-2'-deoxyguanosine. Miguel de Vega, Margarita Salas Nucleic acids research 2007 topics set
Mutagenic bypass of the butadiene-derived 2'-deoxyuridine adducts by polymerases eta and zeta. PriscillaH Fernandes, RStephen Lloyd Mutation research 2007 topics set
Directed DNA polymerase evolution: effects of mutations in motif C on the mismatch-extension selectivity of thermus aquaticus DNA polymerase. Michael Strerath, Christian Gloeckner, Dan Liu, Andreas Schnur, Andreas Marx Chembiochem 2007 topics set
DNA polymerase beta null mouse embryonic fibroblasts harbor a homozygous null mutation in DNA polymerase iota. Robert W Sobol DNA repair 2007 complete Robert W Sobol*
Dynamic DNA helicase-DNA polymerase interactions assure processive replication fork movement. Samir M Hamdan, Donald E Johnson, Nathan A Tanner, Jong-Bong Lee, Udi Qimron, Stanley Tabor, Antoine M van Oijen, Charles C Richardson Molecular cell 2007 pols set
Ribavirin and mycophenolic acid markedly potentiate the anti-hepatitis B virus activity of entecavir. Chunxiao Ying, Richard Colonno, Erik De Clercq, Johan Neyts Antiviral research 2007 new
DNA polymerase proofreading: active site switching catalyzed by the bacteriophage T4 DNA polymerase. Elizabeth Fidalgo da Silva, Linda J Reha-Krantz Nucleic acids research 2007 complete
The unstructured C-terminus of the tau subunit of Escherichia coli DNA polymerase III holoenzyme is the site of interaction with the alpha subunit. Slobodan Jergic, Kiyoshi Ozawa, Neal K Williams, Xun-Cheng Su, Daniel D Scott, Samir M Hamdan, Jeffrey A Crowther, Gottfried Otting, Nicholas E Dixon Nucleic acids research 2007 pols set
Specific interactions of three proliferating cell nuclear antigens with replication-related proteins in Aeropyrum pernix. Kaori Imamura, Kenzo Fukunaga, Yutaka Kawarabayasi, Yoshizumi Ishino Molecular microbiology 2007 topics set
Genomewide and biochemical analyses of DNA-binding activity of Cdc6/Orc1 and Mcm proteins in Pyrococcus sp. Fujihiko Matsunaga, Annie Glatigny, Marie-Hélène Mucchielli-Giorgi, Nicolas Agier, Hervé Delacroix, Laetitia Marisa, Patrice Durosay, Yoshizumi Ishino, Lawrence Aggerbeck, Patrick Forterre Nucleic acids research 2007 new
The active site residue Valine 867 in human telomerase reverse transcriptase influences nucleotide incorporation and fidelity. William C Drosopoulos, Vinayaka R Prasad Nucleic acids research 2007 partial results
Crystal structure of the GINS complex and functional insights into its role in DNA replication. Y Paul Chang, Ganggang Wang, Vladimir Bermudez, Jerard Hurwitz, Xiaojiang S Chen Proceedings of the National Academy of Sciences of the United States of America 2007 new
Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1. Zabrina L Brumme, Chanson J Brumme, David Heckerman, Bette T Korber, Marcus Daniels, Jonathan Carlson, Carl Kadie, Tanmoy Bhattacharya, Celia K S Chui, James Szinger, Theresa Mo, Robert S Hogg, Julio S G Montaner, Nicole Frahm, Christian Brander, Bruce D Walker, P Richard Harrigan PLoS Pathog 2007 new
Involvement of DNA polymerase mu in the repair of a specific subset of DNA double-strand breaks in mammalian cells. Jean-Pascal Capp, François Boudsocq, Anne-Gaelle Besnard, Bernard S Lopez, Christophe Cazaux, Jean-Sébastien Hoffmann, Yvan Canitrot Nucleic acids research 2007 new
Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. Bruno Marchand, Kirsten L White, John K Ly, Nicolas A Margot, Ruth Wang, Martin J McDermott, Michael D Miller, Matthias Götte Antimicrob Agents Chemother 2007 topics set
Single-step purification of recombinant Thermus aquaticus DNA polymerase using DNA-aptamer immobilized novel affinity magnetic beads. Huseyin Avni Oktem, Gulay Bayramoglu, V Cengiz Ozalp, M Yakup Arica Biotechnol Prog 2007 pols set
Structure/function analysis of the interaction of adenomatous polyposis coli with DNA polymerase beta and its implications for base excision repair. Ramesh Balusu, Aruna S Jaiswal, Melissa L Armas, Chanakya N Kundu, Linda B Bloom, Satya Narayan Biochemistry 2007 new
Insertions in the beta3-beta4 loop of reverse transcriptase of human immunodeficiency virus type 1 and their mechanism of action, influence on drug susceptibility and viral replication capacity. Dirk Eggink, Marleen C D G Huigen, Charles A B Boucher, Matthias Götte, Monique Nijhuis Antiviral Res 2007 topics set
Reassessment of the in vivo functions of DNA polymerase I and RNase H in bacterial cell growth. Sanae Fukushima, Mitsuhiro Itaya, Hiroaki Kato, Naotake Ogasawara, Hirofumi Yoshikawa J Bacteriol 2007 new
Study of interaction of XRCC1 with DNA and proteins of base excision repair by photoaffinity labeling technique. Zh K Nazarkina, Svetlana N Khodyreva, Stéphanie Marsin, J Pablo Radicella, Olga I Lavrik Biochemistry. Biokhimii͡a 2007 new
Werner syndrome protein interacts functionally with translesion DNA polymerases. Ashwini S Kamath-Loeb, Li Lan, Satoshi Nakajima, Akira Yasui, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 2007 new
The dnaE173 mutator mutation confers on the alpha subunit of Escherichia coli DNA polymerase III a capacity for highly processive DNA synthesis and stable binding to primer/template DNA. Fusamitsu Yanagihara, Shonen Yoshida, Yutaka Sugaya, Hisaji Maki Genes Genet Syst 2007 pols set
Error-free bypass of 2-hydroxyadenine by human DNA polymerase lambda with Proliferating Cell Nuclear Antigen and Replication Protein A in different sequence contexts. Emmanuele Crespan, Ulrich Hübscher, Giovanni Maga Nucleic acids research 2007 pols set
Characterization of a triple DNA polymerase replisome. Peter McInerney, Aaron Johnson, Francine Katz, Mike E O'Donnell Molecular cell 2007 new
Relationship of potency and resilience to drug resistant mutations for GW420867X revealed by crystal structures of inhibitor complexes for wild-type, Leu100Ile, Lys101Glu, and Tyr188Cys mutant HIV-1 reverse transcriptases. Jingshan Ren, Charles E Nichols, Phillip P Chamberlain, Kurt L Weaver, Steven A Short, Joseph H Chan, Jörg-Peter Kleim, David K Stammers J Med Chem 2007 partial results
Performance of a World Health Organization first-line regimen (stavudine/lamivudine/nevirapine) in antiretroviral-naive individuals in a Western setting. L W Y Tam, Robert S Hogg, Benita Yip, J S G Montaner, P Richard Harrigan, Chanson J Brumme HIV Med 2007 new
Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family. Matthew Hogg, Pierre Aller, William H Konigsberg, Susan S Wallace, Sylvie Doublié The Journal of biological chemistry 2007 complete
Increased single nucleotide discrimination in arrayed primer elongation by 4'C-modified primer probes. Jens Gaster, Gopinath Rangam, Andreas Marx Chemical communications (Cambridge, England) 2007 new
Interactions of the DNA polymerase X from African swine fever virus with gapped DNA substrates. Quantitative analysis of functional structures of the formed complexes. Maria J Jezewska, Paul J Bujalowski, Wlodzimierz Bujalowski Biochemistry 2007 new
Chemical biology of DNA polymerases: from selectivity to new functions. Andreas Marx, Daniel Summerer, Katharina B M Sauter, Christian Gloeckner, Nicolas Z Rudinger Nucleic acids symposium series (2004) 2007 new
Nodulisporol and Nodulisporone, novel specific inhibitors of human DNA polymerase lambda from a fungus, Nodulisporium sp. Shinji Kamisuki, Chisato Ishimaru, Kadohiro Onoda, Isoko Kuriyama, Noriko Ida, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Bioorg Med Chem 2007 pols set
DNA polymerase V allows bypass of toxic guanine oxidation products in vivo. William L Neeley, Sarah Delaney, Yuriy O Alekseyev, Daniel F Jarosz, James C Delaney, Graham C Walker, John M Essigmann The Journal of biological chemistry 2007 new
Involvement of DNA polymerase beta in repair of ionizing radiation damage as measured by in vitro plasmid assays. Conchita Vens, Ingrid Hofland, Adrian C Begg Radiat Res 2007 new
The accessory subunit B of DNA polymerase gamma is required for mitochondrial replisome function. Géraldine Farge, Xuan Hoi Pham, Teresa Holmlund, Ivan Khorostov, Maria Falkenberg Nucleic acids research 2007 new
Magnesium-cationic dummy atom molecules enhance representation of DNA polymerase beta in molecular dynamics simulations: improved accuracy in studies of structural features and mutational effects. Peter Oelschlaeger, Marco Klahn, William A Beard, Samuel H Wilson, Arieh Warshel Journal of molecular biology 2007 pols set
Assay of HIV gp41 amino acid sequence to identify baseline variation and mutation development in patients with virologic failure on enfuvirtide. M R Loutfy, J M Raboud, J S G Montaner, T Antoniou, Brian Wynhoven, F Smaill, D Rouleau, J Gill, W Schlech, Zabrina L Brumme, Theresa Mo, K Gough, A Rachlis, P Richard Harrigan, S L Walmsley Antiviral Res 2007 new
Accessory proteins assist exonuclease-deficient bacteriophage T4 DNA polymerase in replicating past an abasic site. Giuseppina Blanca, Emmanuelle Delagoutte, Nicolas Tanguy Le Gac, Neil P Johnson, Giuseppe Baldacci, Giuseppe Villani Biochem J 2007 pols set
Bayesian network analysis of resistance pathways against HIV-1 protease inhibitors. K Deforche, R Camacho, Z Grossman, T Silander, M A Soares, Y Moreau, R W Shafer, Kristel Van Laethem, A P Carvalho, Brian Wynhoven, P Cane, Joke Snoeck, J Clarke, S Sirivichayakul, Koyo Ariyoshi, A Holguin, H Rudich, R Rodrigues, M B Bouzas, P Cahn, L F Brigido, V Soriano, Wataru Sugiura, P Phanuphak, L Morris, J Weber, D Pillay, A Tanuri, P Richard Harrigan, J M Shapiro, D A Katzenstein, R Kantor, A-M Vandamme Infect Genet Evol 2007 new
Structural descriptors of gp120 V3 loop for the prediction of HIV-1 coreceptor usage. Oliver Sander, Tobias Sing, Ingolf Sommer, Andrew J Low, Peter K Cheung, P Richard Harrigan, Thomas Lengauer, Francisco S Domingues PLoS Comput Biol 2007 new
Chemical properties of fatty acid derivatives as inhibitors of DNA polymerases. Ryoichi Nakamura, Ryo Takeuchi, Kouji Kuramochi, Yoshiyuki Mizushina, Chisato Ishimaru, Yoichi Takakusagi, Masaharu Takemura, Susumu Kobayashi, Hiromi Yoshida, Fumio Sugawara, Kengo Sakaguchi Organic & biomolecular chemistry 2007 new
Mechanism of cell cycle arrest and apoptosis induction by conjugated eicosapentaenoic acid, which is a mammalian DNA polymerase and topoisomerase inhibitor. Yuko Yonezawa, Takahiko Hada, Keisuke Uryu, Tsuyoshi Tsuzuki, Kiyotaka Nakagawa, Teruo Miyazawa, Hiromi Yoshida, Yoshiyuki Mizushina International journal of oncology 2007 new
Tobacco proliferating cell nuclear antigen binds directly and stimulates both activity and processivity of ddNTP-sensitive mungbean DNA polymerase. Sujit Roy, Swarup Roy Choudhury, Sunil K Mukherjee, Dibyendu Narayan SenGupta Arch Biochem Biophys 2007 new
Human DNA polymerase kappa encircles DNA: implications for mismatch extension and lesion bypass. Samer Lone, Sharon A Townson, Sacha N Uljon, Robert E Johnson, Amrita Brahma, Deepak T Nair, Satya Prakash, Louise Prakash, Aneel K Aggarwal Molecular cell 2007 pols set
The DNA polymerase gamma Y955C disease variant associated with PEO and parkinsonism mediates the incorporation and translesion synthesis opposite 7,8-dihydro-8-oxo-2'-deoxyguanosine. Maria A Graziewicz, Rachelle J Bienstock, William C Copeland Human molecular genetics 2007 new
Mutations at 65 and 70 within the context of a Q151M cluster in human immunodeficiency virus type 1 reverse transcriptase impact the susceptibility to the different nucleoside reverse transcriptase inhibitors in distinct ways. Kristel Van Laethem, Christophe Pannecouque, Anne-Mieke Vandamme Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2007 pols set
Synthesis and biological evaluation of alkenyldiarylmethane HIV-1 non-nucleoside reverse transcriptase inhibitors that possess increased hydrolytic stability. Matthew D Cullen, Bo-Liang Deng, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman Journal of medicinal chemistry 2007 pols set
Mutations in human immunodeficiency virus type 1 RNase H primer grip enhance 3'-azido-3'-deoxythymidine resistance. Krista A Delviks-Frankenberry, Galina N Nikolenko, Rebekah Barr, Vinay K Pathak J Virol 2007 topics set
Lessons from 50 years of SOS DNA-damage-induced mutagenesis. Katharina Schlacher, Myron F Goodman Nature reviews. Molecular cell biology 2007 new
Genome-wide analysis of the core DNA replication machinery in the higher plants Arabidopsis and rice. Randall W Shultz, Vinaya M Tatineni, Linda Hanley-Bowdoin, William F Thompson Plant Physiol 2007 topics set
A 21-base pair insertion/duplication at codon 69 of the HIV type 1 reverse transcriptase in a patient undergoing multiple nucleoside therapy. P Richard Harrigan, Theresa Mo, Jennifer Hirsch, Zabrina L Brumme, Paula McKenna, Lee Bacheler AIDS Res Hum Retroviruses 2007 topics set
A water-mediated and substrate-assisted catalytic mechanism for Sulfolobus solfataricus DNA polymerase IV. Liming Wang, Xinyun Yu, Po Hu, Suse Broyde, Yongqing Zhang Journal of the American Chemical Society 2007 topics set
Synthesis of AZTpSpCX2ppSA and AZTpSpCX2ppSAZT: hydrolysis-resistant potential inhibitors of the AZT excision reaction of HIV-1 RT. Qianwei Han, Stefan G Sarafianos, Edward Arnold, Michael A. Parniak, Barbara L Gaffney, Roger A Jones Organic letters 2007 pols set
Sloppy bypass of an abasic lesion catalyzed by a Y-family DNA polymerase. Kevin A Fiala, Zucai Suo The Journal of biological chemistry 2007 topics set
40 years with bacteriophage ø29. Margarita Salas Annual review of microbiology 2007 new
Fluorescence of 2-aminopurine reveals rapid conformational changes in the RB69 DNA polymerase-primer/template complexes upon binding and incorporation of matched deoxynucleoside triphosphates. Haijiang Zhang, W Cao, E Zakharova, William H Konigsberg, E M De La Cruz Nucleic acids research 2007 complete
Mutator alleles of yeast DNA polymerase zeta. Ayako N Sakamoto, Jana E Stone, Grace E Kissling, Scott D McCulloch, Youri I Pavlov, Thomas A Kunkel DNA repair 2007 new
DNA damage reduces Taq DNA polymerase fidelity and PCR amplification efficiency. Jan A Sikorsky, Donald A Primerano, Terry W Fenger, James Denvir Biochem Biophys Res Commun 2007 topics set
DNA polymerase mutations in drug-resistant herpes simplex virus mutants determine in vivo neurovirulence and drug-enzyme interactions. Gracíela Andrei, Pierre Fiten, Matheus Froeyen, Erik De Clercq, Ghislain Opdenakker, Robert Snoeck Antivir Ther 2007 new
Methylation of DNA polymerase beta by protein arginine methyltransferase 1 regulates its binding to proliferating cell nuclear antigen. Nazim El-Andaloussi, Taras Valovka, Magali Toueille, Paul O Hassa, Peter Gehrig, Marcela Covic, Ulrich Hübscher, Michael O Hottiger FASEB J 2007 new
Analysis of DNA polymerase activity in vitro using non-radioactive primer extension assay in an automated DNA sequencer. D O Lopes, Carlos Gustavo Regis-da-Silva, Alice Machado-Silva, Andréa Mara Macedo, Glória Regina Franco, Jean-Sébastien Hoffmann, Christophe Cazaux, Sérgio Danilo Junho Pena, Santuza Maria Ribeiro Teixeira, Carlos Renato Machado Genet Mol Res 2007 new
Evolving a thermostable DNA polymerase that amplifies from highly damaged templates. Christian Gloeckner, Katharina B M Sauter, Andreas Marx Angew Chem Int Ed Engl 2007 new
Dimerization of the Klenow fragment of Escherichia coli DNA polymerase I is linked to its mode of DNA binding. Michael F Bailey, Edwin J C Van der Schans, David P Millar Biochemistry 2007 pols set
Coordination of steps in single-nucleotide base excision repair mediated by apurinic/apyrimidinic endonuclease 1 and DNA polymerase beta. Yuan Liu, Rajendra Prasad, William A Beard, Padmini S Kedar, Esther W Hou, David D Shock, Samuel H Wilson The Journal of biological chemistry 2007 new
Use of damaged DNA and dNTP substrates by the error-prone DNA polymerase X from African swine fever virus. Sandeep Kumar, Brandon J Lamarche, Ming-Daw Tsai Biochemistry 2007 new
DNA polymerase eta is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse. Frédéric Delbos, Said Aoufouchi, Ahmad Faili, Jean-Claude Weill, Claude-Agnès Reynaud J Exp Med 2007 new
Mammary carcinogenesis in transgenic mice expressing a dominant-negative mutant of DNA polymerase beta in their mammary glands. Liming Wang, Nandan Bhattacharyya, Thangaiyan Rabi, Li Wang, Sanjeev Banerjee Carcinogenesis 2007 new
A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol. Pierre Aller, Mark A Rould, Matthew Hogg, Susan S Wallace, Sylvie Doublié Proceedings of the National Academy of Sciences of the United States of America 2007 topics set
Loop II of DNA polymerase beta is important for polymerization activity and fidelity. George C Lin, Joachim Jaeger, Joann B Sweasy Nucleic acids research 2007 topics set
HIV-1 drug resistance surveillance using dried whole blood spots. Silvia Bertagnolio, Luis Soto-Ramirez, Richard Pilon, Roberto Rodriguez, Monica Viveros, Luis Fuentes, P Richard Harrigan, Theresa Mo, Don Sutherland, Paul Sandstrom Antivir Ther 2007 new
Efficient and erroneous incorporation of oxidized DNA precursors by human DNA polymerase eta. Masatomi Shimizu, Petr Grúz, Hiroyuki Kamiya, Chikahide Masutani, Yan Xu, Yukio Usui, Hiroshi Sugiyama, Hideyoshi Harashima, Fumio Hanaoka, Takehiko Nohmi Biochemistry 2007 pols set
Participation of the fingers subdomain of Escherichia coli DNA polymerase I in the strand displacement synthesis of DNA. Kamalendra Singh, Aashish Srivastava, Smita S Patel, Mukund J Modak The Journal of biological chemistry 2007 pols set
Epicatechin conjugated with fatty acid is a potent inhibitor of DNA polymerase and angiogenesis. Kiminori Matsubara, Akiko Saito, Akira Tanaka, Noriyuki Nakajima, Reiko Akagi, Masaharu Mori, Yoshiyuki Mizushina Life Sci 2007 new
Single-turnover kinetic analysis of the mutagenic potential of 8-oxo-7,8-dihydro-2'-deoxyguanosine during gap-filling synthesis catalyzed by human DNA polymerases lambda and beta. Jessica A Brown, Wade W Duym, Jason D Fowler, Zucai Suo Journal of molecular biology 2007 pols set
Architecture of the bacteriophage T4 replication complex revealed with nanoscale biopointers. Nancy G Nossal, Alexander M Makhov, Paul D Chastain, Charles E Jones, Jack D Griffith The Journal of biological chemistry 2007 complete
DNA polymerase beta catalytic efficiency mirrors the Asn279-dCTP H-bonding strength. Václav Martínek, Urban Bren, Myron F Goodman, Arieh Warshel, Jan Florián FEBS letters 2007 pols set
3'-Azido-3'-deoxythymidine-(5')-tetraphospho-(5')-adenosine, the product of ATP-mediated excision of chain-terminating AZTMP, is a potent chain-terminating substrate for HIV-1 reverse transcriptase. Sanjeewa Dharmasena, Zita Pongracz, Edward Arnold, Stefan G Sarafianos, Michael A. Parniak Biochemistry 2007 partial results
Mitochondrial DNA defects in Saccharomyces cerevisiae caused by functional interactions between DNA polymerase gamma mutations associated with disease in human. Enrico Baruffini, Iliana Ferrero, Françoise Foury Biochimica et biophysica acta 2007 complete Enrico Baruffini*
Dynamics of human replication factors in the elongation phase of DNA replication. Yuji Masuda, Miki Suzuki, Jinlian Piao, Yongqing Gu, Toshiki Tsurimoto, Kenji Kamiya Nucleic acids research 2007 new
Multiple primer extension by DNA polymerase on a novel plastic DNA array coated with a biocompatible polymer. Kenji Kinoshita, Kentaro Fujimoto, Toru Yakabe, Shin Saito, Yuzo Hamaguchi, Takayuki Kikuchi, Ken Nonaka, Shigenori Murata, Daisuke Masuda, Wataru Takada, Sohei Funaoka, Susumu Arai, Hisao Nakanishi, Kanehisa Yokoyama, Kazuhiko Fujiwara, Kiminori Matsubara Nucleic acids research 2007 new
NtPolI-like1 and NtPolI-like2, bacterial DNA polymerase I homologs isolated from BY-2 cultured tobacco cells, encode DNA polymerases engaged in DNA replication in both plastids and mitochondria. Yuriko Ono, Atsushi Sakai, Katsuaki Takechi, Susumu Takio, Mari Takusagawa, Hiroyoshi Takano Plant Cell Physiol 2007 new
Effects of human leukocyte antigen class I genetic parameters on clinical outcomes and survival after initiation of highly active antiretroviral therapy. Zabrina L Brumme, Chanson J Brumme, Celia K S Chui, Theresa Mo, Brian Wynhoven, Conan K Woods, Bethany M Henrick, Robert S Hogg, Julio S G Montaner, P Richard Harrigan J Infect Dis 2007 new
Structural insight into the substrate specificity of DNA Polymerase mu. Andrea F Moon, Miguel Garcia-Diaz, Katarzyna Bebenek, Bryan J Davis, Xuejun Zhong, Dale A Ramsden, Thomas A Kunkel, Lars C Pedersen Nature structural & molecular biology 2007 topics set
Inefficient proofreading and biased error rates during inaccurate DNA synthesis by a mutant derivative of Saccharomyces cerevisiae DNA polymerase delta. Stephanie A Nick McElhinny, Carrie M W Stith, Peter M J Burgers, Thomas A Kunkel The Journal of biological chemistry 2007 topics set
Human base excision repair complex is physically associated to DNA replication and cell cycle regulatory proteins. Eleonora Parlanti, Giada A Locatelli, Giovanni Maga, Eugenia Dogliotti Nucleic acids research 2007 new
Targeting to the endoplasmic reticulum improves the folding of recombinant human telomerase reverse transcriptase. Chia-Kuei Wu, Karine Gousset, Stephen H Hughes Protein expression and purification 2007 new
UmuD and RecA directly modulate the mutagenic potential of the Y family DNA polymerase DinB. Veronica G Godoy, Daniel F Jarosz, Sharotka M Simon, Alexej Abyzov, Valentin A Ilyin, Graham C Walker Molecular cell 2007 new
Continued improvement in survival among HIV-infected individuals with newer forms of highly active antiretroviral therapy. Viviane Dias Lima, Robert S Hogg, P Richard Harrigan, David Moore, Benita Yip, Evan Wood, Julio S G Montaner Aids 2007 new
DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes. Keiji Masuda, Rika Ouchida, Masaki Hikida, Tomohiro Kurosaki, Masayuki Yokoi, Chikahide Masutani, Masayuki Seki, Richard D Wood, Fumio Hanaoka, Jiyang O-Wang The Journal of biological chemistry 2007 new
Rad54 dissociates homologous recombination intermediates by branch migration. Dmitry V Bugreev, Fumio Hanaoka, Alexander V Mazin Nature structural & molecular biology 2007 new
Analysis of amino acids in the beta7-beta8 loop of human immunodeficiency virus type 1 reverse transcriptase for their role in virus replication. Alok Mulky, B Christie Vu, Joan A Conway, Stephen H Hughes, John C Kappes Journal of molecular biology 2007 pols set
Hypersensitivity phenotypes associated with genetic and synthetic inhibitor-induced base excision repair deficiency. Julie K Horton, Samuel H Wilson DNA repair 2007 new
Interplay between DNA polymerases beta and lambda in repair of oxidation DNA damage in chicken DT40 cells. Keizo Tano, Jun Nakamura, Kenjiro Asagoshi, Hiroshi Arakawa, Eiichiro Sonoda, Elena K Braithwaite, Rajendra Prasad, Jean-Marie Buerstedde, Shunichi Takeda, Masami Watanabe, Samuel H Wilson DNA repair 2007 new
Different structural states in oligonucleosomes are required for early versus late steps of base excision repair. Shima Nakanishi, Rajendra Prasad, Samuel H Wilson, Michael J Smerdon Nucleic acids research 2007 new
Increased flexibility enhances misincorporation: temperature effects on nucleotide incorporation opposite a bulky carcinogen-DNA adduct by a Y-family DNA polymerase. Rebecca A Perlow-Poehnelt, Ilya Likhterov, Liming Wang, David A Scicchitano, Nicholas E Geacintov, Suse Broyde The Journal of biological chemistry 2007 partial results
The roles of Tyr391 and Tyr619 in RB69 DNA polymerase replication fidelity. Agata Jacewicz, Karolina Makiela, Andrzej Kierzek, John W Drake, Anna Bebenek Journal of molecular biology 2007 complete
Herpes simplex virus mutants with multiple substitutions affecting DNA binding of UL42 are impaired for viral replication and DNA synthesis. Changying Jiang, Ying T Hwang, Guangliang Wang, John C W Randell, Donald M Coen, Charles B C Hwang Journal of virology 2007 new
A ubiquitin-binding motif in the translesion DNA polymerase Rev1 mediates its essential functional interaction with ubiquitinated proliferating cell nuclear antigen in response to DNA damage. Adam Wood, Parie Garg, Peter M J Burgers The Journal of biological chemistry 2007 new
Multiple functions of DNA polymerases. Miguel Garcia-Diaz, Katarzyna Bebenek Critical reviews in plant sciences 2007 new
2-Hydroxy-2'-deoxyadenosine 5'-triphosphate enhances A.T --> C.G mutations caused by 8-hydroxy-2'-deoxyguanosine 5'-triphosphate by suppressing its degradation upon replication in a HeLa extract. Kazuya Satou, Hironori Kasai, Chikahide Masutani, Fumio Hanaoka, Hideyoshi Harashima, Hiroyuki Kamiya Biochemistry 2007 new
Stimulation of NEIL2-mediated oxidized base excision repair via YB-1 interaction during oxidative stress. Soumita Das, Ranajoy Chattopadhyay, Kishor K Bhakat, Istvan Boldogh, Kimitoshi Kohno, Rajendra Prasad, Samuel H Wilson, Tapas K Hazra The Journal of biological chemistry 2007 new
[Evolutionary characterization of HA1 of influenza H1N1 hemagglutinin gene surveyed in 1981-2005 in China]. Jia-Huai Zhang, Hong Xu, Yongqing Zhang, Xiang Zhao, Jun-Feng Guo, Yu Lan, Yue-Long Shu Bing du xue bao = Chinese journal of virology / [bian ji, Bing du xue bao bian ji wei yuan hui] 2007 new
"False" thymine-1H-Enol guanine base pair. low misinsertion rate by DNA polymerase explained by computational chemistry consideration. E Seclaman, L Kurunczi, Z Simon Biochemistry (Mosc) 2007 new
Down-regulation of DNA polymerase beta accompanies somatic hypermutation in human BL2 cell lines. Vladimir P Poltoratsky, Rajendra Prasad, Julie K Horton, Samuel H Wilson DNA repair 2007 new
Proteomic analysis of p16ink4a-binding proteins. Elielson Souza-Rodrígues, Josep M Estanyol, Erica Friedrich-Heineken, Eva Olmedo, Jorge Vera, Nuria Canela, Sonia Brun, Neus Agell, Ulrich Hübscher, Oriol Bachs, Montserrat Jaumot Proteomics 2007 new
Binding parameters and thermodynamics of the interaction of the human cytomegalovirus DNA polymerase accessory protein, UL44, with DNA: implications for the processivity mechanism. Arianna Loregian, Elisa Sinigalia, Beatrice Mercorelli, Giorgio Palù, Donald M Coen Nucleic acids research 2007 pols set
Expression of human telomerase reverse transcriptase (hTERT) protein is significantly associated with the progression, recurrence and prognosis of oral squamous cell carcinoma in Taiwan. Huang-Hsu Chen, Chuan-Hang Yu, Jeng-Tzung Wang, Bu-Yuan Liu, Yi-Ping Wang, Andy Sun, Tung-Chieh Tsai, Chun-Pin Chiang Oral oncology 2007 new
Incorporation of human immunodeficiency virus type 1 reverse transcriptase into virus-like particles. Wei-Hao Liao, Kuo-Jung Huang, Yu-Fen Chang, Shiu-Mei Wang, Ying-Tzu Tseng, Chien-Cheng Chiang, Jaang-Jiun Wang, Chin-Tien Wang Journal of virology 2007 pols set
A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment. Jacob Bauer, Guangxin Xing, Haruhiko Yagi, Jane M Sayer, Donald M Jerina, Hong Ling Proceedings of the National Academy of Sciences of the United States of America 2007 topics set
The noncatalytic C-terminus of AtPOLK Y-family DNA polymerase affects synthesis fidelity, mismatch extension and translesion replication. María Victoria García-Ortiz, Teresa Roldán-Arjona, Rafael R Ariza FEBS J 2007 complete Rafael R Ariza*
Role of Escherichia coli DNA polymerase I in conferring viability upon the dnaN159 mutant strain. Robert W Maul, Laurie H Sanders, James B Lim, Rosemary Benitez, Mark D Sutton J Bacteriol 2007 pols set
A unique error signature for human DNA polymerase nu. Mercedes E Arana, Kei-ichi Takata, Miguel Garcia-Diaz, Richard D Wood, Thomas A Kunkel DNA repair 2007 partial results
Discovery of non-nucleoside inhibitors of HIV-1 reverse transcriptase competing with the nucleotide substrate. Giovanni Maga, Marco Radi, Samantha Zanoli, Fabrizio Manetti, Reynel Cancio, Ulrich Hübscher, Silvio Spadari, Chiara Falciani, Montserrat Terrazas, Jaume Vilarrasa, Maurizio Botta Angewandte Chemie (International ed. in English) 2007 pols set
Human DNA polymerase alpha uses a combination of positive and negative selectivity to polymerize purine dNTPs with high fidelity. Jeff W Beckman, Kristi Kincaid, Michal Hocek, Thomas E Spratt, Joachim W Engels, Richard Cosstick, Robert D Kuchta Biochemistry 2007 pols set
Involvement of phage phi29 DNA polymerase and terminal protein subdomains in conferring specificity during initiation of protein-primed DNA replication. Patricia Pérez-Arnaiz, Elisa Longás, Laurentino Villar, José María Lázaro, Margarita Salas, Miguel de Vega Nucleic acids research 2007 pols set
Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains. Maria Letizia Barreca, Angela Rao, Laura De Luca, Nunzio Iraci, Anna-Maria Monforte, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Jan Balzarini, Alba Chimirri Bioorganic & medicinal chemistry letters 2007 pols set
Construction of saccharide-modified DNAs by DNA polymerase. Masayuki Matsui, Yoshitaka Nishiyama, Shin-ichi Ueji, Yasuhito Ebara Bioorganic & medicinal chemistry letters 2007 new
Yeast DNA polymerase epsilon participates in leading-strand DNA replication. Zachary F Pursell, Isabelle Isoz, Else-Britt Lundström, Erik Johansson, Thomas A Kunkel Science 2007 pols set
7-Oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamides: synthesis and biological activity of a new class of highly potent inhibitors of human cytomegalovirus DNA polymerase. Scott D Larsen, Zhijun Zhang, Brian A DiPaolo, Peter R Manninen, Douglas C Rohrer, Michael J Hageman, Todd A Hopkins, Mary L Knechtel, Nancee L Oien, Bob D Rush, Francis J Schwende, Kevin J Stefanski, Janet L Wieber, Karen F Wilkinson, Kathyrn M Zamora, Michael W Wathen, Roger J Brideau Bioorganic & medicinal chemistry letters 2007 pols set
DNA polymerase recognition of 2'-deoxy-2'-fluoroarabinonucleoside 5'-triphosphates (2'F-araNTPs). Chang G Peng, Masad J Damha Nucleosides, nucleotides & nucleic acids 2007 new
Ornithine transport via cationic amino acid transporter-1 is involved in ornithine cytotoxicity in retinal pigment epithelial cells. Shiho Kaneko, Akira Ando, Emiko Okuda-Ashitaka, Masahide Maeda, Kyoji Furuta, Motoshi Suzuki, Miyo Matsumura, Seiji Ito Investigative ophthalmology & visual science 2007 new
Quantitative measurement of telomerase reverse transcriptase, thyroglobulin and thyroid transcription factor 1 mRNAs in anaplastic thyroid carcinoma tissues and cell lines. Toru Takano, Yasuhiro Ito, Fumio Matsuzuka, Akihiro Miya, Kaoru Kobayashi, Hiroshi Yoshida, Akira Miyauchi Oncology reports 2007 new
Species-specific, P450- and sulfotransferase-mediated novel ring contraction of a naphthyridine-N-oxide compound in cynomolgus monkey. J Scott Daniels, Robert Espina, Kevin Cao, Haodan Yuan, Jianrong Lin, Sharon Diamond, Barry Johnson, James Rodgers, Shimoga Prakash, Steve Unger, David Christ, Gerald Miwa, Liang-Shang Gan, Abdul Mutlib Chemical research in toxicology 2007 pols set
Novel antiproliferative analogs of the Taq DNA polymerase inhibitor catalpol. Carlos Rodolfo Pungitore, Leticia G León, Celina García, Víctor S Martín, Carlos E Tonn, José M Padrón Bioorganic & medicinal chemistry letters 2007 pols set
Activity against human immunodeficiency virus type 1, intracellular metabolism, and effects on human DNA polymerases of 4'-ethynyl-2-fluoro-2'-deoxyadenosine. Hirotomo Nakata, Masayuki Amano, Yasuhiro Koh, Eiichi N Kodama, Guangwei Yang, Christopher M Bailey, Satoru Kohgo, Hiroyuki Hayakawa, Masao Matsuoka, Karen S Anderson, Yung-Chi Cheng, Hiroyuki Mitsuya Antimicrob Agents Chemother 2007 pols set
Effects of accessory proteins on the bypass of a cis-syn thymine-thymine dimer by Saccharomyces cerevisiae DNA polymerase eta. Scott D McCulloch, Adam Wood, Parie Garg, Peter M J Burgers, Thomas A Kunkel Biochemistry 2007 pols set
Mutations that decrease DNA binding of the processivity factor of the herpes simplex virus DNA polymerase reduce viral yield, alter the kinetics of viral DNA replication, and decrease the fidelity of DNA replication. Changying Jiang, Ying T Hwang, John C W Randell, Donald M Coen, Charles B C Hwang J Virol 2007 new
Molecular analysis of DNA polymerase eta gene in Japanese patients diagnosed as xeroderma pigmentosum variant type. Miki Tanioka, Taro Masaki, Ryusuke Ono, Tohru Nagano, Eriko Otoshi-Honda, Yasuhiro Matsumura, Masahiro Takigawa, Hiroki Inui, Yoshiki Miyachi, Shinichi Moriwaki, Chikako Nishigori J Invest Dermatol 2007 new
Slow-, tight-binding HIV-1 reverse transcriptase non-nucleoside inhibitors highly active against drug-resistant mutants. Reynel Cancio, Antonello Mai, Dante Rotili, Marino Artico, Gianluca Sbardella, Imma Clotet-Codina, José A Esté, Emmanuele Crespan, Samantha Zanoli, Ulrich Hübscher, Silvio Spadari, Giovanni Maga ChemMedChem 2007 pols set
The pyrophosphate analogue foscarnet traps the pre-translocational state of HIV-1 reverse transcriptase in a Brownian ratchet model of polymerase translocation. Bruno Marchand, Egor P Tchesnokov, Matthias Götte The Journal of biological chemistry 2007 partial results
N2-benzyloxycarbonylguan-9-yl acetic acid derivatives as HIV-1 reverse transcriptase non-nucleoside inhibitors with decreased loss of potency against common drug-resistance mutations. Kassim F Adebambo, Samantha Zanoli, Michael G Thomas, Reynel Cancio, Nicola M Howarth, Giovanni Maga ChemMedChem 2007 pols set
Ability of polymerase eta and T7 DNA polymerase to bypass bulge structures. Vincent J Cannistraro, John-Stephen Taylor The Journal of biological chemistry 2007 pols set
Sequence-specific detection of individual DNA polymerase complexes in real time using a nanopore. Seico Benner, Roger J A Chen, Noah A Wilson, Robin Abu-Shumays, Nicholas Hurt, Kate R Lieberman, David W Deamer, William B Dunbar, Mark Akeson Nat Nanotechnol 2007 complete Kate R Lieberman*
Efficient silencing of the gene coding for the epsilon subunit of DNA polymerase III in Escherichia coli is triggered by antisense RNAs featuring stability in vivo. Alessandra Stefan, Martin Tabler, Alejandro Hochkoeppler FEMS Microbiol Lett 2007 complete Alejandro Hochkoeppler*
Escherichia coli DNA polymerase IV contributes to spontaneous mutagenesis at coding sequences but not microsatellite alleles. Kimberly D Jacob, Kristin A Eckert Mutation research 2007 pols set
A quantum mechanical investigation of possible mechanisms for the nucleotidyl transfer reaction catalyzed by DNA polymerase beta. Mihaela D Bojin, Tamar Schlick J Phys Chem B 2007 new
Lesion bypass activity of DNA polymerase A from the extremely radioresistant organism Deinococcus radiodurans. Kathrin Heinz, Andreas Marx The Journal of biological chemistry 2007 new
Interaction of the family-B DNA polymerase from the archaeon Pyrococcus furiosus with deaminated bases. Sukhvinder Gill, Rory O'Neill, Richard J Lewis, Bernard A Connolly Journal of molecular biology 2007 partial results
Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerases. Christian Castro, Eric D Smidansky, Kenneth R Maksimchuk, Jamie J Arnold, Victoria S Korneeva, Matthias Götte, William H Konigsberg, Craig E Cameron Proceedings of the National Academy of Sciences of the United States of America 2007 complete
Aprataxin, causative gene product for EAOH/AOA1, repairs DNA single-strand breaks with damaged 3'-phosphate and 3'-phosphoglycolate ends. Tomosaburo Takahashi, Masayoshi Tada, Shuichi Igarashi, Akihide Koyama, Hidetoshi Date, Akio Yokoseki, Atsushi Shiga, Yutaka Yoshida, Shoji Tsuji, Masatoyo Nishizawa, Osamu Onodera Nucleic acids research 2007 new
Expanding the repertoire of DNA polymerase substrates: template-instructed incorporation of non-nucleoside triphosphate analogues by DNA polymerases beta and lambda. Emmanuele Crespan, Ludmila Alexandrova, Anastasiya Khandazhinskaya, Maxim Jasko, Marina Kukhanova, Giuseppe Villani, Ulrich Hübscher, Silvio Spadari, Giovanni Maga Nucleic acids research 2007 new
Specific terminal labeling of DNA molecules. Yasushi Shigemori, Michio Oishi BioTechniques 2007 topics set
[Complex of repair DNA polymerase beta with autonomous 3'-->5'-exonuclease shows increased accuracy of DNA synthesis]. N V Beliakova, T P Kravetskaia, O K Legina, N L Ronzhina, Igor V Shevelev, V M Krutiakov Izv Akad Nauk Ser Biol 2007 new
Molecular breeding of polymerases for amplification of ancient DNA. Marc d'Abbadie, Michael Hofreiter, Alexandra Vaisman, David Loakes, Didier Gasparutto, Jean Cadet, Roger Woodgate, Svante Pääbo, Philipp Holliger Nature biotechnology 2007 pols set
Evidence that in xeroderma pigmentosum variant cells, which lack DNA polymerase eta, DNA polymerase iota causes the very high frequency and unique spectrum of UV-induced mutations. Yun Wang, Roger Woodgate, Terrence P McManus, Samantha Mead, J Justin McCormick, Veronica M Maher Cancer research 2007 new
A simple screening approach to reduce B*5701-associated abacavir hypersensitivity on the basis of sequence variation in HIV reverse transcriptase. Celia K S Chui, Zabrina L Brumme, Chanson J Brumme, Benita Yip, Elizabeth J Phillips, Julio S G Montaner, P Richard Harrigan Clin Infect Dis 2007 new
Modifying the beta,gamma leaving-group bridging oxygen alters nucleotide incorporation efficiency, fidelity, and the catalytic mechanism of DNA polymerase beta. Christopher A Sucato, Thomas G Upton, Boris A Kashemirov, Vinod K Batra, Václav Martínek, Yun Xiang, William A Beard, Lars C Pedersen, Samuel H Wilson, Charles E McKenna, Jan Florián, Arieh Warshel, Myron F Goodman Biochemistry 2007 topics set
The EM structure of human DNA polymerase gamma reveals a localized contact between the catalytic and accessory subunits. Elena Yakubovskaya, Mark Lukin, Zhixin Chen, John Berriman, Joseph S Wall, Ryuji Kobayashi, Caroline Kisker, Daniel F Bogenhagen The EMBO journal 2007 pols set
MutS deficiency and activity of the error-prone DNA polymerase IV are crucial for determining mucA as the main target for mucoid conversion in Pseudomonas aeruginosa. Alejandro J Moyano, Adela M Luján, Carlos E Argaraña, Andrea M Smania Molecular microbiology 2007 pols set
Complex formation of yeast Rev1 with DNA polymerase eta. Narottam Acharya, Lajos Haracska, Satya Prakash, Louise Prakash Molecular and cellular biology 2007 new
Distinct energetics and closing pathways for DNA polymerase beta with 8-oxoG template and different incoming nucleotides. Yazhen Wang, Tamar Schlick BMC Struct Biol 2007 new
Mechanism of abasic lesion bypass catalyzed by a Y-family DNA polymerase. Kevin A Fiala, Cameron D Hypes, Zucai Suo The Journal of biological chemistry 2007 topics set
Investigating the "steric gate" of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase by targeted insertion of unnatural amino acids. George J Klarmann, Brian M Eisenhauer, Yongqing Zhang, Matthias Gotte, Janice D Pata, Deb K Chatterjee, Sidney M Hecht, Stuart F J Le Grice Biochemistry 2007 pols set
Regulation of B family DNA polymerase fidelity by a conserved active site residue: characterization of M644W, M644L and M644F mutants of yeast DNA polymerase epsilon. Zachary F Pursell, Isabelle Isoz, Else-Britt Lundström, Erik Johansson, Thomas A Kunkel Nucleic acids research 2007 new
Should we include connection domain mutations of HIV-1 reverse transcriptase in HIV resistance testing. Matthias Götte PLoS medicine 2007 pols set
Solution structure of Domains IVa and V of the tau subunit of Escherichia coli DNA polymerase III and interaction with the alpha subunit. Xun-Cheng Su, Slobodan Jergic, Max A Keniry, Nicholas E Dixon, Gottfried Otting Nucleic acids research 2007 topics set
Replisome mechanics: insights into a twin DNA polymerase machine. Richard T Pomerantz, Mike E O'Donnell Trends Microbiol 2007 new
Conformational dynamics of DNA polymerase probed with a novel fluorescent DNA base analogue. Gudrun Stengel, JP Gill, Peter Sandin, L Marcus Wilhelmsson, Bo Albinsson, Bengt Nordén, David P Millar Biochemistry 2007 topics set
Enzymatic therapeutic index of acyclovir. Viral versus human polymerase gamma specificity. Jeremiah W Hanes, Yali Zhu, Deborah S Parris, Kenneth A Johnson The Journal of biological chemistry 2007 new
Caught bending the A-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide. Karl E Zahn, Hassan Belrhali, Susan S Wallace, Sylvie Doublié Biochemistry 2007 topics set
N.BspD6I DNA nickase strongly stimulates template-independent synthesis of non-palindromic repetitive DNA by Bst DNA polymerase. Nadezhda V Zyrina, Lyudmila A Zheleznaya, Eugene V Dvoretsky, Victor D Vasiliev, Andrei Chernov, Nicholas I Matvienko Biol Chem 2007 pols set
Fidelity and processivity of reverse transcription by the human mitochondrial DNA polymerase. Harold R Lee, Kenneth A Johnson The Journal of biological chemistry 2007 pols set
DNA polymerase beta catalysis: are different mechanisms possible? Ian L Alberts, Yazhen Wang, Tamar Schlick Journal of the American Chemical Society 2007 new
Ionizing radiation sensitivity of DNA polymerase lambda-deficient cells. Christie Vermeulen, Barbara Bertocci, Adrian C Begg, Conchita Vens Radiat Res 2007 new
Highly selective action of triphosphate metabolite of 4'-ethynyl D4T: a novel anti-HIV compound against HIV-1 RT. Guangwei Yang, Ginger E Dutschman, Chuan-Jen Wang, Hiromichi Tanaka, Masanori Baba, Karen S Anderson, Yung-Chi Cheng Antiviral Res 2007 new
A novel mechanism of selectivity against AZT by the human mitochondrial DNA polymerase. Jeremiah W Hanes, Kenneth A Johnson Nucleic acids research 2007 new
Multiple oxidative phosphorylation deficiencies in severe childhood multi-system disorders due to polymerase gamma (POLG1) mutations. Maaike C de Vries, Richard J Rodenburg, Eva Morava, Edwin P M van Kaauwen, Henk ter Laak, Reinier A Mullaart, Irina N Snoeck, Peter M van Hasselt, Peter Harding, Lambert P W van den Heuvel, Jan A M Smeitink European journal of pediatrics 2007 pols set
Hydrogen bonding of 7,8-dihydro-8-oxodeoxyguanosine with a charged residue in the little finger domain determines miscoding events in Sulfolobus solfataricus DNA polymerase Dpo4. Robert Lawton Eoff, Adriana Irimia, Karen C Angel, Martin Egli, F Peter Guengerich The Journal of biological chemistry 2007 topics set
Nitroimidazoles Part 6. Synthesis, structure and in vitro anti-HIV activity of new 5-substituted piperazinyl-4-nitroimidazole derivatives. Najim A Al-Masoudi, Yaseen A Al-Soud, Erik De Clercq, Christophe Pannecouque Antiviral chemistry & chemotherapy 2007 new
N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance. Soo-Huey Yap, Chih-Wei Sheen, Jonathan Fahey, Mark Zanin, David Tyssen, Viviane Dias Lima, Brian Wynhoven, Michael Kuiper, Nicolas Sluis-Cremer, P Richard Harrigan, Gilda Tachedjian PLoS Med 2007 partial results
Elongation of palindromic repetitive DNA by DNA polymerase from hyperthermophilic archaea: a mechanism of DNA elongation and diversification. Norio Ogata Biochimie 2007 complete Norio Ogata*
Mutation of the linker region of the polymerase gamma-1 (POLG1) gene associated with progressive external ophthalmoplegia and Parkinsonism. Gavin Hudson, Andrew M Schaefer, Robert W Taylor, Watcharee Tiangyou, Andrew Gibson, Graham Venables, Philip Griffiths, David J Burn, Douglass M Turnbull, Patrick F Chinnery Archives of neurology 2007 pols set
Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates. Andrew J Low, Winnie W Y Dong, Dennison Chan, Tobias Sing, Ronald Swanstrom, Mark Jensen, Satish Pillai, Benjamin Good, P Richard Harrigan Aids 2007 new
Mutational patterns associated with the 69 insertion complex in multi-drug-resistant HIV-1 reverse transcriptase that confer increased excision activity and high-level resistance to zidovudine. Clara E Cases-González, Sandra Franco, Miguel Angel Martínez, L Menéndez-Arias Journal of molecular biology 2007 topics set
Novel mutation of human DNA polymerase gamma associated with mitochondrial toxicity induced by anti-HIV treatment. Hikaru Yamanaka, Hiroyuki Gatanaga, Pope Kosalaraksa, Saori Matsuoka-Aizawa, Tomonori Takahashi, Seisuke Kimura, Shinichi Oka J Infect Dis 2007 pols set
Decreased mtDNA, oxidative stress, cardiomyopathy, and death from transgenic cardiac targeted human mutant polymerase gamma. William Lewis, Brian J Day, James J Kohler, Seyed H Hosseini, Sherine S L Chan, Elgin C Green, Chad P Haase, Erin S Keebaugh, Robert Long, Tomika Ludaway, Rodney Russ, Jeffrey Steltzer, Nina Tioleco, Robert Santoianni, William C Copeland Laboratory investigation; a journal of technical methods and pathology 2007 pols set
MELAS associated with mutations in the POLG1 gene. M Deschauer, S Tennant, A Rokicka, L He, T Kraya, Douglass M Turnbull, S Zierz, Robert W Taylor Neurology 2007 pols set
Structure of the RNA-binding domain of telomerase: implications for RNA recognition and binding. Susan Rouda, Emmanuel Skordalakes Structure (London, England : 1993) 2007 complete Emmanuel Skordalakes*
Structure of the ubiquitin-binding zinc finger domain of human DNA Y-polymerase eta. Martha G Bomar, Ming-Tao Pai, Shiou-Ru Tzeng, Shawn Shun-Cheng Li, Pei Zhou EMBO Rep 2007 complete Pei Zhou*
Reevaluating the capability of Taq DNA polymerase: long PCR amplification. Hayan Lee, Kyung-Nam Kim, Young Kee Chae Protein Pept Lett 2007 pols set
Role for DNA polymerase beta in response to ionizing radiation. Christie Vermeulen, Manon Verwijs-Janssen, Patricia Cramers, Adrian C Begg, Conchita Vens DNA repair 2007 new
Human DNA polymerase lambda is a proficient extender of primer ends paired to 7,8-dihydro-8-oxoguanine. Angel J Picher, Luis Blanco DNA repair 2007 pols set
Ischemic preconditioning induces XRCC1, DNA polymerase-beta, and DNA ligase III and correlates with enhanced base excision repair. Ning Li, Hao Wu, Sufang Yang, Dexi Chen DNA repair 2007 new
Possible role of DNA polymerase beta in protecting human bronchial epithelial cells against cytotoxicity of hydroquinone. Da-Lin Hu, Huan-Wen Tang, Hai-Rong Liang, Dong-Sheng Tang, Yi-Ming Liu, Wei-Dong Ji, Jian-Hui Yuan, Yun He, Zheng-Yu Zhu, Jian-Ping Yang, Dao-Kui Fang, Yan Sha, Xiao-Zhi Tu, Zhi-Xiong Zhuang Biomed Environ Sci 2007 new
Role of the catalytic metal during polymerization by DNA polymerase lambda. Miguel Garcia-Diaz, Katarzyna Bebenek, Joseph M Krahn, Lars C Pedersen, Thomas A Kunkel DNA repair 2007 topics set
Replication of 2-hydroxyadenine-containing DNA and recognition by human MutSalpha. Flavia Barone, Scott D McCulloch, Peter Macpherson, Giovanni Maga, Masami Yamada, Takehiko Nohmi, Anna Minoprio, Filomena Mazzei, Thomas A Kunkel, Peter Karran, Margherita Bignami DNA repair 2007 topics set
The X family portrait: structural insights into biological functions of X family polymerases. Andrea F Moon, Miguel Garcia-Diaz, Vinod K Batra, William A Beard, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson, Lars C Pedersen DNA repair 2007 topics set
Development and validation of a non-radioactive DNA polymerase assay for studying cytomegalovirus resistance to foscarnet. Alexandra Ducancelle, Sophie Alain, Françoise Petit, Marie-José Sanson Le Pors, Marie-Christine Mazeron J Virol Methods 2007 new
Transmission of drug-resistant HIV-1 from an infected individual to a caregiver. Chanson J Brumme, P Richard Harrigan, Emma C Preston, Winnie W Y Dong, Brian Wynhoven, Carol Murphy, Julio S G Montaner Antivir Ther 2007 new
Determinants of nevirapine hypersensitivity and its effect on the association between hepatitis C status and mortality in antiretroviral drug-naive HIV-positive patients. Elizabeth J Phillips, Sonia Gutiérrez, Natalie Jahnke, Benita Yip, Viviane Dias Lima, Robert S Hogg, P Richard Harrigan, Julio S G Montaner Aids 2007 new
p53 suppression overwhelms DNA polymerase eta deficiency in determining the cellular UV DNA damage response. Rebecca R Laposa, Luzviminda Feeney, Eileen Crowley, Sebastien de Feraudy, James E Cleaver DNA repair 2007 new
Solution structure of polymerase mu's BRCT Domain reveals an element essential for its role in nonhomologous end joining. Eugene F DeRose, Michael W Clarkson, Steven A Gilmore, Cristina J Galban, Ashutosh Tripathy, Jody M Havener, Geoffrey A Mueller, Dale A Ramsden, Robert E London, Andrew L Lee Biochemistry 2007 topics set
Duplex strand joining reactions catalyzed by vaccinia virus DNA polymerase. Michael D Hamilton, Anthony A Nuara, Don B Gammon, R Mark Buller, David H Evans Nucleic acids research 2007 complete David H Evans*
Optimization of non-natural nucleotides for selective incorporation opposite damaged DNA. Diana Vineyard, Xuemei Zhang, Alison Donnelly, Irene Lee, Anthony J Berdis Org Biomol Chem 2007 topics set
Mutations in the ubiquitin binding UBZ motif of DNA polymerase eta do not impair its function in translesion synthesis during replication. Narottam Acharya, Amrita Brahma, Lajos Haracska, Louise Prakash, Satya Prakash Molecular and cellular biology 2007 topics set
In vitro fidelity of the prototype primate foamy virus (PFV) RT compared to HIV-1 RT. Paul L Boyer, Carolyn R Stenbak, David Hoberman, Maxine L Linial, Stephen H Hughes Virology 2007 partial results
Crosslinking of the NER damage recognition proteins XPC-HR23B, XPA and RPA to photoreactive probes that mimic DNA damages. Ekaterina A Maltseva, Nadejda I Rechkunova, Ludovic C Gillet, Irina O Petruseva, Orlando D Schärer, Olga I Lavrik Biochimica et biophysica acta 2007 new
Upregulation of error-prone DNA polymerases beta and kappa slows down fork progression without activating the replication checkpoint. Marie-Jeanne Pillaire, Rémy Betous, Chiara Conti, Jerzy Czaplicki, Philippe Pasero, Aaron Bensimon, Christophe Cazaux, Jean-Sébastien Hoffmann Cell Cycle 2007 new
Immortalization of swine umbilical vein endothelial cells with human telomerase reverse transcriptase. Hai Xia Hong, Yan Ming Zhang, Hao Xu, Zheng Yuan Su, Pei Sun Molecules and cells 2007 new
Hydrophobic amino acid and single-atom substitutions increase DNA polymerase selectivity. Nicolas Z Rudinger, Ramon Kranaster, Andreas Marx Chemistry & biology 2007 complete Andreas Marx*
A function for the psi subunit in loading the Escherichia coli DNA polymerase sliding clamp. Stephen G Anderson, Christopher R Williams, Mike E O'Donnell, Linda B Bloom The Journal of biological chemistry 2007 pols set
Effect and mechanism of beta-L-D4A on DNA polymerase alpha. Yan Li, Ju-Sheng Lin, Ying-Hui Zhang, Xiao-Yan Wang, Ying Chang, Xing-Xing He World journal of gastroenterology : WJG 2007 new
Replisome fate upon encountering a leading strand block and clearance from DNA by recombination proteins. Peter McInerney, Mike E O'Donnell The Journal of biological chemistry 2007 topics set
Diminished efficiency of HIV-1 reverse transcriptase containing the K65R and M184V drug resistance mutations. Fernando A Frankel, Cédric F Invernizzi, Maureen Oliveira, Mark A. Wainberg AIDS (London, England) 2007 pols set
Mechanisms of resistance associated with excision of incorporated nucleotide analogue inhibitors of HIV-1 reverse transcriptase. Matthias Götte Current opinion in HIV and AIDS 2007 pols set
Mitochondrial DNA depletion is a prevalent cause of multiple respiratory chain deficiency in childhood. Emmanuelle Sarzi, Alice Bourdon, Dominique Chrétien, Mohamed Zarhrate, Johanna Corcos, Abdelhamid Slama, Valérie Cormier-Daire, Pascale de Lonlay, Arnold Munnich, Agnès Rötig The Journal of pediatrics 2007 pols set
HMGB1 is a cofactor in mammalian base excision repair. Rajendra Prasad, Yuan Liu, Leesa J Deterding, Vladimir P Poltoratsky, Padmini S Kedar, Julie K Horton, Shin-Ichiro Kanno, Kenjiro Asagoshi, Esther W Hou, Svetlana N Khodyreva, Olga I Lavrik, Kenneth B Tomer, Akira Yasui, Samuel H Wilson Molecular cell 2007 new
Structure and function of a mycobacterial NHEJ DNA repair polymerase. Robert S Pitcher, Nigel C Brissett, Angel J Picher, Paula Andrade, Raquel Juarez, Darren Thompson, Gavin C Fox, Luis Blanco, Aidan J Doherty Journal of molecular biology 2007 partial results
Therapeutic strategies towards HIV-1 infection in macrophages. CF Perno, Valentina Svicher, Dominique Schols, Michela Pollicita, Jan Balzarini, Stefano Aquaro Antiviral research 2006 pols set
RecA acts in trans to allow replication of damaged DNA by DNA polymerase V. Katharina Schlacher, Michael M Cox, Roger Woodgate, Myron F Goodman Nature 2006 new
Visualization of the interaction between archaeal DNA polymerase and uracil-containing DNA by atomic force microscopy. Yasuo Asami, Masahiro Murakami, Masatomi Shimizu, Francesca M Pisani, Isamu Hayata, Takehiko Nohmi Genes Cells 2006 new
Effects of drug resistance on viral load in patients failing antiretroviral therapy. N Machouf, R Thomas, V K Nguyen, B Trottier, M R Boulassel, Mark A. Wainberg, Jean-Pierre Routy Journal of medical virology 2006 pols set
Interactions of carcinogen-bound DNA with individual DNA polymerases. F Peter Guengerich Chem Rev 2006 topics set
Evolving thermostable reverse transcriptase activity in a DNA polymerase scaffold. Katharina B M Sauter, Andreas Marx Angewandte Chemie (International ed. in English) 2006 new
Accumulation of FFA-1, the Xenopus homolog of Werner helicase, and DNA polymerase delta on chromatin in response to replication fork arrest. Noriko Sasakawa, Tomoyuki Fukui, Shou Waga J Biochem 2006 new
Mechanism of nucleotide incorporation in DNA polymerase beta. Ravi Radhakrishnan Biochem Biophys Res Commun 2006 topics set
Biochemical basis of genotoxicity of heterocyclic arylamine food mutagens: Human DNA polymerase eta selectively produces a two-base deletion in copying the N2-guanyl adduct of 2-amino-3-methylimidazo[4,5-f]quinoline but not the C8 adduct at the NarI G3 site. Jeong-Yun Choi, James S Stover, Karen C Angel, Goutam Chowdhury, Carmelo J Rizzo, F Peter Guengerich The Journal of biological chemistry 2006 pols set
The properties of steric gate mutants reveal different constraints within the active sites of Y-family and A-family DNA polymerases. Angela M DeLucia, Santanov Chaudhuri, Olga Potapova, Nigel D F Grindley, Catherine M Joyce The Journal of biological chemistry 2006 new
Adenovirus mediated transduction of the human DNA polymerase eta cDNA. Keronninn Moreno Lima-Bessa, Vanessa Chiganças, Anne Stary, Patricia L Kannouche, Alain Sarasin, Melissa Gava Armelini, Jacqueline de Fátima Jacysyn, Gustavo P Amarante-Mendes, Marila Cordeiro-Stone, James E Cleaver, Carlos Frederico Martins Menck DNA repair 2006 complete Carlos Frederico Martins Menck*
Multiplexed DNA sequencing-by-synthesis. Sergei A Aksyonov, Michael Bittner, Linda B Bloom, Linda J Reha-Krantz, Ian R Gould, Mark A Hayes, Urban A Kiernan, Eric E Niederkofler, Vincent Pizziconi, Raul S Rivera, Daniel J B Williams, Peter Williams Anal Biochem 2006 complete
Inhibitory effect of coenzyme Q on eukaryotic DNA polymerase gamma and DNA topoisomerase II activities on the growth of a human cancer cell line. Yuko Yonezawa, Isoko Kuriyama, Atsushi Fukuoh, Tsuyoshi Muta, Dongchon Kang, Masaharu Takemura, Ikunoshin Kato, Hiromi Yoshida, Yoshiyuki Mizushina Cancer Sci 2006 pols set
Isolation of human Dna2 endonuclease and characterization of its enzymatic properties. Jeong-Hoon Kim, Hee-Dai Kim, Gi-Hyuck Ryu, Do-Hyung Kim, Jerard Hurwitz, Yeon-Soo Seo Nucleic acids research 2006 complete Yeon-Soo Seo*
Measuring the fidelity of translesion DNA synthesis. Scott D McCulloch, Thomas A Kunkel Methods in enzymology 2006 pols set
Coexpression of the subunits of T7 DNA polymerase from an artificial operon allows one-step purification of active gp5/Trx complex. Joyce Chiu, Daniel Tillett, Paul E March Protein Expr Purif 2006 pols set
Effect of molecular crowding on DNA polymerase activity. Yoshiharu Sasaki, Daisuke Miyoshi, Naoki Sugimoto Biotechnol J 2006 new
Human cytomegalovirus DNA polymerase catalytic subunit pUL54 possesses independently acting nuclear localization and ppUL44 binding motifs. Gualtiero Alvisi, Alessandro Ripalti, Apollinaire Ngankeu, Maila Giannandrea, Stefano G Caraffi, Manisha M Dias, David A Jans Traffic 2006 pols set
RNA aptamers selected against DNA polymerase beta inhibit the polymerase activities of DNA polymerases beta and kappa. Leonid V Gening, Svetlana A Klincheva, Anastasia Reshetnjak, Arthur P Grollman, Holly Miller Nucleic acids research 2006 new
Early detection and quantification of lamivudine-resistant hepatitis B virus mutants by fluorescent biprobe hybridization assay in lamivudine-treated patients. Fumi Umeoka, Yoshiaki Iwasaki, Masayuki Matsumura, Akinobu Takaki, Haruhiko Kobashi, Masashi Tatsukawa, Hidenori Shiraha, Shin-ichi Fujioka, Kohsaku Sakaguchi, Yasushi Shiratori Journal of gastroenterology 2006 new
Synergistic antiviral activity of acyclovir and vidarabine against herpes simplex virus types 1 and 2 and varicella-zoster virus. Mikiko Suzuki, Tomoko Okuda, Kimiyasu Shiraki Antiviral research 2006 new
Structural determinants of slippage-mediated mutations by human immunodeficiency virus type 1 reverse transcriptase. Monica E Hamburgh, Kenneth A Curr, Melissa Monaghan, Vasudev R Rao, Snehlata Tripathi, Bradley D Preston, Stefan G Sarafianos, Edward Arnold, Thomas Darden, Vinayaka R Prasad The Journal of biological chemistry 2006 pols set
DNA polymerase iota-dependent translesion replication of uracil containing cyclobutane pyrimidine dimers. Alexandra Vaisman, Kohei Takasawa, Shigenori Iwai, Roger Woodgate DNA repair 2006 new
Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus. Sherwin P Montaño, Marie L Coté, Monica J Roth, Millie M Georgiadis Nucleic acids research 2006 topics set
Single-molecule investigation of the T4 bacteriophage DNA polymerase holoenzyme: multiple pathways of holoenzyme formation. R Derike Smiley, Zhihao Zhuang, Stephen J Benkovic, Gordon G Hammes Biochemistry 2006 topics set
Wanderings of a DNA enzymologist: from DNA polymerase to viral latency. IRobert Lehman Annual review of biochemistry 2006 new
Synthesis, DNA polymerase incorporation, and enzymatic phosphate hydrolysis of formamidopyrimidine nucleoside triphosphates. Shuhei Imoto, Jennifer N Patro, Yu Lin Jiang, Natsuhisa Oka, Marc M Greenberg Journal of the American Chemical Society 2006 pols set
Mitochondrial DNA polymerase-gamma and human disease. Gavin Hudson, Patrick F Chinnery Hum Mol Genet 2006 new
Kinetic effect of a downstream strand and its 5'-terminal moieties on single nucleotide gap-filling synthesis catalyzed by human DNA polymerase lambda. Wade W Duym, Kevin A Fiala, Nikunj Bhatt, Zucai Suo The Journal of biological chemistry 2006 pols set
The level of reverse transcriptase (RT) in human immunodeficiency virus type 1 particles affects susceptibility to nonnucleoside RT inhibitors but not to lamivudine. Zandrea Ambrose, John G Julias, Paul L Boyer, Vineet N Kewalramani, Stephen H Hughes Journal of virology 2006 pols set
Enhanced expression and activity of DNA polymerase beta in chronic myelogenous leukemia. Yvan Canitrot, Guy Laurent, Catherine Astarie-Dequeker, Christine Bordier, Christophe Cazaux, Jean-Sébastien Hoffmann Anticancer Res 2006 new
Bioactive isomalabaricane triterpenoids from Rhabdastrella globostellata that stabilize the binding of DNA polymerase beta to DNA. Jason A Clement, Mei Li, Sidney M Hecht, David G I Kingston J Nat Prod 2006 new
Site-directed mutations of T4 helicase loading protein (gp59) reveal multiple modes of DNA polymerase inhibition and the mechanism of unlocking by gp41 helicase. Scott W Nelson, Jingsong Yang, Stephen J Benkovic The Journal of biological chemistry 2006 new
Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): modeling and dynamics studies. Ling Zhang, Olga Rechkoblit, Liming Wang, Dinshaw J Patel, Robert Shapiro, Suse Broyde Nucleic acids research 2006 topics set
Structure of purine-purine mispairs during misincorporation and extension by Escherichia coli DNA polymerase I. Angie M Kretulskie, Thomas E Spratt Biochemistry 2006 pols set
Visualizing polynucleotide polymerase machines at work. Thomas A Steitz The EMBO journal 2006 pols set
Rational attempts to optimize non-natural nucleotides for selective incorporation opposite an abasic site. Xuemei Zhang, Alison Donnelly, Irene Lee, Anthony J Berdis Biochemistry 2006 topics set
Correct and incorrect nucleotide incorporation pathways in DNA polymerase beta. Ravi Radhakrishnan, Tamar Schlick Biochem Biophys Res Commun 2006 topics set
Estimation of DNA polymerase for improvement of rolling circle amplification. Takeo Yoshimura, Saori Arikado, Shokichi Ohuchi Nucleic Acids Symp Ser (Oxf) 2006 new
Fluorescent analysis of translesion DNA synthesis by using a novel, non-natural nucleotide analogue. Irene Lee, Anthony J Berdis Chembiochem : a European journal of chemical biology 2006 topics set
Ankyrin G overexpression in Hutchinson-Gilford progeria syndrome fibroblasts identified through biological filtering of expression profiles. Jian Wang, John F Robinson, Caroline H O'Neil, Jane Y Edwards, Christina M Williams, Murray W Huff, J Geoffrey Pickering, Robert A Hegele Journal of human genetics 2006 new
Preliminary characterization of a thermostable DNA polymerase I from a mesophilic Bacillus sphaericus strain C3-41. Han Bei, Liu Haizhou, Hu Xiaomin, Yuan Zhiming Arch Microbiol 2006 new
The C-terminal residues of bacteriophage T7 gene 4 helicase-primase coordinate helicase and DNA polymerase activities. Seung-Joo Lee, Boriana Marintcheva, Samir M Hamdan, Charles C Richardson The Journal of biological chemistry 2006 pols set
Remarkable sensitivity to DNA base shape in the DNA polymerase active site. Herman O Sintim, Eric T Kool Angew Chem Int Ed Engl 2006 new
Involvement of phi29 DNA polymerase thumb subdomain in the proper coordination of synthesis and degradation during DNA replication. Patricia Pérez-Arnaiz, José María Lázaro, Margarita Salas, Miguel de Vega Nucleic acids research 2006 pols set
Mutant POLG2 disrupts DNA polymerase gamma subunits and causes progressive external ophthalmoplegia. Matthew J Longley, Susanna Clark, Cynthia Yu Wai Man, Gavin Hudson, Steve E Durham, Robert W Taylor, Simon Nightingale, Douglass M Turnbull, William C Copeland, Patrick F Chinnery Am J Hum Genet 2006 new
Characterization and application of aptamers for Taq DNA polymerase selected using an evolution-mimicking algorithm. Takahisa Noma, Koji Sode, Kazunori Ikebukuro Biotechnol Lett 2006 pols set
Essential residues in the C terminus of the bacteriophage T7 gene 2.5 single-stranded DNA-binding protein. Boriana Marintcheva, Samir M Hamdan, Seung-Joo Lee, Charles C Richardson The Journal of biological chemistry 2006 pols set
Deficiency of the Caenorhabditis elegans DNA polymerase eta homologue increases sensitivity to UV radiation during germ-line development. Tsuyoshi Ohkumo, Chikahide Masutani, Toshihiko Eki, Fumio Hanaoka Cell Struct Funct 2006 new
Sequential side-chain residue motions transform the binary into the ternary state of DNA polymerase lambda. Meredith C Foley, Karunesh Arora, Tamar Schlick Biophys J 2006 new
Double-stranded DNA binding, an unusual property of DNA polymerase epsilon, promotes epigenetic silencing in Saccharomyces cerevisiae. Toshiaki Tsubota, Rie Tajima, Kunitomo Ode, Hajime Kubota, Naoshi Fukuhara, Takeshi Kawabata, Satoko Maki, Hisaji Maki The Journal of biological chemistry 2006 pols set
A mass spectrometry-based approach for identifying novel DNA polymerase substrates from a pool of dNTP analogues. Kristi Kincaid, Robert D Kuchta Nucleic acids research 2006 new
Localization of Y-family polymerases and the DNA polymerase switch in mammalian cells. Patricia L Kannouche, Alan R Lehmann Methods in enzymology 2006 new
DNA primase acts as a molecular brake in DNA replication. Jong-Bong Lee, Richard K Hite, Samir M Hamdan, X Sunney Xie, Charles C Richardson, Antoine M van Oijen Nature 2006 new
Hoogsteen base pair formation promotes synthesis opposite the 1,N6-ethenodeoxyadenosine lesion by human DNA polymerase iota. Deepak T Nair, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Nature structural & molecular biology 2006 topics set
Plasticity of the gene functions for DNA replication in the T4-like phages. Vasiliy M Petrov, James M Nolan, Claire Bertrand, Dawn Levy, Carine Desplats, H M Krisch, Jim D Karam Journal of molecular biology 2006 topics set
Mutation of Phe102 to Ser in the carboxyl terminal helix of Escherichia coli thioredoxin affects the stability and processivity of T7 DNA polymerase. Joyce Chiu, Daniel Tillett, Paul E March Proteins 2006 pols set
Crystal structure of the cytomegalovirus DNA polymerase subunit UL44 in complex with the C terminus from the catalytic subunit. Differences in structure and function relative to unliganded UL44. Brent A Appleton, Justin Brooks, Arianna Loregian, David J Filman, Donald M Coen, James M Hogle The Journal of biological chemistry 2006 topics set
Functional roles of p12, the fourth subunit of human DNA polymerase delta. Hao Li, Bin Xie, Yanjiao Zhou, Amal A Rahmeh, Sandra Trusa, Sufang Zhang, Yan Gao, Ernest Y C Lee, Marietta Y W T Lee The Journal of biological chemistry 2006 pols set
Novel thermostable Y-family polymerases: applications for the PCR amplification of damaged or ancient DNAs. John P McDonald, Ashley Hall, Didier Gasparutto, Jean Cadet, Jack Ballantyne, Roger Woodgate Nucleic acids research 2006 pols set
Hybrid antibacterials. DNA polymerase-topoisomerase inhibitors. Chengxin Zhi, Zheng-Yu Long, Andrzej Manikowski, Jeanne Comstock, Wei-Chu Xu, Neal C Brown, Paul M Tarantino, Karsten A Holm, Edward J Dix, George E Wright, Marjorie H Barnes, Michelle M Butler, Kimberly A Foster, William A LaMarr, Benoit Bachand, Richard Bethell, Caroline Cadilhac, Sylvie Charron, Serge Lamothe, Irina Motorina, Richard Storer J Med Chem 2006 new
[Association between high activity of DNA polymerase iota and the development of human uveal melanoma]. Leonid V Gening, E E Grishina, A N Petrochenkov, Vyacheslav Z Tarantul Genetika 2006 new
African swine fever virus protein pE296R is a DNA repair apurinic/apyrimidinic endonuclease required for virus growth in swine macrophages. Modesto Redrejo-Rodríguez, Ramón García-Escudero, Rafael J Yáñez-Muñoz, María L Salas, José Salas Journal of virology 2006 new
Novel nonnucleoside inhibitors that select nucleoside inhibitor resistance mutations in human immunodeficiency virus type 1 reverse transcriptase. Zhijun Zhang, Michelle Walker, Wen Xu, Jae Hoon Shim, Jean-Luc Girardet, Robert K Hamatake, Zhi Hong Antimicrobial agents and chemotherapy 2006 pols set
A method to select for mutator DNA polymerase deltas in Saccharomyces cerevisiae. Kelly M Murphy, Hariyanto Darmawan, Amy Schultz, Elizabeth Fidalgo da Silva, Linda J Reha-Krantz Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2006 new
Selective excision of chain-terminating nucleotides by HIV-1 reverse transcriptase with phosphonoformate as substrate. Carlos Cruchaga, Elena Ansó, Ana Rouzaut, Juan J Martínez-Irujo The Journal of biological chemistry 2006 new
Poleta, Polzeta and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cells. Bo Zhao, Jianhong Wang, Nicholas E Geacintov, Zhengqiang Wang Nucleic acids research 2006 topics set
Direct interaction of p21 with p50, the small subunit of human DNA polymerase delta. Hao Li, Bin Xie, Amal A Rahmeh, Yanjiao Zhou, Marietta Y W T Lee Cell Cycle 2006 pols set
Site-directed mutational analysis of structural interactions of low molecule compounds binding to the N-terminal 8 kDa domain of DNA polymerase beta. Shizuka Murakami, Shinji Kamisuki, Kei-ichi Takata, Nobuyuki Kasai, Seisuke Kimura, Yoshiyuki Mizushina, Keisuke Ohta, Fumio Sugawara, Kengo Sakaguchi Biochem Biophys Res Commun 2006 new
Identification of differently expressed genes in human colorectal adenocarcinoma. Yao Chen, Yi-Zeng Zhang, Zong-Guang Zhou, Gang Wang, Zeng-Ni Yi World journal of gastroenterology : WJG 2006 new
[The animal research of recombinant adenovirus controlled by human telomerase reverse transcriptase promoter in the treatment of human prostate cancer]. Yong Zhang, Jin-chun Qi, Wen-feng Lian, Wen-qing Cai, Wei Li, Kai-long Liu Zhonghua wai ke za zhi [Chinese journal of surgery] 2006 new
Vertebrate POLQ and POLbeta cooperate in base excision repair of oxidative DNA damage. Michio Yoshimura, Masaoki Kohzaki, Jun Nakamura, Kenjiro Asagoshi, Eiichiro Sonoda, Esther W Hou, Rajendra Prasad, Samuel H Wilson, Keizo Tano, Akira Yasui, Li Lan, Masayuki Seki, Richard D Wood, Hiroshi Arakawa, Jean-Marie Buerstedde, Helfrid Hochegger, Takashi Okada, Masahiro Hiraoka, Shunichi Takeda Molecular cell 2006 complete Shunichi Takeda*
DNA polymerase zeta accounts for the reduced cytotoxicity and enhanced mutagenicity of cisplatin in human colon carcinoma cells that have lost DNA mismatch repair. Xinjian Lin, Julie Trang, Tsuyoshi Okuda, Stephen B Howell Clin Cancer Res 2006 new
Modulation of the W748S mutation in DNA polymerase gamma by the E1143G polymorphismin mitochondrial disorders. Sherine S L Chan, Matthew J Longley, William C Copeland Hum Mol Genet 2006 pols set
DNA polymerases and human diseases. Joann B Sweasy, Julia M Lauper, Kristin A Eckert Radiat Res 2006 new
Promiscuous mismatch extension by human DNA polymerase lambda. Angel J Picher, Miguel García-Díaz, Katarzyna Bebenek, Lars C Pedersen, Thomas A Kunkel, Luis Blanco Nucleic acids research 2006 topics set
Effects of nucleotides and nucleotide analogue inhibitors of HIV-1 reverse transcriptase in a ratchet model of polymerase translocation. Matthias Götte Curr Pharm Des 2006 partial results
Stoichiometric complex formation by proliferating cell nuclear antigen (PCNA) and its interacting protein: purification and crystallization of the DNA polymerase and PCNA monomer mutant complex from Pyrococcus furiosus. Hirokazu Nishida, Shigeki Matsumiya, Daisuke Tsuchiya, Yoshizumi Ishino, Kosuke Morikawa Acta Crystallogr Sect F Struct Biol Cryst Commun 2006 pols set
In silico studies of the African swine fever virus DNA polymerase X support an induced-fit mechanism. Benedetta A Sampoli Benítez, Karunesh Arora, Tamar Schlick Biophys J 2006 new
Relative replication fitness of efavirenz-resistant mutants of HIV-1: correlation with frequency during clinical therapy and evidence of compensation for the reduced fitness of K103N + L100I by the nucleoside resistance mutation L74V. Christine E Koval, Carrie Dykes, Jiong Wang, Lisa M Demeter Virology 2006 pols set
Mutator phenotypes caused by substitution at a conserved motif A residue in eukaryotic DNA polymerase delta. Ranga N Venkatesan, Jessica J Hsu, Nicole A Lawrence, Bradley D Preston, Lawrence A Loeb The Journal of biological chemistry 2006 new
Chaos and order in spontaneous mutation. John W Drake Genetics 2006 topics set
A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis. Raquel Juárez, José F Ruiz, Stephanie A Nick McElhinny, Dale A Ramsden, Luis Blanco Nucleic acids research 2006 pols set
Subtle but variable conformational rearrangements in the replication cycle of Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4) may accommodate lesion bypass. Yazhen Wang, Karunesh Arora, Tamar Schlick Protein science : a publication of the Protein Society 2006 topics set
Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer. Chad A Dumstorf, Alan B Clark, Qingcong Lin, Grace E Kissling, Tao Yuan, Raju Kucherlapati, William Glenn McGregor, Thomas A Kunkel Proceedings of the National Academy of Sciences of the United States of America 2006 new
The HIV-1 reverse transcriptase mutants G190S and G190A, which confer resistance to non-nucleoside reverse transcriptase inhibitors, demonstrate reductions in RNase H activity and DNA synthesis from tRNA(Lys, 3) that correlate with reductions in replication efficiency. Jiong Wang, Carrie Dykes, R A Domaoal, Christine E Koval, R A Bambara, Lisa M Demeter Virology 2006 pols set
Simulating the effect of DNA polymerase mutations on transition-state energetics and fidelity: evaluating amino acid group contribution and allosteric coupling for ionized residues in human pol beta. Yun Xiang, Peter Oelschlaeger, Jan Florián, Myron F Goodman, Arieh Warshel Biochemistry 2006 new
Dimerization inhibitors of HIV-1 reverse transcriptase, protease and integrase: a single mode of inhibition for the three HIV enzymes? María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez, Federico Gago Antiviral research 2006 pols set
DNA polymerase gamma in mitochondrial DNA replication and repair. Maria A Graziewicz, Matthew J Longley, William C Copeland Chem Rev 2006 new
The L561A substitution in the nascent base-pair binding pocket of RB69 DNA polymerase reduces base discrimination. Haijiang Zhang, Chanu Rhee, Anna Bebenek, John W Drake, Jianhong Wang, William H Konigsberg Biochemistry 2006 complete
Dominance of HIV-1 subtype CRF01_AE in sexually acquired cases leads to a new epidemic in Yunnan province of China. Yong Zhang, Lin Lu, Lei Ba, Li Liu, Li Yang, Manhong Jia, Haibo Wang, Qing Fang, Yuhua Shi, Wenyun Yan, Guangcai Chang, Linqi Zhang, David D Ho, Zhiwei Chen PLoS medicine 2006 new
Selective anti-cytomegalovirus compounds discovered by screening for inhibitors of subunit interactions of the viral polymerase. Arianna Loregian, Donald M Coen Chemistry & biology 2006 new
DNA detection using recombination proteins. Olaf Piepenburg, Colin H Williams, Derek L Stemple, Niall A Armes PLoS Biol 2006 pols set
Delivery of telomerase reverse transcriptase small interfering RNA in complex with positively charged single-walled carbon nanotubes suppresses tumor growth. Zhuohan Zhang, Xiaoying Yang, Yongqing Zhang, Bin Zeng, Shujing Wang, Tianhui Zhu, Richard B S Roden, Yongsheng Chen, Rongcun Yang Clinical cancer research : an official journal of the American Association for Cancer Research 2006 new
DNA polymerase X from Deinococcus radiodurans possesses a structure-modulated 3'-->5' exonuclease activity involved in radioresistance. Melanie Blasius, Igor V Shevelev, Edmond Jolivet, Suzanne Sommer, Ulrich Hübscher Molecular microbiology 2006 pols set
[The value of magnifying endoscopy combined with human telomerase reverse transcriptase in diagnosing precancerous gastric lesions]. Xue-feng Lu, Zun-song Wang, Yong-chang Li, Jin-dong Fu Zhonghua nei ke za zhi [Chinese journal of internal medicine] 2006 new
Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase. Miguel Garcia-Diaz, Katarzyna Bebenek, Joseph M Krahn, Lars C Pedersen, Thomas A Kunkel Cell 2006 topics set
ATR homolog Mec1 controls association of DNA polymerase zeta-Rev1 complex with regions near a double-strand break. Yukinori Hirano, Katsunori Sugimoto Current biology : CB 2006 new
Yeast and human translesion DNA synthesis polymerases: expression, purification, and biochemical characterization. Robert E Johnson, Louise Prakash, Satya Prakash Methods in enzymology 2006 new
The DNA polymerase activity of Pol epsilon holoenzyme is required for rapid and efficient chromosomal DNA replication in Xenopus egg extracts. Koh Shikata, Taro Sasa-Masuda, Yukiko Okuno, Shou Waga, Akio Sugino BMC Biochem 2006 new
Protein trans-splicing and characterization of a split family B-type DNA polymerase from the hyperthermophilic archaeal parasite Nanoarchaeum equitans. Jeong Jin Choi, Ki Hoon Nam, Bokkee Min, Soon-Jong Kim, Dieter Söll, Suk-Tae Kwon Journal of molecular biology 2006 new
Molecular diagnosis of Alpers syndrome. Khue V Nguyen, Farida S Sharief, Sherine S L Chan, William C Copeland, Robert K Naviaux Journal of hepatology 2006 pols set
Stabilization of Taq DNA polymerase at high temperature by protein folding pathways from a hyperthermophilic archaeon, Pyrococcus furiosus. Pongpan Laksanalamai, Andrey R Pavlov, Alexei I Slesarev, Frank T Robb Biotechnol Bioeng 2006 pols set
Enhanced antitumor effect against human telomerase reverse transcriptase (hTERT) by vaccination with chemotactic-hTERT gene-modified tumor cell and the combination with anti-4-1BB monoclonal antibodies. Xiaoyan Lin, Chunxia Zhou, Shengdian Wang, Dongmei Wang, Wenbo Ma, Xiao Liang, Chen Lin, Zhengqiang Wang, Jinming Li, Sujuan Guo, Yongqing Zhang, Shuren Zhang International journal of cancer. Journal international du cancer 2006 new
Nucleotide-mimetic synthetic ligands for DNA-recognizing enzymes One-step purification of Pfu DNA polymerase. Sotirios Melissis, Nikolaos E Labrou, Yannis D Clonis J Chromatogr A 2006 pols set
Calcium is a cofactor of polymerization but inhibits pyrophosphorolysis by the Sulfolobus solfataricus DNA polymerase Dpo4. Adriana Irimia, Hong Zang, Lioudmila V Loukachevitch, Robert Lawton Eoff, F Peter Guengerich, Martin Egli Biochemistry 2006 topics set
Evaluation of a multiple-cycle, recombinant virus, growth competition assay that uses flow cytometry to measure replication efficiency of human immunodeficiency virus type 1 in cell culture. Carrie Dykes, Jiong Wang, Xia Jin, Vicente Planelles, Dong Sung An, Amanda Tallo, Yangxin Huang, Hulin Wu, Lisa M Demeter Journal of clinical microbiology 2006 pols set
Functional human mitochondrial DNA polymerase gamma forms a heterotrimer. Elena Yakubovskaya, Zhixin Chen, José A Carrodeguas, Caroline Kisker, Daniel F Bogenhagen The Journal of biological chemistry 2006 new
High-throughput screening of RNA polymerase inhibitors using a fluorescent UTP analog. Jyothi Bhat, Rajendra Rane, Suresh M Solapure, Dhiman Sarkar, Umender Sharma, M N Harish, Sarah Lamb, Darren Plant, Peter Alcock, Steve Peters, Shubhada Barde, Raman K Roy J Biomol Screen 2006 topics set
Mitochondrial and nuclear DNA defects in Saccharomyces cerevisiae with mutations in DNA polymerase gamma associated with progressive external ophthalmoplegia. Gregory R Stuart, Janine H Santos, Micheline K Strand, Bennett Van Houten, William C Copeland Hum Mol Genet 2006 pols set
HIV-1 RNase H: recent progress in an exciting, yet little explored, drug target. Enzo Tramontano Mini Rev Med Chem 2006 new
A role for replication repair in the genesis of templated mutations. Gary E Schultz, Geraldine T Carver, John W Drake Journal of molecular biology 2006 complete
Drosophila DNA polymerase zeta interacts with recombination repair protein 1, the Drosophila homologue of human abasic endonuclease 1. Ryo Takeuchi, Tatsushi Ruike, Ryo-ichi Nakamura, Kaori Shimanouchi, Yoshihiro Kanai, Yoko Abe, Ayumi Ihara, Kengo Sakaguchi The Journal of biological chemistry 2006 new
Vaccinia virus uracil DNA glycosylase interacts with the A20 protein to form a heterodimeric processivity factor for the viral DNA polymerase. Eleni S Stanitsa, Lisa Arps, Paula Traktman The Journal of biological chemistry 2006 new
Role of DNA polymerase theta in tolerance of endogenous and exogenous DNA damage in mouse B cells. Akiko Ukai, Takako Maruyama, Shigenobu Mochizuki, Rika Ouchida, Keiji Masuda, Kiyoko Kawamura, Masatoshi Tagawa, Kazuo Kinoshita, Akemi Sakamoto, Takeshi Tokuhisa, Jiyang O-Wang Genes Cells 2006 new
Association of novel POLG mutations and multiple mitochondrial DNA deletions with variable clinical phenotypes in a Spanish population. Emiliano González-Vioque, Alberto Blázquez, Daniel Fernández-Moreira, Belén Bornstein, Juan Bautista, Javier Arpa, Carmen Navarro, Yolanda Campos, Miguel A Fernández-Moreno, Rafael Garesse, Joaquin Arenas, Miguel A Martín Archives of neurology 2006 pols set
Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest. Xiaohui Bi, Laura R Barkley, Damien M Slater, Satoshi Tateishi, Masaru Yamaizumi, Haruo Ohmori, Cyrus Vaziri Molecular and cellular biology 2006 new
Human parechovirus infections in Dutch children and the association between serotype and disease severity. K S M Benschop, J Schinkel, R P Minnaar, D Pajkrt, L Spanjerberg, H C Kraakman, Ben Berkhout, H L Zaaijer, M G H M Beld, K C Wolthers Clin Infect Dis 2006 new
The polymorphic polyglutamine repeat in the mitochondrial DNA polymerase gamma gene is not associated with oligozoospermia. A Brusco, C Michielotto, V Gatta, C Foresta, G Matullo, Massimo Zeviani, Gianfrancesco Ferrari, E Dragone, G Calabrese, M Rossato, L Stuppia, N Migone Journal of endocrinological investigation 2006 new
Antiretroviral nucleosides, deoxynucleotide carrier and mitochondrial DNA: evidence supporting the DNA pol gamma hypothesis. William Lewis, James J Kohler, Seyed H Hosseini, Chad P Haase, William C Copeland, Rachelle J Bienstock, Tomika Ludaway, Jamie McNaught, Rodney Russ, Tami Stuart, Robert Santoianni AIDS (London, England) 2006 new
Escherichia coli DNA polymerase II can efficiently bypass 3,N(4)-ethenocytosine lesions in vitro and in vivo. Abu Amar M Al Mamun, M Zafri Humayun Mutation research 2006 pols set
Chlamydial DNA polymerase I can bypass lesions in vitro. Xipeng Liu, Jingli Hou, Jianhua Liu Biochem Biophys Res Commun 2006 new
Purification and characterization of Escherichia coli DNA polymerase V. Katharina Schlacher, Qingfei Jiang, Roger Woodgate, Myron F Goodman Methods in enzymology 2006 pols set
The structure of T. aquaticus DNA polymerase III is distinct from eukaryotic replicative DNA polymerases. Scott Bailey, Richard A Wing, Thomas A Steitz Cell 2006 topics set
Multiple solutions to inefficient lesion bypass by T7 DNA polymerase. Scott D McCulloch, Thomas A Kunkel DNA repair 2006 pols set
Involvement of novel human immunodeficiency virus type 1 reverse transcriptase mutations in the regulation of resistance to nucleoside inhibitors. Valentina Svicher, Tobias Sing, Maria Mercedes Santoro, Federica Forbici, Fátima Rodríguez-Barrios, Ada Bertoli, Niko Beerenwinkel, Maria Concetta Bellocchi, Federigo Gago, Antonella d'Arminio Monforte, Andrea Antinori, Thomas Lengauer, F Ceccherini-Silberstein, CF Perno Journal of virology 2006 pols set
POLG1 mutations associated with progressive encephalopathy in childhood. Gittan Kollberg, Ali-Reza Moslemi, Niklas Darin, Inger Nennesmo, Ingibjörg Bjarnadottir, Paul Uvebrant, Elisabeth Holme, Atle Melberg, Már Tulinius, Anders Oldfors Journal of neuropathology and experimental neurology 2006 pols set
Molecular analysis of polymerase gamma gene and mitochondrial polymorphism in fertile and subfertile men. T P Harris, K P Gomas, F Weir, A J Holyoake, P McHugh, Mei Wu, Y Sin, I L Sin, F Y T Sin International journal of andrology 2006 new
DNA polymerase-beta is expressed early in neurons of Alzheimer's disease brain and is loaded into DNA replication forks in neurons challenged with beta-amyloid. Agata Copani, Jeroen J M Hoozemans, Filippo Caraci, Marco Calafiore, Elise S Van Haastert, Robert Veerhuis, Annemieke J M Rozemuller, Eleonora Aronica, Maria Angela Sortino, Ferdinando Nicoletti J Neurosci 2006 new
Optimization of the Y831C mutation detection in human DNA polymerase gamma by allelic discrimination assay. Katarzyna Stopińska, Tomasz Grzybowski, Boris A Malyarchuk, Miroslava V Derenko, Danuta Miścicka-Sliwka Acta biochimica Polonica 2006 pols set
Ubiquitylation of yeast proliferating cell nuclear antigen and its implications for translesion DNA synthesis. Lajos Haracska, Ildiko Unk, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2006 new
HIV-1 reverse transcriptase structure with RNase H inhibitor dihydroxy benzoyl naphthyl hydrazone bound at a novel site. Daniel M Himmel, Stefan G Sarafianos, Sanjeewa Dharmasena, Mohammed M Hossain, Kessler McCoy-Simandle, Tatiana Ilina, Arthur D Clark, Jennifer L Knight, John G Julias, Patrick K Clark, Karsten Krogh-Jespersen, Ronald M Levy, Stephen H Hughes, Michael A. Parniak, Edward Arnold ACS Chem Biol 2006 partial results
Synthesis and anti-HIV-1 and anti-HCMV activity of 1-substituted 3-(3,5-dimethylbenzyl)uracil derivatives. Tokumi Maruyama, Shigetada Kozai, Yosuke Demizu, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoecks, Graciella Andrei, Erik De Clercq Chemical & pharmaceutical bulletin 2006 pols set
Phenotypic spectrum associated with mutations of the mitochondrial polymerase gamma gene. Rita Horvath, Gavin Hudson, Gianfrancesco Ferrari, Nancy Fütterer, Sofia Ahola, Eleonora Lamantea, Holger Prokisch, Hanns Lochmüller, Robert McFarland, V Ramesh, Thomas Klopstock, Peter Freisinger, Fabrizio Salvi, Johannes A Mayr, Rene Santer, Marketa Tesarova, Jiri Zeman, Bjarne Udd, Robert W Taylor, Douglass M Turnbull, Michael Hanna, Doreen Fialho, Anu Suomalainen, Massimo Zeviani, Patrick F Chinnery Brain : a journal of neurology 2006 pols set
POLG1, C10ORF2, and ANT1 mutations are uncommon in sporadic progressive external ophthalmoplegia with multiple mitochondrial DNA deletions. Gavin Hudson, M Deschauer, Robert W Taylor, M G Hanna, Doreen Fialho, Andrew M Schaefer, L-P He, E Blakely, Douglass M Turnbull, Patrick F Chinnery Neurology 2006 pols set
Genetic and chemical rescue of the Saccharomyces cerevisiae phenotype induced by mitochondrial DNA polymerase mutations associated with progressive external ophthalmoplegia in humans. Enrico Baruffini, Tiziana Lodi, Cristina Dallabona, Andrea Puglisi, Massimo Zeviani, Iliana Ferrero Human molecular genetics 2006 pols set
Molecular analysis of ANT1, TWINKLE and POLG in patients with multiple deletions or depletion of mitochondrial DNA by a dHPLC-based assay. Mourad Naïmi, Sylvie Bannwarth, Vincent Procaccio, Jean Pouget, Claude Desnuelle, Jean-François Pellissier, Agnes Rötig, Arnold Munnich, Patrick Calvas, Christian Richelme, Philippe Jonveaux, Giovanni Castelnovo, Mariella Simon, Melvin Simon, Michel Clanet, Douglas Wallace, Véronique Paquis-Flucklinger European journal of human genetics : EJHG 2006 pols set
The spectrum of clinical disease caused by the A467T and W748S POLG mutations: a study of 26 cases. Charalampos Tzoulis, Bernt A Engelsen, Wenche Telstad, Jan Aasly, Massimo Zeviani, Synnøve Winterthun, Gianfrancesco Ferrari, Jan H Aarseth, Laurence A Bindoff Brain : a journal of neurology 2006 pols set
The Y-family DNA polymerase kappa (pol kappa) functions in mammalian nucleotide-excision repair. Tomoo Ogi, Alan R Lehmann Nat Cell Biol 2006 new
Development of a high-throughput membrane-array method for molecular diagnosis of circulating tumor cells in patients with gastric cancers. Chan-Hang Wu, Shiu-Ru Lin, Fang-Jung Yu, Deng-Chyang Wu, Yong-Sang Pan, Jan-Sing Hsieh, Sung-Yu Huang, Jaw-Yuan Wang International journal of cancer. Journal international du cancer 2006 new
Fidelity of the human mitochondrial DNA polymerase. Harold R Lee, Kenneth A Johnson The Journal of biological chemistry 2006 new
A new photoactive building block for investigation of DNA backbone interactions: photoaffinity labeling of human DNA polymerase beta. Meike Liebmann, Francesca Di Pasquale, Andreas Marx Chembiochem 2006 pols set
POLG1 in idiopathic Parkinson disease. Watcharee Tiangyou, Gavin Hudson, D Ghezzi, Gianfrancesco Ferrari, Massimo Zeviani, David J Burn, Patrick F Chinnery Neurology 2006 pols set
An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site. Deepak T Nair, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Structure (London, England : 1993) 2006 topics set
Dynamics of loading the Escherichia coli DNA polymerase processivity clamp. Linda B Bloom Crit Rev Biochem Mol Biol 2006 pols set
Fatal neonatal-onset mitochondrial respiratory chain disease with T cell immunodeficiency. Janine Reichenbach, Ralf Schubert, Rita Horvàth, Jens Petersen, Nancy Fütterer, Elisabeth Malle, Andreas Stumpf, Boris R Gebhardt, Ulrike Koehl, Burkhart Schraven, Stefan Zielen Pediatric research 2006 pols set
Dominant inheritance of premature ovarian failure associated with mutant mitochondrial DNA polymerase gamma. Alistair T Pagnamenta, Jan-Willem Taanman, Callum J Wilson, Neil E Anderson, Rosetta Marotta, Andrew J Duncan, Maria Bitner-Glindzicz, Robert W Taylor, Adrienne Laskowski, David R Thorburn, Shamima Rahman Human reproduction (Oxford, England) 2006 pols set
Roles of DNA polymerases in replication, repair, and recombination in eukaryotes. Youri I Pavlov, Polina V Shcherbakova, Igor B Rogozin Int Rev Cytol 2006 new
Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138. Jingshan Ren, Charles E Nichols, Anna Stamp, Phillip P Chamberlain, Robert G Ferris, Kurt L Weaver, Steven A Short, David K Stammers FEBS J 2006 partial results
The structural basis for the mutagenicity of O(6)-methyl-guanine lesions. Joshua J Warren, Lawrence J Forsberg, Lorena S Beese Proceedings of the National Academy of Sciences of the United States of America 2006 topics set
Phenotypic resistance of resistant strains of HIV type-1 subtype B in China. Jinming Li, Jun-feng Lu, Hua-huang Dong, Zuo-Yi Bao, Si-Yang Liu, Han-Ping Li, Dao-Min Zhuang, Yong-Jian Liu, Hong Li, Zhengqiang Wang, Hao Wu, Jing-Yun Li Chinese medical journal 2006 new
Functional evidence for a small and rigid active site in a high fidelity DNA polymerase: probing T7 DNA polymerase with variably sized base pairs. Tae Woo Kim, Luis G Brieba, Tom Ellenberger, Eric T Kool The Journal of biological chemistry 2006 topics set
An intrinsic 5'-deoxyribose-5-phosphate lyase activity in DNA polymerase beta from Leishmania infantum supports a role in DNA repair. Ana Alonso, Gloria Terrados, Angel J Picher, Rafael Giraldo, Luis Blanco, Vicente Larraga DNA repair 2006 new
Thermal stability landscape for Klenow DNA polymerase as a function of pH and salt concentration. Allison J Richard, Chin-Chi Liu, Alexandra L Klinger, Matthew J Todd, Tara M Mezzasalma, Vince J LiCata Biochimica et biophysica acta 2006 new
Environmental stress and lesion-bypass DNA polymerases. Takehiko Nohmi Annual review of microbiology 2006 topics set
[Advances of study on human translesion synthesis DNA polymerase eta]. Gong-hua Hu, Zhi-xiong Zhuang Wei Sheng Yan Jiu 2006 new
The replication factor C clamp loader requires arginine finger sensors to drive DNA binding and proliferating cell nuclear antigen loading. Aaron Johnson, Nina Y Yao, Gregory D Bowman, John Kuriyan, Mike E O'Donnell The Journal of biological chemistry 2006 topics set
Monoubiquitination of proliferating cell nuclear antigen induced by stalled replication requires uncoupling of DNA polymerase and mini-chromosome maintenance helicase activities. Debbie J Chang, Patrick J Lupardus, Karlene A Cimprich The Journal of biological chemistry 2006 new
Incorporation and replication of 8-oxo-deoxyguanosine by the human mitochondrial DNA polymerase. Jeremiah W Hanes, David M Thal, Kenneth A Johnson The Journal of biological chemistry 2006 new
Translesion synthesis past the C8- and N2-deoxyguanosine adducts of the dietary mutagen 2-Amino-3-methylimidazo[4,5-f]quinoline in the NarI recognition sequence by prokaryotic DNA polymerases. James S Stover, Goutam Chowdhury, Hong Zang, F Peter Guengerich, Carmelo J Rizzo Chemical research in toxicology 2006 topics set
Structure-activity relationships of [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]- 3'-spiro-5' '-(4' '-amino-1' ',2' '-oxathiole-2' ',2' '-dioxide)thymine derivatives as inhibitors of HIV-1 reverse transcriptase dimerization. Nicolas Sluis-Cremer, Noureddine Hamamouch, Ana San Félix, Sonsoles Velazquez, Jan Balzarini, María-José Camarasa Journal of medicinal chemistry 2006 pols set
Translesion synthesis across polycyclic aromatic hydrocarbon diol epoxide adducts of deoxyadenosine by Sulfolobus solfataricus DNA polymerase Dpo4. Hong Zang, Goutam Chowdhury, Karen C Angel, Thomas M Harris, F Peter Guengerich Chemical research in toxicology 2006 topics set
Complex formation with Rev1 enhances the proficiency of Saccharomyces cerevisiae DNA polymerase zeta for mismatch extension and for extension opposite from DNA lesions. Narottam Acharya, Robert E Johnson, Satya Prakash, Louise Prakash Molecular and cellular biology 2006 pols set
Replication past a trans-4-hydroxynonenal minor-groove adduct by the sequential action of human DNA polymerases iota and kappa. William T Wolfle, Robert E Johnson, Irina G Minko, R Stephen Lloyd, Satya Prakash, Louise Prakash Molecular and cellular biology 2006 pols set
A new paradigm for DNA polymerase specificity. Yu-Chih Tsai, Kenneth A Johnson Biochemistry 2006 pols set
Quantitative molecular diagnosis of axillary drainage fluid for prediction of locoregional failure in patients with one to three positive axillary nodes after mastectomy without adjuvant radiotherapy. Yongqing Zhang, Qing Yong Ma, Cheng Xue Dang, M Moureau-Zabotto, Wu Ke Chen International journal of radiation oncology, biology, physics 2006 new
Nitroimidazoles, part 2: Synthesis, antiviral and antitumor activity of new 4-nitroimidazoles. Najim A Al-Masoudi, Yaseen A Al-Soud, Aris Kalogerakis, Christophe Pannecouque, Erik De Clercq Chemistry & biodiversity 2006 pols set
Role of Pseudomonas aeruginosa dinB-encoded DNA polymerase IV in mutagenesis. Laurie H Sanders, Andrea Rockel, Haiping Lu, Daniel J Wozniak, Mark D Sutton J Bacteriol 2006 pols set
A broadly applicable method to characterize large DNA viruses and adenoviruses based on the DNA polymerase gene. Larry A Hanson, Mary R Rudis, Marcia Vasquez-Lee, Roy D Montgomery Virol J 2006 new
The K65R reverse transcriptase mutation in HIV-1 reverses the excision phenotype of zidovudine resistance mutations. Kirsten L White, James M Chen, Joy Y Feng, Nicolas A Margot, John K Ly, Adrian S Ray, Holly L Macarthur, Martin J McDermott, S Swaminathan, Michael D Miller Antivir Ther 2006 topics set
Cell cycle-specific changes in hTERT promoter activity in normal and cancerous cells in adenoviral gene therapy: a promising implication of telomerase-dependent targeted cancer gene therapy. Yoshiteru Murofushi, Satoshi Nagano, Junichi Kamizono, Tomosaburo Takahashi, Hisayoshi Fujiwara, Setsuro Komiya, Toyojiro Matsuishi, Ken-ichiro Kosai International journal of oncology 2006 new
Determination of lysine pK values using [5-13C]lysine: application to the lyase domain of DNA Pol beta. Guanghua Gao, Rajendra Prasad, Siegfried N Lodwig, Clifford J Unkefer, William A Beard, Samuel H Wilson, Robert E London Journal of the American Chemical Society 2006 new
2'-Deoxy-4'-C-ethynyl-2-fluoroadenosine: a nucleoside reverse transcriptase inhibitor with highly potent activity against all HIV-1 strains, favorable toxic profiles and stability in plasma. Hiroshi Ohrui, Satoru Kohgo, Hiroyuki Hayakawa, Eiichi N Kodama, Masao Matsuoka, Tomohiro Nakata, Hiroyuki Mitsuya Nucleic Acids Symp Ser (Oxf) 2006 partial results
Lack of association between infection with a novel human coronavirus (HCoV), HCoV-NH, and Kawasaki disease in Taiwan. Luan-Yin Chang, Bor-Luen Chiang, Chuan-Liang Kao, Mei-Hwan Wu, Pei-Jer Chen, Ben Berkhout, Hui-Ching Yang, Li-Min Huang J Infect Dis 2006 new
Energy analysis of chemistry for correct insertion by DNA polymerase beta. Ping Lin, Lars C Pedersen, Vinod K Batra, William A Beard, Samuel H Wilson, Lee G Pedersen Proceedings of the National Academy of Sciences of the United States of America 2006 topics set
High prevalence of the K65R mutation in human immunodeficiency virus type 1 subtype C isolates from infected patients in Botswana treated with didanosine-based regimens. Florence Doualla-Bell, Ava Avalos, Bluma G Brenner, Tendani Gaolathe, Madisa Mine, Simani Gaseitsiwe, Maureen Oliveira, Daniella Moisi, Ndwapi Ndwapi, Howard Moffat, Max Essex, Mark A. Wainberg Antimicrobial agents and chemotherapy 2006 new
A false note of DNA polymerase iota in the choir of genome caretakers in mammals. Leonid V Gening, Alena V Makarova, A M Malashenko, Vyacheslav Z Tarantul Biochemistry (Mosc) 2006 new
Mechanistic comparison of high-fidelity and error-prone DNA polymerases and ligases involved in DNA repair. Alexander K Showalter, Brandon J Lamarche, Marina Bakhtina, Mei-I Su, Kuo-Hsiang Tang, Ming-Daw Tsai Chem Rev 2006 pols set
Removal of contaminating TEM-la beta-lactamase gene from commercial Taq DNA polymerase. Jae Seok Song, Jung Hun Lee, Jung-Hyun Lee, Byeong Chul Jeong, Won-Keun Lee, Sang Hee Lee J Microbiol 2006 pols set
Why do HIV-1 and HIV-2 use different pathways to develop AZT resistance? Paul L Boyer, Stefan G Sarafianos, Patrick K Clark, Edward Arnold, Stephen H Hughes PLoS Pathog 2006 topics set
Inhibitory effect of tocotrienol on eukaryotic DNA polymerase lambda and angiogenesis. Yoshiyuki Mizushina, Kiyotaka Nakagawa, Akira Shibata, Yasutoshi Awata, Isoko Kuriyama, Noriko Shimazaki, Osamu Koiwai, Yukinobu Uchiyama, Kengo Sakaguchi, Teruo Miyazawa, Hiromi Yoshida Biochem Biophys Res Commun 2006 pols set
RPA and PCNA suppress formation of large deletion errors by yeast DNA polymerase delta. John M Fortune, Carrie M W Stith, Grace E Kissling, Peter M J Burgers, Thomas A Kunkel Nucleic acids research 2006 new
Evidence that errors made by DNA polymerase alpha are corrected by DNA polymerase delta. Youri I Pavlov, C Frahm, Stephanie A Nick McElhinny, Atsuko Niimi, Motoshi Suzuki, Thomas A Kunkel Current biology : CB 2006 new
Homology modeling of four Y-family, lesion-bypass DNA polymerases: the case that E. coli Pol IV and human Pol kappa are orthologs, and E. coli Pol V and human Pol eta are orthologs. Chiu Hong Lee, Sushil Chandani, Edward L Loechler J Mol Graph Model 2006 topics set
Specificity of replicative and SOS-inducible DNA polymerases in frameshift mutagenesis: mutability of Salmonella typhimurium strains overexpressing SOS-inducible DNA polymerases to 30 chemical mutagens. Keiko Matsui, Masami Yamada, Masaru Imai, Kazuo Yamamoto, Takehiko Nohmi DNA repair 2006 pols set
Roles of DNA polymerase V and RecA protein in SOS damage-induced mutation. Katharina Schlacher, Phuong Pham, Michael M Cox, Myron F Goodman Chem Rev 2006 new
Involvement of Y-family DNA polymerases in mutagenesis caused by oxidized nucleotides in Escherichia coli. Masami Yamada, Tatsuo Nunoshiba, Masatomi Shimizu, Petr Gruz, Hiroyuki Kamiya, Hideyoshi Harashima, Takehiko Nohmi Journal of bacteriology 2006 pols set
A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase. Li Fan, Sangbumn Kim, Carol L Farr, Kevin T Schaefer, Kathleen M Randolph, John A Tainer, Laurie S Kaguni Journal of molecular biology 2006 complete John A Tainer*
Varying DNA base-pair size in subangstrom increments: evidence for a loose, not large, active site in low-fidelity Dpo4 polymerase. Shin Mizukami, Tae Woo Kim, Sandra A Helquist, Eric T Kool Biochemistry 2006 topics set
Inhibition of DNA polymerase eta by oxetanocin derivatives. Shunji Izuta Nucleic Acids Symp Ser (Oxf) 2006 new
[Construction of prokaryotic expression plasmid pET15b-PEP-1-CAT and expression and purification of PEP-1-CAT fusion protein]. Ling-ling Yao, Jia-ning Wang, Yong-zhang Huang, Ling-yun Guo Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2006 new
Role of hoogsteen edge hydrogen bonding at template purines in nucleotide incorporation by human DNA polymerase iota. Robert E Johnson, Lajos Haracska, Louise Prakash, Satya Prakash Molecular and cellular biology 2006 pols set
Mutations in DNA polymerase eta are not detected in squamous cell carcinoma of the skin. Eitan Glick, Lisa M White, Nathan A Elliott, Daniel Berg, Nancy B Kiviat, Lawrence A Loeb Int J Cancer 2006 new
Nucleotide insertion opposite a cyclobutane pyrimidine dimer analogue caused from photoligation by a replicative DNA polymerase. Masayuki Ogino, Daisuke Okamura, Yoshinaga Yoshimura, Kenzo Fujimoto Nucleic Acids Symp Ser (Oxf) 2006 new
Real-time monitoring of DNA polymerase activity using molecular beacon. Changbei Ma, Zhiwen Tang, Kemin Wang, Weihong Tan, Jun Li, Wei Li, Zhongjie Li, Xiaohai Yang, Huimin Li, Lingfeng Liu Anal Biochem 2006 complete Kemin Wang*
Cloning, expression, and functional characterization of the equine herpesvirus 1 DNA polymerase and its accessory subunit. Arianna Loregian, Alessandro Case, Enrico Cancellotti, Carlo Valente, Howard S Marsden, Giorgio Palù J Virol 2006 topics set
Crystal structure of the herpes simplex virus 1 DNA polymerase. Shenping Liu, John D Knafels, Jeanne S Chang, Gregory A Waszak, Eric T Baldwin, Martin R Deibel, Darrell R Thomsen, Fred L Homa, Peter A Wells, Monica C Tory, Roger A Poorman, Hua Gao, Xiayang Qiu, Andrew P Seddon The Journal of biological chemistry 2006 topics set
UV-induced RPA phosphorylation is increased in the absence of DNA polymerase eta and requires DNA-PK. Séverine Cruet-Hennequart, Seamus Coyne, Macdara T Glynn, Gregory G Oakley, Michael P Carty DNA repair 2006 complete Michael P Carty*
Structure of the Escherichia coli DNA polymerase III epsilon-HOT proofreading complex. Thomas W Kirby, Scott Harvey, Eugene F DeRose, Sergey Chalov, Anna K Chikova, Fred W Perrino, Roel M Schaaper, Robert E London, Lars C Pedersen The Journal of biological chemistry 2006 topics set
TSAO derivatives, inhibitors of HIV-1 reverse transcriptase dimerization: recent progress. María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez, María-Cruz Bonache, Sonia de Castro Current pharmaceutical design 2006 pols set
Translesion synthesis across bulky N2-alkyl guanine DNA adducts by human DNA polymerase kappa. Jeong-Yun Choi, Karen C Angel, F Peter Guengerich The Journal of biological chemistry 2006 pols set
Structure of Saccharomyces cerevisiae DNA polymerase epsilon by cryo-electron microscopy. Francisco J Asturias, Iris K Cheung, Nasim Sabouri, Olga Chilkova, Daniel Wepplo, Erik Johansson Nature structural & molecular biology 2006 pols set
The influence of the DNA polymerase gamma accessory subunit on base excision repair by the catalytic subunit. Kevin G Pinz, Daniel F Bogenhagen DNA repair 2006 pols set
DNA polymerase programmed with a hairpin DNA incorporates a multiple-instruction architecture into molecular computing. Ken Komiya, Kensaku Sakamoto, Atsushi Kameda, Masahito Yamamoto, Azuma Ohuchi, Daisuke Kiga, Shigeyuki Yokoyama, Masami Hagiya Biosystems 2006 new
A new anti conformation for N-(deoxyguanosin-8-yl)-2-acetylaminofluorene (AAF-dG) allows Watson-Crick pairing in the Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4). Liming Wang, Suse Broyde Nucleic acids research 2006 topics set
The p66 and p12 subunits of DNA polymerase delta are modified by ubiquitin and ubiquitin-like proteins. Geng Liu, Emma Warbrick Biochem Biophys Res Commun 2006 complete Emma Warbrick*
Difference in expression level and localization of DNA polymerase beta among human esophageal cancer focus, adjacent and corresponding normal tissues. Z M Dong, N G Zheng, J L Wu, S K Li, Y L Wang Dis Esophagus 2006 new
Mgs1 and Rad18/Rad5/Mms2 are required for survival of Saccharomyces cerevisiae mutants with novel temperature/cold sensitive alleles of the DNA polymerase delta subunit, Pol31. Niloofar Davoodi Vijeh Motlagh, Masayuki Seki, Dana Branzei, Takemi Enomoto DNA repair 2006 pols set
Role of helix P of the human cytomegalovirus DNA polymerase in resistance and hypersusceptibility to the antiviral drug foscarnet. Egor P Tchesnokov, Christian Gilbert, Guy Boivin, Matthias Götte J Virol 2006 pols set
Comprehensive search for DNA polymerase in the hyperthermophilic archaeon, Pyrococcus furiosus. Sonoko Ishino, Yoshizumi Ishino Nucleosides, nucleotides & nucleic acids 2006 new
A coproofreading Zn(2+)-dependent exonuclease within a bacterial replicase. Natalie M Stano, Joe Chen, Charles S McHenry Nature structural & molecular biology 2006 new
Human enhancer of rudimentary is a molecular partner of PDIP46/SKAR, a protein interacting with DNA polymerase delta and S6K1 and regulating cell growth. Amelia Smyk, Magdalena Szuminska, Katarzyna A Uniewicz, Lee M Graves, Piotr Kozlowski FEBS J 2006 new
The phi29 DNA polymerase:protein-primer structure suggests a model for the initiation to elongation transition. Satwik Kamtekar, Andrea J Berman, Jianhong Wang, José María Lázaro, Miguel de Vega, Luis Blanco, Margarita Salas, Thomas A Steitz The EMBO journal 2006 topics set
Non-nucleoside HIV-1 reverse transcriptase inhibitors, Part 7. Synthesis, antiviral activity, and 3D-QSAR investigations of novel 6-(1-naphthoyl) HEPT analogues. Lei Ji, Fen-Er Chen, Xiao-Qing Feng, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Chemical & pharmaceutical bulletin 2006 pols set
Structure and enzymatic properties of a chimeric bacteriophage RB69 DNA polymerase and single-stranded DNA binding protein with increased processivity. Siyang Sun, Linda Geng, Yousif Shamoo Proteins 2006 partial results
Mitochondrial DNA integrity is not dependent on DNA polymerase-beta activity. Alexis B Hansen, Nicholas B Griner, Jon P Anderson, Greg C Kujoth, Tomas A Prolla, Lawrence A Loeb, Eitan Glick DNA repair 2006 new
Human replication protein A can suppress the intrinsic in vitro mutator phenotype of human DNA polymerase lambda. Giovanni Maga, Igor V Shevelev, Giuseppe Villani, Silvio Spadari, Ulrich Hübscher Nucleic acids research 2006 pols set
Effects of a modified dye-labeled nucleotide spacer arm on incorporation by thermophilic DNA polymerases. Christopher Lacenere, Meil K Garg, Brian M Stoltz, Stephen R Quake Nucleosides, nucleotides & nucleic acids 2006 topics set
Over-expression and characterization of the recombinant small heat shock protein from Pyrococcus furiosus. Huayou Chen, Zhongmei Chu, Yongqing Zhang, Shengli Yang Biotechnology letters 2006 pols set
Structural relationship of curcumin derivatives binding to the BRCT domain of human DNA polymerase lambda. Toshifumi Takeuchi, Tomomi Ishidoh, Hiroshi Iijima, Isoko Kuriyama, Noriko Shimazaki, Osamu Koiwai, Kouji Kuramochi, Susumu Kobayashi, Fumio Sugawara, Kengo Sakaguchi, Hiromi Yoshida, Yoshiyuki Mizushina Genes Cells 2006 pols set
A human DNA polymerase eta complex containing Rad18, Rad6 and Rev1; proteomic analysis and targeting of the complex to the chromatin-bound fraction of cells undergoing replication fork arrest. Mayumi S Yuasa, Chikahide Masutani, Akihiko Hirano, Martin A Cohn, Masaru Yamaizumi, Yoshihiro Nakatani, Fumio Hanaoka Genes Cells 2006 pols set
Activities and mechanism of DNA polymerase beta. William A Beard, Rajendra Prasad, Samuel H Wilson Methods in enzymology 2006 new
Fission yeast Mcm10p contains primase activity. Karen Fien, Jerard Hurwitz The Journal of biological chemistry 2006 new
DNA polymerase X from African swine fever virus: quantitative analysis of the enzyme-ssDNA interactions and the functional structure of the complex. Maria J Jezewska, Agnieszka Marcinowicz, Aaron L Lucius, Wlodzimierz Bujalowski Journal of molecular biology 2006 new
Characterization of a second proliferating cell nuclear antigen (PCNA2) from Drosophila melanogaster. Tatsushi Ruike, Ryo Takeuchi, Kei-ichi Takata, Masahiko Oshige, Nobuyuki Kasai, Kaori Shimanouchi, Yoshihiro Kanai, Ryoichi Nakamura, Fumio Sugawara, Kengo Sakaguchi The FEBS journal 2006 new
Crystal structure of the catalytic alpha subunit of E. coli replicative DNA polymerase III. Meindert H Lamers, Roxana E Georgescu, Sang-Gyu Lee, Mike E O'Donnell, John Kuriyan Cell 2006 topics set
The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins. Xuejun Zhong, Parie Garg, Carrie M W Stith, Stephanie A Nick McElhinny, Grace E Kissling, Peter M J Burgers, Thomas A Kunkel Nucleic acids research 2006 new
A conserved Hsp10-like domain in Mcm10 is required to stabilize the catalytic subunit of DNA polymerase-alpha in budding yeast. Robin M Ricke, Anja-Katrin Bielinsky The Journal of biological chemistry 2006 new
Cidofovir resistance in vaccinia virus is linked to diminished virulence in mice. Graciela Andrei, Don B Gammon, Pierre Fiten, Erik De Clercq, Ghislain Opdenakker, Robert Snoeck, David H Evans Journal of virology 2006 new
Hypoxia-inducible factor-1 mediates the expression of DNA polymerase iota in human tumor cells. Akiko Ito, Nobuko Koshikawa, Shigenobu Mochizuki, Ken Omura, Keizo Takenaga Biochem Biophys Res Commun 2006 new
A new POLG1 mutation with peo and severe axonal and demyelinating sensory-motor neuropathy. L Santoro, F Manganelli, R Lanzillo, A Tessa, F Barbieri, F Pierelli, G Di Giacinto, V Nigro, F M Santorelli Journal of neurology 2006 pols set
Modification of human immunodeficiency virus type 1 reverse transcriptase to target cells with elevated cellular dNTP concentrations. Varuni K Jamburuthugoda, Pauline Chugh, Baek Kim The Journal of biological chemistry 2006 new
Replacement of the metabolically labile methyl esters in the alkenyldiarylmethane series of non-nucleoside reverse transcriptase inhibitors with isoxazolone, isoxazole, oxazolone, or cyano substituents. Bo-Liang Deng, Tracy L Hartman, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman Journal of medicinal chemistry 2006 new
SANDO: two novel mutations in POLG1 gene. Miguel Fernandes Gago, M J Rosas, Joana Guimarães, Mariana Ferreira, Laura Vilarinho, Lígia Castro, Stirling Carpenter Neuromuscular disorders : NMD 2006 pols set
DNA polymerase eta, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates the DNA damage checkpoint and p53 activation. Gang Liu, Xinbin Chen Molecular and cellular biology 2006 new
Characterization of the global transcriptional responses to different types of DNA damage and disruption of replication in Bacillus subtilis. Alexi I Goranov, Elke Kuester-Schoeck, Jue D Wang, Alan D Grossman Journal of bacteriology 2006 new
Dynamics of nucleotide incorporation: snapshots revealed by 2-aminopurine fluorescence studies. Chithra Hariharan, Linda B Bloom, Sandra A Helquist, Eric T Kool, Linda J Reha-Krantz Biochemistry 2006 partial results
DNA polymerase catalysis in the absence of Watson-Crick hydrogen bonds: analysis by single-turnover kinetics. Olga Potapova, Chikio Chan, Angela M DeLucia, Sandra A Helquist, Eric T Kool, Nigel D F Grindley, Catherine M Joyce Biochemistry 2006 new
Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase. Steven A Jacobs, Elaine R Podell, Thomas R Cech Nature structural & molecular biology 2006 partial results
p53 deficiency rescues apoptosis and differentiation of multiple cell types in zebrafish flathead mutants deficient for zygotic DNA polymerase delta1. N Plaster, C Sonntag, C E Busse, M Hammerschmidt Cell Death Differ 2006 new
Antiviral properties of new arylsulfone derivatives with activity against human betaherpesviruses. Lieve Naesens, Chad E Stephens, Graciela Andrei, Arianna Loregian, Leen De Bolle, Robert Snoeck, J Walter Sowell, Erik De Clercq Antiviral research 2006 new
GINS is a DNA polymerase epsilon accessory factor during chromosomal DNA replication in budding yeast. Takashi Seki, Masaki Akita, Yoichiro Kamimura, Sachiko Muramatsu, Hiroyuki Araki, Akio Sugino The Journal of biological chemistry 2006 new
Efficient and high fidelity incorporation of dCTP opposite 7,8-dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA polymerase Dpo4. Hong Zang, Adriana Irimia, Jeong-Yun Choi, Karen C Angel, Lioudmila V Loukachevitch, Martin Egli, F Peter Guengerich The Journal of biological chemistry 2006 topics set
The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replication. Kumiko Matsuno, Maya Kumano, Yumiko Kubota, Yoshitami Hashimoto, Haruhiko Takisawa Molecular and cellular biology 2006 new
Synthesis and anti-HIV activity of new alkenyldiarylmethane (ADAM) non-nucleoside reverse transcriptase inhibitors (NNRTIs) incorporating benzoxazolone and benzisoxazole rings. Bo-Liang Deng, Matthew D Cullen, Zhigang Zhou, Tracy L Hartman, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Phillip E Fanwick, Mark Cushman Bioorganic & medicinal chemistry 2006 pols set
[A new method of molecular marker--RMAPD]. Xian-Yong Lan, Hong Chen, Yong-De Zhang, Wei-Bin Sun, Chu-Zhao Lei Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji 2006 new
Structure of the theta subunit of Escherichia coli DNA polymerase III in complex with the epsilon subunit. Max A Keniry, Ah Young Park, Elisabeth A Owen, Samir M Hamdan, Guido Pintacuda, Gottfried Otting, Nicholas E Dixon J Bacteriol 2006 topics set
Immortalization of normal human cytotrophoblast cells by reconstitution of telomeric reverse transcriptase activity. Yan-ling Wang, Wei Qiu, Hui-chen Feng, Yu-xia Li, Lin-zhi Zhuang, Zhengqiang Wang, Yu Liu, Jin-qiu Zhou, Deng-hong Zhang, George S W Tsao Molecular human reproduction 2006 new
Single-strand-specific exonucleases prevent frameshift mutagenesis by suppressing SOS induction and the action of DinB/DNA polymerase IV in growing cells. Megan N Hersh, Liza D Morales, Kimberly J Ross, Susan M Rosenberg J Bacteriol 2006 new
The role of DNA polymerase iota in UV mutational spectra. Jun-Hyuk Choi, Ahmad Besaratinia, Dong-Hyun Lee, Chong-Soon Lee, Gerd P Pfeifer Mutation research 2006 new
Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion. Olga Rechkoblit, Lucy Malinina, Yuan Cheng, Vitaly Kuryavyi, Suse Broyde, Nicholas E Geacintov, Dinshaw J Patel PLoS Biol 2006 topics set
Short-term antiviral activity of TMC278--a novel NNRTI--in treatment-naive HIV-1-infected subjects. Frank Goebel, Alexy Yakovlev, Anton L Pozniak, Elena Vinogradova, Griet Boogaerts, Richard Hoetelmans, Marie-Pierre P De Béthune, Monika Peeters, Brian Woodfall AIDS 2006 new
Large fragment Bst DNA polymerase for whole genome amplification of DNA from formalin-fixed paraffin-embedded tissues. Sarit Aviel-Ronen, Chang Qi Zhu, Bradley P Coe, Ni Liu, Spencer K Watson, Wan L Lam, Ming Sound Tsao BMC Genomics 2006 pols set
The plasmid RK2 replication initiator protein (TrfA) binds to the sliding clamp beta subunit of DNA polymerase III: implication for the toxicity of a peptide derived from the amino-terminal portion of 33-kilodalton TrfA. Kritaya Kongsuwan, Peter Josh, Marc J Picault, Gene Wijffels, Brian P Dalrymple J Bacteriol 2006 new
Analysis of equid herpesvirus 1 strain variation reveals a point mutation of the DNA polymerase strongly associated with neuropathogenic versus nonneuropathogenic disease outbreaks. J Nugent, I Birch-Machin, K C Smith, J A Mumford, Z Swann, J R Newton, R J Bowden, G P Allen, N Davis-Poynter J Virol 2006 new
Early-onset familial parkinsonism due to POLG mutations. Guido Davidzon, Paul Greene, Michelangelo Mancuso, Kevin J Klos, J Eric Ahlskog, Michio Hirano, Salvatore DiMauro Annals of neurology 2006 pols set
Human DNA polymerase kappa forms nonproductive complexes with matched primer termini but not with mismatched primer termini. Karissa D Carlson, Robert E Johnson, Louise Prakash, Satya Prakash, M Todd Washington Proceedings of the National Academy of Sciences of the United States of America 2006 complete M Todd Washington*
[Security of dual cancer-specific targeting vector and its cytotoxic effect when harbored]. Juan Wang, Jin-Fa Gu, Shui-Yun Yang, Tian Xiao, Rong Qi, Lan-Ying Sun, Xin-Yuan Liu Ai zheng = Aizheng = Chinese journal of cancer 2006 new
Synthetic analogues of the manzamenones and plakoridines which inhibit DNA polymerase. Jeremy R Doncaster, Laura L Etchells, Neil M Kershaw, Ryoichi Nakamura, Hazel Ryan, Ryo Takeuchi, Kengo Sakaguchi, Ali Sardarian, Roger C Whitehead Bioorganic & medicinal chemistry letters 2006 new
Regulation of replication protein A functions in DNA mismatch repair by phosphorylation. Shuangli Guo, Yongqing Zhang, Fenghua Yuan, Yin Gao, Liya Gu, Isaac Wong, Guo-Min Li The Journal of biological chemistry 2006 new
Crystal structure of intein homing endonuclease II encoded in DNA polymerase gene from hyperthermophilic archaeon Thermococcus kodakaraensis strain KOD1. Hiroyoshi Matsumura, Hitomi Takahashi, Tsuyoshi Inoue, Takahiko Yamamoto, Hiroshi Hashimoto, Motomu Nishioka, Shinsuke Fujiwara, Masahiro Takagi, Tadayuki Imanaka, Yasushi Kai Proteins 2006 new
A novel function of DNA polymerase zeta regulated by PCNA. Matthew R Northam, Parie Garg, Dmitri M Baitin, Peter M J Burgers, Polina V Shcherbakova The EMBO journal 2006 new
Novel non-nucleobase inhibitors of Staphylococcus aureus DNA polymerase IIIC. Yannick Rose, Stéphane Ciblat, Ranga Reddy, Adam C Belley, Evelyne Dietrich, Dario Lehoux, Geoffrey A McKay, Hugo Poirier, Adel Rafai Far, Daniel Delorme Bioorganic & medicinal chemistry letters 2006 new
Inhibition of human telomerase reverse transcriptase by nonsteroidal antiinflammatory drugs in colon carcinoma. Hua He, Harry Hua-Xiang Xia, Ji De Wang, Qing Gu, Marie Chia-Mi Lin, Bing Zou, Shiu Kum Lam, Annie O O Chan, Man Fung Yuen, Hsiang Fu Kung, Benjamin Chun-Yu Wong Cancer 2006 new
The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase beta. Jeanine A Harrigan, David M Wilson, Rajendra Prasad, Patricia L Opresko, Gad Beck, Alfred May, Samuel H Wilson, Vilhelm A Bohr Nucleic acids research 2006 new
Human DNA polymerase N (POLN) is a low fidelity enzyme capable of error-free bypass of 5S-thymine glycol. Kei-ichi Takata, Tatsuhiko Shimizu, Shigenori Iwai, Richard D Wood The Journal of biological chemistry 2006 partial results
Structure and mechanism of DNA polymerase Beta. William A Beard, Samuel H Wilson Chem Rev 2006 topics set
Kinetic evidence for inefficient and error-prone bypass across bulky N2-guanine DNA adducts by human DNA polymerase iota. Jeong-Yun Choi, F Peter Guengerich The Journal of biological chemistry 2006 pols set
The DNA polymerase lambda is required for the repair of non-compatible DNA double strand breaks by NHEJ in mammalian cells. Jean-Pascal Capp, François Boudsocq, Pascale Bertrand, Audrey Laroche-Clary, Philippe Pourquier, Bernard S Lopez, Christophe Cazaux, Jean-Sébastien Hoffmann, Yvan Canitrot Nucleic acids research 2006 new
Arylthiopyrrole (AThP) derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors: synthesis, structure-activity relationships, and docking studies (part 2). Antonio Lavecchia, Roberta Costi, Marino Artico, Gaetano Miele, Ettore Novellino, Alberto Bergamini, Emmanuele Crespan, Giovanni Maga, Roberto Di Santo ChemMedChem 2006 pols set
DNA polymerase 4 of Saccharomyces cerevisiae is important for accurate repair of methyl-methanesulfonate-induced DNA damage. Catherine H Sterling, Joann B Sweasy Genetics 2006 new
Arylthiopyrrole (AThP) derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors: synthesis, structure-activity relationships, and docking studies (part 1). Roberto Di Santo, Roberta Costi, Marino Artico, Gaetano Miele, Antonio Lavecchia, Ettore Novellino, Alberto Bergamini, Reynel Cancio, Giovanni Maga ChemMedChem 2006 pols set
DNA polymerase epsilon associates with the elongating form of RNA polymerase II and nascent transcripts. Anna K Rytkönen, Tomi Hillukkala, Markku Vaara, Miiko Sokka, Maarit Jokela, Raija Sormunen, Heinz Peter Nasheuer, Tamar Nethanel, Gabriel Kaufmann, Helmut Pospiech, Juhani E Syväoja FEBS J 2006 partial results
Design, synthesis, biological evaluation, and molecular modeling studies of TIBO-like cyclic sulfones as non-nucleoside HIV-1 reverse transcriptase inhibitors. Roberto Di Santo, Roberta Costi, Marino Artico, Rino Ragno, Antonio Lavecchia, Ettore Novellino, Enrico Gavuzzo, Francesco La Torre, Roberto Cirilli, Reynel Cancio, Giovanni Maga ChemMedChem 2006 pols set
A high-throughput, high-resolution strategy for the study of site-selective DNA binding agents: analysis of a "highly twisted" benzimidazole-diamidine. Kristie D Goodwin, Mark A Lewis, Farial A Tanious, Richard R Tidwell, W David Wilson, Millie M Georgiadis, Eric C Long Journal of the American Chemical Society 2006 topics set
Origins of human mitochondrial point mutations as DNA polymerase gamma-mediated errors. Weiming Zheng, Konstantin Khrapko, Hilary A Coller, William G Thilly, William C Copeland Mutation research 2006 new
Combining mutations in HIV-1 reverse transcriptase with mutations in the HIV-1 polypurine tract affects RNase H cleavages involved in PPT utilization. Mary Jane McWilliams, John G Julias, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes Virology 2006 pols set
An unnatural hydrophobic base pair system: site-specific incorporation of nucleotide analogs into DNA and RNA. Ichiro Hirao, Michiko Kimoto, Tsuneo Mitsui, Tsuyoshi Fujiwara, Rie Kawai, Akira Sato, Yoko Harada, Shigeyuki Yokoyama Nature methods 2006 topics set
Raloxifene increases proliferation and up-regulates telomerase activity in human umbilical vein endothelial cells. Masakazu Doshida, Masahide Ohmichi, Seiji Tsutsumi, Jun Kawagoe, Tomosaburo Takahashi, Botao Du, Akiko Mori-Abe, Tsuyoshi Ohta, Maki Saitoh-Sekiguchi, Kazuhiro Takahashi, Hirohisa Kurachi The Journal of biological chemistry 2006 new
Functional characterization of highly processive protein-primed DNA polymerases from phages Nf and GA-1, endowed with a potent strand displacement capacity. Elisa Longás, Miguel de Vega, José María Lázaro, Margarita Salas Nucleic acids research 2006 partial results
Arginine methylation regulates DNA polymerase beta. Nazim El-Andaloussi, Taras Valovka, Magali Toueille, Roland Steinacher, Frauke Focke, Peter Gehrig, Marcela Covic, Paul O Hassa, Primo Schär, Ulrich Hübscher, Michael O Hottiger Molecular cell 2006 new
Translesion synthesis across O6-alkylguanine DNA adducts by recombinant human DNA polymerases. Jeong-Yun Choi, Goutam Chowdhury, Hong Zang, Karen C Angel, Choua C Vu, Lisa A Peterson, F Peter Guengerich The Journal of biological chemistry 2006 pols set
Indolyl aryl sulphones as HIV-1 non-nucleoside reverse transcriptase inhibitors: synthesis, biological evaluation and binding mode studies of new derivatives at indole-2-carboxamide. Gabriella De Martino, Giuseppe La Regina, Rino Ragno, Antonio Coluccia, Alberto Bergamini, Chiara Ciaprini, Anna Sinistro, Giovanni Maga, Emmanuele Crespan, Marino Artico, Romano Silvestri Antiviral chemistry & chemotherapy 2006 pols set
Telomere repeat binding factor 2 interacts with base excision repair proteins and stimulates DNA synthesis by DNA polymerase beta. Meltem Muftuoglu, Heng Kuan Wong, Syed Z Imam, David M Wilson, Vilhelm A Bohr, Patricia L Opresko Cancer research 2006 new
Crystal structure of a DNA polymerase sliding clamp from a Gram-positive bacterium. Maria A Argiriadi, Eric R Goedken, Irina Bruck, Mike E O'Donnell, John Kuriyan BMC Struct Biol 2006 new
[Vector-mediated RNA interference of DNA polymerase beta in human bronchial epithelial cells]. Da-Lin Hu, Zhi-Xiong Zhuang, Yi-min Liu, Yun He Wei Sheng Yan Jiu 2006 new
UV-B radiation induces epithelial tumors in mice lacking DNA polymerase eta and mesenchymal tumors in mice deficient for DNA polymerase iota. Tsuyoshi Ohkumo, Yuji Kondo, Masayuki Yokoi, Tetsuya Tsukamoto, Ayumi Yamada, Taiki Sugimoto, Rie Kanao, Yujiro Higashi, Hisato Kondoh, Masae Tatematsu, Chikahide Masutani, Fumio Hanaoka Molecular and cellular biology 2006 new
Beta-sitosterol-3-O-beta-D-glucopyranoside: a eukaryotic DNA polymerase lambda inhibitor. Yoshiyuki Mizushina, Rumi Nakanishi, Isoko Kuriyama, Kohei Kamiya, Toshiko Satake, Noriko Shimazaki, Osamu Koiwai, Yukinobu Uchiyama, Yuko Yonezawa, Masaharu Takemura, Kengo Sakaguchi, Hiromi Yoshida J Steroid Biochem Mol Biol 2006 pols set
Catechin conjugated with fatty acid inhibits DNA polymerase and angiogenesis. Kiminori Matsubara, Akiko Saito, Akira Tanaka, Noriyuki Nakajima, Reiko Akagi, Masaharu Mori, Yoshiyuki Mizushina DNA Cell Biol 2006 new
The checkpoint clamp activates Mec1 kinase during initiation of the DNA damage checkpoint. Jerzy Majka, Anita Niedziela-Majka, PeterMJ Burgers Molecular cell 2006 new
Deoxyribophosphate lyase activity of mammalian endonuclease VIII-like proteins. Inga R Grin, Svetlana N Khodyreva, Georgy A Nevinsky, Dmitry O Zharkov FEBS letters 2006 new
Regulation of DNA repair fidelity by molecular checkpoints: "gates" in DNA polymerase beta's substrate selection. Ravi Radhakrishnan, Karunesh Arora, Yazhen Wang, William A Beard, Samuel H Wilson, Tamar Schlick Biochemistry 2006 new
Haploinsufficiency in DNA polymerase beta increases cancer risk with age and alters mortality rate. Diane C Cabelof, Yuji Ikeno, Abraham Nyska, Rita A Busuttil, Njwen Anyangwe, Jan Vijg, Larry H Matherly, James D Tucker, Samuel H Wilson, Arlan Richardson, Ahmad R Heydari Cancer research 2006 new
Human terminal deoxynucleotidyl transferases as novel targets for anticancer chemotherapy. Roberto Di Santo, Giovanni Maga Current medicinal chemistry 2006 new
Comparative analysis of eubacterial DNA polymerase III alpha subunits. Xiao-Qian Zhao, Jian-Fei Hu, Jun Yu Genomics Proteomics Bioinformatics 2006 new
Inhibitory effect of monogalactosyldiacylglycerol, extracted from spinach using supercritical CO2, on mammalian DNA polymerase activity. Hiroshi Iijima, Keiichi Musumi, Takahiko Hada, Naoki Maeda, Yuko Yonezawa, Hiromi Yoshida, Yoshiyuki Mizushina J Agric Food Chem 2006 pols set
Arabidopsis TEBICHI, with helicase and DNA polymerase domains, is required for regulated cell division and differentiation in meristems. Soichi Inagaki, Takamasa Suzuki, Masa-aki Ohto, Hiroko Urawa, Takashi Horiuchi, Kenzo Nakamura, Atsushi Morikami Plant Cell 2006 pols set
Indolopyridones inhibit human immunodeficiency virus reverse transcriptase with a novel mechanism of action. Dirk Jochmans, Jérôme Deval, Bart Kesteleyn, Herwig Van Marck, Eva Bettens, Inky De Baere, Pascale Dehertogh, Tania Ivens, Marcia Van Ginderen, Bertrand Van Schoubroeck, Maryam Ehteshami, Piet Wigerinck, Matthias Götte, Kurt Hertogs J Virol 2006 partial results
Increased susceptibility to UV-induced skin carcinogenesis in polymerase eta-deficient mice. Qingcong Lin, Alan B Clark, Scott D McCulloch, Tao Yuan, Roderick T Bronson, Thomas A Kunkel, Raju Kucherlapati Cancer research 2006 new
Specific amino acid residues in the beta sliding clamp establish a DNA polymerase usage hierarchy in Escherichia coli. Mark D Sutton, Jill M Duzen DNA repair 2006 new
Role of the second-largest subunit of DNA polymerase alpha in the interaction between the catalytic subunit and hyperphosphorylated retinoblastoma protein in late S phase. Masaharu Takemura, Shonen Yoshida, Tetsu Akiyama, Masatoshi Kitagawa, Yoshiji Yamada Biochimica et biophysica acta 2006 new
Effect of ultrasound on DNA polymerase reactions: monitoring on a 27-MHz quartz crystal microbalance. Yu Hoshino, Takayoshi Kawasaki, Yoshio Okahata Biomacromolecules 2006 new
A dynamic model for replication protein A (RPA) function in DNA processing pathways. Ellen Fanning, Vitaly Klimovich, Andrew R Nager Nucleic acids research 2006 topics set
HIV-1 subtype C viruses rapidly develop K65R resistance to tenofovir in cell culture. Bluma G Brenner, Maureen Oliveira, Florence Doualla-Bell, Daniela D Moisi, Michel L Ntemgwa, Fernando A Frankel, Max Essex, Mark A. Wainberg AIDS (London, England) 2006 new
Efficiency of exonucleolytic action of apurinic/apyrimidinic endonuclease 1 towards matched and mismatched dNMP at the 3' terminus of different oligomeric DNA structures correlates with thermal stability of DNA duplexes. Nadezhda S Dyrkheeva, Alexander A Lomzov, Dmitriy V Pyshnyi, Svetlana N Khodyreva, Olga I Lavrik Biochimica et biophysica acta 2006 new
3'-5' exonuclease activity of human apurinic/apyrimidinic endonuclease 1 towards DNAs containing dNMP and their modified analogs at the 3 end of single strand DNA break. Nadezhda S Dyrkheeva, Svetlana N Khodyreva, Maria V Sukhanova, I V Safronov, Sergey V Dezhurov, Olga I Lavrik Biochemistry. Biokhimii͡a 2006 new
Lagging strand replication proteins in genome stability and DNA repair. Marie L Rossi, Vandana Purohit, Patrick D Brandt, Robert A Bambara Chem Rev 2006 topics set
5-(Hydroxymethyl)-2-furfural: a selective inhibitor of DNA polymerase lambda and terminal deoxynucleotidyltransferase. Yoshiyuki Mizushina, Etsuko Yagita, Kouji Kuramochi, Isoko Kuriyama, Noriko Shimazaki, Osamu Koiwai, Yukinobu Uchiyama, Yuko Yomezawa, Fumio Sugawara, Susumu Kobayashi, Kengo Sakaguchi, Hiromi Yoshida Arch Biochem Biophys 2006 pols set
Structure of DNA polymerase beta with a benzo[c]phenanthrene diol epoxide-adducted template exhibits mutagenic features. Vinod K Batra, David D Shock, Rajendra Prasad, William A Beard, Esther W Hou, Lars C Pedersen, Jane M Sayer, Haruhiko Yagi, Subodh Kumar, Donald M Jerina, Samuel H Wilson Proceedings of the National Academy of Sciences of the United States of America 2006 topics set
Magnesium-induced assembly of a complete DNA polymerase catalytic complex. Vinod K Batra, William A Beard, David D Shock, Joseph M Krahn, Lars C Pedersen, Samuel H Wilson Structure (London, England : 1993) 2006 complete Samuel H Wilson*
NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells. Aditi Das, Lee Wiederhold, John B Leppard, Padmini S Kedar, Rajendra Prasad, Huxian Wang, Istvan Boldogh, Feridoun Karimi-Busheri, Michael Weinfeld, Alan E Tomkinson, Samuel H Wilson, Sankar Mitra, Tapas K Hazra DNA repair 2006 new
Is base excision repair a tumor suppressor mechanism? Joann B Sweasy, Tieming Lang, Daniel Dimaio Cell cycle (Georgetown, Tex.) 2006 new
Mitochondrial genome of the moon jelly Aurelia aurita (Cnidaria, Scyphozoa): A linear DNA molecule encoding a putative DNA-dependent DNA polymerase. Zhiyong Shao, Shannon Graf, Oleg Y Chaga, Dennis V Lavrov Gene 2006 new
Recent progress in the design of small molecule inhibitors of HIV RNase H. Klaus Klumpp, Tara Mirzadegan Curr Pharm Des 2006 new
Loss of DNA polymerase zeta causes chromosomal instability in mammalian cells. John P Wittschieben, Shalini C Reshmi, Susanne M Gollin, Richard D Wood Cancer research 2006 new
Thermostable DNA polymerases can perform translesion synthesis using 8-oxoguanine and tetrahydrofuran-containing DNA templates. Ekaterina A Belousova, Nadejda I Rechkunova, Olga I Lavrik Biochimica et biophysica acta 2006 new
A novel role of DNA polymerase eta in modulating cellular sensitivity to chemotherapeutic agents. Yih-Wen Chen, James E Cleaver, Fumio Hanaoka, Ching-fang Chang, Kai-Ming Chou Molecular cancer research : MCR 2006 new
Up-regulation of the fidelity of human DNA polymerase lambda by its non-enzymatic proline-rich domain. Kevin A Fiala, Wade W Duym, Jun Zhang, Zucai Suo The Journal of biological chemistry 2006 pols set
Conserved XPB core structure and motifs for DNA unwinding: implications for pathway selection of transcription or excision repair. Li Fan, Andrew S Arvai, Priscilla K Cooper, Shigenori Iwai, Fumio Hanaoka, John A Tainer Molecular cell 2006 new
Normal hypermutation in antibody genes from congenic mice defective for DNA polymerase iota. Stella A Martomo, William W Yang, Alexandra Vaisman, Alex Maas, Masayuki Yokoi, Jan H Hoeijmakers, Fumio Hanaoka, Roger Woodgate, Patricia J Gearhart DNA repair 2006 new
Kinetics of error generation in homologous B-family DNA polymerases. Matthew Hogg, Wendy Cooper, Linda J Reha-Krantz, Susan S Wallace Nucleic acids research 2006 partial results
Inhibitory effect of sulfoquinovosyl diacylglycerol on prokaryotic DNA polymerase I activity and cell growth of Escherichia coli. Tomoyuki Furukawa, Masayuki Nishida, Takahiko Hada, Kouji Kuramochi, Fumio Sugawara, Susumu Kobayashi, Hiroshi Iijima, Hiroaki Shimada, Hiromi Yoshida, Yoshiyuki Mizushina J Oleo Sci 2006 pols set
Inhibitory effects of glycolipids fraction from spinach on mammalian DNA polymerase activity and human cancer cell proliferation. Isoko Kuriyama, Keiichi Musumi, Yuko Yonezawa, Masaharu Takemura, Naoki Maeda, Hiroshi Iijima, Takahiko Hada, Hiromi Yoshida, Yoshiyuki Mizushina J Nutr Biochem 2005 pols set
Contribution of DNA polymerase eta to immunoglobulin gene hypermutation in the mouse. Frédéric Delbos, Annie De Smet, Ahmad Faili, Said Aoufouchi, Jean-Claude Weill, Claude-Agnès Reynaud J Exp Med 2005 new
Accuracy, precision, and consistency of expert HIV type 1 genotype interpretation: an international comparison (The GUESS Study). Andrew R Zolopa, Laura C Lazzeroni, Alex Rinehart, Françoise Brun Vezinet, François Clavel, Ann Collier, Brian Conway, Roy M Gulick, Mark Holodniy, CF Perno, Robert W Shafer, Douglas D Richman, Mark A. Wainberg, Daniel R Kuritzkes Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2005 pols set
Modulation of cellular response to cisplatin by a novel inhibitor of DNA polymerase beta. François Boudsocq, P Benaim, Yvan Canitrot, Martine Knibiehler, Frédéric Ausseil, Jean-Pascal Capp, Anne Bieth, Christophe Long, Bruno David, Igor V Shevelev, E Frierich-Heinecken, Ulrich Hübscher, F Amalric, Georges Massiot, Jean-Sébastien Hoffmann, Christophe Cazaux Mol Pharmacol 2005 new
A combination of decreased NRTI incorporation and decreased excision determines the resistance profile of HIV-1 K65R RT. Kirsten L White, Nicolas A Margot, John K Ly, James M Chen, Adrian S Ray, Martina Pavelko, Ruth Wang, Martin J McDermott, S Swaminathan, Michael D Miller Aids 2005 topics set
The common A467T mutation in the human mitochondrial DNA polymerase (POLG) compromises catalytic efficiency and interaction with the accessory subunit. Sherine S L Chan, Matthew J Longley, William C Copeland The Journal of biological chemistry 2005 pols set
Drug resistance mutations in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase differentially affect the phosphorolysis-dependent primer unblocking activity in the presence of stavudine and zidovudine and its inhibition by efavirenz. Emmanuele Crespan, Giada A Locatelli, Reynel Cancio, Ulrich Hübscher, Silvio Spadari, Giovanni Maga Antimicrobial agents and chemotherapy 2005 pols set
Using 2-aminopurine fluorescence to detect bacteriophage T4 DNA polymerase-DNA complexes that are important for primer extension and proofreading reactions. Chithra Hariharan, Linda J Reha-Krantz Biochemistry 2005 complete
Analysis of cytomegalovirus DNA polymerase (UL54) mutations in solid organ transplant patients receiving valganciclovir or ganciclovir prophylaxis. Guy Boivin, Nathalie Goyette, Christian Gilbert, Emma Covington J Med Virol 2005 new
Evidence for a Watson-Crick hydrogen bonding requirement in DNA synthesis by human DNA polymerase kappa. William T Wolfle, M Todd Washington, Eric T Kool, Thomas E Spratt, Sandra A Helquist, Louise Prakash, Satya Prakash Molecular and cellular biology 2005 topics set
5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family. Antonello Mai, Marino Artico, Rino Ragno, Gianluca Sbardella, Silvio Massa, Chiara Musiu, Massimo Mura, Flavia Marturana, Alessandra Cadeddu, Giovanni Maga, Paolo La Colla Bioorganic & medicinal chemistry 2005 pols set
[Screening and cloning of the genes of protein interacting with the N-terminal protein of hepatitis B virus DNA polymerase by yeast-two hybrid technique]. Guo-feng Chen, Liming Wang, Jun Cheng, Ling-xia Zhang, Lin Li, Jian Zhang, Qing Shao, Dong Ji Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2005 new
A unique loop in T7 DNA polymerase mediates the binding of helicase-primase, DNA binding protein, and processivity factor. Samir M Hamdan, Boriana Marintcheva, Timothy E Cook, Seung-Joo Lee, Stanley Tabor, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 2005 pols set
Clusters of mutations from transient hypermutability. John W Drake, Anna Bebenek, Grace E Kissling, Shyamal Peddada Proceedings of the National Academy of Sciences of the United States of America 2005 complete
POLG mutations and Alpers syndrome. Guido Davidzon, Michelangelo Mancuso, Silvio Ferraris, Catarina Quinzii, Michio Hirano, Heidi L Peters, Denise Kirby, David R Thorburn, Salvatore DiMauro Annals of neurology 2005 pols set
Roles of the Escherichia coli RecA protein and the global SOS response in effecting DNA polymerase selection in vivo. Robert W Maul, Mark D Sutton J Bacteriol 2005 new
Interaction between the T4 helicase loading protein (gp59) and the DNA polymerase (gp43): unlocking of the gp59-gp43-DNA complex to initiate assembly of a fully functional replisome. Jun Xi, Zhiquan Zhang, Zhihao Zhuang, Jingsong Yang, Michelle M Spiering, Gordon G Hammes, Stephen J Benkovic Biochemistry 2005 topics set
Dual roles for DNA polymerase eta in homologous DNA recombination and translesion DNA synthesis. Takuo Kawamoto, Kasumi Araki, Eiichiro Sonoda, Yukiko M Yamashita, Kouji Harada, Koji Kikuchi, Chikahide Masutani, Fumio Hanaoka, Kazuhiko Nozaki, Nobuo Hashimoto, Shunichi Takeda Molecular cell 2005 complete Shunichi Takeda*
Dissecting the effects of DNA polymerase and ribonuclease H inhibitor combinations on HIV-1 reverse-transcriptase activities. Cathryn A Shaw-Reid, Bradley Feuston, Vandna Munshi, Krista Getty, Julie Krueger, Daria J Hazuda, Michael A. Parniak, Michael D Miller, Dale Lewis Biochemistry 2005 pols set
Novel 1-[2-(diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. A structure-activity relationship investigation. Gabriella De Martino, Giuseppe La Regina, Alessandra Di Pasquali, Rino Ragno, Alberto Bergamini, Chiara Ciaprini, Anna Sinistro, Giovanni Maga, Emmanuele Crespan, Marino Artico, Romano Silvestri Journal of medicinal chemistry 2005 pols set
Human DNA polymerase iota incorporates dCTP opposite template G via a G.C + Hoogsteen base pair. Deepak T Nair, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Structure (London, England : 1993) 2005 topics set
High sequence conservation of human immunodeficiency virus type 1 reverse transcriptase under drug pressure despite the continuous appearance of mutations. F Ceccherini-Silberstein, Federico Gago, Maria Mercedes Santoro, Caterina Gori, Valentina Svicher, Fátima Rodríguez-Barrios, Roberta d'Arrigo, Massimo Ciccozzi, Ada Bertoli, Antonella d'Arminio Monforte, Jan Balzarini, Andrea Antinori, CF Perno Journal of virology 2005 pols set
Fidelity of mispair formation and mispair extension is dependent on the interaction between the minor groove of the primer terminus and Arg668 of DNA polymerase I of Escherichia coli. Melodie D McCain, Aviva S Meyer, Sherri S Schultz, Athanasios Glekas, Thomas E Spratt Biochemistry 2005 pols set
Tumor suppressor APC blocks DNA polymerase beta-dependent strand displacement synthesis during long patch but not short patch base excision repair and increases sensitivity to methylmethane sulfonate. Satya Narayan, Aruna S Jaiswal, Ramesh Balusu The Journal of biological chemistry 2005 new
Phosphorylation of human DNA polymerase lambda by the cyclin-dependent kinase Cdk2/cyclin A complex is modulated by its association with proliferating cell nuclear antigen. Isabelle Frouin, Magali Toueille, Elena Ferrari, Igor V Shevelev, Ulrich Hübscher Nucleic acids research 2005 pols set
DNA polymerase lambda protects mouse fibroblasts against oxidative DNA damage and is recruited to sites of DNA damage/repair. Elena K Braithwaite, Padmini S Kedar, Li Lan, Yaroslava Y Polosina, Kenjiro Asagoshi, Vladimir P Poltoratsky, Julie K Horton, Holly Miller, George W Teebor, Akira Yasui, Samuel H Wilson The Journal of biological chemistry 2005 new
(+)-Myristinin A, a naturally occurring DNA polymerase beta inhibitor and potent DNA-damaging agent. David J Maloney, Jing-Zhen Deng, Shelley R Starck, Zhijie Gao, Sidney M Hecht Journal of the American Chemical Society 2005 new
In vitro synthesis of uniform poly(dG)-poly(dC) by Klenow exo- fragment of polymerase I. Alexander B Kotlyar, Natalia Borovok, Tatiana Molotsky, Ludmila Fadeev, Michael Gozin Nucleic acids research 2005 partial results
Synthesis, anti-HIV activity, and metabolic stability of new alkenyldiarylmethane HIV-1 non-nucleoside reverse transcriptase inhibitors. Bo-Liang Deng, Tracy L Hartman, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Phillip E Fanwick, Mark Cushman Journal of medicinal chemistry 2005 pols set
Nuclear distribution and chromatin association of DNA polymerase alpha-primase is affected by TEV protease cleavage of Cdc23 (Mcm10) in fission yeast. Xiaowen Yang, Juraj Gregan, Karola Lindner, Hedi Young, Stephen E Kearsey BMC Mol Biol 2005 new
Cytochrome oxidase deficiency protects Escherichia coli from cell death but not from filamentation due to thymine deficiency or DNA polymerase inactivation. Bernard Strauss, Kemba Kelly, Damian Ekiert J Bacteriol 2005 new
Structural analysis of catechin derivatives as mammalian DNA polymerase inhibitors. Yoshiyuki Mizushina, Akiko Saito, Akira Tanaka, Noriyuki Nakajima, Isoko Kuriyama, Masaharu Takemura, Toshifumi Takeuchi, Fumio Sugawara, Hiromi Yoshida Biochem Biophys Res Commun 2005 pols set
Inhibition of the herpes simplex virus type 1 DNA polymerase induces hyperphosphorylation of replication protein A and its accumulation at S-phase-specific sites of DNA damage during infection. Dianna E Wilkinson, Sandra K Weller J Virol 2005 new
Enhanced activity of DNA polymerase iota in mouse brain cells is associated with aggressiveness. Leonid V Gening, A A Kamensky, N G Levitskaya, A N Petrochenkov, I I Poletaeva, Vyacheslav Z Tarantul Biochemistry (Mosc) 2005 new
DNA polymerase lambda mediates a back-up base excision repair activity in extracts of mouse embryonic fibroblasts. Elena K Braithwaite, Rajendra Prasad, David D Shock, Esther W Hou, William A Beard, Samuel H Wilson The Journal of biological chemistry 2005 pols set
Detection of Epstein-Barr virus BGLF4 protein kinase in virus replication compartments and virus particles. Jiin-Tarng Wang, Pei-Wen Yang, Chung-Pei Lee, Chia-Hong Han, Ching-Hwa Tsai, Mei-Ru Chen The Journal of general virology 2005 new
Exploration of factors driving incorporation of unnatural dNTPS into DNA by Klenow fragment (DNA polymerase I) and DNA polymerase alpha. Kristi Kincaid, Jeff W Beckman, Aleksandra Zivkovic, Randall L Halcomb, Joachim W Engels, Robert D Kuchta Nucleic acids research 2005 pols set
Frequent mutation related with overexpression of DNA polymerase beta in primary tumors and precancerous lesions of human stomach. Xiao-Hui Tan, Min Zhao, Kai-Feng Pan, Ying Dong, Bin Dong, Gui-Jian Feng, Guang Jia, You-Yong Lu Cancer Lett 2005 new
Contribution of polar residues of the J-helix in the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I (Klenow fragment): Q677 regulates the removal of terminal mismatch. Kamalendra Singh, Mukund J Modak Biochemistry 2005 partial results
Dipeptide alcohol-based inhibitors of eukaryotic DNA polymerase alpha. Isoko Kuriyama, Naoki Asano, Ikunoshin Kato, Kyoji Ikeda, Masaharu Takemura, Hiromi Yoshida, Kengo Sakaguchi, Yoshiyuki Mizushina Bioorg Med Chem 2005 new
Use of viscogens, dNTPalphaS, and rhodium(III) as probes in stopped-flow experiments to obtain new evidence for the mechanism of catalysis by DNA polymerase beta. Marina Bakhtina, Soojin Lee, Yu Wang, Chris Dunlap, Brandon J Lamarche, Ming-Daw Tsai Biochemistry 2005 new
FGF2-induced upregulation of DNA polymerase-delta p12 subunit in endothelial cells. Patrizia Dell'Era, Stefania Nicoli, Giuseppe Peri, Mariella Nieddu, Maria Grazia Ennas, Marco Presta Oncogene 2005 pols set
Mutability of DNA polymerase I: implications for the creation of mutant DNA polymerases. Ern Loh, Lawrence A Loeb DNA repair 2005 new
Biochemical evidence for the requirement of Hoogsteen base pairing for replication by human DNA polymerase iota. Robert E Johnson, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2005 pols set
Structure of the functional domain of phi29 replication organizer: insights into oligomerization and dna binding. Juan Luis Asensio, Armando Albert, Daniel Muñoz-Espín, Carlos Gonzalez, Juan Hermoso, Laurentino Villar, Jesús Jiménez-Barbero, Margarita Salas, Wilfried J J Meijer The Journal of biological chemistry 2005 pols set
Adduct size limits efficient and error-free bypass across bulky N2-guanine DNA lesions by human DNA polymerase eta. Jeong-Yun Choi, F Peter Guengerich Journal of molecular biology 2005 pols set
Bumps in the road: how replicative DNA polymerases see DNA damage. Matthew Hogg, Susan S Wallace, Sylvie Doublié Current opinion in structural biology 2005 complete Sylvie Doublié*
Inhibitory effect of conjugated eicosapentaenoic acid on mammalian DNA polymerase and topoisomerase activities and human cancer cell proliferation. Yuko Yonezawa, Takahiko Hada, Keisuke Uryu, Tsuyoshi Tsuzuki, Takahiro Eitsuka, Teruo Miyazawa, Chikako Murakami-Nakai, Hiromi Yoshida, Yoshiyuki Mizushina Biochem Pharmacol 2005 pols set
Distinct mechanisms of cis-syn thymine dimer bypass by Dpo4 and DNA polymerase eta. Robert E Johnson, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2005 topics set
(+)-Myristinins A and D from Knema elegans, which inhibit DNA polymerase beta and cleave DNA. Jing-Zhen Deng, Shelley R Starck, Shisheng Li, Sidney M Hecht J Nat Prod 2005 new
Novel PCR-mediated mutagenesis employing DNA containing a natural abasic site as a template and translesional Taq DNA polymerase. Atsushi Kobayashi, Motomitsu Kitaoka, Kiyoshi Hayashi J Biotechnol 2005 pols set
Susceptibilities of several clinical varicella-zoster virus (VZV) isolates and drug-resistant VZV strains to bicyclic furano pyrimidine nucleosides. Graciela Andrei, Rebecca Sienaert, Chris McGuigan, Erik De Clercq, Jan Balzarini, Robert Snoeck Antimicrobial agents and chemotherapy 2005 new
Crystal structures of an intein from the split dnaE gene of Synechocystis sp. PCC6803 reveal the catalytic model without the penultimate histidine and the mechanism of zinc ion inhibition of protein splicing. Ping Sun, Sheng Ye, Sebastien Ferrandon, Thomas C Evans, Ming-Qun Xu, Zihe Rao Journal of molecular biology 2005 topics set
Genetic and physical interactions between Schizosaccharomyces pombe Mcl1 and Rad2, Dna2 and DNA polymerase alpha: evidence for a multifunctional role of Mcl1 in DNA replication and repair. Yasuhiro Tsutsui, Takashi Morishita, Toyoaki Natsume, Kentaro Yamashita, Hiroshi Iwasaki, Fumiaki Yamao, Hideo Shinagawa Curr Genet 2005 new
Site-directed mutagenesis using Pfu DNA polymerase and T4 DNA ligase. Yair Adereth, Kristen J Champion, Tien Hsu, Vincent Dammai BioTechniques 2005 pols set
Consequences of mutations in human DNA polymerase gamma. Matthew J Longley, Maria A Graziewicz, Rachelle J Bienstock, William C Copeland Gene 2005 pols set
Improving the safety of a conditional-live human immunodeficiency virus type 1 vaccine by controlling both gene expression and cell entry. Atze T Das, Chris E Baldwin, Monique Vink, Ben Berkhout J Virol 2005 new
The human stress-activated protein kin17 belongs to the multiprotein DNA replication complex and associates in vivo with mammalian replication origins. Laurent Miccoli, Isabelle Frouin, Olivia Novac, Domenic Di Paola, Francis Harper, Maria Zannis-Hadjopoulos, Giovanni Maga, Denis S F Biard, Jaime F Angulo Molecular and cellular biology 2005 new
Diketo hexenoic acid derivatives are novel selective non-nucleoside inhibitors of mammalian terminal deoxynucleotidyl transferases, with potent cytotoxic effect against leukemic cells. Giada A Locatelli, Roberto Di Santo, Emmanuele Crespan, Roberta Costi, Alessandra Roux, Ulrich Hübscher, Igor V Shevelev, Giuseppina Blanca, Giuseppe Villani, Silvio Spadari, Giovanni Maga Molecular pharmacology 2005 new
The molecular basis of resilience to the effect of the Lys103Asn mutation in non-nucleoside HIV-1 reverse transcriptase inhibitors studied by targeted molecular dynamics simulations. Fátima Rodríguez-Barrios, Jan Balzarini, Federico Gago Journal of the American Chemical Society 2005 pols set
Adaptation to DNA damage and stimulation of genetic instability: the double-edged sword mammalian DNA polymerase kappa. Clarisse Bavoux, Jean-Sébastien Hoffmann, Christophe Cazaux Biochimie 2005 new
Base selectivity is impaired by mutants that perturb hydrogen bonding networks in the RB69 DNA polymerase active site. Guangwei Yang, Jianhong Wang, William H Konigsberg Biochemistry 2005 complete
A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining. Stephanie A Nick McElhinny, Jody M Havener, Miguel Garcia-Diaz, Raquel Juárez, Katarzyna Bebenek, Barbara L Kee, Luis Blanco, Thomas A Kunkel, Dale A Ramsden Molecular cell 2005 new
The role of Thr139 in the human immunodeficiency virus type 1 reverse transcriptase sensitivity to (+)-calanolide A. Joeri Auwerx, Fátima Rodríguez-Barrios, F Ceccherini-Silberstein, Ana San-Félix, Sonsoles Velázquez, Erik De Clercq, María-José Camarasa, CF Perno, Federico Gago, Jan Balzarini Molecular pharmacology 2005 pols set
First synthesis and evaluation of the inhibitory effects of aza analogues of TSAO on HIV-1 replication. Albert Nguyen Van Nhien, Cyrille Tomassi, Christophe Len, José Luis Marco-Contelles, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Denis Postel Journal of medicinal chemistry 2005 pols set
Resistance of human immunodeficiency virus type 1 to the high-mannose binding agents cyanovirin N and concanavalin A. Myriam Witvrouw, Valery Fikkert, Anke Hantson, Christophe Pannecouque, Barry R O'keefe, James McMahon, Leonidas Stamatatos, Erik De Clercq, Anders Bolmstedt Journal of virology 2005 pols set
Effects of substitutions of arginine residues on the basic surface of herpes simplex virus UL42 support a role for DNA binding in processive DNA synthesis. John C W Randell, Gloria Komazin, Changying Jiang, Charles B C Hwang, Donald M Coen Journal of virology 2005 new
(E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU). Erik De Clercq Medicinal research reviews 2005 new
Suppression of RNA interference by adenovirus virus-associated RNA. M Gunnar Andersson, P C Joost Haasnoot, Ning Xu, Saideh Berenjian, Ben Berkhout, Göran Akusjärvi J Virol 2005 new
Non-nucleoside HIV reverse transcriptase inhibitors, Part 6[1]: synthesis and anti-HIV activity of novel 2-[(arylcarbonylmethyl)thio]-6-arylthio DABO analogues. Guang-Fu Sun, Yun-Yan Kuang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Archiv der Pharmazie 2005 pols set
Differential DNA recognition and cleavage by EcoRI dependent on the dynamic equilibrium between the two forms of the malondialdehyde-deoxyguanosine adduct. Laurie A VanderVeen, Alexandra Druckova, James N Riggins, Jennifer L Sorrells, F Peter Guengerich, Lawrence J Marnett Biochemistry 2005 new
Use of modified flap structures for study of base excision repair proteins. Zh K Nazarkina, Dmitriy V Pyshnyi, I A Pyshnaya, Olga I Lavrik, Svetlana N Khodyreva Biochemistry. Biokhimii͡a 2005 new
Substitutions in the Reverse Transcriptase and Protease Genes of HIV-1 Subtype B in Untreated Individuals and Patients Treated With Antiretroviral Drugs. Dan Turner, Bluma G Brenner, Daniela D Moisi, Chen Liang, Mark A. Wainberg Journal of the International AIDS Society 2005 pols set
Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta. Toshiki Tsurimoto, Ayako Shinozaki, Masaki Yano, Masayuki Seki, Takemi Enomoto Genes Cells 2005 pols set
Challenges for the clinical development of new nucleoside reverse transcriptase inhibitors for HIV infection. Mark A. Wainberg, James P C Sawyer, Julio S G Montaner, Robert L Murphy, Daniel R Kuritzkes, Francois Raffi Antiviral therapy 2005 pols set
Processivity factor of KSHV contains a nuclear localization signal and binding domains for transporting viral DNA polymerase into the nucleus. Yali Chen, Mihai Ciustea, Robert P Ricciardi Virology 2005 new
A single domain in human DNA polymerase iota mediates interaction with PCNA: implications for translesion DNA synthesis. Lajos Haracska, Narottam Acharya, Ildiko Unk, Robert E Johnson, Jerard Hurwitz, Louise Prakash, Satya Prakash Molecular and cellular biology 2005 pols set
High mobility of flap endonuclease 1 and DNA polymerase eta associated with replication foci in mammalian S-phase nucleus. Lioudmila Solovjeva, Maria Svetlova, Lioudmila Sasina, Kyoji Tanaka, Masafumi Saijo, Igor Nazarov, Morton Bradbury, Nikolai Tomilin Mol Biol Cell 2005 new
A lysine residue in the fingers subdomain of T7 DNA polymerase modulates the miscoding potential of 8-oxo-7,8-dihydroguanosine. Luis G Brieba, Robert J Kokoska, Katarzyna Bebenek, Thomas A Kunkel, Tom Ellenberger Structure (London, England : 1993) 2005 topics set
Expansion of repertoire of modified DNAs prepared by PCR using KOD Dash DNA polymerase. Tsutomu Ohbayashi, Masayasu Kuwahara, Masatoshi Hasegawa, Toshiyuki Kasamatsu, Takehiro Tamura, Hiroaki Sawai Org Biomol Chem 2005 new
Genetic analysis of two Arabidopsis DNA polymerase epsilon subunits during early embryogenesis. Arnaud Ronceret, Jocelyne Guilleminot, Frédéric Lincker, Jose Gadea-Vacas, Valérie Delorme, Nicole Bechtold, Georges Pelletier, Michel Delseny, Marie-Edith Chabouté, Martine Devic Plant J 2005 new
Monoacetylcurcumin: a new inhibitor of eukaryotic DNA polymerase lambda and a new ligand for inhibitor-affinity chromatography. Yoshiyuki Mizushina, Tomomi Ishidoh, Toshifumi Takeuchi, Noriko Shimazaki, Osamu Koiwai, Kouji Kuramochi, Susumu Kobayashi, Fumio Sugawara, Kengo Sakaguchi, Hiromi Yoshida Biochem Biophys Res Commun 2005 new
Sequence determination of nucleic acids containing 5-methylisocytosine and isoguanine: identification and insight into polymerase replication of the non-natural nucleobases. J David Ahle, Stephen Barr, A Michael Chin, Thomas R Battersby Nucleic acids research 2005 topics set
Inhibitory effect of dipeptide alcohol derivatives containing mercapto group on eukaryotic DNA polymerase alpha. Ikunoshin Kato, Isoko Kuriyama, Naoki Asano, Kyoko Ikeda, Hiromi Yoshida, Yoshiyuki Mizushina International journal of molecular medicine 2005 new
Interaction between the T4 helicase-loading protein (gp59) and the DNA polymerase (gp43): a locking mechanism to delay replication during replisome assembly. Jun Xi, Zhihao Zhuang, Zhiquan Zhang, Tzvia Selzer, Michelle M Spiering, Gordon G Hammes, Stephen J Benkovic Biochemistry 2005 new
Crystal structure and functional implications of Pyrococcus furiosus hef helicase domain involved in branched DNA processing. Tatsuya Nishino, Kayoko Komori, Daisuke Tsuchiya, Yoshizumi Ishino, Kosuke Morikawa Structure (London, England : 1993) 2005 new
A homogeneous, high-throughput fluorescence resonance energy transfer-based DNA polymerase assay. Adam Shapiro, Olga Rivin, Ning Gao, Laurel Hajec Anal Biochem 2005 new
Sulfoquinovosylmonoacylglycerol inhibitory mode analysis of rat DNA polymerase beta. Nobuyuki Kasai, Yoshiyuki Mizushina, Hiroshi Murata, Takayuki Yamazaki, Tadayasu Ohkubo, Kengo Sakaguchi, Fumio Sugawara FEBS J 2005 pols set
CAG repeat polymorphism in the DNA polymerase gamma gene in a Polish population: an association with testicular cancer risk. R Nowak, R Zub, I Skoneczna, K Sikora, M Ligaj Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005 new
DNA polymerase lambda directly binds to proliferating cell nuclear antigen through its confined C-terminal region. Noriko Shimazaki, Takaya Yazaki, Takashi Kubota, Asami Sato, Ayako Nakamura, Shunsuke Kurei, Shingo Toji, Katsuyuki Tamai, Osamu Koiwai Genes Cells 2005 new
Addendum: Site-directed mutagenesis using Pfu DNA polymerase and T4 DNA ligase. BioTechniques 2005 pols set
Error-prone translesion synthesis by human DNA polymerase eta on DNA-containing deoxyadenosine adducts of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene. Dominic Chiapperino, Mangmang Cai, Jane M Sayer, Haruhiko Yagi, Heiko Kroth, Chikahide Masutani, Fumio Hanaoka, Donald M Jerina, Albert M Cheh The Journal of biological chemistry 2005 pols set
Fluorous base-pairing effects in a DNA polymerase active site. Jacob S Lai, Eric T Kool Chemistry 2005 new
Fidelity discrimination in DNA polymerase beta: differing closing profiles for a mismatched (G:A) versus matched (G:C) base pair. Ravi Radhakrishnan, Tamar Schlick Journal of the American Chemical Society 2005 new
XRCC1 and DNA polymerase beta interaction contributes to cellular alkylating-agent resistance and single-strand break repair. Heng-Kuan Wong, David M Wilson J Cell Biochem 2005 new
A method for filling in the cohesive ends of double-stranded DNA using Pfu DNA polymerase. Shaohui Yang, Xincang Li, Dongfeng Ding, Jianhua Hou, Zhaoxia Jin, Xinchun Yu, Tao Bo, Weidong Li, Minggang Li Biotechnol Appl Biochem 2005 pols set
Comparison of functional properties of mammalian DNA polymerase lambda and DNA polymerase beta in reactions of DNA synthesis related to DNA repair. Natalia A Lebedeva, Nadejda I Rechkunova, Sergey V Dezhurov, Svetlana N Khodyreva, Alain Favre, Luis Blanco, Olga I Lavrik Biochimica et biophysica acta 2005 pols set
MSH2-MSH6 stimulates DNA polymerase eta, suggesting a role for A:T mutations in antibody genes. Teresa M Wilson, Alexandra Vaisman, Stella A Martomo, Patsa Sullivan, Li Lan, Fumio Hanaoka, Akira Yasui, Roger Woodgate, Patricia J Gearhart J Exp Med 2005 new
Synthesis of novel poly(dG)-poly(dG)-poly(dC) triplex structure by Klenow exo- fragment of DNA polymerase I. Alexander B Kotlyar, Natalia Borovok, Tatiana Molotsky, Dmitry Klinov, Benjamin Dwir, Eli Kapon Nucleic acids research 2005 partial results
Nucleotide sequence and phylogenetic analyses of the DNA polymerase gene of Anticarsia gemmatalis nucleopolyhedrovirus. Caren Cristina Dalmolin, Felipe R da Silva, Luciane V Mello, Daniel J Rigden, Maria Elita B Castro Virus Res 2005 new
Crystallography and the design of anti-AIDS drugs: conformational flexibility and positional adaptability are important in the design of non-nucleoside HIV-1 reverse transcriptase inhibitors. Kalyan Das, Paul J Lewi, Stephen H Hughes, Edward Arnold Progress in biophysics and molecular biology 2005 pols set
POLG mutations in Alpers syndrome. Khue V Nguyen, E Østergaard, S Holst Ravn, T Balslev, E Rubaek Danielsen, A Vardag, P J McKiernan, G Gray, Robert K Naviaux Neurology 2005 pols set
Expression of DNA polymerase {beta} cancer-associated variants in mouse cells results in cellular transformation. Joann B Sweasy, Tieming Lang, Daniela Starcevic, Ka-Wai Sun, Char-Chang Lai, Daniel Dimaio, Shibani Dalal Proceedings of the National Academy of Sciences of the United States of America 2005 new
Mapping the interaction of DNA with the Escherichia coli DNA polymerase clamp loader complex. Eric R Goedken, Steven L Kazmirski, Gregory D Bowman, Mike E O'Donnell, John Kuriyan Nature structural & molecular biology 2005 pols set
DNA elongation by the human DNA polymerase lambda polymerase and terminal transferase activities are differentially coordinated by proliferating cell nuclear antigen and replication protein A. Giovanni Maga, Kristijan Ramadan, Giada A Locatelli, Igor V Shevelev, Silvio Spadari, Ulrich Hübscher The Journal of biological chemistry 2005 pols set
Human DNA polymerase iota promotes replication through a ring-closed minor-groove adduct that adopts a syn conformation in DNA. William T Wolfle, Robert E Johnson, Irina G Minko, R Stephen Lloyd, Satya Prakash, Louise Prakash Molecular and cellular biology 2005 pols set
Structural analysis of isosteviol and related compounds as DNA polymerase and DNA topoisomerase inhibitors. Yoshiyuki Mizushina, Toshihiro Akihisa, Motohiko Ukiya, Yusuke Hamasaki, Chikako Murakami-Nakai, Isoko Kuriyama, Toshifumi Takeuchi, Fumio Sugawara, Hiromi Yoshida Life Sci 2005 pols set
Lyase activities intrinsic to Escherichia coli polymerases IV and V. Xuan Shen, Roger Woodgate, Myron F Goodman DNA repair 2005 pols set
Transcriptional regulation of the Drosophila orc2 gene by the DREF pathway. Koji Okudaira, Katsuhito Ohno, Hideki Yoshida, Maki Asano, Fumiko Hirose, Masamitsu Yamaguchi Biochimica et biophysica acta 2005 new
TSAO derivatives the first non-peptide inhibitors of HIV-1 RT dimerization. María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez Antiviral chemistry & chemotherapy 2005 pols set
Surface-initiated growth of poly d(A-T) by Taq DNA polymerase. Young Shik Chi, Young Hwan Jung, Insung S Choi, Yang-Gyun Kim Langmuir 2005 pols set
Nucleotide analogues as probes for DNA polymerases. K-H Jung, Andreas Marx Cellular and molecular life sciences : CMLS 2005 new
A novel approach for inhibition of HIV-1 by RNA interference: counteracting viral escape with a second generation of siRNAs. Olivier Ter Brake, Ben Berkhout J RNAi Gene Silencing 2005 new
Biological characterization of novel inhibitors of the gram-positive DNA polymerase IIIC enzyme. Alexander Kuhl, Niels Svenstrup, Christoph Ladel, Michael Otteneder, Annegret Binas, Guido Schiffer, Michael Brands, Thomas Lampe, Karl Ziegelbauer, Helga Rübsamen-Waigmann, Dieter Haebich, Kerstin Ehlert Antimicrob Agents Chemother 2005 new
Reconstitution of a minimal DNA replicase from Pseudomonas aeruginosa and stimulation by non-cognate auxiliary factors. Thale C Jarvis, Amber A Beaudry, James M Bullard, Nebojsa Janjic, Charles S McHenry The Journal of biological chemistry 2005 pols set
Discovery and characterization of the cryptic psi subunit of the pseudomonad DNA replicase. Thale C Jarvis, Amber A Beaudry, James M Bullard, Urs Ochsner, H Garry Dallmann, Charles S McHenry The Journal of biological chemistry 2005 pols set
Computer simulations of protein functions: searching for the molecular origin of the replication fidelity of DNA polymerases. Jan Florián, Myron F Goodman, Arieh Warshel Proceedings of the National Academy of Sciences of the United States of America 2005 new
4'C-ethynyl-thymidine acts as a chain terminator during DNA-synthesis catalyzed by HIV-1 reverse transcriptase. Daniel Summerer, Andreas Marx Bioorganic & medicinal chemistry letters 2005 pols set
Critical role of R-loops in processing replication blocks. Manel Camps, Lawrence A Loeb Frontiers in bioscience : a journal and virtual library 2005 new
Mechanism of inhibition of vaccinia virus DNA polymerase by cidofovir diphosphate. Wendy C Magee, Karl Y Hostetler, David H Evans Antimicrob Agents Chemother 2005 complete David H Evans*
DNA polymerase eta contributes to strand bias of mutations of A versus T in immunoglobulin genes. Vladimir I Mayorov, Igor B Rogozin, Linda R Adkison, Patricia J Gearhart J Immunol 2005 new
Tuning single nucleotide discrimination in polymerase chain reactions (PCRs): synthesis of primer probes bearing polar 4'-C-modifications and their application in allele-specific PCR. Jens Gaster, Andreas Marx Chemistry (Weinheim an der Bergstrasse, Germany) 2005 new
Efficient isothermal expansion of human telomeric and minisatellite repeats by Thermococcus litoralis DNA polymerase. Jörg S Hartig, Eric T Kool Nucleic acids research 2005 pols set
Usefulness of repeated GenomiPhi, a phi29 DNA polymerase-based rolling circle amplification kit, for generation of large amounts of plasmid DNA. Masahiro Sato, Masato Ohtsuka, Yuhsuke Ohmi Biomol Eng 2005 pols set
Correction of X-ray intensities from single crystals containing lattice-translocation defects. Jianhong Wang, Satwik Kamtekar, Andrea J Berman, Thomas A Steitz Acta Crystallogr D Biol Crystallogr 2005 topics set
Retroviral superinfection resistance. Micha Nethe, Ben Berkhout, Antoinette C van der Kuyl Retrovirology 2005 new
Acidic residues in the nucleotide-binding site of the bacteriophage T7 DNA primase. Seung-Joo Lee, Charles C Richardson The Journal of biological chemistry 2005 pols set
Low variability of the POLG (CAG)n repeat in north Eurasian populations. Boris A Malyarchuk, Marta Papuga, Tomasz Grzybowski, Igor B Rogozin, Marcin Wozniak, Miroslava V Derenko, Serge Yu Rychkov, Jakub Czarny, Ilia A Zakharov, Danuta Miścicka-Sliwka Human biology 2005 new
Cell-free cloning using phi29 DNA polymerase. Clyde A Hutchison, Hamilton O Smith, Cynthia Pfannkoch, J Craig Venter Proceedings of the National Academy of Sciences of the United States of America 2005 pols set
Comparison of DNA polymerase activities between recombinant feline immunodeficiency and leukemia virus reverse transcriptases. Darwin J Operario, Holly M Reynolds, Baek Kim Virology 2005 partial results
[Isolation and characterization of the thermostable DNA polymerase of the hyperthermophilic archaeum Thermococcus litoralis Sh1AM] Prikladnaia biokhimiia i mikrobiologiia 2005 topics set
HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome. Ellen M Westerhout, Marcel Ooms, Monique Vink, Atze T Das, Ben Berkhout Nucleic acids research 2005 new
Mammalian mitotic centromere-associated kinesin (MCAK): a new molecular target of sulfoquinovosylacylglycerols novel antitumor and immunosuppressive agents. Satoko Aoki, Keisuke Ohta, Takayuki Yamazaki, Fumio Sugawara, Kengo Sakaguchi The FEBS journal 2005 new
Plastid DNA polymerases from higher plants, Arabidopsis thaliana. Yoko Mori, Seisuke Kimura, Ai Saotome, Nobuyuki Kasai, Norihiro Sakaguchi, Yukinobu Uchiyama, Toyotaka Ishibashi, Taichi Yamamoto, Hiroyuki Chiku, Kengo Sakaguchi Biochemical and biophysical research communications 2005 new
Selective inhibitors of terminal deoxyribonucleotidyltransferase (TdT): baicalin and genistin. Yukinobu Uchiyama, Junko Tagami, Shinji Kamisuki, Nobuyuki Kasai, Masahiko Oshige, Hiroyuki Chiku, Siroh Ibe, Osamu Koiwai, Fumio Sugawara, Kengo Sakaguchi Biochimica et biophysica acta 2005 new
Incorporation of non-nucleoside triphosphate analogues opposite to an abasic site by human DNA polymerases beta and lambda. Emmanuele Crespan, Samantha Zanoli, Anastasiya Khandazhinskaya, Igor V Shevelev, Maxim Jasko, Ludmila Alexandrova, Marina Kukhanova, Giuseppina Blanca, Giuseppe Villani, Ulrich Hübscher, Silvio Spadari, Giovanni Maga Nucleic acids research 2005 pols set
The discovery of RNA polymerase. Jerard Hurwitz The Journal of biological chemistry 2005 topics set
A macroscopic kinetic model for DNA polymerase elongation and high-fidelity nucleotide selection. Steve Viljoen, Mark A Griep, Michael Nelson, Hendrik Viljoen Comput Biol Chem 2005 complete Hendrik Viljoen*
[Role of DNA polymerase a in genome stability]. Atsuko Niimi, Siripan Limusirichaikul, Motoshi Suzuki Seikagaku. The Journal of Japanese Biochemical Society 2005 new
Infantile hepatocerebral syndromes associated with mutations in the mitochondrial DNA polymerase-gammaA. Gianfrancesco Ferrari, Eleonora Lamantea, Alice Donati, Massimiliano Filosto, Egill Briem, Franco Carrara, Rossella Parini, Alessandro Simonati, René Santer, Massimo Zeviani Brain : a journal of neurology 2005 pols set
Sulfo-quinovosyl-acyl-glycerol (SQAG), a eukaryotic DNA polymerase inhibitor and anti-cancer agent. Yoshiyuki Mizushina, Nobuyuki Kasai, Hiroshi Iijima, Fumio Sugawara, Hiromi Yoshida, Kengo Sakaguchi Curr Med Chem Anticancer Agents 2005 new
Long-patch base excision DNA repair of 2-deoxyribonolactone prevents the formation of DNA-protein cross-links with DNA polymerase beta. Jung-Suk Sung, Michael S DeMott, Bruce Demple The Journal of biological chemistry 2005 new
Processivity clamp gp45 and ssDNA-binding-protein gp32 modulate the fidelity of bacteriophage RB69 DNA polymerase in a sequence-specific manner, sometimes enhancing and sometimes compromising accuracy. Anna Bebenek, Geraldine T Carver, Farid A Kadyrov, Grace E Kissling, John W Drake Genetics 2005 complete
Evidence of genetic variability of human immunodeficiency virus type 1 in plasma and cervicovaginal lavage in ethiopian women seeking care for sexually transmitted infections. Melaku Adal, Workenesh Ayele, Dawit Wolday, Kifle Dagne, Tsehaynesh Messele, Tesfaye Tilahun, Ben Berkhout, Shlomo Mayaan, Georgios Pollakis, Wendelien Dorigo-Zetsma AIDS Res Hum Retroviruses 2005 new
Different mutation signatures in DNA polymerase eta- and MSH6-deficient mice suggest separate roles in antibody diversification. Stella A Martomo, William W Yang, Robert P Wersto, Tsuyoshi Ohkumo, Yuji Kondo, Masayuki Yokoi, Chikahide Masutani, Fumio Hanaoka, Patricia J Gearhart Proceedings of the National Academy of Sciences of the United States of America 2005 new
Alterations of DNA and chromatin structures at telomeres and genetic instability in mouse cells defective in DNA polymerase alpha. Mirai Nakamura, Akira Nabetani, Takeshi Mizuno, Fumio Hanaoka, Fuyuki Ishikawa Molecular and cellular biology 2005 new
The screening of expression and purification conditions for replicative DNA polymerase associated B-subunits, assignment of the exonuclease activity to the C-terminus of archaeal pol D DP1 subunit. Maarit Jokela, Mari Raki, Kaisa Heikkinen, Katri Sepponen, Anitta Eskelinen, Juhani E Syväoja Protein Expr Purif 2005 new
8-oxoguanine incorporation into DNA repeats in vitro and mismatch recognition by MutSalpha. Peter Macpherson, Flavia Barone, Giovanni Maga, Filomena Mazzei, Peter Karran, Margherita Bignami Nucleic acids research 2005 new
Human cytomegalovirus uracil DNA glycosylase associates with ppUL44 and accelerates the accumulation of viral DNA. Mark N Prichard, Heather Lawlor, Gregory M Duke, Chengjun Mo, Zhengqiang Wang, Melissa Dixon, George Kemble, Earl R Kern Virology journal 2005 new
Poly(ADP-ribose) polymerase activity prevents signaling pathways for cell cycle arrest after DNA methylating agent exposure. Julie K Horton, Donna F Stefanick, Jana M Naron, Padmini S Kedar, Samuel H Wilson The Journal of biological chemistry 2005 new
Histone deposition protein Asf1 maintains DNA replisome integrity and interacts with replication factor C. AlexaA Franco, WendyM Lam, PeterM Burgers, PaulD Kaufman Genes & development 2005 new
Deoxythreosyl phosphonate nucleosides as selective anti-HIV agents. Tongfei Wu, Matheus Froeyen, Veerle Kempeneers, Christophe Pannecouque, Jing Wang, Roger Busson, Erik De Clercq, Piet Herdewijn Journal of the American Chemical Society 2005 pols set
A novel pancoronavirus RT-PCR assay: frequent detection of human coronavirus NL63 in children hospitalized with respiratory tract infections in Belgium. Elien Moës, Leen Vijgen, Els Keyaerts, Kalina Zlateva, Sandra Li, Piet Maes, Krzysztof Pyrc, Ben Berkhout, Lia van der Hoek, Marc Van Ranst BMC Infect Dis 2005 new
Involvement of poly(ADP-ribose) polymerase activity in regulating Chk1-dependent apoptotic cell death. Julie K Horton, Donna F Stefanick, Samuel H Wilson DNA repair 2005 new
Bone mesenchymal stem cells transplanted into rabbit intervertebral discs can increase proteoglycans. Yin-Gang Zhang, Xiong Guo, Peng Xu, Long-Li Kang, Jinming Li Clinical orthopaedics and related research 2005 new
Analysis of single nucleotide incorporation reactions by capillary electrophoresis. Jeremiah W Hanes, Kenneth A Johnson Analytical biochemistry 2005 new
Synthesis of oligonucleotides bearing an arylamine modification in the C8-position of 2'-deoxyguanosine. C Meier, S Gräsl, Ilka Detmer, Andreas Marx Nucleosides, nucleotides & nucleic acids 2005 new
Attenuation of DNA replication by HIV-1 reverse transcriptase near the central termination sequence. Michael E Ignatov, Anthony J Berdis, Stuart F J Le Grice, Mary D Barkley Biochemistry 2005 pols set
A novel PDIP1-related protein, KCTD10, that interacts with proliferating cell nuclear antigen and DNA polymerase delta. Jianlin Zhou, Kaiqun Ren, Xin Liu, Xiwen Xiong, Xiaoxiao Hu, Jian Zhang Biochimica et biophysica acta 2005 new
The hydrophobic hinge region of rat DNA polymerase beta is critical for substrate binding pocket geometry. Daniela Starcevic, Shibani Dalal, Joachim Jaeger, Joann B Sweasy The Journal of biological chemistry 2005 new
Portraits of a Y-family DNA polymerase. Wei Wen Yang FEBS letters 2005 topics set
How are specialized (low-fidelity) eukaryotic polymerases selected and switched with high-fidelity polymerases during translesion DNA synthesis? Paula L Fischhaber, Errol C Friedberg DNA repair 2005 topics set
A specific subdomain in phi29 DNA polymerase confers both processivity and strand-displacement capacity. Irene Rodríguez, José María Lázaro, Luis Blanco, Satwik Kamtekar, Andrea J Berman, Jianhong Wang, Thomas A Steitz, Margarita Salas, Miguel de Vega Proceedings of the National Academy of Sciences of the United States of America 2005 partial results
It's the virus, stupid--part 2. Ben Berkhout Retrovirology 2005 new
Syn-full behavior by T7 DNA polymerase. William A Beard, Samuel H Wilson Structure (London, England : 1993) 2005 pols set
Emerging anti-HIV drugs. Erik De Clercq Expert Opin Emerg Drugs 2005 topics set
Comparison of single regulated lentiviral vectors with rtTA expression driven by an autoregulatory loop or a constitutive promoter. David Markusic, Ronald Oude-Elferink, Atze T Das, Ben Berkhout, Jurgen Seppen Nucleic acids research 2005 new
Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones. Scott R Budihas, Inna Gorshkova, Sergei A Gaidamakov, Antony Wamiru, Marion K Bona, Michael A. Parniak, Robert J Crouch, James B McMahon, John A Beutler, Stuart F J Le Grice Nucleic acids research 2005 new
Impaired rescue of chain-terminated DNA synthesis associated with the L74V mutation in human immunodeficiency virus type 1 reverse transcriptase. Fernando A Frankel, Bruno Marchand, Dan Turner, Matthias Götte, Mark A. Wainberg Antimicrob Agents Chemother 2005 topics set
Enhanced fidelity in mismatch extension by DNA polymerase through directed combinatorial enzyme design. Daniel Summerer, Nicolas Z Rudinger, Ilka Detmer, Andreas Marx Angewandte Chemie (International ed. in English) 2005 new
Base excision repair in nucleosomes lacking histone tails. Brian C Beard, Jill J Stevenson, Samuel H Wilson, Michael J Smerdon DNA repair 2005 new
[Inhibitory effect of hTERT dsRNA on telomerase activity in lung carcinoma cell line A549]. Feng-Jun Tian, Zhi-Yong Wang, Jun-Yi Ma, Yun-Xia Zhao, Wei Lu Ai zheng = Aizheng = Chinese journal of cancer 2005 new
Effective form of sulfoquinovosyldiacyglycerol (SQDG) vesicles for DNA polymerase inhibition. Kenjiro Matsumoto, Hideki Sakai, Ryo Takeuchi, Koji Tsuchiya, Keisuke Ohta, Fumio Sugawara, Masahiko Abe, Kengo Sakaguchi Colloids Surf B Biointerfaces 2005 new
Enzymatic processing of replication and recombination intermediates by the vaccinia virus DNA polymerase. Michael D Hamilton, David H Evans Nucleic acids research 2005 complete David H Evans*
The hyperthermophilic euryarchaeota Pyrococcus abyssi likely requires the two DNA polymerases D and B for DNA replication. Ghislaine Henneke, Didier Flament, Ulrich Hübscher, Joël Querellou, Jean-Paul Raffin Journal of molecular biology 2005 new
Hypersensitivity in DNA mismatch repair-deficient colon carcinoma cells to DNA polymerase reaction inhibitors. Tomonori Takahashi, Zhenghua Min, Iichiro Uchida, Michitsune Arita, Yoh Watanabe, Minoru Koi, Hiromichi Hemmi Cancer Lett 2005 complete Hiromichi Hemmi*
Structural mechanism for coordination of proofreading and polymerase activities in archaeal DNA polymerases. Toshihiro Kuroita, Hiroyoshi Matsumura, Naohiko Yokota, Masao Kitabayashi, Hiroshi Hashimoto, Tsuyoshi Inoue, Tadayuki Imanaka, Yasushi Kai Journal of molecular biology 2005 topics set
The relative roles in vivo of Saccharomyces cerevisiae Pol eta, Pol zeta, Rev1 protein and Pol32 in the bypass and mutation induction of an abasic site, T-T (6-4) photoadduct and T-T cis-syn cyclobutane dimer. Peter E M Gibbs, John P McDonald, Roger Woodgate, Christopher W Lawrence Genetics 2005 pols set
Protein promiscuity: drug resistance and native functions--HIV-1 case. Ariel Fernández, Dan S Tawfik, Ben Berkhout, Rogier W Sanders, Andrzej Kloczkowski, Taner Sen, Bob Jernigan J Biomol Struct Dyn 2005 new
Interactions between the cell cycle and embryonic patterning in Arabidopsis uncovered by a mutation in DNA polymerase epsilon. Pablo D Jenik, Rebecca E J Jurkuta, M Kathryn Barton Plant Cell 2005 complete M Kathryn Barton*
Nucleotide-induced DNA polymerase active site motions accommodating a mutagenic DNA intermediate. Vinod K Batra, William A Beard, David D Shock, Lars C Pedersen, Samuel H Wilson Structure (London, England : 1993) 2005 topics set
Virion instability of human immunodeficiency virus type 1 reverse transcriptase (RT) mutated in the protease cleavage site between RT p51 and the RT RNase H domain. Michael E Abram, Michael A. Parniak Journal of virology 2005 pols set
Trading places: how do DNA polymerases switch during translesion DNA synthesis? Errol C Friedberg, Alan R Lehmann, Robert P P Fuchs Molecular cell 2005 new
Combination of telomerase antisense oligonucleotides simultaneously targeting hTR and hTERT produces synergism of inhibition of telomerase activity and growth in human colon cancer cell line. Xiao-Hua Fu, Jian-Song Zhang, Na Zhang, Yang-De Zhang World journal of gastroenterology : WJG 2005 new
A closed conformation for the Pol lambda catalytic cycle. Miguel Garcia-Diaz, Katarzyna Bebenek, Joseph M Krahn, Thomas A Kunkel, Lars C Pedersen Nature structural & molecular biology 2005 topics set
Analysis of interactions of DNA polymerase beta and reverse transcriptases of human immunodeficiency and mouse leukemia viruses with dNTP analogs containing a modified sugar residue. Natalia A Lebedeva, T A Seredina, V N Silnikov, T V Abramova, A S Levina, Svetlana N Khodyreva, Nadejda I Rechkunova, Olga I Lavrik Biochemistry. Biokhimii͡a 2005 pols set
REV1 mediated mutagenesis in base excision repair deficient mouse fibroblast. Vladimir P Poltoratsky, Julie K Horton, Rajendra Prasad, Samuel H Wilson DNA repair 2005 new
Identification of amino acid residues in the human immunodeficiency virus type-1 reverse transcriptase tryptophan-repeat motif that are required for subunit interaction using infectious virions. Alok Mulky, Stefan G Sarafianos, Yujiang Jia, Edward Arnold, John C Kappes Journal of molecular biology 2005 new
Molecular detection of rabies encephalitis and correlation with cytokine expression. Gerard J Nuovo, Dulcelena L Defaria, Juan G Chanona-Vilchi, Yongqing Zhang Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005 new
Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity. Caterina Fattorusso, Sandra Gemma, Stefania Butini, Paul Huleatt, Bruno Catalanotti, Marco Persico, Meri De Angelis, Isabella Fiorini, Vito Nacci, Anna Ramunno, Manuela Rodriquez, Giovanni Greco, Ettore Novellino, Alberto Bergamini, Stefano Marini, Massimo Coletta, Giovanni Maga, Silvio Spadari, Giuseppe Campiani Journal of medicinal chemistry 2005 pols set
[A novel colorimetric test to study the susceptibility of human cytomegalovirus DNA polymerase to foscarnet]. Alexandra Ducancelle, Sophie Alain, C Scieux, A-M Fillet, Françoise Petit, M-J Sanson-Le Pors, M-C Mazeron Pathol Biol (Paris) 2005 pols set
Herpes simplex virus type 1 DNA polymerase requires the mammalian chaperone hsp90 for proper localization to the nucleus. April D Burch, Sandra K Weller J Virol 2005 new
Characterization of SpPol4, a unique X-family DNA polymerase in Schizosaccharomyces pombe. Sergio González-Barrera, Arancha Sánchez, José F Ruiz, Raquel Juárez, Angel J Picher, Gloria Terrados, Paula Andrade, Luis Blanco Nucleic acids research 2005 topics set
DNA polymerase V and RecA protein, a minimal mutasome. Katharina Schlacher, Kris Leslie, Claire Wyman, Roger Woodgate, Michael M Cox, Myron F Goodman Molecular cell 2005 new
4'-Ethynylstavudine (4'-Ed4T) has potent anti-HIV-1 activity with reduced toxicity and shows a unique activity profile against drug-resistant mutants. Hiromichi Tanaka, Kazuhiro Haraguchi, Hiroki Kumamoto, Masanori Baba, Yung-Chi Cheng Antivir Chem Chemother 2005 new
Inhibition of human immunodeficiency virus type 1 reverse transcriptase, RNase H, and integrase activities by hydroxytropolones. Joël Didierjean, Catherine Isel, Flore Querré, Jean-François Mouscadet, Anne-Marie Aubertin, Jean-Yves Valnot, Serge R Piettre, Roland Marquet Antimicrob Agents Chemother 2005 complete Roland Marquet*
Structure of a high fidelity DNA polymerase bound to a benzo[a]pyrene adduct that blocks replication. Gerald W Hsu, Xuanwei Huang, Natalia P Luneva, Nicholas E Geacintov, Lorena S Beese The Journal of biological chemistry 2005 topics set
BRCA1 interaction with human papillomavirus oncoproteins. Yongqing Zhang, Saijun Fan, Qinghui Meng, Yongxian Ma, Pragati Katiyar, Richard Schlegel, Eliot M Rosen The Journal of biological chemistry 2005 new
Proliferating cell nuclear antigen promotes translesion synthesis by DNA polymerase zeta. Parie Garg, Carrie M W Stith, Jerzy Majka, Peter M J Burgers The Journal of biological chemistry 2005 new
Reiterative template switching: the effect of single-strand homopolymeric DNA on non-template-directed nucleotide addition by DNA polymerase. Allison M Faucett, Angel L Islas Biochem Biophys Res Commun 2005 complete Angel L Islas*
Optimization of on-chip elongation for fabricating double-stranded DNA microarrays. Yunfei Bai, Qinyu Ge, Jinke Wang, Tongxiang Li, Quanjun Liu, Zuhong Lu Colloids and surfaces. B, Biointerfaces 2005 new
A bipartite polymerase-processivity factor interaction: only the internal beta binding site of the alpha subunit is required for processive replication by the DNA polymerase III holoenzyme. Paul R Dohrmann, Charles S McHenry Journal of molecular biology 2005 new
Synthesis of novel diarylpyrimidine analogues and their antiviral activity against human immunodeficiency virus type 1. Jerome Guillemont, Elisabeth Pasquier, Patrice Palandjian, Daniel Vernier, Sandrine Gaurrand, Paul J Lewi, Jan Heeres, Marc R De Jonge, Lucien M H Koymans, Frits F D Daeyaert, Maarten H Vinkers, Edward Arnold, Kalyan Das, Rudi Pauwels, Koen Andries, Marie-Pierre P De Béthune, Eva Bettens, Kurt Hertogs, Piet Wigerinck, Philip Timmerman, Paul A J Janssen Journal of medicinal chemistry 2005 new
An in vivo analysis of the localisation and interactions of human p66 DNA polymerase delta subunit. J Richard G Pohler, Marit Otterlei, Emma Warbrick BMC molecular biology 2005 complete Emma Warbrick*
Proliferating cell nuclear antigen recruits cyclin-dependent kinase inhibitor Xic1 to DNA and couples its proteolysis to DNA polymerase switching. Li-Chiou Chuang, P Renee Yew The Journal of biological chemistry 2005 new
DNA polymerases that propagate the eukaryotic DNA replication fork. Parie Garg, Peter M J Burgers Crit Rev Biochem Mol Biol 2005 new
Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4+ T lymphocytes. Marloes A Naarding, Irene S Ludwig, Fedde Groot, Ben Berkhout, Teunis B H Geijtenbeek, Georgios Pollakis, William A Paxton J Clin Invest 2005 new
Design, synthesis, and SAR of a novel pyrazinone series with non-nucleoside HIV-1 reverse transcriptase inhibitory activity. Jan Heeres, Marc R De Jonge, Lucien M H Koymans, Frits F D Daeyaert, Maarten H Vinkers, Koen J A Van Aken, Edward Arnold, Kalyan Das, Amuri Kilonda, Georges J Hoornaert, Frans Compernolle, Marek Cegla, Rasha A Azzam, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, Paul J Lewi, Paul A J Janssen Journal of medicinal chemistry 2005 pols set
Effect of DNA polymerase beta loop variants on discrimination of O6-methyldeoxyguanosine modification present in the nucleotide versus template substrate. Subarna Hamid, Kristin A Eckert Biochemistry 2005 new
Expression and purification of histidine-tagged bacteriophage T7 DNA polymerase. Marina Schlicke, Susanne Brakmann Protein Expr Purif 2005 pols set
Polymerase mu is up-regulated during the T cell-dependent immune response and its deficiency alters developmental dynamics of spleen centroblasts. Daniel Lucas, Teresa Laín de Lera, Manuel A González, José F Ruiz, Orlando Domínguez, Jesús C Casanova, Carlos Martínez-A, Luis Blanco, Antonio Bernad European journal of immunology 2005 new
A host-guest approach for determining drug-DNA interactions: an example using netropsin. Kristie D Goodwin, Eric C Long, Millie M Georgiadis Nucleic acids research 2005 topics set
Alternative tRNA priming of human immunodeficiency virus type 1 reverse transcription explains sequence variation in the primer-binding site that has been attributed to APOBEC3G activity. Atze T Das, Monique Vink, Ben Berkhout J Virol 2005 new
Up-regulation of the error-prone DNA polymerase {kappa} promotes pleiotropic genetic alterations and tumorigenesis. Clarisse Bavoux, Andréia Machado Leopoldino, Valérie Bergoglio, Jiyang O-Wang, Tomoo Ogi, Anne Bieth, Jean-Gabriel Judde, Sérgio Danilo Junho Pena, Marie-France Poupon, Thomas Helleday, Masatoshi Tagawa, Carlosrenato Machado, Jean-Sébastien Hoffmann, Christophe Cazaux Cancer research 2005 pols set
The pH-dependent mismatch formation by DNA polymerase eta. Shunji Izuta, Naomi Nishimoto Nucleic Acids Symp Ser (Oxf) 2005 new
The overexpression of specialized DNA polymerases in cancer. Mark R Albertella, Alan Lau, Mark J O'Connor DNA repair 2005 new
Assessment of the genotoxic potential of nitric oxide-induced guanine lesions by in vitro reactions with Escherichia coli DNA polymerase I. Toshiaki Nakano, Kenjiro Asagoshi, Hiroaki Terato, Toshinori Suzuki, Hiroshi Ide Mutagenesis 2005 pols set
Modulation of oxidative mutagenesis and carcinogenesis by polymorphic forms of human DNA repair enzymes. Takehiko Nohmi, Su-Ryang Kim, Masami Yamada Mutation research 2005 complete Brad Langhorst
Roles of replicative and specialized DNA polymerases in frameshift mutagenesis: mutability of Salmonella typhimurium strains lacking one or all of SOS-inducible DNA polymerases to 26 chemicals. Kiyoko Kokubo, Masami Yamada, Yusuke Kanke, Takehiko Nohmi DNA repair 2005 topics set
Mechanism for N-acetyl-2-aminofluorene-induced frameshift mutagenesis by Escherichia coli DNA polymerase I (Klenow fragment). JP Gill, Louis J Romano Biochemistry 2005 pols set
Optimal conditions and specific characteristics of Vent exo- DNA polymerase in ligation-mediated polymerase chain reaction protocols. François Vigneault, Régen Drouin Biochem Cell Biol 2005 pols set
4-Benzyl and 4-benzoyl-3-dimethylaminopyridin-2(1H)-ones: in vitro evaluation of new C-3-amino-substituted and C-5,6-alkyl-substituted analogues against clinically important HIV mutant strains. Abdellah Benjahad, Martine Croisy, Claude Monneret, Emile Bisagni, Dominique Mabire, Sophie Coupa, Alain Poncelet, Imre Csoka, Jérôme Guillemont, Christophe Meyer, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune, Daniel M Himmel, Kalyan Das, Edward Arnold, Chi Hung Nguyen, David S Grierson Journal of medicinal chemistry 2005 pols set
Mutagenesis induced by oxidized DNA precursors: roles of Y family DNA polymerases in Escherichia coli. Kazuya Satou, Masami Yamada, Takehiko Nohmi, Hideyoshi Harashima, Hiroyuki Kamiya Chemical research in toxicology 2005 topics set
Mismatch-induced conformational distortions in polymerase beta support an induced-fit mechanism for fidelity. Karunesh Arora, William A Beard, Samuel H Wilson, Tamar Schlick Biochemistry 2005 new
Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis. Alexandra Vaisman, Hong Ling, Roger Woodgate, Wei Wen Yang The EMBO journal 2005 topics set
The murine DNA glycosylase NEIL2 (mNEIL2) and human DNA polymerase beta bind microtubules in situ and in vitro. Kimberly A Conlon, Holly Miller, Thomas A Rosenquist, Dmitry O Zharkov, Miguel Berrios DNA repair 2005 complete Miguel Berrios*
Acylphloroglucinol derivatives from Mahurea palustris. Georges Massiot, Christophe Long, Bruno David, Marie-Jeanne Serrano, Florence Daubié, Frédéric Alby, Frédéric Ausseil, Martine Knibiehler, Christian Moretti, Jean-Sébastien Hoffmann, Christophe Cazaux, Catherine Lavaud Journal of natural products 2005 pols set
DNA polymerase clamp loaders and DNA recognition. Gregory D Bowman, Eric R Goedken, Steven L Kazmirski, Mike E O'Donnell, John Kuriyan FEBS letters 2005 new
RNAi Europe 2005. Ben Berkhout IDrugs 2005 new
Error-prone DNA polymerase IV is regulated by the heat shock chaperone GroE in Escherichia coli. Jill C Layton, Patricia L Foster J Bacteriol 2005 topics set
Immortalization of human small airway epithelial cells by ectopic expression of telomerase. Chang Q Piao, Li Liu, Yong L Zhao, Adayabalam S Balajee, Motoshi Suzuki, Tom K Hei Carcinogenesis 2005 new
Synthesis of universal unmethylated control DNA by nested whole genome amplification with phi29 DNA polymerase. Naoyuki Umetani, Michiel F G de Maat, Takuji Mori, Hiroya Takeuchi, Dave S B Hoon Biochem Biophys Res Commun 2005 pols set
Incorporation of reporter-labeled nucleotides by DNA polymerases. Jon P Anderson, Bernhard Angerer, Lawrence A Loeb BioTechniques 2005 partial results
Hinge residue Ile260 of DNA polymerase beta is important for enzyme activity and fidelity. Daniela Starcevic, Shibani Dalal, Joann B Sweasy Biochemistry 2005 new
A new in vivo termination function for DNA polymerase I of Escherichia coli K12. Alvin Markovitz Molecular microbiology 2005 pols set
Kinetics of nucleotide incorporation opposite DNA bulky guanine N2 adducts by processive bacteriophage T7 DNA polymerase (exonuclease-) and HIV-1 reverse transcriptase. Hong Zang, Thomas M Harris, F Peter Guengerich The Journal of biological chemistry 2005 pols set
Kinetics of nucleotide incorporation opposite polycyclic aromatic hydrocarbon-DNA adducts by processive bacteriophage T7 DNA polymerase. Hong Zang, Thomas M Harris, F Peter Guengerich Chemical research in toxicology 2005 pols set
Site specific synthesis and polymerase bypass of oligonucleotides containing a 6-hydroxy-3,5,6,7-tetrahydro-9H-imidazo[1,2-a]purin-9-one base, an intermediate in the formation of 1,N2-etheno-2'-deoxyguanosine. Angela K Goodenough, Ivan D Kozekov, Hong Zang, Jeong-Yun Choi, F Peter Guengerich, Thomas M Harris, Carmelo J Rizzo Chemical research in toxicology 2005 topics set
Molecular dynamics of a food carcinogen-DNA adduct in a replicative DNA polymerase suggest hindered nucleotide incorporation and extension. Ling Zhang, Robert Shapiro, Suse Broyde Chemical research in toxicology 2005 new
Accommodation of a 1S-(-)-benzo[c]phenanthrenyl-N6-dA adduct in the Y-family Dpo4 DNA polymerase active site: structural insights through molecular dynamics simulations. Liming Wang, Min Wu, S Frank Yan, Dinshaw J Patel, Nicholas E Geacintov, Suse Broyde Chemical research in toxicology 2005 topics set
Affinity capture of a mammalian DNA polymerase beta by inhibitors immobilized to resins used in solid-phase organic synthesis. Kouji Kuramochi, Tetsuya Haruyama, Ryo Takeuchi, Takashi Sunoki, Madoka Watanabe, Masahiko Oshige, Susumu Kobayashi, Kengo Sakaguchi, Fumio Sugawara Bioconjug Chem 2005 pols set
Transcription factor YB-1 mediates DNA polymerase alpha gene expression. Abdelaziz En-Nia, Emek Yilmaz, Uwe Klinge, David H Lovett, Ioannis Stefanidis, Peter R Mertens The Journal of biological chemistry 2005 new
Biochemical properties of Saccharomyces cerevisiae DNA polymerase IV. Katarzyna Bebenek, Miguel Garcia-Diaz, Steven R Patishall, Thomas A Kunkel The Journal of biological chemistry 2005 pols set
Mitochondrial DNA polymerase W748S mutation: a common cause of autosomal recessive ataxia with ancient European origin. Anna H Hakonen, Silja Heiskanen, Vesa Juvonen, Ilse Lappalainen, Petri T Luoma, Maria Rantamaki, Gert Van Goethem, Ann Lofgren, Peter Hackman, Anders Paetau, Seppo Kaakkola, Kari Majamaa, Teppo Varilo, Bjarne Udd, Helena Kaariainen, Laurence A Bindoff, Anu Suomalainen American journal of human genetics 2005 pols set
Complex formation of yeast Rev1 and Rev7 proteins: a novel role for the polymerase-associated domain. Narottam Acharya, Lajos Haracska, Robert E Johnson, Ildiko Unk, Satya Prakash, Louise Prakash Molecular and cellular biology 2005 new
High plasma HIV load in the CRF01-AE outbreak among injecting drug users in Finland. Pia S Kivelä, Anneke Krol, Mika O Salminen, Ronald B Geskus, Jukka I Suni, Veli-Jukka Anttila, Kirsi Liitsola, Veera Zetterberg, Frank Miedema, Ben Berkhout, Roel A Coutinho, Matti A Ristola Scand J Infect Dis 2005 new
Localisation of human Y-family DNA polymerase kappa: relationship to PCNA foci. Tomoo Ogi, Patricia L Kannouche, Alan R Lehmann J Cell Sci 2005 new
Functional defects due to spacer-region mutations of human mitochondrial DNA polymerase in a family with an ataxia-myopathy syndrome. Petri T Luoma, Ningguang Luo, Wolfgang N Löscher, Carol L Farr, Rita Horvath, Julia Wanschitz, Stefan Kiechl, Laurie S Kaguni, Anu Suomalainen Human molecular genetics 2005 pols set
The 3'-azido group is not the primary determinant of 3'-azido-3'-deoxythymidine (AZT) responsible for the excision phenotype of AZT-resistant HIV-1. Nicolas Sluis-Cremer, Dominique Arion, Urvi Parikh, Dianna Koontz, Raymond F Schinazi, John W Mellors, Michael A. Parniak The Journal of biological chemistry 2005 topics set
Low frequency of mtDNA point mutations in patients with PEO associated with POLG1 mutations. Gittan Kollberg, Monica Jansson, Asa Pérez-Bercoff, Atle Melberg, Christopher Lindberg, Elisabeth Holme, Ali-Reza Moslemi, Anders Oldfors European journal of human genetics : EJHG 2005 pols set
Systematic synthesis of galloyl-substituted procyanidin B1 and B2, and their ability of DPPH radical scavenging activity and inhibitory activity of DNA polymerases. Akiko Saito, Yoshiyuki Mizushina, Hiroshi Ikawa, Hiromi Yoshida, Yuki Doi, Akira Tanaka, Noriyuki Nakajima Bioorganic & medicinal chemistry 2005 new
Error-prone and inefficient replication across 8-hydroxyguanine (8-oxoguanine) in human and mouse ras gene fragments by DNA polymerase kappa. Paweł Jałoszyński, Eiji Ohashi, Haruo Ohmori, Susumu Nishimura Genes Cells 2005 new
Human DNA polymerase eta promotes DNA synthesis from strand invasion intermediates of homologous recombination. Michael J McIlwraith, Michael J Mcllwraith, Alexandra Vaisman, Yilun Liu, Ellen Fanning, Roger Woodgate, Stephen C West Molecular cell 2005 pols set
Further characterization of human DNA polymerase delta interacting protein 38. Bin Xie, Hao Li, Qi Wang, Suqing Xie, Amal A Rahmeh, Wei Dai, Marietta Y W T Lee The Journal of biological chemistry 2005 pols set
TMC125 displays a high genetic barrier to the development of resistance: evidence from in vitro selection experiments. Johan Vingerhoets, Hilde Azijn, Els Fransen, Inky De Baere, Liesbet Smeulders, Dirk Jochmans, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune Journal of virology 2005 topics set
Genetic interaction between DNA polymerase beta and DNA-PKcs in embryogenesis and neurogenesis. Naoko Niimi, Noriyuki Sugo, Yasuaki Aratani, Hideki Koyama Cell Death Differ 2005 new
Inhibitory effect of mispyric acid on mammalian DNA polymerases. Yoshiyuki Mizushina, Hirosato Takikawa, Yusuke Imamura, Mitsuru Sasaki, Kenji Mori, Hiromi Yoshida Bioscience, biotechnology, and biochemistry 2005 new
Structure-function studies of DNA polymerase lambda. Miguel Garcia-Diaz, Katarzyna Bebenek, Guanghua Gao, Lars C Pedersen, Robert E London, Thomas A Kunkel DNA repair 2005 new
DNA polymerase beta and flap endonuclease 1 enzymatic specificities sustain DNA synthesis for long patch base excision repair. Yuan Liu, William A Beard, David D Shock, Rajendra Prasad, Esther W Hou, Samuel H Wilson The Journal of biological chemistry 2005 new
In search of a novel anti-HIV drug: multidisciplinary coordination in the discovery of 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile (R278474, rilpivirine). Paul A J Janssen, Paul J Lewi, Edward Arnold, Frits F D Daeyaert, Marc R De Jonge, Jan Heeres, Luc Koymans, Maarten H Vinkers, Jérôme Guillemont, Elisabeth Pasquier, Michael Kukla, Don Ludovici, Koen Andries, Marie-Pierre P De Béthune, Rudi Pauwels, Kalyan Das, Arthur D Clark, Yulia Volovik Frenkel, Stephen H Hughes, Bart Medaer, Fons De Knaep, Hilde Bohets, Fred De Clerck, Ann Lampo, Peter Williams, Paul Stoffels J Med Chem 2005 new
Open clamp structure in the clamp-loading complex visualized by electron microscopic image analysis. Tomoko Miyata, Hirofumi Suzuki, Takuji Oyama, Kouta Mayanagi, Yoshizumi Ishino, Kosuke Morikawa Proceedings of the National Academy of Sciences of the United States of America 2005 new
Rev1 employs a novel mechanism of DNA synthesis using a protein template. Deepak T Nair, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Science (New York, N.Y.) 2005 new
Involvement of the "linker" region between the exonuclease and polymerization domains of phi29 DNA polymerase in DNA and TP binding. Verónica Truniger, Ana Bonnin, José María Lázaro, Miguel de Vega, Margarita Salas Gene 2005 partial results
The herpes simplex virus type 1 DNA polymerase processivity factor, UL42, does not alter the catalytic activity of the UL9 origin-binding protein but facilitates its loading onto DNA. Kelly S Trego, Yali Zhu, Deborah S Parris Nucleic acids research 2005 complete Deborah S Parris*
DNA polymerase kappa is specifically required for recovery from the benzo[a]pyrene-dihydrodiol epoxide (BPDE)-induced S-phase checkpoint. Xiaohui Bi, Damien M Slater, Haruo Ohmori, Cyrus Vaziri The Journal of biological chemistry 2005 new
Structure and mechanism of DNA polymerases. Paul J Rothwell, Gabriel Waksman Adv Protein Chem 2005 topics set
Oxidative stress-induced retinal damage up-regulates DNA polymerase gamma and 8-oxoguanine-DNA-glycosylase in photoreceptor synaptic mitochondria. M Soledad Cortina, William C Gordon, Walter J Lukiw, Nicolas G Bazan Exp Eye Res 2005 new
Transcriptional profiling of human herpesvirus type B (HHV-6B) in an adult T cell leukemia cell line as in vitro model for persistent infection. Junko H Ohyashiki, Tomoiku Takaku, Tomoko Ojima, Kenji Abe, Kohtaro Yamamoto, Yongqing Zhang, Kazuma Ohyashiki Biochemical and biophysical research communications 2005 new
Structural analysis of epolactaene derivatives as DNA polymerase inhibitors and anti-inflammatory compounds. Yoshiyuki Mizushina, Kouji Kuramochi, Hiroshi Ikawa, Isoko Kuriyama, Noriko Shimazaki, Masaharu Takemura, Masahiko Oshige, Hiromi Yoshida, Osamu Koiwai, Fumio Sugawara, Susumu Kobayashi, Kengo Sakaguchi Int J Mol Med 2005 new
Chromosomal translocations in yeast induced by low levels of DNA polymerase a model for chromosome fragile sites. Francene J Lemoine, Natasha P Degtyareva, Kirill Lobachev, Thomas D Petes Cell 2005 new
Mechanism of efficient and accurate nucleotide incorporation opposite 7,8-dihydro-8-oxoguanine by Saccharomyces cerevisiae DNA polymerase eta. Karissa D Carlson, M Todd Washington Molecular and cellular biology 2005 complete M Todd Washington*
Construction of a minimal HIV-1 variant that selectively replicates in leukemic derived T-cell lines: towards a new virotherapy approach. Rienk E Jeeninga, Barbara Jan, Birgit van der Linden, Henk van den Berg, Ben Berkhout Cancer research 2005 new
Saccharomyces cerevisiae DNA polymerase delta: high fidelity for base substitutions but lower fidelity for single- and multi-base deletions. John M Fortune, Youri I Pavlov, Carrie M Welch, Erik Johansson, Peter M J Burgers, Thomas A Kunkel The Journal of biological chemistry 2005 pols set
Is the CAG repeat of mitochondrial DNA polymerase gamma (POLG) associated with male infertility? A multi-centre French study. I E Aknin-Seifer, R L Touraine, H Lejeune, C Jimenez, J Chouteau, J P Siffroi, K McElreavey, T Bienvenu, C Patrat, R Levy Human reproduction (Oxford, England) 2005 new
Photoregulation of DNA polymerase I (Klenow) with caged fluorescent oligodeoxynucleotides. XinJing Tang, Julia L Richards, Adam E Peritz, Ivan J Dmochowski Bioorganic & medicinal chemistry letters 2005 complete Ivan J Dmochowski*
Progressive external ophthalmoplegia: a new family with tremor and peripheral neuropathy. Fuki M Hisama, Michelangelo Mancuso, Massimiliano Filosto, Salvatore DiMauro American journal of medical genetics. Part A 2005 pols set
Concentration and pH dependent aggregation of hydrophobic drug molecules and relevance to oral bioavailability. Yulia Volovik Frenkel, Arthur D Clark, Kalyan Das, Yuh-Hwa Wang, Paul J Lewi, Paul A J Janssen, Edward Arnold J Med Chem 2005 new
Autosomal recessive mitochondrial ataxic syndrome due to mitochondrial polymerase gamma mutations. Synnøve Winterthun, Gianfrancesco Ferrari, L He, Robert W Taylor, Massimo Zeviani, Douglass M Turnbull, Bernt A Engelsen, G Moen, Laurence A Bindoff Neurology 2005 pols set
Alzheimer pathology associated with POLG1 mutation, multiple mtDNA deletions, and APOE4/4: premature ageing or just coincidence? Atle Melberg, Inger Nennesmo, Ali-Reza Moslemi, Gittan Kollberg, Petri Luoma, Anu Suomalainen, Elisabeth Holme, Anders Oldfors Acta neuropathologica 2005 pols set
DNA adduct bypass polymerization by Sulfolobus solfataricus DNA polymerase Dpo4: analysis and crystal structures of multiple base pair substitution and frameshift products with the adduct 1,N2-ethenoguanine. Hong Zang, Angela K Goodenough, Jeong-Yun Choi, Adriana Irimia, Lioudmila V Loukachevitch, Ivan D Kozekov, Karen C Angel, Carmelo J Rizzo, Martin Egli, F Peter Guengerich The Journal of biological chemistry 2005 topics set
The bacteriophage P1 hot gene product can substitute for the Escherichia coli DNA polymerase III {theta} subunit. Anna K Chikova, Roel M Schaaper J Bacteriol 2005 pols set
Mono-allelic POLG expression resulting from nonsense-mediated decay and alternative splicing in a patient with Alpers syndrome. Sherine S L Chan, Matthew J Longley, Robert K Naviaux, William C Copeland DNA repair 2005 pols set
A role for polymerase eta in the cellular tolerance to cisplatin-induced damage. Mark R Albertella, Catherine M Green, Alan R Lehmann, Mark J O'Connor Cancer research 2005 new
Changing patterns in the selection of viral mutations among patients receiving nucleoside and nucleotide drug combinations directed against human immunodeficiency virus type 1 reverse transcriptase. Mark A. Wainberg, Bluma G Brenner, Dan Turner Antimicrobial agents and chemotherapy 2005 new
The role of DNA polymerase eta in UV mutational spectra. Jun-Hyuk Choi, Gerd P Pfeifer DNA repair 2005 new
Ubiquitinated proliferating cell nuclear antigen activates translesion DNA polymerases eta and REV1. Parie Garg, Peter M J Burgers Proceedings of the National Academy of Sciences of the United States of America 2005 new
Probing the active site tightness of DNA polymerase in subangstrom increments. Tae Woo Kim, James C Delaney, John M Essigmann, Eric T Kool Proceedings of the National Academy of Sciences of the United States of America 2005 new
The L74V mutation in human immunodeficiency virus type 1 reverse transcriptase counteracts enhanced excision of zidovudine monophosphate associated with thymidine analog resistance mutations. Luis R Miranda, Matthias Götte, Fei Liang, Daniel R Kuritzkes Antimicrob Agents Chemother 2005 topics set
Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN--gp120 interaction. Fedde Groot, Teunis B H Geijtenbeek, Rogier W Sanders, Christopher E Baldwin, Marta Sanchez-Hernandez, René Floris, Yvette van Kooyk, Esther C de Jong, Ben Berkhout J Virol 2005 new
Increased multinucleoside drug resistance and decreased replicative capacity of a human immunodeficiency virus type 1 variant with an 8-amino-Acid insert in the reverse transcriptase. Lia van der Hoek, Nicole Back, Maarten F Jebbink, Anthony de Ronde, Margreet Bakker, Suzanne Jurriaans, Peter Reiss, Neil Parkin, Ben Berkhout J Virol 2005 topics set
Aggressive HIV-1? Ben Berkhout, Anthony de Ronde, Lia van der Hoek Retrovirology 2005 new
Pyridine N-oxide derivatives: unusual anti-HIV compounds with multiple mechanisms of antiviral action. Jan Balzarini, Miguel Stevens, Erik De Clercq, Dominique Schols, Christophe Pannecouque The Journal of antimicrobial chemotherapy 2005 pols set
Marked depletion of glycosylation sites in HIV-1 gp120 under selection pressure by the mannose-specific plant lectins of Hippeastrum hybrid and Galanthus nivalis. Jan Balzarini, Kristel Van Laethem, Sigrid Hatse, Matheus Froeyen, Els Van Damme, Anders Bolmstedt, Willy Peumans, Erik De Clercq, Dominique Schols Molecular pharmacology 2005 pols set
High-level overproduction of His-tagged Tth DNA polymerase in Thermus thermophilus. Renata Moreno, Amparo Haro, Angel Castellanos, José Berenguer Appl Environ Microbiol 2005 pols set
Causal pathways of the effects of age and the CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on AIDS development. Ronald B Geskus, Laurence Meyer, Jean-Baptiste Hubert, Hanneke Schuitemaker, Ben Berkhout, Christine Rouzioux, Ioannis D Theodorou, Jean-François Delfraissy, Maria Prins, Roel A Coutinho J Acquir Immune Defic Syndr 2005 new
Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry. Heike Hofmann, Krzysztof Pyrc, Lia van der Hoek, Martina Geier, Ben Berkhout, Stefan Pöhlmann Proceedings of the National Academy of Sciences of the United States of America 2005 new
Trf4 and Trf5 proteins of Saccharomyces cerevisiae exhibit poly(A) RNA polymerase activity but no DNA polymerase activity. Lajos Haracska, Robert E Johnson, Louise Prakash, Satya Prakash Molecular and cellular biology 2005 topics set
[Expressions of telomerase reverse transcriptase and vascular endothelial growth factor and their correlation in prostate cancer]. Xincang Li, Na Wang, Yongqing Zhang, Shun-xin Zhang, Qian Lin, Jie Tang Zhonghua nan ke xue = National journal of andrology 2005 new
Antiadenovirus activities of several classes of nucleoside and nucleotide analogues. Lieve Naesens, L Lenaerts, Graciella Andrei, Robert Snoeck, D Van Beers, Antonin Holy, Jan Balzarini, Erik De Clercq Antimicrobial agents and chemotherapy 2005 new
Effects of DNA polymerase inhibitory and antitumor activities of lipase-hydrolyzed glycolipid fractions from spinach. Naoki Maeda, Takahiko Hada, Chikako Murakami-Nakai, Isoko Kuriyama, Hideki Ichikawa, Yoshinobu Fukumori, Junichi Hiratsuka, Hiromi Yoshida, Kengo Sakaguchi, Yoshiyuki Mizushina J Nutr Biochem 2005 new
Sensitivity to phosphonoacetic acid: a new phenotype to probe DNA polymerase delta in Saccharomyces cerevisiae. Lin Li, Kelly M Murphy, Uliana Kanevets, Linda J Reha-Krantz Genetics 2005 complete Linda J Reha-Krantz*
Polymerization past the N2-isopropylguanine and the N6-isopropyladenine DNA lesions with the translesion synthesis DNA polymerases eta and iota and the replicative DNA polymerase alpha. Fred W Perrino, Scott Harvey, Patrick Blans, Stacy L Gelhaus, William R Lacourse, James C Fishbein Chemical research in toxicology 2005 new
DNA polymerase I acts in translesion synthesis mediated by the Y-polymerases in Bacillus subtilis. Stéphane Duigou, S Dusko Ehrlich, Philippe Noirot, Marie-Françoise Noirot-Gros Molecular microbiology 2005 new
The amino acid Asn136 in HIV-1 reverse transcriptase (RT) maintains efficient association of both RT subunits and enables the rational design of novel RT inhibitors. Jan Balzarini, Joeri Auwerx, Fátima Rodríguez-Barrios, Allel Chedad, Viktor Farkas, F Ceccherini-Silberstein, Carlos García-Aparicio, Sonsoles Velázquez, Erik De Clercq, CF Perno, María-José Camarasa, Federico Gago Molecular pharmacology 2005 pols set
Design and synthesis of a 3'-O-allyl photocleavable fluorescent nucleotide as a reversible terminator for DNA sequencing by synthesis. Hameer Ruparel, Lanrong Bi, Zengmin Li, Xiaopeng Bai, Dae Hyun Kim, Nicholas J Turro, Jingyue Ju Proceedings of the National Academy of Sciences of the United States of America 2005 new
Antiviral drug discovery and development: where chemistry meets with biomedicine. Erik De Clercq Antiviral research 2005 new
Structural insight into the DNA polymerase beta deoxyribose phosphate lyase mechanism. Rajendra Prasad, Vinod K Batra, Xiao-Ping Yang, Joseph M Krahn, Lars C Pedersen, William A Beard, Samuel H Wilson DNA repair 2005 topics set
The human checkpoint sensor and alternative DNA clamp Rad9-Rad1-Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery. Ekaterina Smirnova, Magali Toueille, Enni Markkanen, Ulrich Hübscher The Biochemical journal 2005 new
The N137 and P140 amino acids in the p51 and the P95 amino acid in the p66 subunit of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase are instrumental to maintain catalytic activity and to design new classes of anti-HIV-1 drugs. Joeri Auwerx, Joke Van Nieuwenhove, Fátima Rodríguez-Barrios, Sonia de Castro, Sonsoles Velázquez, F Ceccherini-Silberstein, Erik De Clercq, María-José Camarasa, CF Perno, Federico Gago, Jan Balzarini FEBS letters 2005 pols set
Synthesis and structural analysis of oxadiazole carboxamide deoxyribonucleoside analogs. Olga Adelfinskaya, Weidong Wu, V Jo Davisson, V J Davisson, Donald E Bergstrom Nucleosides, nucleotides & nucleic acids 2005 topics set
DNA polymerase beta promotes recruitment of DNA ligase III alpha-XRCC1 to sites of base excision repair. Jason L Parsons, Irina I Dianova, Sarah L Allinson, Grigory L Dianov Biochemistry 2005 new
Nonnucleoside HIV-1 reverse-transcriptase inhibitors, part 5. Synthesis and anti-HIV-1 activity of novel 6-naphthylthio HEPT analogues. Guang-Fu Sun, Xu-Xiang Chen, Fen-Er Chen, Yue-Ping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Chemical & pharmaceutical bulletin 2005 pols set
Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint. Tony S Byun, Marcin Pacek, Muh-ching Yee, Johannes C Walter, Karlene A Cimprich Genes Dev 2005 new
The multiple biological roles of the 3'-->5' exonuclease of Saccharomyces cerevisiae DNA polymerase delta require switching between the polymerase and exonuclease domains. Yong Hwan Jin, Parie Garg, Carrie M W Stith, Hanan Al-Refai, Joan F Sterling, Laura J W Murray, Thomas A Kunkel, Michael A Resnick, Peter M J Burgers, Dmitry A Gordenin Molecular and cellular biology 2005 partial results
A HIV-1 minimal gag protein is superior to nucleocapsid at in vitro annealing and exhibits multimerization-induced inhibition of reverse transcription. Ariel Roldan, Otis U Warren, Rodney S Russell, Chen Liang, Mark A. Wainberg The Journal of biological chemistry 2005 pols set
Human base excision repair enzymes apurinic/apyrimidinic endonuclease1 (APE1), DNA polymerase beta and poly(ADP-ribose) polymerase 1: interplay between strand-displacement DNA synthesis and proofreading exonuclease activity. Maria V Sukhanova, Svetlana N Khodyreva, Natalia A Lebedeva, Rajendra Prasad, Samuel H Wilson, Olga I Lavrik Nucleic acids research 2005 new
How the cell deals with DNA nicks. Parie Garg, Peter M J Burgers Cell Cycle 2005 new
Hierarchical database screenings for HIV-1 reverse transcriptase using a pharmacophore model, rigid docking, solvation docking, and MM-PB/SA. Junmei Wang, Xinshan Kang, Irwin D Kuntz, Peter A Kollman Journal of medicinal chemistry 2005 pols set
Human telomerase reverse transcriptase immortalizes bovine lens epithelial cells and suppresses differentiation through regulation of the ERK signaling pathway. Juan Wang, Hao Feng, Xiao-Qin Huang, Hua Xiang, Ying-Wei Mao, Jin-Ping Liu, Qin Yan, Wen-Bin Liu, Yan Liu, Mi Deng, Lili Gong, Shuming Sun, Chen Luo, Shao-Jun Liu, Xuan-Jie Zhang, Yun Liu, David Wan-Cheng Li The Journal of biological chemistry 2005 new
Synthesis of 5-(1-propynyl)-2'-deoxyuridine 5'-(alpha-P-borano)triphosphate and kinetic characterization as a substrate for mmlv reverse transcriptase. Joy Xin Wang, Barbara Ramsay Shaw Nucleosides, nucleotides & nucleic acids 2005 new
Crystal structures for HIV-1 reverse transcriptase in complexes with three pyridinone derivatives: a new class of non-nucleoside inhibitors effective against a broad range of drug-resistant strains. Daniel M Himmel, Kalyan Das, Arthur D Clark, Stephen H Hughes, Abdellah Benjahad, Said Oumouch, Jérôme Guillemont, Sophie Coupa, Alain Poncelet, Imre Csoka, Christophe Meyer, Koen Andries, Chi Hung Nguyen, David S Grierson, Edward Arnold J Med Chem 2005 partial results
Pre-steady-state kinetic characterization of the DinB homologue DNA polymerase of Sulfolobus solfataricus. Janina Cramer, Tobias Restle The Journal of biological chemistry 2005 pols set
Overproduction of DNA polymerase eta does not raise the spontaneous mutation rate in diploid human fibroblasts. Nicole M King, Nana Nikolaishvili-Feinberg, Miriam F Bryant, Douglas D Luche, Timothy P Heffernan, Dennis A Simpson, Fumio Hanaoka, William K Kaufmann, Marila Cordeiro-Stone DNA repair 2005 pols set
Mutations in the spacer region of Drosophila mitochondrial DNA polymerase affect DNA binding, processivity, and the balance between Pol and Exo function. Ningguang Luo, Laurie S Kaguni The Journal of biological chemistry 2005 new
Phenotypic characterisation of cytomegalovirus DNA polymerase: a method to study cytomegalovirus isolates resistant to foscarnet. Alexandra Ducancelle, Jérôme Gravisse, Sophie Alain, Anne-Marie Fillet, Françoise Petit, Marie-José Sanson Le Pors, Marie-Christine Mazeron J Virol Methods 2005 new
Nuclear magnetic resonance solution structure of the Escherichia coli DNA polymerase III theta subunit. Geoffrey A Mueller, Thomas W Kirby, Eugene F DeRose, Dawei Li, Roel M Schaaper, Robert E London J Bacteriol 2005 topics set
The HIV-1 leader RNA conformational switch regulates RNA dimerization but does not regulate mRNA translation. Truus E M Abbink, Marcel Ooms, P C Joost Haasnoot, Ben Berkhout Biochemistry 2005 new
A thymine isostere in the templating position disrupts assembly of the closed DNA polymerase beta ternary complex. Thomas W Kirby, Eugene F DeRose, William A Beard, Samuel H Wilson, Robert E London Biochemistry 2005 new
Application of Phi29 DNA polymerase mediated whole genome amplification on single spores of arbuscular mycorrhizal (AM) fungi. Vijay Gadkar, Matthias C Rillig FEMS Microbiol Lett 2005 pols set
Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function. Satya Prakash, Robert E Johnson, Louise Prakash Annu Rev Biochem 2005 topics set
Substitutions in the reverse transcriptase and protease genes of HIV-1 subtype B in untreated individuals and patients treated with antiretroviral drugs. Dan Turner, Bluma G Brenner, Daniela Mosis, Chen Liang, Mark A. Wainberg MedGenMed : Medscape general medicine 2005 pols set
hTERT extends proliferative lifespan and prevents oxidative stress-induced apoptosis in human lens epithelial cells. Xiao-Qin Huang, Juan Wang, Jin-Ping Liu, Hao Feng, Wen-Bin Liu, Qin Yan, Yan Liu, Shu-Ming Sun, Mi Deng, Lili Gong, Yun Liu, David Wan-Cheng Li Investigative ophthalmology & visual science 2005 new
Prostate-cancer-associated I260M variant of DNA polymerase beta is a sequence-specific mutator. Shibani Dalal, Suzanne E Hile, Kristin A Eckert, Ka-Wai Sun, Daniela Starcevic, Joann B Sweasy Biochemistry 2005 new
A novel heme-containing protein with anti-HIV-1 activity from skin secretions of Bufo andrewsi. Yaofeng Zhao, Yang Jin, Jing-Houng Wang, Rui-Rui Wang, Liu-Meng Yang, Wen-Hui Lee, Yong-Tang Zheng, Yongqing Zhang Toxicon : official journal of the International Society on Toxinology 2005 pols set
[Genotypic antiretroviral resistance testing and phylogenetic analysis of protease and reverse transcriptase in antiretroviral drug-naïve AIDS patients in Henan province]. Kun Yang, Jing-Yun Li, Zuo-Yi Bao, Han-Ping Li, Lin Li, Dao-Min Zhuang, Zhengqiang Wang, Hong Li Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 2005 new
[Study on adherence and interrelated factors of acquired immunedeficiency syndrome patients receiving antiretroviral treatment]. Hong Li, Zhengqiang Wang, Wei-guo Cui, Yan Liang, Tian-yi Xin, Jinming Li Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 2005 pols set
Mutant forms of the Escherichia colibeta sliding clamp that distinguish between its roles in replication and DNA polymerase V-dependent translesion DNA synthesis. Mark D Sutton, Jill M Duzen, Robert W Maul Molecular microbiology 2005 new
Attempt to reduce cytotoxicity by synthesizing the L-enantiomer of 4'-C-ethynyl-2'-deoxypurine nucleosides as antiviral agents against HIV and HBV. Kenji Kitano, Satoru Kohgo, Kohei Yamada, Shinji Sakata, Noriyuki Ashida, Hiroyuki Hayakawa, Daisuke Nameki, Eiichi N Kodama, Masao Matsuoka, Hiroyuki Mitsuya, Hiroshi Ohrui Antivir Chem Chemother 2004 new
Lesion bypass by human DNA polymerase mu reveals a template-dependent, sequence-independent nucleotidyl transferase activity. Shay Covo, Luis Blanco, Zvi Livneh The Journal of biological chemistry 2004 pols set
Sequence analysis of familial PEO shows additional mutations associated with the 752C-->T and 3527C-->T changes in the POLG1 gene. Eleonora Lamantea, Massimo Zeviani Annals of neurology 2004 pols set
Characterization of the 3' exonuclease subunit DP1 of Methanococcus jannaschii replicative DNA polymerase D. Maarit Jokela, Anitta Eskelinen, Helmut Pospiech, Juha Rouvinen, Juhani E Syväoja Nucleic acids research 2004 new
Analysis of non-template-directed nucleotide addition and template switching by DNA polymerase. Patty B García, Nicole L Robledo, Angel L Islas Biochemistry 2004 new
Molecular insights into NRTI inhibition and mitochondrial toxicity revealed from a structural model of the human mitochondrial DNA polymerase. Rachelle J Bienstock, Willliam C Copeland Mitochondrion 2004 pols set
Effects of the Delta67 complex of mutations in human immunodeficiency virus type 1 reverse transcriptase on nucleoside analog excision. Paul L Boyer, Tomozumi Imamichi, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes J Virol 2004 topics set
A structural solution for the DNA polymerase lambda-dependent repair of DNA gaps with minimal homology. Miguel Garcia-Diaz, Katarzyna Bebenek, Joseph M Krahn, Luis Blanco, Thomas A Kunkel, Lars C Pedersen Molecular cell 2004 topics set
Insights into DNA replication: the crystal structure of DNA polymerase B1 from the archaeon Sulfolobus solfataricus. Carmelinda Savino, Luca Federici, Kenneth A Johnson, Beatrice Vallone, Vassilios Nastopoulos, Mosè Rossi, Francesca M Pisani, Demetrius Tsernoglou Structure (London, England : 1993) 2004 complete Carmelinda Savino*
Altered DNA polymerase iota expression in breast cancer cells leads to a reduction in DNA replication fidelity and a higher rate of mutagenesis. Jin Yang, Zhiwen Chen, Yang Liu, Robert J Hickey, Linda H Malkas Cancer research 2004 new
The spacious active site of a Y-family DNA polymerase facilitates promiscuous nucleotide incorporation opposite a bulky carcinogen-DNA adduct: elucidating the structure-function relationship through experimental and computational approaches. Rebecca A Perlow-Poehnelt, Ilya Likhterov, David A Scicchitano, Nicholas E Geacintov, Suse Broyde The Journal of biological chemistry 2004 topics set
Detection of micrometastasis of gastric carcinoma in peripheral blood circulation. Xi-Mei Chen, Guo-Yu Chen, Zhi-Rong Wang, Feng-Shang Zhu, Xiao-Lei Wang, Xia Zhang World journal of gastroenterology : WJG 2004 new
Alternative splicing of human telomerase reverse transcriptase may not be involved in telomerase regulation during all-trans-retinoic acid-induced HL-60 cell differentiation. Wei-Jun Liu, Yong-Wei Zhang, Zhi-Xiang Zhang, Jian Ding Journal of pharmacological sciences 2004 new
Highly organized but pliant active site of DNA polymerase beta: compensatory mechanisms in mutant enzymes revealed by dynamics simulations and energy analyses. Linjing Yang, William A Beard, Samuel H Wilson, Suse Broyde, Tamar Schlick Biophys J 2004 new
The human DNA polymerase lambda interacts with PCNA through a domain important for DNA primer binding and the interaction is inhibited by p21/WAF1/CIP1. Giovanni Maga, Giuseppina Blanca, Igor V Shevelev, Isabelle Frouin, Kristijan Ramadan, Silvio Spadari, Giuseppe Villani, Ulrich Hübscher FASEB J 2004 pols set
Investigating the role of the little finger domain of Y-family DNA polymerases in low fidelity synthesis and translesion replication. François Boudsocq, Robert J Kokoska, Brian S Plosky, Alexandra Vaisman, Hong Ling, Thomas A Kunkel, Wei Wen Yang, Roger Woodgate The Journal of biological chemistry 2004 topics set
Fluorescence measurements on the E.coli DNA polymerase clamp loader: implications for conformational changes during ATP and clamp binding. Eric R Goedken, Marcia Levitus, Aaron Johnson, Carlos Bustamante, Mike E O'Donnell, John Kuriyan Journal of molecular biology 2004 new
Pol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation. Simona Grossi, Andrea Puglisi, Petr V Dmitriev, Massimo Lopes, David Shore Genes Dev 2004 new
DNA polymerase gamma, the mitochondrial replicase. Laurie S Kaguni Annu Rev Biochem 2004 new
Determination of DNA guanine sites forming photo-adducts with Ru(II)-labeled oligonucleotides; DNA polymerase inhibition by the resulting photo-crosslinking. Olivier Lentzen, Eric Defrancq, Jean-François Constant, Stephan Schumm, David García-Fresnadillo, Cécile Moucheron, Pascal Dumy, Andrée Kirsch-De Mesmaeker J Biol Inorg Chem 2004 new
To slip or skip, visualizing frameshift mutation dynamics for error-prone DNA polymerases. Brigette Tippin, Sawami Kobayashi, Jeffrey G Bertram, Myron F Goodman The Journal of biological chemistry 2004 new
The cytomegalovirus DNA polymerase subunit UL44 forms a C clamp-shaped dimer. Brent A Appleton, Arianna Loregian, David J Filman, Donald M Coen, James M Hogle Molecular cell 2004 pols set
Extreme free energy of stabilization of Taq DNA polymerase. Allyn J Schoeffler, Allison M Joubert, Fenggang Peng, Farheen Khan, Chin-Chi Liu, Vince J LiCata Proteins 2004 pols set
In vitro mutation artifacts after formalin fixation and error prone translesion synthesis during PCR. Nancy Quach, Myron F Goodman, Darryl Shibata BMC clinical pathology 2004 pols set
Implantation of BM cells transfected with phVEGF165 enhances functional improvement of the infarcted heart. H-X Xu, G-S Li, H Jiang, Juan Wang, J-J Lü, W Jiang, H-Y Qian, X-J Jiang, X-Y Li, J-J Li, W-H Liu Cytotherapy 2004 new
A single amino acid change (E85K) in human PCNA that leads, relative to wild type, to enhanced DNA synthesis by DNA polymerase delta past nucleotide base lesions (TLS) as well as on unmodified templates. Paul A Fisher, Demetrius L Moutsiakis, Maeve McConnell, Holly Miller, Dmitry Ju Mozzherin Biochemistry 2004 new
Translesion synthesis past estrogen-derived DNA adducts by human DNA polymerases eta and kappa. Naomi Suzuki, Shinji Itoh, Kinning Poon, Chikahide Masutani, Fumio Hanaoka, Haruo Ohmori, Itsuo Yoshizawa, Shinya Shibutani Biochemistry 2004 pols set
Rationale for maintenance of the M184v resistance mutation in human immunodeficiency virus type 1 reverse transcriptase in treatment experienced patients. Dan Turner, Bluma G Brenner, Jean-Pierre Routy, Marco Petrella, Mark A. Wainberg The new microbiologica 2004 pols set
Sequential switching of DNA polymerase and thymidine kinase-mediated HSV-1 drug resistance in an immunocompromised child. Růzena Stránská, Anton M van Loon, Robbert G M Bredius, Merjo Polman, Elske Nienhuis, Matthias F C Beersma, Arjan C Lankester, Rob Schuurman Antivir Ther 2004 new
Marine sesquiterpenoids that inhibit the lyase activity of DNA polymerase beta. Shugeng Cao, Zhijie Gao, Shannon J Thomas, Sidney M Hecht, John S Lazo, David G I Kingston J Nat Prod 2004 new
Absence of DNA polymerase eta reveals targeting of C mutations on the nontranscribed strand in immunoglobulin switch regions. Xianmin Zeng, George A Negrete, Cynthia Kasmer, William W Yang, Patricia J Gearhart J Exp Med 2004 new
L-Homoserylaminoethanol, a novel dipeptide alcohol inhibitor of eukaryotic DNA polymerase from a plant cultured cells, Nicotina tabacum L. Isoko Kuriyama, Naoki Asano, Ikunoshin Kato, Masahiko Oshige, Akio Sugino, Yasuhiro Kadota, Kazuyuki Kuchitsu, Hiromi Yoshida, Kengo Sakaguchi, Yoshiyuki Mizushina Bioorg Med Chem 2004 new
Preferential cis-syn thymine dimer bypass by DNA polymerase eta occurs with biased fidelity. Scott D McCulloch, Robert J Kokoska, Chikahide Masutani, Shigenori Iwai, Fumio Hanaoka, Thomas A Kunkel Nature 2004 pols set
Genetics of lagging strand DNA synthesis and maturation in fission yeast: suppression analysis links the Dna2-Cdc24 complex to DNA polymerase delta. Hiroyuki Tanaka, Gi-Hyuck Ryu, Yeon-Soo Seo, Stuart A MacNeill Nucleic acids research 2004 new
Cleavage of double-stranded DNA by the intrinsic 3'-5' exonuclease activity of DNA polymerase B1 from the hyperthermophilic archaeon Sulfolobus solfataricus at high temperature. Huiqiang Lou, Zhenhong Duan, Tong Sun, Li Huang FEMS Microbiol Lett 2004 new
Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase. Gerald W Hsu, James R Kiefer, Dominique Y Burnouf, Olivier J Becherel, Robert P P Fuchs, Lorena S Beese The Journal of biological chemistry 2004 topics set
Structure-activity relationships of epolactaene analogs as DNA polymerases inhibitors. Kouji Kuramochi, Yoshiyuki Mizushina, Seigo Nagata, Fumio Sugawara, Kengo Sakaguchi, Susumu Kobayashi Bioorganic & medicinal chemistry 2004 new
DNA polymerase beta interacts with TRF2 and induces telomere dysfunction in a murine mammary cell line. Poppy Fotiadou, Octavian Henegariu, Joann B Sweasy Cancer research 2004 new
In vitro selection of drug-resistant varicella-zoster virus (VZV) mutants (OKA strain): differences between acyclovir and penciclovir? Graciella Andrei, Erik De Clercq, Robert Snoeck Antiviral research 2004 topics set
Role of DNA polymerase eta in the bypass of abasic sites in yeast cells. Bo Zhao, Zhongwen Xie, Huiyun Shen, Zhengqiang Wang Nucleic acids research 2004 topics set
Experimental and structural evidence that herpes 1 kinase and cellular DNA polymerase(s) discriminate on the basis of sugar pucker. Victor E Marquez, Tsipi Ben-Kasus, Joseph J Barchi, Karen M Green, Marc C Nicklaus, Riad Agbaria Journal of the American Chemical Society 2004 new
Precise structural elucidation of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha. Shinji Kamisuki, Shunya Takahashi, Yoshiyuki Mizushina, Kengo Sakaguchi, Tadashi Nakata, Fumio Sugawara Bioorg Med Chem 2004 pols set
Impact of the translocational equilibrium of HIV-1 reverse transcriptase on the efficiency of mismatch extensions and the excision of mispaired nucleotides. Bruno Marchand, Matthias Götte Int J Biochem Cell Biol 2004 topics set
A 21-amino acid peptide from the cysteine cluster II of the family D DNA polymerase from Pyrococcus horikoshii stimulates its nuclease activity which is Mre11-like and prefers manganese ion as the cofactor. Yulong Shen, Xiao-Feng Tang, Hideshi Yokoyama, Eriko Matsui, Ikuo Matsui Nucleic acids research 2004 pols set
Mechanism of loading the Escherichia coli DNA polymerase III sliding clamp: II. Uncoupling the beta and DNA binding activities of the gamma complex. Anita K Snyder, Christopher R Williams, Aaron Johnson, Mike E O'Donnell, Linda B Bloom The Journal of biological chemistry 2004 pols set
Enzymatic switching for efficient and accurate translesion DNA replication. Scott D McCulloch, Robert J Kokoska, Olga Chilkova, Carrie M Welch, Erik Johansson, Peter M J Burgers, Thomas A Kunkel Nucleic acids research 2004 new
A novel DNA topoisomerase inhibitor: dehydroebriconic acid, one of the lanostane-type triterpene acids from Poria cocos. Yoshiyuki Mizushina, Toshihiro Akihisa, Motohiko Ukiya, Chikako Murakami, Isoko Kuriyama, Xianai Xu, Hiromi Yoshida, Kengo Sakaguchi Cancer science 2004 pols set
Dpo4 is hindered in extending a G.T mismatch by a reverse wobble. José Trincao, Robert E Johnson, William T Wolfle, Carlos R Escalante, Satya Prakash, Louise Prakash, Aneel K Aggarwal Nature structural & molecular biology 2004 topics set
A capillary electrophoretic assay for ribonuclease H activity. King C Chan, Scott R Budihas, Stuart F J Le Grice, Michael A. Parniak, Robert J Crouch, Sergei A Gaidamakov, Haleem J Isaaq, Antony Wamiru, James B McMahon, John A Beutler Analytical biochemistry 2004 pols set
Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 2. George A Freeman, C Webster Andrews Iii, Andrew L Hopkins, Gina S Lowell, Lee T Schaller, Jill R Cowan, Stephen S Gonzales, George W Koszalka, Richard J Hazen, Lawrence R Boone, Rob G Ferris, Katrina L Creech, Grace B Roberts, Steven A Short, Kurt L Weaver, David J Reynolds, John Milton, Jingshan Ren, David I Stuart, David K Stammers, Joseph H Chan J Med Chem 2004 partial results
Molecular design of cholesterols as inhibitors of DNA polymerase alpha. Masahiko Oshige, Kouji Kuramochi, Keisuke Ohta, Akitsu Ogawa, Hiroki Kuriyama, Fumio Sugawara, Susumu Kobayashi, Kengo Sakaguchi J Med Chem 2004 new
Dynamic characterization of a DNA repair enzyme: NMR studies of [methyl-13C]methionine-labeled DNA polymerase beta. Bidisha Bose-Basu, Eugene F DeRose, Thomas W Kirby, Geoffrey A Mueller, William A Beard, Samuel H Wilson, Robert E London Biochemistry 2004 new
Is DNA polymerase beta important in thermal radiosensitization? G P Raaphorst, D P Yang, G Niedbala Int J Hyperthermia 2004 new
When pol I goes into high gear: processive DNA synthesis by pol I in the cell. Manel Camps, Lawrence A Loeb Cell cycle (Georgetown, Tex.) 2004 new
Mechanism of cell cycle arrest by sulfoquinovosyl monoacylglycerol with a C18-saturated fatty acid (C18-SQMG). Chikako Murakami, Takeshi Miuzno, Fumio Hanaoka, Hiromi Yoshida, Kengo Sakaguchi, Yoshiyuki Mizushina Biochemical pharmacology 2004 new
Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts. Jae Young Lee, Luis Blanco, Tong Zhou, Miguel Garcia-Diaz, Katarzyna Bebenek, Thomas A Kunkel, Zhengqiang Wang, Lawrence F Povirk The Journal of biological chemistry 2004 new
p53 Deficiency rescues neuronal apoptosis but not differentiation in DNA polymerase beta-deficient mice. Noriyuki Sugo, Naoko Niimi, Yasuaki Aratani, Keiko Takiguchi-Hayashi, Hideki Koyama Molecular and cellular biology 2004 new
Relationship between antiviral activity and host toxicity: comparison of the incorporation efficiencies of 2',3'-dideoxy-5-fluoro-3'-thiacytidine-triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondrial DNA polymerase. Joy Y Feng, Eisuke Murakami, Suzana M Zorca, Allison A Johnson, Kenneth A Johnson, Raymond F Schinazi, Phillip A Furman, Karen S Anderson Antimicrobial agents and chemotherapy 2004 new
A role for DNA polymerase V in G --> T mutations from the major benzo[a]pyrene N2-dG adduct when studied in a 5'-TGT sequence in E. coli. Jun Yin, Kwang Young Seo, Edward L Loechler DNA repair 2004 new
Snapshots of replication through an abasic lesion; structural basis for base substitutions and frameshifts. Hong Ling, François Boudsocq, Roger Woodgate, Wei Wen Yang Molecular cell 2004 topics set
DNA polymerase beta lyase inhibitors from Maytenus putterlickoides. Xizhi Feng, Zhijie Gao, Shisheng Li, Shannon H Jones, Sidney M Hecht J Nat Prod 2004 new
The theta subunit of Escherichia coli DNA polymerase III: a role in stabilizing the epsilon proofreading subunit. Sharon A Taft-Benz, Roel M Schaaper J Bacteriol 2004 pols set
PCR amplification of DNA containing non-standard base pairs by variants of reverse transcriptase from Human Immunodeficiency Virus-1. A Michael Sismour, Stefan Lutz, Jeong-Ho Park, Michael J Lutz, Paul L Boyer, Stephen H Hughes, Steven A Benner Nucleic acids research 2004 pols set
Inactivation of the 3'-5' exonuclease of the replicative T4 DNA polymerase allows translesion DNA synthesis at an abasic site. Nicolas Tanguy Le Gac, Emmanuelle Delagoutte, Matthieu Germain, Giuseppe Villani Journal of molecular biology 2004 pols set
A new ursane triterpene from Monochaetum vulcanicum that inhibits DNA polymerase beta lyase. V S Prakash Chaturvedula, Zhijie Gao, Shannon H Jones, Xizhi Feng, Sidney M Hecht, David G I Kingston J Nat Prod 2004 new
Mutations at position 184 of human immunodeficiency virus type-1 reverse transcriptase affect virus titer and viral DNA synthesis. John G Julias, Paul L Boyer, Mary Jane McWilliams, W Gregory Alvord, Stephen H Hughes Virology 2004 pols set
The Pol32 subunit of DNA polymerase delta contains separable domains for processive replication and proliferating cell nuclear antigen (PCNA) binding. Erik Johansson, Parie Garg, Peter M J Burgers The Journal of biological chemistry 2004 pols set
Current status of the non-nucleoside reverse transcriptase inhibitors of human immunodeficiency virus type 1. Jan Balzarini Current topics in medicinal chemistry 2004 pols set
Bacteriophage T4 32 protein is required for helicase-dependent leading strand synthesis when the helicase is loaded by the T4 59 helicase-loading protein. Charles E Jones, Timothy C Mueser, Nancy G Nossal The Journal of biological chemistry 2004 complete
A point mutation within conserved region VI of herpes simplex virus type 1 DNA polymerase confers altered drug sensitivity and enhances replication fidelity. Ying T Hwang, Harmon J Zuccola, Qiaosheng Lu, Charles B C Hwang J Virol 2004 new
The crystal structure of the monomeric reverse transcriptase from Moloney murine leukemia virus. Debanu Das, Millie M Georgiadis Structure (London, England : 1993) 2004 partial results
Variability in the PR and RT genes of HIV-1 isolated from recently infected subjects. Dan Turner, Ariel Roldan, Bluma G Brenner, Daniela D Moisi, Jean-Pierre Routy, Mark A. Wainberg Antiviral chemistry & chemotherapy 2004 pols set
Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing. Deepak T Nair, Robert E Johnson, Satya Prakash, Louise Prakash, Aneel K Aggarwal Nature 2004 pols set
Efficiency, fidelity and enzymatic switching during translesion DNA synthesis. Scott D McCulloch, Robert J Kokoska, Thomas A Kunkel Cell cycle (Georgetown, Tex.) 2004 pols set
Two positively charged residues of phi29 DNA polymerase, conserved in protein-primed DNA polymerases, are involved in stabilisation of the incoming nucleotide. Verónica Truniger, José María Lázaro, Margarita Salas Journal of molecular biology 2004 pols set
Pol iota is a candidate for the mouse pulmonary adenoma resistance 2 locus, a major modifier of chemically induced lung neoplasia. Min Wang, Theodora R Devereux, Haris G Vikis, Scott D McCulloch, Wanda Holliday, Colleen Anna, Yian Wang, Katarzyna Bebenek, Thomas A Kunkel, Kunliang Guan, Ming You Cancer research 2004 new
Persistent expression of chemokine and chemokine receptor RNAs at primary and latent sites of herpes simplex virus 1 infection. W James Cook, Martha F Kramer, Russell M Walker, Timothy J Burwell, Holly A Holman, Donald M Coen, David M Knipe Virology journal 2004 new
Efficient and error-free replication past a minor-groove DNA adduct by the sequential action of human DNA polymerases iota and kappa. M Todd Washington, Irina G Minko, Robert E Johnson, William T Wolfle, Thomas M Harris, R Stephen Lloyd, Satya Prakash, Louise Prakash Molecular and cellular biology 2004 pols set
[Inhibition of anti-sense human telomerase reverse transcriptase (hTERT) retroviral vector on lung cancer cells]. Feng-Jun Tian, Zhi-Yong Wang, Jun-Yi Ma, Yun-Xia Zhao, Wei Lu Ai zheng = Aizheng = Chinese journal of cancer 2004 new
DNA polymerase iota-like activity in crude cell extracts of different mouse organs. Leonid V Gening, A N Petrochenkov, A B Reshetnyak, Ludmila E Andreeva, Vyacheslav Z Tarantul Biochemistry (Mosc) 2004 new
Pre-steady-state kinetic studies of the fidelity and mechanism of polymerization catalyzed by truncated human DNA polymerase lambda. Kevin A Fiala, Wissam Abdel-Gawad, Zucai Suo Biochemistry 2004 pols set
Frequent polymorphism of the mitochondrial DNA polymerase gamma gene (POLG) in patients with normal spermiograms and unexplained subfertility. Martin Jensen, Henrik Leffers, Jørgen H Petersen, Anders Nyboe Andersen, Niels Jørgensen, Elisabeth Carlsen, Tina Kold Jensen, Niels E Skakkebaek, Ewa Rajpert-De Meyts Human reproduction (Oxford, England) 2004 new
A survey of splice variants of the human hypoxanthine phosphoribosyl transferase and DNA polymerase beta genes: products of alternative or aberrant splicing? Adonis Skandalis, Elke Uribe Nucleic acids research 2004 new
Foscarnet used in salvage therapy of HIV-1 patients harbouring multiple nucleotide excision mutations. Sofie Mathiesen, Birgit T Roge, Nina Weis, Jens D Lundgren, Niels Obel, Jan Gerstoft Aids 2004 new
Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase iota. Antonio E Vidal, Patricia L Kannouche, Vladimir N Podust, Wei Wen Yang, Alan R Lehmann, Roger Woodgate The Journal of biological chemistry 2004 pols set
DNA polymerase fidelity: kinetics, structure, and checkpoints. Catherine M Joyce, Stephen J Benkovic Biochemistry 2004 complete
PCR-based detection of minority point mutations. G Mike Makrigiorgos Human mutation 2004 topics set
Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7. Yingqian Li, Shuchismita Dutta, Sylvie Doublié, Hussam Moh'd Bdour, John-Stephen Taylor, Tom Ellenberger Nature structural & molecular biology 2004 topics set
A DNA polymerase beta mutant from colon cancer cells induces mutations. Tieming Lang, Mausumi Maitra, Daniela Starcevic, Shu-Xia Li, Joann B Sweasy Proceedings of the National Academy of Sciences of the United States of America 2004 new
Increased single-nucleotide discrimination of PCR by primer probes bearing hydrophobic 4'C modifications. Michael Strerath, Jens Gaster, Daniel Summerer, Andreas Marx Chembiochem : a European journal of chemical biology 2004 new
Characterization of the polymerase and RNase H activities of human foamy virus reverse transcriptase. Paul L Boyer, Carolyn R Stenbak, Patrick K Clark, Maxine L Linial, Stephen H Hughes Journal of virology 2004 new
Residues of human cytomegalovirus DNA polymerase catalytic subunit UL54 that are necessary and sufficient for interaction with the accessory protein UL44. Arianna Loregian, Brent A Appleton, James M Hogle, Donald M Coen J Virol 2004 complete Donald M Coen*
Repeated GenomiPhi, phi29 DNA polymerase-based rolling circle amplification, is useful for generation of large amounts of plasmid DNA. Masahiro Sato, Masato Ohtsuka, Yuhsuke Ohmi Nucleic Acids Symp Ser (Oxf) 2004 pols set
Novel mechanism of inhibition of HIV-1 reverse transcriptase by a new non-nucleoside analog, KM-1. Louise Z Wang, George L Kenyon, Kenneth A Johnson The Journal of biological chemistry 2004 new
Plant DNA polymerase lambda, a DNA repair enzyme that functions in plant meristematic and meiotic tissues. Yukinobu Uchiyama, Seisuke Kimura, Taichi Yamamoto, Toyotaka Ishibashi, Kengo Sakaguchi Eur J Biochem 2004 new
Function of the C-terminus of phi29 DNA polymerase in DNA and terminal protein binding. Verónica Truniger, José María Lázaro, Margarita Salas Nucleic acids research 2004 pols set
Involvement of an X family DNA polymerase in double-stranded break repair in the radioresistant organism Deinococcus radiodurans. François Lecointe, Igor V Shevelev, Adriana Bailone, Suzanne Sommer, Ulrich Hübscher Molecular microbiology 2004 new
The D246V mutant of DNA polymerase beta misincorporates nucleotides: evidence for a role for the flexible loop in DNA positioning within the active site. Shibani Dalal, Jessica L Kosa, Joann B Sweasy The Journal of biological chemistry 2004 new
Biochemical association of poly(ADP-ribose) polymerase-1 and its apoptotic peptide fragments with DNA polymerase beta. Nils F Confer, Sunitha R Kumari, Rafael Alvarez-Gonzalez Chem Biodivers 2004 new
Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly. Linjing Yang, Karunesh Arora, William A Beard, Samuel H Wilson, Tamar Schlick Journal of the American Chemical Society 2004 topics set
DNA polymerase delta, RFC and PCNA are required for repair synthesis of large looped heteroduplexes in Saccharomyces cerevisiae. Stephanie E Corrette-Bennett, Claudia Borgeson, Debbie Sommer, Peter M J Burgers, Robert S Lahue Nucleic acids research 2004 new
Proofreading activity of Pfu thermostable DNA polymerase on a 6-O-methylguanine-containing template monitored by ESI-FTICR mass spectrometry. David S Wunschel, Christophe Masselon, Bingbing Feng, Richard W P Smith Chembiochem 2004 new
Binding of phage Phi29 architectural protein p6 to the viral genome: evidence for topological restriction of the phage linear DNA. Víctor González-Huici, Martín Alcorlo, Margarita Salas, José M Hermoso Nucleic acids research 2004 pols set
DNA-thumb interactions and processivity of T7 DNA polymerase in comparison to yeast polymerase eta. Vincent J Cannistraro, John-Stephen Taylor The Journal of biological chemistry 2004 pols set
Translesion DNA synthesis: little fingers teach tolerance. Oliver Fleck, Primo Schär Current biology : CB 2004 topics set
DNA polymerase lambda can elongate on DNA substrates mimicking non-homologous end joining and interact with XRCC4-ligase IV complex. Wei Fan, Xiaoming Wu Biochem Biophys Res Commun 2004 new
DNA polymerase beta mRNA and protein expression in Xiphophorus fish. Sheila J Heater, Leon P Oehlers, J Douglas Rains, Ronald B Walter Comp Biochem Physiol C Toxicol Pharmacol 2004 new
Dehydrotrametenonic acid and dehydroeburiconic acid from Poria cocos and their inhibitory effects on eukaryotic DNA polymerase alpha and beta. Toshihiro Akihisa, Yoshiyuki Mizushina, Motohiko Ukiya, Manabu Oshikubo, Seizo Kondo, Yumiko Kimura, Takashi Suzuki, Takaaki Tai Biosci Biotechnol Biochem 2004 new
Is there a link between DNA polymerase beta and cancer? Daniela Starcevic, Shibani Dalal, Joann B Sweasy Cell Cycle 2004 new
Structural and thermodynamic analysis of human PCNA with peptides derived from DNA polymerase-delta p66 subunit and flap endonuclease-1. John B Bruning, Yousif Shamoo Structure (London, England : 1993) 2004 new
On the role of proofreading exonuclease in bypass of a 1,2 d(GpG) cisplatin adduct by the herpes simplex virus-1 DNA polymerase. Mercedes E Arana, Liping Song, Nicolas Tanguy Le Gac, Deborah S Parris, Giuseppe Villani, Paul E Boehmer DNA repair 2004 new
Overexpression of human DNA polymerase mu (Pol mu) in a Burkitt's lymphoma cell line affects the somatic hypermutation rate. José F Ruiz, Daniel Lucas, Esther García-Palomero, Ana I Saez, Manuel A González, Miguel A Piris, Antonio Bernad, Luis Blanco Nucleic acids research 2004 pols set
Taxol derivatives are selective inhibitors of DNA polymerase alpha. Masahiko Oshige, Mika Takenouchi, Yasutaro Kato, Shinji Kamisuki, Toshifumi Takeuchi, Kouji Kuramochi, Isamu Shiina, Yoshihito Suenaga, Yo-ichi Kawakita, Kazufumi Kuroda, Noriyuki Sato, Susumu Kobayashi, Fumio Sugawara, Kengo Sakaguchi Bioorg Med Chem 2004 pols set
Expanding the substrate repertoire of a DNA polymerase by directed evolution. Ming Fa, Annalisa Radeghieri, Allison A Henry, Floyd E Romesberg Journal of the American Chemical Society 2004 new
In vitro characterization of a simian immunodeficiency virus-human immunodeficiency virus (HIV) chimera expressing HIV type 1 reverse transcriptase to study antiviral resistance in pigtail macaques. Zandrea Ambrose, Valerie Boltz, Sarah Palmer, John M Coffin, Stephen H Hughes, Vineet N Kewalramani Journal of virology 2004 pols set
Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. Kevin A Fiala, Zucai Suo Biochemistry 2004 partial results
Crystal structure of the chi:psi sub-assembly of the Escherichia coli DNA polymerase clamp-loader complex. Jacqueline M Gulbis, Steven L Kazmirski, Jeff Finkelstein, Zvi Kelman, Mike E O'Donnell, John Kuriyan Eur J Biochem 2004 topics set
Human herpesvirus 6 DNA polymerase: enzymatic parameters, sensitivity to ganciclovir and determination of the role of the A961V mutation in HHV-6 ganciclovir resistance. Leen De Bolle, Chaysavanh Manichanh, Henri Agut, Erik De Clercq, Lieve Naesens Antiviral Res 2004 new
Inhibition of Taq DNA polymerase by catalpol. Carlos Rodolfo Pungitore, M Juri Ayub, Eduardo J Borkowski, Carlos E Tonn, G M Ciuffo Cell Mol Biol (Noisy-le-grand) 2004 pols set
Effects of primer-template sequence on ATP-dependent removal of chain-terminating nucleotide analogues by HIV-1 reverse transcriptase. Peter R Meyer, Anthony J Smith, Suzanne E Matsuura, Walter A Scott The Journal of biological chemistry 2004 pols set
Enzymatic production of RNAi libraries from cDNAs. Daisuke Shirane, Kohtaroh Sugao, Shigeyuki Namiki, Mao Tanabe, Masamitsu Iino, Kenzo Hirose Nat Genet 2004 topics set
Analyzing the handoff of DNA from UvrA to UvrB utilizing DNA-protein photoaffinity labeling. Matthew J DellaVecchia, Deborah L Croteau, Milan Skorvaga, Sergey V Dezhurov, Olga I Lavrik, Bennett Van Houten The Journal of biological chemistry 2004 new
Effects of mutations in the G tract of the human immunodeficiency virus type 1 polypurine tract on virus replication and RNase H cleavage. John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes J Virol 2004 pols set
Dependence of DNA polymerase replication rate on external forces: a model based on molecular dynamics simulations. Ioan Andricioaei, Anita Goel, Dudley Herschbach, Martin Karplus Biophys J 2004 new
Roles of conformational and positional adaptability in structure-based design of TMC125-R165335 (etravirine) and related non-nucleoside reverse transcriptase inhibitors that are highly potent and effective against wild-type and drug-resistant HIV-1 variants. Kalyan Das, Arthur D Clark, Paul J Lewi, Jan Heeres, Marc R De Jonge, Lucien M H Koymans, H Maarten Vinkers, Frederik Daeyaert, Donald W Ludovici, Michael J Kukla, Bart De Corte, Robert W Kavash, Chih Y Ho, Hong Ye, Mark A Lichtenstein, Koen Andries, Rudi Pauwels, Marie-Pierre P De Béthune, Paul L Boyer, Patrick K Clark, Stephen H Hughes, Paul A J Janssen, Edward Arnold J Med Chem 2004 partial results
Translesion synthesis past equine estrogen-derived 2'-deoxycytidine DNA adducts by human DNA polymerases eta and kappa. Naomi Suzuki, Manabu Yasui, Y R Santosh Laxmi, Haruo Ohmori, Fumio Hanaoka, Shinya Shibutani Biochemistry 2004 pols set
DNA binding properties of human DNA polymerase eta: implications for fidelity and polymerase switching of translesion synthesis. Rika Kusumoto, Chikahide Masutani, Shizu Shimmyo, Shigenori Iwai, Fumio Hanaoka Genes Cells 2004 pols set
Diversity of structure and function of DNA polymerase (gp43) of T4-related bacteriophages. Vasiliy M Petrov, Jim D Karam Biochemistry (Mosc) 2004 complete
Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein. Yasuteru Sano, Hidetoshi Date, Shuichi Igarashi, Osamu Onodera, Mutsuo Oyake, Tomosaburo Takahashi, Shintaro Hayashi, Mitsunori Morimatsu, Hitoshi Takahashi, Takao Makifuchi, Nobuyoshi Fukuhara, Shoji Tsuji Annals of neurology 2004 new
AP endonuclease and poly(ADP-ribose) polymerase-1 interact with the same base excision repair intermediate. Cheryl Cistulli, Olga I Lavrik, Rajendra Prasad, Esther W Hou, Samuel H Wilson DNA repair 2004 new
The C-terminal zinc finger of the catalytic subunit of DNA polymerase delta is responsible for direct interaction with the B-subunit. Javier Sanchez Garcia, Leonora F Ciufo, Xiaowen Yang, Stephen E Kearsey, Stuart A MacNeill Nucleic acids research 2004 new
Crystallographic snapshots of a replicative DNA polymerase encountering an abasic site. Matthew Hogg, Susan S Wallace, Sylvie Doublié The EMBO journal 2004 topics set
Designing anti-AIDS drugs targeting the major mechanism of HIV-1 RT resistance to nucleoside analog drugs. Stefan G Sarafianos, Stephen H Hughes, Edward Arnold Int J Biochem Cell Biol 2004 topics set
The phenylmethylthiazolylthiourea nonnucleoside reverse transcriptase (RT) inhibitor MSK-076 selects for a resistance mutation in the active site of human immunodeficiency virus type 2 RT. Joeri Auwerx, Miguel Stevens, An R Van Rompay, Louise E Bird, Jingshan Ren, Erik De Clercq, Bo Oberg, David K Stammers, Anna Karlsson, Jan Balzarini Journal of virology 2004 pols set
Functions of DNA polymerases. Katarzyna Bebenek, Thomas A Kunkel Adv Protein Chem 2004 topics set
Iridoids as allelochemicals and DNA polymerase inhibitors. Carlos Rodolfo Pungitore, Maximiliano Juri Ayub, Matías García, Eduardo J Borkowski, Marta E Sosa, Gladys Ciuffo, Oscar S Giordano, Carlos E Tonn J Nat Prod 2004 new
[Hepatitis B virus specific DNA polymerase activity as a sensitive marker of viral replication]. Kazuharu Matsuura, Kazuo Tobe Nippon Rinsho 2004 new
Structure of a bifunctional DNA primase-polymerase. G Lipps, AO Weinzierl, G von Scheven, C Buchen, P Cramer Nature structural & molecular biology 2004 topics set
Relationships among various nucleoside resistance-conferring mutations in the reverse transcriptase of HIV-1. Dan Turner, Bluma G Brenner, Mark A. Wainberg The Journal of antimicrobial chemotherapy 2004 pols set
Cellular functions of DNA polymerase zeta and Rev1 protein. Christopher W Lawrence Adv Protein Chem 2004 topics set
Mcm10 regulates the stability and chromatin association of DNA polymerase-alpha. Robin M Ricke, Anja-Katrin Bielinsky Molecular cell 2004 complete Anja-Katrin Bielinsky*
Poly(ADP-ribose) polymerase-1 inhibits strand-displacement synthesis of DNA catalyzed by DNA polymerase beta. Maria V Sukhanova, Svetlana N Khodyreva, Olga I Lavrik Biochemistry. Biokhimii͡a 2004 new
Proteolytic processing of an HIV-1 pol polyprotein precursor: insights into the mechanism of reverse transcriptase p66/p51 heterodimer formation. Nicolas Sluis-Cremer, Dominique Arion, Michael E Abram, Michael A. Parniak The international journal of biochemistry & cell biology 2004 pols set
DNA polymerase beta overexpression stimulates the Rad51-dependent homologous recombination in mammalian cells. Yvan Canitrot, Jean-Pascal Capp, Nadine Puget, Anne Bieth, Bernard S Lopez, Jean-Sébastien Hoffmann, Christophe Cazaux Nucleic acids research 2004 new
Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase. Luis G Brieba, Brandt F Eichman, Robert J Kokoska, Sylvie Doublié, Thomas A Kunkel, Tom Ellenberger The EMBO journal 2004 topics set
Translesion synthesis by human DNA polymerase eta across oxidative products of guanine. Katuhito Kino, Nobutoshi Ito, Kaoru Sugasawa, Hiroshi Sugiyama, Fumio Hanaoka Nucleic Acids Symp Ser (Oxf) 2004 pols set
AP endonuclease-independent DNA base excision repair in human cells. Lee Wiederhold, John B Leppard, Padmini S Kedar, Feridoun Karimi-Busheri, Aghdass Rasouli-Nia, Michael Weinfeld, Alan E Tomkinson, Tadahide Izumi, Rajendra Prasad, Samuel H Wilson, Sankar Mitra, Tapas K Hazra Molecular cell 2004 new
Gln145Met/Leu changes in human immunodeficiency virus type 1 reverse transcriptase confer resistance to nucleoside and nonnucleoside analogs and impair virus replication. Stefania Paolucci, Fausto Baldanti, Giovanni Maga, Reynel Cancio, Maurizio Zazzi, Maurizio Zavattoni, Antonella Chiesa, Silvio Spadari, Giuseppe Gerna Antimicrobial agents and chemotherapy 2004 pols set
Biochemical and mechanistic basis for the activity of nucleoside analogue inhibitors of HIV reverse transcriptase. George R Painter, Merrick R Almond, Shuli Mao, Dennis C Liotta Curr Top Med Chem 2004 partial results
XRCC1-DNA polymerase beta interaction is required for efficient base excision repair. Irina I Dianova, Kate M Sleeth, Sarah L Allinson, Jason L Parsons, Claire Breslin, Keith W Caldecott, Grigory L Dianov Nucleic acids research 2004 new
Role of the Escherichia coli RecQ DNA helicase in SOS signaling and genome stabilization at stalled replication forks. Takashi Hishida, Yong-Woon Han, Tatsuya Shibata, Yoshino Kubota, Yoshizumi Ishino, Hiroshi Iwasaki, Hideo Shinagawa Genes & development 2004 new
The impact of the M184V substitution on drug resistance and viral fitness. Mark A. Wainberg Expert review of anti-infective therapy 2004 pols set
The role of DNA polymerase eta in translesion synthesis past platinum-DNA adducts in human fibroblasts. Ekaterina Bassett, Nicole M King, Miriam F Bryant, Suzanne Hector, Lakshmi Pendyala, Stephen G Chaney, Marila Cordeiro-Stone Cancer research 2004 new
Role of base stacking and sequence context in the inhibition of yeast DNA polymerase eta by pyrene nucleotide. Hanshin Hwang, John-Stephen Taylor Biochemistry 2004 new
Distinct pools of proliferating cell nuclear antigen associated to DNA replication sites interact with the p125 subunit of DNA polymerase delta or DNA ligase I. Federica Riva, Monica Savio, Ornella Cazzalini, Lucia A Stivala, Ivana A Scovassi, Lynne S Cox, Bernard Ducommun, Ennio Prosperi Exp Cell Res 2004 new
Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir. Steve Tuske, Stefan G Sarafianos, Arthur D Clark, Jianping Ding, Lisa K Naeger, Kirsten L White, Michael D Miller, Craig S Gibbs, Paul L Boyer, Patrick K Clark, Gang Wang, Barbara L Gaffney, Roger A Jones, Donald M Jerina, Stephen H Hughes, Edward Arnold Nature structural & molecular biology 2004 topics set
Excision of incorporated nucleotide analogue chain-terminators can diminish their inhibitory effects on viral RNA-dependent RNA polymerases. Claudia M D'Abramo, Luciano Cellai, Matthias Götte Journal of molecular biology 2004 pols set
Functional analysis of multiple single-stranded DNA-binding proteins from Methanosarcina acetivorans and their effects on DNA synthesis by DNA polymerase BI. Justin B Robbins, Mary C Murphy, Bryan A White, Roderick I Mackie, Taekjip Ha, Isaac K O Cann The Journal of biological chemistry 2004 new
A biochemically defined system for mammalian nonhomologous DNA end joining. Yunmei Ma, Haihui Lu, Brigette Tippin, Myron F Goodman, Noriko Shimazaki, Osamu Koiwai, Chih-Lin Hsieh, Klaus Schwarz, Michael R Lieber Molecular cell 2004 topics set
Lesion (in)tolerance reveals insights into DNA replication fidelity. Eva Freisinger, Arthur P Grollman, Holly Miller, Caroline Kisker The EMBO journal 2004 topics set
Idling by DNA polymerase delta maintains a ligatable nick during lagging-strand DNA replication. Parie Garg, Carrie M W Stith, Nasim Sabouri, Erik Johansson, Peter M J Burgers Genes Dev 2004 new
Reverse transcriptase activity of hepatitis B virus (HBV) DNA polymerase within core capsid: interaction with deoxynucleoside triphosphates and anti-HBV L-deoxynucleoside analog triphosphates. Wing Lam, Yingqian Li, Jieh-Yuan Liou, Ginger E Dutschman, Yung-Chi Cheng Mol Pharmacol 2004 topics set
Pre-steady-state kinetics of RB69 DNA polymerase and its exo domain mutants: effect of pH and thiophosphoryl linkages on 3'-5' exonuclease activity. C X Wang, E Zakharova, Jinming Li, Catherine M Joyce, Jianhong Wang, William H Konigsberg Biochemistry 2004 complete
The highly processive DNA polymerase of bacteriophage T5. Role of the unique N and C termini. Nathalie Andraos, Stanley Tabor, Charles C Richardson The Journal of biological chemistry 2004 new
Nucleoside-analog resistance mutations in HIV-1 reverse transcriptase and their influence on polymerase fidelity and viral mutation rates. Lisa F Rezende, Vinayaka R Prasad Int J Biochem Cell Biol 2004 partial results
Subunit-specific analysis of the human immunodeficiency virus type 1 reverse transcriptase in vivo. Alok Mulky, Stefan G Sarafianos, Edward Arnold, Xiaoming Wu, John C Kappes J Virol 2004 new
Escherichia coli DNA polymerase I (Klenow fragment) uses a hydrogen-bonding fork from Arg668 to the primer terminus and incoming deoxynucleotide triphosphate to catalyze DNA replication. Aviva S Meyer, Maureen Blandino, Thomas E Spratt The Journal of biological chemistry 2004 topics set
Aphidicolin-resistant and -sensitive base excision repair in wild-type and DNA polymerase beta-defective mouse cells. Eleonora Parlanti, Barbara Pascucci, Gloria Terrados, Luis Blanco, Eugenia Dogliotti DNA repair 2004 new
Switching from high-fidelity replicases to low-fidelity lesion-bypass polymerases. Brian S Plosky, Roger Woodgate Curr Opin Genet Dev 2004 topics set
Antiviral profile of HIV inhibitors in macrophages: implications for therapy. CF Perno, Emanuela Balestra, M Francesconi, D Abdelahad, Raffaele Caliò, Jan Balzarini, Stefano Aquaro Current topics in medicinal chemistry 2004 pols set
Analysis of the effect of bulk at N2-alkylguanine DNA adducts on catalytic efficiency and fidelity of the processive DNA polymerases bacteriophage T7 exonuclease- and HIV-1 reverse transcriptase. Jeong-Yun Choi, F Peter Guengerich The Journal of biological chemistry 2004 pols set
Gene structure, purification and characterization of DNA polymerase beta from Xiphophorus maculatus. Leon P Oehlers, Sheila J Heater, J Douglas Rains, Melissa C Wells, Wendi M David, Ronald B Walter Comp Biochem Physiol C Toxicol Pharmacol 2004 new
DNA polymerase-catalyzed elongation of repetitive hexanucleotide sequences: application to creation of repetitive DNA libraries. Hiroyuki Kurihara, Teruyuki Nagamune Biotechnol Prog 2004 new
TSAO compounds: the comprehensive story of a unique family of HIV-1 specific inhibitors of reverse transcriptase. María-José Camarasa, Ana San-Félix, Sonsoles Velázquez, María-Jesús Pérez-Pérez, Federico Gago, Jan Balzarini Current topics in medicinal chemistry 2004 pols set
Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations. Youri I Pavlov, Satoko Maki, Hisaji Maki, Thomas A Kunkel BMC biology 2004 partial results
5-Alkyl-2-[(aryl and alkyloxylcarbonylmethyl)thio]-6-(1-naphthylmethyl) pyrimidin-4(3H)-ones as an unique HIV reverse transcriptase inhibitors of S-DABO series. Yanping He, Fener Chen, Guangfu Sun, Yueping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Bioorganic & medicinal chemistry letters 2004 pols set
Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination. Kenji Watanabe, Satoshi Tateishi, Michio Kawasuji, Toshiki Tsurimoto, Hirokazu Inoue, Masaru Yamaizumi The EMBO journal 2004 topics set
The arginine finger of bacteriophage T7 gene 4 helicase: role in energy coupling. DJ Crampton, S Guo, Donald E Johnson, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 2004 topics set
Quantitative analysis of translesion DNA synthesis across a benzo[a]pyrene-guanine adduct in mammalian cells: the role of DNA polymerase kappa. Sharon Avkin, Moshe Goldsmith, Susana Velasco-Miguel, Nicholas E Geacintov, Errol C Friedberg, Zvi Livneh The Journal of biological chemistry 2004 new
Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase. Hong Ling, Jane M Sayer, Brian S Plosky, Haruhiko Yagi, François Boudsocq, Roger Woodgate, Donald M Jerina, Wei Wen Yang Proceedings of the National Academy of Sciences of the United States of America 2004 topics set
DNA mutagenesis using T4 DNA polymerase and DpnI restriction endonuclease. Wen Xin, Da-Wei Huang, Yi-Ming Zhang, Liang Geng Anal Biochem 2004 pols set
Identification of small molecule synthetic inhibitors of DNA polymerase beta by NMR chemical shift mapping. Hong-Yu Hu, Julie K Horton, Michael R Gryk, Rajendra Prasad, Jana M Naron, Di-An Sun, Sidney M Hecht, Samuel H Wilson, Gregory P Mullen The Journal of biological chemistry 2004 new
Human DNA polymerase iota utilizes different nucleotide incorporation mechanisms dependent upon the template base. M Todd Washington, Robert E Johnson, Louise Prakash, Satya Prakash Molecular and cellular biology 2004 pols set
Contribution of the 3'- to 5'-exonuclease activity of herpes simplex virus type 1 DNA polymerase to the fidelity of DNA synthesis. Liping Song, Murari Chaudhuri, Charles W Knopf, Deborah S Parris The Journal of biological chemistry 2004 new
Low-fidelity Pyrococcus furiosus DNA polymerase mutants useful in error-prone PCR. Benjamin D Biles, Bernard A Connolly Nucleic acids research 2004 topics set
Unusual codon 69 insertions: influence on human immunodeficiency virus type 1 reverse transcriptase drug susceptibility. Elisabetta Bulgheroni, Francesco Croce, Paola Citterio, Ottavia Viganò, Raffaella Visonà, Eugenio Sala, Massimo Galli, Stefano Rusconi Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2004 pols set
Mechanism of DNA polymerization catalyzed by Sulfolobus solfataricus P2 DNA polymerase IV. Kevin A Fiala, Zucai Suo Biochemistry 2004 topics set
Premature ageing in mice expressing defective mitochondrial DNA polymerase. Aleksandra Trifunovic, Anna Wredenberg, Maria Falkenberg, Johannes N Spelbrink, Anja T Rovio, Carl E Bruder, Mohammad Bohlooly-Y, Sebastian Gidlöf, Anders Oldfors, Rolf Wibom, Jan Törnell, Howard T Jacobs, Nils-Göran Larsson Nature 2004 new
The dynamic processivity of the T4 DNA polymerase during replication. Jingsong Yang, Zhihao Zhuang, Rosa Maria Roccasecca, Michael A Trakselis, Stephen J Benkovic Proceedings of the National Academy of Sciences of the United States of America 2004 partial results
Translesion synthesis of acetylaminofluorene-dG adducts by DNA polymerase zeta is stimulated by yeast Rev1 protein. Dongyu Guo, Zhongwen Xie, Huiyun Shen, Bo Zhao, Zhengqiang Wang Nucleic acids research 2004 new
Nonnucleoside inhibitor binding affects the interactions of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase with DNA. Elena N Peletskaya, Alex A Kogon, Steven Tuske, Edward Arnold, Stephen H Hughes J Virol 2004 partial results
Telomerase reverse transcriptase gene amplification in hepatocellular carcinoma. Yoshitaka Takuma, Kazuhiro Nouso, Yoshiyuki Kobayashi, Shinichiro Nakamura, Hiromichi Tanaka, Eiji Matsumoto, Tatsuya Fujikawa, Motoshi Suzuki, Tadashi Hanafusa, Yasushi Shiratori Journal of gastroenterology and hepatology 2004 new
Structure-function defects of human mitochondrial DNA polymerase in autosomal dominant progressive external ophthalmoplegia. Maria A Graziewicz, Matthew J Longley, Rachelle J Bienstock, Massimo Zeviani, William C Copeland Nature structural & molecular biology 2004 pols set
Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1. Andrew L Hopkins, Jingshan Ren, John Milton, Richard J Hazen, Joseph H Chan, David I Stuart, David K Stammers J Med Chem 2004 complete David K Stammers*
Physiological and biochemical defects in functional interactions of mitochondrial DNA polymerase and DNA-binding mutants of single-stranded DNA-binding protein. Carol L Farr, Yuichi Matsushima, Anthony T Lagina, Ningguang Luo, Laurie S Kaguni The Journal of biological chemistry 2004 new
Resistance issues with new nucleoside/nucleotide backbone options. Mark A. Wainberg, Dan Turner Journal of acquired immune deficiency syndromes 2004 new
Protein trafficking on sliding clamps. Francisco López de Saro, Roxana E Georgescu, Frank Leu, Mike E O'Donnell Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2004 topics set
DNA polymerase theta is preferentially expressed in lymphoid tissues and upregulated in human cancers. Kiyoko Kawamura, Rumana Bahar, Mika Seimiya, Masako Chiyo, Akihiko Wada, Seiji Okada, Masahiko Hatano, Takeshi Tokuhisa, Hiroshi Kimura, Satoshi Watanabe, Ichiro Honda, Shigeru Sakiyama, Masatoshi Tagawa, Jiyang O-Wang Int J Cancer 2004 new
'Knock down' of DNA polymerase beta by RNA interference: recapitulation of null phenotype. Yaroslava Y Polosina, Thomas A Rosenquist, Arthur P Grollman, Holly Miller DNA repair 2004 new
Development of a novel solvatochromic pyrimidine analog for probing local dielectric environment of DNA polymerase. Kazuki Tainaka, Akimitsu Okamoto, Isao Saito Nucleic acids symposium series (2004) 2004 topics set
A 4'-C-ethynyl-2',3'-dideoxynucleoside analogue highlights the role of the 3'-OH in anti-HIV active 4'-C-ethynyl-2'-deoxy nucleosides. Maqbool A Siddiqui, Stephen H Hughes, Paul L Boyer, Hiroyuki Mitsuya, Que N Van, Clifford George, Stefan G Sarafinanos, Victor E Marquez J Med Chem 2004 topics set
phi29 DNA polymerase-terminal protein interaction. Involvement of residues specifically conserved among protein-primed DNA polymerases. Irene Rodríguez, José María Lázaro, Margarita Salas, Miguel de Vega Journal of molecular biology 2004 pols set
A unique region in bacteriophage t7 DNA polymerase important for exonucleolytic hydrolysis of DNA. Jaya K Kumar, Erica T Chiu, Stanley Tabor, Charles C Richardson The Journal of biological chemistry 2004 pols set
A loss of viral replicative capacity correlates with altered DNA polymerization kinetics by the human immunodeficiency virus reverse transcriptase bearing the K65R and L74V dideoxynucleoside resistance substitutions. Jérôme Deval, Jean-Marc Navarro, Boulbaba Selmi, Jérôme Courcambeck, Joëlle Boretto, Philippe Halfon, Sarah Garrido-Urbani, Josephine Sire, Bruno Canard The Journal of biological chemistry 2004 topics set
Role of Escherichia coli DNA polymerase IV in in vivo replication fidelity. Wojciech Kuban, Piotr Jonczyk, Damian Gawel, Karolina Malanowska, Roel M Schaaper, I Fijalkowska J Bacteriol 2004 pols set
Efficient and error-free replication past a minor-groove N2-guanine adduct by the sequential action of yeast Rev1 and DNA polymerase zeta. M Todd Washington, Irina G Minko, Robert E Johnson, Lajos Haracska, Thomas M Harris, R Stephen Lloyd, Satya Prakash, Louise Prakash Molecular and cellular biology 2004 new
Comparative kinetics of nucleotide analog incorporation by vent DNA polymerase. Andrew F Gardner, Catherine M Joyce, William E Jack The Journal of biological chemistry 2004 partial results
A coordinated temporal interplay of nucleosome reorganization factor, sister chromatin cohesion factor, and DNA polymerase alpha facilitates DNA replication. Yanjiao Zhou, Teresa S-F Wang Molecular and cellular biology 2004 new
Diminished representation of HIV-1 variants containing select drug resistance-conferring mutations in primary HIV-1 infection. Dan Turner, Bluma G Brenner, Jean-Pierre Routy, Daniela D Moisi, Zeev Rosberger, Michel Roger, Mark A. Wainberg Journal of acquired immune deficiency syndromes 2004 pols set
Enzymatic synthesis of phosphoroselenoate DNA using thymidine 5'-(alpha-P-seleno)triphosphate and DNA polymerase for X-ray crystallography via MAD. Nicolas Carrasco, Zhen Huang Journal of the American Chemical Society 2004 new
Identification of a small molecule that inhibits herpes simplex virus DNA Polymerase subunit interactions and viral replication. Beatrice D Pilger, Can Cui, Donald M Coen Chemistry & biology 2004 complete Donald M Coen*
A novel nuclear protein, MGC5306 interacts with DNA polymerase beta and has a potential role in cellular phenotype. Liming Wang, Nandan Bhattacharyya, Diane M Chelsea, Pedro F Escobar, Sanjeev Banerjee Cancer research 2004 new
The B-subunit of DNA polymerase alpha-primase associates with the origin recognition complex for initiation of DNA replication. Masashi Uchiyama, Teresa S-F Wang Molecular and cellular biology 2004 new
The clamp-loading complex for processive DNA replication. Tomoko Miyata, Takuji Oyama, Kouta Mayanagi, Sonoko Ishino, Yoshizumi Ishino, Kosuke Morikawa Nature structural & molecular biology 2004 new
New neolignans that inhibit DNA polymerase beta lyase. V S Prakash Chaturvedula, Sidney M Hecht, Zhijie Gao, Shannon H Jones, Xizhi Feng, David G I Kingston J Nat Prod 2004 new
2-(2,6-Dihalophenyl)-3-(pyrimidin-2-yl)-1,3-thiazolidin-4-ones as non-nucleoside HIV-1 reverse transcriptase inhibitors. Angela Rao, Jan Balzarini, Anna Carbone, Alba Chimirri, Erik De Clercq, Anna-Maria Monforte, Pietro Monforte, Christophe Pannecouque, Maria Zappalà Antiviral research 2004 pols set
Non-nucleoside reverse transcriptase inhibitors (NNRTIs): past, present, and future. Erik De Clercq Chemistry & biodiversity 2004 pols set
In situ analysis of repair processes for oxidative DNA damage in mammalian cells. Li Lan, Satoshi Nakajima, Yoshitsugu Oohata, Masashi Takao, Satoshi Okano, Mitsuko Masutani, Samuel H Wilson, Akira Yasui Proceedings of the National Academy of Sciences of the United States of America 2004 new
A molecular handoff between bacteriophage T7 DNA primase and T7 DNA polymerase initiates DNA synthesis. Masato Kato, Takuhiro Ito, Gerhard Wagner, Tom Ellenberger The Journal of biological chemistry 2004 pols set
Mechanistic basis for reduced viral and enzymatic fitness of HIV-1 reverse transcriptase containing both K65R and M184V mutations. Jérôme Deval, Kirsten L White, Michael D Miller, Neil T Parkin, Jérôme Courcambeck, Philippe Halfon, Boulbaba Selmi, Joëlle Boretto, Bruno Canard The Journal of biological chemistry 2004 topics set
The herpes simplex virus processivity factor, UL42, binds DNA as a monomer. John C W Randell, Donald M Coen Journal of molecular biology 2004 new
Orchestration of cooperative events in DNA synthesis and repair mechanism unraveled by transition path sampling of DNA polymerase beta's closing. Ravi Radhakrishnan, Tamar Schlick Proceedings of the National Academy of Sciences of the United States of America 2004 new
Identification of specific amino acid residues in the E. coli beta processivity clamp involved in interactions with DNA polymerase III, UmuD and UmuD'. Jill M Duzen, Graham C Walker, Mark D Sutton DNA repair 2004 new
Accuracy, lesion bypass, strand displacement and translocation by DNA polymerases. Thomas A Steitz, Y Whitney Yin Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2004 new
Chemical synthesis and translesion replication of a cis-syn cyclobutane thymine-uracil dimer. Kohei Takasawa, Chikahide Masutani, Fumio Hanaoka, Shigenori Iwai Nucleic acids research 2004 pols set
DNA polymerase eta is involved in hypermutation occurring during immunoglobulin class switch recombination. Ahmad Faili, Said Aoufouchi, Sandra Weller, Françoise Vuillier, Anne Stary, Alain Sarasin, Claude-Agnès Reynaud, Jean-Claude Weill J Exp Med 2004 new
Mutations and polymorphisms associated with antiretroviral drugs in HIV-1C-infected African patients. Florence Doualla-Bell, Simane Gaseitsiwe, Thumbi Ndungú, Musetsanagepe Modukanele, Trevor Peter, Vladimir Novitsky, Ndwapi Ndwapi, Gaolathe Tendani, Ava Avalos, William Wester, Hermann Bussmann, Peter Cardiello, Richard G Marlink, Howard Moffat, Ibou Thior, Mark A. Wainberg, Max Essex Antiviral chemistry & chemotherapy 2004 pols set
Synthesis of new 2,3-diaryl-1,3-thiazolidin-4-ones as anti-HIV agents. Angela Rao, Jan Balzarini, Anna Carbone, Alba Chimirri, Erik De Clercq, Anna Maria Monforte, Pietro Monforte, Christophe Pannecouque, Maria Zappalà Farmaco (Società chimica italiana : 1989) 2004 pols set
Nucleocytoplasmic lectins. John L Wang, Richard M Gray, Kevin C Haudek, Ronald J Patterson Biochimica et biophysica acta 2004 new
Multicopy plasmids affect replisome positioning in Bacillus subtilis. Jue D Wang, Megan E Rokop, Melanie M Barker, Nathaniel R Hanson, Alan D Grossman Journal of bacteriology 2004 complete Alan D Grossman*
Molecular mechanisms of tenofovir resistance conferred by human immunodeficiency virus type 1 reverse transcriptase containing a diserine insertion after residue 69 and multiple thymidine analog-associated mutations. Kirsten L White, James M Chen, Nicolas A Margot, Terri Wrin, Christos J Petropoulos, Lisa K Naeger, S Swaminathan, Michael D Miller Antimicrob Agents Chemother 2004 topics set
Palm mutants in DNA polymerases alpha and eta alter DNA replication fidelity and translesion activity. Atsuko Niimi, Siripan Limsirichaikul, Shonen Yoshida, Shigenori Iwai, Chikahide Masutani, Fumio Hanaoka, Eric T Kool, Yoshitaka Nishiyama, Motoshi Suzuki Molecular and cellular biology 2004 pols set
Human DNA polymerases lambda and beta show different efficiencies of translesion DNA synthesis past abasic sites and alternative mechanisms for frameshift generation. Giuseppina Blanca, Giuseppe Villani, Igor V Shevelev, Kristijan Ramadan, Silvio Spadari, Ulrich Hübscher, Giovanni Maga Biochemistry 2004 pols set
Differential maintenance of the M184V substitution in the reverse transcriptase of human immunodeficiency virus type 1 by various nucleoside antiretroviral agents in tissue culture. Marco Petrella, Maureen Oliveira, Daniela D Moisi, Mervi Detorio, Bluma G Brenner, Mark A. Wainberg Antimicrobial agents and chemotherapy 2004 new
Investigating the effects of stereochemistry on incorporation and removal of 5-fluorocytidine analogs by mitochondrial DNA polymerase gamma: comparison of D- and L-D4FC-TP. Eisuke Murakami, Adrian S Ray, Raymond F Schinazi, Karen S Anderson Antiviral Res 2004 topics set
Influence of DNA structure on DNA polymerase beta active site function: extension of mutagenic DNA intermediates. William A Beard, David D Shock, Samuel H Wilson The Journal of biological chemistry 2004 topics set
Structural insights into DNA polymerase beta deterrents for misincorporation support an induced-fit mechanism for fidelity. Joseph M Krahn, William A Beard, Samuel H Wilson Structure (London, England : 1993) 2004 topics set
Polymerization of the triphosphates of AraC, 2',2'-difluorodeoxycytidine (dFdC) and OSI-7836 (T-araC) by human DNA polymerase alpha and DNA primase. Katherine A Richardson, Tanya P Vega, Frank C Richardson, Chad L Moore, John C Rohloff, Blake Tomkinson, Raymond A Bendele, Robert D Kuchta Biochem Pharmacol 2004 pols set
Inhibition of protein interactions with the beta 2 sliding clamp of Escherichia coli DNA polymerase III by peptides from beta 2-binding proteins. Gene Wijffels, Brian P Dalrymple, Pavel Prosselkov, Kritaya Kongsuwan, V Chandana Epa, Penelope E Lilley, Slobodan Jergic, Jens Buchardt, Susan E Brown, Paul F Alewood, Philip A Jennings, Nicholas E Dixon Biochemistry 2004 pols set
The Escherichia coli dnaN159 mutant displays altered DNA polymerase usage and chronic SOS induction. Mark D Sutton J Bacteriol 2004 new
Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. Gerald W Hsu, Matthias Ober, Thomas Carell, Lorena S Beese Nature 2004 topics set
Genotypic and phenotypic predictors of the magnitude of response to tenofovir disoproxil fumarate treatment in antiretroviral-experienced patients. Michael D Miller, Nicolas A Margot, Biao Lu, Lijie Zhong, Shan-Shan Chen, Andrew Cheng, Michael Wulfsohn J Infect Dis 2004 new
Structures of mismatch replication errors observed in a DNA polymerase. Sean J Johnson, Lorena S Beese Cell 2004 topics set
Evidence of finely tuned expression of DNA polymerase beta in vivo using transgenic mice. Valérie Bergoglio, Mathilde Fréchet, Magali Philippe, Anne Bieth, Pascale Mercier, Dominique Morello, Magali Lacroix-Tricki, Georges Delsol, Jean-Sébastien Hoffmann, Christophe Cazaux FEBS letters 2004 new
Noncompetitive counteractions of DNA polymerase epsilon and ISW2/yCHRAC for epigenetic inheritance of telomere position effect in Saccharomyces cerevisiae. Tetsushi Iida, Hiroyuki Araki Molecular and cellular biology 2004 new
The biochemical requirements of DNA polymerase V-mediated translesion synthesis revisited. Shingo Fujii, Véronique Gasser, Robert P P Fuchs Journal of molecular biology 2004 new
Crystal structures of HIV-1 reverse transcriptases mutated at codons 100, 106 and 108 and mechanisms of resistance to non-nucleoside inhibitors. Jingshan Ren, Charles E Nichols, Phillip P Chamberlain, Kurt L Weaver, Steven A Short, David K Stammers Journal of molecular biology 2004 partial results
The presence of 3'-5' exonuclease activity in rat brain neurons and its role in template-driven extension of 3'-mismatched primers by DNA-polymerase beta in aging neurons. T Hari Krishna, Anjana Hemkal, Kalluri Subba Rao Neurochem Res 2004 new
Insights into strand displacement and processivity from the crystal structure of the protein-primed DNA polymerase of bacteriophage phi29. Satwik Kamtekar, Andrea J Berman, Jianhong Wang, José María Lázaro, Miguel de Vega, Luis Blanco, Margarita Salas, Thomas A Steitz Molecular cell 2004 partial results
Antiviral drugs in current clinical use. Erik De Clercq J Clin Virol 2004 topics set
Dysfunctional proofreading in the Escherichia coli DNA polymerase III core. Duane A Lehtinen, Fred W Perrino Biochem J 2004 pols set
Twinkle and POLG defects enhance age-dependent accumulation of mutations in the control region of mtDNA. Sjoerd Wanrooij, Petri Luoma, Gert Van Goethem, Christine Van Broeckhoven, Anu Suomalainen, Johannes N Spelbrink Nucleic acids research 2004 pols set
In vitro bypass of malondialdehyde-deoxyguanosine adducts: differential base selection during extension by the Klenow fragment of DNA polymerase I is the critical determinant of replication outcome. Muhammed F Hashim, James N Riggins, Nathalie Schnetz-Boutaud, Markus W Voehler, Michael P Stone, Lawrence J Marnett Biochemistry 2004 pols set
Purification of Drosophila DNA polymerase zeta by REV1 protein-affinity chromatography. Ryo Takeuchi, Masahiko Oshige, Makiyo Uchida, Gen Ishikawa, Kei-ichi Takata, Kaori Shimanouchi, Yoshihiro Kanai, Tatsushi Ruike, Hiroshi Morioka, Kengo Sakaguchi Biochem J 2004 topics set
Cell cycle-dependent phosphorylation of the DNA polymerase epsilon subunit, Dpb2, by the Cdc28 cyclin-dependent protein kinase. Tapio Kesti, W Hayes McDonald, John R Yates, Curt Wittenberg The Journal of biological chemistry 2004 new
POLG mutations associated with Alpers' syndrome and mitochondrial DNA depletion. Robert K Naviaux, Khue V Nguyen Annals of neurology 2004 pols set
TMC125, a novel next-generation nonnucleoside reverse transcriptase inhibitor active against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus type 1. Koen Andries, Hilde Azijn, Theo Thielemans, Donald W Ludovici, Michael Kukla, Jan Heeres, Paul A J Janssen, Bart De Corte, Johan Vingerhoets, Rudi Pauwels, Marie-Pierre P De Béthune Antimicrob Agents Chemother 2004 complete
Mapping and mutation of the conserved DNA polymerase interaction motif (DPIM) located in the C-terminal domain of fission yeast DNA polymerase delta subunit Cdc27. Fiona C Gray, J Richard G Pohler, Emma Warbrick, Stuart A MacNeill BMC Mol Biol 2004 new
Primer utilization by DNA polymerase alpha-primase is influenced by its interaction with Mcm10p. Karen Fien, Young-Sik Cho, Joon-Kyu Lee, Santanu Raychaudhuri, Inger Tappin, Jerard Hurwitz The Journal of biological chemistry 2004 new
New lupane triterpenoids from Solidago canadensis that inhibit the lyase activity of DNA polymerase beta. V S Prakash Chaturvedula, Bing-Nan Zhou, Zhijie Gao, Shannon J Thomas, Sidney M Hecht, David G I Kingston Bioorg Med Chem 2004 new
Biscoumarin derivatives from Edgeworthia gardneri that inhibit the lyase activity of DNA polymerase beta. Shi-Sheng Li, Zhijie Gao, Xizhi Feng, Sidney M Hecht J Nat Prod 2004 new
Nonnucleoside HIV-1 reverse transcriptase inhibitors; part 3. Synthesis and antiviral activity of 5-alkyl-2-[(aryl and alkyloxyl-carbonylmethyl)thio]-6-(1-naphthylmethyl) pyrimidin-4(3H)-ones. Yanping He, Fener Chen, Xiongjie Yu, Yueping Wang, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Bioorganic chemistry 2004 pols set
Antitumor effect of a novel adeno-associated virus vector targeting to telomerase activity in tumor cells. Yi-Gang Wang, Jing-Houng Wang, Yan-Hong Zhang, Qing Gu, Xin-Yuan Liu Acta biochimica et biophysica Sinica 2004 new
Altering DNA polymerase incorporation fidelity by distorting the dNTP binding pocket with a bulky carcinogen-damaged template. S Frank Yan, Min Wu, Nicholas E Geacintov, Suse Broyde Biochemistry 2004 new
Structural and energetic characterization of nucleic acid-binding to the fingers domain of Moloney murine leukemia virus reverse transcriptase. Robert L Crowther, David P Remeta, Conceição A S A Minetti, Debanu Das, Sherwin P Montano, Millie M Georgiadis Proteins 2004 partial results
[Photoreactive dTTP analogues as substrates for thermostable DNA polymerase from Thermus thermophilus B35]. Natalia A Lebedeva, Nadejda I Rechkunova, Sergey V Dezhurov, S Kh Degtiarev, Olga I Lavrik Bioorg Khim 2004 new
Mechanism of loading the Escherichia coli DNA polymerase III sliding clamp: I. Two distinct activities for individual ATP sites in the gamma complex. Christopher R Williams, Anita K Snyder, Petr Kuzmic, Mike E O'Donnell, Linda B Bloom The Journal of biological chemistry 2004 pols set
Structural analysis of the inactive state of the Escherichia coli DNA polymerase clamp-loader complex. Steven L Kazmirski, Marjetka Podobnik, Tanya F Weitze, Mike E O'Donnell, John Kuriyan Proceedings of the National Academy of Sciences of the United States of America 2004 topics set
The activity of selected RB69 DNA polymerase mutants can be restored by manganese ions: the existence of alternative metal ion ligands used during the polymerization cycle. E Zakharova, Jianhong Wang, William H Konigsberg Biochemistry 2004 complete
The clinical significance of the POLG gene polymorphism in male infertility. C Krausz, E Guarducci, L Becherini, S Degl'Innocenti, L Gerace, G Balercia, G Forti The Journal of clinical endocrinology and metabolism 2004 new
Splice-site genetic polymorphism of the human kallikrein 12 (KLK12) gene correlates with no substantial expression of KLK12 protein having serine protease activity. Kazuya Shinmura, Hong Tao, Hidetaka Yamada, Hideki Kataoka, Ravshanov Sanjar, Jiandong Wang, Kimio Yoshimura, Haruhiko Sugimura Human mutation 2004 new
Nucleotide incorporation by human DNA polymerase gamma opposite benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyguanosine and deoxyadenosine. Maria A Graziewicz, Jane M Sayer, Donald M Jerina, William C Copeland Nucleic acids research 2004 pols set
The molecular perspective: DNA polymerase. David S Goodsell Stem Cells 2004 new
The effects of dehydroaltenusin, a novel mammalian DNA polymerase alpha inhibitor, on cell proliferation and cell cycle progression. Chikako Murakami-Nakai, Naoki Maeda, Yuko Yonezawa, Isoko Kuriyama, Shinji Kamisuki, Shunya Takahashi, Fumio Sugawara, Hiromi Yoshida, Kengo Sakaguchi, Yoshiyuki Mizushina Biochimica et biophysica acta 2004 pols set
Recognition of the pro-mutagenic base uracil by family B DNA polymerases from archaea. G Shuttleworth, M J Fogg, MR Kurpiewski, L Jen-Jacobson, Bernard A Connolly Journal of molecular biology 2004 topics set
Apurinic/apyrimidinic endonuclease (APE/REF-1) haploinsufficient mice display tissue-specific differences in DNA polymerase beta-dependent base excision repair. Julian J Raffoul, Diane C Cabelof, Jun Nakamura, Lisiane B Meira, Errol C Friedberg, Ahmad R Heydari The Journal of biological chemistry 2004 new
Correlations between factors determining the pharmacokinetics and antiviral activity of HIV-1 non-nucleoside reverse transcriptase inhibitors of the diaryltriazine and diarylpyrimidine classes of compounds. Paul J Lewi, Edward Arnold, Koen Andries, Hilde Bohets, Herman Borghys, Arthur D Clark, Frits F D Daeyaert, Kalyan Das, Marie-Pierre P De Béthune, Marc R De Jonge, Jan Heeres, Luc Koymans, Jos Leempoels, Jef Peeters, Philip Timmerman, Walter Van den Broeck, Frédéric Vanhoutte, Gerben Van't Klooster, Maarten H Vinkers, Yulia Volovik, Paul A J Janssen Drugs in R&D 2004 pols set
Activity of the isolated HIV RNase H domain and specific inhibition by N-hydroxyimides. Julie Qi Hang, Surendran Rajendran, Yanli Yang, Yingqian Li, Philippe Wong Kai In, Hilary Overton, Kevin E B Parkes, Nick Cammack, Joseph A Martin, Klaus Klumpp Biochem Biophys Res Commun 2004 pols set
Telomere attrition predominantly occurs in precursor lesions during in vivo carcinogenic process of the uterine cervix. Anju Zhang, Jianliu Wang, Biying Zheng, Xiaolei Fang, Tord Angström, Cheng Liu, Xincang Li, Fredrik Erlandsson, Magnus Björkholm, Magnus Nordenskjörd, Astrid Gruber, Keng-Ling Wallin, Dawei Xu Oncogene 2004 new
Development of single-domain recombinant antibodies to reverse transcriptase domain of human hTERT. Minyan Huang, Bo Zhang, Junmei Wang, Fang Mei, Lin Hou Hybridoma and hybridomics 2004 new
Conditionally replicative adenovirus driven by the human telomerase promoter provides broad-spectrum antitumor activity without liver toxicity. John Irving, Zhengqiang Wang, Sandra Powell, Chris O'Sullivan, Michael Mok, Brian Murphy, Lisa Cardoza, Jane S Lebkowski, Anish S Majumdar Cancer gene therapy 2004 new
Subunit interaction and regulation of activity through terminal domains of the family D DNA polymerase from Pyrococcus horikoshii. Yulong Shen, X-F Tang, Eriko Matsui, Ikuo Matsui Biochem Soc Trans 2004 pols set
Modulation of the 5'-deoxyribose-5-phosphate lyase and DNA synthesis activities of mammalian DNA polymerase beta by apurinic/apyrimidinic endonuclease 1. Donny Wong, Bruce Demple The Journal of biological chemistry 2004 pols set
Pre-steady-state kinetic studies of the fidelity of human DNA polymerase mu. Michelle P Roettger, Kevin A Fiala, Susmitha Sompalli, Yuxia Dong, Zucai Suo Biochemistry 2004 pols set
Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage. Patricia L Kannouche, Jonathan Wing, Alan R Lehmann Molecular cell 2004 pols set
In silico evidence for DNA polymerase-beta's substrate-induced conformational change. Karunesh Arora, Tamar Schlick Biophys J 2004 pols set
Very efficient template/primer-independent DNA synthesis by thermophilic DNA polymerase in the presence of a thermophilic restriction endonuclease. Xingguo Liang, Kari Jensen, Maxim D Frank-Kamenetskii Biochemistry 2004 new
Application of electrospray ionization mass spectrometry to study the hydrophobic interaction between the epsilon and theta subunits of DNA polymerase III. Rajesh Gupta, Samir M Hamdan, Nicholas E Dixon, Margaret M Sheil, Jennifer L Beck Protein science : a publication of the Protein Society 2004 pols set
[Antigenic and genetic characterizations of group A influenza viruses H3N2 circulated in men in China during 2000-2002]. Yongqing Zhang, Le-ying Wen, Zhongjie Li, Jun-Feng Guo, Min Wang, Yuan-ji Guo Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 2004 new
Plant sterols as selective DNA polymerase beta lyase inhibitors and potentiators of bleomycin cytotoxicity. Shi-Sheng Li, Zhijie Gao, Xizhi Feng, Shannon H Jones, Sidney M Hecht Bioorg Med Chem 2004 new
The human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase beta and increases its DNA substrate utilisation efficiency: implications for DNA repair. Magali Toueille, Nazim El-Andaloussi, Isabelle Frouin, Raimundo Freire, Dorothee Funk, Igor V Shevelev, Erica Friedrich-Heineken, Giuseppe Villani, Michael O Hottiger, Ulrich Hübscher Nucleic acids research 2004 new
POLG mutations in neurodegenerative disorders with ataxia but no muscle involvement. Gert Van Goethem, Petri Luoma, M Rantamäki, A Al Memar, Seppo Kaakkola, Peter Hackman, R Krahe, Ann Löfgren, Jean-Jacques Martin, P De Jonghe, Anu Suomalainen, Bjarne Udd, Christine Van Broeckhoven Neurology 2004 pols set
Design, synthesis, anti-HIV activities, and metabolic stabilities of alkenyldiarylmethane (ADAM) non-nucleoside reverse transcriptase inhibitors. Maximilian A Silvestri, Muthukaman Nagarajan, Erik De Clercq, Christophe Pannecouque, Mark Cushman Journal of medicinal chemistry 2004 pols set
De novo DNA synthesis by human DNA polymerase lambda, DNA polymerase mu and terminal deoxyribonucleotidyl transferase. Kristijan Ramadan, Igor V Shevelev, Giovanni Maga, Ulrich Hübscher Journal of molecular biology 2004 pols set
Distinct roles of DNA polymerases delta and epsilon at the replication fork in Xenopus egg extracts. Tomoyuki Fukui, Kazumi Yamauchi, Taketo Muroya, Masahiro Tatsumi Akiyama, Hisaji Maki, Akio Sugino, Shou Waga Genes Cells 2004 new
Site-specific mutagenesis of Drosophila proliferating cell nuclear antigen enhances its effects on calf thymus DNA polymerase delta. Dmitry Ju Mozzherin, Maeve McConnell, Holly Miller, Paul A Fisher BMC Biochem 2004 pols set
Differential gene expressions during immortalization of normal human fibroblasts and endothelial cells transfected with human telomerase reverse transcriptase gene. Tsutomu Kumazaki, Keiko Hiyama, Tomosaburo Takahashi, Hideaki Omatsu, Keiji Tanimoto, Takuya Noguchi, Eiso Hiyama, Youji Mitsui, Masahiko Nishiyama International journal of oncology 2004 new
Taking aim at a moving target: designing drugs to inhibit drug-resistant HIV-1 reverse transcriptases. Stefan G Sarafianos, Kalyan Das, Stephen H Hughes, Edward Arnold Current opinion in structural biology 2004 topics set
Novel inhibitors of HIV-1 integration. Myriam Witvrouw, Bénédicte Van Maele, J Vercammen, Anke Hantson, Y Engelborghs, Erik De Clercq, Christophe Pannecouque, Zeger Debyser Current drug metabolism 2004 pols set
High-level expression and purification of untagged and histidine-tagged HIV-1 reverse transcriptase. Esther W Hou, Rajendra Prasad, William A Beard, Samuel H Wilson Protein expression and purification 2004 pols set
Generic expansion of the substrate spectrum of a DNA polymerase by directed evolution. Farid J Ghadessy, Nicola Ramsay, François Boudsocq, David Loakes, Anthony Brown, Shigenori Iwai, Alexandra Vaisman, Roger Woodgate, Philipp Holliger Nat Biotechnol 2004 pols set
The DNA-polymerase-X family: controllers of DNA quality? Kristijan Ramadan, Igor V Shevelev, Ulrich Hübscher Nat Rev Mol Cell Biol 2004 new
Side-chain conformational restriction in template-competitive inhibitors of E. coli DNA polymerase I Klenow fragment: synthesis, structural characterization and inhibition activity. Michael B Doughty, Karam Aboudehen, Garland Anderson, Ke Li, Bob Moore, Tina Poolson Nucleosides, nucleotides & nucleic acids 2004 pols set
Design, efficient synthesis, and anti-HIV activity of 4'-C-cyano- and 4'-C-ethynyl-2'-deoxy purine nucleosides. Satoru Kohgo, Kohei Yamada, Kenji Kitano, Yuko Iwai, Shinji Sakata, Noriyuki Ashida, Hiroyuki Hayakawa, Daisuke Nameki, Eiichi N Kodama, Masao Matsuoka, Hiroyuki Mitsuya, Hiroshi Ohrui Nucleosides, nucleotides & nucleic acids 2004 new
HIV-1 reverse transcriptase inhibitors: current issues and future perspectives. Giada A Locatelli, Reynel Cancio, Silvio Spadari, Giovanni Maga Current drug metabolism 2004 pols set
Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis. Shuchismita Dutta, Yingqian Li, Donald E Johnson, Leonid Dzantiev, Charles C Richardson, Louis J Romano, Tom Ellenberger Proceedings of the National Academy of Sciences of the United States of America 2004 topics set
POLG mutations causing ophthalmoplegia, sensorimotor polyneuropathy, ataxia, and deafness. Michelangelo Mancuso, Massimiliano Filosto, M Bellan, R Liguori, P Montagna, A Baruzzi, Salvatore DiMauro, V Carelli Neurology 2004 pols set
Error-prone replication for better or worse. Brigette Tippin, Phuong Pham, Myron F Goodman Trends Microbiol 2004 pols set
Structural relationship of lithocholic acid derivatives binding to the N-terminal 8-kDa domain of DNA polymerase beta. Yoshiyuki Mizushina, Nobuyuki Kasai, Katsumi Miura, Shinya Hanashima, Masaharu Takemura, Hiromi Yoshida, Fumio Sugawara, Kengo Sakaguchi Biochemistry 2004 pols set
Increased hTR expression during transition from adenoma to carcinoma is not associated with promoter methylation. Atsuo Nakamura, Takeshi Suda, Terasu Honma, Tomosaburo Takahashi, Masato Igarashi, Nobuo Waguri, Hirokazu Kawai, Yusaku Mita, Yutaka Aoyagi Digestive diseases and sciences 2004 new
Dideoxynucleoside triphosphate-sensitive DNA polymerase from rice is involved in base excision repair and immunologically similar to mammalian DNA pol beta. Sailendra Nath Sarkar, Sankar Bakshi, Sanath K Mokkapati, Sujit Roy, Dibyendu Narayan SenGupta Biochem Biophys Res Commun 2004 new
Structural and biochemical analysis of sliding clamp/ligand interactions suggest a competition between replicative and translesion DNA polymerases. Dominique Y Burnouf, Vincent Olieric, Jérôme E Wagner, Shingo Fujii, J Reinbolt, Robert P P Fuchs, Philippe Dumas Journal of molecular biology 2004 complete Jérôme E Wagner*
Vif is an auxiliary factor of the HIV-1 reverse transcriptase and facilitates abasic site bypass. Reynel Cancio, Silvio Spadari, Giovanni Maga The Biochemical journal 2004 pols set
Co-localization in replication foci and interaction of human Y-family members, DNA polymerase pol eta and REVl protein. Agnès Tissier, Patricia L Kannouche, Marie-Pierre Reck, Alan R Lehmann, Robert P P Fuchs, Agnès Cordonnier DNA repair 2004 new
Modulation of hyperthermophilic DNA polymerase activity by archaeal chromatin proteins. Huiqiang Lou, Zhenhong Duan, Xiaofeng Huo, Li Huang The Journal of biological chemistry 2004 new
Persistence of multidrug-resistant HIV-1 in primary infection leading to superinfection. Bluma G Brenner, Jean-Pierre Routy, Yudong Quan, Daniela D Moisi, Maureen Oliveira, Dan Turner, Mark A. Wainberg AIDS (London, England) 2004 new
A novel polymerase gamma mutation in a family with ophthalmoplegia, neuropathy, and Parkinsonism. Michelangelo Mancuso, Massimiliano Filosto, Shin J Oh, Salvatore DiMauro Archives of neurology 2004 pols set
Petasiphenol which inhibits DNA polymerase lambda activity is an inhibitor of in vitro angiogenesis. Kiminori Matsubara, Masaharu Mori, Yoshiyuki Mizushina Oncol Rep 2004 new
Inhibition of HIV-1 reverse transcription: basic principles of drug action and resistance. Matthias Götte Expert Rev Anti Infect Ther 2004 topics set
Phage like it HOT: solution structure of the bacteriophage P1-encoded HOT protein, a homolog of the theta subunit of E. coli DNA polymerase III. Eugene F DeRose, Thomas W Kirby, Geoffrey A Mueller, Anna K Chikova, Roel M Schaaper, Robert E London Structure (London, England : 1993) 2004 pols set
Thermodynamic dissection of the polymerizing and editing modes of a DNA polymerase. Michael F Bailey, Edwin J C Van der Schans, David P Millar Journal of molecular biology 2004 pols set
Crystal structure of the catalytic core of human DNA polymerase kappa. Sacha N Uljon, Robert E Johnson, Thomas A Edwards, Satya Prakash, Louise Prakash, Aneel K Aggarwal Structure (London, England : 1993) 2004 pols set
Amplification of plant genomic DNA by Phi29 DNA polymerase for use in physical mapping of the hypermethylated genomic region. E Adachi, K Shimamura, S Wakamatsu, H Kodama Plant Cell Rep 2004 pols set
Increased dNTP binding affinity reveals a nonprocessive role for Escherichia coli beta clamp with DNA polymerase IV. Jeffrey G Bertram, Linda B Bloom, Mike E O'Donnell, Myron F Goodman The Journal of biological chemistry 2004 new
In vitro evaluation of nonnucleoside reverse transcriptase inhibitors UC-781 and TMC120-R147681 as human immunodeficiency virus microbicides. Yven Van Herrewege, Jo Michiels, Jens Van Roey, Katrien Fransen, Luc Kestens, Jan Balzarini, Paul J Lewi, Guido Vanham, Paul Janssen Antimicrobial agents and chemotherapy 2004 new
CADA, a novel CD4-targeted HIV inhibitor, is synergistic with various anti-HIV drugs in vitro. Kurt Vermeire, Katrien Princen, Sigrid Hatse, Erik De Clercq, Kaka Dey, Thomas W Bell, Dominique Schols AIDS (London, England) 2004 new
Unfaithful DNA polymerase caught in the act. Josef Jiricny Molecular cell 2004 new
Discovery and development of BVDU (brivudin) as a therapeutic for the treatment of herpes zoster. Erik De Clercq Biochemical pharmacology 2004 new
Susceptibility of feline immunodeficiency virus/human immunodeficiency virus type 1 reverse transcriptase chimeras to non-nucleoside RT inhibitors. Joeri Auwerx, Robert Esnouf, Erik De Clercq, Jan Balzarini Molecular pharmacology 2004 pols set
Nucleotide and amino acid polymorphisms at drug resistance sites in non-B-subtype variants of human immunodeficiency virus type 1. Dan Turner, Bluma G Brenner, Daniela D Moisi, Mervi Detorio, Raymond Cesaire, Takashi Kurimura, Haruyo Mori, Max Essex, Shlomo Maayan, Mark A. Wainberg Antimicrobial agents and chemotherapy 2004 pols set
High-efficiency bypass of DNA damage by human DNA polymerase Q. Masayuki Seki, Chikahide Masutani, Lee Wei Yang, Anthony Schuffert, Shigenori Iwai, Ivet Bahar, Richard D Wood The EMBO journal 2004 topics set
Cloning of a gene cluster responsible for the biosynthesis of diterpene aphidicolin, a specific inhibitor of DNA polymerase alpha. Tomonobu Toyomasu, Kentaro Nakaminami, Hiroaki Toshima, Takashi Mie, Kenji Watanabe, Hiroyuki Ito, Hirokazu Matsui, Wataru Mitsuhashi, Takeshi Sassa, Hideaki Oikawa Biosci Biotechnol Biochem 2004 new
Subunit protein-affinity isolation of Drosophila DNA polymerase catalytic subunit. Masahiko Oshige, Ryo Takeuchi, Tatsuji Ruike, Ryuji Ruike, Kazufumi Kuroda, Kengo Sakaguchi Protein Expr Purif 2004 partial results
Specific residues in the connector loop of the human cytomegalovirus DNA polymerase accessory protein UL44 are crucial for interaction with the UL54 catalytic subunit. Arianna Loregian, Brent A Appleton, James M Hogle, Donald M Coen J Virol 2004 complete Donald M Coen*
Strong positional preference in the interaction of LNA oligonucleotides with DNA polymerase and proofreading exonuclease activities: implications for genotyping assays. Daniel A Di Giusto, Garry C King Nucleic acids research 2004 new
Effects of drug resistance mutations L100I and V106A on the binding of pyrrolobenzoxazepinone nonnucleoside inhibitors to the human immunodeficiency virus type 1 reverse transcriptase catalytic complex. Giada A Locatelli, Giuseppe Campiani, Reynel Cancio, Elena Morelli, Anna Ramunno, Sandra Gemma, Ulrich Hübscher, Silvio Spadari, Giovanni Maga Antimicrobial agents and chemotherapy 2004 pols set
Site- and subunit-specific incorporation of unnatural amino acids into HIV-1 reverse transcriptase. George J Klarmann, Brian M Eisenhauer, Yongqing Zhang, Kalavathy Sitaraman, Deb K Chatterjee, Sidney M Hecht, Stuart F J Le Grice Protein expression and purification 2004 pols set
Domain topology of the DNA polymerase D complex from a hyperthermophilic archaeon Pyrococcus horikoshii. Xiao-Feng Tang, Yulong Shen, Eriko Matsui, Ikuo Matsui Biochemistry 2004 new
DNA replication fidelity. Thomas A Kunkel The Journal of biological chemistry 2004 topics set
Recognition of base-pairing by DNA polymerases during nucleotide incorporation: the properties of the mutagenic nucleotide dPTP alphaS. Victoria H Harris, Clifford L Smith, W Jonathan Cummins, Alan L Hamilton, David P Hornby, David M Williams Org Biomol Chem 2003 topics set
A conserved insertion in protein-primed DNA polymerases is involved in primer terminus stabilisation. Emmanuelle Dufour, Irene Rodríguez, José María Lázaro, Miguel de Vega, Margarita Salas Journal of molecular biology 2003 topics set
DNA polymerase III of Enterococcus faecalis: expression and characterization of recombinant enzymes encoded by the polC and dnaE genes. Kimberly A Foster, Marjorie H Barnes, Ryan O Stephenson, Michelle M Butler, Donna J Skow, William A LaMarr, Neal C Brown Protein Expr Purif 2003 new
Novel human immunodeficiency virus (HIV) inhibitors that have a dual mode of anti-HIV action. Miguel Stevens, Christophe Pannecouque, Erik De Clercq, Jan Balzarini Antimicrobial agents and chemotherapy 2003 pols set
A V106M mutation in HIV-1 clade C viruses exposed to efavirenz confers cross-resistance to non-nucleoside reverse transcriptase inhibitors. Bluma G Brenner, Dan Turner, Maureen Oliveira, Daniela D Moisi, Mervi Detorio, Mauricio Carobene, Richard G Marlink, Jonathan Schapiro, Michel Roger, Mark A. Wainberg AIDS (London, England) 2003 pols set
A peptide switch regulates DNA polymerase processivity. Francisco J López de Saro, Roxana E Georgescu, Mike E O'Donnell Proceedings of the National Academy of Sciences of the United States of America 2003 new
Taq DNA polymerase slippage mutation rates measured by PCR and quasi-likelihood analysis: (CA/GT)n and (A/T)n microsatellites. Deepali Shinde, Yinglei Lai, Fengzhu Sun, Norman Arnheim Nucleic acids research 2003 pols set
Lethality of bypass polymerases in Escherichia coli cells with a defective clamp loader complex of DNA polymerase III. Enrique Viguera, Mirjana Petranovic, Davor Zahradka, Karine Germain, Dusko S Ehrlich, Bénédicte Michel Molecular microbiology 2003 pols set
Fidelity mechanisms of DNA polymerase beta. Joann B Sweasy Prog Nucleic Acid Res Mol Biol 2003 new
The quaternary structure of DNA polymerase epsilon from Saccharomyces cerevisiae. Olga Chilkova, Bengt-Harald Jonsson, Erik Johansson The Journal of biological chemistry 2003 pols set
Utilization efficiency of the oxidized purine nucleotide analogs by DNA polymerase eta. Naomi Nishimoto, Hiroyuki Kamiya, Hideyoshi Harashima, Shunji Izuta Nucleic Acids Res Suppl 2003 new
Proliferating cell nuclear antigen (PCNA): a dancer with many partners. Giovanni Maga, Ulrich Hubscher Journal of cell science 2003 topics set
Comparative effects of adefovir and selected nucleoside inhibitors of hepatitis B virus DNA polymerase on mitochondrial DNA in liver and skeletal muscle cells. G Birkus, Craig S Gibbs, T Cihlar J Viral Hepat 2003 new
Detection of a new HIV-1 reverse transcriptase mutation (Q145M) conferring resistance to nucleoside and non-nucleoside inhibitors in a patient failing highly active antiretroviral therapy. Stefania Paolucci, Fausto Baldanti, Marco Tinelli, Giovanni Maga, Giuseppe Gerna AIDS (London, England) 2003 pols set
Nucleoside and nucleotide analogue reverse transcriptase inhibitors: a clinical review of antiretroviral resistance. Joel E Gallant, Peter Z Gerondelis, Mark A. Wainberg, Nancy S Shulman, Richard H Haubrich, Marty St Clair, Ernest R Lanier, Nicholas S Hellmann, Douglas D Richman Antivir Ther 2003 partial results
Nuclear magnetic resonance structures of the zinc finger domain of human DNA polymerase-alpha. Ferenc Evanics, Leila Maurmann, Wei Wen Yang, Rathindra N Bose Biochimica et biophysica acta 2003 topics set
DNA polymerase X of African swine fever virus: insertion fidelity on gapped DNA substrates and AP lyase activity support a role in base excision repair of viral DNA. Ramón García-Escudero, Miguel García-Díaz, María L Salas, Luis Blanco, José Salas Journal of molecular biology 2003 partial results
Modified DNA bearing 5(methoxycarbonylmethyl)-2'-deoxyuridine: preparation by PCR with thermophilic DNA polymerase and postsynthetic derivatization. Mohammad Mehedi Masud, Akiko Ozaki-Nakamura, Masayasu Kuwahara, Hiroaki Ozaki, Hiroaki Sawai Chembiochem 2003 new
The DNA polymerase alpha-primase complex: multiple functions and interactions. Marco Muzi-Falconi, Michele Giannattasio, Marco Foiani, Paolo Plevani ScientificWorldJournal 2003 new
Advantages of Thermococcus kodakaraenis (KOD) DNA Polymerase for PCR-mass spectrometry based analyses. Linda M Benson, Allison P Null, David C Muddiman J Am Soc Mass Spectrom 2003 pols set
Considering the cancer consequences of altered DNA polymerase function. Thomas A Kunkel Cancer Cell 2003 new
phi29 DNA polymerase residue Phe128 of the highly conserved (S/T)Lx(2)h motif is required for a stable and functional interaction with the terminal protein. Irene Rodríguez, José María Lázaro, Margarita Salas, Miguel de Vega Journal of molecular biology 2003 pols set
The frameshift infidelity of human DNA polymerase lambda. Implications for function. Katarzyna Bebenek, Miguel Garcia-Diaz, Luis Blanco, Thomas A Kunkel The Journal of biological chemistry 2003 partial results
Some anti-chronic inflammatory compounds are DNA polymerase lambda-specific inhibitors. Yoshiyuki Mizushina, Mitsuru Hirota, Chikako Murakami, Tomomi Ishidoh, Shinji Kamisuki, Noriko Shimazaki, Masaharu Takemura, Marinela Perpelescu, Motoshi Suzuki, Hiromi Yoshida, Fumio Sugawara, Osamu Koiwai, Kengo Sakaguchi Biochem Pharmacol 2003 new
Pyridoxal 5'-phosphate is a selective inhibitor in vivo of DNA polymerase alpha and epsilon. Yoshiyuki Mizushina, Xianai Xu, Kiminori Matsubara, Chikako Murakami, Isoko Kuriyama, Masahiko Oshige, Masaharu Takemura, Norihisa Kato, Hiromi Yoshida, Kengo Sakaguchi Biochem Biophys Res Commun 2003 new
Template-directed dye-terminator incorporation with fluorescence polarization detection for analysis of single nucleotide polymorphisms associated with cardiovascular and thromboembolic disease. Bradley D Freeman, Timothy G Buchman, Barbara A Zehnbauer Thromb Res 2003 topics set
DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1. Jennifer A Cobb, Lotte Bjergbaek, Kenji Shimada, Christian Frei, Susan M Gasser The EMBO journal 2003 new
Erroneous incorporation of oxidized DNA precursors by Y-family DNA polymerases. Masatomi Shimizu, Petr Gruz, Hiroyuki Kamiya, Su-Ryang Kim, Francesca M Pisani, Chikahide Masutani, Yusuke Kanke, Hideyoshi Harashima, Fumio Hanaoka, Takehiko Nohmi EMBO reports 2003 new
Molecular modeling calculations of HIV-1 reverse transcriptase nonnucleoside inhibitors: correlation of binding energy with biological activity for novel 2-aryl-substituted benzimidazole analogues. Marilyn B Kroeger Smith, Brian M Hose, Arie Hawkins, James Lipchock, David W Farnsworth, Robert C Rizzo, Julian Tirado-Rives, Edward Arnold, Weiming Zhang, Stephen H Hughes, William L Jorgensen, Christopher J Michejda, Richard H Smith Journal of medicinal chemistry 2003 pols set
Use of Pol I-deficient E. coli for functional complementation of DNA polymerase. Manel Camps, Lawrence A Loeb Methods in molecular biology (Clifton, N.J.) 2003 new
Error-prone DNA polymerase IV is controlled by the stress-response sigma factor, RpoS, in Escherichia coli. Jill C Layton, Patricia L Foster Molecular microbiology 2003 new
Clinical and genetic heterogeneity in progressive external ophthalmoplegia due to mutations in polymerase gamma. Massimiliano Filosto, Michelangelo Mancuso, Yutaka Nishigaki, Jacklyn Pancrudo, Yadollah Harati, Clifton Gooch, Ami Mankodi, Lydia Bayne, Eduardo Bonilla, Sara Shanske, Michio Hirano, Salvatore DiMauro Archives of neurology 2003 pols set
Computer simulation of the chemical catalysis of DNA polymerases: discriminating between alternative nucleotide insertion mechanisms for T7 DNA polymerase. Jan Florián, Myron F Goodman, Arieh Warshel Journal of the American Chemical Society 2003 new
Thermostable DNA-polymerase from the thermophilic archaeon microorganism Archaeoglobus fulgidus VC16 and its features. S E Chalov, O L Voronina, O N Sergienko, V G Lunin Biochemistry (Mosc) 2003 new
Drug resistance profiles of recombinant reverse transcriptases from human immunodeficiency virus type 1 subtypes A/E, B, and C. Yudong Quan, Bluma G Brenner, Richard G Marlink, Max Essex, Takashi Kurimura, Mark A. Wainberg AIDS research and human retroviruses 2003 new
Molecular impact of the M184V mutation in human immunodeficiency virus type 1 reverse transcriptase. Karidia Diallo, Matthias Götte, Mark A. Wainberg Antimicrobial agents and chemotherapy 2003 new
Synthesis and antiviral activity of some 5'-N-phthaloyl-3'-azido-2',3'-dideoxythymidine analogues. Jan Balzarini, Erik De Clercq, Beata Kaminska, Andrzej Orzeszko Antiviral chemistry & chemotherapy 2003 pols set
Nevirapine resistance mutation at codon 181 of the HIV-1 reverse transcriptase confers stavudine resistance by increasing nucleotide substrate discrimination and phosphorolytic activity. Giuseppina Blanca, Fausto Baldanti, Stefania Paolucci, Alexander Yu Skoblov, Lyubov Victorova, Ulrich Hübscher, Giuseppe Gerna, Silvio Spadari, Giovanni Maga The Journal of biological chemistry 2003 pols set
HIV-1 reverse transcriptase variants: molecular modeling of Y181C, V106A, L100I, and K103N mutations with nonnucleoside inhibitors using Monte Carlo simulations in combination with a linear response method. Marilyn B Kroeger Smith, Sandra Ruby, Stanislav Horouzhenko, Bryan Buckingham, Julia Richardson, Ina Puleri, Emily Potts, William L Jorgensen, Edward Arnold, Weiming Zhang, Stephen H Hughes, Christopher J Michejda, Richard H Smith Drug design and discovery 2003 pols set
Effects of 8-chlorodeoxyadenosine on DNA synthesis by the Klenow fragment of DNA polymerase I. Lisa S Chen, Michael H Bahr, Terry L Sheppard Bioorganic & medicinal chemistry letters 2003 pols set
Two-metal ion mechanism of RNA cleavage by HIV RNase H and mechanism-based design of selective HIV RNase H inhibitors. Klaus Klumpp, Julie Qi Hang, Surendran Rajendran, Yanli Yang, Andre Derosier, Philippe Wong Kai In, Hilary Overton, Kevin E B Parkes, Nick Cammack, Joseph A Martin Nucleic acids research 2003 pols set
Cadmium is a mutagen that acts by inhibiting mismatch repair. Yong Hwan Jin, Alan B Clark, Robbert J C Slebos, Hanan Al-Refai, Jack A Taylor, Thomas A Kunkel, Michael A Resnick, Dmitry A Gordenin Nature genetics 2003 new
Altered translesion synthesis in E. coli Pol V mutants selected for increased recombination inhibition. Suzanne Sommer, Olivier J Becherel, Geneviève Coste, Adriana Bailone, Robert P P Fuchs DNA repair 2003 topics set
8-Hydroxyguanine in a mutational hotspot of the c-Ha-ras gene causes misreplication, 'action-at-a-distance' mutagenesis and inhibition of replication. Paweł Jałoszyński, Chikahide Masutani, Fumio Hanaoka, Ana Blanco Perez, Susumu Nishimura Nucleic acids research 2003 new
Forty years of disinfectant failure: outbreak of postinjection Mycobacterium abscessus infection caused by contamination of benzalkonium chloride. Tejpratap S P Tiwari, Beverly Ray, Kenneth C Jost, Minaxi K Rathod, Yongqing Zhang, Barbara A Brown-Elliott, Kate Hendricks, Richard J Wallace Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003 new
Evaluating the effects of enhanced processivity and metal ions on translesion DNA replication catalyzed by the bacteriophage T4 DNA polymerase. Edmunds Z Reineks, Anthony J Berdis Journal of molecular biology 2003 pols set
Synthesis and antiviral activity of 1,3-disubstituted uracils against HIV-1 and HCMV. Tokumi Maruyama, Shigetada Kozai, Tetsuo Yamasaki, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoeck, Graciella Andrei, Erik De Clercq Antiviral chemistry & chemotherapy 2003 pols set
Novel POLG mutations in progressive external ophthalmoplegia mimicking mitochondrial neurogastrointestinal encephalomyopathy. Gert Van Goethem, Marianne Schwartz, Ann Löfgren, Bart Dermaut, Christine Van Broeckhoven, John Vissing European journal of human genetics : EJHG 2003 pols set
Structure-activity relationship studies on a novel family of specific HIV-1 reverse transcriptase inhibitors. María-Cruz Bonache, Cristina Chamorro, Esther Lobatón, Erik De Clercq, Jan Balzarini, Sonsoles Velázquez, María-José Camarasa, Ana San-Félix Antiviral chemistry & chemotherapy 2003 pols set
Evolutionary connection between the catalytic subunits of DNA-dependent RNA polymerases and eukaryotic RNA-dependent RNA polymerases and the origin of RNA polymerases. Lakshminarayan M Iyer, Eugene V Koonin, L Aravind BMC Struct Biol 2003 topics set
Synthesis, solution conformation and anti-HIV activity of novel 3'-substituted-2',3'-dideoxy-5-hydroxymethyluridines and their 4,5-substituted analogues. Jaroslaw Poznanski, Maria Bretner, Tadeusz Kulikowski, Jan Balzarini, Arthur Van Aerschot, Erik De Clercq Antiviral chemistry & chemotherapy 2003 pols set
Matrix-assisted laser desorption/ionization detection of polymerase chain reaction products by utilizing the 5'-3' exonuclease activity of Thermus aquaticus DNA polymerase. N R Isola, Z Liu, S L Allman, N I Taranenko, Y Kong, C H Chen Rapid Commun Mass Spectrom 2003 pols set
A conformationally locked analogue of the anti-HIV agent stavudine. An important correlation between pseudorotation and maximum amplitude. Yongseok Choi, Clifford George, Maria J Comin, Joseph J Barchi, Hak Sung Kim, Kenneth A Jacobson, Jan Balzarini, Hiroyuki Mitsuya, Paul L Boyer, Stephen H Hughes, Victor E Marquez Journal of medicinal chemistry 2003 pols set
DNA polymerase template interactions probed by degenerate isosteric nucleobase analogs. Natasha Paul, Vishal C Nashine, Geoffrey Hoops, Peiming Zhang, Jie Zhou, Donald E Bergstrom, V Jo Davisson Chemistry & biology 2003 topics set
Mitochondrial toxicity of NRTI antiviral drugs: an integrated cellular perspective. William Lewis, Brian J Day, William C Copeland Nature reviews. Drug discovery 2003 new
Structural determinants in human DNA polymerase gamma account for mitochondrial toxicity from nucleoside analogs. Susan E Lim, Mikhail V Ponamarev, Matthew J Longley, William C Copeland Journal of molecular biology 2003 pols set
Design, synthesis, SAR, and molecular modeling studies of acylthiocarbamates: a novel series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors structurally related to phenethylthiazolylthiourea derivatives. Angelo Ranise, Andrea Spallarossa, Silvia Schenone, Olga Bruno, Francesco Bondavalli, Laura Vargiu, Tiziana Marceddu, Massimo Mura, Paolo La Colla, Alessandra Pani Journal of medicinal chemistry 2003 pols set
Bridging PNAs can bind preferentially to a deleted mitochondrial DNA template but replication by mitochondrial DNA polymerase gamma in vitro is not impaired. Alistair McGregor, Paul M Smith, Günther F Ross, Robert W Taylor, Douglass M Turnbull, Robert N Lightowlers Biochimica et biophysica acta 2003 new
Facile polymerization of dNTPs bearing unnatural base analogues by DNA polymerase alpha and Klenow fragment (DNA polymerase I). Molly Chiaramonte, Chad L Moore, Kristi Kincaid, Robert D Kuchta Biochemistry 2003 topics set
Probing the mechanistic consequences of 5-fluorine substitution on cytidine nucleotide analogue incorporation by HIV-1 reverse transcriptase. Adrian S Ray, Raymond F Schinazi, Eisuke Murakami, Aravind Basavapathruni, Junxing Shi, Suzana M Zorca, Chung K Chu, Karen S Anderson Antivir Chem Chemother 2003 partial results
Effectiveness of rescue antiretroviral therapy including intravenously administered zidovudine and foscarnet in a child with HIV-1 enteropathy. Marc Hainaut, Michèle Gérard, Cécile Alexandra Peltier, Hichem Souayah, Françoise Mascart, Georges Zissis, Jack Levy Eur J Pediatr 2003 new
Deoxyribonucleoside 2'- or 3'-mixed disulfides: prodrugs to target ribonucleotide reductase and/or to inhibit HIV reverse transcription. Béatrice Roy, Stéphane Chambert, Michel Lepoivre, Anne-Marie Aubertin, Jan Balzarini, Jean-Luc Décout Journal of medicinal chemistry 2003 new
The application of a minicircle substrate in the study of the coordinated T4 DNA replication. Jingsong Yang, Michael A Trakselis, Rosa Maria Roccasecca, Stephen J Benkovic The Journal of biological chemistry 2003 topics set
DNA polymerase III chi subunit ties single-stranded DNA binding protein to the bacterial replication machinery. Gregor Witte, Claus Urbanke, Ute Curth Nucleic acids research 2003 new
POLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308. Federica Marini, Nayun Kim, Anthony Schuffert, Richard D Wood The Journal of biological chemistry 2003 new
Human DNA polymerase lambda diverged in evolution from DNA polymerase beta toward specific Mn(++) dependence: a kinetic and thermodynamic study. Giuseppina Blanca, Igor V Shevelev, Kristijan Ramadan, Giuseppe Villani, Silvio Spadari, Ulrich Hübscher, Giovanni Maga Biochemistry 2003 pols set
DNA polymerase gamma in mitochondrial DNA replication and repair. William C Copeland, Matthew J Longley ScientificWorldJournal 2003 new
Error-prone polymerase, DNA polymerase IV, is responsible for transient hypermutation during adaptive mutation in Escherichia coli. Joshua D Tompkins, Jennifer L Nelson, Jill C Hazel, Stacy L Leugers, Jeffrey D Stumpf, Patricia L Foster J Bacteriol 2003 topics set
Inhibition of human immunodeficiency virus by a new class of pyridine oxide derivatives. Miguel Stevens, Christophe Pannecouque, Erik De Clercq, Jan Balzarini Antimicrobial agents and chemotherapy 2003 pols set
Insertion of the T3 DNA polymerase thioredoxin binding domain enhances the processivity and fidelity of Taq DNA polymerase. John F Davidson, Richard Fox, Dawn D Harris, Sally Lyons-Abbott, Lawrence A Loeb Nucleic acids research 2003 partial results
Secondary structure in the nucleic acid affects the rate of HIV-1 nucleocapsid-mediated strand annealing. Marie-Pierre Golinelli, Stephen H Hughes Biochemistry 2003 pols set
Site-specific footprinting reveals differences in the translocation status of HIV-1 reverse transcriptase. Implications for polymerase translocation and drug resistance. Bruno Marchand, Matthias Götte The Journal of biological chemistry 2003 topics set
Subunit interaction and regulation of activity through terminal domains of the family D DNA polymerase from Pyrococcus horikoshii. Yulong Shen, Xiao-Feng Tang, Ikuo Matsui The Journal of biological chemistry 2003 pols set
Dendritic cells reconstituted with human telomerase gene induce potent cytotoxic T-cell response against different types of tumors. Maria Frolkis, Melissa B Fischer, Zhengqiang Wang, Jane S Lebkowski, Choy-Pik Chiu, Anish S Majumdar Cancer gene therapy 2003 new
Promoter analysis of the Chilo iridescent virus DNA polymerase and major capsid protein genes. Remziye Nalçacioğlu, Hendrik Marks, Just M Vlak, Zihni Demirbaĝ, Monique M van Oers Virology 2003 new
A sulphoquinovosyl diacylglycerol is a DNA polymerase epsilon inhibitor. Yoshiyuki Mizushina, Xianai Xu, Hitomi Asahara, Ryo Takeuchi, Masahiko Oshige, Noriko Shimazaki, Masaharu Takemura, Tsuyoshi Yamaguchi, Kazufumi Kuroda, Stuart Linn, Hiromi Yoshida, Osamu Koiwai, Mineo Saneyoshi, Fumio Sugawara, Kengo Sakaguchi Biochem J 2003 topics set
DNA polymerase epsilon - more than a polymerase. Helmut Pospiech, Juhani E Syväoja ScientificWorldJournal 2003 new
Recapitulation of the cellular xeroderma pigmentosum-variant phenotypes using short interfering RNA for DNA polymerase H. Rebecca R Laposa, Luzviminda Feeney, James E Cleaver Cancer research 2003 new
Potent and selective inhibition of HIV and SIV by prostratin interacting with viral entry. Myriam Witvrouw, Christophe Pannecouque, Valery Fikkert, Anke Hantson, Barbara Van Remoortel, Marjan Hezareh, Erik De Clercq, Stephen J Brown Antiviral chemistry & chemotherapy 2003 pols set
The absence of DNA polymerase kappa does not affect somatic hypermutation of the mouse immunoglobulin heavy chain gene. Takeyuki Shimizu, Yoichi Shinkai, Tomoo Ogi, Haruo Ohmori, Takachika Azuma Immunol Lett 2003 new
Ribozyme-mediated REV1 inhibition reduces the frequency of UV-induced mutations in the human HPRT gene. Denise R Clark, Wolfgang Zacharias, Luminita Panaitescu, William Glenn McGregor Nucleic acids research 2003 topics set
DNA polymerase beta can incorporate ribonucleotides during DNA synthesis of undamaged and CPD-damaged DNA. Valérie Bergoglio, Elena Ferrari, Ulrich Hübscher, Christophe Cazaux, Jean-Sébastien Hoffmann Journal of molecular biology 2003 new
Hypersensitivity of DNA polymerase beta null mouse fibroblasts reflects accumulation of cytotoxic repair intermediates from site-specific alkyl DNA lesions. Julie K Horton, Donna F Joyce-Gray, Brian F Pachkowski, James A Swenberg, Samuel H Wilson DNA repair 2003 new
Inhibition of human cytomegalovirus DNA polymerase by C-terminal peptides from the UL54 subunit. Arianna Loregian, Roberto Rigatti, Mary C Murphy, Elisabetta Schievano, Giorgio Palù, Howard S Marsden J Virol 2003 complete Arianna Loregian*
Negative effect of the M184V mutation in HIV-1 reverse transcriptase on initiation of viral DNA synthesis. Xin Wei, Chen Liang, Matthias Götte, Mark A. Wainberg Virology 2003 pols set
Identification of a novel protein, PDIP38, that interacts with the p50 subunit of DNA polymerase delta and proliferating cell nuclear antigen. Lingfeng Liu, Esther M Rodriguez-Belmonte, Nayef Mazloum, Bin Xie, Marietta Y W T Lee The Journal of biological chemistry 2003 pols set
Repair of damaged and mismatched DNA by the XPC homologues Rhp41 and Rhp42 of fission yeast. Thomas M Marti, Christophe Kunz, Oliver Fleck Genetics 2003 topics set
Presence of 18-A long hydrogen bond track in the active site of Escherichia coli DNA polymerase I (Klenow fragment). Its requirement in the stabilization of enzyme-template-primer complex. Kamalendra Singh, Mukund J Modak The Journal of biological chemistry 2003 pols set
Correlation of phenotypic zidovudine resistance with mutational patterns in the reverse transcriptase of human immunodeficiency virus type 1: interpretation of established mutations and characterization of new polymorphisms at codons 208, 211, and 214. Martin Stürmer, Schlomo Staszewski, Hans-Wilhelm Doerr, Brendan A Larder, Stuart Bloor, Kurt Hertogs Antimicrob Agents Chemother 2003 topics set
Diastereoselective formal total synthesis of the DNA polymerase alpha inhibitor, aphidicolin, using palladium-catalyzed cycloalkenylation and intramolecular Diels-Alder reactions. Masahiro Toyota, Masato Sasaki, Masataka Ihara Org Lett 2003 new
p21CDKN1A does not interfere with loading of PCNA at DNA replication sites, but inhibits subsequent binding of DNA polymerase delta at the G1/S phase transition. Ornella Cazzalini, Paola Perucca, Federica Riva, Lucia A Stivala, Livia Bianchi, Vanio Vannini, Bernard Ducommun, Ennio Prosperi Cell Cycle 2003 new
Lack of sugar discrimination by human Pol mu requires a single glycine residue. José F Ruiz, Raquel Juárez, Miguel García-Díaz, Gloria Terrados, Angel J Picher, Sergio González-Barrera, Antonio R Fernández de Henestrosa, Luis Blanco Nucleic acids research 2003 topics set
Structure of DNA polymerase beta with the mutagenic DNA lesion 8-oxodeoxyguanine reveals structural insights into its coding potential. Joseph M Krahn, William A Beard, Holly Miller, Arthur P Grollman, Samuel H Wilson Structure (London, England : 1993) 2003 topics set
Flavonoid glycoside: a new inhibitor of eukaryotic DNA polymerase alpha and a new carrier for inhibitor-affinity chromatography. Yoshiyuki Mizushina, Tomomi Ishidoh, Shinji Kamisuki, Satoshi Nakazawa, Masaharu Takemura, Fumio Sugawara, Hiromi Yoshida, Kengo Sakaguchi Biochem Biophys Res Commun 2003 new
Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells. Patricia L Kannouche, Antonio R Fernández de Henestrosa, Barry Coull, Antonio E Vidal, Colin Gray, Daniel Zicha, Roger Woodgate, Alan R Lehmann The EMBO journal 2003 new
Subunit interactions in the assembly of Saccharomyces cerevisiae DNA polymerase alpha. Subhasis B Biswas, Sujata M Khopde, Fan xiu Zhu Fx, Esther E Biswas Nucleic acids research 2003 pols set
Screening of DNA aptamers inhibiting Taq DNA polymerase using algorithm mimicking evolution. Kazunori Ikebukuro, Takahisa Noma Nucleic Acids Res Suppl 2003 pols set
Incorporation of reporter molecule-labeled nucleotides by DNA polymerases. II. High-density labeling of natural DNA. Taurai Tasara, Bernhard Angerer, Martine Damond, Holger Winter, Sabine Dörhöfer, Ulrich Hübscher, Mario Amacker Nucleic acids research 2003 new
Distinct function of conserved amino acids in the fingers of Saccharomyces cerevisiae DNA polymerase alpha. Masanori Ogawa, Siripan Limsirichaikul, Atsuko Niimi, Shigenori Iwai, Shonen Yoshida, Motoshi Suzuki The Journal of biological chemistry 2003 partial results
Structure-activity relationships in HIV-1 reverse transcriptase revealed by radiation target analysis. Nicolas Sluis-Cremer, Ellis Kempner, Michael A. Parniak Protein science : a publication of the Protein Society 2003 pols set
Mammalian translesion DNA synthesis across an acrolein-derived deoxyguanosine adduct. Participation of DNA polymerase eta in error-prone synthesis in human cells. In-Young Yang, Holly Miller, Zhengqiang Wang, Ekaterina G Frank, Haruo Ohmori, Fumio Hanaoka, Masaaki Moriya The Journal of biological chemistry 2003 new
Drug resistance patterns of recombinant herpes simplex virus DNA polymerase mutants generated with a set of overlapping cosmids and plasmids. Julie Bestman-Smith, Guy Boivin J Virol 2003 new
Selective inhibition of mammalian DNA polymerase alpha by vitamin D2 and D3. Yoshiyuki Mizushina, Xianai Xu, Chikako Murakami, Toshio Okano, Masaharu Takemura, Hiromi Yoshida, Kengo Sakaguchi J Pharmacol Sci 2003 pols set
Amino acid substitutions at position 190 of human immunodeficiency virus type 1 reverse transcriptase increase susceptibility to delavirdine and impair virus replication. Wei Huang, Andrea Gamarnik, Kay Limoli, Christos J Petropoulos, Jeannette M Whitcomb Journal of virology 2003 pols set
A fluorescence-based high-throughput screening assay for inhibitors of human immunodeficiency virus-1 reverse transcriptase-associated ribonuclease H activity. Michael A. Parniak, Kyung-Lyum Min, Scott R Budihas, Stuart F J Le Grice, John A Beutler Analytical biochemistry 2003 pols set
Tuning and switching a DNA polymerase motor with mechanical tension. Anita Goel, R Dean Astumian, Dudley Herschbach Proceedings of the National Academy of Sciences of the United States of America 2003 new
Competitive processivity-clamp usage by DNA polymerases during DNA replication and repair. Francisco J López de Saro, Roxana E Georgescu, Myron F Goodman, Mike E O'Donnell The EMBO journal 2003 new
Adenovirus type 5 DNA binding protein stimulates binding of DNA polymerase to the replication origin. Bas van Breukelen, Arjan B Brenkman, P Elly Holthuizen, Peter C van der Vliet J Virol 2003 new
Mutations in the 5' end of the human immunodeficiency virus type 1 polypurine tract affect RNase H cleavage specificity and virus titer. Mary Jane McWilliams, John G Julias, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes J Virol 2003 pols set
Decreased frequency and highly aberrant spectrum of ultraviolet-induced mutations in the hprt gene of mouse fibroblasts expressing antisense RNA to DNA polymerase zeta. Marilyn Diaz, Nicholas B Watson, Gene Turkington, Laurent K Verkoczy, Norman R Klinman, William Glenn McGregor Mol Cancer Res 2003 new
A new acylated oleanane triterpenoid from Couepia polyandra that inhibits the lyase activity of DNA polymerase beta. V S Prakash Chaturvedula, Zhijie Gao, Sidney M Hecht, Shannon H Jones, David G I Kingston J Nat Prod 2003 new
[Influenza activity in China from 2000 to 2001]. Yongqing Zhang, Zhongjie Li, Jun-Feng Guo, Min Wang, Le-ying Wen, Yuan-ji Guo Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 2003 new
Role of DNA polymerase eta in the UV mutation spectrum in human cells. Anne Stary, Patricia L Kannouche, Alan R Lehmann, Alain Sarasin The Journal of biological chemistry 2003 new
From RNA to quasispecies: a DNA polymerase with proofreading activity is highly recommended for accurate assessment of viral diversity. Isabelle Malet, Magali Belnard, Henri Agut, Annie Cahour J Virol Methods 2003 new
Probing the molecular mechanisms of AZT drug resistance mediated by HIV-1 reverse transcriptase using a transient kinetic analysis. Adrian S Ray, Eisuke Murakami, Aravind Basavapathruni, Joseph A Vaccaro, Dagny Ulrich, Chung K Chu, Raymond F Schinazi, Karen S Anderson Biochemistry 2003 topics set
Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates. Thomas A Kunkel, Youri I Pavlov, Katarzyna Bebenek DNA repair 2003 partial results
Multiplex single nucleotide extension: a robust and high throughput method for HLA-A locus typing. Mei Han, Yue Qing Tan, Yongqing Zhang, Jeannette Tsai, Rob Vorhaben, J Roberto Moraes, M Elisa Moraes, Peter Stastny Human immunology 2003 new
Interaction of DNA polymerase I (Klenow fragment) with the single-stranded template beyond the site of synthesis. Robert M Turner, Nigel D F Grindley, Catherine M Joyce Biochemistry 2003 pols set
[Effects of antisense oligodeoxynucleotides of human telomerase reverse transcriptase gene on telomerase activity in CEM cell line]. Wen-Yu Li, Yongqing Zhang, Dong-Mei He Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology 2003 new
Mutagenesis of benzo[a]pyrene diol epoxide in yeast: requirement for DNA polymerase zeta and involvement of DNA polymerase eta. Zhongwen Xie, Elena K Braithwaite, Dongyu Guo, Bo Zhao, Nicholas E Geacintov, Zhengqiang Wang Biochemistry 2003 new
Hold tight (but not too tight) to get it right: accurate bypass of an 8-oxoguanine lesion by DNA polymerase beta. Luis G Brieba, Tom Ellenberger Structure (London, England : 1993) 2003 topics set
Mutations E44D and V118I in the reverse transcriptase of HIV-1 play distinct mechanistic roles in dual resistance to AZT and 3TC. Mélanie Girouard, Karidia Diallo, Bruno Marchand, Suzanne McCormick, Matthias Götte The Journal of biological chemistry 2003 topics set
[Comparative study of the efficacy of modifying DNA polymerase and DNA matrix by different photoactive groups at the 3'-end of the DNA primer]. Sergey V Dezhurov, Svetlana N Khodyreva, Nadejda I Rechkunova, Dmitry M Kolpashchikov, Olga I Lavrik Bioorg Khim 2003 pols set
Multiple effects of the M184V resistance mutation in the reverse transcriptase of human immunodeficiency virus type 1. Dan Turner, Bluma G Brenner, Mark A. Wainberg Clinical and diagnostic laboratory immunology 2003 new
Mutations of ANT1, Twinkle, and POLG1 in sporadic progressive external ophthalmoplegia (PEO). A Agostino, L Valletta, Patrick F Chinnery, Gianfrancesco Ferrari, Franco Carrara, Robert W Taylor, Andrew M Schaefer, Douglass M Turnbull, Valeria Tiranti, Massimo Zeviani Neurology 2003 pols set
Constitutive and regulated expression of the mouse Dinb (Polkappa) gene encoding DNA polymerase kappa. Susana Velasco-Miguel, James A Richardson, Valerie L Gerlach, Wayne C Lai, Tianshu Gao, Lonnie D Russell, Christa L Hladik, Charles L White, Errol C Friedberg DNA repair 2003 new
Activation of human telomerase reverse transcriptase expression by some new symmetrical bis-substituted derivatives of the anthraquinone. Hsu-Shan Huang, Jeng-Fong Chiou, Yaou Fong, Ching-Cheng Hou, Yu-Cheng Lu, Jen-Yi Wang, Jing-Wen Shih, Yen-Ru Pan, Jing-Jer Lin Journal of medicinal chemistry 2003 new
Cut5 is required for the binding of Atr and DNA polymerase alpha to genotoxin-damaged chromatin. Edgardo R Parrilla-Castellar, Larry M Karnitz The Journal of biological chemistry 2003 new
N-aminoimidazole derivatives inhibiting retroviral replication via a yet unidentified mode of action. Irene M Lagoja, Christophe Pannecouque, Arthur Van Aerschot, Myriam Witvrouw, Zeger Debyser, Jan Balzarini, Piet Herdewijn, Erik De Clercq Journal of medicinal chemistry 2003 pols set
The mechanism of nucleotide incorporation by human DNA polymerase eta differs from that of the yeast enzyme. M Todd Washington, Robert E Johnson, Louise Prakash, Satya Prakash Molecular and cellular biology 2003 topics set
Characterization of the catalytic subunit of the human herpesvirus 6 (HHV-6) DNA polymerase expressed in an in vitro transcription/translation assay. Leen De Bolle, Jan Balzarini, Erik De Clercq, Lieve Naesens Nucleosides, nucleotides & nucleic acids 2003 new
A new binary system for photosensitized labeling of DNA polymerases in nuclear extract. Natalia A Lebedeva, Nadejda I Rechkunova, Sergey V Dezhurov, Svetlana N Khodyreva, Alain Favre, Olga I Lavrik Biochemistry. Biokhimii͡a 2003 new
Intermolecular ion pairs maintain the toroidal structure of Pyrococcus furiosus PCNA. Shigeki Matsumiya, Sonoko Ishino, Yoshizumi Ishino, Kosuke Morikawa Protein science : a publication of the Protein Society 2003 new
Chromosomal replicases as asymmetric dimers: studies of subunit arrangement and functional consequences. Charles S McHenry Molecular microbiology 2003 pols set
Escherichia coli DNA polymerase V subunit exchange: a post-SOS mechanism to curtail error-prone DNA synthesis. Xuan Shen, Roger Woodgate, Myron F Goodman The Journal of biological chemistry 2003 pols set
Unique error signature of the four-subunit yeast DNA polymerase epsilon. Polina V Shcherbakova, Youri I Pavlov, Olga Chilkova, Igor B Rogozin, Erik Johansson, Thomas A Kunkel The Journal of biological chemistry 2003 pols set
Patient homozygous for a recessive POLG mutation presents with features of MERRF. Gert Van Goethem, R Mercelis, Ann Löfgren, Sara Seneca, C Ceuterick, Jean-Jacques Martin, Christine Van Broeckhoven Neurology 2003 pols set
Computer simulation studies of the fidelity of DNA polymerases. Jan Florián, Myron F Goodman, Arieh Warshel Biopolymers 2003 new
Deoxynucleotide triphosphate binding mode conserved in Y family DNA polymerases. Robert E Johnson, José Trincao, Aneel K Aggarwal, Satya Prakash, Louise Prakash Molecular and cellular biology 2003 topics set
Site-directed mutagenesis analysis of the structural interaction of the single-strand-break repair protein, X-ray cross-complementing group 1, with DNA polymerase beta. Assen Marintchev, Michael R Gryk, Gregory P Mullen Nucleic acids research 2003 new
Comparison of checkpoint responses triggered by DNA polymerase inhibition versus DNA damaging agents. Jen-Sing Liu, Shu-Ru Kuo, Thomas Melendy Mutation research 2003 new
Suppressed catalytic activity of base excision repair enzymes on rotationally positioned uracil in nucleosomes. Brian C Beard, Samuel H Wilson, Michael J Smerdon Proceedings of the National Academy of Sciences of the United States of America 2003 complete Michael J Smerdon*
Structural basis for recruitment of translesion DNA polymerase Pol IV/DinB to the beta-clamp. Karen A Bunting, S Mark Roe, Laurence H Pearl The EMBO journal 2003 topics set
A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity. Julie K Pfeiffer, Karla Kirkegaard Proceedings of the National Academy of Sciences of the United States of America 2003 topics set
Toxicity of nucleoside analogues used to treat AIDS and the selectivity of the mitochondrial DNA polymerase. Harold R Lee, Jeremiah Hanes, Kenneth A Johnson Biochemistry 2003 new
The inhibitory action of pyrrolidine alkaloid, 1,4-dideoxy-1,4-imino-D-ribitol, on eukaryotic DNA polymerases. Yoshiyuki Mizushina, Xianai Xu, Naoki Asano, Nobuyuki Kasai, Atsushi Kato, Masaharu Takemura, Hitomi Asahara, Stuart Linn, Fumio Sugawara, Hiromi Yoshida, Kengo Sakaguchi Biochemical and biophysical research communications 2003 new
[Effect of human telomerase reverse transcriptase mRNA introduction on the growth of human umbilicus vein endothelial cell]. Yi Qu, Zheng-rong Wang, Xiang Huang Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 2003 new
DNA polymerase-mediated DNA synthesis on a TNA template. John C Chaput, Justin K Ichida, Jack W Szostak Journal of the American Chemical Society 2003 new
Selection of novel eukaryotic DNA polymerases by mutagenesis and genetic complementation of yeast. Ranga N Venkatesan, Lawrence A Loeb Methods in molecular biology (Clifton, N.J.) 2003 new
Effect of novel benzoylphenylurea derivatives on DNA polymerase alpha activity using the synthesome-based in vitro model system. Waleed Abdel-Aziz, Robert J Hickey, Martin Edelman, Linda H Malkas Invest New Drugs 2003 new
Differential mutation patterns in thymidine kinase and DNA polymerase genes of herpes simplex virus type 1 clones passaged in the presence of acyclovir or penciclovir. Tatsuo Suzutani, Ken Ishioka, Erik De Clercq, Kei Ishibashi, Hisatoshi Kaneko, Toshihiko Kira, Koh-Ichi Hashimoto, Masahiro Ogasawara, Katsuki Ohtani, Nobutaka Wakamiya, Masayuki Saijo Antimicrobial agents and chemotherapy 2003 new
Recessive POLG mutations presenting with sensory and ataxic neuropathy in compound heterozygote patients with progressive external ophthalmoplegia. Gert Van Goethem, Jean-Jacques Martin, Bart Dermaut, Ann Löfgren, A Wibail, D Ververken, P Tack, I Dehaene, M Van Zandijcke, M Moonen, C Ceuterick, P De Jonghe, Christine Van Broeckhoven Neuromuscular disorders : NMD 2003 pols set
Molecular model of SARS coronavirus polymerase: implications for biochemical functions and drug design. Xiang Xu, Yunqing Liu, Susan Weiss, Edward Arnold, Stefan G Sarafianos, Jianping Ding Nucleic acids research 2003 new
Hypoxia-induced modification of poly (ADP-ribose) polymerase and dna polymerase beta activity in cerebral cortical nuclei of newborn piglets: role of nitric oxide. O P Mishra, W Akhter, Q M Ashraf, M Delivoria-Papadopoulos Neuroscience 2003 new
Effect of the oxidized guanosine lesions spiroiminodihydantoin and guanidinohydantoin on proofreading by Escherichia coli DNA polymerase I (Klenow fragment) in different sequence contexts. Olga Kornyushyna, Cynthia J Burrows Biochemistry 2003 pols set
Are there mutator polymerases? Miguel García-Díaz, José F Ruiz, Raquel Juárez, Gloria Terrados, Luis Blanco ScientificWorldJournal 2003 topics set
Targeted gene evolution in Escherichia coli using a highly error-prone DNA polymerase I. Manel Camps, Jussi Naukkarinen, Ben P Johnson, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 2003 new
[Preliminary analysis on human telomerase reverse transcriptase gene expression in acute leukemia]. Yongqing Zhang, Shu-qiu Liu, Yi Qu, Xi-hong Li, Feng-lan Wang, Wei Dong, Bai-lin Liu Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 2003 new
Analysis of translesion replication across an abasic site by DNA polymerase IV of Escherichia coli. Ayelet Maor-Shoshani, Kiyoshi Hayashi, Haruo Ohmori, Zvi Livneh DNA repair 2003 pols set
[Hepatitis B virus genotypes and the heterogeneity of its polymerase gene]. Guo-bing Zeng, Shu-juan Wen, Jian Sun, Ze-yan Guo, Zhan-hui Wang, Kang-xian Luo, Li Yan, Jin-lin Hou Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 2003 new
Sequence context-dependent replication of DNA templates containing UV-induced lesions by human DNA polymerase iota. Alexandra Vaisman, Ekaterina G Frank, Shigenori Iwai, Eiji Ohashi, Haruo Ohmori, Fumio Hanaoka, Roger Woodgate DNA repair 2003 pols set
Polymerase mu is a DNA-directed DNA/RNA polymerase. Stephanie A Nick McElhinny, Dale A Ramsden Molecular and cellular biology 2003 topics set
[Expression of human telomerase reverse transcriptase and bcl-2 in ameloblastoma]. Jie Wang, Ming Zhong, Zhengqiang Wang Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 2003 new
Flexibility revealed by the 1.85 A crystal structure of the beta sliding-clamp subunit of Escherichia coli DNA polymerase III. Aaron J Oakley, Pavel Prosselkov, Gene Wijffels, Jennifer L Beck, Matthew C J Wilce, Nicholas E Dixon Acta Crystallogr D Biol Crystallogr 2003 topics set
Yeast DNA polymerase eta makes functional contacts with the DNA minor groove only at the incoming nucleoside triphosphate. M Todd Washington, William T Wolfle, Thomas E Spratt, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2003 topics set
A novel genetic pathway of human immunodeficiency virus type 1 resistance to stavudine mediated by the K65R mutation. J Gerardo García-Lerma, Hamish MacInnes, Diane Bennett, Patrick Reid, Soumya Nidtha, Hillard Weinstock, Jonathan E Kaplan, Walid Heneine Journal of virology 2003 pols set
Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations. Sean J Johnson, Jeffrey S Taylor, Lorena S Beese Proceedings of the National Academy of Sciences of the United States of America 2003 partial results
Mutagenesis of human DNA polymerase lambda: essential roles of Tyr505 and Phe506 for both DNA polymerase and terminal transferase activities. Igor V Shevelev, Giuseppina Blanca, Giuseppe Villani, Kristijan Ramadan, Silvio Spadari, Ulrich Hübscher, Giovanni Maga Nucleic acids research 2003 pols set
Telomerase activity and cell apoptosis in colon cancer cell by human telomerase reverse transcriptase gene antisense oligodeoxynucleotide. Ying-An Jiang, He-Sheng Luo, You-Yuan Zhang, Li-Fang Fan, Chong-Qing Jiang, Wei-Jin Chen World journal of gastroenterology : WJG 2003 new
Differences in replication of a DNA template containing an ethyl phosphotriester by T4 DNA polymerase and Escherichia coli DNA polymerase I. Laura Tsujikawa, Michael Weinfield, Linda J Reha-Krantz Nucleic acids research 2003 complete
Development of a cell-based enzyme-linked immunosorbent assay for high-throughput screening of HIV type 1 entry inhibitors targeting the coreceptor CXCR4. Qian Zhao, Hong Lu, Dominique Schols, Erik De Clercq, Shibo Jiang AIDS research and human retroviruses 2003 pols set
Therapy and short-term prophylaxis of poxvirus infections: historical background and perspectives. Johan Neyts, Erik De Clercq Antiviral research 2003 new
Molecular cloning of the canine telomerase reverse transcriptase gene and its expression in neoplastic and non-neoplastic cells. Mitsuhiro Yazawa, Masaru Okuda, Noriko Kanaya, Sung-Hyeok Hong, Tomosaburo Takahashi, Emi Ohashi, Takayuki Nakagawa, Ryohei Nishimura, Nobuo Sasaki, Kenichi Masuda, Koichi Ohno, Hajime Tsujimoto American journal of veterinary research 2003 new
Polyelectrolyte surface interface for single-molecule fluorescence studies of DNA polymerase. Emil P Kartalov, Marc A Unger, Stephen R Quake BioTechniques 2003 new
Replication of a cis-syn thymine dimer at atomic resolution. Hong Ling, François Boudsocq, Brian S Plosky, Roger Woodgate, Wei Wen Yang Nature 2003 topics set
Trypanosoma brucei has two distinct mitochondrial DNA polymerase beta enzymes. Tina T Saxowsky, Gunjan Choudhary, Michele M Klingbeil, Paul T Englund The Journal of biological chemistry 2003 new
Nucleotide excision repair- and polymerase eta-mediated error-prone removal of mitomycin C interstrand cross-links. Huyong Zheng, Xin Wang, Amy J Warren, Randy J Legerski, Rodney S Nairn, Joshua W Hamilton, Lei Li Molecular and cellular biology 2003 new
Evolutionary clues to DNA polymerase III beta clamp structural mechanisms. Andrew F Neuwald Nucleic acids research 2003 new
Remarkable infidelity of polymerase gammaA associated with mutations in POLG1 exonuclease domain. Roberto Del Bo, Andreina Bordoni, M Sciacco, Alessio Di Fonzo, S Galbiati, Marco Crimi, Nereo Bresolin, Giacomo P Comi Neurology 2003 pols set
Inhibitory action of emulsified sulfoquinovosyl acylglycerol on mammalian DNA polymerases. Yoshiyuki Mizushina, Naoki Maeda, Miho Kawasaki, Hideki Ichikawa, Chikako Murakami, Masaharu Takemura, Xianai Xu, Fumio Sugawara, Yoshinobu Fukumori, Hiromi Yoshida, Kengo Sakaguchi Lipids 2003 new
Inhibition of HIV-1 ribonuclease H by a novel diketo acid, 4-[5-(benzoylamino)thien-2-yl]-2,4-dioxobutanoic acid. Cathryn A Shaw-Reid, Vandna Munshi, Pia Graham, Abigail Wolfe, Marc Witmer, Renee Danzeisen, David B Olsen, Steven S Carroll, Mark Embrey, John S Wai, Michael D Miller, James L Cole, Daria J Hazuda The Journal of biological chemistry 2003 new
The M184V substitution in human immunodeficiency virus type 1 reverse transcriptase delays the development of resistance to amprenavir and efavirenz in subtype B and C clinical isolates. Karidia Diallo, Bluma G Brenner, Maureen Oliveira, Daniela D Moisi, Mervi Detorio, Matthias Götte, Mark A. Wainberg Antimicrobial agents and chemotherapy 2003 pols set
Identification and characterization of an intermediate in the alkali degradation of (6-4) photoproduct-containing DNA. Miho Higurashi, Takashi Ohtsuki, Aki Inase, Rika Kusumoto, Chikahide Masutani, Fumio Hanaoka, Shigenori Iwai The Journal of biological chemistry 2003 new
Immunoglobulin kappa light chain gene rearrangement is impaired in mice deficient for DNA polymerase mu. Barbara Bertocci, Annie De Smet, Claudia Berek, Jean-Claude Weill, Claude-Agnès Reynaud Immunity 2003 new
Staying straight with A-tracts: a DNA analog of the HIV-1 polypurine tract. Marie L Coté, Mark Pflomm, Millie M Georgiadis Journal of molecular biology 2003 new
Lamivudine can exert a modest antiviral effect against human immunodeficiency virus type 1 containing the M184V mutation. Yudong Quan, Bluma G Brenner, Maureen Oliveira, Mark A. Wainberg Antimicrobial agents and chemotherapy 2003 pols set
Yeast DNA polymerase zeta (zeta) is essential for error-free replication past thymine glycol. Robert E Johnson, Sung-Lim Yu, Satya Prakash, Louise Prakash Genes & development 2003 new
Protein-protein interactions in the bacteriophage T4 replisome. The leading strand holoenzyme is physically linked to the lagging strand holoenzyme and the primosome. Faoud T Ishmael, Michael A Trakselis, Stephen J Benkovic The Journal of biological chemistry 2003 topics set
The efficiency and specificity of apurinic/apyrimidinic site bypass by human DNA polymerase eta and Sulfolobus solfataricus Dpo4. Robert J Kokoska, Scott D McCulloch, Thomas A Kunkel The Journal of biological chemistry 2003 topics set
Analysis of cell cycle regulation by 1-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride (SQMG), an inhibitor of eukaryotic DNA polymerases. Chikako Murakami, Masaharu Takemura, Hiromi Yoshida, Fumio Sugawara, Kengo Sakaguchi, Yoshiyuki Mizushina Biochemical pharmacology 2003 new
Anti-HIV agents: design and discovery of new potent RT inhibitors. Maria Letizia Barreca, Alba Chimirri, Erik De Clercq, Laura De Luca, Anna-Maria Monforte, Pietro Monforte, Angela Rao, Maria Zappalà Farmaco (Società chimica italiana : 1989) 2003 pols set
Relationship between 3'-azido-3'-deoxythymidine resistance and primer unblocking activity in foscarnet-resistant mutants of human immunodeficiency virus type 1 reverse transcriptase. Peter R Meyer, Suzanne E Matsuura, Dianna Zonarich, Rahul R Chopra, Eric Pendarvis, Holly Z Bazmi, John W Mellors, Walter A Scott J Virol 2003 complete Walter A Scott*
Crystal structure of the Pyrococcus horikoshii DNA primase-UTP complex: implications for the mechanism of primer synthesis. Nobutoshi Ito, Osamu Nureki, Mikako Shirouzu, Shigeyuki Yokoyama, Fumio Hanaoka Genes to cells : devoted to molecular & cellular mechanisms 2003 new
A novel DNA polymerase inhibitor and a potent apoptosis inducer: 2-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride with stearic acid. Chikako Murakami, Takayuki Yamazaki, Shinya Hanashima, Shunya Takahashi, Masaharu Takemura, Shonen Yoshida, Keisuke Ohta, Hiromi Yoshida, Fumio Sugawara, Kengo Sakaguchi, Yoshiyuki Mizushina Biochimica et biophysica acta 2003 new
Enhanced suicide gene therapy by chimeric tumor-specific promoter based on HSF1 transcriptional regulation. Jinhui Wang, Mingzhong Yao, Zhenzhong Zhang, Jinfa Gu, Yongqing Zhang, Binhua Li, Lanying Sun, Xinyuan Liu FEBS letters 2003 new
Requirement of Watson-Crick hydrogen bonding for DNA synthesis by yeast DNA polymerase eta. M Todd Washington, Sandra A Helquist, Eric T Kool, Louise Prakash, Satya Prakash Molecular and cellular biology 2003 topics set
Amino acid substitutions at conserved tyrosine 52 alter fidelity and bypass efficiency of human DNA polymerase eta. Eitan Glick, Janice S Chau, Kellie L Vigna, Scott D McCulloch, Elinor T Adman, Thomas A Kunkel, Lawrence A Loeb The Journal of biological chemistry 2003 partial results
Inhibition of DNA polymerases and DNA topoisomerase II by triterpenes produced by plant callus. Yoshiyuki Mizushina, Akira Ikuta, Kenji Endoh, Masahiko Oshige, Nobuyuki Kasai, Kohei Kamiya, Toshiko Satake, Hiroshi Takazawa, Hiromasa Morita, Hiroaki Tomiyasu, Hiromi Yoshida, Fumio Sugawara, Kengo Sakaguchi Biochemical and biophysical research communications 2003 new
Roles of Saccharomyces cerevisiae DNA polymerases Poleta and Polzeta in response to irradiation by simulated sunlight. Stanislav G Kozmin, Youri I Pavlov, Thomas A Kunkel, Evelyne Sage Nucleic acids research 2003 pols set
Mutations in DNA polymerase gamma cause error prone DNA synthesis in human mitochondrial disorders. William C Copeland, Mikhail V Ponamarev, Dinh Nguyen, Thomas A Kunkel, Matthew J Longley Acta Biochim Pol 2003 new
Characterization of novel reverse transcriptase and other RNA-associated catalytic activities by human DNA polymerase gamma: importance in mitochondrial DNA replication. Eisuke Murakami, Joy Y Feng, Harold R Lee, Jeremiah Hanes, Kenneth A Johnson, Karen S Anderson The Journal of biological chemistry 2003 pols set
Cladistic analysis of iridoviruses based on protein and DNA sequences. J W Wang, R Q Deng, X Z Wang, Y S Huang, K Xing, J H Feng, J G He, Q X Long Archives of virology 2003 new
Novel pyrazolo[3,4-d]pyrimidine-based inhibitors of Staphlococcus aureus DNA polymerase III: design, synthesis, and biological evaluation. Amjad Ali, Gayle E Taylor, Ken Ellsworth, Georgianna Harris, Ronald Painter, Lynn L Silver, Katherine Young J Med Chem 2003 new
Herpes simplex virus type-1: a model for genome transactions. Paul E Boehmer, Giuseppe Villani Progress in nucleic acid research and molecular biology 2003 new
A three dimensional (3-D) physical model of DNA polymerase movement in DNA replication. Kang Cheng, Chang Hua Zou Biomed Sci Instrum 2003 new
Apoptosis in cumulus cells during in vitro maturation of bovine cumulus-enclosed oocytes. S Ikeda, H Imai, M Yamada Reproduction (Cambridge, England) 2003 pols set
Genetic cooperation between the Werner syndrome protein and poly(ADP-ribose) polymerase-1 in preventing chromatid breaks, complex chromosomal rearrangements, and cancer in mice. Michel Lebel, Josée Lavoie, Isabelle Gaudreault, Marc Bronsard, Régen Drouin Am J Pathol 2003 new
Effects of glycolipids from spinach on mammalian DNA polymerases. Chikako Murakami, Taeko Kumagai, Takahiko Hada, Ui Kanekazu, Satoshi Nakazawa, Shinji Kamisuki, Naoki Maeda, Xianai Xu, Hiromi Yoshida, Fumio Sugawara, Kengo Sakaguchi, Yoshiyuki Mizushina Biochemical pharmacology 2003 new
A novel type of replicative enzyme harbouring ATPase, primase and DNA polymerase activity. Georg Lipps, Susanne Röther, Christina Hart, Gerhard Krauss The EMBO journal 2003 topics set
Steered molecular dynamics simulation on the binding of NNRTI to HIV-1 RT. Lingling Shen, Jianhua Shen, Xiaomin Luo, Feng Cheng, Yechun Xu, Kaixian Chen, Edward Arnold, Jianping Ding, Hualiang Jiang Biophysical journal 2003 pols set
Mutation of amino acids in the connection domain of human immunodeficiency virus type 1 reverse transcriptase that contact the template-primer affects RNase H activity. John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes J Virol 2003 pols set
Real-time kinetics of the interaction between the two subunits, Escherichia coli thioredoxin and gene 5 protein of phage T7 DNA polymerase. Netai C Singha, Alexios Vlamis-Gardikas, Arne Holmgren The Journal of biological chemistry 2003 pols set
Maize DNA polymerase alpha is phosphorylated by a PCNA-associated cyclin/Cdk complex: effect of benzyladenine. Edurne Gómez Roig, Jorge M Vázquez-Ramos J Plant Physiol 2003 new
Study of MICA alleles in 201 African Americans by multiplexed single nucleotide extension (MSNE) typing. Yongqing Zhang, Mei Han, Robert Vorhaben, Chris Giang, Bhavna Lavingia, Peter Stastny Human immunology 2003 new
129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation. John P McDonald, Ekaterina G Frank, Brian S Plosky, Igor B Rogozin, Chikahide Masutani, Fumio Hanaoka, Roger Woodgate, Patricia J Gearhart J Exp Med 2003 new
The DNA binding domain of the gene 2.5 single-stranded DNA-binding protein of bacteriophage T7. Edel M Hyland, Lisa F Rezende, Charles C Richardson The Journal of biological chemistry 2003 pols set
A single-stranded DNA-binding protein of bacteriophage T7 defective in DNA annealing. Lisa F Rezende, Smaranda Willcox, Jack D Griffith, Charles C Richardson The Journal of biological chemistry 2003 pols set
Modular architecture of the bacteriophage T7 primase couples RNA primer synthesis to DNA synthesis. Masato Kato, Takuhiro Ito, Gerhard Wagner, Charles C Richardson, Tom Ellenberger Molecular cell 2003 new
Phe 771 of Escherichia coli DNA polymerase I (Klenow fragment) is the major site for the interaction with the template overhang and the stabilization of the pre-polymerase ternary complex. Aashish Srivastava, Kamalendra Singh, Mukund J Modak Biochemistry 2003 pols set
Damage repair DNA polymerases Y. Wei Wen Yang Current opinion in structural biology 2003 pols set
Regulated over-expression of DNA polymerase beta mediates early onset cataract in mice. Robert W Sobol, Julie F Foley, Abraham Nyska, Michael G Davidson, Samuel H Wilson DNA repair 2003 new
Participation of DNA polymerase II in the increased precise excision of Tn10. Rosa Nagel, Ana Chan DNA repair 2003 new
Expression and purification of recombinant Kaposi's sarcoma-associated herpesvirus DNA polymerase using a Baculovirus vector system. Dorjbal Dorjsuren, Yunden Badralmaa, Judy Mikovits, Aiqun Li, Robert Fisher, Robert P Ricciardi, Robert Shoemaker, Shizuko Sei Protein Expr Purif 2003 new
Effects of dipeptide insertions between codons 69 and 70 of human immunodeficiency virus type 1 reverse transcriptase on primer unblocking, deoxynucleoside triphosphate inhibition, and DNA chain elongation. Peter R Meyer, Johan Lennerstrand, Suzanne E Matsuura, Brendan A Larder, Walter A Scott J Virol 2003 topics set
Multiple roles for kinases in DNA replication. Ghislaine Henneke, Stéphane Koundrioukoff, Ulrich Hübscher EMBO reports 2003 new
TMC125 exerts similar initial antiviral potency as a five-drug, triple class antiretroviral regimen. Sanjay U C Sankatsing, Gerrit J Weverling, Monika Peeters, Gerben van't Klooster, Boris Gruzdev, Aza Rakhmanova, Sven A Danner, Suzanne Jurriaans, Jan M Prins, Joep M A Lange AIDS 2003 new
Nucleotide-induced conformational changes in an isolated Escherichia coli DNA polymerase III clamp loader subunit. Marjetka Podobnik, Tanya F Weitze, Mike E O'Donnell, John Kuriyan Structure (London, England : 1993) 2003 topics set
Patterns of point mutations associated with antiretroviral drug treatment failure in CRF01_AE (subtype E) infection differ from subtype B infection. Koyo Ariyoshi, Masakazu Matsuda, Hideka Miura, Sachiko Tateishi, Kaneo Yamada, Wataru Sugiura Journal of acquired immune deficiency syndromes 2003 pols set
Cold-sensitive mutants of Taq DNA polymerase provide a hot start for PCR. Milko B Kermekchiev, Anatoly Tzekov, Wayne M Barnes Nucleic acids research 2003 partial results
DNA polymerase beta gene expression: the promoter activator CREB-1 is upregulated in Chinese hamster ovary cells by DNA alkylating agent-induced stress. Feng He, Xiao-Ping Yang, Deepak K Srivastava, Samuel H Wilson Biological chemistry 2003 new
Translesion synthesis past acrolein-derived DNA adduct, gamma -hydroxypropanodeoxyguanosine, by yeast and human DNA polymerase eta. Irina G Minko, M Todd Washington, Manorama Kanuri, Louise Prakash, Satya Prakash, R Stephen Lloyd The Journal of biological chemistry 2003 pols set
Rapid segmental and subdomain motions of DNA polymerase beta. Soon-Jong Kim, William A Beard, John Harvey, David D Shock, Jay R Knutson, Samuel H Wilson The Journal of biological chemistry 2003 topics set
Poly(ADP-ribose) polymerase-1 (PARP-1) is required in murine cell lines for base excision repair of oxidative DNA damage in the absence of DNA polymerase beta. Florence Le Page, Valerie Schreiber, Claudine Dherin, Gilbert de Murcia, Serge Boiteux The Journal of biological chemistry 2003 new
The base substitution fidelity of DNA polymerase beta-dependent single nucleotide base excision repair. Toshiro Matsuda, Brian J Vande Berg, Katarzyna Bebenek, Wendy P Osheroff, Samuel H Wilson, Thomas A Kunkel The Journal of biological chemistry 2003 new
Inhibitory effect of pyridoxal 5'-phosphate on endothelial cell proliferation, replicative DNA polymerase and DNA topoisomerase. Kiminori Matsubara, Hiroaki Matsumoto, Yoshiyuki Mizushina, Jung Sup Lee, Norihisa Kato Int J Mol Med 2003 new
Human proliferating cell nuclear antigen, poly(ADP-ribose) polymerase-1, and p21waf1/cip1. A dynamic exchange of partners. Isabelle Frouin, Giovanni Maga, Marco Denegri, Federica Riva, Monica Savio, Silvio Spadari, Ennio Prosperi, A Ivana Scovassi The Journal of biological chemistry 2003 new
The carboxyl-terminal domain of bacteriophage T7 single-stranded DNA-binding protein modulates DNA binding and interaction with T7 DNA polymerase. Zheng-Guo He, Lisa F Rezende, Smaranda Willcox, Jack D Griffith, Charles C Richardson The Journal of biological chemistry 2003 pols set
The Gly-952 residue of Saccharomyces cerevisiae DNA polymerase alpha is important in discriminating correct deoxyribonucleotides from incorrect ones. Siripan Limsirichaikul, Masanori Ogawa, Atsuko Niimi, Shigenori Iwai, Takashi Murate, Shonen Yoshida, Motoshi Suzuki The Journal of biological chemistry 2003 topics set
Localization of the deoxyribose phosphate lyase active site in human DNA polymerase iota by controlled proteolysis. Rajendra Prasad, Katarzyna Bebenek, Esther W Hou, David D Shock, William A Beard, Roger Woodgate, Thomas A Kunkel, Samuel H Wilson The Journal of biological chemistry 2003 pols set
Molecular action mode of Hippospongic acid A, an inhibitor of gastrulation of starfish embryos. Yoshiyuki Mizushina, Chikako Murakami, Hirosato Takikawa, Nobuyuki Kasai, Xianai Xu, Kenji Mori, Masahiko Oshige, Tsuyoshi Yamaguchi, Mineo Saneyoshi, Noriko Shimazaki, Osamu Koiwai, Hiromi Yoshida, Fumio Sugawara, Kengo Sakaguchi Journal of biochemistry 2003 new
Biochemical characterization of interactions between DNA polymerase and single-stranded DNA-binding protein in bacteriophage RB69. Siyang Sun, Yousif Shamoo The Journal of biological chemistry 2003 complete
HIV-1 resistance profile of the novel nucleoside reverse transcriptase inhibitor beta-D-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine (Reverset). Romas Geleziunas, Karen Gallagher, Hangchun Zhang, Lee Bacheler, Sena Garber, Jing-Tao Wu, Guoen Shi, Michael J Otto, Raymond F Schinazi, Susan Erickson-Viitanen Antiviral chemistry & chemotherapy 2003 pols set
POLG mutations in sporadic mitochondrial disorders with multiple mtDNA deletions. Alessio Di Fonzo, Andreina Bordoni, Marco Crimi, Galbiati Sara, Roberto Del Bo, Nereo Bresolin, Giacomo P Comi Human mutation 2003 pols set
Function and assembly of the bacteriophage T4 DNA replication complex: interactions of the T4 polymerase with various model DNA constructs. Emmanuelle Delagoutte, Peter H von Hippel The Journal of biological chemistry 2003 complete
Saccharomyces cerevisiae DNA polymerase epsilon and polymerase sigma interact physically and functionally, suggesting a role for polymerase epsilon in sister chromatid cohesion. Shaune Edwards, Caroline M Li, Daniel L Levy, Jessica A Brown, Peter M Snow, Judith L Campbell Molecular and cellular biology 2003 topics set
Thermodynamics of the binding of Thermus aquaticus DNA polymerase to primed-template DNA. Kausiki Datta, Vince J LiCata Nucleic acids research 2003 pols set
Dissociation of DNA polymerase alpha-primase complex during meiosis in Coprinus cinereus. Satoshi Namekawa, Fumika Hamada, Tomoyuki Sawado, Satomi Ishii, Takayuki Nara, Takashi Ishizaki, Takashi Ohuchi, Takao Arai, Kengo Sakaguchi Eur J Biochem 2003 new
Human DNA polymerase lambda possesses terminal deoxyribonucleotidyl transferase activity and can elongate RNA primers: implications for novel functions. Kristijan Ramadan, Giovanni Maga, Igor V Shevelev, Giuseppe Villani, Luis Blanco, Ulrich Hübscher Journal of molecular biology 2003 pols set
Use of 2-aminopurine fluorescence to examine conformational changes during nucleotide incorporation by DNA polymerase I (Klenow fragment). Vandana Purohit, Nigel D F Grindley, Catherine M Joyce Biochemistry 2003 topics set
Cloning, expression, purification, and crystallisation of HIV-2 reverse transcriptase. Louise E Bird, Phillip P Chamberlain, Guillaume B E Stewart-Jones, Jingshan Ren, David I Stuart, David K Stammers Protein expression and purification 2003 partial results
Okazaki fragment maturation in yeast. II. Cooperation between the polymerase and 3'-5'-exonuclease activities of Pol delta in the creation of a ligatable nick. YongHwan Jin, Rao Ayyagari, MichaelA Resnick, DmitryA Gordenin, PeterMJ Burgers The Journal of biological chemistry 2003 new
Base excision repair intermediates induce p53-independent cytotoxic and genotoxic responses. Robert W Sobol, Maria Kartalou, Karen H Almeida, Donna F Joyce, Bevin P Engelward, Julie K Horton, Rajendra Prasad, Leona D Samson, Samuel H Wilson The Journal of biological chemistry 2003 new
Nonnucleoside HIV-1 reverse transcriptase inhibitors: Part I. Synthesis and structure-activity relationship of 1-alkoxymethyl-5-alkyl-6-naphthylmethyl uracils as HEPT analogues. Ge Meng, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Chemical & pharmaceutical bulletin 2003 pols set
Stimulation of human DNA polymerase epsilon by MDM2. Hitomi Asahara, Yingqian Li, Jill Fuss, Dale S Haines, Nikolina Vlatkovic, Mark T Boyd, Stuart Linn Nucleic acids research 2003 pols set
Human DNA polymerase kappa uses template-primer misalignment as a novel means for extending mispaired termini and for generating single-base deletions. William T Wolfle, M Todd Washington, Louise Prakash, Satya Prakash Genes Dev 2003 pols set
Didanosine, interferon-alfa and ribavirin: a highly synergistic combination with potential activity against HIV-1 and hepatitis C virus. Marina B Klein, Nadia Campeol, Richard G Lalonde, Bluma G Brenner, Mark A. Wainberg AIDS (London, England) 2003 new
POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells. Masayuki Seki, Federica Marini, Richard D Wood Nucleic acids research 2003 topics set
The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA. Vladimir P Bermudez, Yoshimasa Maniwa, Inger Tappin, Keiko Ozato, Kyoko Yokomori, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 2003 new
Fidelity of DNA polymerase delta holoenzyme from Saccharomyces cerevisiae: the sliding clamp proliferating cell nuclear antigen decreases its fidelity. Keiji Hashimoto, Kikuo Shimizu, Naomi Nakashima, Akio Sugino Biochemistry 2003 pols set
The human checkpoint Rad protein Rad17 is chromatin-associated throughout the cell cycle, localizes to DNA replication sites, and interacts with DNA polymerase epsilon. Sean M Post, Alan E Tomkinson, Eva Y-H P Lee Nucleic acids research 2003 new
Retroviral mutation rates and reverse transcriptase fidelity. Evguenia S Svarovskaia, Sara R Cheslock, Wen-Hui Zhang, Wei-Shau Hu, Vinay K Pathak Front Biosci 2003 pols set
Mechanism of nucleotide incorporation opposite a thymine-thymine dimer by yeast DNA polymerase eta. M Todd Washington, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2003 new
The hepatitis B virus polymerase mutation rtV173L is selected during lamivudine therapy and enhances viral replication in vitro. William E Delaney, Huiling Yang, Christopher E Westland, Kalyan Das, Edward Arnold, Craig S Gibbs, Michael D Miller, Shelly Xiong Journal of virology 2003 new
An error-prone family Y DNA polymerase (DinB homolog from Sulfolobus solfataricus) uses a 'steric gate' residue for discrimination against ribonucleotides. Angela M DeLucia, Nigel D F Grindley, Catherine M Joyce Nucleic acids research 2003 new
Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2. Rao Ayyagari, XavierV Gomes, DmitryA Gordenin, PeterMJ Burgers The Journal of biological chemistry 2003 new
Solution structure of the lyase domain of human DNA polymerase lambda. Eugene F DeRose, Thomas W Kirby, Geoffrey A Mueller, Katarzyna Bebenek, Miguel Garcia-Diaz, Luis Blanco, Thomas A Kunkel, Robert E London Biochemistry 2003 topics set
Real-time detection of nucleotide incorporation during complementary DNA strand synthesis. Alexander Krieg, Stephan Laib, Thomas Ruckstuhl, Stefan Seeger Chembiochem 2003 topics set
Influence of DNA aptamer structure on the specificity of binding to Taq DNA polymerase. O Yu Yakimovich, Ya I Alekseev, A V Maksimenko, O L Voronina, V G Lunin Biochemistry (Mosc) 2003 pols set
Cloning and characterization of a novel member of the human ATF/CREB family: ATF2 deletion, a potential regulator of the human DNA polymerase beta promoter. Yau-Jan Chyan, Teresa Y Rawson, Samuel H Wilson Gene 2003 pols set
Discovery of DNA polymerase. I. Robert Lehman The Journal of biological chemistry 2003 new
Viral DNA polymerase mutations associated with drug resistance in human cytomegalovirus. Sunwen Chou, Nell S Lurain, Kenneth D Thompson, Richard C Miner, W Lawrence Drew J Infect Dis 2003 new
Yeast DNA polymerase zeta is an efficient extender of primer ends opposite from 7,8-dihydro-8-Oxoguanine and O6-methylguanine. Lajos Haracska, Satya Prakash, Louise Prakash Molecular and cellular biology 2003 new
Synthesis of substituted 6-anilinouracils and their inhibition of DNA polymerase IIIC and Gram-positive bacterial growth. Chengxin Zhi, Zheng-Yu Long, Joseph Gambino, Wei-Chu Xu, Neal C Brown, Marjorie H Barnes, Michelle M Butler, William A LaMarr, George E Wright J Med Chem 2003 new
Mechanism of loading the Escherichia coli DNA polymerase III beta sliding clamp on DNA. Bona fide primer/templates preferentially trigger the gamma complex to hydrolyze ATP and load the clamp. Brandon Ason, Renita Handayani, Christopher R Williams, Jeffrey G Bertram, Manju M Hingorani, Mike E O'Donnell, Myron F Goodman, Linda B Bloom The Journal of biological chemistry 2003 pols set
Inducible expression of a dominant negative DNA polymerase-gamma depletes mitochondrial DNA and produces a rho0 phenotype. Mona Jazayeri, Alexander Andreyev, Yvonne Will, Manus Ward, Christen M Anderson, William Clevenger The Journal of biological chemistry 2003 new
Thermostable DNA polymerase from Thermus thermophilus B35: preparation and study of a modified form of the enzyme with high affinity to ddNTP. A G Akishev, Nadejda I Rechkunova, J E Tomilova, Natalia A Lebedeva, Olga I Lavrik, S Kh Degtyarev Biochemistry (Mosc) 2003 new
Double-stranded DNA binding properties of Saccharomyces cerevisiae DNA polymerase epsilon and of the Dpb3p-Dpb4p subassembly. Toshiaki Tsubota, Satoko Maki, Hajime Kubota, Akio Sugino, Hisaji Maki Genes Cells 2003 pols set
Extended stability of Taq DNA polymerase and T4 DNA ligase at various temperatures. Jim Youngblom BioTechniques 2003 pols set
Structural insights into the origins of DNA polymerase fidelity. William A Beard, Samuel H Wilson Structure (London, England : 1993) 2003 topics set
The N2-ethylguanine and the O6-ethyl- and O6-methylguanine lesions in DNA: contrasting responses from the "bypass" DNA polymerase eta and the replicative DNA polymerase alpha. Fred W Perrino, Patrick Blans, Scott Harvey, Stacy L Gelhaus, Colleen McGrath, Steven A Akman, G Scott Jenkins, William R Lacourse, James C Fishbein Chemical research in toxicology 2003 pols set
Characterization of the active site of DNA polymerase beta by molecular dynamics and quantum chemical calculation. Robert C Rittenhouse, Wlodzimierz K Apostoluk, John H Miller, T P Straatsma Proteins 2003 new
The herpes simplex virus type 1 DNA polymerase processivity factor increases fidelity without altering pre-steady-state rate constants for polymerization or excision. Murari Chaudhuri, Liping Song, Deborah S Parris The Journal of biological chemistry 2003 new
An unnatural base pair for efficient incorporation of nucleotide analogs into RNAs. Ichiro Hirao, Tsuneo Mitsui, Michiko Kimoto, Yoko Harada, Shigeyuki Yokoyama Nucleic Acids Res Suppl 2003 topics set
The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity. Jeanine A Harrigan, Patricia L Opresko, Cayetano von Kobbe, Padmini S Kedar, Rajendra Prasad, Samuel H Wilson, Vilhelm A Bohr The Journal of biological chemistry 2003 new
Translesion synthesis past platinum DNA adducts by human DNA polymerase mu. Jody M Havener, Stephanie A Nick McElhinny, Ekaterina Bassett, Michele Gauger, Dale A Ramsden, Stephen G Chaney Biochemistry 2003 pols set
phi 29 DNA polymerase residue Leu384, highly conserved in motif B of eukaryotic type DNA replicases, is involved in nucleotide insertion fidelity. Verónica Truniger, José María Lázaro, Miguel de Vega, Luis Blanco, Margarita Salas The Journal of biological chemistry 2003 pols set
The Y181C substitution in 3'-azido-3'-deoxythymidine-resistant human immunodeficiency virus, type 1, reverse transcriptase suppresses the ATP-mediated repair of the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer. Boulbaba Selmi, Jerome Deval, Karine Alvarez, Joelle Boretto, Simon Sarfati, Catherine Guerreiro, Bruno Canard The Journal of biological chemistry 2003 topics set
Effects of vinylphosphonate internucleotide linkages on the cleavage specificity of exonuclease III and on the activity of DNA polymerase I. Zara A Doddridge, Richard D Bertram, Christopher J Hayes, Panos Soultanas Biochemistry 2003 new
Mechanism of the delta wrench in opening the beta sliding clamp. Chiara Indiani, Mike E O'Donnell The Journal of biological chemistry 2003 topics set
Base excision repair deficiency caused by polymerase beta haploinsufficiency: accelerated DNA damage and increased mutational response to carcinogens. Diane C Cabelof, ZhongMao Guo, Julian J Raffoul, Robert W Sobol, Samuel H Wilson, Arlan Richardson, Ahmad R Heydari Cancer research 2003 new
A covalent linkage between the gene 5 DNA polymerase of bacteriophage T7 and Escherichia coli thioredoxin, the processivity factor: fate of thioredoxin during DNA synthesis. Donald E Johnson, Charles C Richardson The Journal of biological chemistry 2003 new
Diminished RNA primer usage associated with the L74V and M184V mutations in the reverse transcriptase of human immunodeficiency virus type 1 provides a possible mechanism for diminished viral replication capacity. Karidia Diallo, Bruno Marchand, Xin Wei, Luciano Cellai, Matthias Götte, Mark A. Wainberg Journal of virology 2003 pols set
Variants of DNA polymerase Beta extend mispaired DNA due to increased affinity for nucleotide substrate. Amit M Shah, Mausumi Maitra, Joann B Sweasy Biochemistry 2003 new
A mutation in the 3' region of the human immunodeficiency virus type 1 reverse transcriptase (Y318F) associated with nonnucleoside reverse transcriptase inhibitor resistance. P Richard Harrigan, Mahboob Salim, David K Stammers, Brian Wynhoven, Zabrina L Brumme, Paula McKenna, Brendan A Larder, S D Kemp Journal of virology 2002 pols set
Discrimination against purine-pyrimidine mispairs in the polymerase active site of DNA polymerase I: a structural explanation. Dana T Minnick, Lingfeng Liu, Nigel D F Grindley, Thomas A Kunkel, Catherine M Joyce Proceedings of the National Academy of Sciences of the United States of America 2002 new
Role of human DNA polymerase kappa as an extender in translesion synthesis. Lajos Haracska, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2002 pols set
Highlights in the development of new antiviral agents. Erik De Clercq Mini reviews in medicinal chemistry 2002 pols set
[Recent advance in DNA polymerase research: discovery of the new molecular species]. Shonen Yoshida, Fumio Hanaoka Seikagaku. The Journal of Japanese Biochemical Society 2002 new
trans-Lesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases. Olga Rechkoblit, Yongqing Zhang, Dongyu Guo, Zhengqiang Wang, Shantu Amin, Jacek Krzeminsky, Natalia Louneva, Nicholas E Geacintov The Journal of biological chemistry 2002 new
Using 2-aminopurine fluorescence to detect base unstacking in the template strand during nucleotide incorporation by the bacteriophage T4 DNA polymerase. Subhrangsu S Mandal, Elizabeth Fidalgo da Silva, Linda J Reha-Krantz Biochemistry 2002 partial results
Effects of specific zidovudine resistance mutations and substrate structure on nucleotide-dependent primer unblocking by human immunodeficiency virus type 1 reverse transcriptase. Peter R Meyer, Suzanne E Matsuura, Adviye A Tolun, Ingrid Pfeifer, Antero G So, John W Mellors, Walter A Scott Antimicrob Agents Chemother 2002 complete Walter A Scott*
Purification, separation, and identification of the human mtDNA polymerase with and without its accessory subunit. Matthew J Longley, William C Copeland Methods in molecular biology (Clifton, N.J.) 2002 new
New class of HIV integrase inhibitors that block viral replication in cell culture. Christophe Pannecouque, Wim Pluymers, Bénédicte Van Maele, Victor Tetz, Peter Cherepanov, Erik De Clercq, Myriam Witvrouw, Zeger Debyser Current biology : CB 2002 pols set
Purification strategies for Drosophila mtDNA replication proteins in native and recombinant form. DNA polymerase gamma. Carol L Farr, Laurie S Kaguni Methods in molecular biology (Clifton, N.J.) 2002 new
Multidrug-resistant HIV-1 reverse transcriptase: involvement of ribonucleotide-dependent phosphorolysis in cross-resistance to nucleoside analogue inhibitors. Antonio Mas, Blanca M Vázquez-Alvarez, Esteban Domingo, L Menéndez-Arias Journal of molecular biology 2002 topics set
The processivity factor beta controls DNA polymerase IV traffic during spontaneous mutagenesis and translesion synthesis in vivo. Nathalie Lenne-Samuel, Jérôme E Wagner, Hélène Etienne, Robert P P Fuchs EMBO Rep 2002 complete Jérôme E Wagner*
DNA polymerase V-dependent mutator activity in an SOS-induced Escherichia coli strain with a temperature-sensitive DNA polymerase III. Andrew R Timms, Bryn A Bridges Mutation research 2002 new
Hydrolysis of the 5'-p-nitrophenyl ester of TMP by the proofreading exonuclease (epsilon) subunit of Escherichia coli DNA polymerase III. Samir M Hamdan, Esther M Bulloch, Phillip R Thompson, Jennifer L Beck, Ji Yeon Yang, Jeffrey A Crowther, Penelope E Lilley, Paul D Carr, David L Ollis, Susan E Brown, Nicholas E Dixon Biochemistry 2002 pols set
Prevalence and origin of HIV-1 group M subtypes among patients attending a Belgian hospital in 1999. Joke Snoeck, Sonia Van Dooren, Kristel Van Laethem, Inge Derdelinckx, Eric Van Wijngaerden, Erik De Clercq, Anne-Mieke Vandamme Virus research 2002 pols set
A plant phytotoxin, solanapyrone A, is an inhibitor of DNA polymerase beta and lambda. Yoshiyuki Mizushina, Shinji Kamisuki, Nobuyuki Kasai, Noriko Shimazaki, Masaharu Takemura, Hitomi Asahara, Stuart Linn, Shonen Yoshida, Akio Matsukage, Osamu Koiwai, Fumio Sugawara, Hiromi Yoshida, Kengo Sakaguchi The Journal of biological chemistry 2002 pols set
Bone marrow transplantation in a child with Wiskott-Aldrich syndrome latently infected with acyclovir-resistant (ACV(r)) herpes simplex virus type 1: emergence of foscarnet-resistant virus originating from the ACV(r) virus. Masayuki Saijo, Yukiharu Yasuda, Hiromasa Yabe, Shunichi Kato, Tatsuo Suzutani, Erik De Clercq, Masahiro Niikura, Akihiko Maeda, Ichiro Kurane, Shigeru Morikawa Journal of medical virology 2002 new
Mechanistic studies to understand the progressive development of resistance in human immunodeficiency virus type 1 reverse transcriptase to abacavir. Adrian S Ray, Aravind Basavapathruni, Karen S Anderson The Journal of biological chemistry 2002 topics set
Human DNA polymerase epsilon colocalizes with proliferating cell nuclear antigen and DNA replication late, but not early, in S phase. Jill Fuss, Stuart Linn The Journal of biological chemistry 2002 pols set
Human DNA polymerase kappa bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides. Paula L Fischhaber, Valerie L Gerlach, William J Feaver, Zafer Hatahet, Susan S Wallace, Errol C Friedberg The Journal of biological chemistry 2002 pols set
The deoxyribo-mode expression of primase activities of the primase-alpha DNA polymerase enzyme complex associated with nucleoprotein complexes harboring an extrachromosomal DNA identical with avian myeloblastosis virus core-bound DNA: influencing by carbonyldiphosphonate, mimosine and butylphenyl deoxyguanosine-5'-triphosphate. J Ríman Acta Virol 2002 new
Loss of DNA polymerase beta stacking interactions with templating purines, but not pyrimidines, alters catalytic efficiency and fidelity. William A Beard, David D Shock, Xiao-Ping Yang, Saundra F DeLauder, Samuel H Wilson The Journal of biological chemistry 2002 new
2-Chloro-3-pyridin-3-yl-5,6,7,8-tetrahydroindolizine-1-carboxamide (CMV423), a new lead compound for the treatment of human cytomegalovirus infections. Robert Snoeck, Graciela Andrei, Bahram Bodaghi, Laurence Lagneaux, Dirk Daelemans, Erik De Clercq, Johan Neyts, Dominique Schols, Lieve Naesens, Susan Michelson, Dominique Bron, Michael J Otto, Anne Bousseau, Conception Nemecek, Christine Roy Antiviral research 2002 new
Inhibition of human immunodeficiency virus type 1 integration by diketo derivatives. Wim Pluymers, Godwin Pais, Bénédicte Van Maele, Christophe Pannecouque, Valery Fikkert, Terrence R Burke, Erik De Clercq, Myriam Witvrouw, Nouri Neamati, Zeger Debyser Antimicrobial agents and chemotherapy 2002 pols set
The proofreading 3'-->5' exonuclease activity of DNA polymerases: a kinetic barrier to translesion DNA synthesis. Vineeta Khare, Kristin A Eckert Mutation research 2002 partial results
Mutant Thermotoga neapolitana DNA polymerase I: altered catalytic properties for non-templated nucleotide addition and incorporation of correct nucleotides. Shu-Wei Yang, Mekbib Astatke, Jason Potter, Deb K Chatterjee Nucleic acids research 2002 pols set
Protein determinants of RNA binding by DNA polymerase of the T4-related bacteriophage RB69. Vasiliy M Petrov, San-San Ng, Jim D Karam The Journal of biological chemistry 2002 complete
New anti-HIV agents and targets. Erik De Clercq Medicinal research reviews 2002 pols set
Petasiphenol: a DNA polymerase lambda inhibitor. Yoshiyuki Mizushina, Shinji Kamisuki, Nobuyuki Kasai, Tomomi Ishidoh, Noriko Shimazaki, Masaharu Takemura, Hitomi Asahara, Stuart Linn, Shonen Yoshida, Osamu Koiwai, Fumio Sugawara, Hiromi Yoshida, Kengo Sakaguchi Biochemistry 2002 topics set
Multidrug-resistant HIV-1 RNA and proviral DNA variants harboring new dipeptide insertions in the reverse transcriptase pol gene. Laurent Andréoletti, Laurence Weiss, Ali Si-Mohamed, Christophe Piketty, Thierry Prazuck, Gérard Calamy, Jean-Elie Malkin, Mathieu Matta, François-Xavier Mbopi-Kéou, François Clavel, Michel D Kazatchkine, Laurent Bélec J Acquir Immune Defic Syndr 2002 topics set
Two distinct modes of RecA action are required for DNA polymerase V-catalyzed translesion synthesis. Phuong Pham, Erica M Seitz, Sergei Saveliev, Xuan Shen, Roger Woodgate, Michael M Cox, Myron F Goodman Proceedings of the National Academy of Sciences of the United States of America 2002 new
Assessing the contribution of the herpes simplex virus DNA polymerase to spontaneous mutations. Karen E Duffy, Matthew R Quail, Tammy T Nguyen, Robert J Wittrock, Joan O Bartus, Wendy M Halsey, Jeffry J Leary, Teresa H Bacon, Robert T Sarisky BMC Infect Dis 2002 new
Efficient and high fidelity incorporation of dye-terminators by a novel archaeal DNA polymerase mutant. Bahram Arezi, Connie J Hansen, Holly H Hogrefe Journal of molecular biology 2002 partial results
Quantitative measurement of translesion replication in human cells: evidence for bypass of abasic sites by a replicative DNA polymerase. Sharon Avkin, Sheera Adar, Gil Blander, Zvi Livneh Proceedings of the National Academy of Sciences of the United States of America 2002 new
Molecular analysis of mutations in DNA polymerase eta in xeroderma pigmentosum-variant patients. Bernard C Broughton, Agnes M Cordonnier, Wim J Kleijer, Nicolaas G J Jaspers, Heather Fawcett, Anja Raams, Victor H Garritsen, Anne Stary, Marie-Françoise Avril, François Boudsocq, Chikahide Masutani, Fumio Hanaoka, Robert P P Fuchs, Alain Sarasin, Alan R Lehmann Proceedings of the National Academy of Sciences of the United States of America 2002 new
[DNA polymerase beta]. Akio Matsukage Seikagaku 2002 new
Multiple mitochondrial DNA polymerases in Trypanosoma brucei. Michele M Klingbeil, Shawn A Motyka, Paul T Englund Molecular cell 2002 new
Induction of a low level of microsatellite instability by overexpression of DNA polymerase Beta. Nazumi A Yamada, Rosann A Farber Cancer research 2002 new
Direct interaction of proliferating cell nuclear antigen with the small subunit of DNA polymerase delta. Xiaoqing Lu, Cheng-Keat Tan, Jin-Qiu Zhou, Min You, L Michael Carastro, Kathleen M Downey, Antero G So The Journal of biological chemistry 2002 new
Polkappa protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene. Tomoo Ogi, Yoichi Shinkai, Kiyoji Tanaka, Haruo Ohmori Proceedings of the National Academy of Sciences of the United States of America 2002 topics set
Control of complex formation of DNA polymerase alpha-primase and cell-free DNA replication by the C-terminal amino acids of the largest subunit p180. R W P Smith, Heinz Peter Nasheuer FEBS letters 2002 new
Substitutions of Phe61 located in the vicinity of template 5'-overhang influence polymerase fidelity and nucleoside analog sensitivity of HIV-1 reverse transcriptase. Timothy S Fisher, Vinayaka R Prasad The Journal of biological chemistry 2002 partial results
Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215. Phillip P Chamberlain, Jingshan Ren, Charles E Nichols, L Douglas, Johan Lennerstrand, Brendan A Larder, David I Stuart, David K Stammers J Virol 2002 topics set
Phi29 DNA polymerase residues Tyr59, His61 and Phe69 of the highly conserved ExoII motif are essential for interaction with the terminal protein. Ralf Eisenbrandt, José María Lázaro, Margarita Salas, Miguel de Vega Nucleic acids research 2002 partial results
Fidelity of Escherichia coli DNA polymerase IV. Preferential generation of small deletion mutations by dNTP-stabilized misalignment. Sawami Kobayashi, Michael R Valentine, Phuong Pham, Mike E O'Donnell, Myron F Goodman The Journal of biological chemistry 2002 partial results
The DNA-polymerase inhibiting activity of poly(beta-l-malic acid) in nuclear extract during the cell cycle of Physarum polycephalum. Sabine Doerhoefer, Christina Windisch, Bernhard Angerer, Olga I Lavrik, Bong-Seop Lee, Eggehard Holler Eur J Biochem 2002 new
Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota. Ahmad Faili, Said Aoufouchi, Eric Flatter, Quentin Guéranger, Claude-Agnès Reynaud, Jean-Claude Weill Nature 2002 pols set
Misalignment-mediated DNA polymerase beta mutations: comparison of microsatellite and frame-shift error rates using a forward mutation assay. Kristin A Eckert, Andrew Mowery, Suzanne E Hile Biochemistry 2002 new
Mutation of the catalytic domain of the foamy virus reverse transcriptase leads to loss of processivity and infectivity. Carolyn S Rinke, Paul L Boyer, Mark D Sullivan, Stephen H Hughes, Maxine L Linial Journal of virology 2002 new
Photoaffinity labeling of proteins in bovine testis nuclear extract. Natalia A Lebedeva, Nadejda I Rechkunova, Svetlana N Khodyreva, Alain Favre, Olga I Lavrik Biochemical and biophysical research communications 2002 new
Nontemplated nucleotide addition by HIV-1 reverse transcriptase. Marie-Pierre Golinelli, Stephen H Hughes Biochemistry 2002 pols set
The upr-1 gene encodes a catalytic subunit of the DNA polymerase zeta which is involved in damage-induced mutagenesis in Neurospora crassa. W Sakai, C Ishii, Hirokazu Inoue Mol Genet Genomics 2002 new
A dynamic RecA filament permits DNA polymerase-catalyzed extension of the invading strand in recombination intermediates. Liewei Xu, Kenneth J Marians The Journal of biological chemistry 2002 new
Polymerase beta simulations suggest that Arg258 rotation is a slow step rather than large subdomain motions per se. Linjing Yang, William A Beard, Samuel H Wilson, Suse Broyde, Tamar Schlick Journal of molecular biology 2002 topics set
Highly efficient labeling of DNA polymerases by a binary system of photoaffinity reagents. Natalia A Lebedeva, Dmitry M Kolpashchikov, Nadejda I Rechkunova, Svetlana N Khodyreva, Olga I Lavrik Biochemistry. Biokhimii͡a 2002 new
Nontemplated base addition by HIV-1 RT can induce nonspecific strand transfer in vitro. Marie-Pierre Golinelli, Stephen H Hughes Virology 2002 pols set
The roles of Klenow processing and flap processing activities of DNA polymerase I in chromosome instability in Escherichia coli K12 strains. Yuki Nagata, Kazumi Mashimo, Masakado Kawata, Kazuo Yamamoto Genetics 2002 new
Fapy.dA induces nucleotide misincorporation translesionally by a DNA polymerase. Michael O Delaney, Carissa J Wiederholt, Marc M Greenberg Angew Chem Int Ed Engl 2002 new
A molecular beacon for quantitative monitoring of the DNA polymerase reaction in real-time. Daniel Summerer, Andreas Marx Angewandte Chemie (International ed. in English) 2002 new
Expression of 5-lipoxygenase in pulmonary artery endothelial cells. Ying-Yi Zhang, Jennifer L Walker, Annong Huang, John F Keaney, Clary B Clish, Charles N Serhan, Joseph Loscalzo The Biochemical journal 2002 new
Involvement of DNA polymerase beta in DNA replication and mutagenic consequences. Laurence Servant, Anne Bieth, Hiroshi Hayakawa, Christophe Cazaux, Jean-Sébastien Hoffmann Journal of molecular biology 2002 new
Vitamin A-related compounds, all-trans retinal and retinoic acids, selectively inhibit activities of mammalian replicative DNA polymerases. Chikako Murakami, Masaharu Takemura, Yuichi Sugiyama, Shinji Kamisuki, Hitomi Asahara, Miho Kawasaki, Tomomi Ishidoh, Stuart Linn, Shonen Yoshida, Fumio Sugawara, Hiromi Yoshida, Kengo Sakaguchi, Yoshiyuki Mizushina Biochimica et biophysica acta 2002 new
Attenuation of DNA polymerase beta-dependent base excision repair and increased DMS-induced mutagenicity in aged mice. Diane C Cabelof, Julian J Raffoul, Sunitha Yanamadala, Cirlette Ganir, ZhongMao Guo, Ahmad R Heydari Mutation research 2002 new
Assembly, purification and crystallization of an active HIV-1 reverse transcriptase initiation complex. Janice D Pata, Bradford R King, Thomas A Steitz Nucleic acids research 2002 pols set
Motors and switches: AAA+ machines within the replisome. Megan J Davey, David Jeruzalmi, John Kuriyan, Mike E O'Donnell Nature reviews. Molecular cell biology 2002 topics set
A parallel synthesis scheme for generating libraries of DNA polymerase substrates and inhibitors. Heike Strobel, Laurence Dugué, Philippe Marlière, Sylvie Pochet Chembiochem 2002 new
Bax-induction gene therapy of pancreatic cancer. Elissa C Pirocanac, Rounak Nassirpour, Meng Yang, Jinwei Wang, Stephanie R Nardin, Jian Gu, Bingliang Fang, A R Moossa, Robert M Hoffman, Michael Bouvet The Journal of surgical research 2002 new
Human DNA polymerase mu (Pol mu) exhibits an unusual replication slippage ability at AAF lesion. Jean-Baptiste Duvauchelle, Luis Blanco, Robert P P Fuchs, Agnes M Cordonnier Nucleic acids research 2002 topics set
Physical and functional interactions of the tumor suppressor protein p53 and DNA polymerase alpha-primase. Christian Melle, Heinz Peter Nasheuer Nucleic acids research 2002 new
The "tale" of UmuD and its role in SOS mutagenesis. Martín Gonzalez, Roger Woodgate BioEssays : news and reviews in molecular, cellular and developmental biology 2002 new
Using 2-aminopurine fluorescence to measure incorporation of incorrect nucleotides by wild type and mutant bacteriophage T4 DNA polymerases. Elizabeth Fidalgo da Silva, Subhrangsu S Mandal, Linda J Reha-Krantz The Journal of biological chemistry 2002 complete
Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant. Jimmy Lindberg, Snaevar Sigurdsson, Seved Löwgren, Hans O Andersson, Christer Sahlberg, Rolf Noréen, Kerstin Fridborg, Haijiang Zhang, Torsten Unge Eur J Biochem 2002 topics set
In vitro nucleotide misinsertion opposite the oxidized guanosine lesions spiroiminodihydantoin and guanidinohydantoin and DNA synthesis past the lesions using Escherichia coli DNA polymerase I (Klenow fragment). Olga Kornyushyna, Aym M Berges, James G Muller, Cynthia J Burrows Biochemistry 2002 pols set
The accessory subunit of DNA polymerase gamma is essential for mitochondrial DNA maintenance and development in Drosophila melanogaster. Balaji Iyengar, Ningguang Luo, Carol L Farr, Laurie S Kaguni, Ana Regina Campos Proceedings of the National Academy of Sciences of the United States of America 2002 new
Direct activation of telomerase by EGF through Ets-mediated transactivation of TERT via MAP kinase signaling pathway. Yoshiko Maida, Satoru Kyo, Taro Kanaya, Zhengqiang Wang, Noriyuki Yatabe, Masaaki Tanaka, Mitsuhiro Nakamura, Masahide Ohmichi, Noriko Gotoh, Seishi Murakami, Masaki Inoue Oncogene 2002 new
Primer unblocking and rescue of DNA synthesis by azidothymidine (AZT)-resistant HIV-1 reverse transcriptase: comparison between initiation and elongation of reverse transcription and between (-) and (+) strand DNA synthesis. Mickael Rigourd, Chantal Ehresmann, Michael A. Parniak, Bernard Ehresmann, Roland Marquet The Journal of biological chemistry 2002 complete Roland Marquet*
Deregulated DNA polymerase beta strengthens ionizing radiation-induced nucleotidic and chromosomal instabilities. Mathilde Fréchet, Yvan Canitrot, Anne Bieth, Eugenia Dogliotti, Christophe Cazaux, Jean-Sébastien Hoffmann Oncogene 2002 new
[DNA polymerase epsilon]. Yasuo Kawasaki, Akio Sugino Seikagaku 2002 new
Model for the catalytic domain of the proofreading epsilon subunit of Escherichia coli DNA polymerase III based on NMR structural data. Eugene F DeRose, Dawei Li, Thomas A Darden, Scott Harvey, Fred W Perrino, Roel M Schaaper, Robert E London Biochemistry 2002 pols set
[Mechanism of translesion DNA synthesis by DNA polymerase zeta]. Yoshiki Murakumo Seikagaku 2002 new
TempliPhi, phi29 DNA polymerase based rolling circle amplification of templates for DNA sequencing. John R Nelson, Yuyang Christine Cai, Theresa L Giesler, Joseph W Farchaus, Shanmuuga T Sundaram, Maria Ortiz-Rivera, Lou P Hosta, Peter L Hewitt, J Anthony Mamone, C Palaniappan, Carl W Fuller BioTechniques 2002 partial results
LINEs and SINE-like elements of the protist Entamoeba histolytica. Katrina Van Dellen, Jessica Field, Zhengqiang Wang, Brendan Loftus, John Samuelson Gene 2002 new
Reconstitution of human DNA polymerase delta using recombinant baculoviruses: the p12 subunit potentiates DNA polymerizing activity of the four-subunit enzyme. Vladimir N Podust, Long-Sheng Chang, Robert Ott, Grigory L Dianov, Ellen Fanning The Journal of biological chemistry 2002 pols set
In search of authentic inhibitors of HIV-1 integration. Zeger Debyser, Peter Cherepanov, Bénédicte Van Maele, Erik De Clercq, Myriam Witvrouw Antiviral chemistry & chemotherapy 2002 pols set
Dissecting the fidelity of bacteriophage RB69 DNA polymerase: site-specific modulation of fidelity by polymerase accessory proteins. Anna Bebenek, Geraldine T Carver, Holly Kloos Dressman, Farid A Kadyrov, Joseph K Haseman, Vasiliy M Petrov, William H Konigsberg, Jim D Karam, John W Drake Genetics 2002 complete
Structural basis for proofreading during replication of the Escherichia coli chromosome. Samir M Hamdan, Paul D Carr, Susan E Brown, David L Ollis, Nicholas E Dixon Structure (London, England : 1993) 2002 topics set
[Monoclonal antibodies against human telomerase reverse transcriptase: preparation, characterization, and application]. Shaomin Yang, Bo Zhang, Junmei Wang, Songlin Liao, Jisheng Han, Jianping Wei, Lin Hou Zhonghua bing li xue za zhi Chinese journal of pathology 2002 new
Covalent trapping of human DNA polymerase beta by the oxidative DNA lesion 2-deoxyribonolactone. Michael S DeMott, Ergin Beyret, Donny Wong, Brian C Bales, Jae-Taeg Hwang, Marc M Greenberg, Bruce Demple The Journal of biological chemistry 2002 pols set
Directed evolution of novel polymerase activities: mutation of a DNA polymerase into an efficient RNA polymerase. Gang Xia, Liangjing Chen, Takashi Sera, Ming Fa, Peter G Schultz, Floyd E Romesberg Proceedings of the National Academy of Sciences of the United States of America 2002 pols set
Utility and accuracy of template-directed dye-terminator incorporation with fluorescence-polarization detection for genotyping single nucleotide polymorphisms. N Akula, Y S Chen, K Hennessy, T G Schulze, G Singh, F J McMahon BioTechniques 2002 topics set
Replication-dependent recruitment of the beta-subunit of DNA polymerase III from cytosolic spaces to replication forks in Escherichia coli. Toshinari Onogi, Katsufumi Ohsumi, Tsutomu Katayama, Sota Hiraga J Bacteriol 2002 pols set
Misincorporation and stalling at O(6)-methylguanine and O(6)-benzylguanine: evidence for inactive polymerase complexes. Adrienne M Woodside, F Peter Guengerich Biochemistry 2002 pols set
Physical interaction between proliferating cell nuclear antigen and replication factor C from Pyrococcus furiosus. Shigeki Matsumiya, Sonoko Ishino, Yoshizumi Ishino, Kosuke Morikawa Genes to cells : devoted to molecular & cellular mechanisms 2002 new
Molecular architecture of adenovirus DNA polymerase and location of the protein primer. Arjan B Brenkman, Elise C Breure, Peter C van der Vliet J Virol 2002 new
[Effect of human telomerase reverse transcriptase gene antisense oligodeoxynucleotide on telomerase activity in leukemia cells]. Dong-Mei He, Yongqing Zhang Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology 2002 new
Participation of active-site carboxylates of Escherichia coli DNA polymerase I (Klenow fragment) in the formation of a prepolymerase ternary complex. Rajiv Gangurde, Mukund J Modak Biochemistry 2002 pols set
Cell cycle-dependent dynamic association of cyclin/Cdk complexes with human DNA replication proteins. Isabelle Frouin, Alessandra Montecucco, Giuseppe Biamonti, Ulrich Hübscher, Silvio Spadari, Giovanni Maga The EMBO journal 2002 new
Lesion bypass in yeast cells: Pol eta participates in a multi-DNA polymerase process. Anne Bresson, Robert P P Fuchs The EMBO journal 2002 new
Kinetic study of various binding modes between human DNA polymerase beta and different DNA substrates by surface-plasmon-resonance biosensor. Pui Yan Tsoi, Mengsu Yang Biochem J 2002 pols set
Actions of derivatives of dehydroaltenusin, a new mammalian DNA polymerase alpha-specific inhibitor. Shinji Kamisuki, Chikako Murakami, Keisuke Ohta, Hiromi Yoshida, Fumio Sugawara, Kengo Sakaguchi, Yoshiyuki Mizushina Biochem Pharmacol 2002 pols set
Promoter clearance by T7 RNA polymerase. Initial bubble collapse and transcript dissociation monitored by base analog fluorescence. Cuihua Liu, Craig T Martin The Journal of biological chemistry 2002 topics set
Use of 2-aminopurine and tryptophan fluorescence as probes in kinetic analyses of DNA polymerase beta. Christopher A Dunlap, Ming-Daw Tsai Biochemistry 2002 topics set
Selective inhibition of the activities of both eukaryotic DNA polymerases and DNA topoisomerases by elenic acid. Yoshiyuki Mizushina, Chikako Murakami, Keisuke Ohta, Hirosato Takikawa, Kenji Mori, Hiromi Yoshida, Fumio Sugawara, Kengo Sakaguchi Biochemical pharmacology 2002 pols set
The second largest subunit of mouse DNA polymerase epsilon, DPE2, interacts with SAP18 and recruits the Sin3 co-repressor protein to DNA. Masahito Wada, Hiroshi Miyazawa, Rui-Sheng Wang, Takeshi Mizuno, Akira Sato, Makoto Asashima, Fumio Hanaoka J Biochem 2002 complete Takeshi Mizuno*
DNA polymerase clamp shows little turnover at established replication sites but sequential de novo assembly at adjacent origin clusters. Anje Sporbert, Anja Gahl, Richard Ankerhold, Heinrich Leonhardt, M Cristina Cardoso Molecular cell 2002 new
Human DNA polymerase lambda functionally and physically interacts with proliferating cell nuclear antigen in normal and translesion DNA synthesis. Giovanni Maga, Giuseppe Villani, Kristijan Ramadan, Igor V Shevelev, Nicolas Tanguy Le Gac, Luis Blanco, Giuseppina Blanca, Silvio Spadari, Ulrich Hübscher The Journal of biological chemistry 2002 pols set
A tight-binding mode of inhibition is essential for anti-human immunodeficiency virus type 1 virucidal activity of nonnucleoside reverse transcriptase inhibitors. Dimitrios Motakis, Michael A. Parniak Antimicrobial agents and chemotherapy 2002 pols set
DNA polymerase beta. Haitham T Idriss, Osama Al-Assar, Samuel H Wilson Int J Biochem Cell Biol 2002 topics set
Virulence and reduced fitness of simian immunodeficiency virus with the M184V mutation in reverse transcriptase. Koen K A Van Rompay, Tim B Matthews, Joanne Higgins, Don R Canfield, Ross P Tarara, Mark A. Wainberg, Raymond F Schinazi, Niels C Pedersen, Thomas W North Journal of virology 2002 pols set
Replication factor C from the hyperthermophilic archaeon Pyrococcus abyssi does not need ATP hydrolysis for clamp-loading and contains a functionally conserved RFC PCNA-binding domain. Ghislaine Henneke, Yannick Gueguen, Didier Flament, Philippe Azam, Joël Querellou, Jacques Dietrich, Ulrich Hübscher, Jean-Paul Raffin Journal of molecular biology 2002 new
DNA polymerase theta purified from human cells is a high-fidelity enzyme. Giovanni Maga, Igor V Shevelev, Kristijan Ramadan, Silvio Spadari, Ulrich Hübscher Journal of molecular biology 2002 new
Base composition of mononucleotide runs affects DNA polymerase slippage and removal of frameshift intermediates by mismatch repair in Saccharomyces cerevisiae. Hana Gragg, Brian D Harfe, Sue Jinks-Robertson Molecular and cellular biology 2002 new
A novel mechanism for inhibition of HIV-1 reverse transcriptase. A Geoffrey Skillman, Karl W Maurer, Diana C Roe, Margaret J Stauber, Dolan Eargle, Todd J A Ewing, Angelika Muscate, Elisabeth Davioud-Charvet, Maxine V Medaglia, Robert J Fisher, Edward Arnold, Hong Qiang Gao, Robert W Buckheit, Paul L Boyer, Stephen H Hughes, Irwin D Kuntz, George L Kenyon Bioorganic chemistry 2002 pols set
Mutations in the RNase H domain of HIV-1 reverse transcriptase affect the initiation of DNA synthesis and the specificity of RNase H cleavage in vivo. John G Julias, Mary Jane McWilliams, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes Proceedings of the National Academy of Sciences of the United States of America 2002 pols set
Inhibition of Klenow DNA polymerase and poly(A)-specific ribonuclease by aminoglycosides. Yan-Guo Ren, Javier Martínez, Leif A Kirsebom, Anders Virtanen RNA 2002 new
Mutational analysis of HIV-1 long terminal repeats to explore the relative contribution of reverse transcriptase and RNA polymerase II to viral mutagenesis. Patrick K O'Neil, Guoli Sun, Hong Yu, Yacov Ron, Joseph P Dougherty, Bradley D Preston The Journal of biological chemistry 2002 new
Hydrocephalus, situs inversus, chronic sinusitis, and male infertility in DNA polymerase lambda-deficient mice: possible implication for the pathogenesis of immotile cilia syndrome. Yosuke Kobayashi, Miho Watanabe, Yuki Okada, Hirofumi Sawa, Hiroyuki Takai, Makoto Nakanishi, Yosuke Kawase, Hiroshi Suzuki, Kazuo Nagashima, Kyoji Ikeda, Noboru Motoyama Molecular and cellular biology 2002 new
[Cloning of Ig Fab genes of patients with chronic B lymphocytic leukemia and sequences analysis of their variable regions]. Huifen Zhu, Feng Wang, Yongqing Zhang, Guanxin Shen Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 2002 new
Structure/function analysis of the Saccharomyces cerevisiae Trf4/Pol sigma DNA polymerase. Zhengqiang Wang, Irene B Castaño, Carrie Adams, Clemence Vu, David Fitzhugh, Michael F Christman Genetics 2002 new
Chimeric human immunodeficiency virus type 1 and feline immunodeficiency virus reverse transcriptases: role of the subunits in resistance/sensitivity to non-nucleoside reverse transcriptase inhibitors. Joeri Auwerx, Thomas W North, Bradley D Preston, George J Klarmann, Erik De Clercq, Jan Balzarini Molecular pharmacology 2002 pols set
A novel DNA polymerase homologous to Escherichia coli DNA polymerase I from a higher plant, rice (Oryza sativa L.). Seisuke Kimura, Yukinobu Uchiyama, Nobuyuki Kasai, Satoshi Namekawa, Ai Saotome, Tadamasa Ueda, Tsuyu Ando, Toyotaka Ishibashi, Masahiko Oshige, Tomoyuki Furukawa, Taichi Yamamoto, Junji Hashimoto, Kengo Sakaguchi Nucleic acids research 2002 new
Pol32, a subunit of Saccharomyces cerevisiae DNA polymerase delta, suppresses genomic deletions and is involved in the mutagenic bypass pathway. Meng-Er Huang, Anne-Gaëlle Rio, Marie-Dominique Galibert, Francis Galibert Genetics 2002 pols set
Two-step error-prone bypass of the (+)- and (-)-trans-anti-BPDE-N2-dG adducts by human DNA polymerases eta and kappa. Yongqing Zhang, Xiaoming Wu, Dongyu Guo, Olga Rechkoblit, Nicholas E Geacintov, Zhengqiang Wang Mutation research 2002 pols set
Activities of human DNA polymerase kappa in response to the major benzo[a]pyrene DNA adduct: error-free lesion bypass and extension synthesis from opposite the lesion. Yongqing Zhang, Xiaoming Wu, Dongyu Guo, Olga Rechkoblit, Zhengqiang Wang DNA repair 2002 pols set
Species specificity of simian virus 40 DNA replication in vitro requires multiple functions of human DNA polymerase alpha. Richard W P Smith, Claudia Steffen, Frank Grosse, Heinz Peter Nasheuer The Journal of biological chemistry 2002 pols set
Identification of delta helicase as the bovine homolog of HUPF1: demonstration of an interaction with the third subunit of DNA polymerase delta. L Michael Carastro, Cheng-Keat Tan, Manuel Selg, Hans-Martin Jack, Antero G So, Kathleen M Downey Nucleic acids research 2002 pols set
Pressure of zidovudine accelerates the reversion of lamivudine resistance-conferring M184V mutation in the reverse transcriptase of human immunodeficiency virus type 1. Karidia Diallo, Maureen Oliveira, Daniela D Moisi, Bluma G Brenner, Mark A. Wainberg, Matthias Götte Antimicrobial agents and chemotherapy 2002 new
Low frequencies of resistance among Staphylococcus and Enterococcus species to the bactericidal DNA polymerase inhibitor N(3)-hydroxybutyl 6-(3'-ethyl-4'-methylanilino) uracil. Michelle M Butler, Donna J Skow, Ryan O Stephenson, Patrick T Lyden, William A LaMarr, Kimberly A Foster Antimicrob Agents Chemother 2002 new
Implications of active site constraints on varied DNA polymerase selectivity. Michael Strerath, Janina Cramer, Tobias Restle, Andreas Marx Journal of the American Chemical Society 2002 topics set
Telomerase: biochemical considerations for enzyme and substrate. Colleen Kelleher, M Teresa Teixeira, Klaus Förstemann, Joachim Lingner Trends in biochemical sciences 2002 topics set
Correlation of the kinetics of finger domain mutants in RB69 DNA polymerase with its structure. Guangwei Yang, Matthew Franklin, Jinming Li, T C Lin, William H Konigsberg Biochemistry 2002 complete
[A novel mammalian DNA polymerase: DNA polymerase lambda (pol lambda)]. Hiroyuki Niida, Makoto Nakanishi Seikagaku 2002 pols set
Insulating behavior of lambda-DNA on the micron scale. Yong Zhang, R H Austin, J Kraeft, E C Cox, N P Ong Physical review letters 2002 new
Non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors: past, present, and future perspectives. Giuseppe Campiani, Anna Ramunno, Giovanni Maga, Vito Nacci, Caterina Fattorusso, Bruno Catalanotti, Elena Morelli, Ettore Novellino Current pharmaceutical design 2002 pols set
PCR performance of the highly thermostable proof-reading B-type DNA polymerase from Pyrococcus abyssi. Jacques Dietrich, Philippe Schmitt, Montserrat Zieger, Brigitte Preve, Jean-Luc Rolland, Hassan Chaabihi, Yannick Gueguen FEMS Microbiol Lett 2002 partial results
Translesion synthesis by human DNA polymerase eta across thymine glycol lesions. Rika Kusumoto, Chikahide Masutani, Shigenori Iwai, Fumio Hanaoka Biochemistry 2002 pols set
Reconstitution of the base excision repair pathway for 7,8-dihydro-8-oxoguanine with purified human proteins. Barbara Pascucci, Giovanni Maga, Ulrich Hübscher, M Bjoras, E Seeberg, Ian D Hickson, Giuseppe Villani, Cesare Giordano, Luciano Cellai, Eugenia Dogliotti Nucleic acids research 2002 new
Template requirements for de novo RNA synthesis by hepatitis C virus nonstructural protein 5B polymerase on the viral X RNA. Meehyein Kim, Hajeong Kim, Seong-Pil Cho, Mi-Kyung Min J Virol 2002 new
A functional and structural basis for TCR cross-reactivity in multiple sclerosis. Heather L E Lang, Helle Jacobsen, Shinji Ikemizu, Christina Andersson, Karl Harlos, Lars Madsen, Peter Hjorth, Leif Sondergaard, Arne Svejgaard, Kai Wucherpfennig, David I Stuart, John I Bell, E Yvonne Jones, Lars Fugger Nat Immunol 2002 topics set
Induction of DNA polymerase beta-dependent base excision repair in response to oxidative stress in vivo. Diane C Cabelof, Julian J Raffoul, Sunitha Yanamadala, ZhongMao Guo, Ahmad R Heydari Carcinogenesis 2002 new
Translesion replication of benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyadenosine and deoxyguanosine by human DNA polymerase iota. Ekaterina G Frank, Jane M Sayer, Heiko Kroth, Eiji Ohashi, Haruo Ohmori, Donald M Jerina, Roger Woodgate Nucleic acids research 2002 pols set
Cellular roles of DNA polymerase zeta and Rev1 protein. Christopher W Lawrence DNA repair 2002 new
The fifth essential DNA polymerase phi in Saccharomyces cerevisiae is localized to the nucleolus and plays an important role in synthesis of rRNA. Kikuo Shimizu, Yasuo Kawasaki, Shin-Ichiro Hiraga, Maki Tawaramoto, Naomi Nakashima, Akio Sugino Proceedings of the National Academy of Sciences of the United States of America 2002 new
Efficiency of correct nucleotide insertion governs DNA polymerase fidelity. William A Beard, David D Shock, Brian J Vande Berg, Samuel H Wilson The Journal of biological chemistry 2002 topics set
Effects of benzo[a]pyrene adduct stereochemistry on downstream DNA replication in vitro: evidence for different adduct conformations within the active site of DNA polymerase I (Klenow fragment). Yuriy O Alekseyev, Louis J Romano Biochemistry 2002 pols set
Cloning, expression, and characterization of thermostable DNA polymerase from Thermoanaerobacter yonseiensis. Dae Jin Kim, Hyeung Jin Jang, Yu Ryang Pyun, Yu Sam Kim J Biochem Mol Biol 2002 new
Complete genome structure of the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1. Yasukazu Nakamura, Takakazu Kaneko, Shusei Sato, Masahiko Ikeuchi, Hiroshi Katoh, Shigemi Sasamoto, Akiko Watanabe, Mayumi Iriguchi, Kumiko Kawashima, Takaharu Kimura, Yoshie Kishida, Chiaki Kiyokawa, Mitsuyo Kohara, Midori Matsumoto, Ai Matsuno, Naomi Nakazaki, Sayaka Shimpo, Masako Sugimoto, Chie Takeuchi, Masami Yamada, Satoshi Tabata DNA research : an international journal for rapid publication of reports on genes and genomes 2002 new
The difference in the stimulation by putrescine of DNA synthesis using DNA polymerase extracts of normal rat liver or of tumour tissue or host liver from tumour-bearing rats. Takahiko Taguchi, Sumiko Kurata, Mochihiko Ohashi Cell Biochem Funct 2002 new
Determinants of DNA mismatch recognition within the polymerase domain of the Klenow fragment. Elizabeth H Z Thompson, Michael F Bailey, Edwin J C Van der Schans, Catherine M Joyce, David P Millar Biochemistry 2002 pols set
Transcriptional analysis of the DNA polymerase gene of shrimp white spot syndrome virus. Li-Li Chen, Han-Ching Wang, Chiu-Jung Huang, Shao-En Peng, Yen-Gu Chen, Shin-Jen Lin, Wei-Yu Chen, Chang-Feng Dai, Hon-Tsen Yu, Chung-Hsiung Wang, Chu-Fang Lo, Guang-Hsiung Kou Virology 2002 new
Biochemical properties of the stimulatory activity of DNA polymerase alpha by the hyper-phosphorylated retinoblastoma protein. Masaharu Takemura Biochimica et biophysica acta 2002 new
Molecular mechanisms of resistance to human immunodeficiency virus type 1 with reverse transcriptase mutations K65R and K65R+M184V and their effects on enzyme function and viral replication capacity. Kirsten L White, Nicolas A Margot, Terri Wrin, Christos J Petropoulos, Michael D Miller, Lisa K Naeger Antimicrob Agents Chemother 2002 topics set
Localisation of human DNA polymerase kappa to replication foci. Valérie Bergoglio, Clarisse Bavoux, Vincent Verbiest, Jean-Sébastien Hoffmann, Christophe Cazaux J Cell Sci 2002 pols set
Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells. Patricia L Kannouche, Antonio R Fernández de Henestrosa, Barry Coull, Antonio E Vidal, Colin Gray, Daniel Zicha, Roger Woodgate, Alan R Lehmann The EMBO journal 2002 new
A role for DNA polymerase beta in mutagenic UV lesion bypass. Laurence Servant, Christophe Cazaux, Anne Bieth, Shigenori Iwai, Fumio Hanaoka, Jean-Sébastien Hoffmann The Journal of biological chemistry 2002 new
8-(Hydroxymethyl)-3,N(4)-etheno-C, a potential carcinogenic glycidaldehyde product, miscodes in vitro using mammalian DNA polymerases. B Singer, Michael Medina, Yongqing Zhang, Zhengqiang Wang, Anton B Guliaev, Bo Hang Biochemistry 2002 new
Perspectives on the molecular mechanism of inhibition and toxicity of nucleoside analogs that target HIV-1 reverse transcriptase. Karen S Anderson Biochimica et biophysica acta 2002 partial results
Activity of reverse transcriptase inhibitors in monocyte-derived dendritic cells: a possible in vitro model for postexposure prophylaxis of sexual HIV transmission. Yven Van Herrewege, Lieve Penne, Chris Vereecken, Katrien Fransen, Guido van der Groen, Luc Kestens, Jan Balzarini, Guido Vanham AIDS research and human retroviruses 2002 pols set
Genotypic and phenotypic analysis of a novel 15-base insertion occurring between codons 69 and 70 of HIV type 1 reverse transcriptase. Robert L Lobato, Eun-Young Kim, Ronald M Kagan, Thomas C Merigan AIDS research and human retroviruses 2002 pols set
Mutational analysis of Tyr-501 of HIV-1 reverse transcriptase. Effects on ribonuclease H activity and inhibition of this activity by N-acylhydrazones. Dominique Arion, Nicolas Sluis-Cremer, Kyung-Lyum Min, Michael E Abram, Ronald S Fletcher, Michael A. Parniak The Journal of biological chemistry 2002 new
Local deformations revealed by dynamics simulations of DNA polymerase Beta with DNA mismatches at the primer terminus. Linjing Yang, William A Beard, Samuel H Wilson, Benoit Roux, Suse Broyde, Tamar Schlick Journal of molecular biology 2002 new
The product of Saccharomyces cerevisiae WHIP/MGS1, a gene related to replication factor C genes, interacts functionally with DNA polymerase delta. Dana Branzei, Masayuki Seki, F Onoda, Takemi Enomoto Mol Genet Genomics 2002 new
Over-expression of human DNA polymerase lambda in E. coli and characterization of the recombinant enzyme. Noriko Shimazaki, Kenta Yoshida, Toshiko Kobayashi, Shingo Toji, Katsuyuki Tamai, Osamu Koiwai Genes to cells : devoted to molecular & cellular mechanisms 2002 partial results
RNA determinants of translational operator recognition by the DNA polymerases of bacteriophages T4 and RB69. Vasiliy M Petrov, Jim D Karam Nucleic acids research 2002 complete
Acetylation regulates the DNA end-trimming activity of DNA polymerase beta. Sameez Hasan, Nazim El-Andaloussi, Ulrike Hardeland, Paul O Hassa, Christine Bürki, Ralph Imhof, Primo Schär, Michael O Hottiger Molecular cell 2002 new
Nonradioactive detection of retroviral-associated RNase H activity in a microplate-based, high-throughput format. N McLellan, Xin Wei, Bruno Marchand, Mark A. Wainberg, Matthias Götte BioTechniques 2002 pols set
Response of human REV1 to different DNA damage: preferential dCMP insertion opposite the lesion. Yongqing Zhang, Xiaoming Wu, Olga Rechkoblit, Nicholas E Geacintov, John-Stephen Taylor, Zhengqiang Wang Nucleic acids research 2002 new
Requirement of RAD5 and MMS2 for postreplication repair of UV-damaged DNA in Saccharomyces cerevisiae. Carlos A Torres-Ramos, Satya Prakash, Louise Prakash Molecular and cellular biology 2002 new
The M184V mutation in HIV-1 reverse transcriptase reduces the restoration of wild-type replication by attenuated viruses. Xin Wei, Chen Liang, Matthias Götte, Mark A. Wainberg AIDS (London, England) 2002 pols set
The property of DNA polymerase zeta: REV7 is a putative protein involved in translesion DNA synthesis and cell cycle control. Yoshiki Murakumo Mutation research 2002 new
The absence of Mth1 inactivation and DNA polymerase kappa overexpression in rat mammary carcinomas with frequent A:T to C:G transversions. Eriko Okochi, Shizue Ichimura, Takashi Sugimura, Toshikazu Ushijima Jpn J Cancer Res 2002 new
[DNA polymerase eta: from a DNA repair-deficient genetic disease to the discovery of a novel DNA polymerase]. Fumio Hanaoka, Chikahide Masutani Seikagaku 2002 new
Role of the p68 subunit of human DNA polymerase alpha-primase in simian virus 40 DNA replication. Robert D Ott, Christoph Rehfuess, Vladimir N Podust, Jill E Clark, Ellen Fanning Molecular and cellular biology 2002 pols set
Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA. Stefan G Sarafianos, Arthur D Clark, Kalyan Das, Steve Tuske, Jens J Birktoft, Palanichamy Ilankumaran, Andagar R Ramesha, Jane M Sayer, Donald M Jerina, Paul L Boyer, Stephen H Hughes, Edward Arnold The EMBO journal 2002 topics set
The M184V mutation reduces the selective excision of zidovudine 5'-monophosphate (AZTMP) by the reverse transcriptase of human immunodeficiency virus type 1. Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes J Virol 2002 topics set
Bacillus subtilis tau subunit of DNA polymerase III interacts with bacteriophage SPP1 replicative DNA helicase G40P. María I Martínez-Jiménez, Pablo Mesa, Juan C Alonso Nucleic acids research 2002 new
[The correcting role of autonomous 3'-->5' exonucleases in mammalian multienzyme DNA polymerase complexes]. Igor V Shevelev, N V Beliakova, T P Kravetskaia, V M Krutiakov Mol Biol (Mosk) 2002 new
Structure-based interpretation of missense mutations in Y-family DNA polymerases and their implications for polymerase function and lesion bypass. François Boudsocq, Hong Ling, Wei Wen Yang, Roger Woodgate DNA repair 2002 topics set
Stimulation of DNA synthesis activity of human DNA polymerase kappa by PCNA. Lajos Haracska, Ildiko Unk, Robert E Johnson, Barbara B Phillips, Jerard Hurwitz, Louise Prakash, Satya Prakash Molecular and cellular biology 2002 pols set
A highly conserved lysine residue in phi29 DNA polymerase is important for correct binding of the templating nucleotide during initiation of phi29 DNA replication. Verónica Truniger, José María Lázaro, Luis Blanco, Margarita Salas Journal of molecular biology 2002 pols set
HIV-1: a case of RT67 deletion in a multi-treated non responder patient. R Masciari, L Cosco, M C Diaco, Dora N Della, T Ferraro, T Raimondi, B Ruperti, E Santandrea The new microbiologica 2002 pols set
DNA polymerase III holoenzyme from Thermus thermophilus identification, expression, purification of components, and use to reconstitute a processive replicase. James M Bullard, Jennifer C Williams, Wendy K Acker, Carsten Jacobi, Nebojsa Janjic, Charles S McHenry The Journal of biological chemistry 2002 partial results
Distinct and opposite diversifying activities of terminal transferase splice variants. To-Ha Thai, Mary M Purugganan, David B Roth, John F Kearney Nature immunology 2002 partial results
Differential minor groove interactions between DNA polymerase and sugar backbone of primer and template strands. Daniel Summerer, Andreas Marx Journal of the American Chemical Society 2002 new
Lysine 152 of MuLV reverse transcriptase is required for the integrity of the active site. Qingli Shi, Kamalendra Singh, Aashish Srivastava, Neerja Kaushik, Mukund J Modak Biochemistry 2002 pols set
Yeast Rev1 protein is a G template-specific DNA polymerase. Lajos Haracska, Satya Prakash, Louise Prakash The Journal of biological chemistry 2002 new
Novel phenalenone derivatives from a marine-derived fungus exhibit distinct inhibition spectra against eukaryotic DNA polymerases. Marinela Perpelescu, Jun'ichi Kobayashi, Miho Furuta, Yasutomo Ito, Shunji Izuta, Masaharu Takemura, Motoshi Suzuki, Shonen Yoshida Biochemistry 2002 pols set
Lesion bypass activities of human DNA polymerase mu. Yongqing Zhang, Xiaoming Wu, Dongyu Guo, Olga Rechkoblit, John-Stephen Taylor, Nicholas E Geacintov, Zhengqiang Wang The Journal of biological chemistry 2002 pols set
Binary system for selective photoaffinity labeling of base excision repair DNA polymerases. Olga I Lavrik, Dmitry M Kolpashchikov, Rajendra Prasad, Robert W Sobol, Samuel H Wilson Nucleic acids research 2002 new
Enzymatic synthesis of labeled DNA by PCR using new fluorescent thymidine nucleotide analogue and superthermophilic KOD dash DNA polymerase. Tsutomu Obayashi, Mohammed M Masud, Akiko N Ozaki, Hiroaki Ozaki, Masayasu Kuwahara, Hiroaki Sawai Bioorganic & medicinal chemistry letters 2002 new
Polymorphisms of cytotoxic T-lymphocyte (CTL) and T-helper epitopes within reverse transcriptase (RT) of HIV-1 subtype C from Ethiopia and Botswana following selection of antiretroviral drug resistance. Hugues Loemba, Bluma G Brenner, Michael A. Parniak, Shlomo Ma'ayan, Bonnie Spira, Daniela D Moisi, Maureen Oliveira, Mervi Detorio, Max Essex, Mark A. Wainberg Antiviral research 2002 pols set
Association of DNA polymerase mu (pol mu) with Ku and ligase IV: role for pol mu in end-joining double-strand break repair. Kiran N Mahajan, Stephanie A Nick McElhinny, Beverly S Mitchell, Dale A Ramsden Molecular and cellular biology 2002 pols set
Co-receptor usage and HIV-1 intra-clade C polymorphisms in the protease and reverse transcriptase genes of HIV-1 isolates from Ethiopia and Botswana. Hugues Loemba, Bluma G Brenner, Michael A. Parniak, Shlomo Ma'ayan, Bonnie Spira, Daniela D Moisi, Maureen Oliveira, Mervi Detorio, Max Essex, Mark A. Wainberg Antiviral therapy 2002 pols set
Acyclic and dideoxy terminator preferences denote divergent sugar recognition by archaeon and Taq DNA polymerases. Andrew F Gardner, William E Jack Nucleic acids research 2002 topics set
1H, 13C and 15N resonance assignments for the perdeuterated 22 kD palm-thumb domain of DNA polymerase beta. Michael R Gryk, Mark W Maciejewski, Anthony Robertson, Mary A Mullen, Samuel H Wilson, Gregory P Mullen J Biomol NMR 2002 new
Low expression of DNA polymerase beta in human testicular germ cell tumours--impact on foetal gonocytic origin theory. Radosława Nowak, Ewa A Grzybowska, Anna Wilczyńska, Roman Pykało, Janusz A Siedlecki Acta Oncol 2002 new
[DNA polymerase delta]. Toshiki Tsurimoto Seikagaku 2002 new
Fidelity of DNA polymerase epsilon holoenzyme from budding yeast Saccharomyces cerevisiae. Kikuo Shimizu, Keiji Hashimoto, Jake M Kirchner, Wataru Nakai, Hiroko Nishikawa, Michael A Resnick, Akio Sugino The Journal of biological chemistry 2002 new
Active site mutation in DNA polymerase gamma associated with progressive external ophthalmoplegia causes error-prone DNA synthesis. Mikhail V Ponamarev, Matthew J Longley, Dinh Nguyen, Thomas A Kunkel, William C Copeland The Journal of biological chemistry 2002 pols set
DNA polymerase III from Escherichia coli cells expressing mutA mistranslator tRNA is error-prone. Abu Amar M Al Mamun, Kenneth J Marians, M Zafri Humayun The Journal of biological chemistry 2002 pols set
Efficiency, specificity and DNA polymerase-dependence of translesion replication across the oxidative DNA lesion 8-oxoguanine in human cells. Sharon Avkin, Zvi Livneh Mutation research 2002 new
High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading. Robert E Goldsby, Laura E Hays, Xinbin Chen, Elise A Olmsted, William B Slayton, Gerry J Spangrude, Bradley D Preston Proceedings of the National Academy of Sciences of the United States of America 2002 new
Genetic divergence of human immunodeficiency virus type 1 Ethiopian clade C reverse transcriptase (RT) and rapid development of resistance against nonnucleoside inhibitors of RT. Hugues Loemba, Bluma G Brenner, Michael A. Parniak, Shlomo Ma'ayan, Bonnie Spira, Daniela D Moisi, Maureen Oliveira, Mervi Detorio, Mark A. Wainberg Antimicrobial agents and chemotherapy 2002 new
Mutations of mitochondrial DNA polymerase gammaA are a frequent cause of autosomal dominant or recessive progressive external ophthalmoplegia. Eleonora Lamantea, Valeria Tiranti, Andreina Bordoni, Antonio Toscano, Francesco Bono, Serena Servidei, Alex Papadimitriou, Hans Spelbrink, Laura Silvestri, Giorgio Casari, Giacomo P Comi, Massimo Zeviani Annals of neurology 2002 pols set
Development of a monoclonal antibody for neutralization of human telomerase activity. Junmei Wang, Bo Zhang, Shaomin Yang, Xiaohui He, Jisheng Han, Bingsi Li, Lin Hou Hybridoma and hybridomics 2002 new
DNA polymerase kappa deficiency does not affect somatic hypermutation in mice. Dominik Schenten, Valerie L Gerlach, Caixia Guo, Susana Velasco-Miguel, Christa L Hladik, Charles L White, Errol C Friedberg, Klaus Rajewsky, Gloria Esposito Eur J Immunol 2002 new
Prevalence of the mutational pattern E44D/A and/or V118I in the reverse transcriptase (RT) gene of HIV-1 in relation to treatment with nucleoside analogue RT inhibitors. Brigitte Montes, Michel Segondy Journal of medical virology 2002 pols set
Importance of compartment formation for a self-encoding system. Tomoaki Matsuura, Masamitsu Yamaguchi, Elizabeth P Ko-Mitamura, Yasufumi Shima, Itaru Urabe, Tetsuya Yomo Proceedings of the National Academy of Sciences of the United States of America 2002 pols set
Persistence and fitness of multidrug-resistant human immunodeficiency virus type 1 acquired in primary infection. Bluma G Brenner, Jean-Pierre Routy, Marco Petrella, Daniela D Moisi, Maureen Oliveira, Mervi Detorio, Bonnie Spira, Vidal Essabag, Brian Conway, Richard G Lalonde, Rafick-Pierre Sekaly, Mark A. Wainberg Journal of virology 2002 new
Specialized DNA polymerases, cellular survival, and the genesis of mutations. Errol C Friedberg, Robert Wagner, Miroslav Radman Science 2002 topics set
The 3' 5' exonucleases. Igor V Shevelev, Ulrich Hübscher Nature reviews. Molecular cell biology 2002 topics set
Characterization of DNA synthesis catalyzed by bacteriophage T4 replication complexes reconstituted on synthetic circular substrates. Farid A Kadyrov, John W Drake Nucleic acids research 2002 complete
Synthesis of taurospongin A: a potent inhibitor of DNA polymerase and HIV reverse transcriptase, using pi-allyltricarbonyliron lactone complexes. Christopher J Hollowood, Steven V Ley, Shigeo Yamanoi Chem Commun (Camb) 2002 new
Synthesis of 3' '-substituted TSAO derivatives with anti-HIV-1 and anti-HIV-2 activity through an efficient palladium-catalyzed cross-coupling approach. Esther Lobatón, Fátima Rodríguez-Barrios, Federico Gago, María-Jesús Pérez-Pérez, Erik De Clercq, Jan Balzarini, María-José Camarasa, Sonsoles Velázquez Journal of medicinal chemistry 2002 pols set
The Tat protein of human immunodeficiency virus type 1 (HIV-1) can promote placement of tRNA primer onto viral RNA and suppress later DNA polymerization in HIV-1 reverse transcription. Masanori Kameoka, Max Morgan, Marc Binette, Rodney S Russell, Liwei Rong, Xiaofeng Guo, Andrew Mouland, Lawrence Kleiman, Chen Liang, Mark A. Wainberg Journal of virology 2002 new
Chemotherapy of varicella-zoster virus by a novel class of highly specific anti-VZV bicyclic pyrimidine nucleosides. Jan Balzarini, Christopher McGuigan Biochimica et biophysica acta 2002 new
Combinations against combinations: associations of anti-HIV 1 reverse transcriptase drugs challenged by constellations of drug resistance mutations. Giovanni Maga, Silvio Spadari Current drug metabolism 2002 pols set
3'-5' exonuclease of Klenow fragment: role of amino acid residues within the single-stranded DNA binding region in exonucleolysis and duplex DNA melting. Wai-Chung Lam, Elizabeth H Z Thompson, Olga Potapova, Xiaojun Chen Sun, Catherine M Joyce, David P Millar Biochemistry 2002 partial results
Exploring the effects of active site constraints on HIV-1 reverse transcriptase DNA polymerase fidelity. Janina Cramer, Michael Strerath, Andreas Marx, Tobias Restle The Journal of biological chemistry 2002 partial results
Family growth: the eukaryotic DNA polymerase revolution. Katarzyna Bebenek, Thomas A Kunkel Cell Mol Life Sci 2002 new
Structural and functional properties of the HIV-1 RNA-tRNA(Lys)3 primer complex annealed by the nucleocapsid protein: comparison with the heat-annealed complex. Fabienne Brulé, Roland Marquet, Liwei Rong, Mark A. Wainberg, Bernard P Roques, Stuart F J Le Grice, Bernard Ehresmann, Chantal Ehresmann RNA (New York, N.Y.) 2002 pols set
Error-prone repair DNA polymerases in prokaryotes and eukaryotes. Myron F Goodman Annu Rev Biochem 2002 new
Analysis of a multicomponent thermostable DNA polymerase III replicase from an extreme thermophile. Irina Bruck, Alexander Yuzhakov, Olga Yurieva, David Jeruzalmi, Maija Skangalis, John Kuriyan, Mike E O'Donnell The Journal of biological chemistry 2002 new
Tamoxifen regulates human telomerase reverse transcriptase (hTERT) gene expression differently in breast and endometrial cancer cells. Zhengqiang Wang, Satoru Kyo, Yoshiko Maida, Masahiro Takakura, Masaaki Tanaka, Noriyuki Yatabe, Taro Kanaya, Mitsuhiro Nakamura, Koji Koike, Koji Hisamoto, Masahide Ohmichi, Masaki Inoue Oncogene 2002 new
Clamp loaders and sliding clamps. David Jeruzalmi, Mike E O'Donnell, John Kuriyan Current opinion in structural biology 2002 topics set
Resolving a fidelity paradox: why Escherichia coli DNA polymerase II makes more base substitution errors in AT- compared with GC-rich DNA. Zhengqiang Wang, Eli Lazarov, Mike E O'Donnell, Myron F Goodman The Journal of biological chemistry 2002 pols set
Effect of the O6 substituent on misincorporation kinetics catalyzed by DNA polymerases at O(6)-methylguanine and O(6)-benzylguanine. Adrienne M Woodside, F Peter Guengerich Biochemistry 2002 pols set
[Osteogenic potential of fibroblasts with reconstituted telomerase activity]. Zhengqiang Wang, Yingqian Li, You-ming Zhu Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 2002 new
Synthesis of new modified DNAs by hyperthermophilic DNA polymerase: substrate and template specificity of functionalized thymidine analogues bearing an sp3-hybridized carbon at the C5 alpha-position for several DNA polymerases. Hiroki Sawai, Akiko Ozaki-Nakamura, Masayuki Mine, Hiroaki Ozaki Bioconjug Chem 2002 new
Human telomerase accelerates growth of lens epithelial cells through regulation of the genes mediating RB/E2F pathway. Hua Xiang, Juan Wang, Yingwei Mao, Mingyao Liu, Venkat N Reddy, David Wan-Cheng Li Oncogene 2002 new
Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and its complexes with ATP or CTP. Fang Li, Yong Xiong, Jianhong Wang, HyunDae D Cho, Kozo Tomita, Alan M Weiner, Thomas A Steitz Cell 2002 new
[The advance of tumor development mechanism applying mTR-/- mouse model]. Peng Li, Dong-Lin Wu, He-Wen Ma, Huan-Min Yang, Yu-Jing Zhang Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji 2002 new
Effect of manganese on in vitro replication of damaged DNA catalyzed by the herpes simplex virus type-1 DNA polymerase. Giuseppe Villani, Nicolas Tanguy Le Gac, Luc Wasungu, Dominique Y Burnouf, Robert P P Fuchs, Paul E Boehmer Nucleic acids research 2002 topics set
Macrophages and HIV infection: therapeutical approaches toward this strategic virus reservoir. Stefano Aquaro, Raffaele Caliò, Jan Balzarini, Maria Concetta Bellocchi, Enrico Garaci, CF Perno Antiviral research 2002 pols set
A three-domain structure for the delta subunit of the DNA polymerase III holoenzyme delta domain III binds delta' and assembles into the DnaX complex. James M Bullard, Arthur E Pritchard, Min-Sun Song, Bradley P Glover, Anna Wieczorek, Joe Chen, Nebojsa Janjic, Charles S McHenry The Journal of biological chemistry 2002 new
Correlation of somatic hypermutation specificity and A-T base pair substitution errors by DNA polymerase eta during copying of a mouse immunoglobulin kappa light chain transgene. Youri I Pavlov, Igor B Rogozin, Alexey P Galkin, Anna Y Aksenova, Fumio Hanaoka, Christina Rada, Thomas A Kunkel Proceedings of the National Academy of Sciences of the United States of America 2002 pols set
Destabilization of the HIV-1 reverse transcriptase dimer upon interaction with N-acyl hydrazone inhibitors. Nicolas Sluis-Cremer, Dominique Arion, Michael A. Parniak Molecular pharmacology 2002 pols set
Base composition at mtDNA boundaries suggests a DNA triple helix model for human mitochondrial DNA large-scale rearrangements. Christophe Rocher, Thierry Letellier, William C Copeland, Patrick Lestienne Molecular genetics and metabolism 2002 pols set
Varied DNA polymerase-substrate interactions in the nucleotide binding pocket. Michael Strerath, Daniel Summerer, Andreas Marx Chembiochem 2002 new
New developments in anti-HIV chemotherapy. Erik De Clercq Biochimica et biophysica acta 2002 pols set
HIV-1 drug resistance: can we overcome? Bluma G Brenner, Dan Turner, Mark A. Wainberg Expert opinion on biological therapy 2002 pols set
The M184V mutation in reverse transcriptase can delay reversion of attenuated variants of simian immunodeficiency virus. James B Whitney, Maureen Oliveira, Mervi Detorio, Yongjun Guan, Mark A. Wainberg Journal of virology 2002 new
New structural and mechanistic insight into the A-rule and the instructional and non-instructional behavior of DNA photoproducts and other lesions. John-Stephen Taylor Mutation research 2002 topics set
A nuclear 3'-5' exonuclease proofreads for the exonuclease-deficient DNA polymerase alpha. Kevin R Brown, Krista L Weatherdon, Carole L Galligan, Violetta Skalski DNA repair 2002 new
New light-sensitive nucleosides for caged DNA strand breaks. Adrian Dussy, Christoph Meyer, Edith Quennet, Thomas A Bickle, Bernd Giese, Andreas Marx Chembiochem : a European journal of chemical biology 2002 new
Involvement of DNA polymerase beta in protection against the cytotoxicity of oxidative DNA damage. Julie K Horton, Audrey Baker, Brian J Vande Berg, Robert W Sobol, Samuel H Wilson DNA repair 2002 new
Heterogeneity in expression of DNA polymerase beta and DNA repair activity in human tumor cell lines. Nandan Bhattacharyya, Huan-Chao Chen, Liming Wang, Sanjeev Banerjee Gene Expr 2002 new
In vivo reconstitution of Saccharomyces cerevisiae DNA polymerase epsilon in insect cells. Purification and characterization. Rajiv Dua, Daniel L Levy, Caroline M Li, Peter M Snow, Judith L Campbell The Journal of biological chemistry 2002 pols set
Structure-function relationship of synthetic sulfoquinovosyl-acylglycerols as mammalian DNA polymerase inhibitors. Chikako Murakami, Takayuki Yamazaki, Shinya Hanashima, Shunya Takahashi, Keisuke Ohta, Hiromi Yoshida, Fumio Sugawara, Kengo Sakaguchi, Yoshiyuki Mizushina Arch Biochem Biophys 2002 pols set
HIV mutagenesis and the evolution of antiretroviral drug resistance. Louis M Mansky Drug Resist Updat 2002 topics set
Mapping of the interaction interface of DNA polymerase beta with XRCC1. Michael R Gryk, Assen Marintchev, Mark W Maciejewski, Anthony Robertson, Samuel H Wilson, Gregory P Mullen Structure (London, England : 1993) 2002 new
Escherichia coli DNA polymerase III can replicate efficiently past a T-T cis-syn cyclobutane dimer if DNA polymerase V and the 3' to 5' exonuclease proofreading function encoded by dnaQ are inactivated. Angela Borden, Paul I O'Grady, Dominique Vandewiele, Antonio R Fernández de Henestrosa, Christopher W Lawrence, Roger Woodgate Journal of bacteriology 2002 complete Christopher W Lawrence*
The TREX2 3'-->5' exonuclease physically interacts with DNA polymerase delta and increases its accuracy. Igor V Shevelev, Kristijan Ramadan, Ulrich Hübscher ScientificWorldJournal 2002 new
Threonine 79 is a hinge residue that governs the fidelity of DNA polymerase beta by helping to position the DNA within the active site. Mausumi Maitra, Andrew Gudzelak, Shu-Xia Li, Yoshihiro Matsumoto, Kristin A Eckert, Joachim Jager, Joann B Sweasy The Journal of biological chemistry 2002 new
Benzo[a]pyrene diol epoxide-deoxyguanosine adducts are accurately bypassed by yeast DNA polymerase zeta in vitro. Srilatha Simhadri, Pavel Kramata, Barbara Zajc, Jane M Sayer, Donald M Jerina, David C Hinkle, Caroline S-J Wei Mutation research 2002 new
Sequence changes in the human adenovirus type 5 DNA polymerase associated with resistance to the broad spectrum antiviral cidofovir. Paul R Kinchington, Trinita Araullo-Cruz, Jean-Paul Vergnes, Kathleen Yates, Y Jerold Gordon Antiviral Res 2002 new
Catalyzing "hot" reactions: enzymes from hyperthermophilic Archaea. Tadayuki Imanaka, Haruyuki Atomi Chemical record (New York, N.Y.) 2002 partial results
Novel anti-inflammatory compounds from Rubus sieboldii, triterpenoids, are inhibitors of mammalian DNA polymerases. Chikako Murakami, Kiyomi Ishijima, Mitsuru Hirota, Kengo Sakaguchi, Hiromi Yoshida, Yoshiyuki Mizushina Biochimica et biophysica acta 2002 new
Increase in DNA polymerase gamma in the hearts of adriamycin-administered rats. Mari Ogihara, Munehiko Tanno, Naotaka Izumiyama, Hiroaki Nakamura, Takahiko Taguchi Exp Mol Pathol 2002 new
Altering the RNase H primer grip of human immunodeficiency virus reverse transcriptase modifies cleavage specificity. Jason W Rausch, Daniela Lener, Jennifer T Miller, John G Julias, Stephen H Hughes, Stuart F J Le Grice Biochemistry 2002 pols set
Metabolic activation of nucleoside and nucleotide reverse transcriptase inhibitors in dendritic and Langerhans cells. Jan Balzarini, Yven Van Herrewege, Guido Vanham AIDS (London, England) 2002 new
Analysis of the stimulation of DNA polymerase V of Escherichia coli by processivity proteins. Ayelet Maor-Shoshani, Zvi Livneh Biochemistry 2002 pols set
GC-rich template amplification by inverse PCR. DNA polymerase and solvent effects. Alain Moreau, Da Shen Wang, Steve Forget, Colette Duez, Jean Dusart Methods in molecular biology (Clifton, N.J.) 2002 new
DNA-polymerase alpha, beta, delta and epsilon activities in isolated neuronal and astroglial cell fractions from developing and aging rat cerebral cortex. N S Raji, T Hari Krishna, Kalluri Subba Rao Int J Dev Neurosci 2002 new
The mitochondrial DNA polymerase as a target of oxidative damage. Maria A Graziewicz, Brian J Day, William C Copeland Nucleic acids research 2002 new
Deregulated DNA polymerase beta induces chromosome instability and tumorigenesis. Valérie Bergoglio, Marie-Jeanne Pillaire, Magali Lacroix-Triki, Brigitte Raynaud-Messina, Yvan Canitrot, Anne Bieth, Michèle Garès, Michel Wright, Georges Delsol, Lawrence A Loeb, Christophe Cazaux, Jean-Sébastien Hoffmann Cancer research 2002 new
Replication fork reversal in DNA polymerase III mutants of Escherichia coli: a role for the beta clamp. Gianfranco Grompone, Marie Seigneur, S Dusko Ehrlich, Bénédicte Michel Molecular microbiology 2002 pols set
Base excision repair of adenine/8-oxoguanine mispairs by an aphidicolin-sensitive DNA polymerase in human cell extracts. Eleonora Parlanti, Paola Fortini, Peter Macpherson, Jacques Laval, Eugenia Dogliotti Oncogene 2002 new
[Structural homology between molecular probes binding site of DNA polymerase beta and DNA topoisomerase II]. Yoshiyuki Mizushina, Nobuyuki Kasai, Fumio Sugawara, Kengo Sakaguchi Tanpakushitsu Kakusan Koso 2002 new
Weak strand displacement activity enables human DNA polymerase beta to expand CAG/CTG triplet repeats at strand breaks. Michael J Hartenstine, Myron F Goodman, John Petruska The Journal of biological chemistry 2002 pols set
DNA polymerase I of Mycobacterium tuberculosis: functional role of a conserved aspartate in the hinge joining the M and N helices. Cindy Jo Arrigo, Kamalendra Singh, Mukund J Modak The Journal of biological chemistry 2002 pols set
Hyper-processive and slower DNA chain elongation catalysed by DNA polymerase III holoenzyme purified from the dnaE173 mutator mutant of Escherichia coli. Yutaka Sugaya, Keiichi Ihara, Yuji Masuda, Eiichi Ohtsubo, Hisaji Maki Genes Cells 2002 pols set
Direct interaction between mammalian DNA polymerase beta and proliferating cell nuclear antigen. Padmini S Kedar, Soon-Jong Kim, Anthony Robertson, Esther W Hou, Rajendra Prasad, Julie K Horton, Samuel H Wilson The Journal of biological chemistry 2002 pols set
Deficiency in DNA polymerase beta provokes replication-dependent apoptosis via DNA breakage, Bcl-2 decline and caspase-3/9 activation. Kirsten Ochs, Jochen Lips, Simone Profittlich, Bernd Kaina Cancer research 2002 new
Suppression of Saccharomyces cerevisiae rad27 null mutant phenotypes by the 5' nuclease domain of Escherichia coli DNA polymerase I. Xuemin Sun, Phillis Wu, Li Zheng, Douglas Thrower, Arthur Partikian, Junzhuan Qiu, Binghui Shen Curr Genet 2002 pols set
Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision. Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes J Virol 2002 topics set
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. George Adrian Calin, Calin Dan Dumitru, Masayoshi Shimizu, Roberta Bichi, Simona Zupo, Evan Noch, Hansjuerg Aldler, Sashi Rattan, Michael Keating, Kanti Rai, Laura Rassenti, Thomas Kipps, Massimo Negrini, Florencia Bullrich, Carlo M Croce Proceedings of the National Academy of Sciences of the United States of America 2002 new
Evolution of DNA polymerase families: evidences for multiple gene exchange between cellular and viral proteins. Jonathan Filée, Patrick Forterre, Tang Sen-Lin, Jacqueline Laurent J Mol Evol 2002 new
Phosphorylation of the Epstein-Barr virus (EBV) DNA polymerase processivity factor EA-D by the EBV-encoded protein kinase and effects of the L-riboside benzimidazole 1263W94. Edward Gershburg, Joseph S Pagano J Virol 2002 pols set
Lagging strand synthesis in coordinated DNA synthesis by bacteriophage t7 replication proteins. Joonsoo Lee, Paul D Chastain, Jack D Griffith, Charles C Richardson Journal of molecular biology 2002 pols set
Posttranslational modification of the umuD-encoded subunit of Escherichia coli DNA polymerase V regulates its interactions with the beta processivity clamp. Mark D Sutton, Issay Narumi, Graham C Walker Proceedings of the National Academy of Sciences of the United States of America 2002 pols set
Essential amino acid residues in the single-stranded DNA-binding protein of bacteriophage T7. Identification of the dimer interface. Lisa F Rezende, Thomas Hollis, Tom Ellenberger, Charles C Richardson The Journal of biological chemistry 2002 pols set
Positive and negative effects of deletions and mutations within the 5' flanking sequences of Plasmodium falciparum DNA polymerase delta. Megan E Porter Mol Biochem Parasitol 2002 new
Three-dimensional structural model analysis of the binding site of an inhibitor, nervonic acid, of both DNA polymerase beta and HIV-1 reverse transcriptase. Nobuyuki Kasai, Yoshiyuki Mizushina, Fumio Sugawara, Kengo Sakaguchi Journal of biochemistry 2002 pols set
D-loop mutations in mitochondrial DNA: link with mitochondrial DNA depletion? Cyrille Barthélémy, Hélène Ogier de Baulny, Anne Lombès Human genetics 2002 pols set
Human DINB1-encoded DNA polymerase kappa is a promiscuous extender of mispaired primer termini. M Todd Washington, Robert E Johnson, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2002 topics set
Thermostable DNA polymerase from the archaeon Archaeoglobus fulgidus. S E Chalov, O L Voronina, O V Sergienko, V G Lunin Dokl Biochem Biophys 2002 new
DNA polymerase lambda from calf thymus preferentially replicates damaged DNA. Kristijan Ramadan, Igor V Shevelev, Giovanni Maga, Ulrich Hübscher The Journal of biological chemistry 2002 new
Preferential misincorporation of purine nucleotides by human DNA polymerase eta opposite benzo[a]pyrene 7,8-diol 9,10-epoxide deoxyguanosine adducts. Dominic Chiapperino, Heiko Kroth, Irene H Kramarczuk, Jane M Sayer, Chikahide Masutani, Fumio Hanaoka, Donald M Jerina, Albert M Cheh The Journal of biological chemistry 2002 pols set
Sequence analysis and phenotypes of five temperature sensitive mutator alleles of dnaE, encoding modified alpha-catalytic subunits of Escherichia coli DNA polymerase III holoenzyme. Dominique Vandewiele, Antonio R Fernández de Henestrosa, Andrew R Timms, Bryn A Bridges, Roger Woodgate Mutation research 2002 pols set
WRN helicase accelerates the transcription of ribosomal RNA as a component of an RNA polymerase I-associated complex. Miwa Shiratori, Takahisa Suzuki, Chie Itoh, Makoto Goto, Yasuhiro Furuichi, Takehisa Matsumoto Oncogene 2002 new
The DNA polymerase domain of pol(epsilon) is required for rapid, efficient, and highly accurate chromosomal DNA replication, telomere length maintenance, and normal cell senescence in Saccharomyces cerevisiae. Tomoko Ohya, Yasuo Kawasaki, Shin-Ichiro Hiraga, Sakie Kanbara, Kou Nakajo, Naomi Nakashima, Akiko Suzuki, Akio Sugino The Journal of biological chemistry 2002 new
The mutational specificity of the Dbh lesion bypass polymerase and its implications. Olga Potapova, Nigel D F Grindley, Catherine M Joyce The Journal of biological chemistry 2002 partial results
A positively charged residue of phi29 DNA polymerase, highly conserved in DNA polymerases from families A and B, is involved in binding the incoming nucleotide. Verónica Truniger, José María Lázaro, Francisco J Esteban, Luis Blanco, Margarita Salas Nucleic acids research 2002 pols set
Template-directed dye-terminator incorporation with fluorescence polarization detection for analysis of single nucleotide polymorphisms implicated in sepsis. Bradley D Freeman, Timothy G Buchman, Sean McGrath, Arash Rafii Tabrizi, Barbara A Zehnbauer J Mol Diagn 2002 topics set
A 70-kDa chloroplast DNA polymerase from pea ( Pisum sativum) that shows high processivity and displays moderate fidelity. A Gaikwad, D V Hop, Sunil K Mukherjee Mol Genet Genomics 2002 new
The influence of the Cdc27 subunit on the properties of the Schizosaccharomyces pombe DNA polymerase delta. Vladimir P Bermudez, Stuart A MacNeill, Inger Tappin, Jerard Hurwitz The Journal of biological chemistry 2002 new
Mutations in the hepatitis B virus preS2 region and abrogated receptor activity for polymerized human albumin. Junichi Kondo, Hiroyuki Shimomura, Shin-ichi Fujioka, Yoshiaki Iwasaki, Shinjiro Takagi, Yasuhiro Ohnishi, Hideyuki Tsuji, Kosaku Sakaguchi, Kazuhide Yamamoto, Takao Tsuji Acta medica Okayama 2002 new
Characterization of DNA polymerase delta from a higher plant, rice (Oryza sativa L.). Yukinobu Uchiyama, Masami Hatanaka, Seisuke Kimura, Toyotaka Ishibashi, Tadamasa Ueda, Yoshikiyo Sakakibara, Takehisa Matsumoto, Tomoyuki Furukawa, Junji Hashimoto, Kengo Sakaguchi Gene 2002 new
Reconstitution and characterization of the human DNA polymerase delta four-subunit holoenzyme. Bin Xie, Nayef Mazloum, Lingfeng Liu, Amal A Rahmeh, Hao Li, Marietta Y W T Lee Biochemistry 2002 pols set
Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors. Jingshan Ren, Louise E Bird, Phillip P Chamberlain, Guillaume B E Stewart-Jones, David I Stuart, David K Stammers Proceedings of the National Academy of Sciences of the United States of America 2002 partial results
[Experimental study of K562 cell apoptosis induced by harringtonine]. Rong Li, Xiao-li Liu, Qing-feng Du, Hong Tian, Lan-lin Song, Yongqing Zhang, Yi Yang, Shu-yun Zhou Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 2002 new
Evidence against a simple tethering model for enhancement of herpes simplex virus DNA polymerase processivity by accessory protein UL42. Murari Chaudhuri, Deborah S Parris J Virol 2002 new
The mitochondrial DNA polymerase beta from Crithidia fasciculata has 5'-deoxyribose phosphate (dRP) lyase activity but is deficient in the release of dRP. Tina T Saxowsky, Yoshihiro Matsumoto, Paul T Englund The Journal of biological chemistry 2002 new
Hormonal regulation of DNA polymerase beta activity and expression in rat adrenal glands and testes. Motoko Kotake, Akira Nakai, Akio Nagasaka, Mitsuyasu Itoh, Hiroyoshi Hidaka, Shonen Yoshida Mol Cell Endocrinol 2002 new
Characterization of an Epstein-Barr virus-related gammaherpesvirus from common marmoset (Callithrix jacchus). Hal B Jenson, Yasmin Ench, Yongqing Zhang, Shou-Jiang Gao, John R Arrand, Michael Mackett The Journal of general virology 2002 new
ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase. Lisa K Naeger, Nicolas A Margot, Michael D Miller Antimicrob Agents Chemother 2002 topics set
Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene). Naomi Suzuki, Eiji Ohashi, Alexander Kolbanovskiy, Nicholas E Geacintov, Arthur P Grollman, Haruo Ohmori, Shinya Shibutani Biochemistry 2002 pols set
Replicative enzymes and ageing: importance of DNA polymerase alpha function to the events of cellular ageing. Vinod K Srivastava, David L Busbee Ageing Res Rev 2002 new
DNA polymerase lambda, a novel DNA repair enzyme in human cells. Miguel García-Díaz, Katarzyna Bebenek, Rosario Sabariegos, Orlando Domínguez, Josana Rodríguez, Tomas Kirchhoff, Esther García-Palomero, Angel J Picher, Raquel Juárez, José F Ruiz, Thomas A Kunkel, Luis Blanco The Journal of biological chemistry 2002 partial results
A conserved Tyr residue is required for sugar selectivity in a Pol alpha DNA polymerase. Guangwei Yang, Matthew Franklin, Jinming Li, T C Lin, William H Konigsberg Biochemistry 2002 new
In vitro production and screening of DNA polymerase eta mutants for catalytic diversity. Eitan Glick, Jon P Anderson, Lawrence A Loeb BioTechniques 2002 new
Eukaryotic DNA polymerases. Ulrich Hubscher, Giovanni Maga, Silvio Spadari Annual review of biochemistry 2002 topics set
Molecular basis of fidelity of DNA synthesis and nucleotide specificity of retroviral reverse transcriptases. L Menéndez-Arias Prog Nucleic Acid Res Mol Biol 2002 pols set
Low fidelity DNA synthesis by a y family DNA polymerase due to misalignment in the active site. Robert J Kokoska, Katarzyna Bebenek, François Boudsocq, Roger Woodgate, Thomas A Kunkel The Journal of biological chemistry 2002 partial results
Importance of the N-terminal region of the phage GA-1 single-stranded DNA-binding protein for its self-interaction ability and functionality. Irene Gascón, José L Carrascosa, Laurentino Villar, José María Lázaro, Margarita Salas The Journal of biological chemistry 2002 pols set
Proofreading of DNA polymerase eta-dependent replication errors. Katarzyna Bebenek, Toshiro Matsuda, Chikahide Masutani, Fumio Hanaoka, Thomas A Kunkel The Journal of biological chemistry 2001 pols set
The delta and delta ' subunits of the DNA polymerase III holoenzyme are essential for initiation complex formation and processive elongation. Min-Sun Song, P T Pham, M Olson, J R Carter, M A Franden, Roel M Schaaper, Charles S McHenry The Journal of biological chemistry 2001 new
Identification of a mutant DNA polymerase delta in Saccharomyces cerevisiae with an antimutator phenotype for frameshift mutations. M I Hadjimarcou, Robert J Kokoska, Thomas D Petes, Linda J Reha-Krantz Genetics 2001 pols set
Long and accurate PCR with a mixture of KOD DNA polymerase and its exonuclease deficient mutant enzyme. Motomu Nishioka, H Mizuguchi, Shinsuke Fujiwara, S Komatsubara, Masao Kitabayashi, H Uemura, Masahiro Takagi, Tadayuki Imanaka J Biotechnol 2001 new
Fidelity of nucleotide insertion at 8-oxo-7,8-dihydroguanine by mammalian DNA polymerase delta. Steady-state and pre-steady-state kinetic analysis. H J Einolf, F Peter Guengerich The Journal of biological chemistry 2001 pols set
Mechanism of beta clamp opening by the delta subunit of Escherichia coli DNA polymerase III holoenzyme. Jelena Stewart, Manju M Hingorani, Zvi Kelman, Mike E O'Donnell The Journal of biological chemistry 2001 pols set
A unified nomenclature for the subunits of eukaryotic DNA polymerase delta. Stuart A MacNeill, Giuseppe Baldacci, Peter M J Burgers, Ulrich Hübscher Trends in biochemical sciences 2001 new
Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA. Stefan G Sarafianos, Kalyan Das, C Tantillo, Arthur D Clark, Jianping Ding, J M Whitcomb, Paul L Boyer, Stephen H Hughes, Edward Arnold The EMBO journal 2001 topics set
Resistance profiles to antiretroviral drugs in HIV-1 drug-naive patients in Argentina. G H Kijak, S E Pampuro, M M Avila, C Zala, P Cahn, Mark A. Wainberg, H Salomón Antiviral therapy 2001 pols set
HIV-1 nucleocapsid protein and the secondary structure of the binary complex formed between tRNA(Lys.3) and viral RNA template play different roles during initiation of (-) strand DNA reverse transcription. Liwei Rong, Chen Liang, M Hsu, Xiaofeng Guo, Bernard P Roques, Mark A. Wainberg The Journal of biological chemistry 2001 pols set
Mutator effects of overproducing DNA polymerase eta (Rad30) and its catalytically inactive variant in yeast. Youri I Pavlov, Dinh Nguyen, Thomas A Kunkel Mutation research 2001 new
Interaction of the beta sliding clamp with MutS, ligase, and DNA polymerase I. Francisco J López de Saro, Mike E O'Donnell Proceedings of the National Academy of Sciences of the United States of America 2001 new
Alkylglycerol prodrugs of phosphonoformate are potent in vitro inhibitors of nucleoside-resistant human immunodeficiency virus type 1 and select for resistance mutations that suppress zidovudine resistance. J L Hammond, D L Koontz, Holly Z Bazmi, J R Beadle, S E Hostetler, G D Kini, Kathy A Aldern, Douglas D Richman, Karl Y Hostetler, John W Mellors Antimicrob Agents Chemother 2001 topics set
Identification of crucial hydrogen-bonding residues for the interaction of herpes simplex virus DNA polymerase subunits via peptide display, mutational, and calorimetric approaches. K G Bridges, C S Chow, Donald M Coen J Virol 2001 new
DNA Polymerase Selectivity: Sugar Interactions Monitored with High-Fidelity Nucleotides This work was supported by a grant from the Deutsche Forschungsgemeinschaft. We thank Professor Dr. Michael Famulok for his continuing support. Daniel Summerer, Andreas Marx Angewandte Chemie (International ed. in English) 2001 new
Anti-HIV-1 activity of benzothiadiazine dioxide. A Martinez, C Gil, A Castro, C Perez, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Erik De Clercq Antiviral chemistry & chemotherapy 2001 pols set
Low concentration N-methyl-N'-nitro-N-nitrosoguanidine activates DNA polymerase-beta expression via cyclic-AMP-protein kinase A-cAMP response element binding protein pathway. G Wang, Y Yu, Xinbin Chen, H Xie Mutation research 2001 new
Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase. Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes J Virol 2001 topics set
RNase H cleavage of the 5' end of the human immunodeficiency virus type 1 genome. Hong Qiang Gao, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes J Virol 2001 pols set
In vivo mutagenesis by Escherichia coli DNA polymerase I. Ile(709) in motif A functions in base selection. A Shinkai, Lawrence A Loeb The Journal of biological chemistry 2001 pols set
Chromodomain protein Swi6-mediated role of DNA polymerase alpha in establishment of silencing in fission Yeast. S Ahmed, S Saini, S Arora, J Singh The Journal of biological chemistry 2001 new
Phi29 family of phages. Wilfried J J Meijer, J A Horcajadas, Margarita Salas Microbiol Mol Biol Rev 2001 pols set
Translesional synthesis on a DNA template containing N2-methyl-2'-deoxyguanosine catalyzed by the Klenow fragment of Escherichia coli DNA polymerase I. Manabu Yasui, S Matsui, M Ihara, Y R Laxmi, Shinya Shibutani, Toshiro Matsuda Nucleic acids research 2001 pols set
Translesion synthesis by yeast DNA polymerase zeta from templates containing lesions of ultraviolet radiation and acetylaminofluorene. Dongyu Guo, Xiaoming Wu, D K Rajpal, John-Stephen Taylor, Zhengqiang Wang Nucleic acids research 2001 new
Isolation of a homodimeric lectin with antifungal and antiviral activities from red kidney bean (Phaseolus vulgaris) seeds. X Y Ye, T B Ng, P W Tsang, Jianbin Wang Journal of protein chemistry 2001 new
The DNA polymerase III holoenzyme: an asymmetric dimeric replicative complex with leading and lagging strand polymerases. Bradley P Glover, Charles S McHenry Cell 2001 new
Nuclear DNA polymerase beta from Leishmania infantum. Cloning, molecular analysis and developmental regulation. S Taladriz, T Hanke, M J Ramiro, Miguel García-Díaz, M García De Lacoba, Luis Blanco, Vicente Larraga Nucleic acids research 2001 new
Defective DNA polymerase-delta proofreading causes cancer susceptibility in mice. Robert E Goldsby, Nicole A Lawrence, Laura E Hays, Elise A Olmsted, Xinbin Chen, M Singh, Bradley D Preston Nat Med 2001 new
Creating a dynamic picture of the sliding clamp during T4 DNA polymerase holoenzyme assembly by using fluorescence resonance energy transfer. Michael A Trakselis, S C Alley, E Abel-Santos, Stephen J Benkovic Proceedings of the National Academy of Sciences of the United States of America 2001 topics set
Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III. David Jeruzalmi, Olga Yurieva, Yaofeng Zhao, M Young, Jelena Stewart, M Hingorani, Mike E O'Donnell, John Kuriyan Cell 2001 topics set
Identification of hydrogen bonds between Escherichia coli DNA polymerase I (Klenow fragment) and the minor groove of DNA by amino acid substitution of the polymerase and atomic substitution of the DNA. Thomas E Spratt Biochemistry 2001 pols set
Dynamics of translesion DNA synthesis catalyzed by the bacteriophage T4 exonuclease-deficient DNA polymerase. Anthony J Berdis Biochemistry 2001 pols set
Oxygen free radical damage to DNA. Translesion synthesis by human DNA polymerase eta and resistance to exonuclease action at cyclopurine deoxynucleoside residues. Isao Kuraoka, P Robins, Chikahide Masutani, Fumio Hanaoka, Didier Gasparutto, Jean Cadet, Richard D Wood, T Lindahl The Journal of biological chemistry 2001 pols set
Site-directed mutagenesis of human immunodeficiency virus type 1 reverse transcriptase at amino acid position 138. H Pelemans, A Aertsen, Kristel Van Laethem, A-M Vandamme, Erik De Clercq, María-Jesús Pérez-Pérez, Ana San-Félix, Sonsoles Velázquez, María-José Camarasa, Jan Balzarini Virology 2001 pols set
Identification of a putative binding site for [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine (TSAO) derivatives at the p51-p66 interface of HIV-1 reverse transcriptase. Fátima Rodríguez-Barrios, C Pérez, Esther Lobatón, Sonsoles Velázquez, Cristina Chamorro, Ana San-Félix, María-Jesús Pérez-Pérez, María-José Camarasa, H Pelemans, Jan Balzarini, Federico Gago Journal of medicinal chemistry 2001 pols set
Contacts between the 5' nuclease of DNA polymerase I and its DNA substrate. Y Xu, Olga Potapova, A E Leschziner, Nigel D F Grindley, Catherine M Joyce The Journal of biological chemistry 2001 pols set
Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication. Hong Ling, François Boudsocq, Roger Woodgate, Wei Wen Yang Cell 2001 complete
Impaired repair activity of a truncated DNA polymerase beta protein. Nandan Bhattacharyya, T Banerjee, U Patel, Sanjeev Banerjee Life Sci 2001 new
Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein. J Y Wang, Hong Ling, Wei Wen Yang, R Craigie The EMBO journal 2001 new
Stationary-phase mutation in the bacterial chromosome: recombination protein and DNA polymerase IV dependence. H J Bull, M J Lombardo, Susan M Rosenberg Proceedings of the National Academy of Sciences of the United States of America 2001 new
Replication slippage involves DNA polymerase pausing and dissociation. Enrique Viguera, D Canceill, S Dusko Ehrlich The EMBO journal 2001 new
Amino acids 257 to 288 of mouse p48 control the cooperation of polyomavirus large T antigen, replication protein A, and DNA polymerase alpha-primase to synthesize DNA in vitro. A R Kautz, Klaus Weisshart, A Schneider, Frank Grosse, Heinz Peter Nasheuer J Virol 2001 pols set
A role for DNA polymerase alpha in epigenetic control of transcriptional silencing in fission yeast. Nakayama Ji, R C Allshire, A J Klar, S I Grewal The EMBO journal 2001 new
Duplication of a truncated paralog of the family B DNA polymerase gene Aa-polB in the Agrocybe aegerita mitochondrial genome. G Barroso, F Bois, J Labarère Appl Environ Microbiol 2001 new
DNA polymerase mu, a candidate hypermutase? José F Ruiz, Orlando Domínguez, Teresa Laín de Lera, M Garcia-Díaz, Antonio Bernad, Luis Blanco Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2001 new
The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability. Yong Hwan Jin, R Obert, Peter M J Burgers, Thomas A Kunkel, Michael A Resnick, Dmitry A Gordenin Proceedings of the National Academy of Sciences of the United States of America 2001 partial results
A coordinated interplay: proteins with multiple functions in DNA replication, DNA repair, cell cycle/checkpoint control, and transcription. M Stucki, Igor Stagljar, Z O Jónsson, Ulrich Hübscher Progress in nucleic acid research and molecular biology 2001 new
Replication of the lagging strand: a concert of at least 23 polypeptides. Ulrich Hübscher, Y S Seo Molecules and cells 2001 new
Error-prone DNA polymerases: novel structures and the benefits of infidelity. Errol C Friedberg, Paula L Fischhaber, C Kisker Cell 2001 topics set
Human DNA polymerase beta initiates DNA synthesis during long-patch repair of reduced AP sites in DNA. A J Podlutsky, Irina I Dianova, Vladimir N Podust, Vilhelm A Bohr, Grigory L Dianov The EMBO journal 2001 pols set
Altered nucleotide misinsertion fidelity associated with poliota-dependent replication at the end of a DNA template. Ekaterina G Frank, Agnès Tissier, John P McDonald, V Rapić-Otrin, Xianmin Zeng, Patricia J Gearhart, Roger Woodgate The EMBO journal 2001 pols set
Okazaki fragment processing: modulation of the strand displacement activity of DNA polymerase delta by the concerted action of replication protein A, proliferating cell nuclear antigen, and flap endonuclease-1. Giovanni Maga, Giuseppe Villani, V Tillement, M Stucki, Giada A Locatelli, Isabelle Frouin, Silvio Spadari, Ulrich Hübscher Proceedings of the National Academy of Sciences of the United States of America 2001 new
Structure of DNA polymerase delta from Saccharomyces cerevisiae. Erik Johansson, Jerzy Majka, Peter M J Burgers The Journal of biological chemistry 2001 topics set
Base sequence dependence of in vitro translesional DNA replication past a bulky lesion catalyzed by the exo- Klenow fragment of Pol I. P Zhuang, Alexander Kolbanovskiy, Shantu Amin, Nicholas E Geacintov Biochemistry 2001 pols set
Recognition of template-primer and gapped DNA substrates by the human DNA polymerase beta. Surendran Rajendran, Maria J Jezewska, Wlodzimierz Bujalowski Journal of molecular biology 2001 pols set
Oxidation of thymine to 5-formyluracil in DNA promotes misincorporation of dGMP and subsequent elongation of a mismatched primer terminus by DNA polymerase. Aya Masaoka, Hiroaki Terato, M Kobayashi, Y Ohyama, Hiroshi Ide The Journal of biological chemistry 2001 pols set
Crystal structures of a ddATP-, ddTTP-, ddCTP, and ddGTP- trapped ternary complex of Klentaq1: insights into nucleotide incorporation and selectivity. Yingqian Li, Gabriel Waksman Protein science : a publication of the Protein Society 2001 topics set
The telomerase reverse transcriptase promoter drives efficacious tumor suicide gene therapy while preventing hepatotoxicity encountered with constitutive promoters. Anish S Majumdar, D E Hughes, S P Lichtsteiner, Zhengqiang Wang, Jane S Lebkowski, A P Vasserot Gene therapy 2001 new
Human DNA polymerase iota: wrong for the right reasons. M Sander Environ Health Perspect 2001 pols set
Methylglyoxal, an endogenous aldehyde, crosslinks DNA polymerase and the substrate DNA. N Murata-Kamiya, Hiroyuki Kamiya Nucleic acids research 2001 new
Potentiation of inhibition of wild-type and mutant human immunodeficiency virus type 1 reverse transcriptases by combinations of nonnucleoside inhibitors and d- and L-(beta)-dideoxynucleoside triphosphate analogs. Giovanni Maga, Ulrich Hübscher, M Pregnolato, D Ubiali, G Gosselin, Silvio Spadari Antimicrobial agents and chemotherapy 2001 new
A single highly mutable catalytic site amino acid is critical for DNA polymerase fidelity. P H Patel, H Kawate, E Adman, M Ashbach, Lawrence A Loeb The Journal of biological chemistry 2001 new
Inhibition of purified recombinant reverse transcriptase from wild-type and zidovudine-resistant clinical isolates of human immunodeficiency virus type 1 by zidovudine, stavudine, and lamivudine triphosphates. C Duan, D Poticha, T C Stoeckli, Christos J Petropoulos, Jeannette M Whitcomb, Charles S McHenry, D R Kuritzkes The Journal of infectious diseases 2001 new
Response of human DNA polymerase iota to DNA lesions. Yongqing Zhang, Fenghua Yuan, Xiaoming Wu, John-Stephen Taylor, Zhengqiang Wang Nucleic acids research 2001 pols set
The translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation. H Zan, A Komori, Zhongjie Li, A Cerutti, A Schaffer, M F Flajnik, Marilyn Diaz, P Casali Immunity 2001 topics set
Evolution and the molecular basis of somatic hypermutation of antigen receptor genes. Marilyn Diaz, M F Flajnik, N Klinman Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2001 topics set
Insight into the catalytic mechanism of DNA polymerase beta: structures of intermediate complexes. J W Arndt, W Gong, Xuejun Zhong, Alexander K Showalter, Jianhua Liu, Christopher A Dunlap, Z Lin, C Paxson, Ming-Daw Tsai, M K Chan Biochemistry 2001 topics set
Translesional synthesis past acetylaminofluorene-derived DNA adducts catalyzed by human DNA polymerase kappa and Escherichia coli DNA polymerase IV. Naomi Suzuki, Eiji Ohashi, Kiyoshi Hayashi, Haruo Ohmori, Arthur P Grollman, Shinya Shibutani Biochemistry 2001 pols set
Probing DNA polymerase fidelity mechanisms using time-resolved fluorescence anisotropy. Michael F Bailey, Elizabeth H Z Thompson, David P Millar Methods 2001 pols set
Interference of gemcitabine triphosphate with the measurements of deoxynucleotides using an optimized DNA polymerase elongation assay. K Smid, C J Van Moorsel, P Noordhuis, D A Voorn, G J Peters Int J Oncol 2001 new
Exploitation of the low fidelity of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase and the nucleotide composition bias in the HIV-1 genome to alter the drug resistance development of HIV. Jan Balzarini, María-José Camarasa, María-Jesús Pérez-Pérez, Ana San-Félix, Sonsoles Velázquez, CF Perno, Erik De Clercq, J N Anderson, Anna Karlsson Journal of virology 2001 pols set
Yeast DNA polymerase eta utilizes an induced-fit mechanism of nucleotide incorporation. M Todd Washington, Louise Prakash, Satya Prakash Cell 2001 partial results
Crystal structure of a DinB lesion bypass DNA polymerase catalytic fragment reveals a classic polymerase catalytic domain. B L Zhou, Janice D Pata, Thomas A Steitz Molecular cell 2001 topics set
Monoclonal antibodies against human telomerase reverse transcriptase (hTERT): preparation, characterization, and application. Shaomin Yang, Bin Zhang, Jiaochen Wang, Songlin Liao, Jisheng Han, Jianping Wei, Lin Hou Hybridoma 2001 new
Building a replisome solution structure by elucidation of protein-protein interactions in the bacteriophage T4 DNA polymerase holoenzyme. S C Alley, Michael A Trakselis, M U Mayer, Faoud T Ishmael, A D Jones, Stephen J Benkovic The Journal of biological chemistry 2001 topics set
Archaeal primase: bridging the gap between RNA and DNA polymerases. A A Bocquier, L Liu, Isaac K O Cann, Kayoko Komori, Daisuke Kohda, Yoshizumi Ishino Current biology : CB 2001 new
The archaeal DNA primase: biochemical characterization of the p41-p46 complex from Pyrococcus furiosus. L Liu, Kayoko Komori, Sonoko Ishino, A A Bocquier, Isaac K O Cann, Daisuke Kohda, Yoshizumi Ishino The Journal of biological chemistry 2001 new
Replication-related activities establish cohesion between sister chromatids. Zhengqiang Wang, Michael F Christman Cell biochemistry and biophysics 2001 new
Three-dimensional electron microscopy of the clamp loader small subunit from Pyrococcus furiosus. Kouta Mayanagi, Tomoko Miyata, Takuji Oyama, Yoshizumi Ishino, Kosuke Morikawa Journal of structural biology 2001 new
3'-5' Exonucleolytic activity of DNA polymerases: structural features that allow kinetic discrimination between ribo- and deoxyribonucleotide residues. T C Lin, C X Wang, Catherine M Joyce, William H Konigsberg Biochemistry 2001 complete
Invariant Asp-1122 and Asp-1124 are essential residues for polymerization catalysis of family D DNA polymerase from Pyrococcus horikoshii. Yulong Shen, K Musti, M Hiramoto, H Kikuchi, Y Kawarabayashi, Ikuo Matsui The Journal of biological chemistry 2001 pols set
Enzymatic properties of rat DNA polymerase beta mutants obtained by randomized mutagenesis. A Skandalis, Lawrence A Loeb Nucleic acids research 2001 new
Y265H mutator mutant of DNA polymerase beta. Proper teometric alignment is critical for fidelity. Amit M Shah, Shu-Xia Li, Karen S Anderson, Joann B Sweasy The Journal of biological chemistry 2001 new
HIV-1 integration as a target for antiretroviral therapy: a review. Wim Pluymers, Erik De Clercq, Zeger Debyser Current drug targets. Infectious disorders 2001 pols set
Roles of yeast DNA polymerases delta and zeta and of Rev1 in the bypass of abasic sites. Lajos Haracska, Ildiko Unk, Robert E Johnson, Erik Johansson, Peter M J Burgers, Satya Prakash, Louise Prakash Genes Dev 2001 new
Inefficient bypass of an abasic site by DNA polymerase eta. Lajos Haracska, M Todd Washington, Satya Prakash, Louise Prakash The Journal of biological chemistry 2001 new
Inhibition of HIV infection by CXCR4 and CCR5 chemokine receptor antagonists. Erik De Clercq, Dominique Schols Antiviral chemistry & chemotherapy 2001 pols set
A novel PCNA-binding motif identified by the panning of a random peptide display library. H Xu, Peiming Zhang, Lingfeng Liu, Marietta Y W T Lee Biochemistry 2001 new
Evaluating phenotype and genotype of drug-resistant strains in herpesviruses. Graciella Andrei, Pierre Fiten, Erik De Clercq, Robert Snoeck, Ghislain Opdenakker Molecular biotechnology 2001 pols set
Energetics and specificity of Rat DNA polymerase beta interactions with template-primer and gapped DNA substrates. Maria J Jezewska, Surendran Rajendran, Wlodzimierz Bujalowski The Journal of biological chemistry 2001 new
The anti-herpesvirus activity of (1'S,2'R)-9-[[1',2'-bis(hydroxymethyl)-cycloprop-1'-yl]methyl]guanine is markedly potentiated by the immunosuppressive agent mycophenolate mofetil. Johan Neyts, Erik De Clercq Antiviral research 2001 new
Evolution of the two-step model for UV-mutagenesis. Roger Woodgate Mutation research 2001 new
Unique misinsertion specificity of poliota may decrease the mutagenic potential of deaminated cytosines. Alexandra Vaisman, Roger Woodgate The EMBO journal 2001 new
Structure of the catalytic core of S. cerevisiae DNA polymerase eta: implications for translesion DNA synthesis. José Trincao, Robert E Johnson, Carlos R Escalante, Satya Prakash, Louise Prakash, Aneel K Aggarwal Molecular cell 2001 new
A model for SOS-lesion-targeted mutations in Escherichia coli. Phuong Pham, Jeffrey G Bertram, Mike E O'Donnell, Roger Woodgate, Myron F Goodman Nature 2001 new
Roles of DNA polymerases V and II in SOS-induced error-prone and error-free repair in Escherichia coli. Phuong Pham, Sneha Rangarajan, Roger Woodgate, Myron F Goodman Proceedings of the National Academy of Sciences of the United States of America 2001 new
Functional characterization of chimeric reverse transcriptases with polypeptide subunits of highly divergent HIV-1 group M and O strains. L Menéndez-Arias, A Abraha, ME Quiñones-Mateu, Antonio Mas, M J Camarasa, E J Arts The Journal of biological chemistry 2001 pols set
tau binds and organizes Escherichia coli replication through distinct domains. Partial proteolysis of terminally tagged tau to determine candidate domains and to assign domain V as the alpha binding domain. D Gao, Charles S McHenry The Journal of biological chemistry 2001 pols set
tau binds and organizes Escherichia coli replication proteins through distinct domains. Domain IV, located within the unique C terminus of tau, binds the replication fork, helicase, DnaB. D Gao, Charles S McHenry The Journal of biological chemistry 2001 new
tau binds and organizes Escherichia coli replication proteins through distinct domains: domain III, shared by gamma and tau, oligomerizes DnaX. Bradley P Glover, Arthur E Pritchard, Charles S McHenry The Journal of biological chemistry 2001 new
Unwinding the molecular basis of the Werner syndrome. J Shen, Lawrence A Loeb Mechanisms of ageing and development 2001 new
In vitro replication slippage by DNA polymerases from thermophilic organisms. Enrique Viguera, D Canceill, S Dusko Ehrlich Journal of molecular biology 2001 partial results
Clamp loader structure predicts the architecture of DNA polymerase III holoenzyme and RFC. Mike E O'Donnell, David Jeruzalmi, John Kuriyan Current biology : CB 2001 pols set
Carboxyl-terminal domain III of the delta' subunit of DNA polymerase III holoenzyme binds DnaX and supports cooperative DnaX complex assembly. Min-Sun Song, Charles S McHenry The Journal of biological chemistry 2001 new
DNA polymerase epsilon is required for coordinated and efficient chromosomal DNA replication in Xenopus egg extracts. Shou Waga, T Masuda, H Takisawa, Akio Sugino Proceedings of the National Academy of Sciences of the United States of America 2001 new
Essential lysine residues in the RNA polymerase domain of the gene 4 primase-helicase of bacteriophage T7. Seung-Joo Lee, Charles C Richardson The Journal of biological chemistry 2001 new
Interactions of the 8-kDa domain of rat DNA polymerase beta with DNA. Maria J Jezewska, Surendran Rajendran, Wlodzimierz Bujalowski Biochemistry 2001 new
Mutagenesis in eukaryotes dependent on DNA polymerase zeta and Rev1p. Christopher W Lawrence, Veronica M Maher Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2001 topics set
Eukaryotic mutagenesis and translesion replication dependent on DNA polymerase zeta and Rev1 protein. Christopher W Lawrence, Veronica M Maher Biochem Soc Trans 2001 topics set
Structures of complexes formed by HIV-1 reverse transcriptase at a termination site of DNA synthesis. M Lavigne, L Polomack, H Buc The Journal of biological chemistry 2001 pols set
Structure of the gene 2.5 protein, a single-stranded DNA binding protein encoded by bacteriophage T7. Thomas Hollis, J M Stattel, D S Walther, Charles C Richardson, Tom Ellenberger Proceedings of the National Academy of Sciences of the United States of America 2001 pols set
Replication protein A as a "fidelity clamp" for DNA polymerase alpha. Giovanni Maga, Isabelle Frouin, Silvio Spadari, Ulrich Hubscher The Journal of biological chemistry 2001 new
A mutation in the primer grip region of HIV-1 reverse transcriptase that confers reduced fidelity of DNA synthesis. M Gutiérrez-Rivas, L Menéndez-Arias Nucleic acids research 2001 pols set
E2F regulates growth-dependent transcription of genes encoding both catalytic and regulatory subunits of mouse primase. N Nishikawa, M Izumi, Masayuki Yokoi, Hiroshi Miyazawa, Fumio Hanaoka Genes to cells : devoted to molecular & cellular mechanisms 2001 new
Mutagenic and nonmutagenic bypass of DNA lesions by Drosophila DNA polymerases dpoleta and dpoliota. T Ishikawa, N Uematsu, T Mizukoshi, Shigenori Iwai, Hiroshi Iwasaki, Chikahide Masutani, Fumio Hanaoka, R Ueda, Haruo Ohmori, T Todo The Journal of biological chemistry 2001 new
DNA synthesis and dRPase activities of polymerase beta are both essential for single-nucleotide patch base excision repair in mammalian cell extracts. A J Podlutsky, Irina I Dianova, Samuel H Wilson, Vilhelm A Bohr, Grigory L Dianov Biochemistry 2001 new
A role for p53 in base excision repair. J Zhou, J Ahn, Samuel H Wilson, C Prives The EMBO journal 2001 new
Photoaffinity labeling of mouse fibroblast enzymes by a base excision repair intermediate. Evidence for the role of poly(ADP-ribose) polymerase-1 in DNA repair. Olga I Lavrik, Rajendra Prasad, Robert W Sobol, Julie K Horton, E J Ackerman, Samuel H Wilson The Journal of biological chemistry 2001 new
DNA damage-induced mutagenesis : a novel target for cancer prevention. Zhengqiang Wang Molecular interventions 2001 new
RNA virus error catastrophe: direct molecular test by using ribavirin. S Crotty, C E Cameron, R Andino Proceedings of the National Academy of Sciences of the United States of America 2001 new
Molecular modeling and biochemical characterization reveal the mechanism of hepatitis B virus polymerase resistance to lamivudine (3TC) and emtricitabine (FTC). Kalyan Das, X Xiong, Huiling Yang, Christopher E Westland, Craig S Gibbs, Stefan G Sarafianos, Edward Arnold J Virol 2001 new
4'-C-substituted-2'-deoxynucleosides: a family of antiretroviral agents which are potent against drug-resistant HIV variants. Hiroshi Ohrui, Hiroyuki Mitsuya Curr Drug Targets Infect Disord 2001 topics set
An introduction to nucleoside and nucleotide analogues. K E Squires Antivir Ther 2001 topics set
YADD mutants of human immunodeficiency virus type 1 and Moloney murine leukemia virus reverse transcriptase are resistant to lamivudine triphosphate (3TCTP) in vitro. Paul L Boyer, Hong Qiang Gao, Patrick K Clark, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes J Virol 2001 topics set
Role of DNA polymerase zeta in the bypass of a (6-4) TT photoproduct. Robert E Johnson, Lajos Haracska, Satya Prakash, Louise Prakash Molecular and cellular biology 2001 new
Relationship between base excision repair capacity and DNA alkylating agent sensitivity in mouse monocytes. K H Chen, Deepak K Srivastava, Samuel H Wilson Mutation research 2001 new
Investigation of the dNTP-binding site of HIV-1 reverse transcriptase using photoreactive analogs of dNTP. A L Zakharenko, Dmitry M Kolpashchikov, Svetlana N Khodyreva, Olga I Lavrik, L Menéndez-Arias Biochemistry. Biokhimii͡a 2001 pols set
A novel interaction of tRNA(Lys,3) with the feline immunodeficiency virus RNA genome governs initiation of minus strand DNA synthesis. Jennifer T Miller, Bernard Ehresmann, Ulrich Hübscher, Stuart F J Le Grice The Journal of biological chemistry 2001 pols set
Crystal structure and deletion analysis show that the accessory subunit of mammalian DNA polymerase gamma, Pol gamma B, functions as a homodimer. José A Carrodeguas, K Theis, Daniel F Bogenhagen, Caroline Kisker Molecular cell 2001 pols set
The large fragment of Escherichia coli DNA polymerase I can synthesize DNA exclusively from fluorescently labeled nucleotides. S Brakmann, P Nieckchen Chembiochem 2001 pols set
Biochemical analysis of point mutations in the 5'-3' exonuclease of DNA polymerase I of Streptococcus pneumoniae. Functional and structural implications. M Amblar, M G de Lacoba, M A Corrales, P Lopez The Journal of biological chemistry 2001 pols set
[Hepatitis B virus DNA polymerase]. T Łoch, A Pawińska-Zdziebłowska, M H Fic Przegl Epidemiol 2001 new
Enhanced expression and activity of DNA polymerase beta in human ovarian tumor cells: impact on sensitivity towards antitumor agents. Valérie Bergoglio, Yvan Canitrot, L Hogarth, L Minto, S B Howell, Christophe Cazaux, Jean-Sébastien Hoffmann Oncogene 2001 new
Error rate and specificity of human and murine DNA polymerase eta. Toshiro Matsuda, Katarzyna Bebenek, Chikahide Masutani, Igor B Rogozin, Fumio Hanaoka, Thomas A Kunkel Journal of molecular biology 2001 partial results
Interaction of DNA polymerase beta with GRIP1 during meiosis. Alan S Jonason, S M Baker, Joann B Sweasy Chromosoma 2001 new
Enhanced ribonucleotide incorporation by an O-helix mutant of Thermus aquaticus DNA polymerase I. Masanori Ogawa, A Tosaka, Yasutomo Ito, Shonen Yoshida, Motoshi Suzuki Mutation research 2001 pols set
Specific interaction between an oligosaccharide on the tumor cell surface and the novel antitumor agents, sulfoquinovosylacylglycerols. Keisuke Ohta, Yoshiyuki Mizushina, Takayuki Yamazaki, Shinya Hanashima, Fumio Sugawara, Kengo Sakaguchi Biochemical and biophysical research communications 2001 new
Synthetic activity of Sso DNA polymerase Y1, an archaeal DinB-like DNA polymerase, is stimulated by processivity factors proliferating cell nuclear antigen and replication factor C. Petr Grúz, Francesca M Pisani, Masatomi Shimizu, Masami Yamada, I Hayashi, Kosuke Morikawa, Takehiko Nohmi The Journal of biological chemistry 2001 pols set
Inferred hepatitis C virus quasispecies diversity is influenced by choice of DNA polymerase in reverse transcriptase-polymerase chain reactions. B Mullan, E Kenny-Walsh, J K Collins, F Shanahan, L J Fanning Anal Biochem 2001 new
Quinoxalinylethylpyridylthioureas (QXPTs) as potent non-nucleoside HIV-1 reverse transcriptase (RT) inhibitors. Further SAR studies and identification of a novel orally bioavailable hydrazine-based antiviral agent. Giuseppe Campiani, F Aiello, M Fabbrini, Elena Morelli, Anna Ramunno, S Armaroli, Vito Nacci, A Garofalo, Giovanni Greco, Ettore Novellino, Giovanni Maga, Silvio Spadari, Alberto Bergamini, L Ventura, B Bongiovanni, M Capozzi, F Bolacchi, Stefano Marini, Massimo Coletta, G Guiso, S Caccia Journal of medicinal chemistry 2001 pols set
Genetic interactions between the Escherichia coli umuDC gene products and the beta processivity clamp of the replicative DNA polymerase. Mark D Sutton, M F Farrow, B M Burton, Graham C Walker J Bacteriol 2001 new
A DNA polymerase with specificity for five base pairs. Alexander K Showalter, Ming-Daw Tsai Journal of the American Chemical Society 2001 new
The Drosophila Dpit47 protein is a nuclear Hsp90 co-chaperone that interacts with DNA polymerase alpha. G Crevel, H Bates, H Huikeshoven, S Cotterill J Cell Sci 2001 new
Design and synthesis of novel antibacterial agents with inhibitory activity against DNA polymerase III. Amjad Ali, S D Aster, D W Graham, G F Patel, Gayle E Taylor, R L Tolman, R E Painter, Lynn L Silver, Katherine Young, Ken Ellsworth, W Geissler, G S Harris Bioorganic & medicinal chemistry letters 2001 new
Identification of DNA polymerase delta in eggs of a teleost fish (loach). N P Sharova, D D Dimitrova, E B Abramova, S B Dmitrieva, V S Mikhailov Biochemistry (Mosc) 2001 new
Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain. V Molteni, J Greenwald, D Rhodes, Y Hwang, W Kwiatkowski, F D Bushman, J S Siegel, S Choe Acta Crystallogr D Biol Crystallogr 2001 new
Evolution of anti-HIV drug candidates. Part 3: Diarylpyrimidine (DAPY) analogues. Donald W Ludovici, B L De Corte, Michael J Kukla, Hong Ye, Chih Y Ho, Mark A Lichtenstein, Robert W Kavash, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, Paul J Lewi, Jan Heeres, Lucien M H Koymans, Marc R De Jonge, Koen J A Van Aken, Frits F D Daeyaert, Kalyan Das, Edward Arnold, Paul A J Janssen Bioorganic & medicinal chemistry letters 2001 new
Rapid amplification of plasmid and phage DNA using Phi 29 DNA polymerase and multiply-primed rolling circle amplification. F B Dean, John R Nelson, Theresa L Giesler, R S Lasken Genome Res 2001 pols set
Mediation of proliferating cell nuclear antigen (PCNA)-dependent DNA replication through a conserved p21(Cip1)-like PCNA-binding motif present in the third subunit of human DNA polymerase delta. M Ducoux, Serge Urbach, Giuseppe Baldacci, Ulrich Hübscher, Stéphane Koundrioukoff, J Christensen, Patrick Hughes The Journal of biological chemistry 2001 pols set
Effects of glutathione on chromium-induced DNA crosslinking and DNA polymerase arrest. T O'Brien, J Xu, Steven R Patierno Mol Cell Biochem 2001 pols set
Clustered charge-to-alanine mutagenesis of the vaccinia virus A20 gene: temperature-sensitive mutants have a DNA-minus phenotype and are defective in the production of processive DNA polymerase activity. A Punjabi, K Boyle, J DeMasi, O Grubisha, B Unger, M Khanna, P Traktman J Virol 2001 pols set
The fidelity of human DNA polymerase gamma with and without exonucleolytic proofreading and the p55 accessory subunit. Matthew J Longley, Dinh Nguyen, Thomas A Kunkel, William C Copeland The Journal of biological chemistry 2001 partial results
Targeting of human DNA polymerase iota to the replication machinery via interaction with PCNA. Lajos Haracska, Robert E Johnson, Ildiko Unk, Barbara B Phillips, Jerard Hurwitz, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2001 pols set
Molecular matchmaking: NNRTIs can enhance the dimerization of HIV type 1 reverse transcriptase. Stephen H Hughes Proceedings of the National Academy of Sciences of the United States of America 2001 pols set
O-helix mutant T664P of Thermus aquaticus DNA polymerase I: altered catalytic properties for incorporation of incorrect nucleotides but not correct nucleotides. A Tosaka, Masanori Ogawa, Shonen Yoshida, Motoshi Suzuki The Journal of biological chemistry 2001 pols set
DNA polymerase iota and related rad30-like enzymes. John P McDonald, Agnès Tissier, Ekaterina G Frank, Shigenori Iwai, Fumio Hanaoka, Roger Woodgate Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2001 new
Interacting fidelity defects in the replicative DNA polymerase of bacteriophage RB69. Anna Bebenek, Holly Kloos Dressman, Geraldine T Carver, S Ng , Vasiliy M Petrov, Guangwei Yang, William H Konigsberg, Jim D Karam, John W Drake The Journal of biological chemistry 2001 complete
Loss of mitochondrial DNA in rabbit bladder smooth muscle following partial outlet obstruction results from lack of organellar DNA replication. Zhengqiang Wang, Xiaoming Wu, R M Levin, A P Hudson Molecular urology 2001 new
Translesion synthesis by the UmuC family of DNA polymerases. Zhengqiang Wang Mutation research 2001 new
Purification and characterization of pol kappa, a DNA polymerase encoded by the human DINB1 gene. Valerie L Gerlach, William J Feaver, Paula L Fischhaber, Errol C Friedberg The Journal of biological chemistry 2001 partial results
HIV-1 reverse transcriptase and integrase enzymes physically interact and inhibit each other. Taurai Tasara, Giovanni Maga, Michael O Hottiger, Ulrich Hübscher FEBS letters 2001 pols set
Anatomy of the primase-alpha DNA polymerase reaction accomplished by nucleoprotein complexes harboring an extrachromosomal DNA identical with avian myeloblastosis virus core-bound DNA: influencing by carbonyldiphosphonate, mimosine and butylphenyl deoxyguanosine-5'-triphosphate. J Ríman Acta Virol 2001 new
Mechanisms of HIV-1 nucleoside reverse transcriptase inhibitor resistance: is it all figured out? Lisa K Naeger, Michael D Miller Curr Opin Investig Drugs 2001 topics set
DNA polymerase kappa, implicated in spontaneous and DNA damage-induced mutagenesis, is overexpressed in lung cancer. Jiyang O-Wang, Kiyoko Kawamura, Y Tada, Haruo Ohmori, Hiroshi Kimura, Shigeru Sakiyama, Masatoshi Tagawa Cancer research 2001 new
Fidelity of nucleotide incorporation by human mitochondrial DNA polymerase. Allison A Johnson, Kenneth A Johnson The Journal of biological chemistry 2001 topics set
A Mutation in the gene-encoding bacteriophage T7 DNA polymerase that renders the phage temperature-sensitive. Jaya K Kumar, R Kremsdorf, Stanley Tabor, Charles C Richardson The Journal of biological chemistry 2001 pols set
Roles of chromosomal and episomal dinB genes encoding DNA pol IV in targeted and untargeted mutagenesis in Escherichia coli. Su-Ryang Kim, Keiko Matsui, Masami Yamada, Petr Gruz, Takehiko Nohmi Molecular genetics and genomics : MGG 2001 pols set
Correlation between viral resistance to zidovudine and resistance at the reverse transcriptase level for a panel of human immunodeficiency virus type 1 mutants. Johan Lennerstrand, Kurt Hertogs, David K Stammers, Brendan A Larder J Virol 2001 topics set
Bacteriophage T4 proteins replicate plasmids with a preformed R loop at the T4 ori(uvsY) replication origin in vitro. Nancy G Nossal, K C Dudas, K N Kreuzer Molecular cell 2001 complete
Miscoding potential of the N2-ethyl-2'-deoxyguanosine DNA adduct by the exonuclease-free Klenow fragment of Escherichia coli DNA polymerase I. I Terashima, Toshiro Matsuda, T W Fang, Naomi Suzuki, J Kobayashi, K Kohda, Shinya Shibutani Biochemistry 2001 partial results
Conditional coupling of leading-strand and lagging-strand DNA synthesis at bacteriophage T4 replication forks. Farid A Kadyrov, John W Drake The Journal of biological chemistry 2001 complete
Nonnucleoside reverse transcriptase inhibitors are chemical enhancers of dimerization of the HIV type 1 reverse transcriptase. G Tachedjian, M Orlova, Stefan G Sarafianos, Edward Arnold, S P Goff Proceedings of the National Academy of Sciences of the United States of America 2001 new
DNA polymerases from hyperthermophiles. Holly H Hogrefe, J Cline, A E Lovejoy, K B Nielson Methods in enzymology 2001 partial results
A mutation in subunit B of the DNA polymerase alpha-primase complex from Novikoff hepatoma cells concomitant with a conformational change and abnormal catalytic properties of the DNA polymerase alpha-primase complex. O Popanda, C Flohr, J C Dai, A Hunzicker, H W Thielmann Mol Carcinog 2001 new
Role for human immunodeficiency virus type 1 Tat protein in suppression of viral reverse transcriptase activity during late stages of viral replication. Masanori Kameoka, Liwei Rong, Matthias Götte, Chen Liang, Rodney S Russell, Mark A. Wainberg Journal of virology 2001 pols set
Structure of the replicating complex of a pol alpha family DNA polymerase. M C Franklin, Jianhong Wang, Thomas A Steitz Cell 2001 topics set
The human homologue of fission Yeast cdc27, p66, is a component of active human DNA polymerase delta. K Shikata, S Ohta, Kohei Yamada, C Obuse, Hirofumi Yoshikawa, Toshiki Tsurimoto J Biochem 2001 pols set
Getting a grip on how DNA polymerases function. P H Patel, Lawrence A Loeb Nat Struct Biol 2001 new
Synthesis of sulfoquinovosylacylglycerols, inhibitors of eukaryotic DNA polymerase alpha and beta. Shinya Hanashima, Yoshiyuki Mizushina, Takayuki Yamazaki, Keisuke Ohta, Shunya Takahashi, Hiroeki Sahara, Kengo Sakaguchi, F Sugawar Bioorg Med Chem 2001 new
Dynamic protein interactions in the bacteriophage T4 replisome. Michael A Trakselis, M U Mayer, Faoud T Ishmael, Rosa Maria Roccasecca, Stephen J Benkovic Trends in biochemical sciences 2001 topics set
In vivo consequences of putative active site mutations in yeast DNA polymerases alpha, epsilon, delta, and zeta. Youri I Pavlov, Polina V Shcherbakova, Thomas A Kunkel Genetics 2001 new
DNA damage control by novel DNA polymerases: translesion replication and mutagenesis. Zvi Livneh The Journal of biological chemistry 2001 new
Functional interactions of an archaeal sliding clamp with mammalian clamp loader and DNA polymerase delta. Yoshizumi Ishino, Toshiki Tsurimoto, Sonoko Ishino, Isaac K O Cann Genes Cells 2001 new
Prokaryotic DNA polymerase I: evolution, structure, and "base flipping" mechanism for nucleotide selection. P H Patel, Motoshi Suzuki, E Adman, A Shinkai, Lawrence A Loeb Journal of molecular biology 2001 new
Structure of a pseudo-16-mer DNA with stacked guanines and two G-A mispairs complexed with the N-terminal fragment of Moloney murine leukemia virus reverse transcriptase. Marie L Coté, Millie M Georgiadis Acta Crystallogr D Biol Crystallogr 2001 topics set
Three-dimensional structural model analysis of the binding site of lithocholic acid, an inhibitor of DNA polymerase beta and DNA topoisomerase II. Yoshiyuki Mizushina, Nobuyuki Kasai, Fumio Sugawara, A Iida, Hiromi Yoshida, Kengo Sakaguchi J Biochem 2001 pols set
DNA primases. David N Frick, Charles C Richardson Annual review of biochemistry 2001 new
Highly frequent frameshift DNA synthesis by human DNA polymerase mu. Yongqing Zhang, Xiaoming Wu, Fenghua Yuan, Zhongwen Xie, Zhengqiang Wang Molecular and cellular biology 2001 partial results
Schizosaccharomyces pombe cells lacking the amino-terminal catalytic domains of DNA polymerase epsilon are viable but require the DNA damage checkpoint control. W Feng, G D'Urso Molecular and cellular biology 2001 new
Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): an archaeal DinB-like DNA polymerase with lesion-bypass properties akin to eukaryotic poleta. François Boudsocq, Shigenori Iwai, Fumio Hanaoka, Roger Woodgate Nucleic acids research 2001 partial results
Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)n trinucleotide repeat sequence. Ashwini S Kamath-Loeb, Lawrence A Loeb, Erik Johansson, Peter M J Burgers, M Fry The Journal of biological chemistry 2001 new
Stimulation of DNA polymerase alpha by hypergravity generated by centrifugal acceleration. Masaharu Takemura, Shonen Yoshida Biochem Biophys Res Commun 2001 new
Origin of an animal mitochondrial DNA polymerase subunit via lineage-specific acquisition of a glycyl-tRNA synthetase from bacteria of the Thermus-Deinococcus group. Y I Wolf, Eugene V Koonin Trends Genet 2001 new
A DNA polymerase epsilon inhibitor activates the ribo and deoxyribo modes of primase expression and induces a unique phenomenon of primer accumulation. J Ríman FEBS letters 2001 new
DNA polymerase beta imbalance increases apoptosis and mutagenesis induced by oxidative stress. Mathilde Fréchet, Yvan Canitrot, Christophe Cazaux, Jean-Sébastien Hoffmann FEBS letters 2001 new
A binary system of photoreagents for high-efficiency labeling of DNA polymerases. Natalia A Lebedeva, Dmitry M Kolpashchikov, Nadejda I Rechkunova, Svetlana N Khodyreva, Olga I Lavrik Biochemical and biophysical research communications 2001 new
Affinity labeling of flap-endonuclease FEN-1 by photoreactive DNAs. D Y Khlimankov, Nadejda I Rechkunova, Dmitry M Kolpashchikov, Svetlana N Khodyreva, Olga I Lavrik Biochemistry. Biokhimii͡a 2001 new
[Reagents for modification of protein-nucleic complexes. III. Site-specific photomodification of elongation complex of DNA polymerase beta with arylazide derivatives of primers sensitized with fluorescent ATP gamma-amide]. I V Safronov, I A Drachkova, Irina O Petruseva, Svetlana N Khodyreva, M I Dobrikov, T M Ivanova, G V Shishkin, O V Lavrik Bioorg Khim 2001 pols set
Analysis of efficiency and fidelity of HIV-1 (+)-strand DNA synthesis reveals a novel rate-limiting step during retroviral reverse transcription. Matthias Götte, Masanori Kameoka, N McLellan, Luciano Cellai, Mark A. Wainberg The Journal of biological chemistry 2001 pols set
Assembly of DNA polymerase III holoenzyme: co-assembly of gamma and tau is inhibited by DnaX complex accessory proteins but stimulated by DNA polymerase III core. Arthur E Pritchard, Charles S McHenry The Journal of biological chemistry 2001 new
Quantitation of heteroplasmy in mitochondrial DNA mutations by primer extension using Vent(R)(exo-) DNA polymerase and RFLP analysis. F K Jacobi, J Meyer, C M Pusch, B Wissinger Mutation research 2001 new
The ring-type polymerase sliding clamp family. Irina Bruck, Mike E O'Donnell Genome biology 2001 topics set
Estrogenic upregulation of DNA polymerase beta in oocytes of preovulatory ovine follicles. W J Murdoch, E A Van Kirk Mol Reprod Dev 2001 new
Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase. Allison A Johnson, Adrian S Ray, Jeremiah Hanes, Zucai Suo, J M Colacino, Karen S Anderson, Kenneth A Johnson The Journal of biological chemistry 2001 new
The conserved active site motif A of Escherichia coli DNA polymerase I is highly mutable. A Shinkai, P H Patel, Lawrence A Loeb The Journal of biological chemistry 2001 pols set
Acidic residues critical for the activity and biological function of yeast DNA polymerase eta. Christine M Kondratick, M Todd Washington, Satya Prakash, Louise Prakash Molecular and cellular biology 2001 topics set
Crystal structure of a DinB family error-prone DNA polymerase from Sulfolobus solfataricus. L F Silvian, E A Toth, Phuong Pham, Myron F Goodman, Tom Ellenberger Nat Struct Biol 2001 topics set
Mutations at the mitochondrial DNA polymerase (POLG) locus associated with male infertility. Anja T Rovio, D R Marchington, S Donat, H C Schuppe, J Abel, E Fritsche, D J Elliott, P Laippala, A L Ahola, D McNay, R F Harrison, B Hughes, T Barrett, D M Bailey, D Mehmet, A M Jequier, T B Hargreave, S H Kao, J M Cummins, D E Barton, H J Cooke, Y H Wei, L Wichmann, J Poulton, Howard T Jacobs Nat Genet 2001 new
Somatic mutation hotspots correlate with DNA polymerase eta error spectrum. Igor B Rogozin, Youri I Pavlov, Katarzyna Bebenek, Toshiro Matsuda, Thomas A Kunkel Nat Immunol 2001 new
A novel role of XRCC1 in the functions of a DNA polymerase beta variant. Nandan Bhattacharyya, Sanjeev Banerjee Biochemistry 2001 new
Molecular mechanisms of the functional coupling of the helicase (gp41) and polymerase (gp43) of bacteriophage T4 within the DNA replication fork. Emmanuelle Delagoutte, Peter H von Hippel Biochemistry 2001 complete
Antitumor activity of 2',3'-dideoxycytidine nucleotide analog against tumors up-regulating DNA polymerase beta. T Louat, Laurence Servant, M P Rols, Anne Bieth, J Teissie, Jean-Sébastien Hoffmann, Christophe Cazaux Mol Pharmacol 2001 topics set
New tests for syphilis: rational design of a PCR method for detection of Treponema pallidum in clinical specimens using unique regions of the DNA polymerase I gene. Huanting Liu, B Rodes, C Y Chen, B Steiner J Clin Microbiol 2001 new
Characterization of the bacteriophage phi29-encoded protein p16.7: a membrane protein involved in phage DNA replication. Wilfried J J Meijer, A Serna-Rico, Margarita Salas Molecular microbiology 2001 pols set
Effects of benzo[a]pyrene DNA adducts on Escherichia coli DNA polymerase I (Klenow fragment) primer-template interactions: evidence for inhibition of the catalytically active ternary complex formation. Yuriy O Alekseyev, Leonid Dzantiev, Louis J Romano Biochemistry 2001 pols set
DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes. Xianmin Zeng, D B Winter, Cynthia Kasmer, K H Kraemer, Alan R Lehmann, Patricia J Gearhart Nat Immunol 2001 new
Requirement of DNA polymerase eta for error-free bypass of UV-induced CC and TC photoproducts. Sung-Lim Yu, Robert E Johnson, Satya Prakash, Louise Prakash Molecular and cellular biology 2001 new
The stereoselective targeting of a specific enzyme-substrate complex is the molecular mechanism for the synergic inhibition of HIV-1 reverse transcriptase by (R)-(-)-PPO464: a novel generation of nonnucleoside inhibitors. Giovanni Maga, Anna Ramunno, Vito Nacci, Giada A Locatelli, Silvio Spadari, Isabella Fiorini, Fausto Baldanti, Stefania Paolucci, Maurizio Zavattoni, Alberto Bergamini, Bruno Galletti, S Muck, Ulrich Hubscher, Gianluca Giorgi, G Guiso, S Caccia, Giuseppe Campiani The Journal of biological chemistry 2001 pols set
The emergence of different resistance mechanisms toward nucleoside inhibitors is explained by the properties of the wild type HIV-1 reverse transcriptase. Catherine Isel, Chantal Ehresmann, P Walter, Bernard Ehresmann, Roland Marquet The Journal of biological chemistry 2001 complete Roland Marquet*
Terminal deoxynucleotidyl transferase indiscriminately incorporates ribonucleotides and deoxyribonucleotides. J B Boulé, F Rougeon, C Papanicolaou The Journal of biological chemistry 2001 partial results
The (I/Y)XGG motif of adenovirus DNA polymerase affects template DNA binding and the transition from initiation to elongation. Arjan B Brenkman, M R Heideman, Verónica Truniger, Margarita Salas, Peter C van der Vliet The Journal of biological chemistry 2001 pols set
Anti-HIV-1 activity in vitro of ceftazidime degradation products. R Hobi, Ulrich Hübscher, K Neftel, E Alteri, B Poncioni, M R Walker, K Woods-Cook, P Schneider, J K Lazdins Antiviral chemistry & chemotherapy 2001 pols set
Mechanism of action of 1-beta-D-2,6-diaminopurine dioxolane, a prodrug of the human immunodeficiency virus type 1 inhibitor 1-beta-D-dioxolane guanosine. Phillip A Furman, J Jeffrey, L L Kiefer, Joy Y Feng, Karen S Anderson, K Borroto-Esoda, E Hill, William C Copeland, Chung K Chu, J P Sommadossi, I Liberman, Raymond F Schinazi, George R Painter Antimicrobial agents and chemotherapy 2001 pols set
In vitro analysis of human immunodeficiency virus type 1 minus-strand strong-stop DNA synthesis and genomic RNA processing. M D Driscoll, Marie-Pierre Golinelli, Stephen H Hughes Journal of virology 2001 pols set
The novel function of a short region K253xRxxxD259 conserved in the exonuclease domain of hyperthermostable DNA polymerase I from Pyrococcus horikoshii. R Zheng, Eriko Matsui, Yulong Shen, K V Musti, Y Feng, S Darnis, Y Kawarabayasi, H Kikuchi, K Harata, Ikuo Matsui Extremophiles 2001 pols set
Biochemical characterization of human DNA polymerase iota provides clues to its biological function. Agnès Tissier, Ekaterina G Frank, John P McDonald, Alexandra Vaisman, A R Fernàndez de Henestrosa, François Boudsocq, M P McLenigan, Roger Woodgate Biochem Soc Trans 2001 pols set
Comparison between Taq DNA polymerase and its Stoffel fragment for quantitative real-time PCR with hybridization probes. Jochen Wilhelm, Alfred Pingoud, Meinhard Hahn BioTechniques 2001 pols set
Cross-linking of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase to template-primer. Elena N Peletskaya, Paul L Boyer, Alex A Kogon, Patrick K Clark, Heiko Kroth, Jane M Sayer, Donald M Jerina, Stephen H Hughes Journal of virology 2001 pols set
Self-priming of retroviral minus-strand strong-stop DNAs. Marie-Pierre Golinelli, Stephen H Hughes Virology 2001 new
Physical and functional interactions of human DNA polymerase eta with PCNA. Lajos Haracska, Robert E Johnson, Ildiko Unk, B Phillips, Jerard Hurwitz, Louise Prakash, Satya Prakash Molecular and cellular biology 2001 pols set
Molecular dynamics of HIV-1 reverse transcriptase indicates increased flexibility upon DNA binding. M Madrid, J A Lukin, J D Madura, Jianping Ding, Edward Arnold Proteins 2001 pols set
Mutations in human DNA polymerase eta motif II alter bypass of DNA lesions. Eitan Glick, Kellie L Vigna, Lawrence A Loeb The EMBO journal 2001 complete Lawrence A Loeb*
SOS mutator DNA polymerase IV functions in adaptive mutation and not adaptive amplification. G J McKenzie, P L Lee, M J Lombardo, P J Hastings, Susan M Rosenberg Molecular cell 2001 new
Stimulation of DNA polymerase alpha activity by cdk2-phosphorylated Rb protein. Masaharu Takemura, Taichi Yamamoto, Masatoshi Kitagawa, Y Taya, Tetsu Akiyama, Hitomi Asahara, Stuart Linn, S Suzuki, Katsuyuki Tamai, Shonen Yoshida Biochem Biophys Res Commun 2001 new
The effect of DNA structure on the catalytic efficiency and fidelity of human DNA polymerase beta on templates with platinum-DNA adducts. Alexandra Vaisman, M W Warren, Stephen G Chaney The Journal of biological chemistry 2001 pols set
5'-Deoxyribose phosphate lyase activity of human DNA polymerase iota in vitro. Katarzyna Bebenek, Agnès Tissier, Ekaterina G Frank, John P McDonald, Rajendra Prasad, Samuel H Wilson, Roger Woodgate, Thomas A Kunkel Science 2001 pols set
Fluorescence-based DNA polymerase assay. H Tveit, T Kristensen Anal Biochem 2001 new
Galactosyldiacylglycerol, a mammalian DNA polymerase alpha-specific inhibitor from a sea alga, Petalonia bingbamiae. Yoshiyuki Mizushina, Yuichi Sugiyama, Hiromi Yoshida, Shinya Hanashima, Takayuki Yamazaki, Shinji Kamisuki, Keisuke Ohta, Masaharu Takemura, Tsuyoshi Yamaguchi, Akio Matsukage, Shonen Yoshida, Mineo Saneyoshi, Fumio Sugawara, K Sakagauchi Biol Pharm Bull 2001 pols set
Evading the proofreading machinery of a replicative DNA polymerase: induction of a mutation by an environmental carcinogen. R A Perlow, Suse Broyde Journal of molecular biology 2001 complete Suse Broyde*
The Lys103Asn mutation of HIV-1 RT: a novel mechanism of drug resistance. Y Hsiou, Jianping Ding, Kalyan Das, Arthur D Clark, Paul L Boyer, Paul Lewi, Paul A J Janssen, Jörg-Peter Kleim, M Rösner, Stephen H Hughes, Edward Arnold Journal of molecular biology 2001 topics set
Exonuclease proofreading by human mitochondrial DNA polymerase. Allison A Johnson, Kenneth A Johnson The Journal of biological chemistry 2001 new
Emerging links between hypermutation of antibody genes and DNA polymerases. Patricia J Gearhart, Richard D Wood Nature reviews. Immunology 2001 complete Joshua Mazzola
Interplay of clamp loader subunits in opening the beta sliding clamp of Escherichia coli DNA polymerase III holoenzyme. F P Leu, Mike E O'Donnell The Journal of biological chemistry 2001 pols set
Eukaryotic DNA polymerases: proposal for a revised nomenclature. Peter M J Burgers, Eugene V Koonin, E Bruford, Luis Blanco, K C Burtis, Michael F Christman, William C Copeland, Errol C Friedberg, Fumio Hanaoka, David C Hinkle, Christopher W Lawrence, Makoto Nakanishi, Haruo Ohmori, Louise Prakash, Satya Prakash, Claude-Agnès Reynaud, Akio Sugino, T Todo, Zhengqiang Wang, Jean-Claude Weill, Roger Woodgate The Journal of biological chemistry 2001 new
2-Amino-6-arylsulfonylbenzonitriles as non-nucleoside reverse transcriptase inhibitors of HIV-1. Joseph H Chan, J S Hong, R N Hunter , G F Orr, Jill R Cowan, D B Sherman, S M Sparks, B E Reitter, C Webster Andrews, Richard J Hazen, M St Clair, Lawrence R Boone, Robert G Ferris, Katrina L Creech, Grace B Roberts, Steven A Short, Kurt L Weaver, R J Ott, Jingshan Ren, A Hopkins, David I Stuart, David K Stammers J Med Chem 2001 topics set
A DNA polymerase beta mutator mutant with reduced nucleotide discrimination and increased protein stability. Amit M Shah, D A Conn, Shu-Xia Li, A Capaldi, J Jäger, Joann B Sweasy Biochemistry 2001 new
Crystal structure of the processivity clamp loader gamma (gamma) complex of E. coli DNA polymerase III. David Jeruzalmi, Mike E O'Donnell, John Kuriyan Cell 2001 topics set
DNA polymerase beta: pre-steady-state kinetic analyses of dATP alpha S stereoselectivity and alteration of the stereoselectivity by various metal ions and by site-directed mutagenesis. Jianhua Liu, Ming-Daw Tsai Biochemistry 2001 new
Role of the C-terminal residue of the DNA polymerase of bacteriophage T7. Jaya K Kumar, Stanley Tabor, Charles C Richardson The Journal of biological chemistry 2001 new
Accuracy of lesion bypass by yeast and human DNA polymerase eta. M Todd Washington, Robert E Johnson, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2001 pols set
Essential role of Sna41/Cdc45 in loading of DNA polymerase alpha onto minichromosome maintenance proteins in fission yeast. M Uchiyama, D Griffiths, K Arai, H Masai The Journal of biological chemistry 2001 new
Multiple regions of subunit interaction in Drosophila mitochondrial DNA polymerase: three functional domains in the accessory subunit. Li Fan, Laurie S Kaguni Biochemistry 2001 new
Translesion DNA synthesis by yeast DNA polymerase eta on templates containing N2-guanine adducts of 1,3-butadiene metabolites. Irina G Minko, M Todd Washington, Louise Prakash, Satya Prakash, R Stephen Lloyd The Journal of biological chemistry 2001 new
DNA structure and aspartate 276 influence nucleotide binding to human DNA polymerase beta. Implication for the identity of the rate-limiting conformational change. Brian J Vande Berg, William A Beard, Samuel H Wilson The Journal of biological chemistry 2001 pols set
Insights into the molecular mechanism of mitochondrial toxicity by AIDS drugs. Joy Y Feng, Allison A Johnson, Kenneth A Johnson, Karen S Anderson The Journal of biological chemistry 2001 new
Mitochondrial dna depletion, oxidative stress, and mutation: mechanisms of dysfunction from nucleoside reverse transcriptase inhibitors. William Lewis, William C Copeland, Brian J Day Laboratory investigation; a journal of technical methods and pathology 2001 new
Optimal conditions to use Pfu exo(-) DNA polymerase for highly efficient ligation-mediated polymerase chain reaction protocols. M Angers, J F Cloutier, A Castonguay, R Drouin Nucleic acids research 2001 new
Tau binds and organizes Escherichia coli replication proteins through distinct domains. Domain III, shared by gamma and tau, binds delta delta ' and chi psi. D Gao, Charles S McHenry The Journal of biological chemistry 2001 new
[Expression and drug resistance of human MGMT gene in hemopoietic cells mediated by bicistronic retroviral vector]. Jide Wang, X Xia, Zhu Chen, C G Ruan Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 2001 new
DNA polymerase beta is not essential for the formation of palindromic (P) region of T cell receptor gene. H Gonda, M Sugai, T Katakai, Noriyuki Sugo, Yasuaki Aratani, Hideki Koyama, K J Mori, A Shimizu Immunol Lett 2001 new
Bacteriophage T4 RNase H removes both RNA primers and adjacent DNA from the 5' end of lagging strand fragments. M Bhagwat, Nancy G Nossal The Journal of biological chemistry 2001 complete
The basic loop of the RNase H domain of MLV RT is important both for RNase H and for polymerase activity. Paul L Boyer, Hong Qiang Gao, P Frank, Patrick K Clark, Stephen H Hughes Virology 2001 pols set
Replication of phenotypically mixed human immunodeficiency virus type 1 virions containing catalytically active and catalytically inactive reverse transcriptase. John G Julias, Andrea L Ferris, Paul L Boyer, Stephen H Hughes Journal of virology 2001 new
The ribonuclease H activity of the reverse transcriptases of human immunodeficiency viruses type 1 and type 2 is affected by the thumb subdomain of the small protein subunits. Z Sevilya, S Loya, Stephen H Hughes, A Hizi Journal of molecular biology 2001 pols set
Solution structure of a viral DNA polymerase X and evidence for a mutagenic function. Alexander K Showalter, I J Byeon, Mei-I Su, Ming-Daw Tsai Nature structural biology 2001 partial results
Evolution of anti-HIV drug candidates. Part 2: Diaryltriazine (DATA) analogues. Donald W Ludovici, Robert W Kavash, Michael J Kukla, Chih Y Ho, Hong Ye, B L De Corte, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, H E Moereels, Jan Heeres, Lucien M H Koymans, Marc R De Jonge, Koen J A Van Aken, Frits F D Daeyaert, Paul J Lewi, Kalyan Das, Edward Arnold, Paul A J Janssen Bioorganic & medicinal chemistry letters 2001 pols set
Linear diffusion on DNA despite high-affinity binding by a DNA polymerase processivity factor. John C W Randell, Donald M Coen Molecular cell 2001 new
Purification and properties of Aquifex aeolicus DNA polymerase expressed in Escherichia coli. J R Chang, Jeong Jin Choi, H K Kim, Suk-Tae Kwon FEMS Microbiol Lett 2001 new
DNA polymerase beta mediates protection of mammalian cells against ganciclovir-induced cytotoxicity and DNA breakage. M T Tomicic, R Thust, Robert W Sobol, Bernd Kaina Cancer research 2001 new
Characterization of the DNA polymerase gene of varicella-zoster viruses resistant to acyclovir. T Kamiyama, M Kurokawa, K Shiraki The Journal of general virology 2001 new
HIV-1 reverse transcriptase mutations found in a drug-experienced patient confer reduced susceptibility to multiple nucleoside reverse transcriptase inhibitors. J E Fitzgibbon, B DiCola, Edward Arnold, Kalyan Das, B E Sha, J C Pottage, R Nahass, S Gaur, J F John Antiviral therapy 2001 pols set
Evolution of anti-HIV drug candidates. Part 1: From alpha-anilinophenylacetamide (alpha-APA) to imidoyl thiourea (ITU). Donald W Ludovici, Michael J Kukla, P G Grous, S Krishnan, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, Erik De Clercq, Edward Arnold, Paul A J Janssen Bioorganic & medicinal chemistry letters 2001 pols set
Lesion bypass by the Escherichia coli DNA polymerase V requires assembly of a RecA nucleoprotein filament. N B Reuven, Gali Arad, A Z Stasiak, A Stasiak, Zvi Livneh The Journal of biological chemistry 2001 pols set
Crystal structure of DNA polymerase from hyperthermophilic archaeon Pyrococcus kodakaraensis KOD1. Hiroshi Hashimoto, Motomu Nishioka, Shinsuke Fujiwara, Masahiro Takagi, Tadayuki Imanaka, Tsuyoshi Inoue, Yasushi Kai Journal of molecular biology 2001 topics set
A complex of the bacteriophage T7 primase-helicase and DNA polymerase directs primer utilization. Masato Kato, David N Frick, Joonsoo Lee, Stanley Tabor, Charles C Richardson, Tom Ellenberger The Journal of biological chemistry 2001 new
Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma. Susan E Lim, William C Copeland The Journal of biological chemistry 2001 pols set
Identification, transcription and sequence analysis of the Spodoptera littoralis nucleopolyhedrovirus (SpliNPV) DNA polymerase gene. J Huang, D B Levin Arch Virol 2001 new
Transcriptional regulation of the human DNA polymerase delta catalytic subunit gene POLD1 by p53 tumor suppressor and Sp1. B Li, Marietta Y W T Lee The Journal of biological chemistry 2001 pols set
Expression, purification and characterization of the Spodoptera littoralis nucleopolyhedrovirus (SpliNPV) DNA polymerase and interaction with the SpliNPV non-hr origin of DNA replication. J Huang, D B Levin The Journal of general virology 2001 new
Identification of an intrinsic 5'-deoxyribose-5-phosphate lyase activity in human DNA polymerase lambda: a possible role in base excision repair. Miguel García-Díaz, Katarzyna Bebenek, Thomas A Kunkel, Luis Blanco The Journal of biological chemistry 2001 pols set
Multiple phosphorylation sites of DNA polymerase alpha-primase cooperate to regulate the initiation of DNA replication in vitro. O Schub, G Rohaly, Richard W P Smith, A Schneider, S Dehde, I Dornreiter, Heinz Peter Nasheuer The Journal of biological chemistry 2001 new
[Reagents for modification of protein-nucleic acids complexes. II. Site-specific photomodification of DNA-polymerase beta complexes with primers elongated by the dCTP exo-N-substituted arylazido derivatives]. I A Drachkova, Irina O Petruseva, I V Safronov, A L Zakharenko, G V Shishkin, Olga I Lavrik, Svetlana N Khodyreva Bioorg Khim 2001 new
Arg660Ser mutation in Thermus aquaticus DNA polymerase I suppresses T-->C transitions: implication of wobble base pair formation at the nucleotide incorporation step. K Yoshida, A Tosaka, Hiroyuki Kamiya, Takashi Murate, Hironori Kasai, Y Nimura, Masanori Ogawa, Shonen Yoshida, Motoshi Suzuki Nucleic acids research 2001 pols set
Interaction of loach DNA polymerase delta with DNA duplexes with single-strand gaps. N P Sharova, E B Abramova, S B Dmitrieva, D D Dimitrova, V S Mikhailov Biochemistry (Mosc) 2001 new
The role of DNA polymerase activity in human non-homologous end joining. Helmut Pospiech, Anna K Rytkönen, Juhani E Syväoja Nucleic acids research 2001 new
Carboxyl-terminal domain III of the delta' subunit of the DNA polymerase III holoenzyme binds delta. Min-Sun Song, H Garry Dallmann, Charles S McHenry The Journal of biological chemistry 2001 new
DNA polymerase beta is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extracts. Sarah L Allinson, Irina I Dianova, Grigory L Dianov The EMBO journal 2001 new
Fidelity and damage bypass ability of Schizosaccharomyces pombe Eso1 protein, comprised of DNA polymerase eta and sister chromatid cohesion protein Ctf7. A C Madril, Robert E Johnson, M Todd Washington, Louise Prakash, Satya Prakash The Journal of biological chemistry 2001 new
Amplification of the DNA polymerase I gene of Treponema pallidum from whole blood of persons with syphilis. A A Marfin, Huanting Liu, M Y Sutton, B Steiner, A Pillay, L E Markowitz Diagn Microbiol Infect Dis 2001 new
Interaction with PCNA is essential for yeast DNA polymerase eta function. Lajos Haracska, Christine M Kondratick, Ildiko Unk, Satya Prakash, Louise Prakash Molecular cell 2001 new
The carboxyl terminal sequence of nucleolar protein B23.1 is important in its DNA polymerase alpha-stimulatory activity. H Umekawa, K Sato, Masaharu Takemura, Yoh Watanabe, S Usui, Tomonori Takahashi, Shonen Yoshida, M O Olson, Yasuhiro Furuichi J Biochem 2001 new
DNA polymerase beta -mediated long patch base excision repair. Poly(ADP-ribose)polymerase-1 stimulates strand displacement DNA synthesis. Rajendra Prasad, Olga I Lavrik, Soon-Jong Kim, Padmini Kedar, Xiao-Ping Yang, Brian J Vande Berg, Samuel H Wilson The Journal of biological chemistry 2001 new
Decreased frequency of somatic hypermutation and impaired affinity maturation but intact germinal center formation in mice expressing antisense RNA to DNA polymerase zeta. Marilyn Diaz, Laurent K Verkoczy, M F Flajnik, Norman R Klinman J Immunol 2001 new
Human DNA polymerase iota promiscuous mismatch extension. Alexandra Vaisman, Agnès Tissier, Ekaterina G Frank, Myron F Goodman, Roger Woodgate The Journal of biological chemistry 2001 pols set
Inhibition of hepatitis B virus DNA replication by imino sugars without the inhibition of the DNA polymerase: therapeutic implications. A Mehta, S Carrouée, B Conyers, R Jordan, T Butters, R A Dwek, T M Block Hepatology 2001 new
The DNA polymerase delta promoter from Plasmodium falciparum contains an unusually long 5' untranslated region and intrinsic DNA curvature. M E Porter Mol Biochem Parasitol 2001 new
The HIV-1 transactivator protein Tat is a potent inducer of the human DNA repair enzyme beta-polymerase. Deepak K Srivastava, C L Tendler, D Milani, M A English, J D Licht, Samuel H Wilson AIDS (London, England) 2001 new
Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors. Jingshan Ren, C Nichols, L Bird, P Chamberlain, Kurt L Weaver, S Short, David I Stuart, David K Stammers Journal of molecular biology 2001 topics set
Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells. Patricia L Kannouche, Bernard C Broughton, M Volker, Fumio Hanaoka, Leon H F Mullenders, Alan R Lehmann Genes Dev 2001 new
Synthesis and properties of oligonucleotides containing 5-formyl-2'-deoxycytidine: in vitro DNA polymerase reactions on DNA templates containing 5-formyl-2'-deoxycytidine. N Karino, Y Ueno, Akira Matsuda Nucleic acids research 2001 pols set
Mechanism of DNA polymerase II-mediated frameshift mutagenesis. Olivier J Becherel, Robert P P Fuchs Proceedings of the National Academy of Sciences of the United States of America 2001 new
A type IB topoisomerase with DNA repair activities. G I Belova, Rajendra Prasad, S A Kozyavkin, J A Lake, Samuel H Wilson, A I Slesarev Proceedings of the National Academy of Sciences of the United States of America 2001 new
Mutations at amino acid positions 63, 189, and 396 of human immunodeficiency virus type 1 reverse transcriptase (RT) partially restore the DNA polymerase activity of a Trp229Tyr mutant RT. H Pelemans, Robert Esnouf, K L Min, M Parniak, Erik De Clercq, Jan Balzarini Virology 2001 pols set
Identification of a novel family of nucleosides that specifically inhibit HIV-1 reverse transcriptase. Cristina Chamorro, Esther Lobatón, María-Cruz Bonache, Erik De Clercq, Jan Balzarini, Sonsoles Velázquez, Ana San-Félix, María-José Camarasa Bioorganic & medicinal chemistry letters 2001 pols set
Rapid alternation of drug therapy is highly efficient in suppressing the emergence of mutant drug-resistant HIV strains in cell culture. Jan Balzarini, Erik De Clercq AIDS research and human retroviruses 2001 pols set
Synthesis, biological activity, pharmacokinetic properties and molecular modelling studies of novel 1H,3H-oxazolo[3,4-a]benzimidazoles: non-nucleoside HIV-1 reverse transcriptase inhibitors. Alba Chimirri, Pietro Monforte, Angela Rao, Maria Zappalà, Anna-Maria Monforte, G De Sarro, Christophe Pannecouque, Myriam Witvrouw, Jan Balzarini, Erik De Clercq Antiviral chemistry & chemotherapy 2001 pols set
Mismatch extension ability of yeast and human DNA polymerase eta. M Todd Washington, Robert E Johnson, Satya Prakash, Louise Prakash The Journal of biological chemistry 2001 pols set
Hamao Umezawa Memorial Award Lecture: "An Odyssey in the Viral Chemotherapy Field". Erik De Clercq International journal of antimicrobial agents 2001 new
Directed evolution of polymerase function by compartmentalized self-replication. Farid J Ghadessy, J L Ong, Philipp Holliger Proceedings of the National Academy of Sciences of the United States of America 2001 pols set
Intron conservation in the DNA polymerase gene encoded by Chlorella viruses. Yongqing Zhang, B Adams, Lanying Sun, D E Burbank, J L Van Etten Virology 2001 new
4'-Ethynyl nucleoside analogs: potent inhibitors of multidrug-resistant human immunodeficiency virus variants in vitro. Ei-Ichi Kodama, Satoru Kohgo, Kenji Kitano, H Machida, Hiroyuki Gatanaga, S Shigeta, Masao Matsuoka, Hiroshi Ohrui, Hiroyuki Mitsuya Antimicrob Agents Chemother 2001 new
Reverse transcription slippage over the mRNA secondary structure of the LIP1 gene. Y J Zhang, H Y Pan, S J Gao BioTechniques 2001 new
Mutation of POLG is associated with progressive external ophthalmoplegia characterized by mtDNA deletions. Gert Van Goethem, Bart Dermaut, Ann Löfgren, Jean-Jacques Martin, Christine Van Broeckhoven Nature genetics 2001 pols set
New developments in anti-HIV chemotherapy. Erik De Clercq Current medicinal chemistry 2001 pols set
Prevalence of genotypic resistance among antiretroviral drug-naive HIV-1-infected patients in Belgium. K Van Vaerenbergh, L Debaisieux, N De Cabooter, C Declercq, K Desmet, K Fransen, B Maes, D Marissens, K Miller, G Muyldermans, S Sprecher, L Stuyver, D Vaira, C Verhofstede, G Zissis, M Van Ranst, Erik De Clercq, J Desmyter, Anne-Mieke Vandamme Antiviral therapy 2001 new
1H, 15N, and 13C resonance assignments for a 20 kDa DNA polymerase from African swine fever virus. Mark W Maciejewski, B Pan, R Shin, A Denninger, Gregory P Mullen J Biomol NMR 2001 new
A tumor necrosis factor alpha- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase delta and proliferating cell nuclear antigen. H He, Cheng-Keat Tan, Kathleen M Downey, Antero G So Proceedings of the National Academy of Sciences of the United States of America 2001 new
DNA lesion bypass polymerases open up. William A Beard, Samuel H Wilson Structure (London, England : 1993) 2001 new
Direct monitoring kinetic studies of DNA polymerase reactions on a DNA-immobilized quartz-crystal microbalance. H Matsuno, K Niikura, Y Okahata Chemistry 2001 pols set
Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain. S Najmudin, Marie L Coté, D Sun, S Yohannan, Sherwin P Montano, J Gu, Millie M Georgiadis Journal of molecular biology 2000 topics set
Intrinsic polymerase activities of UmuD'(2)C and MucA'(2)B are responsible for their different mutagenic properties during bypass of a T-T cis-syn cyclobutane dimer. Paul I O'Grady, Angela Borden, Dominique Vandewiele, A Ozgenc, Roger Woodgate, Christopher W Lawrence Journal of bacteriology 2000 new
The putative coiled coil domain of the phi 29 terminal protein is a major determinant involved in recognition of the origin of replication. A Serna-Rico, B Illana, Margarita Salas, Wilfried J J Meijer The Journal of biological chemistry 2000 pols set
MDM2 interacts with the C-terminus of the catalytic subunit of DNA polymerase epsilon. Nikolina Vlatkovic, S Guerrera, Yingqian Li, Stuart Linn, Dale S Haines, Mark T Boyd Nucleic acids research 2000 new
Carboxy terminal region of a chloroplast DNA polymerase accessory factor stimulates DNA polymerase activity. A Gaikwad, D Van Hop, Sunil K Mukherjee Indian J Biochem Biophys 2000 new
A conformational change in E. coli DNA polymerase I (Klenow fragment) is induced in the presence of a dNTP complementary to the template base in the active site. Leonid Dzantiev, Louis J Romano Biochemistry 2000 pols set
In vitro concatemer formation catalyzed by vaccinia virus DNA polymerase. David O Willer, X D Yao, M J Mann, David H Evans Virology 2000 complete David H Evans*
A direct interaction between proliferating cell nuclear antigen (PCNA) and Cdk2 targets PCNA-interacting proteins for phosphorylation. Stéphane Koundrioukoff, Z O Jónsson, Sameez Hasan, R N de Jong, Peter C van der Vliet, Michael O Hottiger, Ulrich Hübscher The Journal of biological chemistry 2000 new
Plasmodium falciparum clones resistant to (S)-9-(3-hydroxy-2-phosphonylmethoxy-propyl)adenine carry amino acid substitutions in DNA polymerase delta. L J Smeijsters, N M Zijlstra, J Veenstra, B E Verstrepen, C Heuvel, J P Overdulve, E de Vries Mol Biochem Parasitol 2000 new
Analysis of mutations at positions 115 and 116 in the dNTP binding site of HIV-1 reverse transcriptase. Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes Proceedings of the National Academy of Sciences of the United States of America 2000 new
Effects of amino acid substitutions at position 115 on the fidelity of human immunodeficiency virus type 1 reverse transcriptase. Paul L Boyer, Stephen H Hughes Journal of virology 2000 pols set
A novel DNA-binding protein associated with DNA polymerase-alpha in pea stimulates polymerase activity on infrequently primed templates. J A Bryant, D C Brice, P N Fitchett, L E Anderson J Exp Bot 2000 new
Base stacking and even/odd behavior of hairpin loops in DNA triplet repeat slippage and expansion with DNA polymerase. Michael J Hartenstine, Myron F Goodman, John Petruska The Journal of biological chemistry 2000 new
Replication past O(6)-methylguanine by yeast and human DNA polymerase eta. Lajos Haracska, Satya Prakash, Louise Prakash Molecular and cellular biology 2000 pols set
Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions. Robert E Johnson, M Todd Washington, Lajos Haracska, Satya Prakash, Louise Prakash Nature 2000 topics set
Kinetic analysis of nucleotide incorporation by mammalian DNA polymerase delta. H J Einolf, F Peter Guengerich The Journal of biological chemistry 2000 partial results
NMR solution structure of the theta subunit of DNA polymerase III from Escherichia coli. Max A Keniry, H A Berthon, Ji Yeon Yang, C S Miles, Nicholas E Dixon Protein science : a publication of the Protein Society 2000 topics set
Transcription of the catalytic 180-kDa subunit gene of mouse DNA polymerase alpha is controlled by E2F, an Ets-related transcription factor, and Sp1. M Izumi, Masayuki Yokoi, N S Nishikawa, Hiroshi Miyazawa, Akio Sugino, M Yamagishi, Masamitsu Yamaguchi, Akio Matsukage, F Yatagai, Fumio Hanaoka Biochimica et biophysica acta 2000 new
Role of glutamine 151 of human immunodeficiency virus type-1 reverse transcriptase in substrate selection as assessed by site-directed mutagenesis. Neerja Kaushik, T T Talele, P K Pandey, D Harris, P N Yadav, V N Pandey Biochemistry 2000 pols set
Visualization of two binding sites for the Escherichia coli UmuD'(2)C complex (DNA pol V) on RecA-ssDNA filaments. Ekaterina G Frank, N Cheng, C C Do, M E Cerritelli, Irina Bruck, Myron F Goodman, E H Egelman, Roger Woodgate, A C Steven Journal of molecular biology 2000 new
Error-prone lesion bypass by human DNA polymerase eta. Yongqing Zhang, Fenghua Yuan, Xiaoming Wu, Olga Rechkoblit, John-Stephen Taylor, Nicholas E Geacintov, Zhengqiang Wang Nucleic acids research 2000 pols set
Phylogenetic position of the Diadromus pulchellus ascovirus DNA polymerase among viruses with large double-stranded DNA genomes. K Stasiak, M V Demattei, B A Federici, Y Bigot The Journal of general virology 2000 new
In vitro replication of primer-templates containing benzo[a]pyrene adducts by exonuclease-deficient Escherichia coli DNA polymerase I (Klenow fragment): effect of sequence context on lesion bypass. Yuriy O Alekseyev, Louis J Romano Biochemistry 2000 pols set
Non-nucleoside HIV-1 reverse transcriptase inhibitors: synthesis and biological evaluation of novel quinoxalinylethylpyridylthioureas as potent antiviral agents. Giuseppe Campiani, M Fabbrini, Elena Morelli, Vito Nacci, Giovanni Greco, Ettore Novellino, Giovanni Maga, Silvio Spadari, Alberto Bergamini, E Faggioli, I Uccella, F Bolacchi, Stefano Marini, Massimo Coletta, C Fracasso, S Caccia Antiviral chemistry & chemotherapy 2000 pols set
Accuracy of thymine-thymine dimer bypass by Saccharomyces cerevisiae DNA polymerase eta. M Todd Washington, Robert E Johnson, Satya Prakash, Louise Prakash Proceedings of the National Academy of Sciences of the United States of America 2000 pols set
A sensitive scanning technology for low frequency nuclear point mutations in human genomic DNA. X C Li-Sucholeiki, William G Thilly Nucleic acids research 2000 topics set
Human immunodeficiency virus type 1 nucleocapsid protein can prevent self-priming of minus-strand strong stop DNA by promoting the annealing of short oligonucleotides to hairpin sequences. M D Driscoll, Stephen H Hughes Journal of virology 2000 new
Thermostable DNA polymerase from Thermus thermophilus B35: influence of divalent metal ions on the interaction with deoxynucleoside triphosphates. Nadejda I Rechkunova, S S Okhapkina, Rashid O Anarbaev, I A Lokhova, S K Degtyarev, Olga I Lavrik Biochemistry (Mosc) 2000 new
Kinetic analysis of Sp1-mediated transcriptional activation of a TATA-containing promoter. Satya Narayan, Samuel H Wilson Biochemistry 2000 new
Evidence that DNA polymerase delta isolated by immunoaffinity chromatography exhibits high-molecular weight characteristics and is associated with the KIAA0039 protein and RPA. J Mo, Lingfeng Liu, A Leon, Nayef Mazloum, Marietta Y W T Lee Biochemistry 2000 new
HIV-1 reverse transcriptase (RT) genotype and susceptibility to RT inhibitors during abacavir monotherapy and combination therapy. V Miller, M Ait-Khaled, C Stone, P Griffin, D Mesogiti, A Cutrell, R Harrigan, Schlomo Staszewski, C Katlama, G Pearce, M Tisdale Aids 2000 new
Vertical-scanning mutagenesis of a critical tryptophan in the "minor groove binding track" of HIV-1 reverse transcriptase. Major groove DNA adducts identify specific protein interactions in the minor groove. G J Latham, E Forgacs, William A Beard, Rajendra Prasad, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson, R Stephen Lloyd The Journal of biological chemistry 2000 pols set
The human DINB1 gene encodes the DNA polymerase Poltheta. Robert E Johnson, Satya Prakash, Louise Prakash Proceedings of the National Academy of Sciences of the United States of America 2000 partial results
The biochemical basis and in vivo regulation of SOS-induced mutagenesis promoted by Escherichia coli DNA polymerase V (UmuD'2C). Myron F Goodman, Roger Woodgate Cold Spring Harbor symposia on quantitative biology 2000 pols set
EBV DNA polymerase inhibition of tannins from Eugenia uniflora. M H Lee, J F Chiou, K Y Yen, L L Yang Cancer Lett 2000 pols set
Human DNA polymerase kappa: a novel DNA polymerase of unknown biological function encoded by the DINB1 gene. Valerie L Gerlach, William J Feaver, Paula L Fischhaber, James A Richardson, L Aravind, Eugene V Koonin, Katarzyna Bebenek, Thomas A Kunkel, Errol C Friedberg Cold Spring Harbor symposia on quantitative biology 2000 pols set
Characterization of a catalytically slow AP lyase activity in DNA polymerase gamma and other family A DNA polymerases. Kevin G Pinz, Daniel F Bogenhagen The Journal of biological chemistry 2000 new
Mode analysis of binding of fatty acids to mammalian DNA polymerases. Yoshiyuki Mizushina, M Sagisaka, H Sakaib, M Abeb, Kengo Sakaguchi Biochimica et biophysica acta 2000 new
Pol kappa: A DNA polymerase required for sister chromatid cohesion. Zhengqiang Wang, Irene B Castaño, A De Las Peñas, Carrie Adams, Michael F Christman Science 2000 new
Human DNA polymerase kappa synthesizes DNA with extraordinarily low fidelity. Yongqing Zhang, Fenghua Yuan, Hongkui Xin, Xiaoming Wu, D K Rajpal, D Yang, Zhengqiang Wang Nucleic acids research 2000 pols set
Phenotypic and genotypic resistance patterns of HIV-1 isolates derived from individuals treated with didanosine and stavudine. E P Coakley, J M Gillis, S M Hammer Aids 2000 new
Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene. Eiji Ohashi, Katarzyna Bebenek, Toshiro Matsuda, William J Feaver, Valerie L Gerlach, Errol C Friedberg, Haruo Ohmori, Thomas A Kunkel The Journal of biological chemistry 2000 partial results
Coupling ribose selection to fidelity of DNA synthesis. The role of Tyr-115 of human immunodeficiency virus type 1 reverse transcriptase. C E Cases-Gonzalez, M Gutierrez-Rivas, L Menéndez-Arias The Journal of biological chemistry 2000 new
The expanding polymerase universe. Myron F Goodman, Brigette Tippin Nat Rev Mol Cell Biol 2000 new
hTERT can function with rabbit telomerase RNA: regulation of gene expression and attenuation of apoptosis. Hua Xiang, Jin Wang, Ying-Wei Mao, David Wan-Cheng Li Biochemical and biophysical research communications 2000 new
Backbone dynamics and refined solution structure of the N-terminal domain of DNA polymerase beta. Correlation with DNA binding and dRP lyase activity. Mark W Maciejewski, D Liu, Rajendra Prasad, Samuel H Wilson, Gregory P Mullen Journal of molecular biology 2000 topics set
Universal PCR amplification of mouse immunoglobulin gene variable regions: the design of degenerate primers and an assessment of the effect of DNA polymerase 3' to 5' exonuclease activity. Zhengqiang Wang, M Raifu, M Howard, L Smith, D Hansen, R Goldsby, D Ratner Journal of immunological methods 2000 new
Misinsertion and bypass of thymine-thymine dimers by human DNA polymerase iota. Agnès Tissier, Ekaterina G Frank, John P McDonald, Shigenori Iwai, Fumio Hanaoka, Roger Woodgate The EMBO journal 2000 pols set
Inhibition of HIV-1 reverse transcriptase-catalyzed DNA strand transfer reactions by 4-chlorophenylhydrazone of mesoxalic acid. W R Davis, J Tomsho, S Nikam, E M Cook, D Somand, J A Peliska Biochemistry 2000 topics set
Analysis of O29 DNA polymerase by partial proteolysis: binding of terminal protein in the double-stranded DNA channel. Verónica Truniger, Luis Blanco, Margarita Salas Journal of molecular biology 2000 pols set
Diversity of hepatitis G virus within a single infected individual. L Shao, H Shinzawa, X Zhang, D B Smith, H Watanabe, H Mitsuhashi, K Saito, T Saito, H Togashi, Tomosaburo Takahashi Virus genes 2000 pols set
Role of the dinB gene product in spontaneous mutation in Escherichia coli with an impaired replicative polymerase. B S Strauss, R Roberts, L Francis, P Pouryazdanparast J Bacteriol 2000 new
Species specificity of human RPA in simian virus 40 DNA replication lies in T-antigen-dependent RNA primer synthesis. Michael Wang, J S Park, M Ishiai, Jerard Hurwitz, Sang Hee Lee Nucleic acids research 2000 new
Long-term exposure of HIV type 1-infected cell cultures to combinations of the novel quinoxaline GW420867X with lamivudine, abacavir, and a variety of nonnucleoside reverse transcriptase inhibitors. Jan Balzarini, Erik De Clercq, A Carbonez, V Burt, Jörg-Peter Kleim AIDS research and human retroviruses 2000 pols set
In vitro reconstitution of the Schizosaccharomyces pombe alternative excision repair pathway. J L Alleva, S Zuo, Jerard Hurwitz, P W Doetsch Biochemistry 2000 new
Dehydroaltenusin, a mammalian DNA polymerase alpha inhibitor. Yoshiyuki Mizushina, Shinji Kamisuki, Takeshi Mizuno, Masaharu Takemura, Hitomi Asahara, Stuart Linn, Tsuyoshi Yamaguchi, Akio Matsukage, Fumio Hanaoka, Shonen Yoshida, Mineo Saneyoshi, Fumio Sugawara, Kengo Sakaguchi The Journal of biological chemistry 2000 complete Takeshi Mizuno*
A novel human immunodeficiency virus type 1 reverse transcriptase mutational pattern confers phenotypic lamivudine resistance in the absence of mutation 184V. Kurt Hertogs, Stuart Bloor, V De Vroey, C van Den Eynde, Pascale Dehertogh, A van Cauwenberge, Martin Stürmer, T Alcorn, S Wegner, M van Houtte, V Miller, Brendan A Larder Antimicrob Agents Chemother 2000 topics set
DNA polymerase stalling, sister chromatid recombination and the BRCA genes. R Scully, Nadine Puget, K Vlasakova Oncogene 2000 pols set
Human immunodeficiency virus type 1 reverse transcriptase dimer destabilization by 1-[Spiro[4"-amino-2",2" -dioxo-1",2" -oxathiole-5",3'-[2', 5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]]]-3-ethylthy mine. Nicolas Sluis-Cremer, G I Dmitrienko, Jan Balzarini, María-José Camarasa, Michael A. Parniak Biochemistry 2000 pols set
Crystal structure of mammalian poly(A) polymerase in complex with an analog of ATP. G Martin, W Keller, Sylvie Doublié The EMBO journal 2000 complete W Keller*
Escherichia coli DNA polymerase IV mutator activity: genetic requirements and mutational specificity. Jérôme E Wagner, Takehiko Nohmi J Bacteriol 2000 complete Jérôme E Wagner*
Xeroderma pigmentosum variant: from a human genetic disorder to a novel DNA polymerase. Chikahide Masutani, Rika Kusumoto, Ayumi Yamada, M Yuasa, M Araki, T Nogimori, Masayuki Yokoi, Toshihiko Eki, Shigenori Iwai, Fumio Hanaoka Cold Spring Harbor symposia on quantitative biology 2000 new
Werner protein recruits DNA polymerase delta to the nucleolus. A M Szekely, Y H Chen, C Zhang, J Oshima, S M Weissman Proceedings of the National Academy of Sciences of the United States of America 2000 pols set
Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon. Yingqian Li, Zachary F Pursell, Stuart Linn The Journal of biological chemistry 2000 new
Nucleotide excision repair DNA synthesis by excess DNA polymerase beta: a potential source of genetic instability in cancer cells. Yvan Canitrot, Jean-Sébastien Hoffmann, P Calsou, Hiroshi Hayakawa, B Salles, Christophe Cazaux The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000 new
Drug resistance and drug combination features of the human immunodeficiency virus inhibitor, BCH-10652 [(+/-)-2'-deoxy-3'-oxa-4'-thiocytidine, dOTC]. D L Taylor, P S Ahmed, A S Tyms, L J Wood, L A Kelly, P Chambers, J Clarke, J Bedard, T L Bowlin, R F Rando Antiviral chemistry & chemotherapy 2000 pols set
Binding of the second generation non-nucleoside inhibitor S-1153 to HIV-1 reverse transcriptase involves extensive main chain hydrogen bonding. Jingshan Ren, C Nichols, Louise E Bird, Tsuyoshi Fujiwara, H Sugimoto, David I Stuart, David K Stammers The Journal of biological chemistry 2000 topics set
Human mitochondrial DNA polymerase holoenzyme: reconstitution and characterization. Allison A Johnson, Y c Tsai, S W Graves, Kenneth A Johnson Biochemistry 2000 new
Molecular mechanisms of HIV-1 resistance to nucleoside reverse transcriptase inhibitors (NRTIs). Nicolas Sluis-Cremer, Dominique Arion, Michael A. Parniak Cellular and molecular life sciences : CMLS 2000 pols set
Minor groove interactions at the DNA polymerase beta active site modulate single-base deletion error rates. Wendy P Osheroff, William A Beard, S Yin, Samuel H Wilson, Thomas A Kunkel The Journal of biological chemistry 2000 new
Human immunodeficiency virus type 1 mutations selected in patients failing efavirenz combination therapy. L T Bacheler, E D Anton, P Kudish, D Baker, J Bunville, K Krakowski, L Bolling, M Aujay, X V Wang, D Ellis, M F Becker, A L Lasut, H J George, D R Spalding, G Hollis, K Abremski Antimicrobial agents and chemotherapy 2000 pols set
Autonomous 3'-->5' exonucleases can proofread for DNA polymerase beta from rat liver. Igor V Shevelev, N V Belyakova, T P Kravetskaya, V M Krutyakov Mutation research 2000 partial results
Differential regulation of the catalytic and accessory subunit genes of Drosophila mitochondrial DNA polymerase. E Lefai, M A Fernandez-Moreno, A Alahari, Laurie S Kaguni, Rafael Garesse The Journal of biological chemistry 2000 new
poliota, a remarkably error-prone human DNA polymerase. Agnès Tissier, John P McDonald, Ekaterina G Frank, Roger Woodgate Genes & development 2000 topics set
Mechanisms of accurate translesion synthesis by human DNA polymerase eta. Chikahide Masutani, Rika Kusumoto, Shigenori Iwai, Fumio Hanaoka The EMBO journal 2000 pols set
Structure-activity relationship of a novel group of mammalian DNA polymerase inhibitors, synthetic sulfoquinovosylacylglycerols. Shinya Hanashima, Yoshiyuki Mizushina, Keisuke Ohta, Takayuki Yamazaki, Fumio Sugawara, Kengo Sakaguchi Jpn J Cancer Res 2000 pols set
Preferential incorporation of G opposite template T by the low-fidelity human DNA polymerase iota. Yongqing Zhang, Fenghua Yuan, Xiaoming Wu, Zhengqiang Wang Molecular and cellular biology 2000 partial results
Modulation of base excision repair by low density lipoprotein, oxidized low density lipoprotein and antioxidants in mouse monocytes. K H Chen, Deepak K Srivastava, R K Singhal, S Jacob, A E Ahmed, Samuel H Wilson Carcinogenesis 2000 new
Protection against methylation-induced cytotoxicity by DNA polymerase beta-dependent long patch base excision repair. Julie K Horton, Rajendra Prasad, E Hou, Samuel H Wilson The Journal of biological chemistry 2000 new
Multiple amino acid substitutions allow DNA polymerases to synthesize RNA. P H Patel, Lawrence A Loeb The Journal of biological chemistry 2000 topics set
Ribavirin and mycophenolic acid potentiate the activity of guanine- and diaminopurine-based nucleoside analogues against hepatitis B virus. Chunxiao Ying, Erik De Clercq, Johan Neyts Antiviral research 2000 new
Differential functional behavior of viral phi29, Nf and GA-1 SSB proteins. Irene Gascón, José María Lázaro, Margarita Salas Nucleic acids research 2000 pols set
Structure and function of the fourth subunit (Dpb4p) of DNA polymerase epsilon in Saccharomyces cerevisiae. Tomoko Ohya, Satoko Maki, Yasuo Kawasaki, Akio Sugino Nucleic acids research 2000 pols set
Efficient and accurate replication in the presence of 7,8-dihydro-8-oxoguanine by DNA polymerase eta. Lajos Haracska, Sung-Lim Yu, Robert E Johnson, Louise Prakash, Satya Prakash Nat Genet 2000 new
Subunit-specific degradation of the UmuD/D' heterodimer by the ClpXP protease: the role of trans recognition in UmuD' stability. Martín Gonzalez, F Rasulova, M R Maurizi, Roger Woodgate The EMBO journal 2000 new
Studies on a novel DNA polymerase inhibitor group, synthetic sulfoquinovosylacylglycerols: inhibitory action on cell proliferation. Keisuke Ohta, Shinya Hanashima, Yoshiyuki Mizushina, Takayuki Yamazaki, Mineo Saneyoshi, Fumio Sugawara, Kengo Sakaguchi Mutation research 2000 pols set
Polyanionic (i.e., polysulfonate) dendrimers can inhibit the replication of human immunodeficiency virus by interfering with both virus adsorption and later steps (reverse transcriptase/integrase) in the virus replicative cycle. Myriam Witvrouw, Valery Fikkert, Wim Pluymers, B Matthews, K Mardel, Dominique Schols, J Raff, Zeger Debyser, Erik De Clercq, G Holan, Christophe Pannecouque Molecular pharmacology 2000 pols set
Reduced susceptibility of human immunodeficiency virus type 1 (HIV-1) from patients with primary HIV infection to nonnucleoside reverse transcriptase inhibitors is associated with variation at novel amino acid sites. A J Brown, H M Precious, Jeannette M Whitcomb, J K Wong, M Quigg, Wei Huang, E S Daar, R T D'Aquila, P H Keiser, E Connick, Nicholas S Hellmann, Christos J Petropoulos, Douglas D Richman, S J Little Journal of virology 2000 pols set
Novel anti-inflammatory compounds from Myrsine seguinii, terpeno-benzoic acids, are inhibitors of mammalian DNA polymerases. Yoshiyuki Mizushina, S Miyazaki, Keisuke Ohta, Mitsuru Hirota, Kengo Sakaguchi Biochimica et biophysica acta 2000 new
The biochemical mode of inhibition of DNA polymerase beta by alpha-rubromycin. Yoshiyuki Mizushina, T Ueno, M Oda, Tsuyoshi Yamaguchi, Mineo Saneyoshi, Kengo Sakaguchi Biochimica et biophysica acta 2000 new
Fidelity analysis of HIV-1 reverse transcriptase mutants with an altered amino-acid sequence at residues Leu74, Glu89, Tyr115, Tyr183 and Met184. H Jonckheere, Erik De Clercq, J Anné European journal of biochemistry / FEBS 2000 pols set
The HIV-1 reverse transcription (RT) process as target for RT inhibitors. H Jonckheere, J Anné, Erik De Clercq Medicinal research reviews 2000 pols set
Resistance of herpes simplex virus type 1 against different phosphonylmethoxyalkyl derivatives of purines and pyrimidines due to specific mutations in the viral DNA polymerase gene. Graciella Andrei, Robert Snoeck, Erik De Clercq, Robert Esnouf, Pierre Fiten, Ghislain Opdenakker The Journal of general virology 2000 new
Inhibition of adenovirus DNA polymerase by modified nucleoside triphosphate analogs correlate with their antiviral effects on cellular level. R Mentel, S Kurek, U Wegner, M Janta-Lipinski, L Gürtler, E Matthes Med Microbiol Immunol 2000 new
Genomic structure, chromosomal localization and identification of mutations in the xeroderma pigmentosum variant (XPV) gene. M Yuasa, Chikahide Masutani, Toshihiko Eki, Fumio Hanaoka Oncogene 2000 new
Coping with replication 'train wrecks' in Escherichia coli using Pol V, Pol II and RecA proteins. Myron F Goodman Trends in biochemical sciences 2000 new
Molecular mechanism and energetics of clamp assembly in Escherichia coli. The role of ATP hydrolysis when gamma complex loads beta on DNA. Jeffrey G Bertram, Linda B Bloom, Manju M Hingorani, J M Beechem, Mike E O'Donnell, Myron F Goodman The Journal of biological chemistry 2000 pols set
Identification of a fourth subunit of mammalian DNA polymerase delta. Lingfeng Liu, J Mo, Esther M Rodriguez-Belmonte, Marietta Y W T Lee The Journal of biological chemistry 2000 pols set
Fidelity of eucaryotic DNA polymerase delta holoenzyme from Schizosaccharomyces pombe. Xinbin Chen, S Zuo, Zvi Kelman, Mike E O'Donnell, Jerard Hurwitz, Myron F Goodman The Journal of biological chemistry 2000 new
Tracking sliding clamp opening and closing during bacteriophage T4 DNA polymerase holoenzyme assembly. S C Alley, E Abel-Santos, Stephen J Benkovic Biochemistry 2000 pols set
Mutational analysis of trp-229 of human immunodeficiency virus type 1 reverse transcriptase (RT) identifies this amino acid residue as a prime target for the rational design of new non-nucleoside RT inhibitors. H Pelemans, Robert Esnouf, Erik De Clercq, Jan Balzarini Molecular pharmacology 2000 pols set
Melanin binds reversibly to thermostable DNA polymerase and inhibits its activity. L Eckhart, J Bach, J Ban, E Tschachler Biochem Biophys Res Commun 2000 new
Structure of lithocholic acid binding to the N-terminal 8-kDa domain of DNA polymerase beta. Yoshiyuki Mizushina, Tadayasu Ohkubo, Fumio Sugawara, Kengo Sakaguchi Biochemistry 2000 new
A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1. Christos J Petropoulos, N T Parkin, K L Limoli, Y S Lie, Terri Wrin, Wei Huang, H Tian, D Smith, G A Winslow, D J Capon, Jeannette M Whitcomb Antimicrob Agents Chemother 2000 new
Characterization of the unique C terminus of the Escherichia coli tau DnaX protein. Monomeric C-tau binds alpha AND DnaB and can partially replace tau in reconstituted replication forks. H Garry Dallmann, Sangbumn Kim, Arthur E Pritchard, K J Marians, Charles S McHenry The Journal of biological chemistry 2000 new
A carboxylate triad is essential for the polymerase activity of Escherichia coli DNA polymerase I (Klenow fragment). Presence of two functional triads at the catalytic center. Rajiv Gangurde, Neerja Kaushik, Kamalendra Singh, Mukund J Modak The Journal of biological chemistry 2000 pols set
Cross-utilization of the beta sliding clamp by replicative polymerases of evolutionary divergent organisms. N Klemperer, D Zhang, Maija Skangalis, Mike E O'Donnell The Journal of biological chemistry 2000 topics set
The catalytic subunit of herpes simplex virus type 1 DNA polymerase contains a nuclear localization signal in the UL42-binding region. Arianna Loregian, E Piaia, Enrico Cancellotti, E Papini, Howard S Marsden, Giorgio Palù Virology 2000 new
FEN1 stimulation of DNA polymerase beta mediates an excision step in mammalian long patch base excision repair. Rajendra Prasad, Grigory L Dianov, Vilhelm A Bohr, Samuel H Wilson The Journal of biological chemistry 2000 new
Cloning and characterization of the 5'-upstream sequence governing the cell cycle-dependent transcription of mouse DNA polymerase alpha 68 kDa subunit gene. N S Nishikawa, M Izumi, H Uchida, Masayuki Yokoi, Hiroshi Miyazawa, Fumio Hanaoka Nucleic acids research 2000 new
Emergence of zidovudine resistance in HIV-infected patients receiving stavudine. C de Mendoza, V Soriano, C Briones, O Gallego, P Barreiro, A Alvarez, J González-Lahoz J Acquir Immune Defic Syndr 2000 topics set
Pentacyclic triterpenoids from Freziera sp. that inhibit DNA polymerase beta. Jing-Zhen Deng, Shelley R Starck, Sidney M Hecht Bioorg Med Chem 2000 new
Cloning, expression, and characterization of DNA polymerase I from the hyperthermophilic archaea Thermococcus fumicolans. M A Cambon-Bonavita, Philippe Schmitt, Montserrat Zieger, J M Flaman, F Lesongeur, G Raguénès, D Bindel, N Frisch, Z Lakkis, D Dupret, G Barbier, J Quérellou Extremophiles 2000 new
[Isolation and identification of HN-98 strain of spotted fever group rickettsiae]. B Chang, Jinchun Zhang, Xiaoping Tian, D Bi, J Cai, Yong Zhang, Z Lu Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 2000 new
Kinetic analysis of Sp1-mediated transcriptional activation of the human DNA polymerase beta promoter. Satya Narayan, Samuel H Wilson Oncogene 2000 pols set
Specificity of DNA lesion bypass by the yeast DNA polymerase eta. Fenghua Yuan, Yongqing Zhang, D K Rajpal, Xiaoming Wu, Dongyu Guo, Michael Wang, John-Stephen Taylor, Zhengqiang Wang The Journal of biological chemistry 2000 new
Current lead natural products for the chemotherapy of human immunodeficiency virus (HIV) infection. Erik De Clercq Medicinal research reviews 2000 pols set
A strategy for rapid cDNA cloning from double-stranded RNA templates isolated from plants infected with RNA viruses by using Taq DNA polymerase. Y P Zhang, A Rowhani Journal of virological methods 2000 pols set
Prevalence and characteristics of multinucleoside-resistant human immunodeficiency virus type 1 among European patients receiving combinations of nucleoside analogues. K Van Vaerenbergh, Kristel Van Laethem, J Albert, Charles A B Boucher, B Clotet, M Floridia, J Gerstoft, B Hejdeman, C Nielsen, Christophe Pannecouque, L Perrin, M F Pirillo, L Ruiz, J C Schmit, F Schneider, A Schoolmeester, Rob Schuurman, H J Stellbrink, L Stuyver, J Van Lunzen, Barbara Van Remoortel, Eric Van Wijngaerden, S Vella, Myriam Witvrouw, Sabine Yerly, Erik De Clercq, J Destmyer, Anne-Mieke Vandamme Antimicrobial agents and chemotherapy 2000 pols set
Sequences within Pr160gag-pol affecting the selective packaging of primer tRNA(Lys3) into HIV-1. A Khorchid, H Javanbakht, S Wise, R Halwani, Michael A. Parniak, Mark A. Wainberg, Lawrence Kleiman Journal of molecular biology 2000 pols set
The complex of DNA gyrase and quinolone drugs on DNA forms a barrier to the T7 DNA polymerase replication complex. L M Wentzell, A Maxwell Journal of molecular biology 2000 pols set
Mechanism by which phosphonoformic acid resistance mutations restore 3'-azido-3'-deoxythymidine (AZT) sensitivity to AZT-resistant HIV-1 reverse transcriptase. Dominique Arion, Nicolas Sluis-Cremer, Michael A. Parniak The Journal of biological chemistry 2000 topics set
Normal immune function in young and old DNA polymerase-beta deficient mice. M A Pahlavani, D M Vargas, ZhongMao Guo, Arlan Richardson Immunol Lett 2000 new
The PCNA from Thermococcus fumicolans functionally interacts with DNA polymerase delta. Ghislaine Henneke, Jean-Paul Raffin, Elena Ferrari, Z O Jónsson, Jacques Dietrich, Ulrich Hübscher Biochem Biophys Res Commun 2000 pols set
Molecular architecture of the mutagenic active site of human immunodeficiency virus type 1 reverse transcriptase: roles of the beta 8-alpha E loop in fidelity, processivity, and substrate interactions. K K Weiss, S J Isaacs, N H Tran, Elinor T Adman, Baek Kim Biochemistry 2000 pols set
Compartmentalization of phage phi29 DNA replication: interaction between the primer terminal protein and the membrane-associated protein p1. Alicia Bravo, B Illana, Margarita Salas The EMBO journal 2000 pols set
Overexpression of the catalytic subunit of DNA polymerase gamma results in depletion of mitochondrial DNA in Drosophila melanogaster. E Lefai, Manuel Calleja, I Ruiz de Mena, Anthony T Lagina, Laurie S Kaguni, Rafael Garesse Mol Gen Genet 2000 new
Characterization of the human DNA polymerase delta catalytic subunit expressed by a recombinant baculovirus. S Suzuki, Motoshi Suzuki, Shonen Yoshida Nagoya J Med Sci 2000 pols set
A new 7,8-euphadien-type triterpenoid from Brackenridgea nitida and Bleasdalea bleasdalei that inhibits DNA polymerase beta. Jing-Zhen Deng, Shelley R Starck, Di-An Sun, M Sabat, Sidney M Hecht J Nat Prod 2000 new
Roles of DNA polymerase zeta and Rev1 protein in eukaryotic mutagenesis and translesion replication. Christopher W Lawrence, Peter E M Gibbs, R S Murante, X D Wang, Zhongjie Li, Terrence P McManus, William Glenn McGregor, John R Nelson, David C Hinkle, Veronica M Maher Cold Spring Harbor symposia on quantitative biology 2000 new
Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis. Ayelet Maor-Shoshani, N B Reuven, Guy Tomer, Zvi Livneh Proceedings of the National Academy of Sciences of the United States of America 2000 partial results
In vitro selection of mutations in the human immunodeficiency virus type 1 reverse transcriptase that decrease susceptibility to (-)-beta-D-dioxolane-guanosine and suppress resistance to 3'-azido-3'-deoxythymidine. Holly Z Bazmi, J L Hammond, S C Cavalcanti, Chung K Chu, Raymond F Schinazi, John W Mellors Antimicrobial agents and chemotherapy 2000 pols set
8-oxodGTP incorporation by DNA polymerase beta is modified by active-site residue Asn279. Holly Miller, Rajendra Prasad, Samuel H Wilson, Francis Johnson, Arthur P Grollman Biochemistry 2000 new
Phage phi 29 DNA polymerase residues involved in the proper stabilisation of the primer-terminus at the 3'-5' exonuclease active site. Miguel de Vega, José María Lázaro, Margarita Salas Journal of molecular biology 2000 pols set
Identification of conserved residues contributing to the activities of adenovirus DNA polymerase. Huanting Liu, James H Naismith, R T Hay J Virol 2000 new
Molecular cloning and expression during development of the Drosophila gene for the catalytic subunit of DNA polymerase epsilon. Masahiko Oshige, Hiromi Yoshida, Fumiko Hirose, K I Takata, Y Inoue, N Aoyagi, Masamitsu Yamaguchi, Osamu Koiwai, Akio Matsukage, Kengo Sakaguchi Gene 2000 new
Characterization of a novel DNA primase from the Salmonella typhimurium bacteriophage SP6. T Y Tseng, David N Frick, Charles C Richardson Biochemistry 2000 pols set
The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase. Hong Qiang Gao, Paul L Boyer, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes Journal of molecular biology 2000 topics set
Purification and characterization of a new DNA polymerase modulator from the hyperthermophilic archaeon Thermococcus fumicolans. Jean-Paul Raffin, Ghislaine Henneke, Jacques Dietrich Comp Biochem Physiol B Biochem Mol Biol 2000 new
Anti-(herpes simplex virus) activity of 4'-thio-2'-deoxyuridines: a biochemical investigation for viral and cellular target enzymes. A Verri, Federico Focher, R J Duncombe, I Basnak, R T Walker, P L Coe, Erik De Clercq, Graciella Andrei, Robert Snoeck, Jan Balzarini, Silvio Spadari The Biochemical journal 2000 new
Loss of base excision repair in aging rat neurons and its restoration by DNA polymerase beta. Kalluri Subba Rao, V V Annapurna, N S Raji, T Harikrishna Brain Res Mol Brain Res 2000 new
Improving dideoxynucleotide-triphosphate utilisation by the hyper-thermophilic DNA polymerase from the archaeon Pyrococcus furiosus. S J Evans, M J Fogg, A Mamone, M Davis, L H Pearl, Bernard A Connolly Nucleic acids research 2000 topics set
A DNA polymerase epsilon mutant that specifically causes +1 frameshift mutations within homonucleotide runs in yeast. Jake M Kirchner, H Tran, Michael A Resnick Genetics 2000 new
Affinity labeling of RNA-polymerase II in the transcriptionally active complex by a phosphorylating analog of the initiation substrate. L K Savinkova, A A Sokolenko, V A Rau, T V Arshinova, Y V Gerasimova, N V Kudryashova, T S Godovikova Biochemistry (Mosc) 2000 topics set
The terminal protein of a linear mitochondrial plasmid is encoded in the N-terminus of the DNA polymerase gene in white-rot fungus Pleurotus ostreatus. E K Kim, J H Jeong, H S Youn, Y B Koo, J H Roe Curr Genet 2000 new
Pyrene nucleotide as a mechanistic probe: evidence for a transient abasic site-like intermediate in the bypass of dipyrimidine photoproducts by T7 DNA polymerase. L Sun, Michael Wang, Eric T Kool, John-Stephen Taylor Biochemistry 2000 pols set
Biochemical mechanisms involved in overcoming HIV resistance to nucleoside inhibitors of reverse transcriptase. Matthias Götte, Mark A. Wainberg Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2000 pols set
A novel assembly mechanism for the DNA polymerase III holoenzyme DnaX complex: association of deltadelta' with DnaX(4) forms DnaX(3)deltadelta'. Arthur E Pritchard, H Garry Dallmann, Bradley P Glover, Charles S McHenry The EMBO journal 2000 pols set
Biological response to ionizing radiation in mouse embryo fibroblasts with a targeted disruption of the DNA polymerase beta gene. M Miura, H Watanabe, K Okochi, T Sasaki, H Shibuya Radiat Res 2000 new
DNA polymerase of the T4-related bacteriophages. Jim D Karam, William H Konigsberg Prog Nucleic Acid Res Mol Biol 2000 new
Disruption of the developmentally regulated Rev3l gene causes embryonic lethality. John P Wittschieben, M K Shivji, E Lalani, M A Jacobs, Federica Marini, Patricia J Gearhart, I Rosewell, G Stamp, Richard D Wood Current biology : CB 2000 topics set
p12(DOC-1), a growth suppressor, associates with DNA polymerase alpha/primase. K Matsuo, S Shintani, T Tsuji, E Nagata, M Lerman, J McBride, Y Nakahara, H Ohyama, R Todd, D T Wong FASEB J 2000 new
Translesion replication by DNA polymerase delta depends on processivity accessory proteins and differs in specificity from DNA polymerase beta. S S Daube, Guy Tomer, Zvi Livneh Biochemistry 2000 new
Structure-activity relationships of acyloxyamidine cytomegalovirus DNA polymerase inhibitors. J A Tucker, T L Clayton, C G Chidester, M W Schulz, L E Harrington, S J Conrad, Y Yagi, Nancee L Oien, D Yurek, M S Kuo Bioorg Med Chem 2000 new
A unique organization of the protein subunits of the DNA polymerase clamp loader in the archaeon Methanobacterium thermoautotrophicum deltaH. Zvi Kelman, Jerard Hurwitz The Journal of biological chemistry 2000 new
2-Hydroxy-dATP is incorporated opposite G by Escherichia coli DNA polymerase III resulting in high mutagenicity. Hiroyuki Kamiya, Hironori Kasai Nucleic acids research 2000 pols set
Single-molecule studies of the effect of template tension on T7 DNA polymerase activity. G J Wuite, Steven B Smith, M Young, D Keller, Carlos Bustamante Nature 2000 partial results
Inteins of Thermococcus fumicolans DNA polymerase are endonucleases with distinct enzymatic behaviors. I Saves, V Ozanne, Jacques Dietrich, J M Masson The Journal of biological chemistry 2000 pols set
Increased rates of genomic deletions generated by mutations in the yeast gene encoding DNA polymerase delta or by decreases in the cellular levels of DNA polymerase delta. Robert J Kokoska, L Stefanovic, J DeMai, Thomas D Petes Molecular and cellular biology 2000 new
Comparison of human cytomegalovirus DNA polymerase activity for ganciclovir-resistant and -sensitive clinical strains. M Kariya, S Mori, Y Eizuru Antiviral Res 2000 pols set
[A photoreactive analogue of 2'3'-dideoxyuridine 5'-triphosphate: preparation and use for photoaffinity modification of human replication protein A]. Dmitry M Kolpashchikov, L A Aleksandrova, N F Zakirova, Svetlana N Khodyreva, Olga I Lavrik Bioorganicheskaia khimiia 2000 new
Epolactaene, a novel neuritogenic compound in human neuroblastoma cells, selectively inhibits the activities of mammalian DNA polymerases and human DNA topoisomerase II. Yoshiyuki Mizushina, Susumu Kobayashi, Kouji Kuramochi, Seigo Nagata, Fumio Sugawara, Kengo Sakaguchi Biochemical and biophysical research communications 2000 new
Crystal structure of a pol alpha family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. 9 degrees N-7. A C Rodriguez, H W Park, C Mao, Lorena S Beese Journal of molecular biology 2000 partial results
Valine of the YVDD motif of moloney murine leukemia virus reverse transcriptase: role in the fidelity of DNA synthesis. Neerja Kaushik, K Chowdhury, V N Pandey, Mukund J Modak Biochemistry 2000 pols set
Selection and characterization of human immunodeficiency virus type 1 variants resistant to the (+) and (-) enantiomers of 2'-deoxy-3'-oxa-4'-thio-5-fluorocytidine. N Richard, H Salomon, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg Antimicrobial agents and chemotherapy 2000 pols set
Role of Q190 of MuLV RT in ddNTP resistance and fidelity of DNA synthesis: a molecular model of interactions with substrates. Kamalendra Singh, Neerja Kaushik, J Jin, M Madhusudanan, Mukund J Modak Protein engineering 2000 pols set
Activity of DNA polymerase alpha in aging human fibroblasts. Vinod K Srivastava, S Miller, M Schroeder, E Crouch, D Busbee Biogerontology 2000 new
Ara-C differentially affects multiprotein forms of human cell DNA polymerase. P W Wills, Robert Hickey, Linda Malkas Cancer Chemother Pharmacol 2000 new
Coordination between the polymerase and 5'-nuclease components of DNA polymerase I of Escherichia coli. Y Xu, Nigel D F Grindley, Catherine M Joyce The Journal of biological chemistry 2000 complete Joshua Mazzola
Preliminary X-ray crystallographic and NMR studies on the exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III. Samir M Hamdan, Susan E Brown, Phillip R Thompson, Ji Yeon Yang, Paul D Carr, David L Ollis, Gottfried Otting, Nicholas E Dixon J Struct Biol 2000 pols set
The many faces of DNA polymerases: strategies for mutagenesis and for mutational avoidance. Errol C Friedberg, William J Feaver, Valerie L Gerlach Proceedings of the National Academy of Sciences of the United States of America 2000 topics set
Replication of a site-specific trans-8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B(1) adduct by the exonuclease deficient klenow fragment of DNA polymerase I. D S Johnston, Michael P Stone Chemical research in toxicology 2000 pols set
DNA polymerase beta and mammalian base excision repair. Samuel H Wilson, Robert W Sobol, William A Beard, Julie K Horton, Rajendra Prasad, Brian J Vande Berg Cold Spring Harbor symposia on quantitative biology 2000 new
DNA polymerase active site is highly mutable: evolutionary consequences. P H Patel, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 2000 topics set
DNA polymerase mu (Pol mu), homologous to TdT, could act as a DNA mutator in eukaryotic cells. Orlando Domínguez, José F Ruiz, Teresa Laín de Lera, Miguel García-Díaz, Manuel A González, Tomas Kirchhoff, Carlos Martínez-A, Antonio Bernad, Luis Blanco The EMBO journal 2000 partial results
Differential removal of thymidine nucleotide analogues from blocked DNA chains by human immunodeficiency virus reverse transcriptase in the presence of physiological concentrations of 2'-deoxynucleoside triphosphates. Peter R Meyer, Suzanne E Matsuura, Raymond F Schinazi, Antero G So, Walter A Scott Antimicrob Agents Chemother 2000 topics set
Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses. Jingshan Ren, J Diprose, J Warren, R M Esnouf, Louise E Bird, Shinji Ikemizu, M Slater, John Milton, Jan Balzarini, David I Stuart, David K Stammers The Journal of biological chemistry 2000 pols set
Evaluating Clinical Isolates for Their Phenotypic and Genotypic Resistance Against Anti-HIV Drugs. A-M Vandamme, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Kristel Van Laethem, J C Schmit, J Desmyter, Erik De Clercq Methods in molecular medicine 2000 pols set
The J-helix of Escherichia coli DNA polymerase I (Klenow fragment) regulates polymerase and 3'- 5'-exonuclease functions. Steven Tuske, Kamalendra Singh, Neerja Kaushik, Mukund J Modak The Journal of biological chemistry 2000 pols set
Analysis of the Okazaki fragment distributions along single long DNAs replicated by the bacteriophage T4 proteins. Paul D Chastain, Alexander M Makhov, Nancy G Nossal, Jack D Griffith Molecular cell 2000 complete
Hydrophobic interactions in the hinge domain of DNA polymerase beta are important but not sufficient for maintaining fidelity of DNA synthesis. Patricia L Opresko, R Shiman, Kristin A Eckert Biochemistry 2000 pols set
Mutational analysis of Lys65 of HIV-1 reverse transcriptase. Nicolas Sluis-Cremer, Dominique Arion, Neerja Kaushik, H Lim, Michael A. Parniak Biochem J 2000 pols set
Interactions of conformationally biased north and south 2'-fluoro-2', 3'-dideoxynucleoside 5'-triphosphates with the active site of HIV-1 reverse transcriptase. L Mu, Stefan G Sarafianos, Marc C Nicklaus, P Russ, Maqbool A Siddiqui, H Ford, Hiroyuki Mitsuya, R Le, Eiichi N Kodama, Chris Meier, T Knispel, L Anderson, Joseph J Barchi, Victor E Marquez Biochemistry 2000 topics set
Fidelity of human DNA polymerase eta. Robert E Johnson, M Todd Washington, Satya Prakash, Louise Prakash The Journal of biological chemistry 2000 pols set
The effect of mutations in the HIV-1 nucleocapsid protein on strand transfer in cell-free reverse transcription reactions. M Hsu, Liwei Rong, H de Rocquigny, Bernard P Roques, Mark A. Wainberg Nucleic acids research 2000 new
The M184V mutation in the reverse transcriptase of human immunodeficiency virus type 1 impairs rescue of chain-terminated DNA synthesis. Matthias Götte, Dominique Arion, Michael A. Parniak, Mark A. Wainberg J Virol 2000 topics set
Leading and lagging strand DNA synthesis in vitro by a reconstituted herpes simplex virus type 1 replisome. M Falkenberg, I. Robert Lehman, P Elias Proceedings of the National Academy of Sciences of the United States of America 2000 new
Evaluation of Compounds Against Recombinant HIV Reverse Transcriptase. Jan Balzarini Methods in molecular medicine 2000 pols set
The DnaX-binding subunits delta' and psi are bound to gamma and not tau in the DNA polymerase III holoenzyme. Bradley P Glover, Charles S McHenry The Journal of biological chemistry 2000 new
Nucleotide excision repair of DNA with recombinant human proteins: definition of the minimal set of factors, active forms of TFIIH, and modulation by CAK. S J Araújo, F Tirode, F Coin, Helmut Pospiech, Juhani E Syväoja, M Stucki, Ulrich Hübscher, J M Egly, Richard D Wood Genes & development 2000 pols set
[Rapid detection of drug resistant HIV -1 to reverse transcriptase and protease inhibitors in HIV-infected patients receiving highly active antiretroviral therapies]. Ming Yu, W Kabat, Jian Wang Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 2000 pols set
Dinucleotide repeat expansion catalyzed by bacteriophage T4 DNA polymerase in vitro. E F da Silva, Linda J Reha-Krantz The Journal of biological chemistry 2000 complete
Cyclin A activates the DNA polymerase delta -dependent elongation machinery in vitro: A parvovirus DNA replication model. T Bashir, R Horlein, J Rommelaere, K Willwand Proceedings of the National Academy of Sciences of the United States of America 2000 new
Inhibitors of HIV-1 reverse transcriptase. Michael A. Parniak, Nicolas Sluis-Cremer Advances in pharmacology (San Diego, Calif.) 2000 pols set
Characterization of the 5'-flanking region of the gene encoding the 50 kDa subunit of human DNA polymerase delta. A Perez, A Leon, Marietta Y W T Lee Biochimica et biophysica acta 2000 pols set
Role of yeast and human DNA polymerase eta in error-free replication of damaged DNA. Satya Prakash, Robert E Johnson, M Todd Washington, Lajos Haracska, Christine M Kondratick, Louise Prakash Cold Spring Harbor symposia on quantitative biology 2000 pols set
Human immunodeficiency virus type-1 reverse transcription can be inhibited in vitro by oligonucleotides that target both natural and synthetic tRNA primers. Xin Wei, Matthias Götte, Mark A. Wainberg Nucleic acids research 2000 new
Replication by a single DNA polymerase of a stretched single-stranded DNA. B Maier, D Bensimon, V Croquette Proceedings of the National Academy of Sciences of the United States of America 2000 new
Nucleotide-sequence-specific and non-specific interactions of T4 DNA polymerase with its own mRNA. Andrey R Pavlov, Jim D Karam Nucleic acids research 2000 complete
The DNA replication machine of a gram-positive organism. Irina Bruck, Mike E O'Donnell The Journal of biological chemistry 2000 pols set
PCR performance of the B-type DNA polymerase from the thermophilic euryarchaeon Thermococcus aggregans improved by mutations in the Y-GG/A motif. K Böhlke, Francesca M Pisani, C E Vorgias, B Frey, H Sobek, Mosè Rossi, G Antranikian Nucleic acids research 2000 new
Preferential interaction of loach DNA polymerase delta with DNA duplexes containing single-stranded gaps. N P Sharova, E B Abramova, S B Dmitrieva, D D Dimitrova, V S Mikhailov FEBS letters 2000 new
Differential effects of N-acetyl-2-aminofluorene and N-2-aminofluorene adducts on the conformational change in the structure of DNA polymerase I (Klenow fragment). Leonid Dzantiev, Louis J Romano Biochemistry 2000 pols set
Selective interaction of the human immunodeficiency virus type 1 reverse transcriptase nonnucleoside inhibitor efavirenz and its thio-substituted analog with different enzyme-substrate complexes. Giovanni Maga, D Ubiali, R Salvetti, M Pregnolato, Silvio Spadari Antimicrobial agents and chemotherapy 2000 new
Characterization of human herpesvirus 8 ORF59 protein (PF-8) and mapping of the processivity and viral DNA polymerase-interacting domains. S R Chan, B Chandran J Virol 2000 new
Presence of 2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5"-(4"-amino-1",2"-oxath iole-2",2"-dioxide) (TSAO)-resistant virus strains in TSAO-inexperienced HIV patients. Kristel Van Laethem, J C Schmit, H Pelemans, Jan Balzarini, Myriam Witvrouw, María-Jesús Pérez-Pérez, María-José Camarasa, R M Esnouf, Stefano Aquaro, A Cenci, CF Perno, P Hermans, S Sprecher, L Ruiz, B Clotet, Eric Van Wijngaerden, M Van Ranst, J Desmyter, Erik De Clercq, A-M Vandamme AIDS research and human retroviruses 2000 pols set
Differential expression of DNA polymerase epsilon in resting and activated B lymphocytes is consistent with an in vivo role in replication and not repair. D B Winter, Q H Phung, Richard D Wood, Patricia J Gearhart Mol Immunol 2000 new
Importance of terminal base pair hydrogen-bonding in 3'-end proofreading by the Klenow fragment of DNA polymerase I. J C Morales, Eric T Kool Biochemistry 2000 pols set
Lethal mutagenesis of HIV by mutagenic ribonucleoside analogs. Lawrence A Loeb, J I Mullins AIDS research and human retroviruses 2000 pols set
Dynamics of beta and proliferating cell nuclear antigen sliding clamps in traversing DNA secondary structure. N Yao, Jerard Hurwitz, Mike E O'Donnell The Journal of biological chemistry 2000 new
Structural design of a eukaryotic DNA repair polymerase: DNA polymerase beta. William A Beard, Samuel H Wilson Mutation research 2000 new
Low fidelity DNA synthesis by human DNA polymerase-eta. Toshiro Matsuda, Katarzyna Bebenek, Chikahide Masutani, Fumio Hanaoka, Thomas A Kunkel Nature 2000 partial results
An aspartic acid residue in TPR-1, a specific region of protein-priming DNA polymerases, is required for the functional interaction with primer terminal protein. Emmanuelle Dufour, Juan Méndez, José María Lázaro, Miguel de Vega, Luis Blanco, Margarita Salas Journal of molecular biology 2000 partial results
MSSP, a protein binding to an origin of replication in the c-myc gene, interacts with a catalytic subunit of DNA polymerase alpha and stimulates its polymerase activity. T Niki, I Galli, H Ariga, S M Iguchi-Ariga FEBS letters 2000 pols set
Resistance to antiretroviral drugs in patients with primary HIV-1 infection. Investigators of the Quebec Primary Infection Study. Bluma G Brenner, Mark A. Wainberg, H Salomon, D Rouleau, A Dascal, Bonnie Spira, Rafick-Pierre Sekaly, Brian Conway, Jean-Pierre Routy International journal of antimicrobial agents 2000 pols set
Role of human telomerase reverse transcriptase and telomeric-repeat binding factor proteins 1 and 2 in human hematopoietic cells. K Yamada, T Yajima, A Yagihashi, D Kobayashi, Y Koyanagi, K Asanuma, Masami Yamada, R Moriai, H Kameshima, N Watanabe Japanese journal of cancer research : Gann 2000 pols set
Translesion replication by DNA polymerase beta is modulated by sequence context and stimulated by fork-like flap structures in DNA. S S Daube, Gali Arad, Zvi Livneh Biochemistry 2000 new
Polymerization of 2'-fluoro- and 2'-O-methyl-dNTPs by human DNA polymerase alpha, polymerase gamma, and primase. Frank C Richardson, Robert D Kuchta, A Mazurkiewicz, Katherine A Richardson Biochem Pharmacol 2000 pols set
Initiation of eukaryotic DNA replication: origin unwinding and sequential chromatin association of Cdc45, RPA, and DNA polymerase alpha. J Walter, J Newport Molecular cell 2000 new
Differentiation of rat pheochromocytoma cells by fomitellic acids, specific DNA polymerase inhibitors. Y Obara, N Nakahata, Yoshiyuki Mizushina, Fumio Sugawara, Kengo Sakaguchi, Y Ohizumi Life Sci 2000 new
Use of an N-terminal fragment from moloney murine leukemia virus reverse transcriptase to facilitate crystallization and analysis of a pseudo-16-mer DNA molecule containing G-A mispairs. Marie L Coté, S J Yohannan, Millie M Georgiadis Acta Crystallogr D Biol Crystallogr 2000 new
The efficiency and fidelity of translesion synthesis past cisplatin and oxaliplatin GpG adducts by human DNA polymerase beta. Alexandra Vaisman, Stephen G Chaney The Journal of biological chemistry 2000 pols set
In vitro expansion of mammalian telomere repeats by DNA polymerase alpha-primase. K Nozawa, Motoshi Suzuki, Masaharu Takemura, Shonen Yoshida Nucleic acids research 2000 new
Resistance profile of the human immunodeficiency virus type 1 reverse transcriptase inhibitor abacavir (1592U89) after monotherapy and combination therapy. CNA2001 Investigative Group. P Richard Harrigan, C Stone, P Griffin, I Nájera, Stuart Bloor, S Kemp, M Tisdale, Brendan A Larder J Infect Dis 2000 topics set
Role of a dipeptide insertion between codons 69 and 70 of HIV-1 reverse transcriptase in the mechanism of AZT resistance. Antonio Mas, M Parera, C Briones, V Soriano, Miguel Angel Martínez, Esteban Domingo, L Menéndez-Arias The EMBO journal 2000 topics set
DNA polymerase beta is required for efficient DNA strand break repair induced by methyl methanesulfonate but not by hydrogen peroxide. Paola Fortini, Barbara Pascucci, F Belisario, Eugenia Dogliotti Nucleic acids research 2000 new
Crystal structure of the DNA polymerase processivity factor of T4 bacteriophage. I Moarefi, David Jeruzalmi, J Turner, Mike E O'Donnell, John Kuriyan Journal of molecular biology 2000 topics set
Functional interdependence of DNA polymerizing and 3'-->5' exonucleolytic activities in Pyrococcus furiosus DNA polymerase I. Kayoko Komori, Yoshizumi Ishino Protein Eng 2000 pols set
DNA replication fidelity. Thomas A Kunkel, Katarzyna Bebenek Annual review of biochemistry 2000 topics set
Escherichia coli DNA polymerase III tau- and gamma-subunit conserved residues required for activity in vivo and in vitro. J R Walker, C Hervas, J D Ross, A Blinkova, M J Walbridge, E J Pumarega, M O Park, H R Neely J Bacteriol 2000 pols set
Molecular cloning of a gene (poIA) coding for an unusual DNA polymerase I from Treponema pallidum. B Rodes, Huanting Liu, S Johnson, R George, B Steiner J Med Microbiol 2000 new
Cid1, a fission yeast protein required for S-M checkpoint control when DNA polymerase delta or epsilon is inactivated. S W Wang, T Toda, R MacCallum, A L Harris, C Norbury Molecular and cellular biology 2000 topics set
Efficient translesion replication past oxaliplatin and cisplatin GpG adducts by human DNA polymerase eta. Alexandra Vaisman, Chikahide Masutani, Fumio Hanaoka, Stephen G Chaney Biochemistry 2000 pols set
Error-free and error-prone lesion bypass by human DNA polymerase kappa in vitro. Yongqing Zhang, Fenghua Yuan, Xiaoming Wu, Michael Wang, Olga Rechkoblit, John-Stephen Taylor, Nicholas E Geacintov, Zhengqiang Wang Nucleic acids research 2000 pols set
Partial purification and characterization of mitochondrial DNA polymerase from Plasmodium falciparum. Porntip Chavalitshewinkoon-Petmitr, S Chawprom, Lieve Naesens, Jan Balzarini, P Wilairat Parasitol Int 2000 new
Proteolysis of the human DNA polymerase epsilon catalytic subunit by caspase-3 and calpain specifically during apoptosis. W Liu, Stuart Linn Nucleic acids research 2000 pols set
Complementation of defective translesion synthesis and UV light sensitivity in xeroderma pigmentosum variant cells by human and mouse DNA polymerase eta. Ayumi Yamada, Chikahide Masutani, Shigenori Iwai, Fumio Hanaoka Nucleic acids research 2000 new
5'-nicked apurinic/apyrimidinic sites are resistant to beta-elimination by beta-polymerase and are persistent in human cultured cells after oxidative stress. J Nakamura, D K La, James A Swenberg The Journal of biological chemistry 2000 new
Domain specific interaction in the XRCC1-DNA polymerase beta complex. Assen Marintchev, Anthony Robertson, E K Dimitriadis, Rajendra Prasad, Samuel H Wilson, Gregory P Mullen Nucleic acids research 2000 new
Novel agents for the therapy of varicella-zoster virus infections. Robert Snoeck, Graciella Andrei, Erik De Clercq Expert opinion on investigational drugs 2000 new
The highly compact structure of the mitochondrial DNA polymerase genomic region of Drosophila melanogaster: functional and evolutionary implications. E Lefai, Miguel A Fernández-Moreno, Laurie S Kaguni, Rafael Garesse Insect molecular biology 2000 new
Synthesis and anti-HIV activity of cosalane analogues incorporating nitrogen in the linker chain. A Casimiro-Garcia, Erik De Clercq, Christophe Pannecouque, Myriam Witvrouw, T L Stup, J A Turpin, Robert W Buckheit, Mark Cushman Bioorganic & medicinal chemistry 2000 pols set
Selection of resistance-conferring mutations in HIV-1 by the nucleoside reverse transcriptase inhibitors (+/-)dOTC and (+/-)dOTFC. N Richard, H Salomon, Maureen Oliveira, R Rando, T Mansour, Z Gu, Mark A. Wainberg Antiviral chemistry & chemotherapy 2000 pols set
Cloning and characterization of a family B DNA polymerase from the hyperthermophilic crenarchaeon Pyrobaculum islandicum. M Kähler, G Antranikian J Bacteriol 2000 new
Thermus aquaticus DNA polymerase I mutants with altered fidelity. Interacting mutations in the O-helix. Motoshi Suzuki, Shonen Yoshida, Elinor T Adman, A Blank, Lawrence A Loeb The Journal of biological chemistry 2000 pols set
The beta clamp targets DNA polymerase IV to DNA and strongly increases its processivity. Jérôme E Wagner, Shingo Fujii, Petr Grúz, Takehiko Nohmi, Robert P P Fuchs EMBO reports 2000 complete Jérôme E Wagner*
Alteration of ultraviolet-induced mutagenesis in yeast through molecular modulation of the REV3 and REV7 gene expression. D K Rajpal, Xiaoming Wu, Zhengqiang Wang Mutation research 2000 new
The function of DNA polymerase alpha at telomeric G tails is important for telomere homeostasis. A Adams Martin, I Dionne, R J Wellinger, C Holm Molecular and cellular biology 2000 new
DNA polymerase switching: II. Replication factor C abrogates primer synthesis by DNA polymerase alpha at a critical length. R Mossi, R C Keller, Elena Ferrari, Ulrich Hübscher Journal of molecular biology 2000 new
In vitro evaluation of the effect of temporary removal of HIV drug pressure. Myriam Witvrouw, Christophe Pannecouque, J Desmyter, Erik De Clercq, Koen Andries Antiviral research 2000 pols set
Inhibition of the replication of the DNA polymerase M550V mutation variant of human hepatitis B virus by adefovir, tenofovir, L-FMAU, DAPD, penciclovir and lobucavir. Chunxiao Ying, Erik De Clercq, W Nicholson, P Furman, Johan Neyts Journal of viral hepatitis 2000 new
Mapping of the 5'-2-deoxyribose-5-phosphate lyase active site in DNA polymerase beta by mass spectrometry. Leesa J Deterding, Rajendra Prasad, Gregory P Mullen, Samuel H Wilson, Kenneth B Tomer The Journal of biological chemistry 2000 new
Identification and characterization of human DNA polymerase beta 2, a DNA polymerase beta -related enzyme. K Nagasawa, K Kitamura, Akira Yasui, Y Nimura, Kyoji Ikeda, Midori Hirai, Akio Matsukage, Makoto Nakanishi The Journal of biological chemistry 2000 pols set
Probing structure-function relationships of the DNA polymerase alpha-associated zinc-finger protein using computational approaches. R Samudrala, Y Xia, M Levitt, N J Cotton, E S Huang, R Davis Pac Symp Biocomput 2000 new
The crystal structure of an unusual processivity factor, herpes simplex virus UL42, bound to the C terminus of its cognate polymerase. H J Zuccola, David J Filman, Donald M Coen, James M Hogle Molecular cell 2000 partial results
Inhibition of the initiation of HIV-1 reverse transcription by 3'-azido-3'-deoxythymidine. Comparison with elongation. Mickael Rigourd, J M Lanchy, Stuart F J Le Grice, Bernard Ehresmann, Chantal Ehresmann, Roland Marquet The Journal of biological chemistry 2000 complete Roland Marquet*
DNA polymerase lambda (Pol lambda), a novel eukaryotic DNA polymerase with a potential role in meiosis. Miguel García-Díaz, Orlando Domínguez, L A López-Fernández, L T de Lera, M L Saníger, José F Ruiz, M Párraga, M J García-Ortiz, Tomas Kirchhoff, J del Mazo, Antonio Bernad, Luis Blanco Journal of molecular biology 2000 topics set
Structural basis for the resilience of efavirenz (DMP-266) to drug resistance mutations in HIV-1 reverse transcriptase. Jingshan Ren, John Milton, Kurt L Weaver, Steven A Short, David I Stuart, David K Stammers Structure (London, England : 1993) 2000 topics set
Essential interaction between the fission yeast DNA polymerase delta subunit Cdc27 and Pcn1 (PCNA) mediated through a C-terminal p21(Cip1)-like PCNA binding motif. N Reynolds, Emma Warbrick, P A Fantes, Stuart A MacNeill The EMBO journal 2000 new
Protein sequences conserved in prokaryotic aminoacyl-tRNA synthetases are important for the activity of the processivity factor of human mitochondrial DNA polymerase. José A Carrodeguas, Daniel F Bogenhagen Nucleic acids research 2000 new
In vitro antimicrobial activities of novel anilinouracils which selectively inhibit DNA polymerase III of gram-positive bacteria. J S Daly, T J Giehl, Neal C Brown, Chengxin Zhi, George E Wright, R T Ellison Antimicrob Agents Chemother 2000 new
Neonatal lethality with abnormal neurogenesis in mice deficient in DNA polymerase beta. Noriyuki Sugo, Yasuaki Aratani, Y Nagashima, Y Kubota, Hideki Koyama The EMBO journal 2000 new
Novel triterpenoids inhibit both DNA polymerase and DNA topoisomerase. Yoshiyuki Mizushina, A Iida, Keisuke Ohta, Fumio Sugawara, Kengo Sakaguchi Biochem J 2000 pols set
Common pathways for ultraviolet skin carcinogenesis in the repair and replication defective groups of xeroderma pigmentosum. James E Cleaver Journal of dermatological science 2000 topics set
Incorporation of 4-thiothymidine into DNA by the Klenow fragment and HIV-1 reverse transcriptase. T V Rao, M T Haber, Jane M Sayer, Donald M Jerina Bioorganic & medicinal chemistry letters 2000 pols set
Naphthalene carboxamides as inhibitors of human cytomegalovirus DNA polymerase. V A Vaillancourt, M M Cudahy, S A Staley, Roger J Brideau, S J Conrad, Mary L Knechtel, Nancee L Oien, Janet L Wieber, Y Yagi, Michael W Wathen Bioorganic & medicinal chemistry letters 2000 pols set
Preparation and enzymatic recognition of guanine lesions induced by nitrogen oxides. Aya Masaoka, Hiroaki Terato, A Honsho, Y Ohyama, Toshinori Suzuki, Masami Yamada, K Makino, Hiroshi Ide Nucleic acids symposium series 2000 new
DNA polymerase I is essential for growth of Methylobacterium dichloromethanicum DM4 with dichloromethane. M F Kayser, M T Stumpp, S Vuilleumier J Bacteriol 2000 new
In vivo functional analysis of the human mitochondrial DNA polymerase POLG expressed in cultured human cells. Johannes N Spelbrink, J M Toivonen, G A Hakkaart, J M Kurkela, H M Cooper, S K Lehtinen, N Lecrenier, J W Back, D Speijer, Françoise Foury, Howard T Jacobs The Journal of biological chemistry 2000 new
Response to antiretroviral therapy in a patient with an uncommon codon 69 insertion in the human immunodeficiency virus type 1 reverse transcriptase. P Bonfanti, I Faggion, S La Seta Catamancio, M Violin, C Balotta, S Rusconi Antimicrob Agents Chemother 2000 topics set
Secondary structure and structure-activity relationships of peptides corresponding to the subunit interface of herpes simplex virus DNA polymerase. K G Bridges, Q Hua, M R Brigham-Burke, J D Martin, P Hensley, C E Dahl, P Digard, M A Weiss, Donald M Coen The Journal of biological chemistry 2000 new
DNA polymerase zeta introduces multiple mutations when bypassing spontaneous DNA damage in Saccharomyces cerevisiae. Brian D Harfe, Sue Jinks-Robertson Molecular cell 2000 new
High-level resistance to 3'-azido-3'-deoxythimidine due to a deletion in the reverse transcriptase gene of human immunodeficiency virus type 1. T Imamichi, T Sinha, H Imamichi, Y M Zhang, J A Metcalf, J Falloon, H C Lane Journal of virology 2000 pols set
Elongation of tandem repetitive DNA by the DNA polymerase of the hyperthermophilic archaeon Thermococcus litoralis at a hairpin-coil transitional state: a model of amplification of a primordial simple DNA sequence. Norio Ogata, T Miura Biochemistry 2000 new
Structural homology between DNA binding sites of DNA polymerase beta and DNA topoisomerase II. Yoshiyuki Mizushina, Fumio Sugawara, A Iida, Kengo Sakaguchi Journal of molecular biology 2000 new
Functional interaction between the Werner Syndrome protein and DNA polymerase delta. Ashwini S Kamath-Loeb, Erik Johansson, Peter M J Burgers, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 2000 new
Ligands selected from combinatorial libraries of protein A for use in affinity capture of apolipoprotein A-1M and taq DNA polymerase. K Nord, E Gunneriusson, M Uhlén, P A Nygren J Biotechnol 2000 pols set
Domain exchange: chimeras of Thermus aquaticus DNA polymerase, Escherichia coli DNA polymerase I and Thermotoga neapolitana DNA polymerase. B Villbrandt, H Sobek, B Frey, D Schomburg Protein engineering 2000 partial results
Structure and activity associated with multiple forms of Schizosaccharomyces pombe DNA polymerase delta. S Zuo, Vladimir Bermudez, G Zhang, Zvi Kelman, Jerard Hurwitz The Journal of biological chemistry 2000 new
Identification of a beta-like DNA polymerase activity in bovine heart mitochondria. S M Nielsen-Preiss, R L Low Arch Biochem Biophys 2000 new
Synthesis of non-natural DNA using DNA polymerase. Yasuhito Ebara, T Sugiyama, K Kaihatsu, Shin-ichi Ueji Nucleic Acids Symp Ser 2000 new
Prevalence of HIV-1 resistant to antiretroviral drugs in 81 individuals newly infected by sexual contact or injecting drug use. Investigators of the Quebec Primary Infection Study. H Salomon, Mark A. Wainberg, Bluma G Brenner, Yudong Quan, D Rouleau, P Coté, R LeBlanc, E Lefebvre, Bonnie Spira, C Tsoukas, Rafick-Pierre Sekaly, Brian Conway, D Mayers, Jean-Pierre Routy AIDS (London, England) 2000 pols set
DNA structure requirements for the Escherichia coli gamma complex clamp loader and DNA polymerase III holoenzyme. N Yao, F P Leu, J Anjelkovic, J Turner, Mike E O'Donnell The Journal of biological chemistry 2000 new
Elongation of repetitive DNA by DNA polymerase from a hyperthermophilic bacterium Thermus thermophilus. N Ogata, H Morino Nucleic acids research 2000 new
DNA polymerase beta: contributions of template-positioning and dNTP triphosphate-binding residues to catalysis and fidelity. V S Kraynov, Alexander K Showalter, Jianhua Liu, Xuejun Zhong, Ming-Daw Tsai Biochemistry 2000 new
Highly selective affinity labeling of DNA-polymerase from Thermus thermophilus B35 by a binary system of photoreactive agents. Nadejda I Rechkunova, Dmitry M Kolpashchikov, Natalia A Lebedeva, Irina O Petruseva, M I Dobrikov, S K Degtyarev, Olga I Lavrik Biochemistry (Mosc) 2000 new
Interaction of the retinoblastoma protein (pRb) with the catalytic subunit of DNA polymerase delta (p125). N A Krucher, A Zygmunt, Nayef Mazloum, S Tamrakar, J W Ludlow, Marietta Y W T Lee Oncogene 2000 new
Sequence requirements for protein-primed initiation and elongation of phage O29 DNA replication. V Gonzalez-Huici, Margarita Salas, José M Hermoso The Journal of biological chemistry 2000 new
The N-terminal region of DNA polymerase delta catalytic subunit is necessary for holoenzyme function. S B Schumacher, M Stucki, Ulrich Hübscher Nucleic acids research 2000 new
Subunit interactions within the Saccharomyces cerevisiae DNA polymerase epsilon (pol epsilon ) complex. Demonstration of a dimeric pol epsilon. Rajiv Dua, Shaune Edwards, Daniel L Levy, Judith L Campbell The Journal of biological chemistry 2000 pols set
DNA polymerase switching: I. Replication factor C displaces DNA polymerase alpha prior to PCNA loading. Giovanni Maga, M Stucki, Silvio Spadari, Ulrich Hübscher Journal of molecular biology 2000 new
The delta subunit of DNA polymerase III holoenzyme serves as a sliding clamp unloader in Escherichia coli. F P Leu, Manju M Hingorani, J Turner, Mike E O'Donnell The Journal of biological chemistry 2000 new
DNA polymerases and Ki-67 nuclear antigen are induced in correlation with the resected mass of rat liver up to 90%. Kengo Sakaguchi, E Takeuchi, Motoshi Suzuki, K Oda, M Nagino, Y Nimura, Shonen Yoshida Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie 2000 new
Progesterone regulates human telomerase reverse transcriptase gene expression via activation of mitogen-activated protein kinase signaling pathway. Zhengqiang Wang, Satoru Kyo, Masahiro Takakura, Masaaki Tanaka, Noriyuki Yatabe, Yoshiko Maida, M Fujiwara, J Hayakawa, Masahide Ohmichi, Koji Koike, Masaki Inoue Cancer research 2000 new
Error-prone bypass of certain DNA lesions by the human DNA polymerase kappa. Eiji Ohashi, Tomoo Ogi, Rika Kusumoto, Shigenori Iwai, Chikahide Masutani, Fumio Hanaoka, Haruo Ohmori Genes Dev 2000 pols set
Specific recognition of parental terminal protein by DNA polymerase for initiation of protein-primed DNA replication. V Gonzalez-Huici, José María Lázaro, Margarita Salas, José M Hermoso The Journal of biological chemistry 2000 pols set
Mice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally. Gloria Esposito, G Texido, U A Betz, H Gu, W Müller, U Klein, Klaus Rajewsky Proceedings of the National Academy of Sciences of the United States of America 2000 new
A model for Escherichia coli DNA polymerase III holoenzyme assembly at primer/template ends. DNA triggers a change in binding specificity of the gamma complex clamp loader. Brandon Ason, Jeffrey G Bertram, Manju M Hingorani, J M Beechem, Mike E O'Donnell, Myron F Goodman, Linda B Bloom The Journal of biological chemistry 2000 pols set
Analysis of proteins encoded in the bipartite genome of a new type of parvo-like virus isolated from silkworm - structural protein with DNA polymerase motif. T Hayakawa, K Kojima, K Nonaka, M Nakagaki, K Sahara, S i Asano, T Iizuka, H Bando Virus Res 2000 new
A unique loop in the DNA-binding crevice of bacteriophage T7 DNA polymerase influences primer utilization. Kajal Chowdhury, Stanley Tabor, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 2000 pols set
[Extension of life-span of normal human fibroblasts by reconstitution of telomerase activity]. Zhengqiang Wang, J Yi, Hong Li, L F Deng, X M Tang Shi yan sheng wu xue bao 2000 new
Differential influence of nucleoside analog-resistance mutations K65R and L74V on the overall mutation rate and error specificity of human immunodeficiency virus type 1 reverse transcriptase. F S Shah, Kenneth A Curr, Monica E Hamburgh, M Parniak, Hiroyuki Mitsuya, J G Arnez, Vinayaka R Prasad The Journal of biological chemistry 2000 topics set
Identification of Escherichia coli dnaE (polC) mutants with altered sensitivity to 2',3'-dideoxyadenosine. K Hiratsuka, Linda J Reha-Krantz Journal of bacteriology 2000 new
Up-regulation of telomerase in primary cultured rat hepatocytes. K Nozawa, Y Kurumiya, A Yamamoto, Y Isobe, Motoshi Suzuki, Shonen Yoshida Journal of biochemistry 1999 new
Human CDC45 protein binds to minichromosome maintenance 7 protein and the p70 subunit of DNA polymerase alpha. I Kukimoto, H Igaki, T Kanda Eur J Biochem 1999 new
Replisome assembly at oriC, the replication origin of E. coli, reveals an explanation for initiation sites outside an origin. L Fang, Megan J Davey, Mike E O'Donnell Molecular cell 1999 topics set
DNA and protein interactions of the small subunit of herpes simplex virus type 1 DNA polymerase. C Franz, F J Kühn, Charles W Knopf Virology 1999 new
The fidelity of DNA polymerase beta during distributive and processive DNA synthesis. Wendy P Osheroff, H K Jung, William A Beard, Samuel H Wilson, Thomas A Kunkel The Journal of biological chemistry 1999 new
DNA polymerase beta expression differences in selected human tumors and cell lines. Deepak K Srivastava, I Husain, C L Arteaga, Samuel H Wilson Carcinogenesis 1999 new
Mutation enhancement by DINB1, a mammalian homologue of the Escherichia coli mutagenesis protein dinB. Tomoo Ogi, T Kato, T Kato, Haruo Ohmori Genes to cells : devoted to molecular & cellular mechanisms 1999 topics set
Involvement of phenylalanine 272 of DNA polymerase beta in discriminating between correct and incorrect deoxynucleoside triphosphates. Shu-Xia Li, Joseph A Vaccaro, Joann B Sweasy Biochemistry 1999 new
DNA polymerase II (polB) is involved in a new DNA repair pathway for DNA interstrand cross-links in Escherichia coli. M Berardini, Patricia L Foster, Edward L Loechler J Bacteriol 1999 new
"Action-at-a-distance" mutagenesis. 8-oxo-7, 8-dihydro-2'-deoxyguanosine causes base substitution errors at neighboring template sites when copied by DNA polymerase beta. E Efrati, G Tocco, R Eritja, Samuel H Wilson, Myron F Goodman The Journal of biological chemistry 1999 pols set
On the wagon--DNA polymerase joins "H-bonds anonymous". Myron F Goodman Nat Biotechnol 1999 new
The dinB gene encodes a novel E. coli DNA polymerase, DNA pol IV, involved in mutagenesis. Jérôme E Wagner, Petr Grúz, Su-Ryang Kim, Masami Yamada, Keiko Matsui, Robert P P Fuchs, Takehiko Nohmi Molecular cell 1999 complete Jérôme E Wagner*
Quality control PCR: a method for detecting inhibitors of Taq DNA polymerase. R A Reiss, B Rutz BioTechniques 1999 pols set
Effects of a high-affinity antibody fragment on DNA polymerase reactions near a (6-4) photoproduct site. H Kobayashi, K Sato, Y Komatsu, H Morioka, J D Stewart, Toshiki Tsurimoto, E Ohtsuka Photochem Photobiol 1999 new
Selection and characterization of HIV-1 variants resistant to the (+) and (-) enantiomers of 2'-deoxy-3'-oxa-4'-thiocytidine (dOTC). N Richar, Yudong Quan, H Salomon, M Hsu, J Bedard, P Richard Harrigan, R Rando, T Mansour, T L Bowlin, Mark A. Wainberg Antiviral therapy 1999 pols set
Action of a new mammalian DNA polymerase inhibitor, sulfoquinovosyldiacylglycerol. Keisuke Ohta, Yoshiyuki Mizushina, N Hirata, Masaharu Takemura, Fumio Sugawara, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi Biol Pharm Bull 1999 pols set
NMR structure of the chimeric hybrid duplex r(gcaguggc).r(gcca)d(CTGC) comprising the tRNA-DNA junction formed during initiation of HIV-1 reverse transcription. T Szyperski, Matthias Götte, M Billeter, E Perola, Luciano Cellai, H Heumann, K Wüthrich Journal of biomolecular NMR 1999 pols set
The mitochondrial p55 accessory subunit of human DNA polymerase gamma enhances DNA binding, promotes processive DNA synthesis, and confers N-ethylmaleimide resistance. Susan E Lim, Matthew J Longley, William C Copeland The Journal of biological chemistry 1999 partial results
A novel protein tag from herpes simplex virus type 1 DNA polymerase. U Schreiner, J Hansen, F J Kühn, Charles W Knopf Intervirology 1999 new
A phenotype for enigmatic DNA polymerase II: a pivotal role for pol II in replication restart in UV-irradiated Escherichia coli. Sneha Rangarajan, Roger Woodgate, Myron F Goodman Proceedings of the National Academy of Sciences of the United States of America 1999 new
Inhibition of Escherichia coli DNA polymerase-I by the anti-cancer drug cis-diaminedichloroplatinum(II): what roles do polymerases play in cis-platin-induced cytotoxicity? R K Duman, R T Heath, Rathindra N Bose FEBS letters 1999 pols set
UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V. M Tang, Xuan Shen, Ekaterina G Frank, Mike E O'Donnell, Roger Woodgate, Myron F Goodman Proceedings of the National Academy of Sciences of the United States of America 1999 topics set
The accessory subunit of Xenopus laevis mitochondrial DNA polymerase gamma increases processivity of the catalytic subunit of human DNA polymerase gamma and is related to class II aminoacyl-tRNA synthetases. José A Carrodeguas, Ryuji Kobayashi, Susan E Lim, William C Copeland, Daniel F Bogenhagen Molecular and cellular biology 1999 new
Overexpression of DNA polymerase beta: a genomic instability enhancer process. Yvan Canitrot, M Frechet, Laurence Servant, Christophe Cazaux, Jean-Sébastien Hoffmann FASEB J 1999 new
Harbinatic acid, a novel and potent DNA polymerase beta inhibitor from Hardwickia binata. Jing-Zhen Deng, Shelley R Starck, Sidney M Hecht, C F Ijames, M E Hemling J Nat Prod 1999 new
Mutation S543N in the thumb subdomain of the Taq DNA polymerase large fragment suppresses pausing associated with the template structure. K B Ignatov, A A Bashirova, A I Miroshnikov, V M Kramarov FEBS letters 1999 pols set
Functional interactions of a homolog of proliferating cell nuclear antigen with DNA polymerases in Archaea. Isaac K O Cann, Sonoko Ishino, I Hayashi, Kayoko Komori, H Toh, Kosuke Morikawa, Yoshizumi Ishino J Bacteriol 1999 new
Sensitized photomodification of mammalian DNA polymerase beta. A new approach for highly selective affinity labeling of polymerases. Dmitry M Kolpashchikov, Nadejda I Rechkunova, M I Dobrikov, Svetlana N Khodyreva, Natalia A Lebedeva, Olga I Lavrik FEBS letters 1999 pols set
Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta. Robert E Johnson, Satya Prakash, Louise Prakash Science 1999 new
Stavudine resistance: an update on susceptibility following prolonged therapy. P F Lin, C J González, B Griffith, G Friedland, V Calvez, F Ferchal, Raymond F Schinazi, D H Shepp, A B Ashraf, Mark A. Wainberg, V Soriano, John W Mellors, R J Colonno Antiviral therapy 1999 pols set
DNA polymerase-associated lectin (DPAL) and its binding to the galactose-containing glycoconjugate of the replication complex. T J Kelley, T St Amand, J M Groll, S Ray, S Basu Biosci Rep 1999 new
Human immunodeficiency virus type 1 expressing the lamivudine-associated M184V mutation in reverse transcriptase shows increased susceptibility to adefovir and decreased replication capability in vitro. Michael D Miller, K E Anton, A S Mulato, P D Lamy, J M Cherrington J Infect Dis 1999 new
Gene walking by PCR amplification of short fragments from Taq DNA polymerase--modified P1 plasmid DNA and TA cloning. B Baury, D Masson, P Lustenberger, M G Denis BioTechniques 1999 pols set
Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli. C A Brautigam, Siyang Sun, J A Piccirilli, Thomas A Steitz Biochemistry 1999 topics set
Mechanistic studies comparing the incorporation of (+) and (-) isomers of 3TCTP by HIV-1 reverse transcriptase. Joy Y Feng, Karen S Anderson Biochemistry 1999 new
Mode analysis of a fatty acid molecule binding to the N-terminal 8-kDa domain of DNA polymerase beta. A 1:1 complex and binding surface. Yoshiyuki Mizushina, Tadayasu Ohkubo, T Date, Tsuyoshi Yamaguchi, Mineo Saneyoshi, Fumio Sugawara, Kengo Sakaguchi The Journal of biological chemistry 1999 pols set
Specific interaction between DNA polymerase II (PolD) and RadB, a Rad51/Dmc1 homolog, in Pyrococcus furiosus. I Hayashi, Kosuke Morikawa, Yoshizumi Ishino Nucleic acids research 1999 new
hRAD30 mutations in the variant form of xeroderma pigmentosum. Robert E Johnson, Christine M Kondratick, Satya Prakash, Louise Prakash Science (New York, N.Y.) 1999 new
A mechanism of AZT resistance: an increase in nucleotide-dependent primer unblocking by mutant HIV-1 reverse transcriptase. Peter R Meyer, Suzanne E Matsuura, A M Mian, Antero G So, Walter A Scott Molecular cell 1999 topics set
Structure of taq DNA polymerase shows a new orientation for the structure-specific nuclease domain. U K Urs, R Murali, H M Krishna Murthy Acta Crystallogr D Biol Crystallogr 1999 pols set
Residues in the alphaH and alphaI helices of the HIV-1 reverse transcriptase thumb subdomain required for the specificity of RNase H-catalyzed removal of the polypurine tract primer. M D Powell, William A Beard, Katarzyna Bebenek, K J Howard, Stuart F J Le Grice, Thomas A Darden, Thomas A Kunkel, Samuel H Wilson, J G Levin The Journal of biological chemistry 1999 pols set
Inactivation of Escherichia coli DnaA protein by DNA polymerase III and negative regulations for initiation of chromosomal replication. T Katayama, K Sekimizu Biochimie 1999 new
HIV resistance to zidovudine: the role of pyrophosphorolysis. Dominique Arion, Michael A. Parniak Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 1999 pols set
Effects of exonuclease activity and nucleotide selectivity of the herpes simplex virus DNA polymerase on the fidelity of DNA replication in vivo. Ying T Hwang, B Y Liu, C Y Hong, E J Shillitoe, Charles B C Hwang J Virol 1999 new
In vitro induction of human immunodeficiency virus type 1 variants resistant to phosphoralaninate prodrugs of Z-methylenecyclopropane nucleoside analogues. K Yoshimura, R Feldman, Eiichi N Kodama, M F Kavlick, Y L Qiu, J Zemlicka, Hiroyuki Mitsuya Antimicrobial agents and chemotherapy 1999 pols set
Characterization of the DNA polymerase and thymidine kinase genesof herpes simplex virus isolates from AIDS patients in whom acyclovirand foscarnet therapy sequentially failed. I Schmit, Guy Boivin J Infect Dis 1999 new
Steady-state kinetic characterization of RB69 DNA polymerase mutants that affect dNTP incorporation. Guangwei Yang, T Lin, J Karam, William H Konigsberg Biochemistry 1999 complete
Inhibition of eukaryotic dna polymerase alpha by persimmon (Diospyros kaki) extract and related polyphenols. H Umekawa, Y Takada, Yasuhiro Furuichi, Tomonori Takahashi, Y Achiwa, T Komiya, Shonen Yoshida Biochem Mol Biol Int 1999 new
Thermostable DNA polymerase from Thermus thermophilus B35: cloning, sequence analysis, and gene expression. A G Akishev, Nadejda I Rechkunova, Natalia A Lebedeva, Olga I Lavrik, S K Degtyarev Biochemistry (Mosc) 1999 new
Functional mutation of DNA polymerase beta found in human gastric cancer--inability of the base excision repair in vitro. A Iwanaga, M Ouchida, K Miyazaki, K Hori, T Mukai Mutation research 1999 pols set
Regulation of catalytic activity and processivity of human telomerase. Daekyu Sun, C C Lopez-Guajardo, J Quada, Laurence H Hurley, D D Von Hoff Biochemistry 1999 new
Cyclosporin A inhibits Ca2+-mediated upregulation of the DNA repair enzyme DNA polymerase beta in human peripheral blood mononuclear cells. C Ahlers, S Kreideweiss, A Nordheim, A Rühlmann Eur J Biochem 1999 new
6-Anilinouracil-based inhibitors of Bacillus subtilis DNA polymerase III: antipolymerase and antimicrobial structure-activity relationships based on substitution at uracil N3. Paul M Tarantino, Chengxin Zhi, Joseph J Gambino, George E Wright, Neal C Brown J Med Chem 1999 new
A mutation detected in DNA polymerase delta cDNA from Novikoff hepatoma cells correlates with abnormal catalytic properties of the enzyme. O Popanda, T Flohr, G Fox, H W Thielmann J Cancer Res Clin Oncol 1999 new
Age-dependent changes in DNA polymerase fidelity and proofreading activity during cellular aging. M Fukuda, Takahiko Taguchi, Mochihiko Ohashi Mech Ageing Dev 1999 new
The human REV1 gene codes for a DNA template-dependent dCMP transferase. W Lin, Hongkui Xin, Yongqing Zhang, Xiaoming Wu, Fenghua Yuan, Zhengqiang Wang Nucleic acids research 1999 topics set
Mitochondrial DNA polymerase gamma deficiency and mtDNA depletion in a child with Alpers' syndrome. R K Naviaux, W L Nyhan, B A Barshop, J Poulton, D Markusic, N C Karpinski, R H Haas Ann Neurol 1999 new
Direct interaction of proliferating cell nuclear antigen with the p125 catalytic subunit of mammalian DNA polymerase delta. Peiming Zhang, J Y Mo, A Perez, A Leon, Lingfeng Liu, Nayef Mazloum, H Xu, Marietta Y W T Lee The Journal of biological chemistry 1999 pols set
Tyrosine 222, a member of the YXDD motif of MuLV RT, is catalytically essential and is a major component of the fidelity center. Neerja Kaushik, Kamalendra Singh, I Alluru, Mukund J Modak Biochemistry 1999 pols set
Analysis of the role of glutamine 190 in the catalytic mechanism of murine leukemia virus reverse transcriptase. J Jin, Neerja Kaushik, Kamalendra Singh, Mukund J Modak The Journal of biological chemistry 1999 new
Oligomeric structures of the phage phi29 histone-like protein p6. A M Abril, S Marco, José L Carrascosa, Margarita Salas, José M Hermoso Journal of molecular biology 1999 pols set
A plethora of lesion-replicating DNA polymerases. Roger Woodgate Genes Dev 1999 new
Inhibition of human immunodeficiency virus type (HIV-1) replication by some diversely functionalized spirocyclopropyl derivatives. Myriam Witvrouw, Christophe Pannecouque, Erik De Clercq, E Fernández-Alvarez, J L Marco Archiv der Pharmazie 1999 pols set
HIV-1 reverse transcription: a brief overview focused on structure-function relationships among molecules involved in initiation of the reaction. Matthias Götte, Xincang Li, Mark A. Wainberg Archives of biochemistry and biophysics 1999 pols set
Mutator phenotype of BCR--ABL transfected Ba/F3 cell lines and its association with enhanced expression of DNA polymerase beta. Yvan Canitrot, D Lautier, Guy Laurent, Mathilde Fréchet, A Ahmed, A G Turhan, B Salles, Christophe Cazaux, Jean-Sébastien Hoffmann Oncogene 1999 new
Functional interactions of mitochondrial DNA polymerase and single-stranded DNA-binding protein. Template-primer DNA binding and initiation and elongation of DNA strand synthesis. Carol L Farr, Yazhen Wang, Laurie S Kaguni The Journal of biological chemistry 1999 new
Spt16 and Pob3 of Saccharomyces cerevisiae form an essential, abundant heterodimer that is nuclear, chromatin-associated, and copurifies with DNA polymerase alpha. J Wittmeyer, L Joss, T Formosa Biochemistry 1999 new
Interaction of Escherichia coli DNA polymerase I (Klenow fragment) with primer-templates containing N-acetyl-2-aminofluorene or N-2-aminofluorene adducts in the active site. Leonid Dzantiev, Louis J Romano The Journal of biological chemistry 1999 pols set
Primer length dependence of binding of DNA polymerase I Klenow fragment to template-primer complexes containing site-specific bulky lesions. Olga Rechkoblit, Shantu Amin, Nicholas E Geacintov Biochemistry 1999 pols set
Alteration of hMSH2 and DNA polymerase beta genes in breast carcinomas and fibroadenomas. Nandan Bhattacharyya, Huan-Chao Chen, S Grundfest-Broniatowski, Sanjeev Banerjee Biochem Biophys Res Commun 1999 new
Delayed cytotoxicity of 6-mercaptopurine is compatible with mitotic death caused by DNA damage due to incorporation of 6-thioguanine into DNA as 6-thioguanine nucleotide. H Inamochi, M Higashigawa, Y Shimono, T Nagata, D C Cao, X Y Mao, T M'soka, H Hori, H Kawasaki, M Sakurai J Exp Clin Cancer Res 1999 topics set
Reconstitution of proliferating cell nuclear antigen-dependent repair of apurinic/apyrimidinic sites with purified human proteins. Yoshihiro Matsumoto, K Kim, Jerard Hurwitz, R Gary, D S Levin, A E Tomkinson, M S Park The Journal of biological chemistry 1999 new
An open and closed case for all polymerases. Sylvie Doublié, M R Sawaya, Tom Ellenberger Structure (London, England : 1993) 1999 pols set
DNA polymerases: structural diversity and common mechanisms. Thomas A Steitz The Journal of biological chemistry 1999 topics set
Phage phi29 terminal protein residues Asn80 and Tyr82 are recognition elements of the replication origins. B Illana, José María Lázaro, C Gutiérrez, Wilfried J J Meijer, Luis Blanco, Margarita Salas The Journal of biological chemistry 1999 pols set
Nucleosides and nucleotides. 185. Synthesis and biological activities of 4'alpha-C-branched-chain sugar pyrimidine nucleosides. M Nomura, S Shuto, M Tanaka, T Sasaki, S Mori, S Shigeta, Akira Matsuda J Med Chem 1999 new
A new DNA polymerase species from Drosophila melanogaster: a probable mus308 gene product. Masahiko Oshige, N Aoyagi, P V Harris, K C Burtis, Kengo Sakaguchi Mutation research 1999 new
A family of insertion mutations between codons 67 and 70 of human immunodeficiency virus type 1 reverse transcriptase confer multinucleoside analog resistance. Brendan A Larder, Stuart Bloor, S D Kemp, Kurt Hertogs, R L Desmet, V Miller, M Sturmer, Schlomo Staszewski, Jingshan Ren, David K Stammers, David I Stuart, Rudi Pauwels Antimicrob Agents Chemother 1999 topics set
Antitumor activity of 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl) adenine, a novel deoxyadenosine analog, against human colon tumor xenografts by oral administration. Tomosaburo Takahashi, J Kanazawa, S Akinaga, T Tamaoki, M Okabe Cancer chemotherapy and pharmacology 1999 new
Temporal coordination between initiation of HIV (+)-strand DNA synthesis and primer removal. Matthias Götte, G Maier, A M Onori, Luciano Cellai, Mark A. Wainberg, H Heumann The Journal of biological chemistry 1999 pols set
Characterization and application to hot start PCR of neutralizing monoclonal antibodies against KOD DNA polymerase. H Mizuguchi, M Nakatsuji, Shinsuke Fujiwara, Masahiro Takagi, Tadayuki Imanaka J Biochem 1999 new
Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius. K P Hopfner, A Eichinger, R A Engh, F Laue, W Ankenbauer, R Huber, B Angerer Proceedings of the National Academy of Sciences of the United States of America 1999 partial results
Comparison of the 5' nuclease activities of taq DNA polymerase and its isolated nuclease domain. V Lyamichev, M A Brow, V E Varvel, J E Dahlberg Proceedings of the National Academy of Sciences of the United States of America 1999 pols set
Purification and properties of Thermus filiformis DNA polymerase expressed in Escherichia coli. Jeong Jin Choi, S E Jung, H K Kim, Suk-Tae Kwon Biotechnol Appl Biochem 1999 new
Nucleosides and nucleotides. 183. Synthesis of 4'alpha-branched thymidines as a new type of antiviral agent. I Sugimoto, S Shuto, S Mori, S Shigeta, Akira Matsuda Bioorganic & medicinal chemistry letters 1999 new
Phosphorylation and dephosphorylation of the B subunit of DNA polymerase alpha-primase complex in the early embryogenesis of Drosophila. Kazufumi Kuroda, R Ueda Biochem Biophys Res Commun 1999 new
cDNA and structural organization of the gene Pole1 for the mouse DNA polymerase epsilon catalytic subunit. D Huang, R Knuuti, H Palosaari, Helmut Pospiech, Juhani E Syväoja Biochimica et biophysica acta 1999 new
Crystal structure of an archaebacterial DNA polymerase. Yaofeng Zhao, David Jeruzalmi, I Moarefi, L Leighton, R Lasken, John Kuriyan Structure (London, England : 1993) 1999 partial results
Structural origins of the exonuclease resistance of a zwitterionic RNA. M Teplova, S T Wallace, V Tereshko, G Minasov, A M Symons, P D Cook, M Manoharan, Martin Egli Proceedings of the National Academy of Sciences of the United States of America 1999 topics set
Development of a new DNA sequencing method: 3'-ester cleavage catalyzed by Taq DNA polymerase. I Rasolonjatovo, S R Sarfati Nucleosides Nucleotides 1999 pols set
DNA polymerase beta inhibitors from Sandoricum koetjape. Di-An Sun, Shelley R Starck, E P Locke, Sidney M Hecht J Nat Prod 1999 new
HIV-1 reverse transcriptase is phosphorylated in vitro and in a cellular system. H Idriss, S Kawa, Z Damuni, E B Thompson, Samuel H Wilson The international journal of biochemistry & cell biology 1999 pols set
Sensitivity of bacteriophage RB69 DNA polymerase to N2-(p-n-butylphenyl)-2'-deoxyguanosine nucleotides. J M Stattel, George E Wright Nucleosides Nucleotides 1999 pols set
Analysis of porcine cytomegalovirus DNA polymerase by consensus primer PCR. V Rupasinghe, T Tajima, K Maeda, K Iwatsuki-Horimoto, S Sugii, T Horimoto J Vet Med Sci 1999 new
In vitro selection of sequence contexts which enhance bypass of abasic sites and tetrahydrofuran by T4 DNA polymerase holoenzyme. Zafer Hatahet, Mian Zhou, Linda J Reha-Krantz, Hiroshi Ide, S W Morrical, Susan S Wallace Journal of molecular biology 1999 pols set
The 3'-->5' exonucleases of DNA polymerases delta and epsilon and the 5'-->3' exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiae. H T Tran, Dmitry A Gordenin, Michael A Resnick Molecular and cellular biology 1999 new
Novel human and mouse homologs of Saccharomyces cerevisiae DNA polymerase eta. John P McDonald, V Rapić-Otrin, J A Epstein, Bernard C Broughton, X Wang, Alan R Lehmann, D J Wolgemuth, Roger Woodgate Genomics 1999 pols set
Pyrrolobenzoxazepinone derivatives as non-nucleoside HIV-1 RT inhibitors: further structure-activity relationship studies and identification of more potent broad-spectrum HIV-1 RT inhibitors with antiviral activity. Giuseppe Campiani, Elena Morelli, M Fabbrini, Vito Nacci, Giovanni Greco, Ettore Novellino, Anna Ramunno, Giovanni Maga, Silvio Spadari, G Caliendo, Alberto Bergamini, E Faggioli, I Uccella, F Bolacchi, Stefano Marini, Massimo Coletta, A Nacca, S Caccia Journal of medicinal chemistry 1999 pols set
Detection of tandem CC-->TT mutations induced by oxygen radicals using mutation-specific PCR. T G Newcomb, K J Allen, L Tkeshelashvili, Lawrence A Loeb Mutation research 1999 new
Studies of the genomic RNA of leukosis viruses: implications for RNA dimerization. B A Ortiz-Conde, Stephen H Hughes Journal of virology 1999 new
Crystallographic analysis of the binding modes of thiazoloisoindolinone non-nucleoside inhibitors to HIV-1 reverse transcriptase and comparison with modeling studies. Jingshan Ren, R M Esnouf, Andrew L Hopkins, David I Stuart, David K Stammers J Med Chem 1999 topics set
The Escherichia coli SOS mutagenesis proteins UmuD and UmuD' interact physically with the replicative DNA polymerase. Mark D Sutton, T Opperman, Graham C Walker Proceedings of the National Academy of Sciences of the United States of America 1999 new
DNA polymerase epsilon catalytic domains are dispensable for DNA replication, DNA repair, and cell viability. Tapio Kesti, K Flick, S Keränen, Juhani E Syväoja, Curt Wittenberg Molecular cell 1999 new
Analysis of the essential functions of the C-terminal protein/protein interaction domain of Saccharomyces cerevisiae pol epsilon and its unexpected ability to support growth in the absence of the DNA polymerase domain. Rajiv Dua, Daniel L Levy, Judith L Campbell The Journal of biological chemistry 1999 new
Long patch base excision repair with purified human proteins. DNA ligase I as patch size mediator for DNA polymerases delta and epsilon. Barbara Pascucci, M Stucki, Z O Jónsson, Eugenia Dogliotti, Ulrich Hübscher The Journal of biological chemistry 1999 new
Inhibitors of DNA polymerase III as novel antimicrobial agents against gram-positive eubacteria. Paul M Tarantino, Chengxin Zhi, George E Wright, Neal C Brown Antimicrob Agents Chemother 1999 new
The linker region between the helicase and primase domains of the bacteriophage T7 gene 4 protein is critical for hexamer formation. S Guo, Stanley Tabor, Charles C Richardson The Journal of biological chemistry 1999 pols set
A novel genotype encoding a single amino acid insertion and five other substitutions between residues 64 and 74 of the HIV-1 reverse transcriptase confers high-level cross-resistance to nucleoside reverse transcriptase inhibitors. Abacavir CNA2007 International Study Group. A Rakik, M Ait-Khaled, P Griffin, T A Thomas, M Tisdale, Jörg-Peter Kleim J Acquir Immune Defic Syndr 1999 topics set
Interstrain variation in the human cytomegalovirus DNA polymerase sequence and its effect on genotypic diagnosis of antiviral drug resistance. Adult AIDS Clinical Trials Group CMV Laboratories. Sunwen Chou, Nell S Lurain, Adriana Weinberg, G Y Cai, P L Sharma, C S Crumpacker Antimicrob Agents Chemother 1999 pols set
Detection of mutation(s) or polymorphic loci in the genome of experimental animal and human cancer tissues by RAPD/AP-PCR depend on DNA polymerase. K P Singh, D Roy Int J Oncol 1999 new
Synthesis and biological evaluation of 2',3'-didehydro-2',3'- dideoxy-5-fluorocytidine (D4FC) analogues: discovery of carbocyclic nucleoside triphosphates with potent inhibitory activity against HIV-1 reverse transcriptase. Junxing Shi, J J McAtee, S Schlueter Wirtz, P Tharnish, A Juodawlkis, Dennis C Liotta, Raymond F Schinazi J Med Chem 1999 topics set
Efficient processing of DNA ends during yeast nonhomologous end joining. Evidence for a DNA polymerase beta (Pol4)-dependent pathway. T E Wilson, M R Lieber The Journal of biological chemistry 1999 new
Novel DNA polymerases offer clues to the molecular basis of mutagenesis. Errol C Friedberg, Valerie L Gerlach Cell 1999 new
A neutralizing antibody against human DNA polymerase epsilon inhibits cellular but not SV40 DNA replication. Helmut Pospiech, I Kursula, Waleed Abdel-Aziz, Linda Malkas, L Uitto, M Kastelli, M Vihinen-Ranta, S Eskelinen, Juhani E Syväoja Nucleic acids research 1999 pols set
Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acids. Stefan G Sarafianos, Kalyan Das, Arthur D Clark, Jianping Ding, Paul L Boyer, Stephen H Hughes, Edward Arnold Proceedings of the National Academy of Sciences of the United States of America 1999 topics set
Guanine-rich telomeric sequences stimulate DNA polymerase activity in vitro. J Ying, R K Bradley, L B Jones, M S Reddy, D T Colbert, R E Smalley, S H Hardin Biochemistry 1999 new
The Saccharomyces cerevisiae protein YJR043C (Pol32) interacts with the catalytic subunit of DNA polymerase alpha and is required for cell cycle progression in G2/M. Meng-Er Huang, B Le Douarin, C Henry, Francis Galibert Mol Gen Genet 1999 new
Poliovirus RNA-dependent RNA polymerase (3Dpol) is sufficient for template switching in vitro. Jamie J Arnold, Craig E Cameron The Journal of biological chemistry 1999 new
Vaccinia virus DNA polymerase promotes DNA pairing and strand-transfer reactions. David O Willer, M J Mann, Weiming Zhang, David H Evans Virology 1999 complete David H Evans*
Archaeal DNA replication: identifying the pieces to solve a puzzle. Isaac K O Cann, Yoshizumi Ishino Genetics 1999 new
Dye structure affects Taq DNA polymerase terminator selectivity. J W Brandis Nucleic acids research 1999 pols set
Determination of human DNA polymerase utilization for the repair of a model ionizing radiation-induced DNA strand break lesion in a defined vector substrate. T A Winters, P S Russell, M Kohli, M E Dar, R D Neumann, T J Jorgensen Nucleic acids research 1999 pols set
Insertion of two amino acids combined with changes in reverse transcriptase containing tyrosine-215 of HIV-1 resistant to multiple nucleoside analogs. J J de Jong, J Goudsmit, V V Lukashov, M E Hillebrand, E Baan, R Huismans, Sven A Danner, J H ten Veen, F de Wolf, Suzanne Jurriaans Aids 1999 topics set
DNA structure and polymerase fidelity. Y Timsit Journal of molecular biology 1999 topics set
Requirement of DNA polymerase activity of yeast Rad30 protein for its biological function. Robert E Johnson, Satya Prakash, Louise Prakash The Journal of biological chemistry 1999 new
[New reagents for affinity modification of biopolymers. Photoaffinity modification of Tte-DNA polymerase]. Dmitry M Kolpashchikov, A L Zakharenko, Sergey V Dezhurov, Nadejda I Rechkunova, Svetlana N Khodyreva, S Kh Degtiarev, V V Litvak, Olga I Lavrik Bioorg Khim 1999 new
Identification of transactivator and nuclear localization domains in the Epstein-Barr virus DNA polymerase accessory protein, BMRF1. Q Zhang, E Holley-Guthrie, D Dorsky, S Kenney The Journal of general virology 1999 new
Abasic template lesions are strong chain terminators for DNA primase but not for DNA polymerase alpha during the synthesis of new DNA strands. L K Zerbe, Myron F Goodman, E Efrati, Robert D Kuchta Biochemistry 1999 new
A novel family of DNA-polymerase-associated B subunits. M Mäkiniemi, Helmut Pospiech, S Kilpeläinen, Maarit Jokela, M Vihinen, Juhani E Syväoja Trends in biochemical sciences 1999 new
Architecture of the active DNA polymerase delta.proliferating cell nuclear antigen.template-primer complex. Dmitry Ju Mozzherin, Cheng-Keat Tan, Kathleen M Downey, Paul A Fisher The Journal of biological chemistry 1999 new
Affinity maturation of a Taq DNA polymerase specific affibody by helix shuffling. E Gunneriusson, K Nord, M Uhlén, P Nygren Protein Eng 1999 pols set
Cells deficient in DNA polymerase beta are hypersensitive to alkylating agent-induced apoptosis and chromosomal breakage. Kirsten Ochs, Robert W Sobol, Samuel H Wilson, Bernd Kaina Cancer research 1999 new
[Corrective role of autonomous 3'--->5'-exonuclease in synthesis of DNA,catalyzed by DNA polymerase beta from rat liver]. Igor V Shevelev, N V Beliakova, T P Kravetskaia, N L Ronzhina, E A Smirnova, K Iu Tutaev, I I Sheveleva, V M Krutiakov Mol Biol (Mosk) 1999 new
Strand asymmetry of +1 frameshift mutagenesis at a homopolymeric run by DNA polymerase III holoenzyme of Escherichia coli. Masayuki Seki, Masahiro Tatsumi Akiyama, Yutaka Sugaya, Eiichi Ohtsubo, Hisaji Maki The Journal of biological chemistry 1999 pols set
3'-Azido-3'-deoxythymidine-resistant mutants of DNA polymerase beta identified by in vivo selection. Jessica L Kosa, Joann B Sweasy The Journal of biological chemistry 1999 new
DNA polymerase beta inhibitors from Baeckea gunniana. Jing-Zhen Deng, Shelley R Starck, Sidney M Hecht J Nat Prod 1999 new
Cloning and chromosomal mapping of the human DNA polymerase theta (POLQ), the eighth human DNA polymerase. Farida S Sharief, P J Vojta, P A Ropp, William C Copeland Genomics 1999 pols set
Polymerase chain reaction-based enzyme immunoassay for quantitation of telomerase activity: application to colorectal cancers. A J Cheng, R Tang, Ji-Yang Wang, J T Chang, T C Wang Japanese journal of cancer research : Gann 1999 new
Multiple competition reactions for RPA order the assembly of the DNA polymerase delta holoenzyme. Alexander Yuzhakov, Zvi Kelman, Jerard Hurwitz, Mike E O'Donnell The EMBO journal 1999 new
The Werner syndrome protein is involved in RNA polymerase II transcription. A S Balajee, A Machwe, Alfred May, M D Gray, J Oshima, G M Martin, J O Nehlin, R Brosh, D K Orren, Vilhelm A Bohr Mol Biol Cell 1999 new
Crystallographic studies on a family B DNA polymerase from hyperthermophilic archaeon Pyrococcus kodakaraensis strain KOD1. Hiroshi Hashimoto, Takehisa Matsumoto, Motomu Nishioka, T Yuasa, S Takeuchi, Tsuyoshi Inoue, Shinsuke Fujiwara, Masahiro Takagi, Tadayuki Imanaka, Yasushi Kai J Biochem 1999 new
Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. V Lohmann, F Körner, J Koch, U Herian, L Theilmann, R Bartenschlager Science 1999 new
Uniquely altered DNA replication fidelity conferred by an amino acid change in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase. D A Lewis, Katarzyna Bebenek, William A Beard, Samuel H Wilson, Thomas A Kunkel The Journal of biological chemistry 1999 pols set
Major subdomain rearrangement in HIV-1 reverse transcriptase simulated by molecular dynamics. M Madrid, A Jacobo-Molina, Jianping Ding, Edward Arnold Proteins 1999 pols set
Mechanism of action and in vitro activity of 1',3'-dioxolanylpurine nucleoside analogues against sensitive and drug-resistant human immunodeficiency virus type 1 variants. Z Gu, Mark A. Wainberg, N Nguyen-Ba, L L'Heureux, J M de Muys, T L Bowlin, R F Rando Antimicrobial agents and chemotherapy 1999 pols set
Resistance mutations selected in vivo under therapy with anti-HIV drug HBY 097 differ from resistance pattern selected in vitro. H Rübsamen-Waigmann, E Huguenel, A Shah, A Paessens, H J Ruoff, H von Briesen, A Immelmann, U Dietrich, Mark A. Wainberg Antiviral research 1999 pols set
Specification of regions of DNA replication initiation during embryogenesis in the 65-kilobase DNApolalpha-dE2F locus of Drosophila melanogaster. T Sasaki, T Sawado, Masamitsu Yamaguchi, T Shinomiya Molecular and cellular biology 1999 new
Role of DNA polymerase beta in the excision step of long patch mammalian base excision repair. Grigory L Dianov, Rajendra Prasad, Samuel H Wilson, Vilhelm A Bohr The Journal of biological chemistry 1999 new
Trading places on DNA--a three-point switch underlies primer handoff from primase to the replicative DNA polymerase. Alexander Yuzhakov, Zvi Kelman, Mike E O'Donnell Cell 1999 new
The thiocarboxanilide nonnucleoside inhibitor UC781 restores antiviral activity of 3'-azido-3'-deoxythymidine (AZT) against AZT-resistant human immunodeficiency virus type 1. G Borkow, Dominique Arion, Mark A. Wainberg, Michael A. Parniak Antimicrobial agents and chemotherapy 1999 pols set
[A study of a derivative of Taq DNA polymerase]. Jun Zhang, C N Ji, H S Du, Z H Zheng, Y M Mao Yi Chuan Xue Bao 1999 pols set
Improved production of gutted adenovirus in cells expressing adenovirus preterminal protein and DNA polymerase. D Hartigan-O'Connor, A Amalfitano, J S Chamberlain J Virol 1999 new
Lucidenic acid O and lactone, new terpene inhibitors of eukaryotic DNA polymerases from a basidiomycete, Ganoderma lucidum. Yoshiyuki Mizushina, N Takahashi, L Hanashima, Hiroyuki Koshino, Y Esumi, J Uzawa, Fumio Sugawara, Kengo Sakaguchi Bioorganic & medicinal chemistry 1999 new
The motif D loop of human immunodeficiency virus type 1 reverse transcriptase is critical for nucleoside 5'-triphosphate selectivity. Bruno Canard, Kajal Chowdhury, R Sarfati, Sylvie Doublié, Charles C Richardson The Journal of biological chemistry 1999 pols set
Deletion errors generated during replication of CAG repeats. L C Kroutil, Thomas A Kunkel Nucleic acids research 1999 new
Mutational and pH studies of the 3' --> 5' exonuclease activity of bacteriophage T4 DNA polymerase. E Elisseeva, Subhrangsu S Mandal, Linda J Reha-Krantz The Journal of biological chemistry 1999 complete
Emergence of zidovudine and multidrug-resistance mutations in the HIV-1 reverse transcriptase gene in therapy-naive patients receiving stavudine plus didanosine combination therapy. STADI Group. I Pellegrin, J Izopet, J Reynes, M Denayrolles, Brigitte Montes, J L Pellegrin, P Massip, J Puel, H Fleury, Michel Segondy Aids 1999 topics set
Hydroxyurea potentiates the antiherpesvirus activities of purine and pyrimidine nucleoside and nucleoside phosphonate analogs. Johan Neyts, Erik De Clercq Antimicrobial agents and chemotherapy 1999 new
Side chains that influence fidelity at the polymerase active site of Escherichia coli DNA polymerase I (Klenow fragment). Dana T Minnick, Katarzyna Bebenek, Wendy P Osheroff, Robert M Turner, Mekbib Astatke, Lingfeng Liu, Thomas A Kunkel, Catherine M Joyce The Journal of biological chemistry 1999 pols set
Mutations in the primer grip region of HIV reverse transcriptase can increase replication fidelity. M Wisniewski, C Palaniappan, Z Fu, Stuart F J Le Grice, P Fay, Robert A Bambara The Journal of biological chemistry 1999 pols set
New human immunodeficiency virus, type 1 reverse transcriptase (HIV-1 RT) mutants with increased fidelity of DNA synthesis. Accuracy, template binding, and processivity. Baek Kim, J C Ayran, S G Sagar, Elinor T Adman, S M Fuller, N H Tran, J Horrigan The Journal of biological chemistry 1999 pols set
Identification of the acidic residues in the active site of DNA polymerase III. Arthur E Pritchard, Charles S McHenry Journal of molecular biology 1999 new
Single d(GpG)/cis-diammineplatinum(II) adduct-induced inhibition of DNA polymerization. Zucai Suo, S J Lippard, Kenneth A Johnson Biochemistry 1999 pols set
Interactions of DNA with human DNA primase monitored with photoactivatable cross-linking agents: implications for the role of the p58 subunit. B Arezi, B W Kirk, William C Copeland, R D Kuchta Biochemistry 1999 new
Similarities and differences in the RNase H activities of human immunodeficiency virus type 1 reverse transcriptase and Moloney murine leukemia virus reverse transcriptase. Hong Qiang Gao, Stefan G Sarafianos, Edward Arnold, Stephen H Hughes Journal of molecular biology 1999 pols set
Effect of DNA polymerases and high mobility group protein 1 on the carrier ligand specificity for translesion synthesis past platinum-DNA adducts. Alexandra Vaisman, Susan E Lim, S M Patrick, William C Copeland, David C Hinkle, J J Turchi, Stephen G Chaney Biochemistry 1999 pols set
The immunosuppressive agent mycophenolate mofetil markedly potentiates the activity of lobucavir [1R(1alpha,2beta,3alpha)]-9-[2,3-bis(hydroxymethyl)cyclobutyl]guanine against different herpes viruses. Johan Neyts, Erik De Clercq Transplantation 1999 new
Structural basis for initiation of transcription from an RNA polymerase-promoter complex. G M Cheetham, David Jeruzalmi, Thomas A Steitz Nature 1999 new
Molecular basis for the enantioselectivity of HIV-1 reverse transcriptase: role of the 3'-hydroxyl group of the L-(beta)-ribose in chiral discrimination between D- and L-enantiomers of deoxy- and dideoxy-nucleoside triphosphate analogs. Giovanni Maga, Mario Amacker, Ulrich Hübscher, G Gosselin, J L Imbach, C Mathé, A Faraj, J P Sommadossi, Silvio Spadari Nucleic acids research 1999 topics set
Quantitation of fluorescent nucleotide incorporation by capillary gel electrophoresis and laser-induced fluorescence detection. K A Cruickshank Anal Biochem 1999 topics set
Urea-PETT compounds as a new class of HIV-1 reverse transcriptase inhibitors. 3. Synthesis and further structure-activity relationship studies of PETT analogues. M Högberg, Christer Sahlberg, P Engelhardt, Rolf Noréen, J Kangasmetsä, N G Johansson, Bo Oberg, L Vrang, Haijiang Zhang, B L Sahlberg, Torsten Unge, S Lövgren, Kerstin Fridborg, K Bäckbro J Med Chem 1999 topics set
The accessory subunit of mtDNA polymerase shares structural homology with aminoacyl-tRNA synthetases: implications for a dual role as a primer recognition factor and processivity clamp. Li Fan, P C Sanschagrin, Laurie S Kaguni, L A Kuhn Proceedings of the National Academy of Sciences of the United States of America 1999 pols set
Bridging the gap: a family of novel DNA polymerases that replicate faulty DNA. Robert E Johnson, M Todd Washington, Satya Prakash, Louise Prakash Proceedings of the National Academy of Sciences of the United States of America 1999 new
Studies on the interactions between human replication factor C and human proliferating cell nuclear antigen. G Zhang, E Gibbs, Zvi Kelman, Mike E O'Donnell, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1999 new
Fidelity and processivity of Saccharomyces cerevisiae DNA polymerase eta. M Todd Washington, Robert E Johnson, Satya Prakash, Louise Prakash The Journal of biological chemistry 1999 partial results
DNA polymerase beta inhibitors from Tetracera boiviniana. J Ma, Shelley R Starck, Sidney M Hecht J Nat Prod 1999 new
Base substitution specificity of DNA polymerase beta depends on interactions in the DNA minor groove. Wendy P Osheroff, William A Beard, Samuel H Wilson, Thomas A Kunkel The Journal of biological chemistry 1999 new
Replication slippage of different DNA polymerases is inversely related to their strand displacement efficiency. D Canceill, Enrique Viguera, S Dusko Ehrlich The Journal of biological chemistry 1999 topics set
Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene. K Drotschmann, Alan B Clark, H T Tran, Michael A Resnick, Dmitry A Gordenin, Thomas A Kunkel Proceedings of the National Academy of Sciences of the United States of America 1999 new
The base substitution fidelity of HIV-1 reverse transcriptase on DNA and RNA templates probed with 8-oxo-deoxyguanosine triphosphate. Katarzyna Bebenek, J C Boyer, Thomas A Kunkel Mutation research 1999 pols set
Lethal mutagenesis of HIV with mutagenic nucleoside analogs. Lawrence A Loeb, J M Essigmann, F Kazazi, Jun Zhang, K D Rose, J I Mullins Proceedings of the National Academy of Sciences of the United States of America 1999 pols set
Susceptibility of lamivudine-resistant hepatitis B virus to other reverse transcriptase inhibitors. S K Ono-Nita, Norihisa Kato, Yasushi Shiratori, K H Lan, Hiromi Yoshida, F J Carrilho, Masao Omata The Journal of clinical investigation 1999 new
Explanation of pre-steady-state kinetics and decreased burst amplitude of HIV-1 reverse transcriptase at sites of modified DNA bases with an additional, nonproductive enzyme-DNA-nucleotide complex. L L Furge, F Peter Guengerich Biochemistry 1999 pols set
Targeted expression of the DNA binding domain of DRE-binding factor, a Drosophila transcription factor, attenuates DNA replication of the salivary gland and eye imaginal disc. Fumiko Hirose, Masamitsu Yamaguchi, Akio Matsukage Molecular and cellular biology 1999 new
The role of Pr55(gag) in the annealing of tRNA3Lys to human immunodeficiency virus type 1 genomic RNA. S Cen, Yangxin Huang, A Khorchid, J L Darlix, Mark A. Wainberg, Lawrence Kleiman Journal of virology 1999 pols set
Mismatch extension by Escherichia coli DNA polymerase III holoenzyme. P T Pham, M W Olson, Charles S McHenry, Roel M Schaaper The Journal of biological chemistry 1999 pols set
Analysis of unassisted translesion replication by the DNA polymerase III holoenzyme. Guy Tomer, Zvi Livneh Biochemistry 1999 pols set
DNA polymerase activity in encysting Entamoeba invadens. A Makioka, M Kumagai, H Ohtomo, Susumu Kobayashi, Toshifumi Takeuchi Parasitol Res 1999 new
The mutagenesis protein UmuC is a DNA polymerase activated by UmuD', RecA, and SSB and is specialized for translesion replication. N B Reuven, Gali Arad, Ayelet Maor-Shoshani, Zvi Livneh The Journal of biological chemistry 1999 partial results
Two DNA polymerase sliding clamps from the thermophilic archaeon Sulfolobus solfataricus. Mariarita De Felice, C W Sensen, R L Charlebois, Mosè Rossi, Francesca M Pisani Journal of molecular biology 1999 new
Probing interactions between HIV-1 reverse transcriptase and its DNA substrate with backbone-modified nucleotides. Andreas Marx, M Spichty, Mario Amacker, U Schwitter, Ulrich Hübscher, Thomas A Bickle, Giovanni Maga, Bernd Giese Chemistry & biology 1999 pols set
Isolation and characterization of a split B-type DNA polymerase from the archaeon Methanobacterium thermoautotrophicum deltaH. Zvi Kelman, S Pietrokovski, Jerard Hurwitz The Journal of biological chemistry 1999 new
[DNA polymerase alpha-DNA primase: structure and function]. Rashid O Anarbaev, I A Lokhova, Olga I Lavrik Mol Biol (Mosk) 1999 new
Anti-human immunodeficiency virus type 1 activity, intracellular metabolism, and pharmacokinetic evaluation of 2'-deoxy-3'-oxa-4'-thiocytidine. J M de Muys, H Gourdeau, N Nguyen-Ba, D L Taylor, P S Ahmed, T Mansour, C Locas, N Richard, Mark A. Wainberg, R F Rando Antimicrobial agents and chemotherapy 1999 pols set
Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation. Yingqian Li, V Mitaxov, Gabriel Waksman Proceedings of the National Academy of Sciences of the United States of America 1999 topics set
The E249K mutator mutant of DNA polymerase beta extends mispaired termini. Jessica L Kosa, Joann B Sweasy The Journal of biological chemistry 1999 new
Nucleolar protein B23.1 binds to retinoblastoma protein and synergistically stimulates DNA polymerase alpha activity. Masaharu Takemura, K Sato, M Nishio, Tetsu Akiyama, H Umekawa, Shonen Yoshida J Biochem 1999 new
Effective treatment of murine leukemia with antisense poly-2'O-(2,4-dinitrophenyl)-oligoribonucleotides. A Wang, Jing-Houng Wang Antisense & nucleic acid drug development 1999 new
Two functional domains of the epsilon subunit of DNA polymerase III. Fred W Perrino, Scott Harvey, S M McNeill Biochemistry 1999 pols set
The tamas gene, identified as a mutation that disrupts larval behavior in Drosophila melanogaster, codes for the mitochondrial DNA polymerase catalytic subunit (DNApol-gamma125). Balaji Iyengar, J Roote, Ana Regina Campos Genetics 1999 new
Autographa californica nuclear polyhedrosis virus DNA polymerase: measurements of processivity and strand displacement. V V McDougal, L A Guarino Journal of virology 1999 partial results
DNA polymerase beta-like nucleotidyltransferase superfamily: identification of three new families, classification and evolutionary history. L Aravind, Eugene V Koonin Nucleic acids research 1999 new
Resolution of head-on collisions between the transcription machinery and bacteriophage phi29 DNA polymerase is dependent on RNA polymerase translocation. M Elías-Arnanz, Margarita Salas The EMBO journal 1999 pols set
Herpes simplex virus processivity factor UL42 imparts increased DNA-binding specificity to the viral DNA polymerase and decreased dissociation from primer-template without reducing the elongation rate. Klaus Weisshart, C S Chow, Donald M Coen Journal of virology 1999 new
Dual mode of interaction of DNA polymerase epsilon with proliferating cell nuclear antigen in primer binding and DNA synthesis. Giovanni Maga, Z O Jónsson, M Stucki, Silvio Spadari, Ulrich Hübscher Journal of molecular biology 1999 new
Intramolecular chimeras of the p51 subunit between HIV-1 and FIV reverse transcriptases suggest a stabilizing function for the p66 subunit in the heterodimeric enzyme. Taurai Tasara, Mario Amacker, Ulrich Hübscher Biochemistry 1999 pols set
Analysis of amino insertion mutations in the fingers subdomain of HIV-1 reverse transcriptase. Paul L Boyer, J Lisziewicz, F Lori, Stephen H Hughes Journal of molecular biology 1999 pols set
The kinetoplast structure-specific endonuclease I is related to the 5' exo/endonuclease domain of bacterial DNA polymerase I and colocalizes with the kinetoplast topoisomerase II and DNA polymerase beta during replication. M L Engel, D S Ray Proceedings of the National Academy of Sciences of the United States of America 1999 new
Baculovirus expression reconstitutes Drosophila mitochondrial DNA polymerase. Yazhen Wang, Laurie S Kaguni The Journal of biological chemistry 1999 new
The C-terminal region of Schizosaccaromyces pombe proliferating cell nuclear antigen is essential for DNA polymerase activity. Zvi Kelman, S Zuo, M P Arroyo, Teresa S-F Wang, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1999 new
Division of labor--sequential ATP hydrolysis drives assembly of a DNA polymerase sliding clamp around DNA. Manju M Hingorani, Linda B Bloom, Myron F Goodman, Mike E O'Donnell The EMBO journal 1999 new
Isolation and characterisation of the cDNA encoding a glycosylated accessory protein of pea chloroplast DNA polymerase. A Gaikwad, K K Tewari, Dinesh Kumar, W Chen, Sunil K Mukherjee Nucleic acids research 1999 new
Perspectives for the treatment of hepatitis B virus infections. Erik De Clercq International journal of antimicrobial agents 1999 pols set
Reverse transcriptase inhibitors can selectively block the synthesis of differently sized viral DNA transcripts in cells acutely infected with human immunodeficiency virus type 1. Yudong Quan, Liwei Rong, Chen Liang, Mark A. Wainberg Journal of virology 1999 pols set
Activity of non-nucleoside reverse transcriptase inhibitors against HIV-2 and SIV. Myriam Witvrouw, Christophe Pannecouque, Kristel Van Laethem, J Desmyter, Erik De Clercq, Anne-Mieke Vandamme AIDS (London, England) 1999 pols set
A full-length cDNA of hREV3 is predicted to encode DNA polymerase zeta for damage-induced mutagenesis in humans. W Lin, Xiaoming Wu, Zhengqiang Wang Mutation research 1999 new
bis-5-Alkylresorcinols from Panopsis rubescens that inhibit DNA polymerase beta. Jing-Zhen Deng, Shelley R Starck, Sidney M Hecht J Nat Prod 1999 new
Optical mapping of DNA polymerase I action and products. X Hu, C Aston, D C Schwartz Biochem Biophys Res Commun 1999 new
Synthesis and anti-HIV activity of 1,1,3-trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazines (TTDs): a new family of HIV-1 specific non-nucleoside reverse transcriptase inhibitors. M E Arranz, J A Díaz, S T Ingate, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, S Vega Bioorganic & medicinal chemistry 1999 pols set
Sensitivity and resistance to (+)-calanolide A of wild-type and mutated forms of HIV-1 reverse transcriptase. Yudong Quan, Dimitrios Motakis, R Buckheit, Z Q Xu, M T Flavin, Michael A. Parniak, Mark A. Wainberg Antiviral therapy 1999 pols set
Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity. Chikahide Masutani, M Araki, Ayumi Yamada, Rika Kusumoto, T Nogimori, T Maekawa, Shigenori Iwai, Fumio Hanaoka The EMBO journal 1999 new
Mutations conferring resistance to zidovudine diminish the antiviral effect of stavudine plus didanosine. J Izopet, A Bicart-See, C Pasquier, K Sandres, E Bonnet, B Marchou, J Puel, P Massip J Med Virol 1999 topics set
9-(2-Phosphonylmethoxyethyl)adenine induces tumor cell differentiation or cell death by blocking cell cycle progression through the S phase. Sigrid Hatse, Dominique Schols, Erik De Clercq, Jan Balzarini Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1999 new
Suppression of resistance to drugs targeted to human immunodeficiency virus reverse transcriptase by combination therapy. Jan Balzarini Biochemical pharmacology 1999 pols set
Two family B DNA polymerases from Aeropyrum pernix, an aerobic hyperthermophilic crenarchaeote. Isaac K O Cann, Sonoko Ishino, N Nomura, Y Sako, Yoshizumi Ishino J Bacteriol 1999 new
Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA polymerase and a polymerase editing complex. Yousif Shamoo, Thomas A Steitz Cell 1999 new
Role of antimetabolites of purine and pyrimidine nucleotide metabolism in tumor cell differentiation. Sigrid Hatse, Erik De Clercq, Jan Balzarini Biochemical pharmacology 1999 new
Determinants of nucleotide sugar recognition in an archaeon DNA polymerase. Andrew F Gardner, William E Jack Nucleic acids research 1999 pols set
Potential multifunctional inhibitors of HIV-1 reverse transcriptase. Novel [AZT]-[TSAO-T] and [d4T]-[TSAO-T] heterodimers modified in the linker and in the dideoxynucleoside region. Sonsoles Velázquez, V Tuñón, M L Jimeno, Cristina Chamorro, Erik De Clercq, Jan Balzarini, María-José Camarasa Journal of medicinal chemistry 1999 pols set
Characterisation of XlCdc1, a Xenopus homologue of the small (PolD2) subunit of DNA polymerase delta; identification of ten conserved regions I-X based on protein sequence comparisons across ten eukaryotic species. N Reynolds, Stuart A MacNeill Gene 1999 new
The carboxyl terminus of the bacteriophage T4 DNA polymerase contacts its sliding clamp at the subunit interface. S C Alley, A D Jones, P Soumillion, Stephen J Benkovic The Journal of biological chemistry 1999 pols set
Modulation of drug resistance mediated by loss of mismatch repair by the DNA polymerase inhibitor aphidicolin. N J Moreland, M Illand, Y T Kim, J Paul, R Brown Cancer research 1999 new
The Tyr-265-to-Cys mutator mutant of DNA polymerase beta induces a mutator phenotype in mouse LN12 cells. C A Clairmont, L Narayanan, Ka-Wai Sun, Peter M Glazer, Joann B Sweasy Proceedings of the National Academy of Sciences of the United States of America 1999 pols set
Surface plasmon resonance measurements reveal stable complex formation between p53 and DNA polymerase alpha. C Kühn, F Müller, Christian Melle, Heinz Peter Nasheuer, F Janus, W Deppert, Frank Grosse Oncogene 1999 new
Association of acetylcholine receptor alpha-subunit gene expression in mixed thymoma with myasthenia gravis. A Wilisch, S Gutsche, V Hoffacker, A Schultz, S Tzartos, W Nix, B Schalke, C Schneider, H K Müller-Hermelink, Andreas Marx Neurology 1999 new
Aging and DNA polymerase alpha: modulation by dietary restriction. Vinod K Srivastava, S D Miller, David L Busbee J Nutr Health Aging 1999 new
Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily. Valerie L Gerlach, L Aravind, G Gotway, R A Schultz, Eugene V Koonin, Errol C Friedberg Proceedings of the National Academy of Sciences of the United States of America 1999 topics set
Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design. Y Goldgur, R Craigie, G H Cohen, Tsuyoshi Fujiwara, T Yoshinaga, T Fujishita, H Sugimoto, T Endo, H Murai, D R Davies Proceedings of the National Academy of Sciences of the United States of America 1999 new
The enzymological basis for resistance of herpesvirus DNA polymerase mutants to acyclovir: relationship to the structure of alpha-like DNA polymerases. L Huang, K K Ishii, H Zuccola, A M Gehring, Charles B C Hwang, J Hogle, Donald M Coen Proceedings of the National Academy of Sciences of the United States of America 1999 new
The internal workings of a DNA polymerase clamp-loading machine. J Turner, Manju M Hingorani, Zvi Kelman, Mike E O'Donnell The EMBO journal 1999 new
Dna2 mutants reveal interactions with Dna polymerase alpha and Ctf4, a Pol alpha accessory factor, and show that full Dna2 helicase activity is not essential for growth. T Formosa, T Nittis Genetics 1999 new
DNA polymerase mutagenic bypass and proofreading of endogenous DNA lesions. Kristin A Eckert, Patricia L Opresko Mutation research 1999 new
Purification of Autographa californica nucleopolyhedrovirus DNA polymerase from infected insect cells. X Hang, L A Guarino The Journal of general virology 1999 new
Isolation and identification of the third subunit of mammalian DNA polymerase delta by PCNA-affinity chromatography of mouse FM3A cell extracts. Patrick Hughes, I Tratner, M Ducoux, K Piard, Giuseppe Baldacci Nucleic acids research 1999 pols set
Primary structure of the DNA polymerase I gene of an alpha-proteobacterium, Rhizobium leguminosarum, and comparison with other family A DNA polymerases. Y P Huang, J A Downie, J Ito Curr Microbiol 1999 new
Structural elucidation of the binding and inhibitory properties of lanthanide (III) ions at the 3'-5' exonucleolytic active site of the Klenow fragment. C A Brautigam, K Aschheim, Thomas A Steitz Chemistry & biology 1999 complete
Cell cycle-dependent regulation of human DNA polymerase alpha-primase activity by phosphorylation. C Voitenleitner, Christoph Rehfuess, M Hilmes, L O'Rear, P C Liao, D A Gage, Robert Ott, Heinz Peter Nasheuer, Ellen Fanning Molecular and cellular biology 1999 pols set
A single tyrosine prevents insertion of ribonucleotides in the eukaryotic-type phi29 DNA polymerase. Ana Bonnin, José María Lázaro, Luis Blanco, Margarita Salas Journal of molecular biology 1999 pols set
Molecular architecture of the mouse DNA polymerase alpha-primase complex. Takeshi Mizuno, K Yamagishi, Hiroshi Miyazawa, Fumio Hanaoka Molecular and cellular biology 1999 complete Takeshi Mizuno*
The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta. Chikahide Masutani, Rika Kusumoto, Ayumi Yamada, N Dohmae, Masayuki Yokoi, M Yuasa, M Araki, Shigenori Iwai, K Takio, Fumio Hanaoka Nature 1999 topics set
Detection of mutations in the DNA polymerase delta gene of human sporadic colorectal cancers and colon cancer cell lines. T Flohr, J C Dai, J Büttner, O Popanda, E Hagmüller, H W Thielmann Int J Cancer 1999 new
A new point mutation (P157S) in the reverse transcriptase of human immunodeficiency virus type 1 confers low-level resistance to (-)-beta-2',3'-dideoxy-3'-thiacytidine. R A Smith, George J Klarmann, K M Stray, U K von Schwedler, Raymond F Schinazi, Bradley D Preston, Thomas W North Antimicrobial agents and chemotherapy 1999 pols set
Role of the "YxGG/A" motif of Phi29 DNA polymerase in protein-primed replication. Verónica Truniger, Luis Blanco, Margarita Salas Journal of molecular biology 1999 pols set
Touching the heart of HIV-1 drug resistance: the fingers close down on the dNTP at the polymerase active site. Stefan G Sarafianos, Kalyan Das, Jianping Ding, Paul L Boyer, Stephen H Hughes, Edward Arnold Chemistry & biology 1999 topics set
Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase. A Pellicioli, C Lucca, G Liberi, Federica Marini, M Lopes, Paolo Plevani, A Romano, P P Di Fiore, Marco Foiani The EMBO journal 1999 new
Processive proofreading and the spatial relationship between polymerase and exonuclease active sites of bacteriophage phi29 DNA polymerase. Miguel de Vega, Luis Blanco, Margarita Salas Journal of molecular biology 1999 partial results
The cyanogenic glucoside, prunasin (D-mandelonitrile-beta-D-glucoside), is a novel inhibitor of DNA polymerase beta. Yoshiyuki Mizushina, N Takahashi, Akitsu Ogawa, K Tsurugaya, Hiroyuki Koshino, Masaharu Takemura, Shonen Yoshida, Akio Matsukage, Fumio Sugawara, Kengo Sakaguchi J Biochem 1999 new
Repetitive use of a phosphate-binding module in DNA polymerase beta, Oct-1 POU domain and phage repressors. K Yura, M Shionyu, K Kawatani, M Go Cell Mol Life Sci 1999 new
Design of MKC-442 (emivirine) analogues with improved activity against drug-resistant HIV mutants. Andrew L Hopkins, Jingshan Ren, Hiromichi Tanaka, Masanori Baba, M Okamato, David I Stuart, David K Stammers J Med Chem 1999 topics set
Current pharmacological approaches to the therapy of varicella zoster virus infections: a guide to treatment. Robert Snoeck, Graciella Andrei, Erik De Clercq Drugs 1999 new
Interaction of DNA polymerase I (Klenow fragment) with DNA substrates containing extrahelical bases: implications for proofreading of frameshift errors during DNA synthesis. Wai-Chung Lam, Edwin J C Van der Schans, L C Sowers, David P Millar Biochemistry 1999 pols set
In vitro selection and characterization of HIV-1 with reduced susceptibility to PMPA. Mark A. Wainberg, Michael D Miller, Yudong Quan, H Salomon, A S Mulato, P D Lamy, Nicolas A Margot, K E Anton, J M Cherrington Antivir Ther 1999 topics set
Human papillomavirus DNA replication. Interactions between the viral E1 protein and two subunits of human dna polymerase alpha/primase. K L Conger, Jen-Sing Liu, Shu-Ru Kuo, L T Chow, Teresa S-F Wang The Journal of biological chemistry 1999 pols set
Polymerase blockage and misincorporation of dNTPs opposite the ethylene dibromide-derived DNA adducts S-[2-(N7-guanyl)ethyl]glutathione, S-[2-(N2-guanyl)ethyl]glutathione, and S-[2-(O6-guanyl)ethyl]glutathione. M S Kim, F Peter Guengerich Chemical research in toxicology 1998 new
Comparison of two methods of staining apoptotic cells of leukemia cell lines. Terminal deoxynucleotidyl transferase and DNA polymerase I reactions. I Yamadori, T Yoshino, E Kondo, L Cao, T Akagi, Y Matsuo, J Minowada J Histochem Cytochem 1998 new
The biochemical inhibition mode of bredinin-5'-monophosphate on DNA polymerase beta. Yoshiyuki Mizushina, Akio Matsukage, Kengo Sakaguchi Biochimica et biophysica acta 1998 pols set
Human DNA polymerase beta deoxyribose phosphate lyase. Substrate specificity and catalytic mechanism. Rajendra Prasad, William A Beard, Phyllis R Strauss, Samuel H Wilson The Journal of biological chemistry 1998 pols set
Klenow fragment and DNA polymerase alpha-primase fromserva calf thymus in water-in-oil microemulsions. Rashid O Anarbaev, I B Elepov, Olga I Lavrik Biochimica et biophysica acta 1998 new
Transition between different binding modes in rat DNA polymerase beta-ssDNA complexes. Maria J Jezewska, Surendran Rajendran, Wlodzimierz Bujalowski Journal of molecular biology 1998 new
DNA polymerase beta: effects of gapped DNA substrates on dNTP specificity, fidelity, processivity and conformational changes. J Ahn, V S Kraynov, Xuejun Zhong, B G Werneburg, Ming-Daw Tsai Biochem J 1998 new
DNA polymerase template switching at specific sites on the phi29 genome causes the in vivo accumulation of subgenomic phi29 DNA molecules. V Murthy, Wilfried J J Meijer, Luis Blanco, Margarita Salas Molecular microbiology 1998 pols set
Immunohistochemical detection of human mtDNA polymerase gamma and of human mitochondrial transcription factor A in cytochrome-c-oxidase-deficient oxyphil cells of hyperfunctional parathyroids. J Müller-Höcker, S Schäfer, William C Copeland, R Wiesner, P Seibel Virchows Archiv : an international journal of pathology 1998 new
Functional analysis of amino acid residues constituting the dNTP binding pocket of HIV-1 reverse transcriptase. D Harris, Neerja Kaushik, P K Pandey, P N Yadav, V N Pandey The Journal of biological chemistry 1998 pols set
Synthetic nucleosides and nucleotides. 40. Selective inhibition of eukaryotic DNA polymerase alpha by 9-(beta-D-arabinofuranosyl)-2-(p-n-butylanilino) adenine 5'-triphosphate (BuAaraATP) and its 2'-up azido analog: synthesis and enzymatic evaluations. A Tomikawa, M Seno, K Sato-Kiyotaki, C Ohtsuki, T Hirai, Tsuyoshi Yamaguchi, T Kawaguchi, Shonen Yoshida, Mineo Saneyoshi Nucleosides Nucleotides 1998 topics set
Stoichiometry and mechanism of assembly of SV40 T antigen complexes with the viral origin of DNA replication and DNA polymerase alpha-primase. S G Huang, Klaus Weisshart, I Gilbert, Ellen Fanning Biochemistry 1998 pols set
ND10 protein PML is recruited to herpes simplex virus type 1 prereplicative sites and replication compartments in the presence of viral DNA polymerase. J Burkham, Donald M Coen, Sandra K Weller J Virol 1998 new
Bacteriophage phi29 early protein p17 is conditionally required for the first rounds of viral DNA replication. P Crucitti, José María Lázaro, V Benes, Margarita Salas Gene 1998 pols set
The structure of HIV-1 reverse transcriptase complexed with an RNA pseudoknot inhibitor. Joachim Jaeger, Tobias Restle, Thomas A Steitz The EMBO journal 1998 topics set
Destabilized PCNA trimers suppress defective Rfc1 proteins in vivo and in vitro. WH Beckwith, Q Sun, R Bosso, K J Gerik, Peter M J Burgers, MA McAlear Biochemistry 1998 new
Efficient translesion replication in the absence of Escherichia coli Umu proteins and 3'-5' exonuclease proofreading function. Dominique Vandewiele, Angela Borden, Paul I O'Grady, Roger Woodgate, Christopher W Lawrence Proceedings of the National Academy of Sciences of the United States of America 1998 new
Recombinant His-tagged DNA polymerase. II. Cloning and purification of Thermus aquaticus recombinant DNA polymerase (Stoffel fragment). S Dabrowski, J Kur Acta Biochim Pol 1998 new
Impaired mismatch extension by a herpes simplex DNA polymerase mutant with an editing nuclease defect. R O Baker, J D Hall The Journal of biological chemistry 1998 new
Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. James R Kiefer, C Mao, J C Braman, Lorena S Beese Nature 1998 partial results
Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism. Peter R Meyer, Suzanne E Matsuura, Antero G So, Walter A Scott Proceedings of the National Academy of Sciences of the United States of America 1998 topics set
The herpes simplex virus type 1 helicase-primase. Analysis of helicase activity. M Falkenberg, P Elias, I. Robert Lehman The Journal of biological chemistry 1998 pols set
Effect of accessory proteins on T4 DNA polymerase replication fidelity. L C Kroutil, M W Frey, B F Kaboord, Thomas A Kunkel, Stephen J Benkovic Journal of molecular biology 1998 partial results
The Pol beta-14 dominant negative rat DNA polymerase beta mutator mutant commits errors during the gap-filling step of base excision repair in Saccharomyces cerevisiae. C A Clairmont, Joann B Sweasy J Bacteriol 1998 new
Mismatched nucleotides may facilitate expansion of trinucleotide repeats in genetic diseases. M Nakayabu, S Miwa, Motoshi Suzuki, Shunji Izuta, G Sobue, Shonen Yoshida Nucleic acids research 1998 pols set
Inducible expression of IkappaBalpha repressor mutants interferes with NF-kappaB activity and HIV-1 replication in Jurkat T cells. H Kwon, N Pelletier, C DeLuca, P Genin, S Cisternas, R Lin, Mark A. Wainberg, J Hiscott The Journal of biological chemistry 1998 pols set
Efficacy and tolerability of stavudine plus lamivudine in treatment-naive and treatment-experienced patients with HIV-1 infection. C Katlama, M A Valantin, S Matheron, A Coutellier, V Calvez, D Descamps, C Longuet, M Bonmarchand, R Tubiana, M De Sa, R Lancar, Henri Agut, F Brun-Vezinet, D Costagliola Ann Intern Med 1998 new
Steady-state and pre-steady-state kinetic analysis of 8-oxo-7,8-dihydroguanosine triphosphate incorporation and extension by replicative and repair DNA polymerases. H J Einolf, N Schnetz-Boutaud, F Peter Guengerich Biochemistry 1998 pols set
Prereplicative increase of nuclear matrix-bound DNA polymerase-alpha and primase activities in HeLa S3 cells following dilution of long-term cultures. A M Martelli, S Capitani, L M Neri J Cell Biochem 1998 new
The 41-kDa protein of human herpesvirus 6 specifically binds to viral DNA polymerase and greatly increases DNA synthesis. K Lin, Robert P Ricciardi Virology 1998 new
Similarities to a LINE element shared by Anopheline and Culicine mosquitos map to the distal end of dihydrofolate reductase amplicons in Aedes albopictus mosquito cells. Zhan-hui Wang, A M Fallon Insect biochemistry and molecular biology 1998 new
Crystal structures of the Klenow fragment of Thermus aquaticus DNA polymerase I complexed with deoxyribonucleoside triphosphates. Yingqian Li, Y Kong, S Korolev, Gabriel Waksman Protein science : a publication of the Protein Society 1998 topics set
A herpes simplex virus DNA polymerase mutation that specifically attenuates neurovirulence in mice. E Pelosi, F Rozenberg, Donald M Coen, K L Tyler Virology 1998 new
Thermostable DNA-polymerase from Thermus thermophilus B35: isolation and characterization of some properties. Nadejda I Rechkunova, A G Akishev, Natalia A Lebedeva, Svetlana N Khodyreva, S Kh Degtyarev, Olga I Lavrik Biochemistry (Mosc) 1998 new
Human DNA polymerase beta recognizes single-stranded DNA using two different binding modes. Surendran Rajendran, Maria J Jezewska, Wlodzimierz Bujalowski The Journal of biological chemistry 1998 pols set
phi29 DNA polymerase residue Ser122, a single-stranded DNA ligand for 3'-5' exonucleolysis, is required to interact with the terminal protein. Miguel de Vega, Luis Blanco, Margarita Salas The Journal of biological chemistry 1998 pols set
Formation of a DNA loop at the replication fork generated by bacteriophage T7 replication proteins. K Park, Zeger Debyser, Stanley Tabor, Charles C Richardson, Jack D Griffith The Journal of biological chemistry 1998 pols set
The mechanism of action of T7 DNA polymerase. Sylvie Doublié, Tom Ellenberger Current opinion in structural biology 1998 pols set
A mutation at position 190 of human immunodeficiency virus type 1 reverse transcriptase interacts with mutations at positions 74 and 75 via the template primer. Paul L Boyer, Hong Qiang Gao, Stephen H Hughes Antimicrobial agents and chemotherapy 1998 pols set
Recombinant His-tagged DNA polymerase. I. Cloning, purification and partial characterization of Thermus thermophilus recombinant DNA polymerase. S Dabrowski, J Kur Acta Biochim Pol 1998 pols set
DNA polymerase III of Gram-positive eubacteria is a zinc metalloprotein conserving an essential finger-like domain. Marjorie H Barnes, C J Leo, Neal C Brown Biochemistry 1998 new
Frequency of MAGE-3 gene expression in HLA-A2 positive patients with non-small cell lung cancer. K Gotoh, Yasushi Yatabe, T Sugiura, K Takagi, M Ogawa, T Takahashi, T Takahashi, T Mitsudomi Lung cancer (Amsterdam, Netherlands) 1998 new
Inhibition of HIV-1 replication by a Tat RNA-binding domain peptide analog. I Choudhury, Jianhong Wang, A B Rabson, S Stein, S Pooyan, S Stein, M J Leibowitz Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1998 pols set
NTP concentration effects on initial transcription by T7 RNAP indicate that translocation occurs through passive sliding and reveal that divergent promoters have distinct NTP concentration requirements for productive initiation. R Guajardo, P Lopez, M Dreyfus, R Sousa Journal of molecular biology 1998 new
Altered drug sensitivity, fitness, and evolution of human immunodeficiency virus type 1 with pol gene mutations conferring multi-dideoxynucleoside resistance. Y Maeda, D J Venzon, Hiroyuki Mitsuya J Infect Dis 1998 new
Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase Cdk. S Mimura, H Takisawa The EMBO journal 1998 new
Exonuclease-polymerase active site partitioning of primer-template DNA strands and equilibrium Mg2+ binding properties of bacteriophage T4 DNA polymerase. J M Beechem, M R Otto, Linda B Bloom, R Eritja, Linda J Reha-Krantz, Myron F Goodman Biochemistry 1998 complete
Replication factor C disengages from proliferating cell nuclear antigen (PCNA) upon sliding clamp formation, and PCNA itself tethers DNA polymerase delta to DNA. Vladimir N Podust, N Tiwari, S Stephan, Ellen Fanning The Journal of biological chemistry 1998 new
Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase. Dominique Arion, Neerja Kaushik, Suzanne McCormick, G Borkow, Michael A. Parniak Biochemistry 1998 topics set
Dynamic regulation of gastric autoimmunity by thyroid hormone. Jide Wang, N D Griggs, K S Tung, J R Klein International immunology 1998 new
Adenovirus DNA polymerase: domain organisation and interaction with preterminal protein. E J Parker, C H Botting, A Webster, R T Hay Nucleic acids research 1998 new
Eukaryotic DNA polymerases in DNA replication and DNA repair. Peter M J Burgers Chromosoma 1998 new
Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives. Jingshan Ren, R M Esnouf, Andrew L Hopkins, J Warren, Jan Balzarini, David I Stuart, David K Stammers Biochemistry 1998 topics set
Polymerase recognition of synthetic oligodeoxyribonucleotides incorporating degenerate pyrimidine and purine bases. F Hill, David Loakes, D M Brown Proceedings of the National Academy of Sciences of the United States of America 1998 pols set
The mutator form of polymerase beta with amino acid substitution at tyrosine 265 in the hinge region displays an increase in both base substitution and frame shift errors. Patricia L Opresko, Joann B Sweasy, Kristin A Eckert Biochemistry 1998 new
Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites. Robert E Johnson, Carlos A Torres-Ramos, Tadahide Izumi, Sankar Mitra, Satya Prakash, Louise Prakash Genes & development 1998 new
The second-largest subunit of the mouse DNA polymerase alpha-primase complex facilitates both production and nuclear translocation of the catalytic subunit of DNA polymerase alpha. Takeshi Mizuno, Nobutoshi Ito, Masayuki Yokoi, Atsushi Kobayashi, Katsuyuki Tamai, Hiroshi Miyazawa, Fumio Hanaoka Molecular and cellular biology 1998 complete Takeshi Mizuno*
ATP hydrolysis catalyzed by human replication factor C requires participation of multiple subunits. J Cai, N Yao, E Gibbs, Jeff Finkelstein, B Phillips, Mike E O'Donnell, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1998 new
Substitution of Asn for Ser543 in the large fragment of Taq DNA polymerase increases the efficiency of synthesis of long DNA molecules. K B Ignatov, A I Miroshnikov, V M Kramarov FEBS letters 1998 pols set
Alternative conformations of human replication protein A are detected by crosslinks with primers carrying a photoreactive group at the 3'-end. Olga I Lavrik, Dmitry M Kolpashchikov, Heinz Peter Nasheuer, Klaus Weisshart, Alain Favre FEBS letters 1998 new
A new look at old mutants of T4 DNA polymerase. Nancy G Nossal Genetics 1998 complete
Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution. Sylvie Doublié, Stanley Tabor, A M Long, Charles C Richardson, Tom Ellenberger Nature 1998 topics set
Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs. Yvan Canitrot, Christophe Cazaux, Mathilde Fréchet, K Bouayadi, C Lesca, B Salles, Jean-Sébastien Hoffmann Proceedings of the National Academy of Sciences of the United States of America 1998 new
Chimeric HIV-1 and feline immunodeficiency virus reverse transcriptases: critical role of the p51 subunit in the structural integrity of heterodimeric lentiviral DNA polymerases. Mario Amacker, Ulrich Hübscher Journal of molecular biology 1998 pols set
Resistance of human nucleotide excision repair synthesis in vitro to p21Cdn1. M K Shivji, Elena Ferrari, K Ball, Ulrich Hübscher, Richard D Wood Oncogene 1998 new
Characterization of the two small subunits of Saccharomyces cerevisiae DNA polymerase delta. K J Gerik, Xincang Li, A Pautz, Peter M J Burgers The Journal of biological chemistry 1998 pols set
Regulation of DNA replication and repair proteins through interaction with the front side of proliferating cell nuclear antigen. Z O Jónsson, R Hindges, Ulrich Hübscher The EMBO journal 1998 new
The solution structure of functionally active human proliferating cell nuclear antigen determined by small-angle neutron scattering. P Schurtenberger, S U Egelhaaf, R Hindges, Giovanni Maga, Z O Jónsson, R P May, O Glatter, Ulrich Hübscher Journal of molecular biology 1998 new
Newly synthesized L-enantiomers of 3'-fluoro-modified beta-2'-deoxyribonucleoside 5'-triphosphates inhibit hepatitis B DNA polymerases but not the five cellular DNA polymerases alpha, beta, gamma, delta, and epsilon nor HIV-1 reverse transcriptase. M von Janta-Lipinski, B Costisella, H Ochs, Ulrich Hübscher, P Hafkemeyer, E Matthes Journal of medicinal chemistry 1998 pols set
DNA ligase I selectively affects DNA synthesis by DNA polymerases delta and epsilon suggesting differential functions in DNA replication and repair. R Mossi, Elena Ferrari, Ulrich Hübscher The Journal of biological chemistry 1998 new
DNA secondary structure effects on DNA synthesis catalyzed by HIV-1 reverse transcriptase. Zucai Suo, Kenneth A Johnson The Journal of biological chemistry 1998 new
The spectrum of acridine resistant mutants of bacteriophage T4 reveals cryptic effects of the tsL141 DNA polymerase allele on spontaneous mutagenesis. F J Wang, L S Ripley Genetics 1998 partial results
Dissecting the order of bacteriophage T4 DNA polymerase holoenzyme assembly. D J Sexton, B F Kaboord, Anthony J Berdis, T E Carver, Stephen J Benkovic Biochemistry 1998 topics set
Unusual insertion element polymorphisms in the promoter and terminator regions of the mucAB-like genes of R471a and R446b. O I Kulaeva, Eugene V Koonin, J C Wootton, A S Levine, Roger Woodgate Mutation research 1998 new
Devoted to the lagging strand-the subunit of DNA polymerase III holoenzyme contacts SSB to promote processive elongation and sliding clamp assembly. Zvi Kelman, Alexander Yuzhakov, J Andjelkovic, Mike E O'Donnell The EMBO journal 1998 pols set
Non-homologous recombination mediated by Thermus aquaticus DNA polymerase I. Evidence supporting a copy choice mechanism. P G Zaphiropoulos Nucleic acids research 1998 pols set
Uracil glycol deoxynucleoside triphosphate is a better substrate for DNA polymerase I Klenow fragment than thymine glycol deoxynucleoside triphosphate. A A Purmal, J P Bond, B A Lyons, Y W Kow, Susan S Wallace Biochemistry 1998 pols set
Impairment of proliferating cell nuclear antigen-dependent apurinic/apyrimidinic site repair on linear DNA. S Biade, Robert W Sobol, Samuel H Wilson, Yoshihiro Matsumoto The Journal of biological chemistry 1998 new
New perspectives for the treatment of HIV infections. Erik De Clercq Verhandelingen - Koninklijke Academie voor Geneeskunde van België 1998 pols set
A heterodimeric DNA polymerase: evidence that members of Euryarchaeota possess a distinct DNA polymerase. Isaac K O Cann, Kayoko Komori, H Toh, S Kanai, Yoshizumi Ishino Proceedings of the National Academy of Sciences of the United States of America 1998 new
Comparison of the LiPA HIV-1 RT test, selective PCR and direct solid phase sequencing for the detection of HIV-1 drug resistance mutations. J C Schmit, L Ruiz, L Stuyver, Kristel Van Laethem, I Vanderlinden, T Puig, R Rossau, J Desmyter, Erik De Clercq, B Clotet, A-M Vandamme Journal of virological methods 1998 pols set
Purification and characterization of a 100 kDa DNA polymerase from cauliflower inflorescence. H Seto, Masami Hatanaka, Seisuke Kimura, Masahiko Oshige, Y Tsuya, Yoshiyuki Mizushina, Tomoyuki Sawado, N Aoyagi, Takehisa Matsumoto, Junji Hashimoto, Kengo Sakaguchi Biochem J 1998 new
Physicochemical and biochemical properties of 2',5'-linked RNA and 2',5'-RNA:3',5'-RNA "hybrid" duplexes. M Wasner, Dominique Arion, G Borkow, A Noronha, A H Uddin, Michael A. Parniak, Masad J Damha Biochemistry 1998 pols set
Phase I study of atevirdine mesylate (U-87201E) monotherapy in HIV-1-infected patients. L M Demeter, P M Meehan, G Morse, M A Fischl, M Para, W Powderly, J Leedom, J Holden-Wiltse, C Greisberger, K Wood, J Timpone, L K Wathen, T Nevin, L Resnick, D H Batts, R C Reichman Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1998 pols set
Escherichia coli RNA and DNA polymerase bypass of dihydrouracil: mutagenic potential via transcription and replication. J Liu, P W Doetsch Nucleic acids research 1998 new
Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation. Yingqian Li, S Korolev, Gabriel Waksman The EMBO journal 1998 topics set
The RGD sequence in phage phi29 terminal protein is required for interaction with phi29 DNA polymerase. B Illana, A Zaballos, Luis Blanco, Margarita Salas Virology 1998 pols set
The small subunits of human and mouse DNA polymerase epsilon are homologous to the second largest subunit of the yeast Saccharomyces cerevisiae DNA polymerase epsilon. Maarit Jokela, M Mäkiniemi, S Lehtonen, C Szpirer, U Hellman, Juhani E Syväoja Nucleic acids research 1998 pols set
The second subunit of DNA polymerase III (delta) is encoded by the HYS2 gene in Saccharomyces cerevisiae. Keiji Hashimoto, Naomi Nakashima, T Ohara, Satoko Maki, Akio Sugino Nucleic acids research 1998 pols set
Processivity of DNA polymerases: two mechanisms, one goal. Zvi Kelman, Jerard Hurwitz, Mike E O'Donnell Structure (London, England : 1993) 1998 new
Creation of genetic information by DNA polymerase of the archaeon Thermococcus litoralis: influences of temperature and ionic strength. Norio Ogata, T Miura Nucleic acids research 1998 new
Identification and characterization of two DNA polymerase activities present in Trypanosoma brucei mitochondria. J Fuenmayor, J Zhang, W Ruyechan, N Williams J Eukaryot Microbiol 1998 new
Incorporation and excision of 9-(2-phosphonylmethoxyethyl)guanine (PMEG) by DNA polymerase delta and epsilon in vitro. P Kramata, Kathleen M Downey, L R Paborsky The Journal of biological chemistry 1998 new
The inhibitory effect of novel triterpenoid compounds, fomitellic acids, on DNA polymerase beta. Yoshiyuki Mizushina, Naotaka Tanaka, A Kitamura, Katsuyuki Tamai, M Ikeda, Masaharu Takemura, Fumio Sugawara, Takao Arai, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi Biochem J 1998 pols set
High-temperature, nonradioactive primer extension assay for determination of a transcription-initiation site. Masami Yamada, H Izu, T Nitta, K Kurihara, T Sakurai BioTechniques 1998 topics set
RNA-polymerase, DNA-polymerase, DNA-methyltransferase and sphingomyelinase activities in liver nuclei of rats of different Age. E B Romanenko, Z N Demidenko, B F Vanyushin Biochemistry (Mosc) 1998 new
How E. coli DNA polymerase I (Klenow fragment) distinguishes between deoxy- and dideoxynucleotides. Mekbib Astatke, Nigel D F Grindley, Catherine M Joyce Journal of molecular biology 1998 complete Katy Langhorst
Role of the first aspartate residue of the "YxDTDS" motif of phi29 DNA polymerase as a metal ligand during both TP-primed and DNA-primed DNA synthesis. J Saturno, José María Lázaro, Luis Blanco, Margarita Salas Journal of molecular biology 1998 pols set
Role of the core DNA polymerase III subunits at the replication fork. Alpha is the only subunit required for processive replication. K J Marians, H Hiasa, D R Kim, Charles S McHenry The Journal of biological chemistry 1998 new
Misincorporation of 2'-deoxyoxanosine 5'-triphosphate by DNA polymerases and its implication for mutagenesis. Toshinori Suzuki, Masaru Yoshida, Masami Yamada, Hiroshi Ide, M Kobayashi, K Kanaori, K Tajima, K Makino Biochemistry 1998 topics set
Crystal structure of Taq DNA polymerase in complex with an inhibitory Fab: the Fab is directed against an intermediate in the helix-coil dynamics of the enzyme. R Murali, D J Sharkey, J L Daiss, H M Murthy Proceedings of the National Academy of Sciences of the United States of America 1998 topics set
Abasic analogues of TSAO-T as the first sugar derivatives that specifically inhibit HIV-1 reverse transcriptase. Sonsoles Velázquez, Cristina Chamorro, María-Jesús Pérez-Pérez, R Alvarez, M L Jimeno, A Martín-Domenech, C Pérez, Federico Gago, Erik De Clercq, Jan Balzarini, Ana San-Félix, María-José Camarasa Journal of medicinal chemistry 1998 pols set
An approach towards the synthesis of potential metal-chelating TSAO-T derivatives as bidentate inhibitors of human immunodeficiency virus type 1 reverse transcriptase. Cristina Chamorro, María-José Camarasa, María-Jesús Pérez-Pérez, Erik De Clercq, Jan Balzarini, Ana San Félix Antiviral chemistry & chemotherapy 1998 pols set
Use of fluorescence resonance energy transfer to investigate the conformation of DNA substrates bound to the Klenow fragment. W S Furey, Catherine M Joyce, M A Osborne, D Klenerman, J A Peliska, S Balasubramanian Biochemistry 1998 pols set
Treatment of visna virus infection in lambs with the acyclic nucleoside phosphonate analogue 9-(2-phosphonylmethoxyethyl)adenine (PMEA). H Thormar, G Georgsson, E Gunnarsson, Lieve Naesens, S Torsteinsdóttir, Jan Balzarini, Erik De Clercq Antiviral chemistry & chemotherapy 1998 new
Functional association of poly(ADP-ribose) polymerase with DNA polymerase alpha-primase complex: a link between DNA strand break detection and DNA replication. F Dantzer, H P Nasheuer, J L Vonesch, Gilbert de Murcia, J Ménissier-de Murcia Nucleic acids research 1998 new
Sanger DNA-sequencing reactions performed in a solid-phase nanoreactor directly coupled to capillary gel electrophoresis. S A Soper, D C Williams, Yongli Xu, S J Lassiter, Yongqing Zhang, S M Ford, R C Bruch Analytical chemistry 1998 new
Localization of the active site of HIV-1 reverse transcriptase-associated RNase H domain on a DNA template using site-specific generated hydroxyl radicals. Matthias Götte, G Maier, H J Gross, H Heumann The Journal of biological chemistry 1998 pols set
Crystallization and preliminary X-ray diffraction studies of DNA polymerase from the thermophilic archaeon Sulfolobus solfataricus. Vassilios Nastopoulos, Francesca M Pisani, Carmelinda Savino, Luca Federici, Mosè Rossi, Demetrius Tsernoglou Acta Crystallogr D Biol Crystallogr 1998 new
The interdomain connector loop of human PCNA is involved in a direct interaction with human polymerase delta. Peiming Zhang, Younguk Sun, H Hsu, Linqi Zhang, Yongqing Zhang, Marietta Y W T Lee The Journal of biological chemistry 1998 pols set
Enzymatic processing of uracil glycol, a major oxidative product of DNA cytosine. A A Purmal, G W Lampman, J P Bond, Zafer Hatahet, Susan S Wallace The Journal of biological chemistry 1998 new
Improvement of HLA class I and class II PCR-SSP typing by using timed-release activity of DNA polymerase. D F Chen, I Seibert, H Y Chen, I Herbst-Kiene, L T Pastucha, W Stangel Tissue Antigens 1998 pols set
The proofreading pathway of bacteriophage T4 DNA polymerase. Linda J Reha-Krantz, L A Marquez, E Elisseeva, R P Baker, Linda B Bloom, H B Dunford, Myron F Goodman The Journal of biological chemistry 1998 complete
Enhanced impairment of chain elongation by inhibitors of HIV reverse transcriptase in cell-free reactions yielding longer DNA products. Yudong Quan, Chen Liang, P Inouye, Mark A. Wainberg Nucleic acids research 1998 pols set
Dominance of the E89G substitution in HIV-1 reverse transcriptase in regard to increased polymerase processivity and patterns of pausing. Yudong Quan, P Inouye, Chen Liang, Liwei Rong, Matthias Götte, Mark A. Wainberg The Journal of biological chemistry 1998 pols set
Advantages of a new Taq DNA polymerase in multiplex PCR and time-release PCR. C Kebelmann-Betzing, K Seeger, S Dragon, G Schmitt, A Möricke, T A Schild, G Henze, B Beyermann BioTechniques 1998 pols set
Fomitellic acids, triterpenoid inhibitors of eukaryotic DNA polymerases from a basidiomycete, Fomitella fraxinea. Naotaka Tanaka, A Kitamura, Yoshiyuki Mizushina, Fumio Sugawara, Kengo Sakaguchi Journal of natural products 1998 new
Mechanistic studies of early pausing events during initiation of HIV-1 reverse transcription. Chen Liang, Liwei Rong, Matthias Götte, Xincang Li, Yudong Quan, Lawrence Kleiman, Mark A. Wainberg The Journal of biological chemistry 1998 new
Studies on inhibitors of mammalian DNA polymerase alpha and beta: sulfolipids from a pteridophyte, Athyrium niponicum. Yoshiyuki Mizushina, I Watanabe, Keisuke Ohta, Masaharu Takemura, Hiroeki Sahara, N Takahashi, S Gasa, Fumio Sugawara, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi Biochemical pharmacology 1998 new
Polyamide nucleic acid-DNA chimera lacking the phosphate backbone are novel primers for polymerase reaction catalyzed by DNA polymerases. H S Misra, P K Pandey, Mukund J Modak, R Vinayak, V N Pandey Biochemistry 1998 new
Amino acid residues involved in determining the processivity of the 3'-5' exonuclease activity in a family B DNA polymerase from the thermoacidophilic archaeon Sulfolobus solfataricus. Francesca M Pisani, Mariarita De Felice, Mosè Rossi Biochemistry 1998 new
Rates of spontaneous mutation. J W Drake, B Charlesworth, D Charlesworth, J F Crow Genetics 1998 topics set
Selective inhibition of HIV-1 reverse transcriptase by an antiviral inhibitor, (R)-9-(2-Phosphonylmethoxypropyl)adenine. Zucai Suo, Kenneth A Johnson The Journal of biological chemistry 1998 pols set
Sulfated glycoglycerolipid from archaebacterium inhibits eukaryotic DNA polymerase alpha, beta and retroviral reverse transcriptase and affects methyl methanesulfonate cytotoxicity. Akitsu Ogawa, Takashi Murate, Shunji Izuta, Masaharu Takemura, Kyoji Furuta, Jun'ichi Kobayashi, T Kamikawa, Y Nimura, Shonen Yoshida Int J Cancer 1998 new
Serum DNA polymerase beta as an indicator for fatal liver injury of rat induced by D-galactosamine hydrochloride and lipopolysaccharide. O Kato, Y Fukuda, T Hayakawa, Shunji Izuta, Shonen Yoshida Biochimica et biophysica acta 1998 new
[Logical regulation of DNA polymerase mutagenesis and autonomous 3'-5'-exonuclease]. V M Krutiakov Mol Biol (Mosk) 1998 new
Loss of polymerase activity due to Tyr to Phe substitution in the YMDD motif of human immunodeficiency virus type-1 reverse transcriptase is compensated by Met to Val substitution within the same motif. D Harris, P N Yadav, V N Pandey Biochemistry 1998 pols set
[Fluorescence-based semi-automated gene scan with microsatellite markers by multiplex PCR techniques]. S Kuang, Jin Wang, W Huang, Yong Zhang, Lin Lu, Z Cheng, Li Jin Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 1998 new
Enhancement of PCR amplification yield and specificity using AmpliTaq Gold DNA polymerase. T Moretti, B Koons, B Budowle BioTechniques 1998 new
Effects of bulky polycyclic aromatic hydrocarbon adducts on DNA replication by exonuclease-deficient T7 and T4 DNA polymerases. P Keohavong, R Shukla, A Melacrinos, B W Day, Linda J Reha-Krantz DNA Cell Biol 1998 complete
DNA polymerase epsilon encoded by cdc20+ is required for chromosomal DNA replication in the fission yeast Schizosaccharomyces pombe. Akio Sugino, T Ohara, J Sebastian, Naomi Nakashima, Hiroyuki Araki Genes Cells 1998 pols set
Pressure enhances thermal stability of DNA polymerase from three thermophilic organisms. M Summit, B Scott, K Nielson, E Mathur, J Baross Extremophiles 1998 new
DNA polymerase II (epsilon) of Saccharomyces cerevisiae dissociates from the DNA template by sensing single-stranded DNA. Satoko Maki, Keiji Hashimoto, T Ohara, Akio Sugino The Journal of biological chemistry 1998 pols set
Effect of mitoxantrone on DNA polymerase of Ehrlich ascites carcinoma cells. L J Xian, H X Li, Z C Liu, Q C Pan Zhongguo Yao Li Xue Bao 1998 new
Novel 1,1,3-trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazine derivatives as non-nucleoside reverse transcriptase inhibitors that inhibit human immunodeficiency virus type 1 replication. E Arranz, J A Díaz, S T Ingate, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, S Vega Journal of medicinal chemistry 1998 new
Analysis of damage tolerance pathways in Saccharomyces cerevisiae: a requirement for Rev3 DNA polymerase in translesion synthesis. K Baynton, A Bresson-Roy, Robert P P Fuchs Molecular and cellular biology 1998 new
Multiple dideoxynucleoside analogue-resistant (MddNR) HIV-1 strains isolated from patients from different European countries. J C Schmit, Kristel Van Laethem, L Ruiz, P Hermans, S Sprecher, A Sönnerborg, M Leal, T Harrer, B Clotet, V Arendt, E Lissen, Myriam Witvrouw, J Desmyter, Erik De Clercq, A-M Vandamme AIDS (London, England) 1998 new
Aspects of the ultraviolet photobiology of some T-even bacteriophages. L A Smith, John W Drake Genetics 1998 complete
Kinetic characterization of a bacteriophage T4 antimutator DNA polymerase. P Wu, N Nossal, Stephen J Benkovic Biochemistry 1998 pols set
Crystallization and preliminary diffraction analysis of a hyperthermostable DNA polymerase from a Thermococcus archaeon. Mian Zhou, C Mao, A C Rodriguez, James R Kiefer, R B Kucera, Lorena S Beese Acta Crystallogr D Biol Crystallogr 1998 new
Efficient gap repair catalyzed in vitro by an intrinsic DNA polymerase activity of human immunodeficiency virus type 1 integrase. A Acel, B E Udashkin, Mark A. Wainberg, E A Faust J Virol 1998 new
Phi 29 DNA polymerase requires the N-terminal domain to bind terminal protein and DNA primer substrates. Verónica Truniger, José María Lázaro, Margarita Salas, Luis Blanco Journal of molecular biology 1998 pols set
Mutant DNA polymerase delta from thermosensitive Schizosaccharomyces pombe strains display reduced stimulation by proliferating cell nuclear antigen. M Perderiset, Giovanni Maga, K Piard, S Francesconi, I Tratner, Ulrich Hübscher, Giuseppe Baldacci Biochem J 1998 new
The chi psi subunits of DNA polymerase III holoenzyme bind to single-stranded DNA-binding protein (SSB) and facilitate replication of an SSB-coated template. Bradley P Glover, Charles S McHenry The Journal of biological chemistry 1998 new
Divergence of a DNA replication gene cluster in the T4-related bacteriophage RB69. L S Yeh, Tien Hsu, Jim D Karam J Bacteriol 1998 complete
3'-Azido-3'-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes. Jingshan Ren, R M Esnouf, Andrew L Hopkins, E Yvonne Jones, I Kirby, J Keeling, C K Ross, Brendan A Larder, David I Stuart, David K Stammers Proceedings of the National Academy of Sciences of the United States of America 1998 topics set
In vivo protein interactions within the Escherichia coli DNA polymerase III core. Piotr Jonczyk, A Nowicka, I J Fijałkowska, Roel M Schaaper, Z Cieśla J Bacteriol 1998 pols set
The euryarchaeotes, a subdomain of Archaea, survive on a single DNA polymerase: fact or farce? Yoshizumi Ishino, Isaac K O Cann Genes Genet Syst 1998 new
Wheat DNA polymerase CI: a homologue of rat DNA polymerase beta. A E Luque, J P Benedetto, Michel Castroviejo Plant Mol Biol 1998 new
A novel DNA polymerase family found in Archaea. Yoshizumi Ishino, Kayoko Komori, Isaac K O Cann, Y Koga J Bacteriol 1998 new
Comparable sensitivity and specificity of nested PCR and single-stage PCR using a thermally activated DNA polymerase. K Zimmermann, J W Mannhalter BioTechniques 1998 new
Excision of C-4'-oxidized deoxyribose lesions from double-stranded DNA by human apurinic/apyrimidinic endonuclease (Ape1 protein) and DNA polymerase beta. Y J Xu, E Y Kim, Bruce Demple The Journal of biological chemistry 1998 new
A 6-basepair insert in the reverse transcriptase gene of human immunodeficiency virus type 1 confers resistance to multiple nucleoside inhibitors. M A Winters, K L Coolley, Y A Girard, D J Levee, H Hamdan, R W Shafer, D A Katzenstein, T C Merigan J Clin Invest 1998 topics set
The beta subunit sliding DNA clamp is responsible for unassisted mutagenic translesion replication by DNA polymerase III holoenzyme. Guy Tomer, N B Reuven, Zvi Livneh Proceedings of the National Academy of Sciences of the United States of America 1998 new
4-Hydroxy-17-methylincisterol, an inhibitor of DNA polymerase-alpha activity and the growth of human cancer cells in vitro. H Togashi, Yoshiyuki Mizushina, Masaharu Takemura, Fumio Sugawara, Hiroyuki Koshino, Y Esumi, J Uzawa, H Kumagai, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi Biochemical pharmacology 1998 pols set
Expression, purification, and initial kinetic characterization of the large subunit of the human mitochondrial DNA polymerase. S W Graves, Allison A Johnson, Kenneth A Johnson Biochemistry 1998 partial results
Endogenous reverse transcriptase assays reveal synergy between combinations of the M184V and other drug resistance-conferring mutations in interactions with nucleoside analog triphosphates. Yudong Quan, Z Gu, Xincang Li, Chen Liang, Michael A. Parniak, Mark A. Wainberg Journal of molecular biology 1998 pols set
Neutralizing antibodies directed against the V3 loop select for different escape variants in a virus with mutated reverse transcriptase (M184V) than in wild-type human immunodeficiency virus type 1. P Inouye, E Cherry, M Hsu, S Zolla-Pazner, Mark A. Wainberg AIDS research and human retroviruses 1998 pols set
Clamp subunit dissociation dictates bacteriophage T4 DNA polymerase holoenzyme disassembly. P Soumillion, D J Sexton, Stephen J Benkovic Biochemistry 1998 topics set
Characterization of human immunodeficiency virus type-1 (HIV-1) particles that express protease-reverse transcriptase fusion proteins. E Cherry, Chen Liang, Liwei Rong, Yudong Quan, P Inouye, Xincang Li, N Morin, M Kotler, Mark A. Wainberg Journal of molecular biology 1998 pols set
Effects of mutations in the polymerase domain on the polymerase, RNase H and strand transfer activities of human immunodeficiency virus type 1 reverse transcriptase. Hong Qiang Gao, Paul L Boyer, Edward Arnold, Stephen H Hughes Journal of molecular biology 1998 pols set
Pre-steady-state kinetics of nucleotide insertion following 8-oxo-7,8-dihydroguanine base pair mismatches by bacteriophage T7 DNA polymerase exo-. L L Furge, F Peter Guengerich Biochemistry 1998 pols set
A unified DNA- and dNTP-binding mode for DNA polymerases. Kamalendra Singh, Mukund J Modak Trends in biochemical sciences 1998 pols set
Coordinated leading and lagging strand DNA synthesis on a minicircular template. Joonsoo Lee, Paul D Chastain, T Kusakabe, Jack D Griffith, Charles C Richardson Molecular cell 1998 new
Examination of the role of DNA polymerase proofreading in the mutator effect of miscoding tRNAs. M M Slupska, A G King, L I Lu, R H Lin, E F Mao, C A Lackey, J H Chiang, C Baikalov, J H Miller J Bacteriol 1998 new
Role of the acidic carboxyl-terminal domain of the single-stranded DNA-binding protein of bacteriophage T7 in specific protein-protein interactions. D Kong, Charles C Richardson The Journal of biological chemistry 1998 pols set
Diminished HIV-1 sensitivity to stavudine in patients on prolonged therapy occurs only at low levels and cannot be attributed to any single amino acid substitution in reverse transcriptase. H Salomon, Julio S G Montaner, A Belmonte, Mark A. Wainberg Antiviral therapy 1998 pols set
Stable rearrangements of the beta3-beta4 hairpin loop of HIV-1 reverse transcriptase in plasma viruses from patients receiving combination therapy. C Tamalet, J Izopet, N Koch, J Fantini, N Yahi Aids 1998 new
4'-Acylated thymidine 5'-triphosphates: a tool to increase selectivity towards HIV-1 reverse transcriptase. Andreas Marx, Mario Amacker, M Stucki, Ulrich Hübscher, Thomas A Bickle, Bernd Giese Nucleic acids research 1998 pols set
Functional sites of human PCNA which interact with p21 (Cip1/Waf1), DNA polymerase delta and replication factor C. T Oku, S Ikeda, H Sasaki, K Fukuda, H Morioka, E Ohtsuka, Hirofumi Yoshikawa, Toshiki Tsurimoto Genes Cells 1998 new
Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t). Robert J Kokoska, L Stefanovic, H T Tran, Michael A Resnick, Dmitry A Gordenin, Thomas D Petes Molecular and cellular biology 1998 new
The base substitution and frameshift fidelity of Escherichia coli DNA polymerase III holoenzyme in vitro. P T Pham, M W Olson, Charles S McHenry, Roel M Schaaper The Journal of biological chemistry 1998 partial results
DNA polymerase fidelity: from genetics toward a biochemical understanding. Myron F Goodman, K D Fygenson Genetics 1998 complete
Effects of mutations on the partitioning of DNA substrates between the polymerase and 3'-5' exonuclease sites of DNA polymerase I (Klenow fragment). Wai-Chung Lam, Edwin J C Van der Schans, Catherine M Joyce, David P Millar Biochemistry 1998 pols set
Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates. C A Brautigam, Thomas A Steitz Journal of molecular biology 1998 topics set
1,1,3-Trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazine (TTD) derivatives: a new class of nonnucleoside human immunodeficiency virus type 1 (HIV-1) reverse transcriptase inhibitors with anti-HIV-1 activity. Myriam Witvrouw, M E Arranz, Christophe Pannecouque, R Declercq, H Jonckheere, J C Schmit, A-M Vandamme, J A Diaz, S T Ingate, J Desmyter, Robert Esnouf, L Van Meervelt, S Vega, Jan Balzarini, Erik De Clercq Antimicrobial agents and chemotherapy 1998 pols set
An N-terminal fragment of the gene 4 helicase/primase of bacteriophage T7 retains primase activity in the absence of helicase activity. David N Frick, K Baradaran, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 1998 pols set
Interactions between DNA polymerase beta and the major covalent adduct of the carcinogen (+)-anti-benzo[a]pyrene diol epoxide with DNA at a primer-template junction. S B Singh, William A Beard, B E Hingerty, Samuel H Wilson, Suse Broyde Biochemistry 1998 new
Inhibition of DNA polymerase reactions by pyrimidine nucleotide analogues lacking the 2-keto group. M J Guo, S Hildbrand, C J Leumann, L W McLaughlin, M J Waring Nucleic acids research 1998 pols set
A proline-to-histidine substitution at position 225 of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) sensitizes HIV-1 RT to BHAP U-90152. H Pelemans, R M Esnouf, Michael A. Parniak, A-M Vandamme, Erik De Clercq, Jan Balzarini The Journal of general virology 1998 pols set
The influence of 3TC-resistance mutations E89G and M184V in the human immunodeficiency virus reverse transcriptase on mispair extension efficiency. Monica E Hamburgh, William C Drosopoulos, Vinayaka R Prasad Nucleic acids research 1998 topics set
Different DNA polymerases are involved in the short- and long-patch base excision repair in mammalian cells. Paola Fortini, Barbara Pascucci, Eleonora Parlanti, Robert W Sobol, Samuel H Wilson, Eugenia Dogliotti Biochemistry 1998 new
Implication of the tRNA initiation step for human immunodeficiency virus type 1 reverse transcriptase in the mechanism of 3'-azido-3'-deoxythymidine (AZT) resistance. Joseph A Vaccaro, Karen S Anderson Biochemistry 1998 topics set
The relationship between the antitumor activity and the ribonucleotide reductase inhibitory activity of (E)-2'-deoxy-2'-(fluoromethylene) cytidine, MDL 101,731. J Kanazawa, Tomosaburo Takahashi, S Akinaga, T Tamaoki, M Okabe Anti-cancer drugs 1998 new
Top DNA polymerase from Thermus thermophilus HB27: gene cloning, sequence determination, and physicochemical properties. Joong Su Kim, S Koh, J J Kim, Suk-Tae Kwon, D S Lee Mol Cells 1998 pols set
Domain organization and biochemical features of Sulfolobus solfataricus DNA polymerase. Francesca M Pisani, Mariarita De Felice, G Manco, Mosè Rossi Extremophiles 1998 pols set
The antiherpesvirus activity of H2G [(R)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine] is markedly enhanced by the novel immunosuppressive agent mycophenolate mofetil. Johan Neyts, Graciella Andrei, Erik De Clercq Antimicrobial agents and chemotherapy 1998 new
Chromium(III) decreases the fidelity of human DNA polymerase beta. J Singh, E T Snow Biochemistry 1998 pols set
Lamivudine resistance of HIV type 1 does not delay development of resistance to nonnucleoside HIV type 1-specific reverse transcriptase inhibitors as compared with wild-type HIV type 1. H Jonckheere, Myriam Witvrouw, Erik De Clercq, J Anné AIDS research and human retroviruses 1998 pols set
Structure and processivity of two forms of Saccharomyces cerevisiae DNA polymerase delta. Peter M J Burgers, K J Gerik The Journal of biological chemistry 1998 partial results
HIV-specific cytotoxic T-lymphocyte activity in immunologically normal HIV-infected persons. N F Bernard, K Pederson, F Chung, L Ouellet, Mark A. Wainberg, C M Tsoukas AIDS (London, England) 1998 new
Long-term laboratory contamination by Mycobacterium abscessus resulting in two pseudo-outbreaks: recognition with use of random amplified polymorphic DNA (RAPD) polymerase chain reaction. K K Lai, B A Brown, J A Westerling, S A Fontecchio, Yongqing Zhang, Richard J Wallace Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1998 new
The role of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection. Erik De Clercq Antiviral research 1998 pols set
Mammalian base excision repair and DNA polymerase beta. Samuel H Wilson Mutation research 1998 new
Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps. Deepak K Srivastava, Brian J Vande Berg, Rajendra Prasad, J T Molina, William A Beard, Alan E Tomkinson, Samuel H Wilson The Journal of biological chemistry 1998 new
The novel immunosuppressive agent mycophenolate mofetil markedly potentiates the antiherpesvirus activities of acyclovir, ganciclovir, and penciclovir in vitro and in vivo. Johan Neyts, Graciella Andrei, Erik De Clercq Antimicrobial agents and chemotherapy 1998 new
Probing the binding region of the single-stranded DNA-binding domain of rat DNA polymerase beta using nanosecond-pulse laser-induced cross-linking and mass spectrometry. D A Connor, A M Falick, M C Young, M D Shetlar Photochem Photobiol 1998 new
Mammalian base excision repair by DNA polymerases delta and epsilon. M Stucki, Barbara Pascucci, Eleonora Parlanti, Paola Fortini, Samuel H Wilson, Ulrich Hübscher, Eugenia Dogliotti Oncogene 1998 new
Combined effects of interferon-alpha and acyclovir on herpes simplex virus type 1 DNA polymerase and alkaline DNase. J L Taylor, P Tom, W J O'Brien Antiviral Res 1998 new
Carboxyflavins, novel inhibitors of Taq DNA polymerase. Yoshiyuki Mizushina, T Ueno, Y Goto, Y Isobe, M Sako, T Fujita, Kouji Hirota, H Hayashi, Kengo Sakaguchi International journal of molecular medicine 1998 pols set
Creation of genetic information by DNA polymerase of the thermophilic bacterium Thermus thermophilus. Norio Ogata, T Miura Nucleic acids research 1998 new
A 5'-monophosphate form of bredinin selectively inhibits the activities of mammalian DNA polymerases in vitro. T Horie, Yoshiyuki Mizushina, Masaharu Takemura, Fumio Sugawara, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi International journal of molecular medicine 1998 new
Cloning, sequence analysis and expression in E. coli of the DNA polymerase I gene from Chloroflexus aurantiacus, a green nonsulfur eubacterium. M Tvermyr, B E Kristiansen, T Kristensen Genet Anal 1998 pols set
Analysis of strand slippage in DNA polymerase expansions of CAG/CTG triplet repeats associated with neurodegenerative disease. John Petruska, Michael J Hartenstine, Myron F Goodman The Journal of biological chemistry 1998 pols set
Effect of a 3'-->5' exonuclease with a proofreading function on the fidelity of error-prone DNA polymerase alpha from regenerating liver of aged rats. Takahiko Taguchi, T Toda, M Fukuda, Mochihiko Ohashi Mech Ageing Dev 1998 new
A mushroom fruiting body-inducing substance inhibits activities of replicative DNA polymerases. Yoshiyuki Mizushina, L Hanashima, Tsuyoshi Yamaguchi, Masaharu Takemura, Fumio Sugawara, Mineo Saneyoshi, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi Biochemical and biophysical research communications 1998 pols set
Sulfoquinovosyldiacylglycerol, KM043, a new potent inhibitor of eukaryotic DNA polymerases and HIV-reverse transcriptase type 1 from a marine red alga, Gigartina tenella. Keisuke Ohta, Yoshiyuki Mizushina, N Hirata, Masaharu Takemura, Fumio Sugawara, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi Chemical & pharmaceutical bulletin 1998 pols set
Role of the putative zinc finger domain of Saccharomyces cerevisiae DNA polymerase epsilon in DNA replication and the S/M checkpoint pathway. Rajiv Dua, Daniel L Levy, Judith L Campbell The Journal of biological chemistry 1998 pols set
Mutational analysis of phi29 DNA polymerase residues acting as ssDNA ligands for 3'-5' exonucleolysis. Miguel de Vega, José María Lázaro, Margarita Salas, Luis Blanco Journal of molecular biology 1998 pols set
Evidence for a Cdc6p-independent mitotic resetting event involving DNA polymerase alpha. C Desdouets, C Santocanale, L S Drury, G Perkins, Marco Foiani, Paolo Plevani, J F Diffley The EMBO journal 1998 new
Structural studies on an inhibitory antibody against Thermus aquaticus DNA polymerase suggest mode of inhibition. R Murali, M Helmer-Citterich, D J Sharkey, E R Scalice, J L Daiss, M A Sullivan, H M Krishna Murthy Protein Eng 1998 pols set
Identification of 5'-deoxyribose phosphate lyase activity in human DNA polymerase gamma and its role in mitochondrial base excision repair in vitro. Matthew J Longley, Rajendra Prasad, Deepak K Srivastava, Samuel H Wilson, William C Copeland Proceedings of the National Academy of Sciences of the United States of America 1998 pols set
Molecular constituents of the replication apparatus in the plasmodium of Physarum polycephalum: identification by photoaffinity labelling. Sabine Doerhoefer, S Khodyreva, I V Safronov, W A Wlassoff, R Anarbaev, Olga I Lavrik, Eggehard Holler Microbiology (Reading, England) 1998 new
Photoaffinity labeling of DNA polymerase from Thermus thermophilus and DNA template by photoreactive analogs of dCTP. A L Zakharenko, Svetlana N Khodyreva, Nadejda I Rechkunova, I V Safronov, Dmitriy V Pyshnyi, S K Degtyarev, Olga I Lavrik Biochemistry (Mosc) 1998 new
Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes. C A Brautigam, Thomas A Steitz Current opinion in structural biology 1998 new
S-1153 inhibits replication of known drug-resistant strains of human immunodeficiency virus type 1. Tsuyoshi Fujiwara, Akira Sato, M el-Farrash, S Miki, K Abe, Y Isaka, M Kodama, Y Wu, L B Chen, H Harada, H Sugimoto, Masami Hatanaka, Y Hinuma Antimicrobial agents and chemotherapy 1998 pols set
Structural insights into DNA polymerase beta fidelity: hold tight if you want it right. William A Beard, Samuel H Wilson Chemistry & biology 1998 new
Hybrid Ty1/HIV-1 elements used to detect inhibitors and monitor the activity of HIV-1 reverse transcriptase. D V Nissley, Paul L Boyer, D J Garfinkel, Stephen H Hughes, J N Strathern Proceedings of the National Academy of Sciences of the United States of America 1998 pols set
Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance. Y Hsiou, Kalyan Das, Jianping Ding, Arthur D Clark, Jörg-Peter Kleim, M Rösner, I Winkler, G Riess, Stephen H Hughes, Edward Arnold Journal of molecular biology 1998 topics set
Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. F J Palella, K M Delaney, A C Moorman, M O Loveless, J Fuhrer, G A Satten, D J Aschman, S D Holmberg N Engl J Med 1998 new
Characterization of the p125 subunit of human DNA polymerase delta and its deletion mutants. Interaction with cyclin-dependent kinase-cyclins. S M Wu, Peiming Zhang, X R Zeng, S J Zhang, J Mo, B Q Li, Marietta Y W T Lee The Journal of biological chemistry 1998 pols set
Stopped-flow fluorescence study of precatalytic primer strand base-unstacking transitions in the exonuclease cleft of bacteriophage T4 DNA polymerase. M R Otto, Linda B Bloom, Myron F Goodman, J M Beechem Biochemistry 1998 complete
New alkenyldiarylmethanes with enhanced potencies as anti-HIV agents which act as non-nucleoside reverse transcriptase inhibitors. Mark Cushman, A Casimiro-Garcia, E Hejchman, J A Ruell, M Huang, C A Schaeffer, K Williamson, W G Rice, Robert W Buckheit Journal of medicinal chemistry 1998 pols set
Generation of genomic mini-libraries by Taq DNA polymerase modification of genomic fragments. H J Huang, C Pears BioTechniques 1998 pols set
Synthesis and RNA polymerase incorporation of the degenerate ribonucleotide analogue rPTP. K Moriyama, Kazuo Negishi, M S Briggs, C L Smith, F Hill, M J Churcher, D M Brown, David Loakes Nucleic acids research 1998 topics set
Primase activity of human DNA polymerase alpha-primase. Divalent cations stabilize the enzyme activity of the p48 subunit. A Schneider, Richard W P Smith, A R Kautz, Klaus Weisshart, Frank Grosse, Heinz Peter Nasheuer The Journal of biological chemistry 1998 pols set
Effect of HIV constructs containing protease-reverse transcriptase fusion proteins on viral replication. E Cherry, N Morin, Mark A. Wainberg AIDS (London, England) 1998 pols set
Identification of a transient excision intermediate at the crossroads between DNA polymerase extension and proofreading pathways. R P Baker, Linda J Reha-Krantz Proceedings of the National Academy of Sciences of the United States of America 1998 complete
Impaired fitness of foscarnet-resistant strains of human immunodeficiency virus type 1. G Tachedjian, John W Mellors, H Bazmi, J Mills AIDS Res Hum Retroviruses 1998 topics set
Functional analysis of the amino-terminal 8-kDa domain of DNA polymerase beta as revealed by site-directed mutagenesis. DNA binding and 5'-deoxyribose phosphate lyase activities. Rajendra Prasad, William A Beard, J Y Chyan, Mark W Maciejewski, Gregory P Mullen, Samuel H Wilson The Journal of biological chemistry 1998 new
Thermodynamics of human DNA ligase I trimerization and association with DNA polymerase beta. E K Dimitriadis, Rajendra Prasad, M K Vaske, L Chen, Alan E Tomkinson, M S Lewis, Samuel H Wilson The Journal of biological chemistry 1998 pols set
DNA strand breaking by the hydroxyl radical is governed by the accessible surface areas of the hydrogen atoms of the DNA backbone. B Balasubramanian, W K Pogozelski, T D Tullius Proceedings of the National Academy of Sciences of the United States of America 1998 new
A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides. Mekbib Astatke, K Ng, Nigel D F Grindley, Catherine M Joyce Proceedings of the National Academy of Sciences of the United States of America 1998 pols set
A mechanism for all polymerases. Thomas A Steitz Nature 1998 new
DNA binding properties and processive proofreading of herpes simplex virus type 1 DNA polymerase. R Strick, Charles W Knopf Biochimica et biophysica acta 1998 new
DNA polymerase and topoisomerase II inhibitors from Psoralea corylifolia. N J Sun, S H Woo, J M Cassady, R M Snapka J Nat Prod 1998 new
An ergosterol peroxide, a natural product that selectively enhances the inhibitory effect of linoleic acid on DNA polymerase beta. Yoshiyuki Mizushina, I Watanabe, H Togashi, L Hanashima, Masaharu Takemura, Keisuke Ohta, Fumio Sugawara, Hiroyuki Koshino, Y Esumi, J Uzawa, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi Biol Pharm Bull 1998 pols set
Catalytic center of DNA polymerase beta for excision of deoxyribose phosphate groups. Yoshihiro Matsumoto, K Kim, D S Katz, J A Feng Biochemistry 1998 new
Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution. Jianping Ding, Kalyan Das, Y Hsiou, Stefan G Sarafianos, Arthur D Clark, A Jacobo-Molina, C Tantillo, Stephen H Hughes, Edward Arnold Journal of molecular biology 1998 topics set
In search of a mutational hotspot. Zafer Hatahet, Mian Zhou, Linda J Reha-Krantz, S W Morrical, Susan S Wallace Proceedings of the National Academy of Sciences of the United States of America 1998 complete
Penciclovir and pathogenesis phenotypes of drug-resistant Herpes simplex virus mutants. E Pelosi, G B Mulamba, Donald M Coen Antiviral research 1998 new
A single N-2-acetylaminofluorene adduct alters the footprint of T7 (exo-) DNA polymerase bound to a model primer-template junction. Dominique Y Burnouf, Robert P P Fuchs Mutation research 1998 new
Molecular basis for the antiviral and anticancer activities of unnatural L-beta-nucleosides. Silvio Spadari, Giovanni Maga, A Verri, Federico Focher Expert opinion on investigational drugs 1998 pols set
Virtues of being faithful: can we limit the genetic variation in human immunodeficiency virus? William C Drosopoulos, Lisa F Rezende, Mark A. Wainberg, Vinayaka R Prasad Journal of molecular medicine (Berlin, Germany) 1998 pols set
Use of the restriction enzyme AvaI and exo- Bst polymerase in strand displacement amplification. M A Milla, P A Spears, R E Pearson, G T Walker BioTechniques 1998 partial results
Multiple forms of DNA polymerase from the thermo-acidophilic eubacterium Bacillus acidocaldarius: purification, biochemical characterization and possible biological role. Mariarosaria De Falco, P Grippo, Mosè Rossi, P Orlando Biochem J 1998 new
Treatment of duck hepatitis B virus by antisense poly-2'-O-(2,4-dinitrophenyl)-oligoribonucleotides. W Xin, J H Wang Antisense & nucleic acid drug development 1998 new
Effect of inhibitors in clinical specimens on Taq and Tth DNA polymerase-based PCR amplification of influenza A virus. S K Poddar, M H Sawyer, J D Connor J Med Microbiol 1998 pols set
Purification, crystallization and preliminary X-ray crystallographic analysis of Pyrococcus furiosus DNA polymerase. S Goldman, R Kim, L W Hung, J Jancarik, S H Kim Acta Crystallogr D Biol Crystallogr 1998 pols set
Two different reactions involved in the primer/template-independent polymerization of dATP and dTTP by Taq DNA polymerase. K Hanaki, T Odawara, Noriyuki Nakajima, Y K Shimizu, C Nozaki, K Mizuno, T Muramatsu, Y Kuchino, H Yoshikura Biochem Biophys Res Commun 1998 pols set
Lithocholic acid, a putative tumor promoter, inhibits mammalian DNA polymerase beta. Akitsu Ogawa, Takashi Murate, Motoshi Suzuki, Y Nimura, Shonen Yoshida Jpn J Cancer Res 1998 pols set
Characterization of the native and recombinant catalytic subunit of human DNA polymerase gamma: identification of residues critical for exonuclease activity and dideoxynucleotide sensitivity. Matthew J Longley, P A Ropp, Susan E Lim, William C Copeland Biochemistry 1998 partial results
Regulation of DNA polymerase exonucleolytic proofreading activity: studies of bacteriophage T4 "antimutator" DNA polymerases. Linda J Reha-Krantz Genetics 1998 complete
Localization of bacterial DNA polymerase: evidence for a factory model of replication. K P Lemon, A D Grossman Science 1998 new
Up-regulation of base excision repair correlates with enhanced protection against a DNA damaging agent in mouse cell lines. K H Chen, F M Yakes, Deepak K Srivastava, R K Singhal, Robert W Sobol, Julie K Horton, Bennett Van Houten, Samuel H Wilson Nucleic acids research 1998 new
Subunits of human replication protein A are crosslinked by photoreactive primers synthesized by DNA polymerases. Olga I Lavrik, Heinz Peter Nasheuer, Klaus Weisshart, M S Wold, Rajendra Prasad, William A Beard, Samuel H Wilson, Alain Favre Nucleic acids research 1998 pols set
A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta. Peter E M Gibbs, William Glenn McGregor, Veronica M Maher, P Nisson, Christopher W Lawrence Proceedings of the National Academy of Sciences of the United States of America 1998 topics set
ATP binding to the Escherichia coli clamp loader powers opening of the ring-shaped clamp of DNA polymerase III holoenzyme. Manju M Hingorani, Mike E O'Donnell The Journal of biological chemistry 1998 new
Cloning, purification and characterization of DNA polymerase beta from Xenopus laevis--studies on its potential role in DNA-end joining. S Reichenberger, P Pfeiffer Eur J Biochem 1998 pols set
Vertical-scanning mutagenesis of a critical tryptophan in the minor groove binding track of HIV-1 reverse transcriptase. Molecular nature of polymerase-nucleic acid interactions. William A Beard, Katarzyna Bebenek, Thomas A Darden, Lin Li, Rajendra Prasad, Thomas A Kunkel, Samuel H Wilson The Journal of biological chemistry 1998 pols set
Recognition of sequence-directed DNA structure by the Klenow fragment of DNA polymerase I. T E Carver, David P Millar Biochemistry 1998 pols set
Human immunodeficiency virus type 1 reverse transcriptase expressing the K70E mutation exhibits a decrease in specific activity and processivity. Michael D Miller, P D Lamy, M D Fuller, A S Mulato, Nicolas A Margot, T Cihlar, J M Cherrington Molecular pharmacology 1998 pols set
Pre-steady state analysis of the assembly of wild type and mutant circular clamps of Escherichia coli DNA polymerase III onto DNA. Jeffrey G Bertram, Linda B Bloom, J Turner, Mike E O'Donnell, J M Beechem, Myron F Goodman The Journal of biological chemistry 1998 pols set
Fidelity of mutant HIV-1 reverse transcriptases: interaction with the single-stranded template influences the accuracy of DNA synthesis. Baek Kim, T R Hathaway, Lawrence A Loeb Biochemistry 1998 pols set
Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance. Hao Huang, R Chopra, G L Verdine, S C Harrison Science 1998 topics set
Enhanced binding of azidothymidine-resistant human immunodeficiency virus 1 reverse transcriptase to the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer. Bruno Canard, S R Sarfati, Charles C Richardson The Journal of biological chemistry 1998 topics set
Removal of polymerase-produced mutant sequences from PCR products. J Smith, P Modrich Proceedings of the National Academy of Sciences of the United States of America 1997 new
Inhibition of toxic activities of Bothrops asper venom and other crotalid snake venoms by a novel neutralizing mixture. G Borkow, J M Gutierrez, M Ovadia Toxicol Appl Pharmacol 1997 new
A genetic system to identify DNA polymerase beta mutator mutants. S L Washington, M S Yoon, A M Chagovetz, Shu-Xia Li, C A Clairmont, Bradley D Preston, Kristin A Eckert, Joann B Sweasy Proceedings of the National Academy of Sciences of the United States of America 1997 pols set
Phosphorylated retinoblastoma protein stimulates DNA polymerase alpha. Masaharu Takemura, T Kitagawa, Shunji Izuta, J Wasa, A Takai, Tetsu Akiyama, Shonen Yoshida Oncogene 1997 new
Localization of the active site of the alpha subunit of the Escherichia coli DNA polymerase III holoenzyme. D R Kim, Arthur E Pritchard, Charles S McHenry J Bacteriol 1997 pols set
Comparative enzymatic study of HIV-1 reverse transcriptase resistant to 2',3'-dideoxynucleotide analogs using the single-nucleotide incorporation assay. Takayuki Ueno, Hiroyuki Mitsuya Biochemistry 1997 topics set
Improvement of the 3'-5' exonuclease activity of Taq DNA polymerase by protein engineering in the active site. Y Park, H Choi, D S Lee, Y Kim Mol Cells 1997 pols set
[Effect of HH07A, A derivative of hainanensine, on DNA polymerase I]. Y M Ye, C X Xu Yao Xue Xue Bao 1997 new
Evolution of internal eliminated segments and scrambling in the micronuclear gene encoding DNA polymerase alpha in two Oxytricha species. D C Hoffman, D M Prescott Nucleic acids research 1997 new
Human immunodeficiency virus type 1 reverse transcriptase genotype and drug susceptibility changes in infected individuals receiving dideoxyinosine monotherapy for 1 to 2 years. M A Winters, R W Shafer, R A Jellinger, G Mamtora, T Gingeras, T C Merigan Antimicrobial agents and chemotherapy 1997 topics set
Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor. R M Esnouf, Jingshan Ren, Andrew L Hopkins, C K Ross, E Yvonne Jones, David K Stammers, David I Stuart Proceedings of the National Academy of Sciences of the United States of America 1997 topics set
The proofreading domain of Escherichia coli DNA polymerase I and other DNA and/or RNA exonuclease domains. M J Moser, W R Holley, A Chatterjee, I S Mian Nucleic acids research 1997 pols set
DNA polymerase delta isolated from Schizosaccharomyces pombe contains five subunits. S Zuo, E Gibbs, Zvi Kelman, Teresa S-F Wang, Mike E O'Donnell, Stuart A MacNeill, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1997 new
Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway. R A Bennett, D M Wilson, Donny Wong, Bruce Demple Proceedings of the National Academy of Sciences of the United States of America 1997 pols set
DNA polymerase beta: multiple conformational changes in the mechanism of catalysis. Xuejun Zhong, Smita S Patel, B G Werneburg, Ming-Daw Tsai Biochemistry 1997 new
Characterization of a DNA polymerase from the uncultivated psychrophilic archaeon Cenarchaeum symbiosum. C Schleper, R V Swanson, E J Mathur, E F DeLong J Bacteriol 1997 new
Inhibition of the hemorrhagic activity of Bothrops asper venom by a novel neutralizing mixture. G Borkow, J M Gutiérrez, M Ovadia Toxicon 1997 new
A DNA polymerase III holoenzyme-like subassembly from an extreme thermophilic eubacterium. Charles S McHenry, M Seville, M G Cull Journal of molecular biology 1997 new
Residues at the carboxy terminus of T4 DNA polymerase are important determinants for interaction with the polymerase accessory proteins. L D Goodrich, T C Lin, E K Spicer, C Jones, William H Konigsberg Biochemistry 1997 complete
Low fidelity mutants in the O-helix of Thermus aquaticus DNA polymerase I. Motoshi Suzuki, A K Avicola, L Hood, Lawrence A Loeb The Journal of biological chemistry 1997 pols set
A minor groove binding track in reverse transcriptase. Katarzyna Bebenek, William A Beard, Thomas A Darden, Lin Li, Rajendra Prasad, B A Luton, D G Gorenstein, Samuel H Wilson, Thomas A Kunkel Nat Struct Biol 1997 new
Evidence for a role for DNA polymerase beta in mammalian meiosis. A W Plug, C A Clairmont, E Sapi, Terry Ashley, Joann B Sweasy Proceedings of the National Academy of Sciences of the United States of America 1997 new
Base miscoding and strand misalignment errors by mutator Klenow polymerases with amino acid substitutions at tyrosine 766 in the O helix of the fingers subdomain. J B Bell, Kristin A Eckert, Catherine M Joyce, Thomas A Kunkel The Journal of biological chemistry 1997 new
Effects of mutations in the Exo III motif of the herpes simplex virus DNA polymerase gene on enzyme activities, viral replication, and replication fidelity. Ying T Hwang, B Y Liu, Donald M Coen, Charles B C Hwang J Virol 1997 new
Escherichia coli DNA polymerase II catalyzes chromosomal and episomal DNA synthesis in vivo. Sneha Rangarajan, G Gudmundsson, Zongxing Qiu, Patricia L Foster, Myron F Goodman Proceedings of the National Academy of Sciences of the United States of America 1997 pols set
Structural analyses of gp45 sliding clamp interactions during assembly of the bacteriophage T4 DNA polymerase holoenzyme. III. The Gp43 DNA polymerase binds to the same face of the sliding clamp as the clamp loader. G J Latham, D J Bacheller, P Pietroni, Peter H von Hippel The Journal of biological chemistry 1997 pols set
Specific inhibition of PCR by non-extendable oligonucleotides using a 5' to 3' exonuclease-deficient DNA polymerase. D Yu, M Mukai, Q Liu, C R Steinman BioTechniques 1997 pols set
Mechanism of bacteriophage T4 DNA holoenzyme assembly: the 44/62 protein acts as a molecular motor. Anthony J Berdis, Stephen J Benkovic Biochemistry 1997 topics set
Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69. Jianhong Wang, A K Sattar, C C Wang, Jim D Karam, William H Konigsberg, Thomas A Steitz Cell 1997 complete
DNA polymerase beta: structure-fidelity relationship from Pre-steady-state kinetic analyses of all possible correct and incorrect base pairs for wild type and R283A mutant. J Ahn, B G Werneburg, Ming-Daw Tsai Biochemistry 1997 topics set
In vitro evolution of terminal protein-containing genomes. J A Esteban, Luis Blanco, Laurentino Villar, Margarita Salas Proceedings of the National Academy of Sciences of the United States of America 1997 pols set
The fidelity of 3' misinsertion and mispair extension during DNA synthesis exhibited by two drug-resistant mutants of the reverse transcriptase of human immunodeficiency virus type 1 with Leu74-->Val and Glu89-->Gly. T Rubinek, M Bakhanashvili, R Taube, O Avidan, A Hizi Eur J Biochem 1997 topics set
DNA polymerase beta: analysis of the contributions of tyrosine-271 and asparagine-279 to substrate specificity and fidelity of DNA replication by pre-steady-state kinetics. V S Kraynov, B G Werneburg, Xuejun Zhong, H Lee, J Ahn, Ming-Daw Tsai Biochem J 1997 topics set
The catalytic subunit of the DNA polymerase of herpes simplex virus type 1 interacts specifically with the C terminus of the UL8 component of the viral helicase-primase complex. Howard S Marsden, G W McLean, E C Barnard, G J Francis, K MacEachran, Mary C Murphy, G McVey, A Cross, A P Abbotts, N D Stow J Virol 1997 new
Fidelity and mutational spectrum of Pfu DNA polymerase on a human mitochondrial DNA sequence. P André, A Kim, Konstantin Khrapko, William G Thilly Genome Res 1997 pols set
Development and use of an in vitro HSV-tk forward mutation assay to study eukaryotic DNA polymerase processing of DNA alkyl lesions. Kristin A Eckert, Suzanne E Hile, P L Vargo Nucleic acids research 1997 new
The Epstein-Barr virus (EBV) DNA polymerase accessory protein, BMRF1, activates the essential downstream component of the EBV oriLyt. Q Zhang, E Holley-Guthrie, J Q Ge, D Dorsky, S Kenney Virology 1997 pols set
Expression of the catalytic subunit (UL54) and the accessory protein (UL44) of human cytomegalovirus DNA polymerase in a coupled in vitro transcription/translation system. T Cihlar, M D Fuller, J M Cherrington Protein Expr Purif 1997 pols set
Purification and characterization of DNA polymerase alpha-associated replication protein A-dependent yeast DNA helicase A. Subhasis B Biswas, P H Chen, Esther E Biswas Biochemistry 1997 new
The acidic carboxyl terminus of the bacteriophage T7 gene 4 helicase/primase interacts with T7 DNA polymerase. S M Notarnicola, H L Mulcahy, Joonsoo Lee, Charles C Richardson The Journal of biological chemistry 1997 pols set
Comparison among DNA polymerases 1, 2 and 3 from maize embryo axes. A DNA primase activity copurifies with DNA polymerase 2. E García, D Orjuela, Y Camacho, J J Zúñiga, J Plasencia, J M Vázquez-Ramos Plant Mol Biol 1997 new
Hydrogen bonding revisited: geometric selection as a principal determinant of DNA replication fidelity. Myron F Goodman Proceedings of the National Academy of Sciences of the United States of America 1997 complete
Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants. H T Tran, J D Keen, M Kricker, Michael A Resnick, Dmitry A Gordenin Molecular and cellular biology 1997 new
Pathways of peroxynitrite oxidation of thiol groups. C Quijano, B Alvarez, R M Gatti, O Augusto, R Radi Biochem J 1997 new
Inhibition of klenow fragment (exo-) catalyzed DNA polymerization by (5R)-5,6-dihydro-5-hydroxythymidine and structural analogue 5,6-dihydro-5-methylthymidine. Marc M Greenberg, T J Matray Biochemistry 1997 pols set
The small subunit is required for functional interaction of DNA polymerase delta with the proliferating cell nuclear antigen. Jin-Qiu Zhou, H He, Cheng-Keat Tan, Kathleen M Downey, Antero G So Nucleic acids research 1997 pols set
Template directed incorporation of nucleotide mixtures using azole-nucleobase analogs. G C Hoops, Peiming Zhang, W T Johnson, Natasha Paul, Donald E Bergstrom, V Jo Davisson Nucleic acids research 1997 topics set
DNA polymerase delta, an essential enzyme for DNA transactions. R Hindges, Ulrich Hübscher Biol Chem 1997 new
Characterization of DNA polymerase from Pyrococcus sp. strain KOD1 and its application to PCR. Masahiro Takagi, Motomu Nishioka, H Kakihara, Masao Kitabayashi, Hirokazu Inoue, B Kawakami, M Oka, Tadayuki Imanaka Appl Environ Microbiol 1997 partial results
DNA polymerase inhibition assay (PIA) for the detection of drug-DNA interactions. T P Dooley, K L Weiland Methods in molecular biology (Clifton, N.J.) 1997 new
The thioredoxin binding domain of bacteriophage T7 DNA polymerase confers processivity on Escherichia coli DNA polymerase I. E Bedford, Stanley Tabor, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 1997 partial results
Synthesis and evaluation of oligodeoxyribonucleotides containing an aryl(trifluoromethyl)diazirine moiety as the cross-linking probe: photoaffinity labeling of mammalian DNA polymerase beta. Tsuyoshi Yamaguchi, K Suyama, K Narita, Satoru Kohgo, A Tomikawa, Mineo Saneyoshi Nucleic acids research 1997 pols set
Partial purification and characterization of the DNA polymerase from the cyanelles of Cyanophora paradoxa. M A White, J C Bailey, G C Cannon, S Heinhorst FEBS letters 1997 new
Characterization of an African swine fever virus 20-kDa DNA polymerase involved in DNA repair. M Oliveros, R J Yáñez, María L Salas, José Salas, E Viñuela, Luis Blanco The Journal of biological chemistry 1997 partial results
Dissociation of bacteriophage T4 DNA polymerase and its processivity clamp after completion of Okazaki fragment synthesis. T E Carver, D J Sexton, Stephen J Benkovic Biochemistry 1997 partial results
Proliferating cell nuclear antigen promotes DNA synthesis past template lesions by mammalian DNA polymerase delta. Dmitry Ju Mozzherin, Shinya Shibutani, Cheng-Keat Tan, Kathleen M Downey, Paul A Fisher Proceedings of the National Academy of Sciences of the United States of America 1997 pols set
The thiocarboxanilide nonnucleoside UC781 is a tight-binding inhibitor of HIV-1 reverse transcriptase. J Barnard, G Borkow, Michael A. Parniak Biochemistry 1997 pols set
Retention of replication fidelity by a DNA polymerase functioning in a distantly related environment. Holly Kloos Dressman, C C Wang, Jim D Karam, John W Drake Proceedings of the National Academy of Sciences of the United States of America 1997 complete
o29 DNA polymerase residue Lys383, invariant at motif B of DNA-dependent polymerases, is involved in dNTP binding. J Saturno, José María Lázaro, Francisco J Esteban, Luis Blanco, Margarita Salas Journal of molecular biology 1997 pols set
Crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III. B Guenther, R Onrust, A Sali, Mike E O'Donnell, John Kuriyan Cell 1997 topics set
Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II. C P Selby, A Sancar The Journal of biological chemistry 1997 new
Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism. M R Sawaya, Rajendra Prasad, Samuel H Wilson, J Kraut, H Pelletier Biochemistry 1997 partial results
Alanine-scanning mutations in the "primer grip" of p66 HIV-1 reverse transcriptase result in selective loss of RNA priming activity. M D Powell, M Ghosh, P S Jacques, K J Howard, Stuart F J Le Grice, J G Levin The Journal of biological chemistry 1997 pols set
Conferring RNA polymerase activity to a DNA polymerase: a single residue in reverse transcriptase controls substrate selection. G Gao, M Orlova, Millie M Georgiadis, W A Hendrickson, S P Goff Proceedings of the National Academy of Sciences of the United States of America 1997 pols set
Processive proofreading by the adenovirus DNA polymerase. Association with the priming protein reduces exonucleolytic degradation. A J King, W R Teertstra, Luis Blanco, Margarita Salas, Peter C van der Vliet Nucleic acids research 1997 partial results
Mutations within the primer grip region of HIV-1 reverse transcriptase result in loss of RNase H function. C Palaniappan, M Wisniewski, P S Jacques, Stuart F J Le Grice, P J Fay, Robert A Bambara The Journal of biological chemistry 1997 pols set
Inhibitory potency of R-region specific antisense oligonucleotides against in vitro DNA polymerization and template-switching reactions catalysed by HIV-1 reverse transcriptase. G Borkow, Dominique Arion, A Noronha, M Scartozzi, Masad J Damha, Michael A. Parniak Int J Biochem Cell Biol 1997 new
[DNA polymerase mediated amplification of DNA fragments using primers with mismatches in the 3'-region]. K B Ignatov, V M Kramarov, O L Uznadze, A I Miroshnikov Bioorg Khim 1997 new
Role of glutamine-151 of human immunodeficiency virus type-1 reverse transcriptase in RNA-directed DNA synthesis. Neerja Kaushik, D Harris, N Rege, Mukund J Modak, P N Yadav, V N Pandey Biochemistry 1997 pols set
A novel DNA polymerase in the hyperthermophilic archaeon, Pyrococcus furiosus: gene cloning, expression, and characterization. Takashi Uemori, Yuichi Sato, Ikunoshin Kato, H Doi, Yoshizumi Ishino Genes Cells 1997 new
A noncanonical poly(A) signal, UAUAAA, and flanking elements in Epstein-Barr virus DNA polymerase mRNA function in cleavage and polyadenylation assays. S C Silver Key, Joseph S Pagano Virology 1997 new
An invariant lysine residue is involved in catalysis at the 3'-5' exonuclease active site of eukaryotic-type DNA polymerases. Miguel de Vega, T Ilyina, José María Lázaro, Margarita Salas, Luis Blanco Journal of molecular biology 1997 topics set
Primer-directed mutagenesis of an intact plasmid by using Pwo DNA polymerase in long distance inverse PCR. R Hidajat, P McNicol BioTechniques 1997 new
Single-nucleotide polymorphism identification assays using a thermostable DNA polymerase and delayed extraction MALDI-TOF mass spectrometry. L A Haff, I P Smirnov Genome Res 1997 pols set
Cloning and sequence analysis of the DNA polymerase alpha gene of Leishmania donovani: comparison with the human homologue. K Luton, A M Johnson Biochem Biophys Res Commun 1997 new
Random mutagenesis of the poly(ADP-ribose) polymerase catalytic domain reveals amino acids involved in polymer branching. V Rolli, M O'Farrell, J Ménissier-de Murcia, Gilbert de Murcia Biochemistry 1997 new
Plasmid rolling circle replication: identification of the RNA polymerase-directed primer RNA and requirement for DNA polymerase I for lagging strand synthesis. M G Kramer, S A Khan, M Espinosa The EMBO journal 1997 new
[Effect of ionophore A23187 and verapamil on RNA and DNA polymerase activity in rat liver nuclei]. A A Kapralov Ukr Biokhim Zh 1997 new
DNA polymerase beta in abasic site repair: a structurally conserved helix-hairpin-helix motif in lesion detection by base excision repair enzymes. Gregory P Mullen, Samuel H Wilson Biochemistry 1997 new
Optimized PCR amplification of influenza A virus RNA using Tth DNA polymerase, incorporating uracil N glycosylase (UNG) in a single tube reaction. S K Poddar, M H Sawyer, J D Connor J Clin Lab Anal 1997 new
Crystal structure of a thermostable Bacillus DNA polymerase I large fragment at 2.1 A resolution. James R Kiefer, C Mao, Connie J Hansen, S L Basehore, Holly H Hogrefe, J C Braman, Lorena S Beese Structure (London, England : 1993) 1997 partial results
Investigations on the thermostability and function of truncated Thermus aquaticus DNA polymerase fragments. B Villbrandt, G Sagner, D Schomburg Protein Eng 1997 pols set
Pre-steady-state kinetic characterization of wild type and 3'-azido-3'-deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: implication of RNA directed DNA polymerization in the mechanism of AZT resistance. S G Kerr, Karen S Anderson Biochemistry 1997 topics set
Single-step kinetics of HIV-1 reverse transcriptase mutants responsible for virus resistance to nucleoside inhibitors zidovudine and 3-TC. R Krebs, U Immendörfer, S H Thrall, B M Wöhrl, R S Goody Biochemistry 1997 topics set
Structural features of phi29 single-stranded DNA-binding protein. II. Global conformation of phi29 single-stranded DNA-binding protein and the effects of complex formation on the protein and the single-stranded DNA. M S Soengas, C R Mateo, G Rivas, Margarita Salas, A U Acuña, C Gutiérrez The Journal of biological chemistry 1997 pols set
Inhibition of the ribonuclease H and DNA polymerase activities of HIV-1 reverse transcriptase by N-(4-tert-butylbenzoyl)-2-hydroxy-1-naphthaldehyde hydrazone. G Borkow, Ronald S Fletcher, J Barnard, Dominique Arion, Dimitrios Motakis, G I Dmitrienko, Michael A. Parniak Biochemistry 1997 new
Chemical barriers to human immunodeficiency virus type 1 (HIV-1) infection: retrovirucidal activity of UC781, a thiocarboxanilide nonnucleoside inhibitor of HIV-1 reverse transcriptase. G Borkow, J Barnard, T M Nguyen, A Belmonte, Mark A. Wainberg, Michael A. Parniak J Virol 1997 new
Direct cycle sequencing with delta Taq DNA polymerase. J Fan, R S Ranu DNA Seq 1997 pols set
Characterization of a processive form of the vaccinia virus DNA polymerase. W F McDonald, N Klemperer, Paula Traktman Virology 1997 partial results
Incorporation of the guanosine triphosphate analogs 8-oxo-dGTP and 8-NH2-dGTP by reverse transcriptases and mammalian DNA polymerases. Ashwini S Kamath-Loeb, A Hizi, Hironori Kasai, Lawrence A Loeb The Journal of biological chemistry 1997 topics set
The Saccharomyces cerevisiae DNA polymerase alpha catalytic subunit interacts with Cdc68/Spt16 and with Pob3, a protein similar to an HMG1-like protein. J Wittmeyer, T Formosa Molecular and cellular biology 1997 pols set
Mutations in yeast proliferating cell nuclear antigen define distinct sites for interaction with DNA polymerase delta and DNA polymerase epsilon. J C Eissenberg, R Ayyagari, X V Gomes, Peter M J Burgers Molecular and cellular biology 1997 new
Purification and characterization of the DNA polymerase alpha associated exonuclease: the RTH1 gene product. F X Zhu, Esther E Biswas, Subhasis B Biswas Biochemistry 1997 partial results
DNA polymerase delta is required for human mismatch repair in vitro. Matthew J Longley, A J Pierce, P Modrich The Journal of biological chemistry 1997 new
Measurement of deoxyuridine triphosphate and thymidine triphosphate in the extracts of thymidylate synthase-inhibited cells using a modified DNA polymerase assay. R W Horowitz, Haijiang Zhang, E L Schwartz, R D Ladner, S Wadler Biochem Pharmacol 1997 new
Role of the bacteriophage T7 and T4 single-stranded DNA-binding proteins in the formation of joint molecules and DNA helicase-catalyzed polar branch migration. D Kong, Nancy G Nossal, Charles C Richardson The Journal of biological chemistry 1997 complete
Mutagenesis of the positively charged conserved residues in the 5' exonuclease domain of Taq DNA polymerase. Y Kim, Joong Su Kim, Y Park, C S Chang, S W Suh, D S Lee Mol Cells 1997 pols set
A DNA polymerase alpha catalytic subunit is purified independently from the tissues at meiotic prometaphase I of a basidiomycete, Coprinus cinereus. Tomoyuki Sawado, Kengo Sakaguchi Biochem Biophys Res Commun 1997 new
Klenow fragment-DNA interaction required for the incorporation of nucleotides opposite guanine and O6-methylguanine. Thomas E Spratt Biochemistry 1997 pols set
Initiation of bacteriophage phi29 DNA replication in vivo: assembly of a membrane-associated multiprotein complex. Alicia Bravo, Margarita Salas Journal of molecular biology 1997 pols set
Phage phi29 protein p6 is in a monomer-dimer equilibrium that shifts to higher association states at the millimolar concentrations found in vivo. A M Abril, Margarita Salas, J M Andreu, José M Hermoso, G Rivas Biochemistry 1997 pols set
Kinetics of DNA polymerase I (Klenow fragment exo-) activity on damaged DNA templates: effect of proximal and distal template damage on DNA synthesis. Holly Miller, Arthur P Grollman Biochemistry 1997 partial results
Amino acid changes in a unique sequence of bacteriophage T7 DNA polymerase alter the processivity of nucleotide polymerization. X M Yang, Charles C Richardson The Journal of biological chemistry 1997 partial results
Increased activity and fidelity of DNA polymerase beta on single-nucleotide gapped DNA. A M Chagovetz, Joann B Sweasy, Bradley D Preston The Journal of biological chemistry 1997 new
Post-PCR labeling using Taq DNA polymerase. Zhixin Chen, D E Ruffner BioTechniques 1997 pols set
Incorporation of fludarabine and 1-beta-D-arabinofuranosylcytosine 5'-triphosphates by DNA polymerase alpha: affinity, interaction, and consequences. V Gandhi, P Huang, A J Chapman, F Chen, W Plunkett Clin Cancer Res 1997 pols set
Expression and characterization of the small subunit of human DNA polymerase delta. Younguk Sun, Yanan Jiang, Peiming Zhang, S J Zhang, Yanjiao Zhou, B Q Li, N L Toomey, Marietta Y W T Lee The Journal of biological chemistry 1997 pols set
An accessory protein of DNA polymerase alpha declines in function with increasing age. S D Miller, E A Crouch, David L Busbee Mutation research 1997 new
Hepatitis B virus replication and mutation are autoregulated by interactions between surface antigen and HBeAg and the HBV DNA polymerase: a functional model with therapeutic implications. R Sallie Med Hypotheses 1997 new
Assembly and disassembly of DNA polymerase holoenzyme. D J Sexton, Anthony J Berdis, Stephen J Benkovic Curr Opin Chem Biol 1997 topics set
Mechanism of bypass synthesis through an abasic site analog by DNA polymerase I. T Paz-Elizur, M Takeshita, Zvi Livneh Biochemistry 1997 topics set
Fidelity of Escherichia coli DNA polymerase III holoenzyme. The effects of beta, gamma complex processivity proteins and epsilon proofreading exonuclease on nucleotide misincorporation efficiencies. Linda B Bloom, Xinbin Chen, D K Fygenson, J Turner, Mike E O'Donnell, Myron F Goodman The Journal of biological chemistry 1997 partial results
The influence of the proliferating cell nuclear antigen-interacting domain of p21(CIP1) on DNA synthesis catalyzed by the human and Saccharomyces cerevisiae polymerase delta holoenzymes. E Gibbs, Zvi Kelman, Jacqueline M Gulbis, Mike E O'Donnell, John Kuriyan, Peter M J Burgers, Jerard Hurwitz The Journal of biological chemistry 1997 new
Evolution of RNA-binding specificity in T4 DNA polymerase. C C Wang, A Pavlov, Jim D Karam The Journal of biological chemistry 1997 complete
Production of a thermostable DNA polymerase by site-specific cleavage of a heat-eluted affinity fusion protein. T Gräslund, J Nilsson, A M Lindberg, M Uhlén, P A Nygren Protein Expr Purif 1997 pols set
Comparison of hyperthermia radiosensitization and DNA polymerase inactivation in human normal and melanoma cell lines of different radiosensitivities. G P Raaphorst, J P Mao, D P Yang, C E Ng Radiat Oncol Investig 1997 new
Heat-mediated activation of affinity-immobilized Taq DNA polymerase. J Nilsson, M Bosnes, F Larsen, P A Nygren, M Uhlén, J Lundeberg BioTechniques 1997 pols set
Production and evaluation of Taq DNA polymerase. C Leelayuwat, T Srisuk, R Paechaiyaphum, T Limpaiboon, A Romphruk, A Romphruk J Med Assoc Thai 1997 pols set
Strand displacement associated DNA synthesis catalyzed by the Epstein-Barr virus DNA polymerase. Tatsuya Tsurumi, H Yamada, T Daikoku, Y Yamashita, Yoshitaka Nishiyama Biochem Biophys Res Commun 1997 pols set
Thermo Sequenase DNA polymerase and T. acidophilum pyrophosphatase: new thermostable enzymes for DNA sequencing. P B Vander Horn, M C Davis, J J Cunniff, C Ruan, B F McArdle, S B Samols, J Szasz, G Hu, K M Hujer, S T Domke, S R Brummet, R B Moffett, Carl W Fuller BioTechniques 1997 new
PCNA and DNA polymerase delta catalytic subunit from Schizosaccharomyces pombe do not interact directly. I Tratner, K Piard, M Grenon, M Perderiset, Giuseppe Baldacci Biochem Biophys Res Commun 1997 new
Nucleotide-induced stable complex formation by HIV-1 reverse transcriptase. W Tong, C D Lu, S K Sharma, S Matsuura, Antero G So, Walter A Scott Biochemistry 1997 new
Expression in Escherichia coli of the thermostable DNA polymerase from Pyrococcus furiosus. Chengping Lu, H P Erickson Protein Expr Purif 1997 pols set
DNA polymerase epsilon from Drosophila melanogaster. N Aoyagi, Masahiko Oshige, Fumiko Hirose, Kazufumi Kuroda, Akio Matsukage, Kengo Sakaguchi Biochem Biophys Res Commun 1997 new
Structural analyses of gp45 sliding clamp interactions during assembly of the bacteriophage T4 DNA polymerase holoenzyme. II. The Gp44/62 clamp loader interacts with a single defined face of the sliding clamp ring. G J Latham, D J Bacheller, P Pietroni, Peter H von Hippel The Journal of biological chemistry 1997 pols set
Purification, cDNA cloning, and gene mapping of the small subunit of human DNA polymerase epsilon. Yingqian Li, Hitomi Asahara, V S Patel, S Zhou, Stuart Linn The Journal of biological chemistry 1997 pols set
Cloning and characterisation of a thermostable alpha-DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. TY. F Niehaus, B Frey, G Antranikian Gene 1997 new
Requirement of yeast DNA polymerase delta in post-replicational repair of UV-damaged DNA. Carlos A Torres-Ramos, Satya Prakash, Louise Prakash The Journal of biological chemistry 1997 new
Cloning, chromosomal localization, and interspecies interaction of mouse DNA polymerase delta small subunit (PolD2). R Hindges, Ulrich Hübscher Genomics 1997 new
Replication of template-primers containing propanodeoxyguanosine by DNA polymerase beta. Induction of base pair substitution and frameshift mutations by template slippage and deoxynucleoside triphosphate stabilization. Muhammed F Hashim, Nathalie Schnetz-Boutaud, Lawrence J Marnett The Journal of biological chemistry 1997 pols set
Role of protein-protein interactions in the function of replication protein A (RPA): RPA modulates the activity of DNA polymerase alpha by multiple mechanisms. K A Braun, Y Lao, Z He, C J Ingles, M S Wold Biochemistry 1997 new
Shift of DNA polymerase alpha nuclear distribution and activity in apoptotic human leukaemia cells. S Miscia, A Di Baldassarre, A Cataldi Biochem Biophys Res Commun 1997 new
DNA polymerase I in constitutive stable DNA replication in Escherichia coli. T Kogoma, R R Maldonado J Bacteriol 1997 pols set
Regulation of DNA metabolic enzymes upon induction of preB cell development and V(D)J recombination: up-regulation of DNA polymerase delta. R Jessberger, Primo Schär, P Robins, Elena Ferrari, B Riwar, Ulrich Hübscher Nucleic acids research 1997 new
The DNA polymerase alpha-primase complex couples DNA replication, cell-cycle progression and DNA-damage response. Marco Foiani, G Lucchini, Paolo Plevani Trends in biochemical sciences 1997 new
Accessory subunit of mitochondrial DNA polymerase from Drosophila embryos. Cloning, molecular analysis, and association in the native enzyme. Yazhen Wang, Carol L Farr, Laurie S Kaguni The Journal of biological chemistry 1997 new
The Escherichia coli polB locus is identical to dinA, the structural gene for DNA polymerase II. Characterization of Pol II purified from a polB mutant. Zongxing Qiu, Myron F Goodman The Journal of biological chemistry 1997 pols set
A second DNA polymerase activity in yeast mitochondria. P Lucas, P Laquel-Robert, Jacqueline Plissonneau, J Schaeffer, L Tarrago-Litvak, Michel Castroviejo C R Acad Sci III 1997 new
A major DNA binding protein encoded by BALF2 open reading frame of Epstein-Barr virus (EBV) forms a complex with other EBV DNA-binding proteins: DNAase, EA-D, and DNA polymerase. Y Zeng, J Middeldorp, J J Madjar, T Ooka Virology 1997 new
Molecular cloning of the cDNA for the catalytic subunit of plant DNA polymerase alpha and its cell-cycle dependent expression. Masayuki Yokoi, M Ito, M Izumi, Hiroshi Miyazawa, H Nakai, Fumio Hanaoka Genes Cells 1997 new
Involvement of the yeast DNA polymerase delta in DNA repair in vivo. L Giot, R Chanet, M Simon, C Facca, G Faye Genetics 1997 new
Novel DNA-binding characteristics of a protein associated with DNA polymerase-alpha in pea. S K Burton, J Van 't Ho, J A Bryant Plant J 1997 new
A variant of DNA polymerase beta acts as a dominant negative mutant. Nandan Bhattacharyya, Sanjeev Banerjee Proceedings of the National Academy of Sciences of the United States of America 1997 new
Biochemical and mutational studies of the 5'-3' exonuclease of DNA polymerase I of Escherichia coli. Y Xu, V Derbyshire, K Ng, Xiaojun Chen Sun, Nigel D F Grindley, Catherine M Joyce Journal of molecular biology 1997 pols set
Substrate and mispairing properties of 5-formyl-2'-deoxyuridine 5'-triphosphate assessed by in vitro DNA polymerase reactions. Masaru Yoshida, K Makino, H Morita, Hiroaki Terato, Y Ohyama, Hiroshi Ide Nucleic acids research 1997 pols set
Overexpression of DNA polymerase beta sensitizes mammalian cells to 2',3'-deoxycytidine and 3'-azido-3'-deoxythymidine. K Bouayadi, Jean-Sébastien Hoffmann, P Fons, M Tiraby, J P Reynes, Christophe Cazaux Cancer research 1997 pols set
Structural analyses of gp45 sliding clamp interactions during assembly of the bacteriophage T4 DNA polymerase holoenzyme. I. Conformational changes within the gp44/62-gp45-ATP complex during clamp loading. P Pietroni, M C Young, G J Latham, Peter H von Hippel The Journal of biological chemistry 1997 pols set
Lobucavir is phosphorylated in human cytomegalovirus-infected and -uninfected cells and inhibits the viral DNA polymerase. Daniel J Tenney, G Yamanaka, S M Voss, C W Cianci, A V Tuomari, A K Sheaffer, M Alam, Richard J Colonno Antimicrob Agents Chemother 1997 new
Dissociation of the protein primer and DNA polymerase after initiation of adenovirus DNA replication. A J King, W R Teertstra, Peter C van der Vliet The Journal of biological chemistry 1997 new
Distinct roles of E2F recognition sites as positive or negative elements in regulation of the DNA polymerase alpha 180 kDa catalytic subunit gene promoter during Drosophila development. Masamitsu Yamaguchi, Y Hayashi, Fumiko Hirose, Y Nishimoto, Akio Matsukage Nucleic acids research 1997 new
Genetic information 'created' by archaebacterial DNA polymerase. Norio Ogata, T Miura Biochem J 1997 new
Abasic translesion synthesis by DNA polymerase beta violates the "A-rule". Novel types of nucleotide incorporation by human DNA polymerase beta at an abasic lesion in different sequence contexts. E Efrati, G Tocco, R Eritja, Samuel H Wilson, Myron F Goodman The Journal of biological chemistry 1997 pols set
Effect of incorporation of cidofovir into DNA by human cytomegalovirus DNA polymerase on DNA elongation. Xiwen Xiong, J L Smith, M S Chen Antimicrob Agents Chemother 1997 pols set
Correction of hypermutability, N-methyl-N'-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6. A Umar, M Koi, J I Risinger, W E Glaab, K R Tindall, R D Kolodner, C R Boland, J C Barrett, Thomas A Kunkel Cancer research 1997 new
In vitro anti-HIV activity of biflavonoids isolated from Rhus succedanea and Garcinia multiflora. Y M Lin, H Anderson, M T Flavin, Y H Pai, E Mata-Greenwood, T Pengsuparp, J M Pezzuto, Raymond F Schinazi, Stephen H Hughes, F C Chen Journal of natural products 1997 pols set
Subunit-specific mutagenesis of the cysteine 280 residue of the reverse transcriptase of human immunodeficiency virus type 1: effects on sensitivity to a specific inhibitor of the RNase H activity. S Loya, Hong Qiang Gao, O Avidan, Paul L Boyer, Stephen H Hughes, A Hizi Journal of virology 1997 pols set
Mutations in the pol gene of human immunodeficiency virus type 1 in infected patients receiving didanosine and hydroxyurea combination therapy. A De Antoni, A Foli, J Lisziewicz, F Lori J Infect Dis 1997 topics set
Effect of RNA secondary structure on the kinetics of DNA synthesis catalyzed by HIV-1 reverse transcriptase. Zucai Suo, Kenneth A Johnson Biochemistry 1997 new
RNA secondary structure switching during DNA synthesis catalyzed by HIV-1 reverse transcriptase. Zucai Suo, Kenneth A Johnson Biochemistry 1997 new
Effect of RNA secondary structure on RNA cleavage catalyzed by HIV-1 reverse transcriptase. Zucai Suo, Kenneth A Johnson Biochemistry 1997 new
Protein-nucleic acid interactions and DNA conformation in a complex of human immunodeficiency virus type 1 reverse transcriptase with a double-stranded DNA template-primer. Jianping Ding, Stephen H Hughes, Edward Arnold Biopolymers 1997 pols set
Molecular modeling of HIV-1 reverse transcriptase drug-resistant mutant strains: implications for the mechanism of polymerase action. Marilyn B Kroeger Smith, Christopher J Michejda, Stephen H Hughes, Paul L Boyer, Paul A J Janssen, Koen Andries, Robert W Buckheit, Richard H Smith Protein engineering 1997 pols set
Synthesis and biological activity of novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 2-Aryl-substituted benzimidazoles. Thomas Roth, Marshall L Morningstar, Paul L Boyer, Stephen H Hughes, Robert W Buckheit, Christopher J Michejda Journal of medicinal chemistry 1997 pols set
Placement of tRNA primer on the primer-binding site requires pol gene expression in avian but not murine retroviruses. W Fu, B A Ortiz-Conde, R J Gorelick, Stephen H Hughes, A Rein Journal of virology 1997 new
Multiple biological roles associated with the Rous sarcoma virus 5' untranslated RNA U5-IR stem and loop. J T Miller, Z Ge, S Morris, Kalyan Das, J Leis Journal of virology 1997 new
Herpes simplex virus DNA replication. Paul E Boehmer, I. Robert Lehman Annual review of biochemistry 1997 new
Highly potent oxathiin carboxanilide derivatives with efficacy against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus isolates. Robert W Buckheit, M J Snow, V Fliakas-Boltz, T L Kinjerski, J D Russell, L A Pallansch, W G Brouwer, S S Yang Antimicrobial agents and chemotherapy 1997 pols set
Binding of RNA template to a complex of HIV-1 reverse transcriptase/primer/template. Bruno Canard, R Sarfati, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 1997 pols set
Combination of mutations in human immunodeficiency virus type 1 reverse transcriptase required for resistance to the carbocyclic nucleoside 1592U89. M Tisdale, T Alnadaf, D Cousens Antimicrobial agents and chemotherapy 1997 pols set
Bacteriophage phi29 DNA replication arrest caused by codirectional collisions with the transcription machinery. M Elías-Arnanz, Margarita Salas The EMBO journal 1997 pols set
In vitro selection for different mutational patterns in the HIV-1 reverse transcriptase using high and low selective pressure of the nonnucleoside reverse transcriptase inhibitor HBY 097. Jörg-Peter Kleim, I Winkler, M Rösner, R Kirsch, H Rübsamen-Waigmann, A Paessens, G Riess Virology 1997 pols set
Initial appearance of the 184Ile variant in lamivudine-treated patients is caused by the mutational bias of human immunodeficiency virus type 1 reverse transcriptase. W Keulen, N K Back, A van Wijk, Charles A B Boucher, Ben Berkhout J Virol 1997 topics set
Tetrahydronaphthalene lignan compounds as potent anti-HIV type 1 agents. H Hara, T Fujihashi, T Sakata, A Kaji, H Kaji AIDS research and human retroviruses 1997 pols set
Lack of correlation between in vitro and in vivo replication of precisely defined benz-a-anthracene adducted DNAs. A G McNees, Mike E O'Donnell, P H Horton, H Y Kim, S J Kim, C M Harris, Thomas M Harris, R Stephen Lloyd The Journal of biological chemistry 1997 pols set
Characteristics of the Pro225His mutation in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase that appears under selective pressure of dose-escalating quinoxaline treatment of HIV-1. H Pelemans, Robert Esnouf, A Dunkler, Michael A. Parniak, A-M Vandamme, Anna Karlsson, Erik De Clercq, Jörg-Peter Kleim, Jan Balzarini Journal of virology 1997 pols set
In vitro induction of human immunodeficiency virus type 1 variants resistant to 2'-beta-Fluoro-2',3'-dideoxyadenosine. M Tanaka, R V Srinivas, Takayuki Ueno, M F Kavlick, F K Hui, A Fridland, J S Driscoll, Hiroyuki Mitsuya Antimicrobial agents and chemotherapy 1997 pols set
Thermus thermophilis dnaX homolog encoding gamma- and tau-like proteins of the chromosomal replicase. Olga Yurieva, Maija Skangalis, John Kuriyan, Mike E O'Donnell The Journal of biological chemistry 1997 new
Mutagenesis by human immunodeficiency virus reverse transcriptase: incorporation of O6-methyldeoxyguanosine triphosphate. A Hizi, Ashwini S Kamath-Loeb, K D Rose, Lawrence A Loeb Mutation research 1997 pols set
Analysis of nucleotide insertion and extension at 8-oxo-7,8-dihydroguanine by replicative T7 polymerase exo- and human immunodeficiency virus-1 reverse transcriptase using steady-state and pre-steady-state kinetics. L L Furge, F Peter Guengerich Biochemistry 1997 pols set
Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions. Giovanni Maga, Mario Amacker, N Ruel, Ulrich Hübscher, Silvio Spadari Journal of molecular biology 1997 pols set
Incubation at the nonpermissive temperature induces deficiencies in UV resistance and mutagenesis in mouse mutant cells expressing a temperature-sensitive ubiquitin-activating enzyme (E1). H Ikehata, S Kaneda, F Yamao, T Seno, T Ono, Fumio Hanaoka Molecular and cellular biology 1997 new
HIV-1 nucleocapsid protein and replication protein A influence the strand displacement DNA synthesis of lentiviral reverse transcriptase. Mario Amacker, M Hottiger, R Mossi, Ulrich Hübscher AIDS (London, England) 1997 pols set
[New photoreactive N(4)-substituted dCTP analogues:synthesis, photochemical characteristics, and substrate properties in HIV-1 reverse transcriptase catalyzed DNA synthesis]. I V Safronov, N V Shcherbik, Svetlana N Khodyreva, V A Vlasov, M I Dobrikov, G V Shishkin, Olga I Lavrik Bioorganicheskaia khimiia 1997 pols set
Gene 4 DNA primase of bacteriophage T7 mediates the annealing and extension of ribo-oligonucleotides at primase recognition sites. T Kusakabe, Charles C Richardson The Journal of biological chemistry 1997 pols set
The inhibitory action of fatty acids on DNA polymerase beta. Yoshiyuki Mizushina, Shonen Yoshida, Akio Matsukage, Kengo Sakaguchi Biochimica et biophysica acta 1997 pols set
Enhanced generation of A:T-->T:A transversions in a recA730 lexA51(Def) mutant of Escherichia coli. M Watanabe-Akanuma, Roger Woodgate, Toshihiro Ohta Mutation research 1997 new
Identification of DNA replication and cell cycle proteins that interact with PCNA. G Loor, S J Zhang, Peiming Zhang, N L Toomey, Marietta Y W T Lee Nucleic acids research 1997 new
Mapping specific protein-protein interactions within the core component of the breast cell DNA synthesome. J M Coll, Robert J Hickey, E A Cronkey, H Y Jiang, L Schnaper, Marietta Y W T Lee, L Uitto, J E Syvaoja, Linda H Malkas Oncology research 1997 new
The large subunit of replication factor C is a substrate for caspase-3 in vitro and is cleaved by a caspase-3-like protease during Fas-mediated apoptosis. E Rhéaume, L Y Cohen, F Uhlmann, C Lazure, A Alam, Jerard Hurwitz, R P Sékaly, F Denis The EMBO journal 1997 new
A complex consisting of human replication factor C p40, p37, and p36 subunits is a DNA-dependent ATPase and an intermediate in the assembly of the holoenzyme. J Cai, E Gibbs, F Uhlmann, B Phillips, N Yao, Mike E O'Donnell, Jerard Hurwitz The Journal of biological chemistry 1997 new
Probing structure/function relationships of HIV-1 reverse transcriptase with styrene oxide N2-guanine adducts. E Forgacs, G Latham, William A Beard, Rajendra Prasad, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson, R Stephen Lloyd The Journal of biological chemistry 1997 pols set
Posttranscriptional modification of retroviral primers is required for late stages of DNA replication. B P Burnett, Charles S McHenry Proceedings of the National Academy of Sciences of the United States of America 1997 pols set
Misincorporation of dNTPs opposite 1,N2-ethenoguanine and 5,6,7,9-tetrahydro-7-hydroxy-9-oxoimidazo[1,2-a]purine in oligonucleotides by Escherichia coli polymerases I exo- and II exo-, T7 polymerase exo-, human immunodeficiency virus-1 reverse transcriptase, and rat polymerase beta. S Langouët, M Müller, F Peter Guengerich Biochemistry 1997 new
Combination of a drug targeting the cell with a drug targeting the virus controls human immunodeficiency virus type 1 resistance. F Lori, A G Malykh, A Foli, R Maserati, A De Antoni, L Minoli, D Padrini, A Degli Antoni, E Barchi, H Jessen, Mark A. Wainberg, R C Gallo, J Lisziewicz AIDS research and human retroviruses 1997 pols set
Higher fidelity of RNA-dependent DNA mispair extension by M184V drug-resistant than wild-type reverse transcriptase of human immunodeficiency virus type 1. M Hsu, P Inouye, L Rezende, N Richard, Zhongjie Li, Vinayaka R Prasad, Mark A. Wainberg Nucleic acids research 1997 pols set
Increased fidelity of drug-selected M184V mutated HIV-1 reverse transcriptase as the basis for the effectiveness of 3TC in HIV clinical trials. Mark A. Wainberg Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1997 pols set
Effects of mutations in Pr160gag-pol upon tRNA(Lys3) and Pr160gag-plo incorporation into HIV-1. J Mak, A Khorchid, Q Cao, Yangxin Huang, I Lowy, Michael A. Parniak, Vinayaka R Prasad, Mark A. Wainberg, Lawrence Kleiman Journal of molecular biology 1997 pols set
Report on an outbreak of postinjection abscesses due to Mycobacterium abscessus, including management with surgery and clarithromycin therapy and comparison of strains by random amplified polymorphic DNA polymerase chain reaction. A Villanueva, R V Calderon, B A Vargas, F Ruiz, S Aguero, Yongqing Zhang, B A Brown, Richard J Wallace Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1997 new
Zidovudine-resistant human immunodeficiency virus type 1 strains subcultured in the presence of both lamivudine and quinoxaline HBY 097 retain marked sensitivity to HBY 097 but not to lamivudine. Jan Balzarini, H Pelemans, G Riess, M Roesner, I Winkler, Erik De Clercq, Jörg-Peter Kleim The Journal of infectious diseases 1997 pols set
SIV/HIV-1 hybrid virus expressing the reverse transcriptase gene of HIV-1 remains sensitive to HIV-1-specific reverse transcriptase inhibitors after passage in rhesus macaques. Jan Balzarini, Erik De Clercq, K Uberla Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1997 pols set
Mutations at codon 184 in simian immunodeficiency virus reverse transcriptase confer resistance to the (-) enantiomer of 2',3'-dideoxy-3'-thiacytidine. E Cherry, M Slater, H Salomon, E Rud, Mark A. Wainberg Antimicrobial agents and chemotherapy 1997 new
Sulfated polysaccharides extracted from sea algae as potential antiviral drugs. Myriam Witvrouw, Erik De Clercq General pharmacology 1997 pols set
In search of a selective antiviral chemotherapy. Erik De Clercq Clinical microbiology reviews 1997 pols set
Identification of CFDD (common regulatory factor for DNA replication and DREF genes) and role of its binding site in regulation of the proliferating cell nuclear antigen gene promoter. Y Hayashi, Fumiko Hirose, Y Nishimoto, M Shiraki, M Yamagishi, Akio Matsukage, Masamitsu Yamaguchi The Journal of biological chemistry 1997 new
Induction of apoptosis by primary HIV-1 isolates correlates with productive infection in peripheral blood mononuclear cells. Y J Zhang, B Fadeel, V Hodara, E M Fenyö AIDS (London, England) 1997 new
Genomic cloning and chromosomal assignment of the E2F dimerization partner TFDP gene family. Yong Zhang, V S Venkatraj, S G Fischer, D Warburton, S P Chellappan Genomics 1997 new
The rnhB gene encoding RNase HII of Streptococcus pneumoniae and evidence of conserved motifs in eucaryotic genes. Y B Zhang, S Ayalew, S A Lacks Journal of bacteriology 1997 new
SRR-SB3, a disulfide-containing macrolide that inhibits a late stage of the replicative cycle of human immunodeficiency virus. Myriam Witvrouw, Jan Balzarini, Christophe Pannecouque, S Jhaumeer-Laulloo, J A Esté, Dominique Schols, Peter Cherepanov, J C Schmit, Zeger Debyser, A-M Vandamme, J Desmyter, S R Ramadas, Erik De Clercq Antimicrobial agents and chemotherapy 1997 pols set
Varicella-zoster virus thymidine kinase gene and antiherpetic pyrimidine nucleoside analogues in a combined gene/chemotherapy treatment for cancer. B Degrève, Graciella Andrei, M Izquierdo, J Piette, K Morin, E E Knaus, L I Wiebe, I Basrah, R T Walker, Erik De Clercq, Jan Balzarini Gene therapy 1997 new
Inhibition of replication of HIV in primary monocyte/macrophages by different antiviral drugs and comparative efficacy in lymphocytes. Stefano Aquaro, CF Perno, Emanuela Balestra, Jan Balzarini, A Cenci, M Francesconi, S Panti, F Serra, N Villani, Raffaele Caliò Journal of leukocyte biology 1997 pols set
Models which explain the inhibition of reverse transcriptase by HIV-1-specific (thio)carboxanilide derivatives. R M Esnouf, David I Stuart, Erik De Clercq, E Schwartz, Jan Balzarini Biochemical and biophysical research communications 1997 pols set
Reverse transcriptase fidelity and HIV-1 variation. Jan Balzarini, H Pelemans, Erik De Clercq, Anna Karlsson, Jörg-Peter Kleim Science (New York, N.Y.) 1997 new
Transcriptional regulation of the Drosophila-raf proto-oncogene by the DNA replication-related element (DRE)/DRE-binding factor (DREF) system. J R Ryu, T Y Choi, E J Kwon, W H Lee, Y Nishida, Y Hayashi, Akio Matsukage, Masamitsu Yamaguchi, M A Yoo Nucleic acids research 1997 new
The roles of the human immunodeficiency virus type 1 Pol protein and the primer binding site in the placement of primer tRNA(3Lys) onto viral genomic RNA. Chen Liang, Liwei Rong, N Morin, E Cherry, Yangxin Huang, Lawrence Kleiman, Mark A. Wainberg Journal of virology 1997 pols set
The importance of the A-rich loop in human immunodeficiency virus type 1 reverse transcription and infectivity. Chen Liang, Xincang Li, Liwei Rong, P Inouye, Yudong Quan, Lawrence Kleiman, Mark A. Wainberg Journal of virology 1997 pols set
Development of resistance of human immunodeficiency virus (HIV) to anti-HIV agents: how to prevent the problem? Erik De Clercq International journal of antimicrobial agents 1997 pols set
Cloning and analysis of the DNA polymerase-encoding gene from Thermus caldophilus GK24. Suk-Tae Kwon, Joong Su Kim, J H Park, H K Kim, D S Lee Mol Cells 1997 topics set
Protein-primed DNA replication: a transition between two modes of priming by a unique DNA polymerase. J Mendez, Luis Blanco, Margarita Salas The EMBO journal 1997 pols set
The antievolutionary component of antimutagenesis and anticarcinogenesis: where do mutation rates come from and where are they going? John W Drake Mutation research 1996 complete
dNTP binding site in rat DNA polymerase beta revealed by controlled proteolysis and azido photoprobe cross-linking. Deepak K Srivastava, R K Evans, A Kumar, William A Beard, Samuel H Wilson Biochemistry 1996 new
Herpes simplex virus type 1 DNA polymerase. Mutational analysis of the 3'-5'-exonuclease domain. F J Kühn, Charles W Knopf The Journal of biological chemistry 1996 new
Human immunodeficiency virus reverse transcriptase. Functional mutants obtained by random mutagenesis coupled with genetic selection in Escherichia coli. Baek Kim, T R Hathaway, Lawrence A Loeb The Journal of biological chemistry 1996 pols set
Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant. Kalyan Das, Jianping Ding, Y Hsiou, Arthur D Clark, H Moereels, Luc Koymans, Koen Andries, Rudi Pauwels, Paul A J Janssen, Paul L Boyer, Patrick K Clark, Richard H Smith, Marilyn B Kroeger Smith, Christopher J Michejda, Stephen H Hughes, Edward Arnold Journal of molecular biology 1996 topics set
DNA sequencing with [alpha-33P]-labeled ddNTP terminators: a new approach to DNA sequencing with Thermo Sequenase DNA polymerase. J Fan, R S Ranu, C Smith, C Ruan, Carl W Fuller BioTechniques 1996 new
Human immunodeficiency virus type 1 reverse transcriptase and early events in reverse transcription. E.J. Arts, Mark A. Wainberg Advances in virus research 1996 new
Replisome assembly reveals the basis for asymmetric function in leading and lagging strand replication. Alexander Yuzhakov, J Turner, Mike E O'Donnell Cell 1996 new
A smaller form of the sliding clamp subunit of DNA polymerase III is induced by UV irradiation in Escherichia coli. R Skaliter, T Paz-Elizur, Zvi Livneh The Journal of biological chemistry 1996 pols set
[Effect of alpha-tocopherol and nuclear tocopherol-binding proteins on DNA-polymerase activity of isolated nuclei and nuclear matrix]. G V Donchenko, G V Petrova, A A Kapralov Ukr Biokhim Zh 1996 new
Processing of O6-methylguanine by mismatch correction in human cell extracts. S Ceccotti, G Aquilina, Peter Macpherson, Masami Yamada, Peter Karran, Margherita Bignami Current biology : CB 1996 pols set
Detection and characterization of DNA polymerase activity in Entamoeba histolytica. A Makioka, Susumu Kobayashi, Toshifumi Takeuchi Parasitol Res 1996 pols set
Resistance to (-)-2',3'-dideoxy-3'-thiacytidine (3TC) in HIV-1 isolated from paediatric patients. Mark A. Wainberg, L Lewis, H Salomon, Z Gu, A Keller, Nick Cammack, J Goldsmith, J Church, Bonnie Spira, S Wheeler, P Pizzo Antiviral therapy 1996 pols set
Targeting HIV reverse transcriptase for anti-AIDS drug design: structural and biological considerations for chemotherapeutic strategies. Edward Arnold, Kalyan Das, Jianping Ding, P N Yadav, Y Hsiou, Paul L Boyer, Stephen H Hughes Drug design and discovery 1996 pols set
Stage specific expression of proliferating cell nuclear antigen and DNA polymerase delta from Plasmodium falciparum. P Horrocks, M Jackson, S Cheesman, J H White, B J Kilbey Mol Biochem Parasitol 1996 new
An N-terminal deletion mutant of simian virus 40 (SV40) large T antigen oligomerizes incorrectly on SV40 DNA but retains the ability to bind to DNA polymerase alpha and replicate SV40 DNA in vitro. Klaus Weisshart, M K Bradley, B M Weiner, C Schneider, I Moarefi, Ellen Fanning, A K Arthur J Virol 1996 new
Human immunodeficiency virus type 1 reverse transcriptase: role of Tyr115 in deoxynucleotide binding and misinsertion fidelity of DNA synthesis. A M Martín-Hernández, Esteban Domingo, L Menéndez-Arias The EMBO journal 1996 pols set
Single-step purification of recombinant wild-type and mutant HIV-1 reverse transcriptase. Ronald S Fletcher, G Holleschak, Eva Nagy, Dominique Arion, G Borkow, Z Gu, Mark A. Wainberg, Michael A. Parniak Protein expression and purification 1996 pols set
Protein-protein and protein-DNA interactions at the bacteriophage T4 DNA replication fork. Characterization of a fluorescently labeled DNA polymerase sliding clamp. D J Sexton, T E Carver, Anthony J Berdis, Stephen J Benkovic The Journal of biological chemistry 1996 topics set
Identification of the nuclear localization signal of mouse DNA primase: nuclear transport of p46 subunit is facilitated by interaction with p54 subunit. Takeshi Mizuno, T Okamoto, Masayuki Yokoi, M Izumi, Atsushi Kobayashi, T Hachiya, Katsuyuki Tamai, T Inoue, Fumio Hanaoka Journal of cell science 1996 new
Selection of bacteriophage T4 antimutator DNA polymerases: a link between proofreading and sensitivity to phosphonoacetic acid. Linda J Reha-Krantz, C Wong Mutation research 1996 complete
Heterogeneity of primer extension products in asymmetric PCR is due both to cleavage by a structure-specific exo/endonuclease activity of DNA polymerases and to premature stops. G Tombline, D Bellizzi, V Sgaramella Proceedings of the National Academy of Sciences of the United States of America 1996 pols set
Recognition of the primers containing different modified nucleotide units by the Klenow fragment of DNA polymerase I from E coli. T I Kolocheva, A S Levina, G A Nevinsky Biochimie 1996 pols set
Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy. A K Iversen, R W Shafer, K Wehrly, M A Winters, J I Mullins, B Chesebro, T C Merigan J Virol 1996 topics set
Nigranoic acid, a triterpenoid from Schisandra sphaerandra that inhibits HIV-1 reverse transcriptase. H D Sun, S X Qiu, L Z Lin, Z Y Wang, Z W Lin, T Pengsuparp, J M Pezzuto, H H Fong, G A Cordell, N R Farnsworth Journal of natural products 1996 pols set
[Tests related to nucleic acids and DNA: effects of time lag between sample collection and examination on HBV-DNA polymerase activity]. M Ohira, N Yamamoto, T Nagai, Hiromi Yoshida Rinsho byori. The Japanese journal of clinical pathology 1996 new
A thumb subdomain mutant of the large fragment of Escherichia coli DNA polymerase I with reduced DNA binding affinity, processivity, and frameshift fidelity. Dana T Minnick, Mekbib Astatke, Catherine M Joyce, Thomas A Kunkel The Journal of biological chemistry 1996 partial results
Significance of the O-helix residues of Escherichia coli DNA polymerase I in DNA synthesis: dynamics of the dNTP binding pocket. Neerja Kaushik, V N Pandey, Mukund J Modak Biochemistry 1996 topics set
The development and use of a DNA polymerase arrest assay for the evaluation of parameters affecting intrastrand tetraplex formation. M N Weitzmann, K J Woodford, K Usdin The Journal of biological chemistry 1996 new
Specific inhibition of human immunodeficiency virus type 1 reverse transcriptase mediated by soulattrolide, a coumarin isolated from the latex of calophyllum teysmannii. T Pengsuparp, M Serit, Stephen H Hughes, D D Soejarto, J M Pezzuto Journal of natural products 1996 pols set
Highly favorable antiviral activity and resistance profile of the novel thiocarboxanilide pentenyloxy ether derivatives UC-781 and UC-82 as inhibitors of human immunodeficiency virus type 1 replication. Jan Balzarini, H Pelemans, Stefano Aquaro, CF Perno, Myriam Witvrouw, Dominique Schols, Erik De Clercq, Anna Karlsson Molecular pharmacology 1996 pols set
Evidence that the nuclease activities associated with the herpes simplex type 1 DNA polymerase are due to the 3'-5' exonuclease. J D Hall, K L Orth, D Claus-Walker J Virol 1996 new
Structural and functional organization of the DNA polymerase of bacteriophage T7. Xiaowen Yang, Charles C Richardson The Journal of biological chemistry 1996 pols set
Dynamics of loading the beta sliding clamp of DNA polymerase III onto DNA. Linda B Bloom, J Turner, Zvi Kelman, J M Beechem, Mike E O'Donnell, Myron F Goodman The Journal of biological chemistry 1996 new
Forward mutation rate of human immunodeficiency virus type 1 in a T lymphoid cell line. L M Mansky AIDS Res Hum Retroviruses 1996 new
The fission yeast Cdc1 protein, a homologue of the small subunit of DNA polymerase delta, binds to Pol3 and Cdc27. Stuart A MacNeill, S Moreno, N Reynolds, P Nurse, P A Fantes The EMBO journal 1996 pols set
Random mutagenesis of Thermus aquaticus DNA polymerase I: concordance of immutable sites in vivo with the crystal structure. Motoshi Suzuki, D Baskin, L Hood, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1996 pols set
Using 2-aminopurine fluorescence and mutational analysis to demonstrate an active role of bacteriophage T4 DNA polymerase in strand separation required for 3' --> 5'-exonuclease activity. L A Marquez, Linda J Reha-Krantz The Journal of biological chemistry 1996 complete
Primer-terminus stabilization at the 3'-5' exonuclease active site of phi29 DNA polymerase. Involvement of two amino acid residues highly conserved in proofreading DNA polymerases. Miguel de Vega, J M Lazaro, Margarita Salas, Luis Blanco The EMBO journal 1996 pols set
A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta. H Pelletier, M R Sawaya, W Wolfle, Samuel H Wilson, J Kraut Biochemistry 1996 topics set
(Alkylamino) piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1IIIB with reduced replication phenotypes. R A Olmsted, D E Slade, L A Kopta, S M Poppe, T J Poel, S W Newport, K B Rank, C Biles, R A Morge, T J Dueweke, Y Yagi, D L Romero, R C Thomas, S K Sharma, W G Tarpley Journal of virology 1996 pols set
Selective pressure of a quinoxaline nonnucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) on HIV-1 replication results in the emergence of nucleoside RT-inhibitor-specific (RT Leu-74-->Val or Ile and Val-75-->Leu or Ile) HIV-1 mutants. Jörg-Peter Kleim, M Rösner, I Winkler, A Paessens, R Kirsch, Y Hsiou, Edward Arnold, G Riess Proceedings of the National Academy of Sciences of the United States of America 1996 pols set
Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts. W Lewis, E S Levine, B Griniuviene, K O Tankersley, J M Colacino, J P Sommadossi, K A Watanabe, Fred W Perrino Proceedings of the National Academy of Sciences of the United States of America 1996 topics set
XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro. K W Caldecott, Said Aoufouchi, P Johnson, S Shall Nucleic acids research 1996 new
Reconstitution of repair-gap UV mutagenesis with purified proteins from Escherichia coli: a role for DNA polymerases III and II. Guy Tomer, O Cohen-Fix, Mike E O'Donnell, M Goodman, Zvi Livneh Proceedings of the National Academy of Sciences of the United States of America 1996 new
Requirement of mammalian DNA polymerase-beta in base-excision repair. Robert W Sobol, Julie K Horton, R Kühn, H Gu, R K Singhal, Rajendra Prasad, Klaus Rajewsky, Samuel H Wilson Nature 1996 pols set
The algorithm of estimation of the Km values for primers in DNA synthesis catalyzed by human DNA polymerase alpha. T I Kolocheva, G A Maksakova, O D Zakharova, G A Nevinsky FEBS letters 1996 pols set
Beta*, a UV-inducible shorter form of the beta subunit of DNA polymerase III of Escherichia coli. II. Overproduction, purification, and activity as a polymerase processivity clamp. R Skaliter, M Bergstein, Zvi Livneh The Journal of biological chemistry 1996 pols set
Structure of unliganded HIV-1 reverse transcriptase at 2.7 A resolution: implications of conformational changes for polymerization and inhibition mechanisms. Y Hsiou, Jianping Ding, Kalyan Das, Arthur D Clark, Stephen H Hughes, Edward Arnold Structure (London, England : 1993) 1996 topics set
Multiple regulatory events influence human cytomegalovirus DNA polymerase (UL54) expression during viral infection. J A Kerry, M A Priddy, T Y Jervey, C P Kohler, T L Staley, C D Vanson, T R Jones, A C Iskenderian, D G Anders, R M Stenberg J Virol 1996 pols set
3'-->5' exonucleases of DNA polymerases epsilon and delta correct base analog induced DNA replication errors on opposite DNA strands in Saccharomyces cerevisiae. Polina V Shcherbakova, Youri I Pavlov Genetics 1996 new
Probing the higher order structure of RNA with peroxonitrous acid. Matthias Götte, Roland Marquet, Catherine Isel, V E Anderson, G Keith, H J Gross, Chantal Ehresmann, Bernard Ehresmann, H Heumann FEBS letters 1996 new
Modulation by dietary copper of aflatoxin B1-induced activity of DNA repair enzymes poly (ADP-ribose) polymerase, DNA polymerase beta and DNA ligase. R P Webster, M D Gawde, R K Bhattacharya In Vivo 1996 new
DNA polymerase epsilon may be dispensable for SV40- but not cellular-DNA replication. T Zlotkin, Gabriel Kaufmann, Yanan Jiang, Marietta Y W T Lee, L Uitto, J Syväoja, I Dornreiter, Ellen Fanning, Tamar Nethanel The EMBO journal 1996 new
Probing the protein-DNA contacts of a yeast RNA polymerase III transcription complex in a crude extract: solid phase synthesis of DNA photoaffinity probes containing a novel photoreactive deoxycytidine analog. B J Lannutti, J Persinger, B Bartholomew Biochemistry 1996 topics set
Selective amplification of RNA utilizing the nucleotide analog dITP and Thermus thermophilus DNA polymerase. T Auer, J J Sninsky, D H Gelfand, T W Myers Nucleic acids research 1996 topics set
On the presence of DNA polymerase alpha in human lymphocyte nuclei and chromosomes. Maria Grazia Ennas, Hiroshi Suzuki, M Menegazzi, A Carcereri, Fumio Hanaoka, F Gremo, Mariella Nieddu, R Mezzanotte Heredity 1996 new
Direct cloning of PCR products amplified with Pwo DNA polymerase. S Hinnisdaels, J Del-Favero, M Vauterin BioTechniques 1996 new
A DNA binding motif coordinating synthesis and degradation in proofreading DNA polymerases. Verónica Truniger, José María Lázaro, Margarita Salas, Luis Blanco The EMBO journal 1996 new
dNTP binding to HIV-1 reverse transcriptase and mammalian DNA polymerase beta as revealed by affinity labeling with a photoreactive dNTP analog. Olga I Lavrik, Rajendra Prasad, William A Beard, I V Safronov, M I Dobrikov, Deepak K Srivastava, G V Shishkin, T G Wood, Samuel H Wilson The Journal of biological chemistry 1996 topics set
Replication across O6-methylguanine by human DNA polymerase beta in vitro. Insights into the futile cytotoxic repair and mutagenesis of O6-methylguanine. J Singh, L Su, E T Snow The Journal of biological chemistry 1996 pols set
Mutants in the Exo I motif of Escherichia coli dnaQ: defective proofreading and inviability due to error catastrophe. I Fijalkowska, Roel M Schaaper Proceedings of the National Academy of Sciences of the United States of America 1996 new
Coupling of a replicative polymerase and helicase: a tau-DnaB interaction mediates rapid replication fork movement. Sangbumn Kim, H Garry Dallmann, Charles S McHenry, K J Marians Cell 1996 new
Either bacteriophage T4 RNase H or Escherichia coli DNA polymerase I is essential for phage replication. L J Hobbs, Nancy G Nossal J Bacteriol 1996 pols set
A model for DNA polymerase translocation: worm-like movement of DNA within the binding cleft. W A Wlassoff, G M Dymshits, Olga I Lavrik FEBS letters 1996 new
Effectiveness of 3TC in HIV clinical trials may be due in part to the M184V substitution in 3TC-resistant HIV-1 reverse transcriptase. Mark A. Wainberg, M Hsu, Z Gu, G Borkow, Michael A. Parniak AIDS (London, England) 1996 pols set
tau couples the leading- and lagging-strand polymerases at the Escherichia coli DNA replication fork. Sangbumn Kim, H Garry Dallmann, Charles S McHenry, K J Marians The Journal of biological chemistry 1996 new
Identification of the beta-binding domain of the alpha subunit of Escherichia coli polymerase III holoenzyme. D R Kim, Charles S McHenry The Journal of biological chemistry 1996 pols set
Activation of the human DNA polymerase beta promoter by a DNA-alkylating agent through induced phosphorylation of cAMP response element-binding protein-1. Satya Narayan, Feng He, Samuel H Wilson The Journal of biological chemistry 1996 pols set
Enhancement of melphalan activity by inhibition of DNA polymerase-alpha and DNA polymerase-beta. K Moynihan, G B Elion, F Ali-Osman, S Marcelli, S Keir, D D Bigner, H S Friedman Cancer Chemother Pharmacol 1996 new
Preparations of duck hepatitis B virions contain multiple DNA polymerase activities. S M Oberhaus, J E Newbold Virology 1996 new
Reverse transcription, amplification and sequencing of poliovirus RNA by Taq DNA polymerase. V I Grabko, L G Chistyakova, V N Lyapustin, V G Korobko, A I Miroshnikov FEBS letters 1996 pols set
Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity. H Pelletier, M R Sawaya, W Wolfle, Samuel H Wilson, J Kraut Biochemistry 1996 pols set
Differential discrimination of DNA polymerase for variants of the non-standard nucleobase pair between xanthosine and 2,4-diaminopyrimidine, two components of an expanded genetic alphabet. Michael J Lutz, H A Held, M Hottiger, Ulrich Hübscher, Steven A Benner Nucleic acids research 1996 pols set
Crystal structures of an NH2-terminal fragment of T4 DNA polymerase and its complexes with single-stranded DNA and with divalent metal ions. Jianhong Wang, Pengbo Yu, T C Lin, William H Konigsberg, Thomas A Steitz Biochemistry 1996 complete
Structure of Taq polymerase with DNA at the polymerase active site. Soo Hyun Eom, Jianhong Wang, Thomas A Steitz Nature 1996 topics set
Inhibition of murine leukemia virus with poly-2'-O-(2,4-dinitrophenyl)poly[A]. M A Ashun, Y Hu, I Kang, C C Li, Jing-Houng Wang Antimicrobial agents and chemotherapy 1996 new
Use of Vibrio spp. for expression of Escherichia coli enterotoxin B subunit fusion proteins: purification and characterization of a chimera containing a C-terminal fragment of DNA polymerase from herpes simplex virus type 1. Arianna Loregian, T R Hirst, Howard S Marsden, Giorgio Palù Protein Expr Purif 1996 new
Differences in the inhibition of human immunodeficiency virus type 1 reverse transcriptase DNA polymerase activity by analogs of nevirapine and [2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro-5"-(4"-amino-1", 2"-oxathiole-2",2"-dioxide] (TSAO). Dominique Arion, Ronald S Fletcher, G Borkow, María-José Camarasa, Jan Balzarini, G I Dmitrienko, Michael A. Parniak Molecular pharmacology 1996 pols set
Fidelity and predominant mutations produced by deep vent wild-type and exonuclease-deficient DNA polymerases during in vitro DNA amplification. Hao Huang, P Keohavong DNA Cell Biol 1996 partial results
The joining (J) chain is present in invertebrates that do not express immunoglobulins. T Takahashi, T Iwase, N Takenouchi, M Saito, K Kobayashi, Z Moldoveanu, J Mestecky, I Moro Proceedings of the National Academy of Sciences of the United States of America 1996 new
Human Immunodeficiency Virus type 1 reverse transcriptase. M Hottiger, Ulrich Hübscher Biological chemistry Hoppe-Seyler 1996 pols set
Identification of novel thiocarboxanilide derivatives that suppress a variety of drug-resistant mutant human immunodeficiency virus type 1 strains at a potency similar to that for wild-type virus. Jan Balzarini, W G Brouwer, D C Dao, E M Osika, Erik De Clercq Antimicrobial agents and chemotherapy 1996 pols set
Human immunodeficiency virus type-1 reverse transcriptase. Contribution of Met-184 to binding of nucleoside 5'-triphosphate. J E Wilson, A Aulabaugh, B Caligan, S McPherson, J K Wakefield, S Jablonski, C D Morrow, J E Reardon, Phillip A Furman The Journal of biological chemistry 1996 pols set
Mechanism of translesion DNA synthesis by DNA polymerase II. Comparison to DNA polymerases I and III core. T Paz-Elizur, M Takeshita, M Goodman, Mike E O'Donnell, Zvi Livneh The Journal of biological chemistry 1996 new
Tau protects beta in the leading-strand polymerase complex at the replication fork. Sangbumn Kim, H Garry Dallmann, Charles S McHenry, K J Marians The Journal of biological chemistry 1996 new
Chemical crosslinking of the subunits of HIV-1 reverse transcriptase. Zeger Debyser, Erik De Clercq Protein science : a publication of the Protein Society 1996 pols set
Potent inhibition of human immunodeficiency virus and herpes simplex virus type 1 by 9-(2-phosphonylmethoxyethyl)adenine in primary macrophages is determined by drug metabolism, nucleotide pools, and cytokines. CF Perno, Emanuela Balestra, Stefano Aquaro, S Panti, A Cenci, G Lazzarino, B Tavazzi, D Di Pierro, Jan Balzarini, R Calio Molecular pharmacology 1996 pols set
Transcriptional regulation of the Drosophila CycA gene by the DNA replication-related element (DRE) and DRE binding factor (DREF). Katsuhito Ohno, Fumiko Hirose, Kengo Sakaguchi, Y Nishida, Akio Matsukage Nucleic acids research 1996 pols set
Elevated expression of DNA polymerase beta gene in glioma cell lines with acquired resistance to 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3- nitrosourea. A Gomi, S Shinoda, R Sakai, H Hirai, Kiyoshi Ozawa, T Masuzawa Biochem Biophys Res Commun 1996 new
The mammalian DNA polymerase delta--proliferating cell nuclear antigen--template-primer complex: molecular characterization by direct binding. Maeve McConnell, Holly Miller, Dmitry Ju Mozzherin, A Quamina, Cheng-Keat Tan, Kathleen M Downey, Paul A Fisher Biochemistry 1996 pols set
Multiple forms of tRNA(Lys3) in HIV-1. Zhongjie Li, A Shalom, Yangxin Huang, J Mak, E Arts, Mark A. Wainberg, Lawrence Kleiman Biochemical and biophysical research communications 1996 pols set
An accessory protein enhances both DNA binding and activity of DNA polymerase alpha isolated from normal, but not transformed, human fibroblasts. M Schroeder, S Miller, V Srivastava, E Merriam-Crouch, S Holt, V Wilson, D Busbee Mutation research 1996 new
Analysis of inhibition of retroviral reverse transcriptase. Jan Balzarini, Erik De Clercq Methods in enzymology 1996 new
Crystal structures of complexes of a peptidic inhibitor with wild-type and two mutant HIV-1 proteases. L Hong, A Treharne, J A Hartsuck, S Foundling, J Tang Biochemistry 1996 new
DNA polymerases alpha and beta are required for DNA repair in an efficient nuclear extract from Xenopus oocytes. N Oda, J K Saxena, T M Jenkins, Rajendra Prasad, Samuel H Wilson, E J Ackerman The Journal of biological chemistry 1996 new
Nuclear matrix bound DNA polymerase-beta in mouse fibrosarcoma: effect of gamma-radiation. C K Nair, A Mukherjee, B B Singh Indian J Exp Biol 1996 new
Elucidation of the metal-binding properties of the Klenow fragment of Escherichia coli polymerase I and bacteriophage T4 DNA polymerase by lanthanide(III) luminescence spectroscopy. M W Frey, S T Frey, W D Horrocks, B F Kaboord, Stephen J Benkovic Chemistry & biology 1996 pols set
Molecular cloning of Drosophila mus308, a gene involved in DNA cross-link repair with homology to prokaryotic DNA polymerase I genes. P V Harris, O M Mazina, E A Leonhardt, R B Case, J B Boyd, K C Burtis Molecular and cellular biology 1996 new
Age-associated changes in the template-reading fidelity of DNA polymerase alpha from regenerating rat liver. Takahiko Taguchi, Mochihiko Ohashi Mech Ageing Dev 1996 new
Base analog N6-hydroxylaminopurine mutagenesis in Escherichia coli: genetic control and molecular specificity. Youri I Pavlov, V V Suslov, Polina V Shcherbakova, Thomas A Kunkel, A Ono, A Matsuda, Roel M Schaaper Mutation research 1996 new
Substitution of mucAB or rumAB for umuDC alters the relative frequencies of the two classes of mutations induced by a site-specific T-T cyclobutane dimer and the efficiency of translesion DNA synthesis. E S Szekeres, Roger Woodgate, Christopher W Lawrence Journal of bacteriology 1996 new
PCR fidelity of pfu DNA polymerase and other thermostable DNA polymerases. J Cline, J C Braman, Holly H Hogrefe Nucleic acids research 1996 partial results
DNA polymerase betas from liver and testes of cherry salmon, Oncorhynchus masou: purification and characterization of DNA polymerase betas with acidic isoelectric points. Tsuyoshi Yamaguchi, Susumu Nishimura, K Takahashi, M Yoshikuni, J Masaki, T Hirai, Mineo Saneyoshi J Biochem 1996 new
Analysis of mammalian recombination protein complex RC-1 Jessberger Rolf, Chui Gloria, Linn Stuart, Kemper Borries Mutation research 1996 pols set
Determination of the epitope of an inhibitory antibody to proliferating cell nuclear antigen. G Roos, Yanan Jiang, G Landberg, N H Nielsen, Peiming Zhang, Marietta Y W T Lee Experimental cell research 1996 new
[The radiobiologic characteristics of DNA polymerase beta in hepatomas]. J Cai, X Zheng, C Luo Zhonghua Zhong Liu Za Zhi 1996 new
Activation of replication origins in phi29-related phages requires the recognition of initiation proteins to specific nucleoprotein complexes. R Freire, M Serrano, Margarita Salas, José M Hermoso The Journal of biological chemistry 1996 pols set
Fidelity and error specificity of the alpha catalytic subunit of Escherichia coli DNA polymerase III. J Y Mo, Roel M Schaaper The Journal of biological chemistry 1996 partial results
An in vivo mutation from leucine to tryptophan at position 210 in human immunodeficiency virus type 1 reverse transcriptase contributes to high-level resistance to 3'-azido-3'-deoxythymidine. D J Hooker, G Tachedjian, A E Solomon, A D Gurusinghe, S Land, C Birch, J L Anderson, B M Roy, Edward Arnold, N J Deacon Journal of virology 1996 pols set
Human immunodeficiency virus type 1 drug susceptibility determination by using recombinant viruses generated from patient sera tested in a cell-killing assay. Charles A B Boucher, W Keulen, T van Bommel, Monique Nijhuis, D de Jong, M D de Jong, P Schipper, N K Back Antimicrob Agents Chemother 1996 new
Oligonucleotide inhibitors of Taq DNA polymerase facilitate detection of low copy number targets by PCR. C Dang, S D Jayasena Journal of molecular biology 1996 pols set
Marked inhibitory activity of non-nucleoside reverse transcriptase inhibitors against human immunodeficiency virus type 1 when combined with (-)2',3'-dideoxy-3'-thiacytidine. Jan Balzarini, H Pelemans, María-Jesús Pérez-Pérez, Ana San-Félix, María-José Camarasa, Erik De Clercq, Anna Karlsson Molecular pharmacology 1996 pols set
Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein. Y Kubota, R A Nash, A Klungland, P Schär, D E Barnes, T Lindahl The EMBO journal 1996 new
A 43 kDa DNA binding protein from the pea chloroplast interacts with and stimulates the cognate DNA polymerase. W Chen, A Gaikwad, Sunil K Mukherjee, N R Choudhary, Dinesh Kumar, K K Tewari Nucleic acids research 1996 new
Copy-choice recombination mediated by DNA polymerase III holoenzyme from Escherichia coli. D Canceill, S Dusko Ehrlich Proceedings of the National Academy of Sciences of the United States of America 1996 pols set
Novel L-lyxo and 5'-deoxy-5'-modified TSAO-T analogs: synthesis and anti-HIV-1 activity. S Ingate, Erik De Clercq, Jan Balzarini, María-José Camarasa Antiviral research 1996 pols set
Human immunodeficiency virus Type 1 nucleocapsid protein (NCp7) directs specific initiation of minus-strand DNA synthesis primed by human tRNA(Lys3) in vitro: studies of viral RNA molecules mutated in regions that flank the primer binding site. Xincang Li, Yudong Quan, E.J. Arts, Zhongjie Li, Bradley D Preston, H de Rocquigny, Bernard P Roques, J L Darlix, Lawrence Kleiman, Michael A. Parniak, Mark A. Wainberg Journal of virology 1996 pols set
Evidence for an imino intermediate in the DNA polymerase beta deoxyribose phosphate excision reaction. C E Piersen, Rajendra Prasad, Samuel H Wilson, R Stephen Lloyd The Journal of biological chemistry 1996 new
Processivity of the gene 41 DNA helicase at the bacteriophage T4 DNA replication fork. R D Schrock, B Alberts The Journal of biological chemistry 1996 partial results
Biochemical analysis of catalytically crucial aspartate mutants of human immunodeficiency virus type 1 reverse transcriptase. Neerja Kaushik, N Rege, P N Yadav, Stefan G Sarafianos, Mukund J Modak, V N Pandey Biochemistry 1996 pols set
Taq DNA polymerase blockage at pyrimidine dimers. R E Wellinger, F Thoma Nucleic acids research 1996 pols set
Zidovudine resistance is suppressed by mutations conferring resistance of human immunodeficiency virus type 1 to foscarnet. G Tachedjian, J Mellors, H Bazmi, C Birch, J Mills J Virol 1996 topics set
Use of chimeric human immunodeficiency virus types 1 and 2 reverse transcriptases for structure-function analysis and for mapping susceptibility to nonnucleoside inhibitors. G Yang, Q Song, M Charles, William C Drosopoulos, Edward Arnold, Vinayaka R Prasad Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1996 pols set
Role of methionine 184 of human immunodeficiency virus type-1 reverse transcriptase in the polymerase function and fidelity of DNA synthesis. V N Pandey, Neerja Kaushik, N Rege, Stefan G Sarafianos, P N Yadav, Mukund J Modak Biochemistry 1996 pols set
Cloning and characterization of the human mitochondrial DNA polymerase, DNA polymerase gamma. P A Ropp, William C Copeland Genomics 1996 new
Functional characterization of the genes coding for the terminal protein and DNA polymerase from bacteriophage GA-1. Evidence for a sliding-back mechanism during protein-primed GA-1 DNA replication. B Illana, Luis Blanco, Margarita Salas Journal of molecular biology 1996 pols set
Significance of amino acid variation at human immunodeficiency virus type 1 reverse transcriptase residue 210 for zidovudine susceptibility. P Richard Harrigan, I Kinghorn, Stuart Bloor, S D Kemp, I Nájera, A Kohli, Brendan A Larder J Virol 1996 topics set
Effects of modifying the tRNA(3Lys) anticodon on the initiation of human immunodeficiency virus type 1 reverse transcription. Yangxin Huang, A Shalom, Zhongjie Li, Jiong Wang, J Mak, Mark A. Wainberg, Lawrence Kleiman Journal of virology 1996 pols set
Expression, purification, and characterization of the herpes simplex virus type-1 DNA polymerase. Paul E Boehmer Methods in enzymology 1996 new
Characterization of the DNA polymerase requirement of human base excision repair. K Nealon, I D Nicholl, M K Kenny Nucleic acids research 1996 new
The terminal protein of the linear DNA plasmid pGKL2 shares an N-terminal domain of the plasmid-encoded DNA polymerase. M Takeda, H Hiraishi, T Takesako, S Tanase, N Gunge Yeast 1996 new
Structure of the UmuD' protein and its regulation in response to DNA damage. T S Peat, Ekaterina G Frank, John P McDonald, A S Levine, Roger Woodgate, W A Hendrickson Nature 1996 new
Studies of neutralizing monoclonal antibody to human immunodeficiency virus type 1 reverse transcriptase: antagonistic and synergistic effects in reactions performed in the presence of nucleoside and nonnucleoside inhibitors, respectively. Z Gu, Xincang Li, Yudong Quan, Michael A. Parniak, Mark A. Wainberg Journal of virology 1996 pols set
Rolling circle DNA replication by extracts of herpes simplex virus type 1-infected human cells. R Skaliter, Alexander M Makhov, Jack D Griffith, I. Robert Lehman Journal of virology 1996 new
Thermostable Bst DNA polymerase I lacks a 3'-->5' proofreading exonuclease activity. J M Aliotta, J J Pelletier, J L Ware, L S Moran, J S Benner, H Kong Genet Anal 1996 partial results
Purification and characterization of the catalytic subunit of human DNA polymerase delta expressed in baculovirus-infected insect cells. Jin-Qiu Zhou, Cheng-Keat Tan, Antero G So, Kathleen M Downey The Journal of biological chemistry 1996 pols set
DNA polymerase beta gene mutations in human bladder cancer. J Matsuzaki, Y Dobashi, H Miyamoto, I Ikeda, K Fujinami, T Shuin, Y Kubota Mol Carcinog 1996 pols set
Construction by homologous recombination and phenotypic characterization of a DNA polymerase domain polA mutant of Mycobacterium smegmatis. B G Gordhan, S J Andersen, A R De Meyer, V Mizrahi Gene 1996 new
Therapeutic potential of Cidofovir (HPMPC, Vistide) for the treatment of DNA virus (i.e. herpes-, papova-, pox- and adenovirus) infections. Erik De Clercq Verhandelingen - Koninklijke Academie voor Geneeskunde van België 1996 new
DNA end joining by the Klenow fragment of DNA polymerase I. J S King, C F Fairley, W F Morgan The Journal of biological chemistry 1996 pols set
Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. H Pelletier, M R Sawaya Biochemistry 1996 topics set
Relating structure to function in phi29 DNA polymerase. Luis Blanco, Margarita Salas The Journal of biological chemistry 1996 pols set
Development of vaginal microbicides for the prevention of heterosexual transmission of HIV. Rudi Pauwels, Erik De Clercq Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1996 pols set
Betulinic acid derivatives: a new class of specific inhibitors of human immunodeficiency virus type 1 entry. F Soler, C Poujade, M Evers, J C Carry, Y Hénin, Anne Bousseau, T Huet, Rudi Pauwels, Erik De Clercq, J F Mayaux, J B Le Pecq, N Dereu Journal of medicinal chemistry 1996 pols set
Antiviral activity of the bicyclam derivative JM3100 against drug-resistant strains of human immunodeficiency virus type 1. J A Esté, K De Vreese, Myriam Witvrouw, J C Schmit, A-M Vandamme, J Anné, J Desmyter, G W Henson, G Bridger, Erik De Clercq Antiviral research 1996 pols set
What can be Expected from Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs) in the Treatment of Human Immunodeficiency Virus Type 1 (HIV-1) Infections? De Clercq E Reviews in medical virology 1996 new
Measurement of human cytomegalovirus-associated DNA polymerase activity in patient urine as a potential diagnostic tool. A Marcello, G Pisoni, S Pizzighella, Giorgio Palù Intervirology 1996 pols set
Domain organization and DNA-induced conformational changes of an archaeal family B DNA polymerase. Francesca M Pisani, G Manco, V Carratore, Mosè Rossi Biochemistry 1996 new
DNA polymerase photoprobe 2-[(4-azidophenacyl)thio]-2'-deoxyadenosine 5'-triphosphate labels an Escherichia coli DNA polymerase I Klenow fragment substrate binding site. B M Moore, R K Jalluri, Michael B Doughty Biochemistry 1996 pols set
Fluorometric assay for DNA polymerases and reverse transcriptase. M Seville, A B West, M G Cull, Charles S McHenry BioTechniques 1996 pols set
Biotin tagging deletion analysis of domain limits involved in protein-macromolecular interactions. Mapping the tau binding domain of the DNA polymerase III alpha subunit. D R Kim, Charles S McHenry The Journal of biological chemistry 1996 new
Fatty acids selectively inhibit eukaryotic DNA polymerase activities in vitro. Yoshiyuki Mizushina, Naotaka Tanaka, Haruhiko Yagi, T Kurosawa, M Onoue, H Seto, T Horie, N Aoyagi, M Yamaoka, Akio Matsukage, Shonen Yoshida, Kengo Sakaguchi Biochimica et biophysica acta 1996 new
New arylpyrido-diazepine and -thiodiazepine derivatives are potent and highly selective HIV-1 inhibitors targeted at the reverse transcriptase. D Bellarosa, G Antonelli, F Bambacioni, D Giannotti, G Viti, R Nannicini, A Giachetti, F Dianzani, Myriam Witvrouw, Rudi Pauwels, J Desmyter, Erik De Clercq Antiviral research 1996 pols set
In vitro reconstitution of human replication factor C from its five subunits. F Uhlmann, J Cai, H Flores-Rozas, F B Dean, Jeff Finkelstein, Mike E O'Donnell, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1996 new
Thymine-thymine dimer bypass by yeast DNA polymerase zeta. John R Nelson, Christopher W Lawrence, David C Hinkle Science 1996 new
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) for the treatment of human immunodeficiency virus type 1 (HIV-1) infections: strategies to overcome drug resistance development. Erik De Clercq Medicinal research reviews 1996 new
Comparative kinetic analyses of interaction of inhibitors with Rauscher murine leukemia virus and human immunodeficiency virus reverse transcriptases. J M Cherrington, M D Fuller, A S Mulato, S J Allen, S C Kunder, M A Ussery, Z Lesnikowski, Raymond F Schinazi, J P Sommadossi, M S Chen Antimicrob Agents Chemother 1996 new
Catalytic subunit of mitochondrial DNA polymerase from Drosophila embryos. Cloning, bacterial overexpression, and biochemical characterization. D L Lewis, Carol L Farr, Yazhen Wang, Anthony T Lagina, Laurie S Kaguni The Journal of biological chemistry 1996 new
Replication protein-A mediates the association of calf thymus DNA polymerase alpha-DNA primase complex with guanine-rich DNA sequence. Motoshi Suzuki, K Tamiya-Koizumi, Masaharu Takemura, Kyoji Furuta, Shunji Izuta, E Savoysky, A Miura, Shonen Yoshida Journal of biochemistry 1996 new
The carboxyl terminus of the bacteriophage T4 DNA polymerase is required for holoenzyme complex formation. Anthony J Berdis, P Soumillion, Stephen J Benkovic Proceedings of the National Academy of Sciences of the United States of America 1996 topics set
Faulty DNA polymerase delta/epsilon-mediated excision repair in response to gamma radiation or ultraviolet light in p53-deficient fibroblast strains from affected members of a cancer-prone family with Li-Fraumeni syndrome. R Mirzayans, L Enns, K Dietrich, R D Barley, M C Paterson Carcinogenesis 1996 new
Base analog 6-N-hydroxylaminopurine mutagenesis in the yeast Saccharomyces cerevisiae is controlled by replicative DNA polymerases. Polina V Shcherbakova, V N Noskov, M R Pshenichnov, Youri I Pavlov Mutation research 1996 topics set
Effects of 3'-deoxynucleoside 5'-triphosphate concentrations on chain termination by nucleoside analogs during human immunodeficiency virus type 1 reverse transcription of minus-strand strong-stop DNA. E.J. Arts, J P Marois, Z Gu, Stuart F J Le Grice, Mark A. Wainberg Journal of virology 1996 pols set
In vitro bypass replication of the cisplatin-d(GpG) lesion by calf thymus DNA polymerase beta and human immunodeficiency virus type I reverse transcriptase is highly mutagenic. Jean-Sébastien Hoffmann, Marie-Jeanne Pillaire, D Garcia-Estefania, S Lapalu, Giuseppe Villani The Journal of biological chemistry 1996 new
Identification of a DinB/UmuC homolog in the archeon Sulfolobus solfataricus. O I Kulaeva, Eugene V Koonin, John P McDonald, S K Randall, N Rabinovich, J F Connaughton, A S Levine, Roger Woodgate Mutation research 1996 pols set
Proliferating cell nuclear antigen promotes misincorporation catalyzed by calf thymus DNA polymerase delta. Dmitry Ju Mozzherin, Maeve McConnell, M V Jasko, A A Krayevsky, Cheng-Keat Tan, Kathleen M Downey, Paul A Fisher The Journal of biological chemistry 1996 topics set
Human DNA polymerase epsilon: enzymologic mechanism and gap-filling synthesis. Dmitry Ju Mozzherin, Paul A Fisher Biochemistry 1996 pols set
Characterization of fluorescent nucleoside triphosphates by capillary electrophoresis with laser-induced fluorescence detection: action of alkaline phosphatase and DNA polymerase. R A Evangelista, M S Liu, S Rampal, F T Chen Anal Biochem 1996 new
DNA polymerases from a parasitic protozoa Leishmania donovani UR6: evidence of presence of a novel kind of DNA polymerase. S Sen, N V Khalkho, H K Majumder Biochem Biophys Res Commun 1996 new
Mechanism of polyoxometalate-mediated inactivation of DNA polymerases: an analysis with HIV-1 reverse transcriptase indicates specificity for the DNA-binding cleft. Stefan G Sarafianos, U Kortz, M T Pope, Mukund J Modak Biochem J 1996 new
DNA polymerase activity of hepatitis B virus particles: differential inhibition by L-enantiomers of nucleotide analogs. M G Davis, J E Wilson, N A VanDraanen, W H Miller, George A Freeman, S M Daluge, F L Boyd, A E Aulabaugh, George R Painter, Lawrence R Boone Antiviral Res 1996 new
Replication of O6-methylguanine-containing DNA by repair and replicative DNA polymerases. Linda J Reha-Krantz, R L Nonay, R S Day, Samuel H Wilson The Journal of biological chemistry 1996 complete
Isolation of mammalian pol beta type DNA polymerase in shoot tips of germinated seedlings of IR-8 rice (Oryza sativa L.). M Sanathkumar, B Ghosh, Dibyendu Narayan SenGupta Biochem Mol Biol Int 1996 new
Prostate-specific antigen promoter driven gene therapy targeting DNA polymerase-alpha and topoisomerase II alpha in prostate cancer. C H Lee, Meiquing Liu, K L Sie, M S Lee Anticancer Res 1996 new
Inhibition of DNA polymerase alpha expression and cell growth, a possible triple helix mechanism. A Alama, F Barbieri, M Cagnoli, M Mazzei, T Grandi, A Nicolin Antisense Nucleic Acid Drug Dev 1996 new
The UmuD' protein filament and its potential role in damage induced mutagenesis. T S Peat, Ekaterina G Frank, John P McDonald, A S Levine, Roger Woodgate, W A Hendrickson Structure (London, England : 1993) 1996 new
NMR study of the conformation of the 2-aminopurine:cytosine mismatch in DNA. P A Fagan, C Fàbrega, R Eritja, Myron F Goodman, D E Wemmer Biochemistry 1996 new
DNA polymerase beta: pre-steady-state kinetic analysis and roles of arginine-283 in catalysis and fidelity. B G Werneburg, J Ahn, Xuejun Zhong, R J Hondal, V S Kraynov, Ming-Daw Tsai Biochemistry 1996 new
Phosphorylation of the DNA polymerase alpha-primase B subunit is dependent on its association with the p180 polypeptide. M Ferrari, G Lucchini, Paolo Plevani, Marco Foiani The Journal of biological chemistry 1996 new
Increased polymerase fidelity of E89G, a nucleoside analog-resistant variant of human immunodeficiency virus type 1 reverse transcriptase. William C Drosopoulos, Vinayaka R Prasad J Virol 1996 topics set
The K65R mutation confers increased DNA polymerase processivity to HIV-1 reverse transcriptase. Dominique Arion, G Borkow, Z Gu, Mark A. Wainberg, Michael A. Parniak The Journal of biological chemistry 1996 partial results
Deoxy- and dideoxynucleotide discrimination and identification of critical 5' nuclease domain residues of the DNA polymerase I from Mycobacterium tuberculosis. V Mizrahi, P Huberts Nucleic acids research 1996 pols set
Transcription-positive cofactor 4 forms complexes with HSSB (RPA) on single-stranded DNA and influences HSSB-dependent enzymatic synthesis of simian virus 40 DNA. Z Q Pan, H Ge, A A Amin, Jerard Hurwitz The Journal of biological chemistry 1996 new
Role of the "helix clamp" in HIV-1 reverse transcriptase catalytic cycling as revealed by alanine-scanning mutagenesis. William A Beard, Dana T Minnick, C L Wade, Rajendra Prasad, R L Won, A Kumar, Thomas A Kunkel, Samuel H Wilson The Journal of biological chemistry 1996 pols set
Functional consequences and exonuclease kinetic parameters of point mutations in bacteriophage T4 DNA polymerase. A K Abdus Sattar, T C Lin, C Jones, William H Konigsberg Biochemistry 1996 complete
Chemotherapy of human immunodeficiency virus (HIV) infection: anti-HIV agents targeted at early stages in the virus replicative cycle. Erik De Clercq Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 1996 pols set
The association between cell proliferation and apoptosis: studies using the cell cycle-associated proteins Ki67 and DNA polymerase alpha. P J Coates, S A Hales, P A Hall J Pathol 1996 new
Application of N-terminally truncated DNA polymerase from Thermus thermophilus (delta Tth polymerase) to DNA sequencing and polymerase chain reactions: comparative study of delta Tth and wild-type Tth polymerases. T Arakawa, B Jongsareejit, Y Tatsumi, K Tanaka, Kyoji Ikeda, H Komatsubara, Hirokazu Inoue, B Kawakami, M Oka, S Emi, Tetsuya Yomo, Yasufumi Shima, S Negoro, Itaru Urabe DNA Res 1996 new
The nucleoside analog-resistant E89G mutant of human immunodeficiency virus type 1 reverse transcriptase displays a broader cross-resistance that extends to nonnucleoside inhibitors. Y Kew, H Salomon, L R Olsen, Mark A. Wainberg, Vinayaka R Prasad Antimicrobial agents and chemotherapy 1996 new
Dominant negative rat DNA polymerase beta mutants interfere with base excision repair in Saccharomyces cerevisiae. C A Clairmont, Joann B Sweasy J Bacteriol 1996 new
Betulinic acid derivatives: a new class of human immunodeficiency virus type 1 specific inhibitors with a new mode of action. M Evers, C Poujade, F Soler, Y Ribeill, C James, Y Lelièvre, J C Gueguen, D Reisdorf, I Morize, Rudi Pauwels, Erik De Clercq, Y Hénin, Anne Bousseau, J F Mayaux, J B Le Pecq, N Dereu Journal of medicinal chemistry 1996 pols set
Efficacy of triple combination therapy with zidovudine (ZDV) plus zalcitabine (ddC) plus lamivudine (3TC) versus double (ZDV+3TC) combination therapy in patients previously treated with ZDV+ddC. L Ruiz, J Romeu, J Martínez-Picado, J C Schmit, Anne-Mieke Vandamme, M Balagué, C Cabrera, T Puig, C Tural, A Segura, G Sirera, Erik De Clercq, B Clotet AIDS (London, England) 1996 new
Three-dimensional solution structure of the N-terminal domain of DNA polymerase beta and mapping of the ssDNA interaction interface. D Liu, Rajendra Prasad, Samuel H Wilson, Eugene F DeRose, Gregory P Mullen Biochemistry 1996 topics set
Requirement of proliferating cell nuclear antigen in RAD6-dependent postreplicational DNA repair. Carlos A Torres-Ramos, B L Yoder, Peter M J Burgers, Satya Prakash, Louise Prakash Proceedings of the National Academy of Sciences of the United States of America 1996 new
A coupled complex of T4 DNA replication helicase (gp41) and polymerase (gp43) can perform rapid and processive DNA strand-displacement synthesis. F Dong, S E Weitzel, Peter H von Hippel Proceedings of the National Academy of Sciences of the United States of America 1996 complete
HIV-1 reverse transcriptase shows no specificity for the binding of primer tRNA(Lys3). Dominique Arion, R Harada, Xincang Li, Mark A. Wainberg, Michael A. Parniak Biochemical and biophysical research communications 1996 pols set
Cycle sequencing protocol using deep VentR (exo-) DNA polymerase and reduced dNTP and [alpha-35S]dATP concentrations. B Mariamé BioTechniques 1996 new
Termination within oligo(dT) tracts in template DNA by DNA polymerase gamma occurs with formation of a DNA triplex structure and is relieved by mitochondrial single-stranded DNA-binding protein. V S Mikhailov, Daniel F Bogenhagen The Journal of biological chemistry 1996 pols set
Evaluation of the efficacy and tolerance of R 018893, R 089439 (loviride) and placebo in asymptomatic HIV-1-infected patients. Loviride Collaborative Study Group. Schlomo Staszewski, V Miller, A Kober, R Colebunders, B Vandercam, J Delescluse, N Clumeck, F Van Wanzeele, M De Brabander, J De Creé, M Moeremans, Koen Andries, C Boucher, Paul Stoffels, Paul A J Janssen Antiviral therapy 1996 pols set
HIV-1 reverse transcriptase resistance to nonnucleoside inhibitors. R A Spence, Karen S Anderson, Kenneth A Johnson Biochemistry 1996 topics set
In vitro selection and molecular characterization of human immunodeficiency virus type 1 with reduced sensitivity to 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA). A Foli, K M Sogocio, B Anderson, M Kavlick, M W Saville, Mark A. Wainberg, Z Gu, J M Cherrington, Hiroyuki Mitsuya, R Yarchoan Antiviral research 1996 pols set
Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase. Mark A. Wainberg, William C Drosopoulos, H Salomon, M Hsu, G Borkow, M Parniak, Z Gu, Q Song, J Manne, S Islam, G Castriota, Vinayaka R Prasad Science (New York, N.Y.) 1996 pols set
Analysis and suppression of DNA polymerase pauses associated with a trinucleotide consensus. D S Mytelka, M J Chamberlin Nucleic acids research 1996 new
Selection conditions affect the evolution of specific mutations in the reverse transcriptase gene associated with resistance to DMP 266. D L Winslow, S Garber, C Reid, H Scarnati, D Baker, M M Rayner, E D Anton AIDS (London, England) 1996 pols set
Beta*, a UV-inducible smaller form of the beta subunit sliding clamp of DNA polymerase III of Escherichia coli. I. Gene expression and regulation. T Paz-Elizur, R Skaliter, S Blumenstein, Zvi Livneh The Journal of biological chemistry 1996 pols set
In vivo assembly of the tau-complex of the DNA polymerase III holoenzyme expressed from a five-gene artificial operon. Cleavage of the tau-complex to form a mixed gamma-tau-complex by the OmpT protease. Arthur E Pritchard, H Garry Dallmann, Charles S McHenry The Journal of biological chemistry 1996 new
Kinetic analysis of the interaction of cidofovir diphosphate with human cytomegalovirus DNA polymerase. Xiwen Xiong, J L Smith, C Kim, E S Huang, M S Chen Biochem Pharmacol 1996 pols set
Specific interaction of DNA polymerase beta and DNA ligase I in a multiprotein base excision repair complex from bovine testis. Rajendra Prasad, R K Singhal, Deepak K Srivastava, J T Molina, Alan E Tomkinson, Samuel H Wilson The Journal of biological chemistry 1996 new
Thermostable DNA polymerases. F B Perler, Sandeep Kumar, H Kong Adv Protein Chem 1996 partial results
Isolation and characterization of cDNA for DREF, a promoter-activating factor for Drosophila DNA replication-related genes. Fumiko Hirose, Masamitsu Yamaguchi, Kazufumi Kuroda, A Omori, T Hachiya, M Ikeda, Y Nishimoto, Akio Matsukage The Journal of biological chemistry 1996 new
Cloning of thermostable DNA polymerases from hyperthermophilic marine Archaea with emphasis on Thermococcus sp. 9 degrees N-7 and mutations affecting 3'-5' exonuclease activity. M W Southworth, H Kong, R B Kucera, J Ware, H W Jannasch, F B Perler Proceedings of the National Academy of Sciences of the United States of America 1996 partial results
In vitro expansion of GGC:GCC repeats: identification of the preferred strand of expansion. J Ji, N J Clegg, K R Peterson, A L Jackson, C D Laird, Lawrence A Loeb Nucleic acids research 1996 pols set
Construction of single amino acid substitution mutants of cloned Bacillus stearothermophilus DNA polymerase I which lack 5'-->3' exonuclease activity. M G Riggs, S Tudor, M Sivaram, S H McDonough Biochimica et biophysica acta 1996 pols set
Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors. Andrew L Hopkins, Jingshan Ren, R M Esnouf, B E Willcox, E Yvonne Jones, C Ross, T Miyasaka, R T Walker, Hiromichi Tanaka, David K Stammers, David I Stuart J Med Chem 1996 topics set
Amplification, cloning, and sequence comparison of the growth hormone gene for carp (Cyprinus carpio) by the polymerase chain reaction. Xu Zhao, Jinming Li, Rong Li, Shuren Zhang, Yong Zhang, Zhengan Yang Chinese journal of biotechnology 1996 pols set
Inhibition of hepatitis B virus DNA polymerase by enantiomers of penciclovir triphosphate and metabolic basis for selective inhibition of HBV replication by penciclovir. T Shaw, S S Mok, S A Locarnini Hepatology 1996 topics set
DNA polymerase III: running rings around the fork. D R Herendeen, T J Kelly Cell 1996 new
Schizosaccharomyces pombe proliferating cell nuclear antigen mutations affect DNA polymerase delta processivity. M P Arroyo, Kathleen M Downey, Antero G So, Teresa S-F Wang The Journal of biological chemistry 1996 new
The gamma subfamily of DNA polymerases: cloning of a developmentally regulated cDNA encoding Xenopus laevis mitochondrial DNA polymerase gamma. F Ye, José A Carrodeguas, Daniel F Bogenhagen Nucleic acids research 1996 pols set
Reducing "double sequences" in automated DNA sequencing with T7 DNA polymerase and internal labeling. S Wiemann, A Schilke, S Rechmann, J Zimmermann, H Voss, W Ansorge BioTechniques 1996 pols set
Endogenous reverse transcription assays reveal high-level resistance to the triphosphate of (-)2'-dideoxy-3'-thiacytidine by mutated M184V human immunodeficiency virus type 1. Yudong Quan, Z Gu, Xincang Li, Zhongjie Li, C D Morrow, Mark A. Wainberg J Virol 1996 topics set
DNA replication-related elements cooperate to enhance promoter activity of the drosophila DNA polymerase alpha 73-kDa subunit gene. Y Takahashi, Masamitsu Yamaguchi, Fumiko Hirose, Sue Cotterill, Jun'ichi Kobayashi, S Miyajima, Akio Matsukage The Journal of biological chemistry 1996 new
Pyridoxal 5'-phosphate inhibition of adenovirus DNA polymerase. A Monaghan, R T Hay The Journal of biological chemistry 1996 new
Enzyme-DNA interactions required for efficient nucleotide incorporation and discrimination in human DNA polymerase beta. William A Beard, Wendy P Osheroff, Rajendra Prasad, M R Sawaya, M Jaju, T G Wood, J Kraut, Thomas A Kunkel, Samuel H Wilson The Journal of biological chemistry 1996 topics set
Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme. N K Back, Monique Nijhuis, W Keulen, Charles A B Boucher, B O Oude Essink, A B van Kuilenburg, A H van Gennip, Ben Berkhout The EMBO journal 1996 topics set
Novel mutation (K70E) in human immunodeficiency virus type 1 reverse transcriptase confers decreased susceptibility to 9-[2-(phosphonomethoxy)ethyl]adenine in vitro. J M Cherrington, A S Mulato, M D Fuller, M S Chen Antimicrobial agents and chemotherapy 1996 pols set
Mitochondrial DNA polymerase gamma is expressed and translated in the absence of mitochondrial DNA maintenance and replication. A F Davis, P A Ropp, D A Clayton, William C Copeland Nucleic acids research 1996 new
Purification and characterization of a DNA polymerase beta promoter initiator element-binding transcription factor from bovine testis. Feng He, Satya Narayan, Samuel H Wilson Biochemistry 1996 new
Effects of Xenopus laevis mitochondrial single-stranded DNA-binding protein on primer-template binding and 3'-->5' exonuclease activity of DNA polymerase gamma. V S Mikhailov, Daniel F Bogenhagen The Journal of biological chemistry 1996 new
Anti-HIV and anti-HBV activity and resistance profile of 2',3'-dideoxy-3'-thiacytidine (3TC) and its arylphosphoramidate derivative CF 1109. Jan Balzarini, O Wedgwood, J Kruining, H Pelemans, R Heijtink, Erik De Clercq, Christopher McGuigan Biochemical and biophysical research communications 1996 pols set
Heterologous expression, purification, and characterization of adenovirus DNA polymerase and preterminal protein. M Ramachandra, Y Sasaguri, R Nakano, R Padmanabhan Methods in enzymology 1996 new
A two plasmid co-expression system in Escherichia coli for the production of virion-like reverse transcriptase of the human immunodeficiency virus type 1. H Jonckheere, K De Vreese, Zeger Debyser, J Vandekerckhove, Jan Balzarini, J Desmyter, Erik De Clercq, J Anné Journal of virological methods 1996 pols set
Peptide rescue of an N-terminal truncation of the Stoffel fragment of taq DNA polymerase. I Vainshtein, A Atrazhev, Soo Hyun Eom, J F Elliott, D S Wishart, B A Malcolm Protein science : a publication of the Protein Society 1996 pols set
Amino acid residues critical for the interaction between bacteriophage T7 DNA polymerase and Escherichia coli thioredoxin. J S Himawan, Charles C Richardson The Journal of biological chemistry 1996 pols set
Progress towards DNA sequencing at the single molecule level Experimental Technique of Physics 1996 topics set
Exonucleolytic proofreading during replication of repetitive DNA. L C Kroutil, K Register, Katarzyna Bebenek, Thomas A Kunkel Biochemistry 1996 new
DNA replication machinery: functional characterization of a complex containing DNA polymerase alpha, DNA polymerase delta, and replication factor C suggests an asymmetric DNA polymerase dimer. Giovanni Maga, Ulrich Hübscher Biochemistry 1996 new
Chromium(VI) treatment of normal human lung cells results in guanine-specific DNA polymerase arrest, DNA-DNA cross-links and S-phase blockade of cell cycle. J Xu, G J Bubley, B Detrick, L J Blankenship, Steven R Patierno Carcinogenesis 1996 new
Slow rate of phosphodiester bond formation accounts for the strong bias that Taq DNA polymerase shows against 2',3'-dideoxynucleotide terminators. J W Brandis, S G Edwards, Kenneth A Johnson Biochemistry 1996 topics set
Identification of novel mRNA isoforms for human DNA polymerase beta. Yau-Jan Chyan, Phyllis R Strauss, T G Wood, Samuel H Wilson DNA Cell Biol 1996 pols set
Epstein-Barr virus single-stranded DNA-binding protein: purification, characterization, and action on DNA synthesis by the viral DNA polymerase. Tatsuya Tsurumi, Atsushi Kobayashi, Katsuyuki Tamai, H Yamada, T Daikoku, Y Yamashita, Yoshitaka Nishiyama Virology 1996 pols set
Inhibition of the 3' --> 5' exonuclease of human DNA polymerase epsilon by fludarabine-terminated DNA. Kenji Kamiya, P Huang, W Plunkett The Journal of biological chemistry 1996 pols set
Reconstitution of human replication factor C from its five subunits in baculovirus-infected insect cells. J Cai, F Uhlmann, E Gibbs, H Flores-Rozas, C G Lee, B Phillips, Jeff Finkelstein, N Yao, Mike E O'Donnell, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1996 new
In vivo assembly of overproduced DNA polymerase III. Overproduction, purification, and characterization of the alpha, alpha-epsilon, and alpha-epsilon-theta subunits. D R Kim, Charles S McHenry The Journal of biological chemistry 1996 new
DNA polymerase delta-dependent formation of a hairpin structure at the 5' terminal palindrome of the minute virus of mice genome. N Cossons, E A Faust, M Zannis-Hadjopoulos Virology 1996 new
Roles of multiple promoter elements of the proliferating cell nuclear antigen gene during Drosophila development. Masamitsu Yamaguchi, Fumiko Hirose, Akio Matsukage Genes to cells : devoted to molecular & cellular mechanisms 1996 new
Kinetic mechanism of the 3'-->5' proofreading exonuclease of DNA polymerase III. Analysis by steady state and pre-steady state methods. Holly Miller, Fred W Perrino Biochemistry 1996 new
[Isolation of catalytically active subunit of protein kinase from a complex form of DNA-polymerase alpha in the rat liver using electrofractionation in denaturing conditions]. S N Naryzhnyĭ Mol Biol (Mosk) 1996 new
Potential role of DNA polymerase beta in gene therapy against cancer: a case for colorectal cancer. F F Shadan, L P Villarreal Med Hypotheses 1996 new
Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA. Jacqueline M Gulbis, Zvi Kelman, Jerard Hurwitz, Mike E O'Donnell, John Kuriyan Cell 1996 pols set
Elucidation of the role of Arg 110 of murine leukemia virus reverse transcriptase in the catalytic mechanism: biochemical characterization of its mutant enzymes. K Chowdhury, Neerja Kaushik, V N Pandey, Mukund J Modak Biochemistry 1996 new
Deoxyadenosine-based DNA polymerase photoprobes: design, synthesis, and characterization as inhibitors of the Escherichia coli DNA polymerase I Klenow fragment. B M Moore, Ke Li, Michael B Doughty Biochemistry 1996 pols set
DNA polymerase beta belongs to an ancient nucleotidyltransferase superfamily. L Holm, C Sander Trends in biochemical sciences 1995 new
Antiviral activity and protection of cells against human immunodeficiency virus type-1 using an antisense oligodeoxyribonucleotide phosphorothioate complementary to the 5'-LTR region of the viral genome. M I Anazodo, H Salomon, A D Friesen, Mark A. Wainberg, J A Wright Gene 1995 pols set
Rapid quench kinetic analysis of polymerases, adenosinetriphosphatases, and enzyme intermediates. Kenneth A Johnson Methods in enzymology 1995 new
Effects of non-nucleoside inhibitors of human immunodeficiency virus type 1 in cell-free recombinant reverse transcriptase assays. Z Gu, Yudong Quan, Zhongjie Li, E.J. Arts, Mark A. Wainberg The Journal of biological chemistry 1995 pols set
Mutations within conserved motifs in the 3'-5' exonuclease domain of herpes simplex virus DNA polymerase. J D Hall, K L Orth, K L Sander, B M Swihart, R A Senese The Journal of general virology 1995 new
Primer terminus stabilization at the phi 29 DNA polymerase active site. Mutational analysis of conserved motif KXY. M A Blasco, Juan Méndez, José María Lázaro, Luis Blanco, Margarita Salas The Journal of biological chemistry 1995 pols set
A non-alpha-like DNA polymerase from the hyperthermophilic archaeon Pyrococcus furiosus. M Imamura, Takashi Uemori, Ikunoshin Kato, Yoshizumi Ishino Biol Pharm Bull 1995 new
Synergistic inhibition of HIV-1 reverse transcriptase DNA polymerase activity and virus replication in vitro by combinations of carboxanilide nonnucleoside compounds. Ronald S Fletcher, Dominique Arion, G Borkow, Mark A. Wainberg, G I Dmitrienko, Michael A. Parniak Biochemistry 1995 pols set
Sequence-specific inhibition of gene expression by a novel antisense oligodeoxynucleotide phosphorothioate directed against a nonregulatory region of the human immunodeficiency virus type 1 genome. M I Anazodo, Mark A. Wainberg, A D Friesen, J A Wright Journal of virology 1995 pols set
Release of the hepatitis B virus-associated DNA polymerase from the viral particle by the proteolytic cleavage. H J Shin, H M Rho The Journal of biological chemistry 1995 new
A mutant T7 RNA polymerase as a DNA polymerase. R Sousa, R Padilla The EMBO journal 1995 new
Mammalian DNA polymerase auxiliary proteins: analysis of replication factor C-catalyzed proliferating cell nuclear antigen loading onto circular double-stranded DNA. L M Podust, Vladimir N Podust, J M Sogo, Ulrich Hübscher Molecular and cellular biology 1995 pols set
Molecular modeling studies of HIV-1 reverse transcriptase nonnucleoside inhibitors: total energy of complexation as a predictor of drug placement and activity. Marilyn B Kroeger Smith, C A Rouzer, L A Taneyhill, N A Smith, Stephen H Hughes, Paul L Boyer, Paul A J Janssen, H Moereels, Luc Koymans, Edward Arnold Protein science : a publication of the Protein Society 1995 pols set
Mutational analysis of bacteriophage phi 29 DNA polymerase. Luis Blanco, Margarita Salas Methods in enzymology 1995 pols set
A nucleotide sequence essential for the function of DRE, a common promoter element for Drosophila DNa replication-related genes. Masamitsu Yamaguchi, Y Hayashi, Y Nishimoto, Fumiko Hirose, Akio Matsukage The Journal of biological chemistry 1995 new
Temperature-sensitive mutation of DNA polymerase alpha induces growth-suppressive phenotypes involving retinoblastoma protein and cyclin D1. K Yamaguchi, M Kobayashi, Y Yamauchi, Akira Tanaka, Hiroshi Miyazawa, M Izumi, Fumio Hanaoka Cell Struct Funct 1995 new
Isolation and characterization of inhibitory factors of DNA polymerase III holoenzyme from Escherichia coli. M Hase, T Mizushima, T Katayama, K Sekimizu FEMS Microbiol Lett 1995 pols set
Specific inhibition of DNA polymerase beta by its 14 kDa domain: role of single- and double-stranded DNA binding and 5'-phosphate recognition. I Husain, B S Morton, William A Beard, R K Singhal, Rajendra Prasad, Samuel H Wilson, J M Besterman Nucleic acids research 1995 new
Studies of Schizosaccharomyces pombe DNA polymerase alpha at different stages of the cell cycle. H Park, R Davis, Teresa S-F Wang Nucleic acids research 1995 new
Sequence and transcriptional analysis of the guinea-pig cytomegalovirus DNA polymerase gene. M R Schleiss The Journal of general virology 1995 new
Template-switching during DNA synthesis by Thermus aquaticus DNA polymerase I. S J Odelberg, R B Weiss, A Hata, R White Nucleic acids research 1995 pols set
Purification and characterization of a beta-like DNA polymerase from Trypanosoma cruzi. J Venegas, A Solari Mol Biochem Parasitol 1995 pols set
Bovine papillomavirus E1 protein binds specifically DNA polymerase alpha but not replication protein A. C Bonne-Andrea, S Santucci, P Clertant, F Tillier J Virol 1995 new
Purification and properties of wild-type and exonuclease-deficient DNA polymerase II from Escherichia coli. H Cai, Hong Yu, K McEntee, Thomas A Kunkel, Myron F Goodman The Journal of biological chemistry 1995 pols set
DNA polymerase from Saccharomyces cerevisiae. Peter M J Burgers Methods in enzymology 1995 new
An increased DNA polymerase activity associated with virulence of Toxoplasma gondii. A Makioka, H Ohtomo J Parasitol 1995 pols set
Nucleotide excision repair DNA synthesis by DNA polymerase epsilon in the presence of PCNA, RFC, and RPA. M K Shivji, Vladimir N Podust, Ulrich Hübscher, Richard D Wood Biochemistry 1995 new
Carboxanilide derivative non-nucleoside inhibitors of HIV-1 reverse transcriptase interact with different mechanistic forms of the enzyme. Ronald S Fletcher, K Syed, S Mithani, G I Dmitrienko, Michael A. Parniak Biochemistry 1995 pols set
Assignment of the 36.5-kDa (RFC5), 37-kDa (RFC4), 38-kDa (RFC3), and 40-kDa (RFC2) subunit genes of human replication factor C to chromosome bands 12q24.2-q24.3, 3q27, 13q12.3-q13, and 7q11.23. K Okumura, M Nogami, H Taguchi, F B Dean, M Chen, Z Q Pan, Jerard Hurwitz, A Shiratori, Y Murakami, Kiyoshi Ozawa Genomics 1995 new
The N-terminus of fission yeast DNA polymerase alpha contains a basic pentapeptide that acts in vivo as a nuclear localization signal. D Bouvier, Giuseppe Baldacci Mol Biol Cell 1995 new
Isolation and sequence determination of the cDNA encoding DNA polymerase delta from Drosophila melanogaster. C S Chiang, I. Robert Lehman Gene 1995 pols set
Sensitivity of the DNA polymerase activities of Tetrahymena pyriformis to cytosine arabinoside triphosphate and N-ethyl-maleiimide. M A Benhura Pharmazie 1995 new
Purification of DNA polymerase-primase (DNA polymerase alpha) and DNA polymerase delta from embryos of Drosophila melanogaster. P G Mitsis, C S Chiang, I. Robert Lehman Methods in enzymology 1995 new
Cycling of Escherichia coli DNA polymerase III from one sliding clamp to another: model for lagging strand. J Turner, Mike E O'Donnell Methods in enzymology 1995 pols set
Activity of various thiocarboxanilide derivatives against wild-type and several mutant human immunodeficiency virus type 1 strains. Jan Balzarini, W G Brouwer, E E Felauer, Erik De Clercq, Anna Karlsson Antiviral research 1995 pols set
DNA polymerase III holoenzyme: structure and function of a chromosomal replicating machine. Zvi Kelman, Mike E O'Donnell Annu Rev Biochem 1995 new
Knocking out human immunodeficiency virus through non-nucleoside reverse transcriptase inhibitors used as single agents or in combinations: a paradigm for the cure of AIDS? Erik De Clercq, Jan Balzarini Farmaco (Società chimica italiana : 1989) 1995 pols set
Position 26 of the first domain of the HLA-DQB1 allele in post-silicone implant scleroderma. J H Morse, M Fotino, Yang Zhang, E R Flaster, C L Peebles, H Spiera The Journal of rheumatology 1995 new
The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: lessons for inhibitor design. Jingshan Ren, R Esnouf, A Hopkins, C Ross, Y Jones, D Stammers, David I Stuart Structure (London, England : 1993) 1995 topics set
Characterisation of a gain-of-function mutant of poly(ADP-ribose) polymerase. E A Miranda, F Dantzer, M O'Farrell, Gilbert de Murcia, J M de Murcia Biochem Biophys Res Commun 1995 new
Structures of DNA and RNA polymerases and their interactions with nucleic acid substrates. Edward Arnold, Jianping Ding, Stephen H Hughes, Z Hostomsky Current opinion in structural biology 1995 pols set
An expanded model of replicating human immunodeficiency virus reverse transcriptase. B M Wöhrl, C Tantillo, Edward Arnold, Stuart F J Le Grice Biochemistry 1995 pols set
Insights into DNA polymerization mechanisms from structure and function analysis of HIV-1 reverse transcriptase. P H Patel, A Jacobo-Molina, Jianping Ding, C Tantillo, Art D Clark, R Raag, R G Nanni, Stephen H Hughes, Edward Arnold Biochemistry 1995 pols set
DNA polymerases required for repair of UV-induced damage in Saccharomyces cerevisiae. Martin E Budd, Judith L Campbell Molecular and cellular biology 1995 new
Stimulation of DNA synthesis by mouse DNA helicase B in a DNA replication system containing eukaryotic replication origins. K Matsumoto, Masayuki Seki, Chikahide Masutani, S Tada, Takemi Enomoto, Y Ishimi Biochemistry 1995 new
A screen in Escherichia coli for nucleoside analogs that target human immunodeficiency virus (HIV) reverse transcriptase: coexpression of HIV reverse transcriptase and herpes simplex virus thymidine kinase. Baek Kim, Lawrence A Loeb Journal of virology 1995 pols set
Identification and characterization of a Marek's disease virus gene encoding DNA polymerase. D Sui, P Wu, H J Kung, L F Lee Virus Res 1995 partial results
Purification of bacteriophage phi 29 DNA polymerase. José María Lázaro, Luis Blanco, Margarita Salas Methods in enzymology 1995 pols set
Stimulation of DNA polymerase gamma activity by proliferating cell nuclear antigen. Takahiko Taguchi, Mari Ogihara, T Maekawa, Fumio Hanaoka, Munehiko Tanno Biochem Biophys Res Commun 1995 new
Mammalian DNA nucleotide excision repair reconstituted with purified protein components. A Aboussekhra, M Biggerstaff, M K Shivji, J A Vilpo, V Moncollin, Vladimir N Podust, M Protić, Ulrich Hübscher, J M Egly, Richard D Wood Cell 1995 new
Calf thymus Hsc70 protein protects and reactivates prokaryotic and eukaryotic enzymes. A Ziemienowicz, M Zylicz, C Floth, Ulrich Hübscher The Journal of biological chemistry 1995 new
Template secondary structure can increase the error frequency of the DNA polymerase from Thermus aquaticus. P C Loewen, J Switala Gene 1995 pols set
The anti-proliferative effect of proliferating cell nuclear antigen-specific antisense oligonucleotides on human gastric cancer cell lines. C Sakakura, A Hagiwara, Hajime Tsujimoto, K Ozaki, T Sakakibara, Takuji Oyama, M Ogaki, Tomosaburo Takahashi Surgery today 1995 new
Expression and physicochemical characterization of human proliferating cell nuclear antigen. Peiming Zhang, S J Zhang, Zhenzhong Zhang, J F Woessner, Marietta Y W T Lee Biochemistry 1995 pols set
Structure of the gene for the catalytic subunit of human DNA polymerase delta (POLD1). Long-Sheng Chang, L Zhao, L Zhu, M L Chen, Marietta Y W T Lee Genomics 1995 pols set
Further characterization of the human cell multiprotein DNA replication complex. N Applegren, Robert J Hickey, A M Kleinschmidt, Q Zhou, J Coll, P Wills, R Swaby, Y Wei, J Y Quan, Marietta Y W T Lee Journal of cellular biochemistry 1995 new
Crystal structure of a replication fork single-stranded DNA binding protein (T4 gp32) complexed to DNA. Yousif Shamoo, A M Friedman, M R Parsons, William H Konigsberg, Thomas A Steitz Nature 1995 new
Crystallization of human immunodeficiency virus type 1 reverse transcriptase with and without nucleic acid substrates, inhibitors, and an antibody Fab fragment. Art D Clark, A Jacobo-Molina, Patrick K Clark, Stephen H Hughes, Edward Arnold Methods in enzymology 1995 new
Topographical characterization of the DNA polymerase from Thermus aquaticus. Defining groups of inhibitor mAbs by epitope mapping and functional analysis using surface plasmon resonance. J L Daiss, E R Scalice, D J Sharkey J Immunol Methods 1995 new
Mechanism of inhibition of proliferating cell nuclear antigen-dependent DNA synthesis by the cyclin-dependent kinase inhibitor p21. Vladimir N Podust, L M Podust, F Goubin, B Ducommun, Ulrich Hübscher Biochemistry 1995 new
A mutational analysis of the yeast proliferating cell nuclear antigen indicates distinct roles in DNA replication and DNA repair. R Ayyagari, K J Impellizzeri, B L Yoder, S L Gary, Peter M J Burgers Molecular and cellular biology 1995 new
The intracellular phosphorylation of (-)-2'-deoxy-3'-thiacytidine (3TC) and the incorporation of 3TC 5'-monophosphate into DNA by HIV-1 reverse transcriptase and human DNA polymerase gamma. N M Gray, C L Marr, C R Penn, J M Cameron, R C Bethell Biochem Pharmacol 1995 pols set
Structure-function analysis of the mammalian DNA polymerase beta active site: role of aspartic acid 256, arginine 254, and arginine 258 in nucleotidyl transfer. K L Menge, Z Hostomsky, B R Nodes, G O Hudson, S Rahmati, E W Moomaw, R J Almassy, Z Hostomska Biochemistry 1995 pols set
Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair. Yoshihiro Matsumoto, K Kim Science 1995 new
Rationale for mutagenesis of DNA polymerase active sites: DNA polymerase alpha. William C Copeland, Q Dong, Teresa S-F Wang Methods in enzymology 1995 new
Immunoaffinity purification of DNA polymerase delta. Yanan Jiang, S J Zhang, S M Wu, Marietta Y W T Lee Arch Biochem Biophys 1995 pols set
[Use of thermostable DNA polymerase from Thermus thermophilus KTP in a combined reverse transcription and amplification reaction of detecting interleukin 2alpha RNA and determining expression of the multidrug resistance gene (MDR-1)]. T V Grebennikova, A I Glukhov, L G Chistiakova, V I Kiselev, E S Severin Mol Biol (Mosk) 1995 new
Active site mapping of the catalytic mouse primase subunit by alanine scanning mutagenesis. William C Copeland, X Tan The Journal of biological chemistry 1995 new
Lack of stereospecificity of some cellular and viral enzymes involved in the synthesis of deoxyribonucleotides and DNA: molecular basis for the antiviral activity of unnatural L-beta-nucleosides. Silvio Spadari, Giovanni Maga, A Verri, A Bendiscioli, L Tondelli, M Capobianco, F Colonna, A Garbesi, Federico Focher Biochimie 1995 pols set
Analyzing fidelity of DNA polymerases. Katarzyna Bebenek, Thomas A Kunkel Methods in enzymology 1995 partial results
Gel kinetic analysis of DNA polymerase fidelity in the presence of proofreading using bacteriophage T4 DNA polymerase. S Creighton, Myron F Goodman The Journal of biological chemistry 1995 complete
[Purine arabinonucleoside-5'-triphosphates with substituents in the 2'-position as DNA polymerase substrates]. Iu A Sharkin, E V Kuznetsova, L S Viktorova, L A Aleksandrova Mol Biol (Mosk) 1995 new
Mutational studies of human DNA polymerase alpha. Lysine 950 in the third most conserved region of alpha-like DNA polymerases is involved in binding the deoxynucleoside triphosphate. Q Dong, Teresa S-F Wang The Journal of biological chemistry 1995 pols set
Crystal structure of Thermus aquaticus DNA polymerase. Y Kim, Soo Hyun Eom, Jianhong Wang, D S Lee, S W Suh, Thomas A Steitz Nature 1995 topics set
Selective inhibition of DNA polymerase epsilon by phosphatidylinositol. M Shoji-Kawaguchi, Shunji Izuta, K Tamiya-Koizumi, Motoshi Suzuki, Shonen Yoshida J Biochem 1995 new
A highly efficient procedure for site-specific mutagenesis of full-length plasmids using Vent DNA polymerase. S Byrappa, D K Gavin, K C Gupta Genome Res 1995 new
Interactions of calf thymus DNA polymerase alpha with primer/templates. H C Thompson, R J Sheaff, Robert D Kuchta Nucleic acids research 1995 new
Purification of bacteriophage T4 DNA replication proteins. Nancy G Nossal, D M Hinton, L J Hobbs, P Spacciapoli Methods in enzymology 1995 topics set
Differences in the mechanism of stimulation of T7 DNA polymerase by two binding modes of Escherichia coli single-stranded DNA-binding protein. M N Rigler, Louis J Romano The Journal of biological chemistry 1995 pols set
Stepdown hyperthermia in human melanoma cells: effects on protracted mild hyperthermia for survival and DNA polymerase inactivation. G P Raaphorst, D P Yang, C E Ng Melanoma Res 1995 new
Purification of DNA polymerase III of gram-positive bacteria. Marjorie H Barnes, Neal C Brown Methods in enzymology 1995 new
Mutational analysis of DNA polymerase substrate recognition and subunit interactions using herpes simplex virus as prototype. P Digard, W R Bebrin, Donald M Coen Methods in enzymology 1995 new
[Molecular basis and clinical significance of HIV-1 resistance to nucleoside compounds]. Mark A. Wainberg, Z Gu, H Salomon, E.J. Arts, Lawrence Kleiman, Michael A. Parniak, N Morin Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1995 pols set
Human immunodeficiency virus type 1 reverse transcriptase. 3'-Azidodeoxythymidine 5'-triphosphate inhibition indicates two-step binding for template-primer. M Jaju, William A Beard, Samuel H Wilson The Journal of biological chemistry 1995 pols set
Purification of mammalian DNA polymerases: DNA polymerase alpha. Teresa S-F Wang, William C Copeland, L Rogge, Q Dong Methods in enzymology 1995 pols set
Purification of mammalian polymerases: DNA polymerase delta. Kathleen M Downey, Antero G So Methods in enzymology 1995 new
DNA polymerase beta bypasses in vitro a single d(GpG)-cisplatin adduct placed on codon 13 of the HRAS gene. Jean-Sébastien Hoffmann, Marie-Jeanne Pillaire, Giovanni Maga, V Podust, Ulrich Hübscher, Giuseppe Villani Proceedings of the National Academy of Sciences of the United States of America 1995 new
Proofreading-defective DNA polymerase II increases adaptive mutation in Escherichia coli. Patricia L Foster, G Gudmundsson, J M Trimarchi, H Cai, Myron F Goodman Proceedings of the National Academy of Sciences of the United States of America 1995 partial results
Production of active mouse DNA polymerase delta in bacteria. R Hindges, Ulrich Hübscher Gene 1995 new
Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1. Y Luo, Jerard Hurwitz, J Massagué Nature 1995 new
Action of mitochondrial DNA polymerase gamma at sites of base loss or oxidative damage. Kevin G Pinz, Shinya Shibutani, Daniel F Bogenhagen The Journal of biological chemistry 1995 pols set
Formation of 2-hydroxydeoxyadenosine triphosphate, an oxidatively damaged nucleotide, and its incorporation by DNA polymerases. Steady-state kinetics of the incorporation. Hiroyuki Kamiya, Hironori Kasai The Journal of biological chemistry 1995 partial results
DNA polymerase beta conducts the gap-filling step in uracil-initiated base excision repair in a bovine testis nuclear extract. R K Singhal, Rajendra Prasad, Samuel H Wilson The Journal of biological chemistry 1995 new
Nucleoside drug resistance in HIV-1 reverse transcriptase. P N Yadav, J S Yadav, Mukund J Modak Nature structural biology 1995 pols set
DNA sequencing with delta Taq DNA polymerase. R S Ranu BioTechniques 1995 pols set
Mitochondrial single-stranded DNA-binding protein from Drosophila embryos. Physical and biochemical characterization. P Thömmes, Carol L Farr, R F Marton, Laurie S Kaguni, Sue Cotterill The Journal of biological chemistry 1995 new
Assembly of a chromosomal replication machine: two DNA polymerases, a clamp loader, and sliding clamps in one holoenzyme particle. III. Interface between two polymerases and the clamp loader. R Onrust, Jeff Finkelstein, J Turner, V Naktinis, Mike E O'Donnell The Journal of biological chemistry 1995 new
Glutamine 151 participates in the substrate dNTP binding function of HIV-1 reverse transcriptase. Stefan G Sarafianos, V N Pandey, Neerja Kaushik, Mukund J Modak Biochemistry 1995 pols set
Assembly of a chromosomal replication machine: two DNA polymerases, a clamp loader, and sliding clamps in one holoenzyme particle. I. Organization of the clamp loader. R Onrust, Jeff Finkelstein, V Naktinis, J Turner, L Fang, Mike E O'Donnell The Journal of biological chemistry 1995 pols set
Human immunodeficiency virus type 1 reverse transcriptase tG:T mispair formation on RNA and DNA templates with mismatched primers: a kinetic and thermodynamic study. M Sala, S Wain-Hobson, F Schaeffer The EMBO journal 1995 pols set
Expression of the catalytic subunit of human DNA polymerase delta in mammalian cells using a vaccinia virus vector system. Peiming Zhang, I Frugulhetti, Yanan Jiang, G L Holt, R C Condit, Marietta Y W T Lee The Journal of biological chemistry 1995 pols set
DNA polymerase epsilon interacts with proliferating cell nuclear antigen in primer recognition and elongation. Giovanni Maga, Ulrich Hübscher Biochemistry 1995 new
Purification and enzymatic and functional characterization of DNA polymerase beta-like enzyme, POL4. expressed during yeast meiosis. Martin E Budd, Judith L Campbell Methods in enzymology 1995 new
DNA damage-induced transcriptional activation of a human DNA polymerase beta chimeric promoter: recruitment of preinitiation complex in vitro by ATF/CREB. Satya Narayan, William A Beard, Samuel H Wilson Biochemistry 1995 pols set
The effects of the ring fragmentation product of thymidine C5-hydrate on phosphodiesterases and klenow (exo-) fragment. T J Matray, K J Haxton, Marc M Greenberg Nucleic acids research 1995 pols set
High resolution structures of HIV-1 RT from four RT-inhibitor complexes. Jingshan Ren, R Esnouf, E Garman, D Somers, C Ross, I Kirby, J Keeling, G Darby, Y Jones, David I Stuart Nat Struct Biol 1995 topics set
Single-step purification of a thermostable DNA polymerase expressed in Escherichia coli. U J Desai, P K Pfaffle BioTechniques 1995 pols set
Purification of Escherichia coli DNA polymerase I and Klenow fragment. Catherine M Joyce, V Derbyshire Methods in enzymology 1995 topics set
Induction of DNA polymerase beta and gamma in the lungs of age-related oxygen tolerant rats. S Jinno, K Kida, Takahiko Taguchi Mech Ageing Dev 1995 new
Protein-nucleic acid interactions in bacteriophage phi 29 DNA replication. Margarita Salas, R Freire, M S Soengas, J A Esteban, Juan Méndez, Alicia Bravo, M Serrano, M A Blasco, José María Lázaro, Luis Blanco FEMS microbiology reviews 1995 new
Reduced frameshift fidelity and processivity of HIV-1 reverse transcriptase mutants containing alanine substitutions in helix H of the thumb subdomain. Katarzyna Bebenek, William A Beard, J R Casas-Finet, H R Kim, Thomas A Darden, Samuel H Wilson, Thomas A Kunkel The Journal of biological chemistry 1995 pols set
A single residue in DNA polymerases of the Escherichia coli DNA polymerase I family is critical for distinguishing between deoxy- and dideoxyribonucleotides. Stanley Tabor, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 1995 topics set
Human immunodeficiency virus reverse transcriptase substitutes for DNA polymerase I in Escherichia coli. Baek Kim, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1995 new
Helix-destabilizing activity of phi 29 single-stranded DNA binding protein: effect on the elongation rate during strand displacement DNA replication. M S Soengas, C Gutiérrez, Margarita Salas Journal of molecular biology 1995 new
Inactivation of the 5'-3' exonuclease of Thermus aquaticus DNA polymerase. L S Merkens, S K Bryan, Robb E Moses Biochimica et biophysica acta 1995 pols set
Characterization of DNA polymerase beta mutants with amino acid substitutions located in the C-terminal portion of the enzyme. Joann B Sweasy, M S Yoon Mol Gen Genet 1995 new
DNA polymerase epsilon links the DNA replication machinery to the S phase checkpoint. T A Navas, Z Zhou, S J Elledge Cell 1995 pols set
Interferon-alpha directly inhibits DNA polymerase activity in isolated chromatin nucleoprotein complexes: correlation with IFN-alpha treatment outcome in patients with chronic myelogenous leukemia. N L Nicolson, M Talpaz, G L Nicolson Gene 1995 new
N7-cyanoborane-2'-deoxyguanosine 5'-triphosphate is a good substrate for DNA polymerase. K W Porter, J Tomasz, F Huang, A Sood, B R Shaw Biochemistry 1995 new
Deoxynucleoside triphosphate and pyrophosphate binding sites in the catalytically competent ternary complex for the polymerase reaction catalyzed by DNA polymerase I (Klenow fragment). Mekbib Astatke, Nigel D F Grindley, Catherine M Joyce The Journal of biological chemistry 1995 pols set
Purification of Escherichia coli DNA polymerase III holoenzyme. M G Cull, Charles S McHenry Methods in enzymology 1995 pols set
Stimulation of Drosophila mitochondrial DNA polymerase by single-stranded DNA-binding protein. A J Williams, Laurie S Kaguni The Journal of biological chemistry 1995 new
Selective inhibition of DNA polymerase-alpha family with chemically synthesized derivatives of PHYLPA, a unique Physarum lysophosphatidic acid. K Murakami-Murofushi, Susumu Kobayashi, K Onimura, M Matsumoto, M Shioda, Shonen Yoshida, M Shoji, H Murofushi Biochimica et biophysica acta 1995 new
Isolation and characterization of ten mutator alleles of the mitochondrial DNA polymerase-encoding MIP1 gene from Saccharomyces cerevisiae. J P Hu, S Vanderstraeten, Françoise Foury Gene 1995 pols set
The antimutagenic effect of a truncated epsilon subunit of DNA polymerase III in Escherichia coli cells irradiated with UV light. M Kanabus, A Nowicka, E Sledziewska-Gójska, Piotr Jonczyk, Z Ciesla Mol Gen Genet 1995 new
Polymerase delta variants in RER colorectal tumours. L T da Costa, B Liu, W el-Deiry, S R Hamilton, K W Kinzler, B Vogelstein, S Markowitz, J K Willson, A de la Chapelle, Kathleen M Downey Nat Genet 1995 new
Aphidicolin-sensitive DNA polymerase is incorporated into the chromatin during nuclear envelope assembly in Xenopus egg extract. Y Takasuga, M Murata, J Yamashita, T Andoh, T Yagura Exp Cell Res 1995 new
Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors. R Esnouf, Jingshan Ren, C Ross, Y Jones, D Stammers, David I Stuart Nat Struct Biol 1995 topics set
DNA polymerase action on an oligonucleotide containing a site-specifically located N-(deoxyguanosin-8-yl)-1-aminopyrene. R R Vyas, A K Basu Carcinogenesis 1995 pols set
Properties of mitochondrial DNA polymerase in mitochondrial DNA synthesis in yeast. T K Biswas, P Sengupta, R Green, P Hakim, B Biswas, S Sen Acta Biochim Pol 1995 new
Antiviral therapy for human immunodeficiency virus infections. Erik De Clercq Clinical microbiology reviews 1995 new
Preclinical evaluation of HBY 097, a new nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 replication. Jörg-Peter Kleim, R Bender, R Kirsch, C Meichsner, A Paessens, M Rösner, H Rübsamen-Waigmann, R Kaiser, M Wichers, K E Schneweis Antimicrobial agents and chemotherapy 1995 pols set
Kinetic analysis of nucleotide incorporation and misincorporation by Klenow fragment of Escherichia coli DNA polymerase I. Stephen J Benkovic, Craig E Cameron Methods in enzymology 1995 topics set
Structure-activity and cross-resistance evaluations of a series of human immunodeficiency virus type-1-specific compounds related to oxathiin carboxanilide. Robert W Buckheit, T L Kinjerski, V Fliakas-Boltz, J D Russell, T L Stup, L A Pallansch, W G Brouwer, D C Dao, W A Harrison, R J Schultz Antimicrobial agents and chemotherapy 1995 pols set
Suppression of the breakthrough of human immunodeficiency virus type 1 (HIV-1) in cell culture by thiocarboxanilide derivatives when used individually or in combination with other HIV-1-specific inhibitors (i.e., TSAO derivatives). Jan Balzarini, María-Jesús Pérez-Pérez, S Vélazquez, Ana San-Félix, María-José Camarasa, Erik De Clercq, Anna Karlsson Proceedings of the National Academy of Sciences of the United States of America 1995 pols set
L-743, 726 (DMP-266): a novel, highly potent nonnucleoside inhibitor of the human immunodeficiency virus type 1 reverse transcriptase. S D Young, S F Britcher, L O Tran, L S Payne, W C Lumma, T A Lyle, J R Huff, P S Anderson, David B Olsen, Steven S Carroll Antimicrobial agents and chemotherapy 1995 pols set
A novel kinetic analysis to calculate nucleotide affinity of proofreading DNA polymerases. Application to phi 29 DNA polymerase fidelity mutants. J Saturno, Luis Blanco, Margarita Salas, J A Esteban The Journal of biological chemistry 1995 topics set
Developmental activity variations of DNA polymerase alpha, delta, epsilon in mouse forebrains and spleens. R Yang, Chengping Lu Sci China B 1995 new
Ginsenosides activate DNA polymerase delta from bovine placenta. S W Cho, E H Cho, S Y Choi Life Sci 1995 new
Specific inhibition of herpes simplex virus DNA polymerase by helical peptides corresponding to the subunit interface. P Digard, K P Williams, P Hensley, I S Brooks, C E Dahl, Donald M Coen Proceedings of the National Academy of Sciences of the United States of America 1995 new
Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5-A resolution: structural basis for thermostability. S Korolev, M Nayal, Wayne M Barnes, E Di Cera, Gabriel Waksman Proceedings of the National Academy of Sciences of the United States of America 1995 topics set
The 3'-5' exonuclease site of DNA polymerase III from gram-positive bacteria: definition of a novel motif structure. Marjorie H Barnes, P Spacciapoli, D H Li, Neal C Brown Gene 1995 new
An improved phage display antibody cloning system using newly designed PCR primers optimized for Pfu DNA polymerase. H I Yamanaka, Y Kirii, H Ohmoto J Biochem 1995 pols set
Enthalpy-entropy compensation in DNA melting thermodynamics. John Petruska, Myron F Goodman The Journal of biological chemistry 1995 new
Novel mutations in reverse transcriptase of human immunodeficiency virus type 1 reduce susceptibility to foscarnet in laboratory and clinical isolates. John W Mellors, Holly Z Bazmi, Raymond F Schinazi, B M Roy, Y Hsiou, Edward Arnold, J Weir, D L Mayers Antimicrob Agents Chemother 1995 topics set
Characterization of crystals of the thermostable DNA polymerase I from Thermus aquaticus. U K Urs, D J Sharkey, T S Peat, W A Hendrickson, K Murthy Proteins 1995 pols set
HIV pathogenesis. Lines drawn in epitope wars. John M Coffin Nature 1995 new
Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides. T Shirasaka, M F Kavlick, Takayuki Ueno, W Y Gao, E Kojima, M L Alcaide, S Chokekijchai, B M Roy, Edward Arnold, R Yarchoan Proceedings of the National Academy of Sciences of the United States of America 1995 new
Highly selective affinity labeling of DNA polymerase alpha-primase from human placenta by reactive analogs of ATP. O D Zakharova, Vladimir N Podust, A A Mustaev, Rashid O Anarbaev, Olga I Lavrik Biochimie 1995 new
Stereospecificity of human DNA polymerases alpha, beta, gamma, delta and epsilon, HIV-reverse transcriptase, HSV-1 DNA polymerase, calf thymus terminal transferase and Escherichia coli DNA polymerase I in recognizing D- and L-thymidine 5'-triphosphate as substrate. Federico Focher, Giovanni Maga, A Bendiscioli, M Capobianco, F Colonna, A Garbesi, Silvio Spadari Nucleic acids research 1995 pols set
Synergistic effects on ganglionic herpes simplex virus infections by mutations or drugs that inhibit the viral polymerase and thymidine kinase. J Jacobson, M Kramer, F Rozenberg, A Hu, Donald M Coen Virology 1995 new
Assembly of a chromosomal replication machine: two DNA polymerases, a clamp loader, and sliding clamps in one holoenzyme particle. II. Intermediate complex between the clamp loader and its clamp. V Naktinis, R Onrust, L Fang, Mike E O'Donnell The Journal of biological chemistry 1995 new
Mutations that specifically impair the DNA binding activity of the herpes simplex virus protein UL42. C S Chow, Donald M Coen Journal of virology 1995 new
Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution. Jianping Ding, Kalyan Das, C Tantillo, Weiming Zhang, Arthur D Clark, S Jessen, Xiaoqing Lu, Y Hsiou, A Jacobo-Molina, Koen Andries Structure (London, England : 1993) 1995 topics set
Reverse transcriptase mutations in sequential HIV-1 isolates in a patient with AIDS. A D Gurusinghe, S A Land, C Birch, C McGavin, D J Hooker, G Tachedjian, R Doherty, N J Deacon Journal of medical virology 1995 pols set
Interaction of herpes simplex virus 1 origin-binding protein with DNA polymerase alpha. S S Lee, Q Dong, Teresa S-F Wang, I. Robert Lehman Proceedings of the National Academy of Sciences of the United States of America 1995 new
An altered spectrum of herpes simplex virus mutations mediated by an antimutator DNA polymerase. Charles B C Hwang, H J Chen Gene 1995 new
Tyrosine 114 is essential for the trimeric structure and the functional activities of human proliferating cell nuclear antigen. Z O Jónsson, Vladimir N Podust, L M Podust, Ulrich Hübscher The EMBO journal 1995 new
Cloning, sequencing, and functional characterization of the two subunits of the pseudorabies virus DNA polymerase holoenzyme: evidence for specificity of interaction. H Berthomme, S J Monahan, Deborah S Parris, B Jacquemont, A L Epstein J Virol 1995 new
Photochemical cross-linking of DNA replication proteins at primer terminus. T L Capson, Stephen J Benkovic, Nancy G Nossal Methods in enzymology 1995 topics set
The hyperthermophilic archaeon Pyrodictium occultum has two alpha-like DNA polymerases. Takashi Uemori, Yoshizumi Ishino, H Doi, Ikunoshin Kato Journal of bacteriology 1995 partial results
Assembly of a chromosomal replication machine: two DNA polymerases, a clamp loader, and sliding clamps in one holoenzyme particle. V. Four different polymerase-clamp complexes on DNA. P T Stukenberg, Mike E O'Donnell The Journal of biological chemistry 1995 pols set
Metabolic pathways for activation of the antiviral agent 9-(2-phosphonylmethoxyethyl)adenine in human lymphoid cells. B L Robbins, J Greenhaw, M C Connelly, A Fridland Antimicrob Agents Chemother 1995 new
Lagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen. Xincang Li, Jinming Li, J Harrington, M R Lieber, Peter M J Burgers The Journal of biological chemistry 1995 pols set
Feline immunodeficiency virus reverse transcriptase: expression, functional characterization, and reconstitution of the 66- and 51-kilodalton subunits. Mario Amacker, M Hottiger, Ulrich Hübscher Journal of virology 1995 new
Recognition by viral and cellular DNA polymerases of nucleosides bearing bases with nonstandard hydrogen bonding patterns. J Horlacher, M Hottiger, Vladimir N Podust, Ulrich Hübscher, Steven A Benner Proceedings of the National Academy of Sciences of the United States of America 1995 pols set
Effects of gypenosides on mouse splenic lymphocyte transformation and DNA polymerase II activity in vitro. D F Liao, N Lu, L S Lei, L Yu, J X Chen Zhongguo Yao Li Xue Bao 1995 new
Mutated K65R recombinant reverse transcriptase of human immunodeficiency virus type 1 shows diminished chain termination in the presence of 2',3'-dideoxycytidine 5'-triphosphate and other drugs. Z Gu, E.J. Arts, Michael A. Parniak, Mark A. Wainberg Proceedings of the National Academy of Sciences of the United States of America 1995 pols set
Misincorporation of dAMP opposite 2-hydroxyadenine, an oxidative form of adenine. Hiroyuki Kamiya, Tadamasa Ueda, T Ohgi, Akio Matsukage, Hironori Kasai Nucleic acids research 1995 topics set
Structure-function analysis of 3'-->5'-exonuclease of DNA polymerases. V Derbyshire, J K Pinsonneault, Catherine M Joyce Methods in enzymology 1995 topics set
DNA polymerase delta holoenzyme: action on single-stranded DNA and on double-stranded DNA in the presence of replicative DNA helicases. Vladimir N Podust, L M Podust, F Müller, Ulrich Hübscher Biochemistry 1995 new
[Use of thermostable DNA polymerase from Thermus thermophilus KTP in a combined reverse transcription and amplification reaction for detecting CD4 receptor mRNA]. A I Glukhov, T V Grebennikova, V I Kiselev, E S Severin Mol Biol (Mosk) 1995 new
Inter-species DNA polymerase delta chimeras are functional in Saccharomyces cerevisiae. G Moussy, A M de Recondo, Giuseppe Baldacci Eur J Biochem 1995 new
Suppressors of thermosensitive mutations in the DNA polymerase delta gene of Saccharomyces cerevisiae. L Giot, M Simon, C Dubois, G Faye Mol Gen Genet 1995 pols set
Mechanism of inhibition of HIV-1 reverse transcriptase by nonnucleoside inhibitors. R A Spence, W M Kati, Karen S Anderson, Kenneth A Johnson Science 1995 new
Differential activities of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives against different human immunodeficiency virus type 1 mutant strains. Jan Balzarini, Masanori Baba, Erik De Clercq Antimicrobial agents and chemotherapy 1995 pols set
Novel concepts in the treatment of human immunodeficiency virus type 1 (HIV-1) infections by HIV-1-specific reverse transcriptase inhibitors. Jan Balzarini Verhandelingen - Koninklijke Academie voor Geneeskunde van België 1995 pols set
Cytotoxicity of 3'-azido-3'-deoxythymidine correlates with 3'-azidothymidine-5'-monophosphate (AZTMP) levels, whereas anti-human immunodeficiency virus (HIV) activity correlates with 3'-azidothymidine-5'-triphosphate (AZTTP) levels in cultured CEM T-lymphoblastoid cells. Y Törnevik, B Ullman, Jan Balzarini, B Wahren, Staffan Eriksson Biochemical pharmacology 1995 pols set
Synthesis and anti-HIV activity of [AZT]-[TSAO-T] and [AZT]-[HEPT] dimers as potential multifunctional inhibitors of HIV-1 reverse transcriptase. Sonsoles Velázquez, R Alvarez, Ana San-Félix, M L Jimeno, Erik De Clercq, Jan Balzarini, María-José Camarasa Journal of medicinal chemistry 1995 pols set
Sensitivity/resistance profile of a simian immunodeficiency virus containing the reverse transcriptase gene of human immunodeficiency virus type 1 (HIV-1) toward the HIV-1-specific non-nucleoside reverse transcriptase inhibitors. Jan Balzarini, M Weeger, María-José Camarasa, Erik De Clercq, K Uberla Biochemical and biophysical research communications 1995 pols set
Learning about DNA polymerase function by studying antimutator DNA polymerases. Linda J Reha-Krantz Trends in biochemical sciences 1995 complete
Efficient replication of polyomavirus DNA in a cell-free system supplemented with Escherichia coli single-stranded DNA binding protein, which exhibits species-specificity in the requirement for DNA polymerase alpha-primase. Toshihiko Eki, Fumio Hanaoka, T Kohda, Masayuki Seki, M Ui, Takemi Enomoto Journal of biochemistry 1995 new
Characterization of a new DNA polymerase from Schizosaccharomyces pombe: a probable homologue of the Saccharomyces cerevisiae DNA polymerase gamma. P A Ropp, William C Copeland Gene 1995 partial results
The large subunit of HIV-1 reverse transcriptase interacts with beta-actin. M Hottiger, K Gramatikoff, O Georgiev, C Chaponnier, W Schaffner, Ulrich Hübscher Nucleic acids research 1995 pols set
Strategic down-regulation of DNA polymerase beta by antisense RNA sensitizes mammalian cells to specific DNA damaging agents. Julie K Horton, Deepak K Srivastava, B Z Zmudzka, Samuel H Wilson Nucleic acids research 1995 pols set
Approach to genotyping errors caused by nontemplated nucleotide addition by Taq DNA polymerase. J R Smith, J D Carpten, M J Brownstein, Sharmistha Ghosh, V L Magnuson, D A Gilbert, J M Trent, F S Collins Genome Res 1995 pols set
Construction of a fusion protein between B subunit of E. coli heat-labile enterotoxin and the C-terminus of herpes simplex virus-DNA polymerase. Arianna Loregian, A Marcello, T R Hirst, Howard S Marsden, Giorgio Palù Biochem Soc Trans 1995 new
8-Hydroxyadenine (7,8-dihydro-8-oxoadenine) induces misincorporation in in vitro DNA synthesis and mutations in NIH 3T3 cells. Hiroyuki Kamiya, H Miura, N Murata-Kamiya, H Ishikawa, T Sakaguchi, H Inoue, T Sasaki, Chikahide Masutani, Fumio Hanaoka, Susumu Nishimura Nucleic acids research 1995 pols set
Inactivation of DNA polymerase alpha-primase by acrolein: loss of activity depends on the DNA substrate. C E Catalano, Robert D Kuchta Biochem Biophys Res Commun 1995 new
Inhibition of human immunodeficiency virus type 1 wild-type and mutant reverse transcriptases by the phenyl ethyl thiazolyl thiourea derivatives trovirdine and MSC-127. Haijiang Zhang, L Vrang, K Bäckbro, P Lind, Christer Sahlberg, Torsten Unge, Bo Oberg Antiviral research 1995 pols set
DNA polymerase I function is required for the utilization of ethanolamine, 1,2-propanediol, and propionate by Salmonella typhimurium LT2. M R Rondon, A R Horswill, J C Escalante-Semerena J Bacteriol 1995 new
Resistance to 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives is generated by mutations at multiple sites in the HIV-1 reverse transcriptase. Robert W Buckheit, V Fliakas-Boltz, S Yeagy-Bargo, O Weislow, D L Mayers, Paul L Boyer, Stephen H Hughes, B C Pan, S H Chu, J P Bader Virology 1995 pols set
DNA nick processing by exonuclease and polymerase activities of bacteriophage T4 DNA polymerase accounts for acridine-induced mutation specificities in T4. V L Kaiser, L S Ripley Proceedings of the National Academy of Sciences of the United States of America 1995 complete
HIV-1 reverse transcriptase-associated RNase H cleaves RNA/RNA in arrested complexes: implications for the mechanism by which RNase H discriminates between RNA/RNA and RNA/DNA. Matthias Götte, S Fackler, T Hermann, E Perola, Luciano Cellai, H J Gross, Stuart F J Le Grice, H Heumann The EMBO journal 1995 pols set
Nascent human immunodeficiency virus type 1 reverse transcription occurs within an enveloped particle. Hongxing Zhang, Yang Zhang, T Spicer, D Henrard, B J Poiesz Journal of virology 1995 pols set
Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase. L M Mansky, H M Temin J Virol 1995 pols set
DnaX complex of Escherichia coli DNA polymerase III holoenzyme. Physical characterization of the DnaX subunits and complexes. H Garry Dallmann, Charles S McHenry The Journal of biological chemistry 1995 pols set
In vitro replication by prokaryotic and eukaryotic polymerases on DNA templates containing site-specific and stereospecific benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide adducts. Parvathi Chary, R Stephen Lloyd Nucleic acids research 1995 pols set
Purification and properties of DNA polymerase II from Escherichia coli. H Cai, Hong Yu, K McEntee, Myron F Goodman Methods in enzymology 1995 pols set
Solution structure of DNA polymerases and DNA polymerase-substrate complexes. Gregory P Mullen Methods in enzymology 1995 new
Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors. Jianping Ding, Kalyan Das, H Moereels, Luc Koymans, Koen Andries, Paul A J Janssen, Stephen H Hughes, Edward Arnold Nat Struct Biol 1995 topics set
Accessory proteins function as matchmakers in the assembly of the T4 DNA polymerase holoenzyme. B F Kaboord, Stephen J Benkovic Current biology : CB 1995 topics set
Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint. Hiroyuki Araki, S H Leem, A Phongdara, Akio Sugino Proceedings of the National Academy of Sciences of the United States of America 1995 pols set
Effect of site-specifically located aristolochic acid DNA adducts on in vitro DNA synthesis by human DNA polymerase alpha. T H Broschard, M Wiessler, H H Schmeiser Cancer Lett 1995 pols set
An aphidicolin-resistant mutant of Chinese hamster ovary cell with altered DNA polymerase and 3' exonuclease activities. Z Fehér, N C Mishra Biochimica et biophysica acta 1995 new
Phorbol ester abrogates up-regulation of DNA polymerase beta by DNA-alkylating agents in Chinese hamster ovary cells. Deepak K Srivastava, Teresa Y Rawson, S D Showalter, Samuel H Wilson The Journal of biological chemistry 1995 pols set
Identification, localization, transcription, and sequence analysis of the Choristoneura fumiferana nuclear polyhedrosis virus DNA polymerase gene. J J Liu, E B Carstens Virology 1995 new
The bovine DNA polymerase beta promoter: cloning, characterization and comparison with the human core promoter. K H Chen, T Wood, Feng He, Satya Narayan, Samuel H Wilson Gene 1995 pols set
[Hepatitis B virus specific DNA polymerase activity as a sensitive marker of viral replication]. Kazuharu Matsuura, Kazuo Tobe, T Tsuji Nippon Rinsho 1995 new
Increased reliability of selective PCR by using additionally mutated primers and a commercial Taq DNA polymerase enhancer. A De Milito, M Catucci, F Iannelli, L Romano, M Zazzi, P E Valensin Mol Biotechnol 1995 pols set
Purification and domain-mapping of mammalian DNA polymerase beta. William A Beard, Samuel H Wilson Methods in enzymology 1995 pols set
On the mechanism of preferential incorporation of dAMP at abasic sites in translesional DNA synthesis. Role of proofreading activity of DNA polymerase and thermodynamic characterization of model template-primers containing an abasic site. Hiroshi Ide, H Murayama, S Sakamoto, K Makino, K Honda, H Nakamuta, Mitsuru Sasaki, N Sugimoto Nucleic acids research 1995 new
Expression of the Epstein-Barr virus DNA polymerase in Escherichia coli for use as antigen for the diagnosis of nasopharyngeal carcinoma. L S Lin, L H Ro, M S Lo, W L Huang, J Ma, T H Chang, C H Shu, K C Chow, W T Liu, K Y Chen J Med Virol 1995 new
Nucleotide sequence and transcription of the left early region of Streptococcus pneumoniae bacteriophage Cp-1 coding for the terminal protein and the DNA polymerase. A C Martín, R López, P García Virology 1995 new
Comparison of incorporation and extension of nucleotides in vitro opposite 8-hydroxyguanine (7,8-dihydro-8-oxoguanine) in hot spots of the c-Ha-ras gene. Hiroyuki Kamiya, N Murata-Kamiya, M Fujimuro, K Kido, H Inoue, Susumu Nishimura, Chikahide Masutani, Fumio Hanaoka, E Ohtsuka Japanese journal of cancer research : Gann 1995 pols set
DNA replication. A familiar ring to DNA polymerase processivity. C Wyman, M Botchan Current biology : CB 1995 new
Rapid changes in human immunodeficiency virus type 1 RNA load and appearance of drug-resistant virus populations in persons treated with lamivudine (3TC). Rob Schuurman, Monique Nijhuis, R van Leeuwen, P Schipper, D de Jong, P Collis, Sven A Danner, J Mulder, C Loveday, C Christopherson J Infect Dis 1995 new
Direct solid-phase sequence analysis of the human p53 gene by use of multiplex polymerase chain reaction and alpha-thiotriphosphate nucleotides. C Berg, A Hedrum, A Holmberg, F Pontén, M Uhlén, J Lundeberg Clin Chem 1995 new
Modular organization of T4 DNA polymerase. Evidence from phylogenetics. C C Wang, L S Yeh, Jim D Karam The Journal of biological chemistry 1995 complete
A ring to bind eukaryotic DNA polymerase. Peter H von Hippel Structure (London, England : 1993) 1995 new
Effect of aminofluorene and (acetylamino)fluorene adducts on the DNA replication mediated by Escherichia coli polymerases I (Klenow fragment) and III. R Doisy, M S Tang Biochemistry 1995 pols set
A non-radioactive DNA sequencing method using biotinylated dideoxynucleoside triphosphates and delta Tth DNA polymerase. Kyoji Ikeda, Hirokazu Inoue, M Oka, B Kawakami, Y Kawamura DNA Res 1995 topics set
Site-directed mutagenesis of arginine 72 of HIV-1 reverse transcriptase. Catalytic role and inhibitor sensitivity. Stefan G Sarafianos, V N Pandey, Neerja Kaushik, Mukund J Modak The Journal of biological chemistry 1995 topics set
DNA strand transfer catalyzed by the 5'-3' exonuclease domain of Escherichia coli DNA polymerase I. Weiming Zhang, David H Evans Nucleic acids research 1995 complete David H Evans*
Fidelity of DNA polymerases for PCR. P N Hengen Trends in biochemical sciences 1995 pols set
Further characterization of HeLa DNA polymerase epsilon. G Chui, Stuart Linn The Journal of biological chemistry 1995 partial results
The amino acid sequence required for 5' --> 3' exonuclease activity of Bacillus caldotenax DNA polymerase. Yoshizumi Ishino, A Takahashi-Fujii, Takashi Uemori, M Imamura, Ikunoshin Kato, H Doi Protein Eng 1995 new
Enzymatic characterization of human immunodeficiency virus type 1 reverse transcriptase resistant to multiple 2',3'-dideoxynucleoside 5'-triphosphates. Takayuki Ueno, T Shirasaka, Hiroyuki Mitsuya The Journal of biological chemistry 1995 topics set
DNA polymerase beta can substitute for DNA polymerase I in the initiation of plasmid DNA replication. Joann B Sweasy, M Chen, Lawrence A Loeb J Bacteriol 1995 pols set
Cloning and complete sequence of the DNA polymerase-encoding gene (BstpolI) and characterisation of the Klenow-like fragment from Bacillus stearothermophilus. S M Phang, C Y Teo, E Lo, V W Wong Gene 1995 pols set
Structural and functional similarities of prokaryotic and eukaryotic DNA polymerase sliding clamps. Zvi Kelman, Mike E O'Donnell Nucleic acids research 1995 new
The nucleotide analog 2-aminopurine as a spectroscopic probe of nucleotide incorporation by the Klenow fragment of Escherichia coli polymerase I and bacteriophage T4 DNA polymerase. M W Frey, L C Sowers, David P Millar, Stephen J Benkovic Biochemistry 1995 topics set
Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy. Brendan A Larder, S D Kemp, P Richard Harrigan Science 1995 pols set
Mutagenesis in Escherichia coli by three O6-substituted guanines in double-stranded or gapped plasmids. Gary T Pauly, Stephen H Hughes, R C Moschel Biochemistry 1995 new
Analysis of mutations at position 184 in reverse transcriptase of human immunodeficiency virus type 1. Paul L Boyer, Stephen H Hughes Antimicrobial agents and chemotherapy 1995 new
Truncating alpha-helix E' of p66 human immunodeficiency virus reverse transcriptase modulates RNase H function and impairs DNA strand transfer. M Ghosh, K J Howard, Craig E Cameron, Stephen J Benkovic, Stephen H Hughes, Stuart F J Le Grice The Journal of biological chemistry 1995 pols set
Using macromolecular crowding agents to identify weak interactions within DNA replication complexes. M K Reddy, S E Weitzel, S S Daube, Thale C Jarvis, Peter H von Hippel Methods in enzymology 1995 complete
Development of HIV-1 resistance to (-)2'-deoxy-3'-thiacytidine in patients with AIDS or advanced AIDS-related complex. Mark A. Wainberg, H Salomon, Z Gu, Julio S G Montaner, T P Cooley, R McCaffrey, J Ruedy, H M Hirst, Nick Cammack, J Cameron AIDS (London, England) 1995 new
Targeting HIV reverse transcriptase in novel ways. Mark A. Wainberg, Z Gu Nature medicine 1995 pols set
DnaX complex of Escherichia coli DNA polymerase III holoenzyme. Central role of tau in initiation complex assembly and in determining the functional asymmetry of holoenzyme. H Garry Dallmann, R L Thimmig, Charles S McHenry The Journal of biological chemistry 1995 pols set
Subunit structure of mitochondrial DNA polymerase from Drosophila embryos. Physical and immunological studies. M W Olson, Yazhen Wang, R H Elder, Laurie S Kaguni The Journal of biological chemistry 1995 new
Expression patterns of DNA replication enzymes and the regulatory factor DREF during Drosophila development analyzed with specific antibodies. Masamitsu Yamaguchi, Fumiko Hirose, Y Nishimoto, T Naruge, M Ikeda, T Hachiya, Katsuyuki Tamai, Kazufumi Kuroda, Akio Matsukage Biology of the cell / under the auspices of the European Cell Biology Organization 1995 new
The DRE sequence TATCGATA, a putative promoter-activating element for Drosophila melanogaster cell-proliferation-related genes. Akio Matsukage, Fumiko Hirose, Y Hayashi, K Hamada, Masamitsu Yamaguchi Gene 1995 new
Characterisation of foscarnet-resistant strains of human immunodeficiency virus type 1. G Tachedjian, D J Hooker, A D Gurusinghe, H Bazmi, N J Deacon, J Mellors, C Birch, J Mills Virology 1995 topics set
Cell killing, DNA polymerase inactivation and radiosensitization to low dose rate irradiation by mild hyperthermia in four human cell lines. G P Raaphorst, D P Yang, A Bussey, C E Ng Int J Hyperthermia 1995 new
Construction and expression of a chimeric gene encoding human terminal deoxynucleotidyltransferase and DNA polymerase beta. J D Quintana-Hau, S Uribe-Luna, M Espinosa-Lara, R Maldonado-Rodríguez, N Logsdon, K L Beattie Gene 1995 new
Maize DNA polymerase 2 is a phosphoprotein with increasing activity during germination. P Coello, J M Vázquez-Ramos Eur J Biochem 1995 new
[New nucleotide inhibitors of human DNA polymerase alpha]. D G Semizarov, M V Ias'ko, M K Kukhanova, A A Kraevskiĭ Mol Biol (Mosk) 1995 pols set
Crystallization and preliminary X-ray crystallographic analysis of DNA polymerase from Thermus aquaticus. Soo Hyun Eom, H K Song, S W Suh, Y Kim, Thomas A Steitz, J H Park, Joong Su Kim, Suk-Tae Kwon, D S Lee Acta crystallographica. Section D, Biological crystallography 1995 new
Properties of the 5'-->3' exonuclease/ribonuclease H activity of Thermus thermophilus DNA polymerase. T Auer, P A Landre, T W Myers Biochemistry 1995 new
A conserved region in the amino terminus of DNA polymerase delta is involved in proliferating cell nuclear antigen binding. S J Zhang, X R Zeng, Peiming Zhang, N L Toomey, R Y Chuang, Long-Sheng Chang, Marietta Y W T Lee The Journal of biological chemistry 1995 pols set
Dynamics of bacteriophage T4 DNA polymerase function: identification of amino acid residues that affect switching between polymerase and 3' --> 5' exonuclease activities. S A Stocki, R L Nonay, Linda J Reha-Krantz Journal of molecular biology 1995 complete
Purification of mammalian polymerases: DNA polymerase epsilon. G S Chui, Stuart Linn Methods in enzymology 1995 new
Large complexes of beta-poly(L-malate) with DNA polymerase alpha, histones, and other proteins in nuclei of growing plasmodia of Physarum polycephalum. Bernhard Angerer, Eggehard Holler Biochemistry 1995 new
DNA and RNA-DNA annealing activity associated with the tau subunit of the Escherichia coli DNA polymerase III holoenzyme. Sangbumn Kim, K J Marians Nucleic acids research 1995 pols set
Escherichia coli DNA polymerase III holoenzyme subunits alpha, beta, and gamma directly contact the primer-template. J A Reems, S Wood, Charles S McHenry The Journal of biological chemistry 1995 pols set
DNA polymerase delta of Physarum polycephalum. G Achhammer, A Winkler, Bernhard Angerer, Eggehard Holler Curr Genet 1995 new
Use of genetic analyses to probe structure, function, and dynamics of bacteriophage T4 DNA polymerase. Linda J Reha-Krantz Methods in enzymology 1995 complete
K65R mutation of human immunodeficiency virus type 1 reverse transcriptase encodes cross-resistance to 9-(2-phosphonylmethoxyethyl)adenine. Z Gu, H Salomon, J M Cherrington, A S Mulato, M S Chen, R Yarchoan, A Foli, K M Sogocio, Mark A. Wainberg Antimicrobial agents and chemotherapy 1995 new
Insulin-like growth factor 1 and insulin inhibit HIV type 1 replication in cultured cells. R J Germinario, T DeSantis, Mark A. Wainberg AIDS research and human retroviruses 1995 pols set
Inhibition of human immunodeficiency virus type 1 multiplication by transforming growth factor beta 1 and AZT in HIV-1-infected myeloid cells. V McKiel, Z Gu, Mark A. Wainberg, J Hiscott Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1995 pols set
Analysis of Primer Extension and the First Template Switch during Human Immunodeficiency Virus Reverse Transcription. E.J. Arts, Zhongjie Li, Mark A. Wainberg Journal of biomedical science 1995 pols set
Cellular factors required for papillomavirus DNA replication. T Melendy, Juhan Sedman, A Stenlund Journal of virology 1995 topics set
The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1. D W Rodgers, S J Gamblin, B A Harris, S Ray, J S Culp, B Hellmig, D J Woolf, C Debouck, S C Harrison Proceedings of the National Academy of Sciences of the United States of America 1995 topics set
Human immunodeficiency virus reverse transcriptase substrate-induced conformational changes and the mechanism of inhibition by nonnucleoside inhibitors. K Rittinger, G Divita, R S Goody Proceedings of the National Academy of Sciences of the United States of America 1995 new
Head-on collision between a DNA replication apparatus and RNA polymerase transcription complex. B Liu, B M Alberts Science 1995 complete
DnaX complex of Escherichia coli DNA polymerase III holoenzyme. The chi psi complex functions by increasing the affinity of tau and gamma for delta.delta' to a physiologically relevant range. M W Olson, H Garry Dallmann, Charles S McHenry The Journal of biological chemistry 1995 pols set
Polymerase structures and function: variations on a theme? Catherine M Joyce, Thomas A Steitz J Bacteriol 1995 new
The rapid dissociation of the T4 DNA polymerase holoenzyme when stopped by a DNA hairpin helix. A model for polymerase release following the termination of each Okazaki fragment. K J Hacker, B M Alberts The Journal of biological chemistry 1994 complete
Mutagenesis of a highly conserved lysine 340 of the PRD1 DNA polymerase. Wenge Zhu, M C Leavitt, G Jung, J Ito Biochimica et biophysica acta 1994 new
DNA found in human immunodeficiency virus type 1 particles may not be required for infectivity. E.J. Arts, J Mak, Lawrence Kleiman, Mark A. Wainberg The Journal of general virology 1994 pols set
Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP. H Pelletier, M R Sawaya, A Kumar, Samuel H Wilson, J Kraut Science 1994 new
Establishment of a human malignant T lymphoma cell line carrying retrovirus-like particles with RT activity. X Y Lan, Y Zeng, D Zhang, M L Hong, D X Wang, Y L Zhang, Z J Feng, M H Tang, B Z Feng Biomedical and environmental sciences : BES 1994 new
Mechanism of action of acyclic nucleoside phosphonates against herpes virus replication. Johan Neyts, Erik De Clercq Biochemical pharmacology 1994 new
holE, the gene coding for the theta subunit of DNA polymerase III of Escherichia coli: characterization of a holE mutant and comparison with a dnaQ (epsilon-subunit) mutant. S C Slater, M R Lifsics, Mike E O'Donnell, R Maurer Journal of bacteriology 1994 pols set
2.2 A resolution structure of the amino-terminal half of HIV-1 reverse transcriptase (fingers and palm subdomains). Torsten Unge, S Knight, R Bhikhabhai, S Lövgren, Z Dauter, K Wilson, B Strandberg Structure (London, England : 1993) 1994 topics set
DNA polymerase delta is required for base excision repair of DNA methylation damage in Saccharomyces cerevisiae. A Blank, Baek Kim, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1994 pols set
Replication of bovine papillomavirus type 1 origin-containing DNA in crude extracts and with purified proteins. F Müller, Yeon-Soo Seo, Jerard Hurwitz The Journal of biological chemistry 1994 new
The slow dissociation of the T4 DNA polymerase holoenzyme when stalled by nucleotide omission. An indication of a highly processive enzyme. K J Hacker, B M Alberts The Journal of biological chemistry 1994 partial results
On the 'active' molecules of DNA-polymerase beta in aging rat brain. Kalluri Subba Rao, D Vinay Kumar, M S Bhaskar, G Sripad Biochem Mol Biol Int 1994 new
Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanism. M R Sawaya, H Pelletier, A Kumar, Samuel H Wilson, J Kraut Science 1994 topics set
Mutating the "primer grip" of p66 HIV-1 reverse transcriptase implicates tryptophan-229 in template-primer utilization. P S Jacques, B M Wöhrl, M Ottmann, J L Darlix, Stuart F J Le Grice The Journal of biological chemistry 1994 pols set
Properties of tyrosine 766-->serine mutant of Escherichia coli DNA polymerase I: template-specific effects. S D Desai, V N Pandey, Mukund J Modak Biochemistry 1994 pols set
A single mutation in bacteriophage T4 DNA polymerase (A737V, tsL141) decreases its processivity as a polymerase and increases its processivity as a 3'-->5' exonuclease. P Spacciapoli, Nancy G Nossal The Journal of biological chemistry 1994 partial results
Identification of a pharmacophore for nucleoside analog inhibitors directed at HIV-1 reverse transcriptase. M A Fisher, P N Yadav, J Yadav, D Kristol, Edward Arnold, Mukund J Modak Journal of molecular recognition : JMR 1994 pols set
Rates of spontaneous mutation in bacteriophage T4 are independent of host fidelity determinants. M E Santos, J W Drake Genetics 1994 complete
An explanation for lagging strand replication: polymerase hopping among DNA sliding clamps. P T Stukenberg, J Turner, Mike E O'Donnell Cell 1994 new
A 17S multiprotein form of murine cell DNA polymerase mediates polyomavirus DNA replication in vitro. Y Wu, Robert Hickey, K Lawlor, P Wills, F Yu, H Ozer, R Starr, J Y Quan, M Lee, Linda Malkas J Cell Biochem 1994 new
Fidelity of HIV-1 reverse transcriptase copying a hypervariable region of the HIV-1 env gene. J Ji, Lawrence A Loeb Virology 1994 pols set
Site-directed mutagenesis of HIV reverse transcriptase to probe enzyme processivity and drug binding. William A Beard, Samuel H Wilson Current opinion in biotechnology 1994 pols set
Template 2-chloro-2'-deoxyadenosine monophosphate inhibits in vitro DNA synthesis. P Hentosh, P Grippo Mol Pharmacol 1994 topics set
A computer-assisted analysis of conserved residues in the three-dimensional structures of the polymerase domains of Escherichia coli DNA polymerase I and HIV-1 reverse transcriptase. P N Yadav, J S Yadav, Edward Arnold, Mukund J Modak The Journal of biological chemistry 1994 pols set
Pre-steady-state kinetic analysis of sequence-dependent nucleotide excision by the 3'-exonuclease activity of bacteriophage T4 DNA polymerase. Linda B Bloom, M R Otto, R Eritja, Linda J Reha-Krantz, Myron F Goodman, J M Beechem Biochemistry 1994 pols set
Comparison of cord blood and peripheral blood mononuclear cells as targets for viral isolation and drug sensitivity studies involving human immunodeficiency virus type 1. H Salomon, A Belmonte, K Nguyen, Z Gu, M Gelfand, Mark A. Wainberg Journal of clinical microbiology 1994 new
Studies on primer binding of HIV-1 reverse transcriptase using a fluorescent probe. M D Delahunty, Samuel H Wilson, R L Karpel Journal of molecular biology 1994 pols set
Reactive oxygen species in tumorigenesis. D I Feig, T M Reid, Lawrence A Loeb Cancer research 1994 new
DNA repair gene RAD3 of S. cerevisiae is essential for transcription by RNA polymerase II. S N Guzder, H Qiu, C H Sommers, P Sung, Louise Prakash, Satya Prakash Nature 1994 new
RAD25 is a DNA helicase required for DNA repair and RNA polymerase II transcription. S N Guzder, P Sung, V Bailly, Louise Prakash, Satya Prakash Nature 1994 new
Identification and elimination of DNA sequences in Taq DNA polymerase. M S Hughes, L A Beck, R A Skuce J Clin Microbiol 1994 pols set
Expression and localization of human oxytocin receptor mRNA and its protein in chorion and decidua during parturition. Masaharu Takemura, T Kimura, S Nomura, Y Makino, T Inoue, T Kikuchi, Y Kubota, Y Tokugawa, T Nobunaga, S Kamiura The Journal of clinical investigation 1994 new
Nucleotide insertion and primer extension at abasic template sites in different sequence contexts. Myron F Goodman, H Cai, Linda B Bloom, R Eritja Annals of the New York Academy of Sciences 1994 pols set
3'-->5' exonuclease active site of phi 29 DNA polymerase. Evidence favoring a metal ion-assisted reaction mechanism. J A Esteban, M S Soengas, Margarita Salas, Luis Blanco The Journal of biological chemistry 1994 pols set
Looking backward on a century of mutation research. John W Drake Environ Mol Mutagen 1994 complete
In situ transcription with Tth DNA polymerase and fluorescent nucleotides. H Chang J Immunol Methods 1994 new
Subunit specificity of mutations that confer resistance to nonnucleoside inhibitors in human immunodeficiency virus type 1 reverse transcriptase. Paul L Boyer, Jianping Ding, Edward Arnold, Stephen H Hughes Antimicrobial agents and chemotherapy 1994 pols set
Sulfate- and sialic acid-containing glycolipids inhibit DNA polymerase alpha activity. C M Simbulan, T Taki, K Tamiya-Koizumi, Motoshi Suzuki, E Savoysky, M Shoji, Shonen Yoshida Biochimica et biophysica acta 1994 new
Genetic identification and nucleotide sequence of the DNA polymerase gene of African swine fever virus. A Martins, G Ribeiro, M I Marques, J V Costa Nucleic acids research 1994 new
The role of DNA polymerase in the production of UV-induced mutations in an in vitro model system. D Sagher, E Turkington, S Acharya, Bernard Strauss Ann N Y Acad Sci 1994 new
Identification of novel mutations that confer drug resistance in the human immunodeficiency virus polymerase gene. Z Gu, Q Gao, H Fang, Michael A. Parniak, Bluma G Brenner, Mark A. Wainberg Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1994 pols set
Isolation of a DNA polymerase I (polA) mutant of Rhizobium leguminosarum that has significantly reduced levels of an IncQ-group plasmid. S F Crank, J A Downie Mol Gen Genet 1994 new
Structural and functional organization of herpes simplex virus DNA polymerase investigated by limited proteolysis. Klaus Weisshart, A A Kuo, Charles B C Hwang, K Kumura, Donald M Coen The Journal of biological chemistry 1994 new
Interaction of poly(ADP-ribose)polymerase with DNA polymerase alpha. Shonen Yoshida, C M Simbulan Mol Cell Biochem 1994 pols set
Molecular modeling of RNA polymerase II mutations onto DNA polymerase I. W J Kim, L P Burke, M A Mortin Journal of molecular biology 1994 pols set
Multiple roles for DNA polymerase I in establishment and replication of the promiscuous plasmid pLS1. A Díaz, S A Lacks, P López Molecular microbiology 1994 new
DNA polymerase alpha as an independent prognostic parameter in non-small cell lung cancer--an immunohistochemical study. M Tateishi, T Ishida, M Hamatake, Y Fukuyama, S Kodono, K Sugimachi, K Akazawa Eur J Surg Oncol 1994 new
Binding specificity of T4 DNA polymerase to RNA. Andrey R Pavlov, Jim D Karam The Journal of biological chemistry 1994 complete
[DNA fragment DARC146 from a complex form of DNA polymerase alpha contains several nuclear protein binding segments]. V V Luniak, N A Timchenko Mol Biol (Mosk) 1994 new
Genetic dissection of T4 DNA polymerase structure-function relationships Book: Molecular Biology of Bacteriophage T4 1994 complete
Spontaneous mutation in Escherichia coli containing the dnaE911 DNA polymerase antimutator allele. A R Oller, Roel M Schaaper Genetics 1994 new
Further characterization of the interaction between the Epstein-Barr virus DNA polymerase catalytic subunit and its accessory subunit with regard to the 3'-to-5' exonucleolytic activity and stability of initiation complex at primer terminus. Tatsuya Tsurumi, T Daikoku, Yoshitaka Nishiyama J Virol 1994 new
DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period. H Kimura, N Nozaki, K Sugimoto The EMBO journal 1994 new
Susceptibilities of human immunodeficiency virus type 1 enzyme and viral variants expressing multiple resistance-engendering amino acid substitutions to reserve transcriptase inhibitors. V W Byrnes, E A Emini, W A Schleif, J H Condra, C L Schneider, W J Long, J A Wolfgang, D J Graham, L Gotlib, A J Schlabach Antimicrob Agents Chemother 1994 topics set
Allosteric interaction of a herpes simplex viral thymidine kinase with host DNA polymerase alpha in mouse LP1-1 cells. C G Kim, E Y Shim, J E Lee, Y K Jang, C G Lee, S D Park Biochem Mol Biol Int 1994 new
The yeast Saccharomyces cerevisiae DNA polymerase IV: possible involvement in double strand break DNA repair. S H Leem, P A Ropp, Akio Sugino Nucleic acids research 1994 pols set
Novel mutation (V75T) in human immunodeficiency virus type 1 reverse transcriptase confers resistance to 2',3'-didehydro-2',3'-dideoxythymidine in cell culture. S F Lacey, Brendan A Larder Antimicrobial agents and chemotherapy 1994 pols set
Melting of a DNA helix terminus within the active site of a DNA polymerase. R A Hochstrasser, T E Carver, L C Sowers, David P Millar Biochemistry 1994 new
Identification and analysis of a template-primer (ds-DNA) binding cleft in E. coli DNA polymerase I: an electrostatic potential contour pattern of the modeled structure. P N Yadav, Mukund J Modak, J S Yadav J Mol Recognit 1994 pols set
The Bacteriophage T4 DNA Replication Fork Book: Molecular Biology of Bacteriophage T4 1994 complete
Stimulation of calf thymus DNA polymerase alpha activity by nucleolar protein B23. Masaharu Takemura, N Ohta, Yasuhiro Furuichi, Tomonori Takahashi, Shonen Yoshida, M O Olson, H Umekawa Biochem Biophys Res Commun 1994 new
Interaction of herpes simplex virus type 1 DNA polymerase and the UL42 accessory protein with a model primer template. J Gottlieb, M D Challberg J Virol 1994 new
Genotypic and phenotypic analysis of human immunodeficiency virus type 1 isolates from patients on prolonged stavudine therapy. P F Lin, H Samanta, R E Rose, A K Patick, J Trimble, C M Bechtold, D R Revie, N C Khan, M E Federici, H Li J Infect Dis 1994 new
Hyperrecombination in pneumococcus: A/G to C.G repair and requirement for DNA polymerase I. F Pasta, M A Sicard Mutation research 1994 new
Development and significance of nucleoside drug resistance in infection caused by the human immunodeficiency virus type 1. M Smith, H Salomon, Mark A. Wainberg Clinical and investigative medicine. Médecine clinique et experimentale 1994 pols set
Spatial relationship between polymerase and exonuclease active sites of phage T4 DNA polymerase enzyme. V Gopalakrishnan, Stephen J Benkovic The Journal of biological chemistry 1994 topics set
Regulation of human DNA polymerase delta during the cell cycle. X R Zeng, H Hao, Yanan Jiang, Marietta Y W T Lee The Journal of biological chemistry 1994 pols set
Overproduction of Thermus aquaticus DNA polymerase and its structural analysis by ion-spray mass spectrometry. Yoshizumi Ishino, Takayuki Ueno, M Miyagi, Takashi Uemori, M Imamura, S Tsunasawa, Ikunoshin Kato J Biochem 1994 topics set
Role of the carboxy terminus of herpes simplex virus type 1 DNA polymerase in its interaction with UL42. Howard S Marsden, Mary C Murphy, G L McVey, K A MacEachran, A M Owsianka, N D Stow The Journal of general virology 1994 new
A beta-like DNA polymerase from the mitochondrion of the trypanosomatid Crithidia fasciculata. A F Torri, Thomas A Kunkel, Paul T Englund The Journal of biological chemistry 1994 new
The human DNA polymerase beta gene structure. Evidence of alternative splicing in gene expression. Yau-Jan Chyan, S Ackerman, N S Shepherd, O W McBride, S G Widen, Samuel H Wilson, T G Wood Nucleic acids research 1994 pols set
Role of lysine 758 of Escherichia coli DNA polymerase I as assessed by site-directed mutagenesis. V N Pandey, Neerja Kaushik, Mukund J Modak The Journal of biological chemistry 1994 pols set
The 'helix clamp' in HIV-1 reverse transcriptase: a new nucleic acid binding motif common in nucleic acid polymerases. T Hermann, T Meier, Matthias Götte, H Heumann Nucleic acids research 1994 pols set
Physiological concentrations of purines and pyrimidines. T W Traut Mol Cell Biochem 1994 new
Comparison of deoxyoligonucleotide and tRNA(Lys-3) as primers in an endogenous human immunodeficiency virus-1 in vitro reverse transcription/template-switching reaction. E.J. Arts, Xincang Li, Z Gu, Lawrence Kleiman, Michael A. Parniak, Mark A. Wainberg The Journal of biological chemistry 1994 pols set
Initiation of DNA replication by simian virus 40 T antigen is inhibited by the p107 protein. A A Amin, Y Murakami, Jerard Hurwitz The Journal of biological chemistry 1994 new
Mature reverse transcriptase (p66/p51) is responsible for low levels of viral DNA found in human immunodeficiency virus type 1 (HIV-1). E.J. Arts, J Mak, Lawrence Kleiman, Mark A. Wainberg Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1994 pols set
Involvement of Escherichia coli DNA polymerase II in response to oxidative damage and adaptive mutation. M Escarceller, J Hicks, G Gudmundsson, G Trump, D Touati, S Lovett, Patricia L Foster, K McEntee, Myron F Goodman J Bacteriol 1994 pols set
2.3 A crystal structure of the catalytic domain of DNA polymerase beta. J F Davies, R J Almassy, Z Hostomska, R A Ferre, Z Hostomsky Cell 1994 new
Primer-terminus stabilization at the psi 29 DNA polymerase active site. Mutational analysis of conserved motif TX2GR. Juan Méndez, Luis Blanco, José María Lázaro, Margarita Salas The Journal of biological chemistry 1994 partial results
The K65R mutant reverse transcriptase of HIV-1 cross-resistant to 2', 3'-dideoxycytidine, 2',3'-dideoxy-3'-thiacytidine, and 2',3'-dideoxyinosine shows reduced sensitivity to specific dideoxynucleoside triphosphate inhibitors in vitro. Z Gu, Ronald S Fletcher, E.J. Arts, Mark A. Wainberg, Michael A. Parniak The Journal of biological chemistry 1994 pols set
Affinity modification of human immunodeficiency virus reverse transcriptase and DNA template by photoreactive dCTP analogs. S V Doronin, M I Dobrikov, M Buckle, P Roux, H Buc, Olga I Lavrik FEBS letters 1994 pols set
Design of structure-based reverse transcriptase inhibitors. I Kang, Jing-Houng Wang The Journal of biological chemistry 1994 pols set
Assembly of DNA polymerase delta and epsilon holoenzymes depends on the geometry of the DNA template. L M Podust, Vladimir N Podust, C Floth, Ulrich Hübscher Nucleic acids research 1994 topics set
A unique subpopulation of murine DNA polymerase alpha/primase specifically interacts with polyomavirus T antigen and stimulates DNA replication. K Moses, C Prives Molecular and cellular biology 1994 new
Poly (ADP-ribose) polymerase inhibits DNA replication by human replicative DNA polymerase alpha, delta and epsilon in vitro. Toshihiko Eki FEBS letters 1994 new
Coordination of leading and lagging strand DNA synthesis at the replication fork of bacteriophage T7. Zeger Debyser, Stanley Tabor, Charles C Richardson Cell 1994 pols set
Redesignation of the RNase D activity associated with retroviral reverse transcriptase as RNase H. Z Hostomsky, Stephen H Hughes, S P Goff, Stuart F J Le Grice Journal of virology 1994 new
Vaccinia virus DNA polymerase. In vitro analysis of parameters affecting processivity. W F McDonald, Paula Traktman The Journal of biological chemistry 1994 topics set
Resistance to 2',3'-dideoxycytidine conferred by a mutation in codon 65 of the human immunodeficiency virus type 1 reverse transcriptase. D Zhang, A M Caliendo, J J Eron, K M DeVore, J C Kaplan, M S Hirsch, R T D'Aquila Antimicrobial agents and chemotherapy 1994 pols set
Effect of single DNA lesions on in vitro replication with DNA polymerase III holoenzyme. Comparison with other polymerases. P Belguise-Valladier, Hisaji Maki, M Sekiguchi, Robert P P Fuchs Journal of molecular biology 1994 new
Targeting of DNA polymerase to the adenovirus origin of DNA replication by interaction with nuclear factor I. M T Armentero, M Horwitz, N Mermod Proceedings of the National Academy of Sciences of the United States of America 1994 new
DNA polymerase delta is involved in the cellular response to UV damage in human cells. X R Zeng, Yanan Jiang, S J Zhang, H Hao, Marietta Y W T Lee The Journal of biological chemistry 1994 new
Molecular cloning and expression of the Saccharomyces cerevisiae RFC3 gene, an essential component of replication factor C. Xincang Li, Peter M J Burgers Proceedings of the National Academy of Sciences of the United States of America 1994 topics set
Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. H Gu, J D Marth, P C Orban, H Mossmann, Klaus Rajewsky Science 1994 new
Sphingosine inhibits the synthesis of RNA primers by primase in vitro. C M Simbulan, K Tamiya-Koizumi, Motoshi Suzuki, M Shoji, T Taki, Shonen Yoshida Biochemistry 1994 new
Drosophila DNA polymerase delta. Purification and characterization. N Aoyagi, S Matsuoka, A Furunobu, Akio Matsukage, Kengo Sakaguchi The Journal of biological chemistry 1994 partial results
The essential in vivo function of the herpes simplex virus UL42 protein correlates with its ability to stimulate the viral DNA polymerase in vitro. P J Reddig, L A Grinstead, S J Monahan, P A Johnson, Deborah S Parris Virology 1994 new
PCR amplification of up to 35-kb DNA with high fidelity and high yield from lambda bacteriophage templates. Wayne M Barnes Proceedings of the National Academy of Sciences of the United States of America 1994 pols set
DNA polymerase II of Escherichia coli in the bypass of abasic sites in vivo. I Tessman, M A Kennedy Genetics 1994 pols set
Catalytic properties of DNA polymerase alpha activity associated with the heart-stabilized nuclear matrix prepared from HeLa S3 cells. A M Martelli, R Bareggi, P Narducci Cell Biochem Funct 1994 new
Characterization of the mitochondrial DNA polymerase from Saccharomyces cerevisiae. S Sen, S Mukhopadhyay, J Wetzel, T K Biswas Acta Biochim Pol 1994 pols set
Sensitivity of (138 Glu-->Lys) mutated human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) to HIV-1-specific RT inhibitors. Jan Balzarini, Jörg-Peter Kleim, G Riess, María-José Camarasa, Erik De Clercq, Anna Karlsson Biochemical and biophysical research communications 1994 pols set
Inhibition of Klenow fragment DNA polymerase on double-helical templates by oligonucleotide-directed triple-helix formation. J G Hacia, P B Dervan, B J Wold Biochemistry 1994 pols set
[Inhibitory analysis of DNA polymerase of herpes simplex type 1]. M K Kukhanova, E V Kuznetsova, M V Ias'ko, B O'Hara, J Bekker, J Morin, Y a Gluzman Mol Biol (Mosk) 1994 new
Aphidicolin inhibits in vitro the activity of pseudorabies virus (PRV) DNA polymerase and in vivo the viral proliferation. A Verri, Giovanni Maga, Silvio Spadari, W Ponti, S Strosselli, L Bonizzi, M Rocchi, G Poli, Federico Focher In Vivo 1994 new
Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA. T S Krishna, Xiang-Peng Kong, S Gary, Peter M J Burgers, John Kuriyan Cell 1994 topics set
Cardiac mitochondrial DNA polymerase-gamma is inhibited competitively and noncompetitively by phosphorylated zidovudine. W Lewis, J F Simpson, R R Meyer Circ Res 1994 new
Assignments of 1H, 15N, and 13C resonances for the backbone and side chains of the N-terminal domain of DNA polymerase beta. Determination of the secondary structure and tertiary contacts. D Liu, Eugene F DeRose, Rajendra Prasad, Samuel H Wilson, Gregory P Mullen Biochemistry 1994 pols set
A biological method for examining the effect of codon changes in a conserved region of DNA polymerase. F M DeFilippes BioTechniques 1994 new
Rescue of a failed polymerase chain reaction catalyzed by vent or deep vent DNA polymerase with 10% dimethyl sulfoxide. S L Berger Anal Biochem 1994 new
DNA polymerase alpha-primase complex from the silk glands of the non-mulberry silkworm Philosamia ricini. S Niranjanakumari, K P Gopinathan Biochem J 1994 topics set
A functional assay for Taq DNA polymerase in PCR. M Wada, C Klein, J Schell, B Reiss BioTechniques 1994 pols set
Reverse chemical mutagenesis: identification of the mutagenic lesions resulting from reactive oxygen species-mediated damage to DNA. D I Feig, L C Sowers, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1994 new
Analysis of inhibitors of bacteriophage T4 DNA polymerase. N N Khan, Linda J Reha-Krantz, George E Wright Nucleic acids research 1994 complete
Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer. Jianhong Wang, S J Smerdon, J Jäger, L A Kohlstaedt, P A Rice, J M Friedman, Thomas A Steitz Proceedings of the National Academy of Sciences of the United States of America 1994 new
Efficient second-strand cDNA synthesis using T7 DNA polymerase. M Bodescot, O Brison DNA Cell Biol 1994 pols set
Involvement of DNA polymerase delta and/or epsilon in joining UV-induced DNA single strand breaks in human fibroblasts (comparison of effects of butylphenyldeoxyguanosine with aphidicolin). K Yamada, R Itoh Biochimica et biophysica acta 1994 new
Murine temperature-sensitive DNA polymerase alpha mutant displays a diminished capacity to stimulate DNA synthesis in senescent human fibroblast nuclei in heterokaryons at the nonpermissive condition. W R Pendergrass, A C Saulewicz, Fumio Hanaoka, Thomas H Norwood Journal of cellular physiology 1994 new
New tetrahydroimidazo[4,5,1-jk][1,4]-benzodiazepin-2(1H)-one and -thione derivatives are potent inhibitors of human immunodeficiency virus type 1 replication and are synergistic with 2',3'-dideoxynucleoside analogs. Rudi Pauwels, Koen Andries, Zeger Debyser, Michael J Kukla, Dominique Schols, H J Breslin, R Woestenborghs, J Desmyter, M A Janssen, Erik De Clercq Antimicrobial agents and chemotherapy 1994 pols set
Mutagenicity and pausing of HIV reverse transcriptase during HIV plus-strand DNA synthesis. J Ji, Jean-Sébastien Hoffmann, L Loeb Nucleic acids research 1994 pols set
No discrete complexes containing DNA polymerase alpha activity can be solubilized from the heat-stabilized nuclear matrix prepared from HeLa S3 cells. A M Martelli, L Cocco Cell Biochem Funct 1994 new
New developments in the chemotherapy of lentivirus (human immunodeficiency virus) infections: sensitivity/resistance of HIV-1 to non-nucleoside HIV-1-specific inhibitors. Erik De Clercq Annals of the New York Academy of Sciences 1994 pols set
Identification of a point mutation in the cDNA of the catalytic subunit of DNA polymerase alpha from a temperature-sensitive mouse FM3A cell line. M Izumi, Hiroshi Miyazawa, S Harakawa, F Yatagai, Fumio Hanaoka The Journal of biological chemistry 1994 new
An ATF/CREB site is the major regulatory element in the human herpesvirus 6 DNA polymerase promoter. A D Agulnick, J R Thompson, R P Ricciardi J Virol 1994 new
DNA polymerase beta gene mutation in human prostate cancer. Y Dobashi, T Shuin, H Tsuruga, H Uemura, S Torigoe, Y Kubota Cancer research 1994 pols set
Motif A of bacteriophage T4 DNA polymerase: role in primer extension and DNA replication fidelity. Isolation of new antimutator and mutator DNA polymerases. Linda J Reha-Krantz, R L Nonay The Journal of biological chemistry 1994 complete
The incN plasmid replicon: two pathways of DNA polymerase I-independent replication. H Y Kim, S K Banerjee, V N Iyer J Bacteriol 1994 new
Biochemical characterization of a temperature-sensitive adenovirus DNA polymerase. H Chen, M Ramachandra, R Padmanabhan Virology 1994 new
Preclinical evaluation of MKC-442, a highly potent and specific inhibitor of human immunodeficiency virus type 1 in vitro. Masanori Baba, S Shigeta, S Yuasa, H Takashima, K Sekiya, M Ubasawa, Hiromichi Tanaka, T Miyasaka, R T Walker, Erik De Clercq Antimicrobial agents and chemotherapy 1994 pols set
Identification of mutations in DNA polymerase beta mRNAs from patients with Werner syndrome. Y Sadakane, K Maeda, Y Kuroda, K Hori Biochem Biophys Res Commun 1994 new
A new meiotic protein factor which enhances activity of meiotic DNA polymerase from Coprinus cinereus. K Gomi, Kengo Sakaguchi Biochem Biophys Res Commun 1994 new
T7 DNA polymerase requires unusual reaction conditions for blunt-ending activity. M Bodescot, O Brison Anal Biochem 1994 pols set
Strand displacement activity of the human immunodeficiency virus type 1 reverse transcriptase heterodimer and its individual subunits. M Hottiger, Vladimir N Podust, R L Thimmig, C McHenry, Ulrich Hübscher The Journal of biological chemistry 1994 pols set
[Epstein-Barr virus DNA polymerase complex]. Tatsuya Tsurumi Uirusu 1994 new
Mutants affecting nucleotide recognition by T7 DNA polymerase. M J Donlin, Kenneth A Johnson Biochemistry 1994 topics set
HIV resistance to reverse transcriptase inhibitors. Erik De Clercq Biochemical pharmacology 1994 pols set
DNA polymerase arrest by adducted trivalent chromium. L C Bridgewater, F C Manning, E S Woo, Steven R Patierno Mol Carcinog 1994 pols set
Rolling circle DNA replication in vitro by a complex of herpes simplex virus type 1-encoded enzymes. R Skaliter, I. Robert Lehman Proceedings of the National Academy of Sciences of the United States of America 1994 new
Amino acid sequence motifs essential to 3'-->5' exonuclease activity of Escherichia coli DNA polymerase II. Yoshizumi Ishino, Hiroshi Iwasaki, Ikunoshin Kato, Hideo Shinagawa The Journal of biological chemistry 1994 pols set
Terminal protein-primed DNA amplification. Luis Blanco, José María Lázaro, Miguel de Vega, Ana Bonnin, Margarita Salas Proceedings of the National Academy of Sciences of the United States of America 1994 partial results
Differential effect of p53 on the promoters of mouse DNA polymerase beta gene and proliferating-cell-nuclear-antigen gene. Masamitsu Yamaguchi, Y Hayashi, S Matsuoka, Tomosaburo Takahashi, Akio Matsukage European journal of biochemistry / FEBS 1994 new
Enhancement of X-ray toxicity in squamous cell carcinoma cell lines by DNA polymerase inhibitors. R Mustafi, D Heaton, W Brinkman, J L Schwartz Int J Radiat Biol 1994 new
Misincorporation of nucleotides by calf thymus DNA primase and elongation of primers containing multiple noncognate nucleotides by DNA polymerase alpha. R J Sheaff, Robert D Kuchta The Journal of biological chemistry 1994 new
Beta subunit of DNA polymerase III holoenzyme is induced upon ultraviolet irradiation or nalidixic acid treatment of Escherichia coli. Y Tadmor, M Bergstein, R Skaliter, H Shwartz, Zvi Livneh Mutation research 1994 pols set
Role of Pr160gag-pol in mediating the selective incorporation of tRNA(Lys) into human immunodeficiency virus type 1 particles. J Mak, M Jiang, Mark A. Wainberg, M L Hammarskjöld, D Rekosh, Lawrence Kleiman Journal of virology 1994 pols set
Effect of 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine on establishment of human immunodeficiency virus type 1 infection in cultured CD8+ lymphocytes. L Mercure, B J Brenner, D Phaneuf, C Tsoukas, Mark A. Wainberg Antimicrobial agents and chemotherapy 1994 pols set
Function and structure relationships in DNA polymerases. Catherine M Joyce, Thomas A Steitz Annu Rev Biochem 1994 topics set
Escherichia coli mutY-dependent mismatch repair involves DNA polymerase I and a short repair tract. J J Tsai-Wu, A L Lu Mol Gen Genet 1994 new
Crystallization of DNA polymerase II from Escherichia coli. W F Anderson, D B Prince, Hong Yu, K McEntee, Myron F Goodman Journal of molecular biology 1994 pols set
Use of single-turnover kinetics to study bulky adduct bypass by T7 DNA polymerase. J E Lindsley, Robert P P Fuchs Biochemistry 1994 pols set
Misincorporation and mispaired primer extension by human immunodeficiency virus reverse transcriptase. S Zinnen, J C Hsieh, P Modrich The Journal of biological chemistry 1994 pols set
Effect of DNA polymerase inhibitors on repair of gamma ray-induced DNA damage in proliferating (intact versus permeable) human fibroblasts: evidence for differences in the modes of action of aphidicolin and 1-beta-D-arabinofuranosylcytosine. R Mirzayans, L Enns, S Cubitt, K Karimian, B Radatus, M C Paterson Biochimica et biophysica acta 1994 pols set
Evidence that an archaeal alpha-like DNA polymerase has a modular organization of its associated catalytic activities. Francesca M Pisani, Mosè Rossi The Journal of biological chemistry 1994 new
DNA polymerase alpha overcomes an error-prone pause site in the presence of replication protein-A. Motoshi Suzuki, Shunji Izuta, Shonen Yoshida The Journal of biological chemistry 1994 new
Expression of functional proliferating-cell nuclear antigen from rice (Oryza sativa) in Escherichia coli. Activity in association with human DNA polymerase delta. Takehisa Matsumoto, S Hata, I Suzuka, Junji Hashimoto Eur J Biochem 1994 pols set
Bacteriophage T7 RNA polymerase and its active-site mutants. Kinetic, spectroscopic and calorimetric characterization. P A Osumi-Davis, N Sreerama, D B Volkin, C R Middaugh, R W Woody, A Y Woody Journal of molecular biology 1994 new
Inhibition of gastric cancer cell proliferation by antisense oligonucleotides targeting the messenger RNA encoding proliferating cell nuclear antigen. C Sakakura, A Hagiwara, Hajime Tsujimoto, K Ozaki, T Sakakibara, Takuji Oyama, M Ogaki, Tomosaburo Takahashi British journal of cancer 1994 new
Enzymatic properties of two mutants of reverse transcriptase of human immunodeficiency virus type 1 (tyrosine 181-->isoleucine and tyrosine 188-->leucine), resistant to nonnucleoside inhibitors. S Loya, M Bakhanashvili, R Tal, Stephen H Hughes, Paul L Boyer, A Hizi AIDS research and human retroviruses 1994 pols set
Comparative cytostatic activity of different antiherpetic drugs against herpes simplex virus thymidine kinase gene-transfected tumor cells. Jan Balzarini, C Bohman, R T Walker, Erik De Clercq Molecular pharmacology 1994 new
Resistance of HIV-1 reverse transcriptase against [2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2''-dioxide)] (TSAO) derivatives is determined by the mutation Glu138-->Lys on the p51 subunit. H Jonckheere, J M Taymans, Jan Balzarini, Sonsoles Velázquez, María-José Camarasa, J Desmyter, Erik De Clercq, J Anné The Journal of biological chemistry 1994 pols set
Beta sliding clamp dynamics within E. coli DNA polymerase III holoenzyme. Mike E O'Donnell Ann N Y Acad Sci 1994 pols set
Base incorporation and extension at a site-specific ethenocytosine by Escherichia coli DNA polymerase I Klenow fragment. D Simha, D Yadav, R W Rzepka, V A Palejwala, M Zafri Humayun Mutation research 1994 pols set
The catalytic properties of the reverse transcriptase of the lentivirus equine infectious anemia virus. T Rubinek, S Loya, M Shaharabany, Stephen H Hughes, Patrick K Clark, A Hizi European journal of biochemistry / FEBS 1994 pols set
Anti-human immunodeficiency virus activities of the beta-L enantiomer of 2',3'-dideoxycytidine and its 5-fluoro derivative in vitro. G Gosselin, Raymond F Schinazi, J P Sommadossi, C Mathé, M C Bergogne, A M Aubertin, A Kirn, J L Imbach Antimicrobial agents and chemotherapy 1994 pols set
Resistance pattern of human immunodeficiency virus type 1 reverse transcriptase to quinoxaline S-2720. Jan Balzarini, Anna Karlsson, C Meichsner, A Paessens, G Riess, Erik De Clercq, Jörg-Peter Kleim Journal of virology 1994 pols set
The effect of divalent nickel (Ni2+) on in vitro DNA replication by DNA polymerase alpha. Y E Chin, E T Snow, M D Cohen, N T Christie Cancer research 1994 new
Scientific hypothesis: a new strategy for the design of anti-protozoal drugs--DNA polymerase as a drug target. M Biñas, A M Johnson Appl Parasitol 1994 new
Functional characterization of partially purified Epstein-Barr virus DNA polymerase expressed in the baculovirus system. J C Lin, B K De, E C Mar Virus genes 1994 new
Characterization of the HeLa cell DNA polymerase alpha-associated Ap4A binding protein by photoaffinity labeling. M D Baxi, A G McLennan, J K Vishwanatha Biochemistry 1994 new
Cytomegalovirus DNA polymerase activity and an 80 kDa-associated polypeptide: a potential diagnostic tool for CMV disease. M I Hassan, M A Nokta, R B Pollard J Virol Methods 1994 new
Strand displacement synthesis capability of Moloney murine leukemia virus reverse transcriptase. S H Whiting, J J Champoux Journal of virology 1994 partial results
Mutational analysis of the fingers and palm subdomains of human immunodeficiency virus type-1 (HIV-1) reverse transcriptase. Paul L Boyer, Andrea L Ferris, Patrick K Clark, J Whitmer, P Frank, C Tantillo, Edward Arnold, Stephen H Hughes Journal of molecular biology 1994 pols set
Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance. C Tantillo, Jianping Ding, A Jacobo-Molina, R G Nanni, Paul L Boyer, Stephen H Hughes, Rudi Pauwels, Koen Andries, Paul A J Janssen, Edward Arnold Journal of molecular biology 1994 pols set
Interaction of DNA polymerase and DNA helicase within the bacteriophage T4 DNA replication complex. Leading strand synthesis by the T4 DNA polymerase mutant A737V (tsL141) requires the T4 gene 59 helicase assembly protein. P Spacciapoli, Nancy G Nossal The Journal of biological chemistry 1994 complete
Effects of DNA polymerase beta gene over-expressed in transgenic Drosophila on DNA repair and recombination. M A Yoo, W H Lee, H Y Ha, J R Ryu, Masamitsu Yamaguchi, K Fujikawa, Akio Matsukage, S Kondo, Y Nishida Idengaku zasshi 1994 new
Resistance of human immunodeficiency virus type 1 to acyclic 6-phenylselenenyl- and 6-phenylthiopyrimidines. M H Nguyen, Raymond F Schinazi, C Shi, N M Goudgaon, P M McKenna, John W Mellors Antimicrobial agents and chemotherapy 1994 pols set
Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during therapy. Douglas D Richman, D Havlir, J Corbeil, D Looney, C Ignacio, S A Spector, J Sullivan, S Cheeseman, K Barringer, D Pauletti Journal of virology 1994 pols set
Elevated DNA polymerase alpha, DNA polymerase beta, and DNA topoisomerase II in a melphalan-resistant rhabdomyosarcoma xenograft that is cross-resistant to nitrosoureas and topotecan. H S Friedman, M E Dolan, S H Kaufmann, O M Colvin, O W Griffith, R C Moschel, S C Schold, D D Bigner, F Ali-Osman Cancer research 1994 new
Relief of DNA polymerase stop(s) due to severity of secondary structure of single-stranded DNA template during DNA sequencing. R S Ranu Anal Biochem 1994 new
Human immunodeficiency virus 1 (HIV-1)-specific reverse transcriptase (RT) inhibitors may suppress the replication of specific drug-resistant (E138K)RT HIV-1 mutants or select for highly resistant (Y181C-->C181I)RT HIV-1 mutants. Jan Balzarini, Anna Karlsson, V V Sardana, E A Emini, María-José Camarasa, Erik De Clercq Proceedings of the National Academy of Sciences of the United States of America 1994 pols set
Solid-state and solution conformations of the potent HIV inhibitor, 4'-azidothymidine. H Maag, J T Nelson, J L Steiner, E J Prisbe J Med Chem 1994 new
Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine. Z Gu, Q Gao, H Fang, H Salomon, Michael A. Parniak, E Goldberg, J Cameron, Mark A. Wainberg Antimicrobial agents and chemotherapy 1994 pols set
Interaction of alpha-deoxyadenosine in template DNA with DNA polymerase. A novel mutational spectrum induced by alpha-deoxyadenosine. Hiroshi Ide, Yumiko Kimura Ann N Y Acad Sci 1994 new
Isolation, characterization, and kinetic properties of truncated forms of T4 DNA polymerase that exhibit 3'-5' exonuclease activity. T C Lin, G Karam, William H Konigsberg The Journal of biological chemistry 1994 complete
Buried surface analysis of HIV-1 reverse transcriptase p66/p51 heterodimer and its interaction with dsDNA template/primer. Jianping Ding, A Jacobo-Molina, C Tantillo, Xiaoqing Lu, R G Nanni, Edward Arnold Journal of molecular recognition : JMR 1994 pols set
Structure/function studies of human immunodeficiency virus type 1 reverse transcriptase. Alanine scanning mutagenesis of an alpha-helix in the thumb subdomain. William A Beard, S J Stahl, H R Kim, Katarzyna Bebenek, A Kumar, M P Strub, S P Becerra, Thomas A Kunkel, Samuel H Wilson The Journal of biological chemistry 1994 new
Characterization of HIV-1 strains isolated from patients treated with TIBO R82913. A-M Vandamme, Zeger Debyser, Rudi Pauwels, K De Vreese, P Goubau, M Youle, B Gazzard, P A Stoffels, G F Cauwenbergh, J Anne AIDS research and human retroviruses 1994 pols set
Purification and characterization of PRD1 DNA polymerase. Wenge Zhu, J Ito Biochimica et biophysica acta 1994 new
Characterization of the tryptophan fluorescence and hydrodynamic properties of rat DNA polymerase beta. Soon-Jong Kim, M S Lewis, Jay R Knutson, D K Porter, A Kumar, Samuel H Wilson Journal of molecular biology 1994 new
Osmolyte mediation of T7 DNA polymerase and plasmid DNA stability. M Thakar, A Bilenko, W J Becktel Biochemistry 1994 pols set
Escherichia coli DNA polymerase III holoenzyme footprints three helical turns of its primer. J A Reems, Charles S McHenry The Journal of biological chemistry 1994 pols set
Structural and functional homology between mammalian DNase IV and the 5'-nuclease domain of Escherichia coli DNA polymerase I. P Robins, D J Pappin, Richard D Wood, T Lindahl The Journal of biological chemistry 1994 pols set
The Oct-1 POU domain stimulates adenovirus DNA replication by a direct interaction between the viral precursor terminal protein-DNA polymerase complex and the POU homeodomain. F E Coenjaerts, J A van Oosterhout, Peter C van der Vliet The EMBO journal 1994 new
Secretion of thermostable DNA polymerase using a novel baculovirus vector. B S Mroczkowski, A Huvar, W Lernhardt, K Misono, K Nielson, B Scott The Journal of biological chemistry 1994 new
The cellular DNA polymerase alpha-primase is required for papillomavirus DNA replication and associates with the viral E1 helicase. P Park, W Copeland, Linjing Yang, T Wang, M R Botchan, I J Mohr Proceedings of the National Academy of Sciences of the United States of America 1994 new
Oxygen radical induced mutagenesis is DNA polymerase specific. D I Feig, Lawrence A Loeb Journal of molecular biology 1994 new
Rapid preparation of Thermus flavus DNA polymerase. R A Harrell, R P Hart PCR Methods Appl 1994 new
Comparison of three different crystal forms shows HIV-1 reverse transcriptase displays an internal swivel motion. J Jäger, S J Smerdon, Jianhong Wang, D C Boisvert, Thomas A Steitz Structure (London, England : 1993) 1994 pols set
The synthesis of nucleoside 5'-O-(1,1-dithiotriphosphates). A Okruszek, M Olesiak, Jan Balzarini Journal of medicinal chemistry 1994 pols set
Repression of regulatory factor for Drosophila DNA replication-related gene promoters by zerknüllt homeodomain protein. Fumiko Hirose, Masamitsu Yamaguchi, Akio Matsukage The Journal of biological chemistry 1994 new
The DNA polymerase genes of several HMU-bacteriophages have similar group I introns with highly divergent open reading frames. H Goodrich-Blair, D A Shub Nucleic acids research 1994 new
Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme. H Flores-Rozas, Zvi Kelman, F B Dean, Z Q Pan, J W Harper, S J Elledge, Mike E O'Donnell, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1994 new
Overexpression and purification of the vaccinia virus DNA polymerase. W F McDonald, Paula Traktman Protein Expr Purif 1994 pols set
Studies of gapped DNA substrate binding by mammalian DNA polymerase beta. Dependence on 5'-phosphate group. Rajendra Prasad, William A Beard, Samuel H Wilson The Journal of biological chemistry 1994 pols set
5-Hydroxypyrimidine deoxynucleoside triphosphates are more efficiently incorporated into DNA by exonuclease-free Klenow fragment than 8-oxopurine deoxynucleoside triphosphates. A A Purmal, Y W Kow, Susan S Wallace Nucleic acids research 1994 pols set
Restoration of the DNA damage resistance of Deinococcus radiodurans DNA polymerase mutants by Escherichia coli DNA polymerase I and Klenow fragment. P D Gutman, P Fuchs, K W Minton Mutation research 1994 pols set
A rapid and efficient one-tube PCR-based mutagenesis technique using Pfu DNA polymerase. V Picard, E Ersdal-Badju, A Lu, S C Bock Nucleic acids research 1994 pols set
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1. S J Smerdon, J Jäger, Jianhong Wang, L A Kohlstaedt, A J Chirino, J M Friedman, P A Rice, Thomas A Steitz Proceedings of the National Academy of Sciences of the United States of America 1994 topics set
Crystallization of 31 kDa C-terminal fragment of rat DNA polymerase beta. Y Shirakihara, Akio Matsukage, Y Nishimoto, T Date Journal of molecular biology 1994 new
DNA sequence effects on single base deletions arising during DNA polymerization in vitro by Escherichia coli Klenow fragment polymerase. F J Wang, L S Ripley Genetics 1994 pols set
A meiotic DNA polymerase from a mushroom, Agaricus bisporus. K Takami, S Matsuda, A Sono, Kengo Sakaguchi Biochem J 1994 topics set
Error-prone replication of repeated DNA sequences by T7 DNA polymerase in the absence of its processivity subunit. Thomas A Kunkel, Smita S Patel, Kenneth A Johnson Proceedings of the National Academy of Sciences of the United States of America 1994 partial results
How to overcome resistance of HIV-1 to HIV-1-specific reverse transcriptase inhibitors. Erik De Clercq AIDS (London, England) 1994 pols set
DNA polymerase III of Mycoplasma pulmonis: isolation and characterization of the enzyme and its structural gene, polC. Marjorie H Barnes, Paul M Tarantino, P Spacciapoli, Neal C Brown, Hong Yu, K Dybvig Molecular microbiology 1994 new
Photoaffinity labeling of DNA template-primer binding site in Escherichia coli DNA polymerase I. Identification of involved amino acids. V N Pandey, Neerja Kaushik, Mukund J Modak The Journal of biological chemistry 1994 pols set
Acidic carboxyl-terminal domain of gene 2.5 protein of bacteriophage T7 is essential for protein-protein interactions. Y T Kim, Charles C Richardson The Journal of biological chemistry 1994 new
TaqStart Antibody: "hot start" PCR facilitated by a neutralizing monoclonal antibody directed against Taq DNA polymerase. D E Kellogg, I Rybalkin, S Chen, N Mukhamedova, T Vlasik, P D Siebert, A Chenchik BioTechniques 1994 pols set
D-type cyclin-binding regions of proliferating cell nuclear antigen. S Matsuoka, Masamitsu Yamaguchi, Akio Matsukage The Journal of biological chemistry 1994 new
Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II. R Drapkin, J T Reardon, A Ansari, J C Huang, L Zawel, K Ahn, A Sancar, D Reinberg Nature 1994 new
Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does not. Paul L Boyer, C Tantillo, A Jacobo-Molina, R G Nanni, Jianping Ding, Edward Arnold, Stephen H Hughes Proceedings of the National Academy of Sciences of the United States of America 1994 topics set
Monoclonal antibodies prepared against the DNA polymerase from Thermus aquaticus are potent inhibitors of enzyme activity. E R Scalice, D J Sharkey, J L Daiss J Immunol Methods 1994 new
Evidence against DNA polymerase beta as a candidate gene for Werner syndrome. M Chang, G C Burmer, Joann B Sweasy, Lawrence A Loeb, S Edelhoff, C M Disteche, C E Yu, L Anderson, J Oshima, J Nakura Hum Genet 1994 new
Proofreading DNA: recognition of aberrant DNA termini by the Klenow fragment of DNA polymerase I. T E Carver, R A Hochstrasser, David P Millar Proceedings of the National Academy of Sciences of the United States of America 1994 pols set
DNA replication fidelity with 8-oxodeoxyguanosine triphosphate. Youri I Pavlov, Dana T Minnick, Shunji Izuta, Thomas A Kunkel Biochemistry 1994 new
A short-term clinical evaluation of L-697,661, a non-nucleoside inhibitor of HIV-1 reverse transcriptase. L-697,661 Working Group. M S Saag, E A Emini, O L Laskin, J Douglas, W I Lapidus, W A Schleif, R J Whitley, C Hildebrand, V W Byrnes, John C Kappes The New England journal of medicine 1993 pols set
DNA binding properties of the deoxyguanosine triphosphate triphosphohydrolase of Escherichia coli. S M Wurgler, Charles C Richardson The Journal of biological chemistry 1993 pols set
Deoxypyrimidine cluster mediates the priming by calf thymus DNA primase subunit. Motoshi Suzuki, Shunji Izuta, E Savoysky, T Sakurai, C Simbulan, M Tatebe, K Kojima, Shonen Yoshida Biochemistry and molecular biology international 1993 new
Ionization of bromouracil and fluorouracil stimulates base mispairing frequencies with guanine. Hong Yu, R Eritja, Linda B Bloom, Myron F Goodman The Journal of biological chemistry 1993 new
A general two-metal-ion mechanism for catalytic RNA. Thomas A Steitz, J A Steitz Proceedings of the National Academy of Sciences of the United States of America 1993 pols set
Sequential proton NMR resonance assignments, circular dichroism, and structural properties of a 50-residue substrate-binding peptide from DNA polymerase I. Gregory P Mullen, J B Vaughn, A S Mildvan Arch Biochem Biophys 1993 new
Age-related changes in expression and activity of DNA polymerase alpha: some effects of dietary restriction. Vinod K Srivastava, S Miller, M D Schroeder, R W Hart, D Busbee Mutation research 1993 new
Epstein-Barr virus (EBV) replication and expressions of EA-D (BMRF1 gene product), virus-specific deoxyribonuclease, and DNA polymerase in EBV-activated Akata cells. M Daibata, T Sairenji Virology 1993 new
Two DNA polymerases: HIV reverse transcriptase and the Klenow fragment of Escherichia coli DNA polymerase I. Thomas A Steitz, S Smerdon, J Jäger, Jianhong Wang, L A Kohlstaedt, J M Friedman, Lorena S Beese, P A Rice Cold Spring Harbor symposia on quantitative biology 1993 pols set
A meiotic DNA polymerase from Coprinus cinereus: further purification and characterization. S Matsuda, K Takami, A Sono, Kengo Sakaguchi Chromosoma 1993 new
Inhibition of immunopurified DNA polymerase-alpha from PA-3 prostate tumor cells by platinum (II) antitumor drugs. T J Kelley, S Moghaddas, R Bose, S Basu Cancer Biochem Biophys 1993 new
Purification and characterization of a new DNA polymerase from budding yeast Saccharomyces cerevisiae. A probable homolog of mammalian DNA polymerase beta. Kikuo Shimizu, C Santocanale, P A Ropp, M P Longhese, Paolo Plevani, G Lucchini, Akio Sugino The Journal of biological chemistry 1993 new
Identification, isolation, and overexpression of the gene encoding the psi subunit of DNA polymerase III holoenzyme. J R Carter, M A Franden, R Aebersold, Charles S McHenry J Bacteriol 1993 new
Isolation and characterization of DNA polymerase epsilon from the silk glands of Bombyx mori. S Niranjanakumari, K P Gopinathan The Journal of biological chemistry 1993 new
Isolation, sequencing and overexpression of the gene encoding the theta subunit of DNA polymerase III holoenzyme. J R Carter, M A Franden, R Aebersold, D R Kim, Charles S McHenry Nucleic acids research 1993 new
A DNA polymerase alpha-associated 56 kDa protein kinase. V M Peck, E W Gerner, A E Cress Biochem Biophys Res Commun 1993 new
Stimulation of DNA polymerase gamma by a mitochondrial single-strand DNA binding protein. R Genuario, T W Wong Cell Mol Biol Res 1993 new
A comparison of DNA polymerase alpha from untransformed and SV40-transformed human fibroblasts. Vinod K Srivastava, M D Schroeder, S M Miller, David L Busbee Int J Biochem 1993 new
A comparison of the effect of hyperthermia on DNA polymerase in hamster and human glioma cells. G P Raaphorst, M M Feeley, G L Chu, W C Dewey Int J Hyperthermia 1993 new
Compilation, alignment, and phylogenetic relationships of DNA polymerases. D K Braithwaite, J Ito Nucleic acids research 1993 new
Digestion of damaged DNA by the T7 DNA polymerase-exonuclease. D R Koehler, P C Hanawalt Biochem J 1993 pols set
Influence of 5'-nearest neighbors on the insertion kinetics of the fluorescent nucleotide analog 2-aminopurine by Klenow fragment. Linda B Bloom, M R Otto, J M Beechem, Myron F Goodman Biochemistry 1993 pols set
Sulphydryl groups in the template-primer-binding domain of murine leukaemia virus reverse transcriptase. Identification and functional analysis of cysteine-90. S Basu, A Basu, Mukund J Modak The Biochemical journal 1993 new
Misincorporation of ribonucleotides by DNA polymerase during in vitro DNA replication. Hiroshi Ide, R Yagi, T Yamaoka, Yumiko Kimura Nucleic Acids Symp Ser 1993 pols set
Hydroxyl radical footprint analysis of human immunodeficiency virus reverse transcriptase-template.primer complexes. W Metzger, T Hermann, O Schatz, Stuart F J Le Grice, H Heumann Proceedings of the National Academy of Sciences of the United States of America 1993 new
Isosteres of the DNA polymerase inhibitor aphidicolin as potential antiviral agents against human herpes viruses. D L Selwood, S R Challand, J N Champness, J Gillam, D K Hibberd, K S Jandu, D Lowe, M Pether, J Selway, G E Trantor J Med Chem 1993 new
Low levels of deoxynucleotides in peripheral blood lymphocytes: a strategy to inhibit human immunodeficiency virus type 1 replication. W Y Gao, A Cara, R C Gallo, F Lori Proceedings of the National Academy of Sciences of the United States of America 1993 new
Three distinct Southern blot hybridization patterns of HBV-DNA in the sera of HBV carriers. Masami Yamada, M Ishii, M Miura, Shusei Sato, A Kanno, H Ohori, T Toyota The Tohoku journal of experimental medicine 1993 pols set
Kinetic mechanism of the DNA-dependent DNA polymerase activity of human immunodeficiency virus reverse transcriptase. J C Hsieh, S Zinnen, P Modrich The Journal of biological chemistry 1993 pols set
The same mutation that encodes low-level human immunodeficiency virus type 1 resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine confers high-level resistance to the (-) enantiomer of 2',3'-dideoxy-3'-thiacytidine. Q Gao, Z Gu, Michael A. Parniak, J Cameron, Nick Cammack, C Boucher, Mark A. Wainberg Antimicrob Agents Chemother 1993 topics set
DNA polymerase III accessory proteins. IV. Characterization of chi and psi. H Xiao, Z Dong, Mike E O'Donnell The Journal of biological chemistry 1993 new
Humoral immune response to human cytomegalovirus DNA polymerase. M P Landini, T Lazzarotto, P F Ertl J Clin Microbiol 1993 pols set
Identification, molecular cloning and characterization of the gene encoding the chi subunit of DNA polymerase III holoenzyme of Escherichia coli. J R Carter, M A Franden, J A Lippincott, Charles S McHenry Mol Gen Genet 1993 pols set
[Recognition of primers, containing noncomplementary nucleotides and units, lacking bases, by the Klenow fragment of Escherichia coli DNA polymerase I]. T I Kolocheva, A S Levina, G A Nevinskiĭ Mol Biol (Mosk) 1993 pols set
Construction and characterization of a bacteriophage T4 DNA polymerase deficient in 3'-->5' exonuclease activity. M W Frey, Nancy G Nossal, T L Capson, Stephen J Benkovic Proceedings of the National Academy of Sciences of the United States of America 1993 complete
Conformational changes induced in herpes simplex virus DNA polymerase upon DNA binding. Klaus Weisshart, A A Kuo, George R Painter, L L Wright, Phillip A Furman, Donald M Coen Proceedings of the National Academy of Sciences of the United States of America 1993 new
Mutations in the C terminus of herpes simplex virus type 1 DNA polymerase can affect binding and stimulation by its accessory protein UL42 without affecting basal polymerase activity. Daniel J Tenney, P A Micheletti, J T Stevens, Robert K Hamatake, J T Matthews, A R Sanchez, W W Hurlburt, M Bifano, M G Cordingley J Virol 1993 new
The Epstein-Barr virus DNA polymerase transactivates the human immunodeficiency virus type 1 5' long terminal repeat. J C Lin Biochem Biophys Res Commun 1993 pols set
DNA polymerase III accessory proteins. III. holC and holD encoding chi and psi. H Xiao, R Crombie, Z Dong, R Onrust, Mike E O'Donnell The Journal of biological chemistry 1993 pols set
Mutational studies of human DNA polymerase alpha. Serine 867 in the second most conserved region among alpha-like DNA polymerases is involved in primer binding and mispair primer extension. Q Dong, William C Copeland, Teresa S-F Wang The Journal of biological chemistry 1993 pols set
Antiviral agents: characteristic activity spectrum depending on the molecular target with which they interact. Erik De Clercq Advances in virus research 1993 pols set
Adenovirus DNA polymerase is a phosphoprotein. M Ramachandra, R Nakano, P M Mohan, A B Rawitch, R Padmanabhan The Journal of biological chemistry 1993 new
Kinetics of different human immunodeficiency virus type 1 reverse transcriptases resistant to human immunodeficiency virus type 1-specific reverse transcriptase inhibitors. Zeger Debyser, K De Vreese, P P Knops-Gerrits, V Baekelandt, R Bhikhabhai, B Strandberg, Rudi Pauwels, J Anné, J Desmyter, Erik De Clercq Molecular pharmacology 1993 pols set
Interaction of proliferating cell nuclear antigen with yeast DNA polymerase delta. W C Brown, Judith L Campbell The Journal of biological chemistry 1993 pols set
Detection of hepatitis B virus DNA in HBsAg chronic carriers using a liquid phase molecular hybridization (Abbott HBV DNA) and the DNA polymerase assay: comparison of results. C Cornu Acta Virol 1993 new
[Cloning of the gene for thermostable Thermus aquaticus YT1 DNA polymerase and its expression in Escherichia coli]. L I Patrushev, A G Valiaev, P A Golovchenko, S V Vinogradov, M L Chikindas, V I Kiselev Mol Biol (Mosk) 1993 new
DNA polymerase epsilon: aphidicolin inhibition and the relationship between polymerase and exonuclease activity. C H Cheng, Robert D Kuchta Biochemistry 1993 new
DNA polymerase-beta from the pupal ovaries of Bombyx mori. S Niranjanakumari, K P Gopinathan Insect Biochem Mol Biol 1993 new
Immunopurified Rb protein inhibits SV40 T antigen-dependent stimulation of DNA polymerase alpha. E Savoysky, Motoshi Suzuki, C Simbulan, Katsuyuki Tamai, T Ohuchi, Tetsu Akiyama, Shonen Yoshida Oncogene 1993 new
Use of M13 ping-pong vectors and T4 DNA polymerase in oligodeoxynucleotide-directed mutagenesis. M M Waye Methods in enzymology 1993 pols set
HIV-1-specific RT inhibitors: highly selective inhibitors of human immunodeficiency virus type 1 that are specifically targeted at the viral reverse transcriptase. Erik De Clercq Medicinal research reviews 1993 pols set
Activity of the anti-HIV agent 9-(2-phosphonyl-methoxyethyl)-2,6-diaminopurine against cytomegalovirus in vitro and in vivo. Johan Neyts, F Stals, C Bruggeman, Erik De Clercq European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1993 pols set
Effect of reaction pH on the fidelity and processivity of exonuclease-deficient Klenow polymerase. Kristin A Eckert, Thomas A Kunkel The Journal of biological chemistry 1993 partial results
Nucleotide sequence of the Borrelia burgdorferi dnaN gene encoding the beta subunit of DNA polymerase III. I G Old, D Margarita, I Saint Girons Nucleic acids research 1993 new
Functional expression and characterization of the Epstein-Barr virus DNA polymerase catalytic subunit. Tatsuya Tsurumi, Atsushi Kobayashi, Katsuyuki Tamai, T Daikoku, R Kurachi, Yoshitaka Nishiyama J Virol 1993 pols set
Conditional infectivity of a human immunodeficiency virus matrix domain deletion mutant. C T Wang, Yongqing Zhang, J McDermott, E Barklis Journal of virology 1993 pols set
Characterization of the DNA-dependent ATPase and a DNA unwinding activity associated with the yeast DNA polymerase alpha complex. Esther E Biswas, C M Ewing, Subhasis B Biswas Biochemistry 1993 new
De novo synthesis of budding yeast DNA polymerase alpha and POL1 transcription at the G1/S boundary are not required for entrance into S phase. M Muzi Falconi, A Piseri, M Ferrari, G Lucchini, Paolo Plevani, Marco Foiani Proceedings of the National Academy of Sciences of the United States of America 1993 new
Knocking-out concentrations of HIV-1-specific inhibitors completely suppress HIV-1 infection and prevent the emergence of drug-resistant virus. Jan Balzarini, Anna Karlsson, María-Jesús Pérez-Pérez, María-José Camarasa, Erik De Clercq Virology 1993 pols set
Fidelity studies of the human DNA polymerase alpha. The most conserved region among alpha-like DNA polymerases is responsible for metal-induced infidelity in DNA synthesis. William C Copeland, N K Lam, Teresa S-F Wang The Journal of biological chemistry 1993 pols set
Effect of a template-located 2',2'-difluorodeoxycytidine on the kinetics and fidelity of base insertion by Klenow (3'-->5'exonuclease-) fragment. W E Schy, L W Hertel, J S Kroin, Linda B Bloom, Myron F Goodman, Frank C Richardson Cancer research 1993 pols set
Expression and purification of the HIV-1 reverse transcriptase using the baculovirus expression vector system. S Kawa, A Kumar, J S Smith, S P Becerra, William A Beard, Samuel H Wilson, E B Thompson Protein expression and purification 1993 pols set
Characterization of DNA polymerase alpha from untransformed and pSV3.neo-transformed human fibroblasts. Vinod K Srivastava, M D Schroeder, David L Busbee Int J Biochem 1993 new
In vivo species specificity of DNA polymerase alpha. S Francesconi, William C Copeland, Teresa S-F Wang Mol Gen Genet 1993 new
The role of the 70 kDa subunit of human DNA polymerase alpha in DNA replication. K L Collins, A A Russo, B Y Tseng, T J Kelly The EMBO journal 1993 pols set
DNA helicase associated with DNA polymerase alpha: isolation by a modified immunoaffinity chromatography. Esther E Biswas, P H Chen, Subhasis B Biswas Biochemistry 1993 new
Identification of residues in the single-stranded DNA-binding site of the 8-kDa domain of rat DNA polymerase beta by UV cross-linking. Rajendra Prasad, A Kumar, S G Widen, J R Casas-Finet, Samuel H Wilson The Journal of biological chemistry 1993 new
Enhancement of DNA polymerase beta activity in the pituitary gland by hormonal feedback. Akio Nagasaka, Shonen Yoshida, R Masunaga, S Kato, Motoko Kotake, Akira Nakai, T Kawabe, T Tsujimura, A Inagaki, K Iwase Horm Metab Res 1993 new
[Contribution of 3'---5'-exonuclease from rat liver nuclei in precision of DNA synthesis, catalyzed by mammalian DNA polymerase alpha]. Igor V Shevelev, T P Kravetskaia, O K Legina, S N Naryzhnyĭ, F V Perrino, V M Krutiakov Mol Biol (Mosk) 1993 pols set
Genetic characterization of the vaccinia virus DNA polymerase: cytosine arabinoside resistance requires a variable lesion conferring phosphonoacetate resistance in conjunction with an invariant mutation localized to the 3'-5' exonuclease domain. J A Taddie, Paula Traktman J Virol 1993 pols set
Mutational analysis of the human DNA polymerase alpha. The most conserved region in alpha-like DNA polymerases is involved in metal-specific catalysis. William C Copeland, Teresa S-F Wang The Journal of biological chemistry 1993 pols set
Conditional mutations in the yeast DNA primase genes affect different aspects of DNA metabolism and interactions in the DNA polymerase alpha-primase complex. M P Longhese, L Jovine, Paolo Plevani, G Lucchini Genetics 1993 new
Poly(ADP-ribose) polymerase stimulates DNA polymerase alpha by physical association. C M Simbulan, Motoshi Suzuki, Shunji Izuta, T Sakurai, E Savoysky, K Kojima, K Miyahara, Y Shizuta, Shonen Yoshida The Journal of biological chemistry 1993 new
Replication of the base pair 6-thioguanine/5-methyl-2-pyrimidine with the large Klenow fragment of Escherichia coli DNA polymerase I. H P Rappaport Biochemistry 1993 pols set
High-level expression, purification, and enzymatic characterization of full-length Thermus aquaticus DNA polymerase and a truncated form deficient in 5' to 3' exonuclease activity. F C Lawyer, S Stoffel, R K Saiki, S Y Chang, P A Landre, R D Abramson, D H Gelfand PCR Methods Appl 1993 partial results
Mechanisms of mutation by oxidative DNA damage: reduced fidelity of mammalian DNA polymerase beta. D I Feig, Lawrence A Loeb Biochemistry 1993 pols set
The DNA replication fork can pass RNA polymerase without displacing the nascent transcript. B Liu, M L Wong, R L Tinker, E P Geiduschek, B M Alberts Nature 1993 complete
DNA polymerase III accessory proteins. V. Theta encoded by holE. P S Studwell-Vaughan, Mike E O'Donnell The Journal of biological chemistry 1993 new
General antimutators are improbable. John W Drake Journal of molecular biology 1993 partial results
Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA. A Jacobo-Molina, Jianping Ding, R G Nanni, Arthur D Clark, Xiaoqing Lu, C Tantillo, R L Williams, G Kamer, Andrea L Ferris, Patrick K Clark Proceedings of the National Academy of Sciences of the United States of America 1993 pols set
Minute virus of mice-induced modification of the murine DNA polymerase alpha-primase complex permits the salt-induced dissociation of 12S DNA primase and 10S DNA polymerase alpha components. J S Gupta, E A Faust Biochem Mol Biol Int 1993 new
Sulfonic acid polymers are potent inhibitors of HIV-1 induced cytopathogenicity and the reverse transcriptases of both HIV-1 and HIV-2. G T Tan, A Wickramasinghe, S Verma, Stephen H Hughes, J M Pezzuto, Masanori Baba, P Mohan Biochimica et biophysica acta 1993 pols set
Analysis of nonnucleoside drug-resistant variants of human immunodeficiency virus type 1 reverse transcriptase. Paul L Boyer, M J Currens, James B McMahon, M R Boyd, Stephen H Hughes Journal of virology 1993 pols set
Multi-stage proofreading in DNA replication. R A Beckman, Lawrence A Loeb Quarterly reviews of biophysics 1993 new
Bacteriophage T7 gene 2.5 protein: an essential protein for DNA replication. Y T Kim, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 1993 new
HIV resistance to anti-viral drugs. Mark A. Wainberg, H Salomon, Bonnie Spira, L Mercure, J Wainberg, K Nagai, Z Bentwich, J Montaner Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1993 pols set
Generation and characterization of murine monoclonal antibodies reactive against N-terminal and other regions of HIV-1 reverse transcriptase. Xincang Li, E Amandoron, Mark A. Wainberg, Michael A. Parniak Journal of medical virology 1993 pols set
Resistance to antiviral inhibitors caused by the mutation S889A in the highly-conserved 885-GDTDS motif of the herpes simplex virus type 1 DNA polymerase. D I Dorsky, C Plourde Virology 1993 new
Functional interaction between Epstein-Barr virus DNA polymerase catalytic subunit and its accessory subunit in vitro. Tatsuya Tsurumi, T Daikoku, R Kurachi, Yoshitaka Nishiyama J Virol 1993 pols set
Inhibition of mammalian DNA polymerase-associated 3' to 5' exonuclease activity by 5'-monophosphates of 3'-azido-3'-deoxythymidine and 3'-amino-3'-deoxythymidine. E G Bridges, A Faraj, J P Sommadossi Biochem Pharmacol 1993 pols set
ATP-independent loading of the proliferating cell nuclear antigen requires DNA ends. Peter M J Burgers, B L Yoder The Journal of biological chemistry 1993 new
Crystallographic analyses of an active HIV-1 ribonuclease H domain show structural features that distinguish it from the inactive form. D Chattopadhyay, B C Finzel, S H Munson, D B Evans, S K Sharma, N A Strakalaitus, D P Brunner, F M Eckenrode, Z Dauter, C Betzel, H M Einspahr Acta Crystallogr D Biol Crystallogr 1993 topics set
Antiproliferative effect of DNA polymerase alpha antisense oligodeoxynucleotides on breast cancer cells. A Alama, R Meazza, F Barbieri, R Biassoni, M Mazzei, A Nicolin Exp Cell Res 1993 new
Absence of a role for DNA polymerase II in SOS-induced translesion bypass of phi X174. Y W Kow, G Faundez, S Hays, C A Bonner, Myron F Goodman, Susan S Wallace J Bacteriol 1993 pols set
DNA helicases associated with DNA polymerases from human cells. T Sakurai, Motoshi Suzuki, Shonen Yoshida Biochem Mol Biol Int 1993 new
[Highly specific inhibitors of human immunodeficiency virus type I that are particularly targeted at the reverse transcriptase]. Erik De Clercq, Robert Snoeck Pathologie-biologie 1993 new
Unusual regulation of expression of the herpes simplex virus DNA polymerase gene. K K Wobbe, P Digard, D Staknis, Donald M Coen J Virol 1993 new
Inhibition of visna virus replication by 2',3'-dideoxynucleosides and acyclic nucleoside phosphonate analogs. H Thormar, Jan Balzarini, Antonin Holy, J Jindrich, I Rosenberg, Zeger Debyser, J Desmyter, Erik De Clercq Antimicrobial agents and chemotherapy 1993 new
Molecular cloning of the cDNA for the catalytic subunit of human DNA polymerase epsilon. Tapio Kesti, H Frantti, Juhani E Syväoja The Journal of biological chemistry 1993 pols set
Sequences at the C-terminus of the herpes simplex virus type 1 UL30 protein are dispensable for DNA polymerase activity but not for viral origin-dependent DNA replication. N D Stow Nucleic acids research 1993 new
Rapid purification of high-activity Taq DNA polymerase. F G Pluthero Nucleic acids research 1993 pols set
Short gap-filling synthesis by DNA polymerase beta is processive. R K Singhal, Samuel H Wilson The Journal of biological chemistry 1993 partial results
Conformational coupling in DNA polymerase fidelity. Kenneth A Johnson Annual review of biochemistry 1993 new
Two regions of the herpes simplex virus type 1 UL42 protein are required for its functional interaction with the viral DNA polymerase. S J Monahan, T F Barlam, C S Crumpacker, Deborah S Parris J Virol 1993 new
The Escherichia coli DNA polymerase III holoenzyme contains both products of the dnaX gene, tau and gamma, but only tau is essential. A Blinkova, C Hervas, P T Stukenberg, R Onrust, M E O'Donnell, J R Walker J Bacteriol 1993 pols set
Genetic and biochemical studies of bacteriophage T4 DNA polymerase 3'-->5'-exonuclease activity. Linda J Reha-Krantz, R L Nonay The Journal of biological chemistry 1993 complete
Retroviral vector-mediated transduction of K-ras antisense RNA into human lung cancer cells inhibits expression of the malignant phenotype. Yongqing Zhang, T Mukhopadhyay, L A Donehower, R N Georges, J A Roth Human gene therapy 1993 new
Inhibition of the wheat germ DNA polymerase A activity by the antiviral drug HPA-23. H Aoyama, M B Jucá, Michel Castroviejo, Simon Litvak Plant Mol Biol 1993 new
Cloning of a mouse cDNA encoding DNA polymerase delta: refinement of the homology boxes. G Cullmann, R Hindges, M W Berchtold, Ulrich Hübscher Gene 1993 pols set
The extreme C terminus of herpes simplex virus DNA polymerase is crucial for functional interaction with processivity factor UL42 and for viral replication. P Digard, W R Bebrin, Klaus Weisshart, Donald M Coen J Virol 1993 new
[Isolation of DNA polymerase beta from human placenta and study of its substrate specificity]. T I Kolocheva, G A Nevinskiĭ Mol Biol (Mosk) 1993 new
Specific inhibition of the reverse transcriptase of human immunodeficiency virus type 1 and the chimeric enzymes of human immunodeficiency virus type 1 and type 2 by nonnucleoside inhibitors. A Hizi, R Tal, M Shaharabany, M J Currens, M R Boyd, Stephen H Hughes, James B McMahon Antimicrobial agents and chemotherapy 1993 pols set
Translesional synthesis on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene). Shinya Shibutani, L A Margulis, Nicholas E Geacintov, Arthur P Grollman Biochemistry 1993 pols set
Novel 8-base pair sequence (Drosophila DNA replication-related element) and specific binding factor involved in the expression of Drosophila genes for DNA polymerase alpha and proliferating cell nuclear antigen. Fumiko Hirose, Masamitsu Yamaguchi, H Handa, Y Inomata, Akio Matsukage The Journal of biological chemistry 1993 new
Nucleotide sequence and promoter-specific effect of a negative regulatory region located upstream of the mouse proliferating cell nuclear antigen gene. S Matsuoka, Masamitsu Yamaguchi, Y Hayashi, Akio Matsukage European journal of biochemistry / FEBS 1993 new
Infection of human monocyte-derived macrophages by human immunodeficiency virus mediated by cell-to-cell transmission. S St Luce, E Arts, R Geleziunas, S Bour, Mark A. Wainberg Journal of medical virology 1993 pols set
Characterization of a DNA polymerase from the hyperthermophile archaea Thermococcus litoralis. Vent DNA polymerase, steady state kinetics, thermal stability, processivity, strand displacement, and exonuclease activities. H Kong, R B Kucera, William E Jack The Journal of biological chemistry 1993 partial results
High-level resistance to (-) enantiomeric 2'-deoxy-3'-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase. Charles A B Boucher, Nick Cammack, P Schipper, Rob Schuurman, P Rouse, Mark A. Wainberg, J M Cameron Antimicrobial agents and chemotherapy 1993 new
Clinical correlates and molecular basis of HIV drug resistance. Mark A. Wainberg, Z Gu, Q Gao, E Arts, R Geleziunas, S Bour, R Beaulieu, C Tsoukas, J Singer, J Montaner Journal of acquired immune deficiency syndromes 1993 pols set
A single-stranded DNA binding protein from Drosophila melanogaster: characterization of the heterotrimeric protein and its interaction with single-stranded DNA. P G Mitsis, SC Kowalczykowski, I. Robert Lehman Biochemistry 1993 new
Fidelity of phi 29 DNA polymerase. Comparison between protein-primed initiation and DNA polymerization. J A Esteban, Margarita Salas, Luis Blanco The Journal of biological chemistry 1993 pols set
dUTPase from herpes simplex virus type 1; purification from infected green monkey kidney (Vero) cells and from an overproducing Escherichia coli strain. O Björnberg, AC Bergman, AM Rosengren, R Persson, I. Robert Lehman, PO Nyman Protein expression and purification 1993 new
Cloning of the DNA polymerase gene of Bacillus caldotenax and characterization of the gene product. Takashi Uemori, Yoshizumi Ishino, K Fujita, Kiyozo Asada, Ikunoshin Kato J Biochem 1993 new
[Isolation of protein phosphokinase from a complex form of DNA polymerase alpha from rat liver]. Igor V Shevelev, S N Naryzhnyĭ, V M Krutiakov Mol Biol (Mosk) 1993 new
Site directed mutagenesis of DNA polymerase I (Klenow) from Escherichia coli. The significance of Arg682 in catalysis. V N Pandey, Neerja Kaushik, R P Sanzgiri, M S Patil, Mukund J Modak, S Barik Eur J Biochem 1993 pols set
Adenovirus DNA polymerase is phosphorylated by a stably associated histone H1 kinase. M Ramachandra, R Padmanabhan The Journal of biological chemistry 1993 new
Mutational studies of human DNA polymerase alpha. Identification of residues critical for deoxynucleotide binding and misinsertion fidelity of DNA synthesis. Q Dong, William C Copeland, Teresa S-F Wang The Journal of biological chemistry 1993 pols set
Interaction of DNA polymerase delta, proliferating cell nuclear antigen, and synthetic oligonucleotide template-primers. Analysis by polyacrylamide gel electrophoresis-band mobility shift assay. L Ng, Maeve McConnell, Cheng-Keat Tan, Kathleen M Downey, Paul A Fisher The Journal of biological chemistry 1993 new
Resistance of clinical isolates of human immunodeficiency virus to antiretroviral agents. Douglas D Richman Antimicrobial agents and chemotherapy 1993 pols set
Processivity of mitochondrial DNA polymerase from Drosophila embryos. Effects of reaction conditions and enzyme purity. A J Williams, C M Wernette, Laurie S Kaguni The Journal of biological chemistry 1993 new
DNA polymerase alpha stimulates the ATP-dependent binding of simian virus tumor T antigen to the SV40 origin of replication. Y Murakami, Jerard Hurwitz The Journal of biological chemistry 1993 new
Rapid assembly of the bacteriophage T4 core replication complex on a linear primer/template construct. B F Kaboord, Stephen J Benkovic Proceedings of the National Academy of Sciences of the United States of America 1993 topics set
Detection and characterization of mammalian DNA polymerase beta mutants by functional complementation in Escherichia coli. Joann B Sweasy, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1993 pols set
[Effects of Ganoderma polysaccharides on the activity of DNA polymerase alpha of splenocytes and immune function in aged mice]. L S Lei, Z B Lin Yao Xue Xue Bao 1993 new
In vitro replication of bacteriophage PRD1 DNA. Characterization of the protein-primed initiation site. J Caldentey, Luis Blanco, D H Bamford, Margarita Salas Nucleic acids research 1993 new
DNA polymerase I and the bypassing of RecA dependence of constitutive stable DNA replication in Escherichia coli rnhA mutants. Y Cao, R R Rowland, T Kogoma J Bacteriol 1993 new
DNA polymerase delta from embryos of Drosophila melanogaster. C S Chiang, P G Mitsis, I. Robert Lehman Proceedings of the National Academy of Sciences of the United States of America 1993 new
DNA polymerase-alpha is essential for mating-type switching in fission yeast. J Singh, A J Klar Nature 1993 new
The 3'-5' exonuclease of human DNA polymerase delta (pol delta) is regulated by pol delta accessory factors and deoxyribonucleoside triphosphates. S H Lee Nucleic acids research 1993 pols set
An error-correcting proofreading exonuclease-polymerase that copurifies with DNA-polymerase-alpha-primase. G Bialek, Frank Grosse The Journal of biological chemistry 1993 pols set
Molecular cloning of the cDNAs for the four subunits of mouse DNA polymerase alpha-primase complex and their gene expression during cell proliferation and the cell cycle. Hiroshi Miyazawa, M Izumi, S Tada, R Takada, Mitsuko Masutani, M Ui, Fumio Hanaoka The Journal of biological chemistry 1993 new
Dideoxy sequencing reactions using Klenow fragment DNA polymerase 1. A T Bankier Methods in molecular biology (Clifton, N.J.) 1993 pols set
Lagging strand DNA synthesis by calf thymus DNA polymerases alpha, beta, delta and epsilon in the presence of auxiliary proteins. Vladimir N Podust, Ulrich Hübscher Nucleic acids research 1993 topics set
Codons 12 and 13 of H-ras protooncogene interrupt the progression of DNA synthesis catalyzed by DNA polymerase alpha. Jean-Sébastien Hoffmann, M Fry, J Ji, K J Williams, Lawrence A Loeb Cancer research 1993 new
HIV-1-specific reverse transcriptase inhibitors show differential activity against HIV-1 mutant strains containing different amino acid substitutions in the reverse transcriptase. Jan Balzarini, Anna Karlsson, María-Jesús Pérez-Pérez, L Vrang, J Walbers, Haijiang Zhang, Bo Oberg, A-M Vandamme, María-José Camarasa, Erik De Clercq Virology 1993 pols set
Conserved sites in the 5'-3' exonuclease domain of Escherichia coli DNA polymerase. P D Gutman, K W Minton Nucleic acids research 1993 pols set
Treatment of human immunodeficiency virus type 1 (HIV-1)-infected cells with combinations of HIV-1-specific inhibitors results in a different resistance pattern than does treatment with single-drug therapy. Jan Balzarini, Anna Karlsson, María-Jesús Pérez-Pérez, María-José Camarasa, W G Tarpley, Erik De Clercq Journal of virology 1993 pols set
Human DNA helicase V, a novel DNA unwinding enzyme from HeLa cells. N Tuteja, K Rahman, R Tuteja, A Falaschi Nucleic acids research 1993 topics set
Re-engineering the polymerase domain of Klenow fragment and evaluation of overproduction and purification strategies. V Derbyshire, Mekbib Astatke, Catherine M Joyce Nucleic acids research 1993 pols set
Isolation of a new species of Physarum lysophosphatidic acid, PHYLPA, and its effect on DNA polymerase activity. Y Takahashi, Y Shimada, M Shioda, Shonen Yoshida, H Murofushi, K Murakami-Murofushi Cell Struct Funct 1993 new
Human immunodeficiency virus type 1-specific [2',5'-bis-O-(tert- butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5"-(4"-amino-1",2"- oxathiole-2",2"-dioxide)-purine analogues show a resistance spectrum that is different from that of the human immunodeficiency virus type 1-specific non-nucleoside analogues. Jan Balzarini, Sonsoles Velazquez, A San-Felix, Anna Karlsson, M J Perez-Perez, María-José Camarasa, Erik De Clercq Molecular pharmacology 1993 pols set
DNA unwinding by replication protein A is a property of the 70 kDa subunit and is facilitated by phosphorylation of the 32 kDa subunit. A Georgaki, Ulrich Hübscher Nucleic acids research 1993 new
Human immunodeficiency virus type 1 (HIV-1) strains selected for resistance against the HIV-1-specific [2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro- 5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)]-beta-D-pentofurano syl (TSAO) nucleoside analogues retain sensitivity to HIV-1-specific nonnucleoside inhibitors. Jan Balzarini, Anna Karlsson, A-M Vandamme, María-Jesús Pérez-Pérez, Haijiang Zhang, L Vrang, Bo Oberg, K Bäckbro, Torsten Unge, Ana San-Félix Proceedings of the National Academy of Sciences of the United States of America 1993 pols set
Mosquito DNA polymerase epsilon. S K Lee, M S Fuchs FEBS letters 1993 pols set
A mutation in reverse transcriptase of bis(heteroaryl)piperazine-resistant human immunodeficiency virus type 1 that confers increased sensitivity to other nonnucleoside inhibitors. T J Dueweke, T Pushkarskaya, S M Poppe, S M Swaney, J Q Zhao, I S Chen, M Stevenson, W G Tarpley Proceedings of the National Academy of Sciences of the United States of America 1993 pols set
Selective action of 4'-azidothymidine triphosphate on reverse transcriptase of human immunodeficiency virus type 1 and human DNA polymerases alpha and beta. M S Chen, R T Suttmann, E Papp, P D Cannon, M J McRoberts, C Bach, William C Copeland, Teresa S-F Wang Biochemistry 1993 pols set
Initiation of simian virus 40 DNA replication requires the interaction of a specific domain of human DNA polymerase alpha with large T antigen. I Dornreiter, William C Copeland, Teresa S-F Wang Molecular and cellular biology 1993 pols set
Organization and nucleotide sequence of the DNA polymerase gene from the archaeon Pyrococcus furiosus. Takashi Uemori, Yoshizumi Ishino, H Toh, Kiyozo Asada, Ikunoshin Kato Nucleic acids research 1993 new
A point mutation in the human cytomegalovirus DNA polymerase gene confers resistance to ganciclovir and phosphonylmethoxyalkyl derivatives. V Sullivan, K K Biron, C Talarico, S C Stanat, M Davis, L M Pozzi, Donald M Coen Antimicrob Agents Chemother 1993 pols set
The subunits of activator 1 (replication factor C) carry out multiple functions essential for proliferating-cell nuclear antigen-dependent DNA synthesis. Z Q Pan, M Chen, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1993 new
Functional analysis of the herpes simplex virus UL42 protein. P Digard, C S Chow, L Pirrit, Donald M Coen Journal of virology 1993 new
Purification and characterization of a yeast DNA polymerase alpha complex with associated primase, 5'-->3' exonuclease, and DNA-dependent ATPase activities. Esther E Biswas, P H Chen, W Gray, Y H Li, S Ray, Subhasis B Biswas Biochemistry 1993 new
Detection and characterization of DNA polymerase activity in Toxoplasma gondii. A Makioka, B Stavros, J T Ellis, A M Johnson Parasitology 1993 new
DNA polymerase III is required for DNA repair in Saccharomyces cerevisiae. W Suszek, H Baranowska, J Zuk, W J Jachymczyk Curr Genet 1993 new
Identification, isolation, and characterization of the structural gene encoding the delta' subunit of Escherichia coli DNA polymerase III holoenzyme. J R Carter, M A Franden, R Aebersold, Charles S McHenry Journal of bacteriology 1993 pols set
Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase. M Tisdale, S D Kemp, N R Parry, Brendan A Larder Proceedings of the National Academy of Sciences of the United States of America 1993 topics set
Activity of a novel quinoxaline derivative against human immunodeficiency virus type 1 reverse transcriptase and viral replication. Jörg-Peter Kleim, R Bender, U M Billhardt, C Meichsner, G Riess, M Rösner, I Winkler, A Paessens Antimicrobial agents and chemotherapy 1993 pols set
Fission yeast with DNA polymerase delta temperature-sensitive alleles exhibits cell division cycle phenotype. S Francesconi, H Park, Teresa S-F Wang Nucleic acids research 1993 new
Viral resistance to the thiazolo-iso-indolinones, a new class of nonnucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase. G Maass, U Immendoerfer, B Koenig, U Leser, B Mueller, R Goody, E Pfaff Antimicrobial agents and chemotherapy 1993 pols set
Human immunodeficiency virus type 1 drug-resistance patterns with different 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives. Jan Balzarini, Anna Karlsson, Erik De Clercq Molecular pharmacology 1993 pols set
Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides. Raymond F Schinazi, R M Lloyd, M H Nguyen, D L Cannon, A McMillan, N Ilksoy, Chung K Chu, Dennis C Liotta, Holly Z Bazmi, John W Mellors Antimicrob Agents Chemother 1993 pols set
Assembly of a functional replication complex without ATP hydrolysis: a direct interaction of bacteriophage T4 gp45 with T4 DNA polymerase. M K Reddy, S E Weitzel, Peter H von Hippel Proceedings of the National Academy of Sciences of the United States of America 1993 complete
A single conservative amino acid substitution in the reverse transcriptase of human immunodeficiency virus-1 confers resistance to (+)-(5S)-4,5,6,7-tetrahydro-5-methyl-6-(3-methyl-2-butenyl)imidazo[4,5, 1- jk][1,4]benzodiazepin-2(1H)-thione (TIBO R82150). John W Mellors, G J Im, Enzo Tramontano, S R Winkler, D J Medina, Ginger E Dutschman, Holly Z Bazmi, G Piras, C J Gonzalez, Yung-Chi Cheng Molecular pharmacology 1993 pols set
Polymerase chain reaction-based mRNA quantification using an internal standard: analysis of oncogene expression. R H Scheuermann, S R Bauer Methods in enzymology 1993 new
Purification and characterization of Thermus caldophilus GK24 DNA polymerase. J H Park, Joong Su Kim, Suk-Tae Kwon, D S Lee Eur J Biochem 1993 new
Comprehensive mutant enzyme and viral variant assessment of human immunodeficiency virus type 1 reverse transcriptase resistance to nonnucleoside inhibitors. V W Byrnes, V V Sardana, W A Schleif, J H Condra, J A Waterbury, J A Wolfgang, W J Long, C L Schneider, A J Schlabach, B S Wolanski Antimicrobial agents and chemotherapy 1993 pols set
DNA polymerase II, the epsilon polymerase of Saccharomyces cerevisiae. A Morrison, Akio Sugino Prog Nucleic Acid Res Mol Biol 1993 pols set
Comparison of interactions of 5'-derivatives of deoxyoctathymidylate with human DNA polymerize alpha and HIV reverse transcriptase. Svetlana N Khodyreva, Vladimir N Podust, D S Sergeev, E M Ivanova, E I Frolova, A A Koshkin, T S Godovikova, V F Zarytova, Miria Ricchetti, Olga I Lavrik Molecular biology reports 1993 pols set
Nuclear and kinetoplast DNA synthesis in Trypanosoma cruzi, autoradiographical study with DNA polymerase inhibitors. C Rojas, C Gutierrez, Simon Litvak, A Solari Int J Parasitol 1993 new
Purification and characterization of a gamma-like DNA polymerase from Chenopodium album L. K Meissner, S Heinhorst, G C Cannon, T Börner Nucleic acids research 1993 partial results
Proof-reading 3'-->5' exonucleases isolated from rat liver nuclei. N V Belyakova, N E Kleiner, T P Kravetskaya, O K Legina, S N Naryzhny, Fred W Perrino, I V Shevelev, V M Krutyakov European journal of biochemistry / FEBS 1993 new
DNA polymerase III accessory proteins. II. Characterization of delta and delta'. R Onrust, Mike E O'Donnell The Journal of biological chemistry 1993 new
In vivo phosphorylation, mitotic behavior, and nuclear binding of the catalytic subunit of DNA polymerase alpha in fission yeast. D Bouvier, A M de Recondo, Giuseppe Baldacci Exp Cell Res 1993 new
Sliding clamps of DNA polymerases. John Kuriyan, Mike E O'Donnell Journal of molecular biology 1993 new
Enhanced expression of alpha-type DNA polymerase genes reduces AZT cytotoxicity in hamster tr5 cells. P K Liu Somat Cell Mol Genet 1993 new
Requirement for the polymerization and 5'-->3' exonuclease activities of DNA polymerase I in initiation of DNA replication at oriK sites in the absence of RecA in Escherichia coli rnhA mutants. Y Cao, T Kogoma J Bacteriol 1993 new
Mammalian proliferating cell nuclear antigen stimulates the processivity of two wheat embryo DNA polymerases. Patricia Laquel, Simon Litvak, Michel Castroviejo Plant Physiol 1993 partial results
The DNA polymerase-encoding gene of African swine fever virus: sequence and transcriptional analysis. Javier M Rodríguez, R J Yáñez, J F Rodríguez, E Viñuela, María L Salas Gene 1993 pols set
Human immunodeficiency virus reverse transcriptase. Expression in Escherichia coli, purification, and characterization of a functionally and structurally asymmetric dimeric polymerase. R L Thimmig, Charles S McHenry The Journal of biological chemistry 1993 pols set
Structure of DNA polymerase I Klenow fragment bound to duplex DNA. Lorena S Beese, V Derbyshire, Thomas A Steitz Science 1993 complete
Inhibition of B cell expression of DNA polymerase alpha by CD4+ suppressor T cells. S Hirohata Cell Immunol 1993 new
Purification and characterization of the DNA-binding activity of the Epstein-Barr virus DNA polymerase accessory protein BMRF1 gene products, as expressed in insect cells by using the baculovirus system. Tatsuya Tsurumi J Virol 1993 pols set
Effects of the anticancer drug cis-diamminedichloroplatinum(II) on the activities of calf thymus DNA polymerase epsilon. L Huang, J J Turchi, A F Wahl, Robert A Bambara Biochemistry 1993 new
Expression of polypeptides of human immunodeficiency virus-1 reverse transcriptase in Escherichia coli. S P Becerra, A Kumar, Samuel H Wilson Protein expression and purification 1993 pols set
Error-prone polymerization by HIV-1 reverse transcriptase. Contribution of template-primer misalignment, miscoding, and termination probability to mutational hot spots. Katarzyna Bebenek, J Abbotts, Samuel H Wilson, Thomas A Kunkel The Journal of biological chemistry 1993 pols set
Crystal structure of bacteriophage T7 RNA polymerase at 3.3 A resolution. R Sousa, Y J Chung, J P Rose, B C Wang Nature 1993 new
Yeast open reading frame YCR14C encodes a DNA beta-polymerase-like enzyme. Rajendra Prasad, S G Widen, R K Singhal, J Watkins, Louise Prakash, Samuel H Wilson Nucleic acids research 1993 new
HIV-1 reverse transcriptase: inhibition by 2',5'-oligoadenylates. Robert W Sobol, W L Fisher, N L Reichenbach, A Kumar, William A Beard, Samuel H Wilson, R Charubala, W Pfleiderer, R J Suhadolnik Biochemistry 1993 pols set
Kinetic analysis of template.primer interactions with recombinant forms of HIV-1 reverse transcriptase. William A Beard, Samuel H Wilson Biochemistry 1993 pols set
Mapping of nucleic acid binding in proteolytic domains of HIV-1 reverse transcriptase. A Kumar, H R Kim, Robert W Sobol, S P Becerra, B J Lee, D L Hatfield, R J Suhadolnik, Samuel H Wilson Biochemistry 1993 pols set
Crystal structures of the Klenow fragment of DNA polymerase I complexed with deoxynucleoside triphosphate and pyrophosphate. Lorena S Beese, J M Friedman, Thomas A Steitz Biochemistry 1993 complete
Mechanism of HIV-1 reverse transcriptase. Termination of processive synthesis on a natural DNA template is influenced by the sequence of the template-primer stem. J Abbotts, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson The Journal of biological chemistry 1993 pols set
Structure/function studies of HIV-1(1) reverse transcriptase: dimerization-defective mutant L289K. R Goel, William A Beard, A Kumar, J R Casas-Finet, M P Strub, S J Stahl, M S Lewis, Katarzyna Bebenek, S P Becerra, Thomas A Kunkel Biochemistry 1993 pols set
Kinetics of deoxyribonucleotide insertion and extension at abasic template lesions in different sequence contexts using HIV-1 reverse transcriptase. H Cai, Linda B Bloom, R Eritja, Myron F Goodman The Journal of biological chemistry 1993 pols set
The herpes simplex virus type 1 DNA polymerase accessory protein, UL42, contains a functional protease-resistant domain. Robert K Hamatake, M Bifano, Daniel J Tenney, W W Hurlburt, M G Cordingley The Journal of general virology 1993 new
DNA repair synthesis during base excision repair in vitro is catalyzed by DNA polymerase epsilon and is influenced by DNA polymerases alpha and delta in Saccharomyces cerevisiae. Zhengqiang Wang, Xiaoming Wu, Errol C Friedberg Molecular and cellular biology 1993 pols set
RNA priming coupled with DNA synthesis on natural template by calf thymus DNA polymerase alpha-primase. Motoshi Suzuki, E Savoysky, Shunji Izuta, M Tatebe, T Okajima, Shonen Yoshida Biochemistry 1993 new
Inverted DNA repeats: a source of eukaryotic genomic instability. Dmitry A Gordenin, K S Lobachev, N P Degtyareva, A L Malkova, E Perkins, Michael A Resnick Molecular and cellular biology 1993 topics set
Bacteriophage T4 DNA polymerase mutations that confer sensitivity to the PPi analog phosphonoacetic acid. Linda J Reha-Krantz, R L Nonay, S Stocki J Virol 1993 complete
Evidence for a novel regulatory pathway for herpes simplex virus gene expression in trigeminal ganglion neurons. M Kosz-Vnenchak, J Jacobson, Donald M Coen, David M Knipe Journal of virology 1993 new
Preparation of DNA polymerase from Bacillus caldotenax. J A Burrows, C R Goward J Chromatogr 1993 new
Absence of high levels of DNA polymerase alpha activity in the nuclear matrix prepared from mouse erythroleukemia cells. A M Martelli, L M Neri, A M Billi, R Bareggi, L Cocco Cell Biol Int 1993 new
[Features of interaction of Escherichia coli DNA polymerase I and its Klenow fragment with dTTP gamma-p-azidoanilide]. N V Kudriashova, M Iu Shamanina, T S Godovikova, E A Anan'ko, F F Akhmadieva, A G Romashchenko Biokhimiia 1993 pols set
DNA polymerase-catalyzed addition of nontemplated extra nucleotides to the 3' end of a DNA fragment. G Hu DNA Cell Biol 1993 new
Cyclobutane thymine dimers in a ras proto-oncogene hot spot activate the gene by point mutation. Hiroyuki Kamiya, N Murata, T Murata, Shigenori Iwai, Akio Matsukage, Chikahide Masutani, Fumio Hanaoka, E Ohtsuka Nucleic acids research 1993 new
DNA polymerase III accessory proteins. I. holA and holB encoding delta and delta'. Z Dong, R Onrust, Maija Skangalis, Mike E O'Donnell The Journal of biological chemistry 1993 new
A mammalian protein complex that repairs double-strand breaks and deletions by recombination. R Jessberger, V Podust, Ulrich Hübscher, P Berg The Journal of biological chemistry 1993 new
Purification and characterization of the Saccharomyces cerevisiae DNA polymerase delta overproduced in Escherichia coli. W C Brown, J A Duncan, Judith L Campbell The Journal of biological chemistry 1993 pols set
Biochemical basis of DNA replication fidelity. Myron F Goodman, S Creighton, Linda B Bloom, John Petruska Crit Rev Biochem Mol Biol 1993 complete
[Study of the interaction of DNA primase from calf thymus and human placenta with oligonucleotides matrices of various length and structure]. Rashid O Anarbaev, Vladimir N Podust, O D Zakharova, Olga I Lavrik Biokhimii͡a (Moscow, Russia) 1993 new
Phi 29 DNA polymerase active site. The conserved amino acid motif "Kx3NSxYG" is involved in template-primer binding and dNTP selection. M A Blasco, José María Lázaro, Luis Blanco, Margarita Salas The Journal of biological chemistry 1993 pols set
Functional interactions between SV40 T antigen and other replication proteins at the replication fork. Y Murakami, Jerard Hurwitz The Journal of biological chemistry 1993 new
'Footprinting' proteins on DNA with peroxonitrous acid. P A King, E Jamison, D Strahs, V E Anderson, M Brenowitz Nucleic acids research 1993 new
Enzymatic characterization of the individual mammalian primase subunits reveals a biphasic mechanism for initiation of DNA replication. William C Copeland, Teresa S-F Wang The Journal of biological chemistry 1993 new
Patch length of localized repair events: role of DNA polymerase I in mutY-dependent mismatch repair. J P Radicella, E A Clark, S Chen, M S Fox J Bacteriol 1993 new
Phi 29 DNA polymerase active site. Residue ASP249 of conserved amino acid motif "Dx2SLYP" is critical for synthetic activities. M A Blasco, José María Lázaro, Luis Blanco, Margarita Salas The Journal of biological chemistry 1993 new
Fidelity of DNA synthesis catalyzed by human DNA polymerase alpha and HIV-1 reverse transcriptase: effect of reaction pH. Kristin A Eckert, Thomas A Kunkel Nucleic acids research 1993 partial results
Mechanism of resistance of human immunodeficiency virus type 1 to 2',3'-dideoxyinosine. J L Martin, J E Wilson, R L Haynes, Phillip A Furman Proceedings of the National Academy of Sciences of the United States of America 1993 topics set
Activation of the mouse DNA polymerase beta gene promoter by adenovirus type 12 E1A proteins. Masamitsu Yamaguchi, Y Hayashi, Fumiko Hirose, K Shiroki, Akio Matsukage Nucleic acids research 1992 topics set
DNA polymerase alpha in the fission yeast Schizosaccharomyces pombe: identification and tracing of the catalytic subunit during the cell cycle. D Bouvier, G Pignede, V Damagnez, J Tillit, A M de Recondo, Giuseppe Baldacci Exp Cell Res 1992 new
Enzymatic syntheses of DNA-silicas using DNA polymerase. L R Solomon, L R Massom, H W Jarrett Anal Biochem 1992 new
Inhibition of eukaryotic DNA polymerase alpha with a novel lysophosphatidic acid (PHYLPA) isolated from myxoamoebae of Physarum polycephalum. K Murakami-Murofushi, M Shioda, K Kaji, Shonen Yoshida, H Murofushi The Journal of biological chemistry 1992 new
2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase. Jan Balzarini, María-Jesús Pérez-Pérez, Ana San-Félix, Dominique Schols, CF Perno, A-M Vandamme, María-José Camarasa, Erik De Clercq Proceedings of the National Academy of Sciences of the United States of America 1992 pols set
Interaction of Drosophila DNA polymerase alpha holoenzyme with synthetic template-primers containing mismatched primer bases or propanodeoxyguanosine adducts at various positions in template and primer regions. S J Weiss, Paul A Fisher The Journal of biological chemistry 1992 new
Selective immunoneutralization of the multiple activities of Escherichia coli DNA polymerase I supports the model for separate active sites and indicates a complex 5' to 3' exonuclease. T Ruscitti, D A Polayes, A E Karu, Stuart Linn The Journal of biological chemistry 1992 pols set
Isolation and partial characterization of a high-molecular-weight DNA polymerase from Leishmania mexicana. L L Nolan, J H Rivera, N N Khan Biochimica et biophysica acta 1992 new
3'-Azido-3'-deoxythymidine resistance suppressed by a mutation conferring human immunodeficiency virus type 1 resistance to nonnucleoside reverse transcriptase inhibitors. Brendan A Larder Antimicrob Agents Chemother 1992 topics set
Point mutations which drastically affect the polymerization activity of encephalomyocarditis virus RNA-dependent RNA polymerase correspond to the active site of Escherichia coli DNA polymerase I. S Sankar, A G Porter The Journal of biological chemistry 1992 pols set
The c-myb proto-oncogene product binds to but does not activate the promoter of the DNA polymerase alpha gene. T Sudo, Hiroshi Miyazawa, Fumio Hanaoka, S Ishii Oncogene 1992 new
Reactions at the polymerase active site that contribute to the fidelity of Escherichia coli DNA polymerase I (Klenow fragment). Catherine M Joyce, Xiaojun Chen Sun, Nigel D F Grindley The Journal of biological chemistry 1992 pols set
Cassette mutagenesis of the reverse transcriptase of human immunodeficiency virus type 1. Paul L Boyer, Andrea L Ferris, Stephen H Hughes Journal of virology 1992 new
Selective inhibition of HIV replication by adriamycin in macrophages but not in lymphocytes. Alberto Bergamini, CF Perno, Jan Balzarini, M Capozzi, Luciana Marinelli, G Milanese, C D Pesce, R Calió, G Rocchi AIDS research and human retroviruses 1992 pols set
Three-dimensional structure of the beta subunit of E. coli DNA polymerase III holoenzyme: a sliding DNA clamp. Xiang-Peng Kong, R Onrust, Mike E O'Donnell, John Kuriyan Cell 1992 topics set
RNA analysis from newborn screening dried blood specimens. Y H Zhang, E R McCabe Human genetics 1992 new
In vitro selection of variants of human immunodeficiency virus type 1 resistant to 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine. Q Gao, Z X Gu, Michael A. Parniak, X G Li, Mark A. Wainberg Journal of virology 1992 pols set
Fidelity of HIV-1 reverse transcriptase copying RNA in vitro. J P Ji, Lawrence A Loeb Biochemistry 1992 new
Levels of epsilon, an essential replication subunit of Escherichia coli DNA polymerase III, are controlled by heat shock proteins. Patricia L Foster, M G Marinus J Bacteriol 1992 pols set
DNA replication defect in Salmonella typhimurium mutants lacking the editing (epsilon) subunit of DNA polymerase III. M R Lifsics, E D Lancy, R Maurer J Bacteriol 1992 new
Inhibitory effects of triphosphate derivatives of oxetanocin G and related compounds on eukaryotic and viral DNA polymerases and human immunodeficiency virus reverse transcriptase. Shunji Izuta, N Shimada, Masatoshi Kitagawa, Motoshi Suzuki, K Kojima, Shonen Yoshida Journal of biochemistry 1992 pols set
Human immunodeficiency virus type 1 reverse transcriptase: spatial and temporal relationship between the polymerase and RNase H activities. V Gopalakrishnan, J A Peliska, Stephen J Benkovic Proceedings of the National Academy of Sciences of the United States of America 1992 partial results
Photoaffinity labeling of DNA polymerase alpha DNA primase complex based on the catalytic competence of a dNTP reactive analog. S V Doronin, M I Dobrikov, Olga I Lavrik FEBS letters 1992 topics set
The affinity of the Klenow fragment of E. coli DNA-polymerase 1 to primers containing bases noncomplementary to the template and hairpin-like elements. M V Ljach, T I Kolocheva, V V Gorn, A S Levina, G A Nevinsky FEBS letters 1992 pols set
A complex between replication factor A (SSB) and DNA helicase stimulates DNA synthesis of DNA polymerase alpha on double-stranded DNA. Sufang Zhang, Frank Grosse FEBS letters 1992 new
Structure of HIV-1 reverse transcriptase/DNA complex at 7 A resolution showing active site locations. Edward Arnold, A Jacobo-Molina, R G Nanni, R L Williams, Xiaoqing Lu, Jianping Ding, Art D Clark, A Zhang, Andrea L Ferris, Patrick K Clark Nature 1992 pols set
Functional analysis of HIV-1 reverse transcriptase amino acids involved in resistance to multiple nonnucleoside inhibitors. V V Sardana, E A Emini, L Gotlib, D J Graham, D W Lineberger, W J Long, A J Schlabach, J A Wolfgang, J H Condra The Journal of biological chemistry 1992 topics set
Lobenzarit disodium (CCA) inhibits the proliferation of human endothelial cells and the activity of DNA polymerase alpha. F Takeuchi, E Kosuge, Y Hashimoto, K Matsuta, Fumio Hanaoka, K Tanimoto, K Ito Agents Actions 1992 new
Polymerase chain reaction amplification of single-stranded DNA containing a base analog, 2-chloradenine. P Hentosh, J C McCastlain, P Grippo, B Y Bugg Anal Biochem 1992 topics set
Production of multiple forms during purification of Streptomyces aureofaciens DNA polymerase: a study using nondenaturing polyacrylamide gradient gel electrophoresis. J Kosovský, Z Subr, K Popovnáková, J Zelinka Biochimica et biophysica acta 1992 new
Post-incision steps of nucleotide excision repair in Escherichia coli. Disassembly of the UvrBC-DNA complex by helicase II and DNA polymerase I. D K Orren, C P Selby, J E Hearst, A Sancar The Journal of biological chemistry 1992 new
Human immunodeficiency virus type 1 reverse transcriptase. Affinity labeling of the primer binding site. R L Mitina, S V Doronin, M I Dobrikov, D R Tabatadze, A S Levina, Olga I Lavrik FEBS letters 1992 pols set
Effects of Tokishakuyakusan, Keishibukuryogan and Unkeito on DNA polymerase alpha activity in PMS-treated immature rat uterus incubated in vitro. S Usuki Am J Chin Med 1992 new
Molecular cloning, sequencing, and overexpression of the structural gene encoding the delta subunit of Escherichia coli DNA polymerase III holoenzyme. J R Carter, M A Franden, R Aebersold, Charles S McHenry J Bacteriol 1992 pols set
A 5' to 3' exonuclease functionally interacts with calf DNA polymerase epsilon. Gregg Siegal, J J Turchi, T W Myers, Robert A Bambara Proceedings of the National Academy of Sciences of the United States of America 1992 new
Two regions in human DNA polymerase beta mRNA suppress translation in Escherichia coli. T Date, K Tanihara, S Yamamoto, N Nomura, Akio Matsukage Nucleic acids research 1992 pols set
Extension of base mispairs by Taq DNA polymerase: implications for single nucleotide discrimination in PCR. M M Huang, Norman Arnheim, Myron F Goodman Nucleic acids research 1992 pols set
Calf thymus RF-C as an essential component for DNA polymerase delta and epsilon holoenzymes function. Vladimir N Podust, A Georgaki, B Strack, Ulrich Hübscher Nucleic acids research 1992 new
Isolation of DNA polymerase alpha from germinated wheat embryos. T S Balmukhanov, A M Erekenov, N A Ajtkhozhina Mol Biol Rep 1992 new
The bacteriophage phi 29 DNA polymerase, a proofreading enzyme. C Garmendia, Antonio Bernad, J A Esteban, Luis Blanco, Margarita Salas The Journal of biological chemistry 1992 partial results
[Analogs of nucleotides, modified by a sugar residue and pyrimidine base, in a DNA synthesis reaction, catalyzed by Thermus aquaticus DNA polymerase]. L P Savochkina, L B Dĭachenko, M A Lukin, L A Aleksandrova Mol Biol (Mosk) 1992 pols set
The effect of the UL42 protein on the DNA polymerase activity of the catalytic subunit of the DNA polymerase encoded by herpes simplex virus type 1. G J Hart, R E Boehme FEBS letters 1992 new
Nucleotide sequence of the POL3 gene encoding DNA polymerase III (delta) of Saccharomyces cerevisiae. A Morrison, Akio Sugino Nucleic acids research 1992 pols set
Structural and functional studies on phi 29 DNA polymerase. M A Blasco, J A Esteban, Juan Méndez, Luis Blanco, Margarita Salas Chromosoma 1992 pols set
Human immunodeficiency virus type 1 pol gene mutations which cause decreased susceptibility to 2',3'-dideoxycytidine. J E Fitzgibbon, R M Howell, C A Haberzettl, S J Sperber, D J Gocke, D T Dubin Antimicrobial agents and chemotherapy 1992 pols set
The 5' to 3' exonuclease activity of DNA polymerase I is essential for Streptococcus pneumoniae. A Díaz, S A Lacks, P López Molecular microbiology 1992 partial results
Kinetics of inhibition of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase by the novel HIV-1-specific nucleoside analogue [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5 "- (4"-amino-1",2"-oxathiole-2",2"-dioxide)thymine (TSAO-T). Jan Balzarini, María-Jesús Pérez-Pérez, Ana San-Félix, María-José Camarasa, I C Bathurst, P J Barr, Erik De Clercq The Journal of biological chemistry 1992 pols set
Evidence that POB1, a Saccharomyces cerevisiae protein that binds to DNA polymerase alpha, acts in DNA metabolism in vivo. J Miles, T Formosa Molecular and cellular biology 1992 new
A point mutation within a distinct conserved region of the herpes simplex virus DNA polymerase gene confers drug resistance. Charles B C Hwang, K L Ruffner, Donald M Coen Journal of virology 1992 new
Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine. P Kellam, Charles A B Boucher, Brendan A Larder Proceedings of the National Academy of Sciences of the United States of America 1992 topics set
[Preparation of 5-(125)iodine-2'-deoxyuridine triphosphate and incorporation of the labeled nucleotide into DNA by polymerase chain reaction] P Sherberg, S Dzekhtser Bioorg Khim 1992 topics set
A rapid polymerase-chain-reaction-directed sequencing strategy using a thermostable DNA polymerase from Thermus flavus. V B Rao, N B Saunders Gene 1992 new
Real-time monitoring of DNA polymerase reactions by a micro ISFET pH sensor. T Sakurai, Y Husimi Anal Chem 1992 new
Prereplicative complexes of components of DNA polymerase III holoenzyme of Escherichia coli. L G Fradkin, Arthur Kornberg The Journal of biological chemistry 1992 pols set
[Production of CA125 in cell lines derived from human ovarian carcinoma: in relation to the cell cycle]. Motoshi Suzuki, J Ma, N Usui, Y Furugen, M Takada Nihon Sanka Fujinka Gakkai zasshi 1992 new
p53 mutations in non-small cell lung cancer in Japan: association between mutations and smoking. H Suzuki, T Takahashi, T Kuroishi, M Suyama, Y Ariyoshi, T Takahashi, R Ueda Cancer research 1992 new
The DNA polymerase-encoding gene of Bacillus subtilis bacteriophage SPO1. V Scarlato, S Gargano Gene 1992 topics set
Eukaryotic DNA primase appears to act as oligomer in DNA-polymerase-alpha--primase complex. Vladimir N Podust, O V Vladimirova, E N Manakova, Olga I Lavrik European journal of biochemistry / FEBS 1992 new
Overproduction of DnaE protein (alpha subunit of DNA polymerase III) restores viability in a conditionally inviable Escherichia coli strain deficient in DNA polymerase I. E M Witkin, V Roegner-Maniscalco J Bacteriol 1992 new
Overproduction of the beta subunit of DNA polymerase III holoenzyme reduces UV mutagenesis in Escherichia coli. Y Tadmor, R Ascarelli-Goell, R Skaliter, Zvi Livneh J Bacteriol 1992 new
The reverse DNA sequencing using Bst DNA polymerase. Y Lu, S Ye, G Hong Chin J Biotechnol 1992 pols set
Calmodulin regulates DNA polymerase alpha activity during proliferative activation of NRK cells. A López-Girona, J Colomer, M J Pujol, Oriol Bachs, Neus Agell Biochem Biophys Res Commun 1992 new
DNA-independent deoxynucleotidylation of the phi 29 terminal protein by the phi 29 DNA polymerase. Luis Blanco, Antonio Bernad, J A Esteban, Margarita Salas The Journal of biological chemistry 1992 pols set
Mutational analysis of the fingers domain of human immunodeficiency virus type 1 reverse transcriptase. Paul L Boyer, Andrea L Ferris, Stephen H Hughes Journal of virology 1992 pols set
Minimizing deletion mutagenesis artifact during Taq DNA polymerase PCR by E. coli SSB. Q Chou Nucleic acids research 1992 pols set
Heterogeneity of a herpes simplex virus clinical isolate exhibiting resistance to acyclovir and foscarnet. E Pelosi, K A Hicks, S L Sacks, Donald M Coen Advances in experimental medicine and biology 1992 new
DNA Replication Book: DNA Replication 1992 complete
DNA polymerase-delta from the silk glands of Bombyx mori. S Niranjanakumari, K P Gopinathan The Journal of biological chemistry 1992 new
[The use of DNA polymerase from Thermus thermophilus]. A N Kuz'min, V G Kuz'min, V G Morozov Vopr Virusol 1992 new
Detection of viral DNA polymerase activity in salmon tumour tissue induced by herpes virus, Oncorhynchus masou virus. S Suzuki, M Yoshimizu, Mineo Saneyoshi Acta Virol 1992 new
Mammalian DNA polymerase beta can substitute for DNA polymerase I during DNA replication in Escherichia coli. Joann B Sweasy, Lawrence A Loeb The Journal of biological chemistry 1992 pols set
Side chains involved in catalysis of the polymerase reaction of DNA polymerase I from Escherichia coli. A H Polesky, M E Dahlberg, Stephen J Benkovic, Nigel D F Grindley, Catherine M Joyce The Journal of biological chemistry 1992 new
Potential anti-AIDS naphthalenesulfonic acid derivatives. Synthesis and inhibition of HIV-1 induced cytopathogenesis and HIV-1 and HIV-2 reverse transcriptase activities. G T Tan, A Wickramasinghe, S Verma, R Singh, Stephen H Hughes, J M Pezzuto, Masanori Baba, P Mohan Journal of medicinal chemistry 1992 pols set
Studies on the initiation of simian virus 40 replication in vitro: RNA primer synthesis and its elongation. Y Murakami, Toshihiko Eki, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1992 new
Transient expression of the vaccinia virus DNA polymerase is an intrinsic feature of the early phase of infection and is unlinked to DNA replication and late gene expression. W F McDonald, V Crozel-Goudot, Paula Traktman J Virol 1992 pols set
[2',5'-Bis-O-(tert-butyldimethylsilyl)]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) (TSAO) derivatives of purine and pyrimidinenucleosides as potent and selective inhibitors of human immunodeficiency virus type 1. Jan Balzarini, María-Jesús Pérez-Pérez, Ana San-Félix, Sonsoles Velazquez, María-José Camarasa, Erik De Clercq Antimicrobial agents and chemotherapy 1992 pols set
3'-C-branched 2'-deoxy-5-methyluridines: synthesis, enzyme inhibition, and antiviral properties. I I Fedorov, E M Kazmina, N A Novicov, Galina V Gurskaya, A V Bochkarev, M V Jasko, L S Victorova, M K Kukhanova, Jan Balzarini, Erik De Clercq Journal of medicinal chemistry 1992 pols set
Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. V. Primase action regulates the cycle of Okazaki fragment synthesis. C A Wu, E L Zechner, J A Reems, Charles S McHenry, K J Marians The Journal of biological chemistry 1992 new
DNA polymerase beta mutations in human colorectal cancer. Liming Wang, U Patel, L Ghosh, Sanjeev Banerjee Cancer research 1992 new
Functional cloning vectors for use in directional cDNA cloning using cohesive ends produced with T4 DNA polymerase. J L Kuijper, K M Wiren, L D Mathies, C L Gray, F S Hagen Gene 1992 pols set
The effect of in vitro heat exposure on the recovery of nuclear matrix-bound DNA polymerase alpha activity during the different phases of the cell cycle in synchronized HeLa S3 cells. A M Martelli, R S Gilmour, R Bareggi, L Cocco Exp Cell Res 1992 new
Structural relationships between two forms of DNA polymerase epsilon from calf thymus. Gregg Siegal, J J Turchi, C B Jessee, L M Mallaber, Robert A Bambara, T W Myers The Journal of biological chemistry 1992 new
DNA polymerase delta and epsilon holoenzymes from calf thymus. V Podust, V Mikhailov, A Georgaki, Ulrich Hübscher Chromosoma 1992 new
Differential inhibitory effects of TIBO derivatives on different strains of simian immunodeficiency virus. Zeger Debyser, K De Vreese, Rudi Pauwels, N Yamamoto, J Anné, Erik De Clercq, J Desmyter The Journal of general virology 1992 pols set
The sliding clamp of DNA polymerase III holoenzyme encircles DNA. Mike E O'Donnell, John Kuriyan, Xiang-Peng Kong, P T Stukenberg, R Onrust Molecular biology of the cell 1992 new
A Saccharomyces cerevisiae DNA helicase associated with replication factor C. Xincang Li, B L Yoder, Peter M J Burgers The Journal of biological chemistry 1992 new
Characterization of HIV isolates arising after prolonged zidovudine therapy. D L Mayers, F E McCutchan, E E Sanders-Buell, L I Merritt, S Dilworth, A K Fowler, C A Marks, N M Ruiz, Douglas D Richman, C R Roberts J Acquir Immune Defic Syndr 1992 topics set
Cloning of the gene for the 73 kD subunit of the DNA polymerase alpha primase of Drosophila melanogaster. Sue Cotterill, I. Robert Lehman, P McLachlan Nucleic acids research 1992 new
Common features in the interaction of tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one and -thione and 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives with the human immunodeficiency virus type 1 reverse transcriptase. Zeger Debyser, Rudi Pauwels, Masanori Baba, J Desmyter, Erik De Clercq Molecular pharmacology 1992 new
Comparison of HIV-1 and avian myeloblastosis virus reverse transcriptase fidelity on RNA and DNA templates. Hong Yu, Myron F Goodman The Journal of biological chemistry 1992 pols set
Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor. L A Kohlstaedt, Jianhong Wang, J M Friedman, P A Rice, Thomas A Steitz Science 1992 pols set
Structure and function of the bacteriophage T4 DNA polymerase holoenzyme. M C Young, M K Reddy, Peter H von Hippel Biochemistry 1992 complete
Mutations in two cysteine-histidine-rich clusters in adenovirus type 2 DNA polymerase affect DNA binding. I Joung, J A Engler J Virol 1992 new
Metabolism of 4'-azidothymidine. A compound with potent and selective activity against the human immunodeficiency virus. M S Chen, R T Suttmann, J C Wu, E J Prisbe The Journal of biological chemistry 1992 new
Fluorescence energy transfer between the primer and the beta subunit of the DNA polymerase III holoenzyme. Mark A Griep, Charles S McHenry The Journal of biological chemistry 1992 new
Activity of the purified mutagenesis proteins UmuC, UmuD', and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III. M Rajagopalan, Chengping Lu, Roger Woodgate, Mike E O'Donnell, Myron F Goodman, H Echols Proceedings of the National Academy of Sciences of the United States of America 1992 new
Delta-type DNA polymerase characterized from Drosophila melanogaster embryos. V M Peck, E W Gerner, A E Cress Nucleic acids research 1992 new
Evidence favouring the hypothesis of a conserved 3'-5' exonuclease active site in DNA-dependent DNA polymerases. Luis Blanco, Antonio Bernad, Margarita Salas Gene 1992 pols set
The use of Taq DNA polymerase to determine the sequence specificity of DNA damage caused by cis-diamminedichloroplatinum(II), acridine-tethered platinum(II) diammine complexes or two analogues. V Murray, H Motyka, P R England, G Wickham, H H Lee, W A Denny, W D McFadyen The Journal of biological chemistry 1992 pols set
A molecular model of the complete three-dimensional structure of the Klenow fragment of Escherichia coli DNA polymerase I: binding of the dNTP substrate and template-primer. P N Yadav, J S Yadav, Mukund J Modak Biochemistry 1992 pols set
Human DNA polymerases alpha and beta are able to incorporate anti-HIV deoxynucleotides into DNA. William C Copeland, M S Chen, Teresa S-F Wang The Journal of biological chemistry 1992 partial results
In vitro replication of bacteriophage PRD1 DNA. Metal activation of protein-primed initiation and DNA elongation. J Caldentey, Luis Blanco, H Savilahti, D H Bamford, Margarita Salas Nucleic acids research 1992 new
Initiation of phi 29 DNA replication occurs at the second 3' nucleotide of the linear template: a sliding-back mechanism for protein-primed DNA replication. Juan Méndez, Luis Blanco, J A Esteban, Antonio Bernad, Margarita Salas Proceedings of the National Academy of Sciences of the United States of America 1992 new
The DNA polymerase from the archaebacterium Pyrococcus furiosus does not testify for a specific relationship between archaebacteria and eukaryotes. P Forterre Nucleic acids research 1992 topics set
Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine. Z Gu, Q Gao, Xincang Li, Michael A. Parniak, Mark A. Wainberg J Virol 1992 topics set
Mechanism of anti-human immunodeficiency virus action of polyoxometalates, a class of broad-spectrum antiviral agents. N Yamamoto, Dominique Schols, Erik De Clercq, Zeger Debyser, Rudi Pauwels, Jan Balzarini, H Nakashima, Masanori Baba, M Hosoya, Robert Snoeck Molecular pharmacology 1992 pols set
DNA sequencing with dye-labeled terminators and T7 DNA polymerase: effect of dyes and dNTPs on incorporation of dye-terminators and probability analysis of termination fragments. L G Lee, C R Connell, S L Woo, R D Cheng, B F McArdle, Carl W Fuller, N D Halloran, R K Wilson Nucleic acids research 1992 pols set
Murine cytomegalovirus DNA polymerase: purification, characterization and role in the antiviral activity of acyclovir. H Ochiai, K Kumura, Y Minamishima Antiviral Res 1992 new
Streptococcus pneumoniae DNA polymerase I lacks 3'-to-5' exonuclease activity: localization of the 5'-to-3' exonucleolytic domain. A Diaz, M E Pons, S A Lacks, P Lopez Journal of bacteriology 1992 partial results
Metal activation of synthetic and degradative activities of phi 29 DNA polymerase, a model enzyme for protein-primed DNA replication. J A Esteban, Antonio Bernad, Margarita Salas, Luis Blanco Biochemistry 1992 pols set
Mechanism of DNA strand transfer reactions catalyzed by HIV-1 reverse transcriptase. J A Peliska, Stephen J Benkovic Science 1992 new
Molecular cloning of the cDNA for the catalytic subunit of human DNA polymerase delta. C L Yang, Long-Sheng Chang, Peiming Zhang, H Hao, L Zhu, N L Toomey, Marietta Y W T Lee Nucleic acids research 1992 topics set
8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G----T and A----C substitutions. K C Cheng, D S Cahill, Hironori Kasai, Susumu Nishimura, Lawrence A Loeb The Journal of biological chemistry 1992 new
Transposon Tn5 excision in yeast: influence of DNA polymerases alpha, delta, and epsilon and repair genes. Dmitry A Gordenin, A L Malkova, A Peterzen, V N Kulikov, Youri I Pavlov, E Perkins, Michael A Resnick Proceedings of the National Academy of Sciences of the United States of America 1992 topics set
Incorporation of cytosine arabinoside monophosphate into DNA at internucleotide linkages by human DNA polymerase alpha. Fred W Perrino, H L Mekosh The Journal of biological chemistry 1992 topics set
Three new DNA helicases from Saccharomyces cerevisiae. Xincang Li, B L Yoder, Peter M J Burgers Chromosoma 1992 new
The 3'-->5' exonuclease associated with HeLa DNA polymerase epsilon. L Uitto, J Halleen, P Remes, Tapio Kesti, Juhani E Syväoja Chromosoma 1992 pols set
A DNA polymerase from maize axes: its purification and possible role. P Coello, R Rodríquez, E García, J M Vázquez-Ramos Plant Mol Biol 1992 new
Purification and identification of subunit structure of the human mitochondrial DNA polymerase. H Gray, T W Wong The Journal of biological chemistry 1992 new
Binding of DNA to large fragment of DNA polymerase I: identification of strong and weak electrostatic forces and their biological implications. P N Yadav, J S Yadav, Mukund J Modak J Biomol Struct Dyn 1992 pols set
A ganciclovir-resistant clinical isolate of human cytomegalovirus exhibiting cross-resistance to other DNA polymerase inhibitors. W A Tatarowicz, Nell S Lurain, Kenneth D Thompson J Infect Dis 1992 new
Overproduction and purification of Bacillus subtilis DNA polymerase III. R A Hammond, Neal C Brown Protein Expr Purif 1992 new
[Hepatitis B virus DNA polymerase activity in various clinical forms of HBV infection]. T Loch, J Cianciara Pol Arch Med Wewn 1992 new
DNA polymerase beta and DNA synthesis in Xenopus oocytes and in a nuclear extract. T M Jenkins, J K Saxena, A Kumar, Samuel H Wilson, E J Ackerman Science 1992 new
Immunocytochemical identification of proliferative hepatocytes using monoclonal antibody to proliferating cell nuclear antigen (PCNA/cyclin). Comparison with immunocytochemical staining for DNA polymerase-alpha. N Kawakita, S Seki, A Yanai, H Sakaguchi, T Kuroki, Y Mizoguchi, Kazuki Kobayashi, T Monna Am J Clin Pathol 1992 new
Biochemical studies on the reverse transcriptase and RNase H activities from human immunodeficiency virus strains resistant to 3'-azido-3'-deoxythymidine. S F Lacey, J E Reardon, E S Furfine, Thomas A Kunkel, Katarzyna Bebenek, Kristin A Eckert, S D Kemp, Brendan A Larder The Journal of biological chemistry 1992 topics set
Resistance of human immunodeficiency virus type 1 reverse transcriptase to TIBO derivatives induced by site-directed mutagenesis. K De Vreese, Zeger Debyser, Anne-Mieke Vandamme, Rudi Pauwels, J Desmyter, Erik De Clercq, J Anné Virology 1992 pols set
3'-->5' exonuclease in Drosophila mitochondrial DNA polymerase. Substrate specificity and functional coordination of nucleotide polymerization and mispair hydrolysis. M W Olson, Laurie S Kaguni The Journal of biological chemistry 1992 new
Specific HIV-1 reverse transcriptase inhibitors. Zeger Debyser, Rudi Pauwels, Koen Andries, Erik De Clercq Journal of enzyme inhibition 1992 pols set
Conformational coupling in DNA polymerase information transfer. Kenneth A Johnson Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1992 new
Mutations in T7 RNA polymerase that support the proposal for a common polymerase active site structure. G Bonner, D Patra, E M Lafer, R Sousa The EMBO journal 1992 new
Are there highly conserved DNA polymerase 3'----5' exonuclease motifs? Linda J Reha-Krantz Gene 1992 complete
Human DNA polymerase delta gene maps to region 19q13.3-q13.4 by in situ hybridization. R R Kemper, E R Ahn, Peiming Zhang, Marietta Y W T Lee, M Rabin Genomics 1992 pols set
Kinetics of inhibition of endogenous human immunodeficiency virus type 1 reverse transcription by 2',3'-dideoxynucleoside 5'-triphosphate, tetrahydroimidazo-[4,5,1-jk][1,4]-benzodiazepin-2(1H)-thion e, and 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives. Zeger Debyser, Anne-Mieke Vandamme, Rudi Pauwels, Masanori Baba, J Desmyter, Erik De Clercq The Journal of biological chemistry 1992 pols set
A DNA polymerase alpha pause site is a hot spot for nucleotide misinsertion. M Fry, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1992 new
Structural and functional relationships of human DNA polymerases. H Hao, Yanan Jiang, S J Zhang, Peiming Zhang, R X Zeng, Marietta Y W T Lee Chromosoma 1992 pols set
African swine fever virus-induced DNA polymerase is resistant to aphidicolin. M I Marques, J V Costa Virology 1992 new
CircumVent thermal cycle sequencing and alternative manual and automated DNA sequencing protocols using the highly thermostable VentR (exo-) DNA polymerase. L E Sears, L S Moran, C Kissinger, T Creasey, H Perry-O'Keefe, M Roskey, E Sutherland, B E Slatko BioTechniques 1992 topics set
Inhibition of DNA polymerase activity by thymine hydrates. T Ganguly, N J Duker Mutation research 1992 pols set
Parameters that influence processive synthesis and site-specific termination by human immunodeficiency virus reverse transcriptase on RNA and DNA templates. J J DeStefano, R G Buiser, L M Mallaber, P J Fay, Robert A Bambara Biochimica et biophysica acta 1992 partial results
In vitro selection and molecular characterization of human immunodeficiency virus-1 resistant to non-nucleoside inhibitors of reverse transcriptase. John W Mellors, Ginger E Dutschman, G J Im, Enzo Tramontano, S R Winkler, Yung-Chi Cheng Mol Pharmacol 1992 topics set
Asp537, Asp812 are essential and Lys631, His811 are catalytically significant in bacteriophage T7 RNA polymerase activity. P A Osumi-Davis, M C de Aguilera, R W Woody, A Y Woody Journal of molecular biology 1992 new
Inhibitors of HIV-1 reverse transcriptase and fidelity of in vitro DNA replication. J Abbotts, Samuel H Wilson Journal of enzyme inhibition 1992 pols set
Sequence and expression in Escherichia coli of the 40-kDa subunit of activator 1 (replication factor C) of HeLa cells. M Chen, Z Q Pan, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1992 new
A comparison of the fidelity of copying 5-methylcytosine and cytosine at a defined DNA template site. J C Shen, S Creighton, P A Jones, Myron F Goodman Nucleic acids research 1992 new
Developmental activity profile of DNA polymerases delta and alpha in rat neurons suggests a coordinated in vivo function. Silvio Spadari, Federico Focher, Ulrich Hübscher In vivo (Athens, Greece) 1992 topics set
DNA helicase E and DNA polymerase epsilon functionally interact for displacement synthesis. J J Turchi, Gregg Siegal, Robert A Bambara Biochemistry 1992 new
Minimal kinetic mechanism for misincorporation by DNA polymerase I (Klenow fragment). B T Eger, Stephen J Benkovic Biochemistry 1992 new
Comparative Physiological Studies on Hyperthermophilic Archaea Isolated from Deep-Sea Hot Vents with Emphasis on Pyrococcus Strain GB-D. H W Jannasch, C O Wirsen, S J Molyneaux, T A Langworthy Appl Environ Microbiol 1992 pols set
Protein-protein interactions at a DNA replication fork: bacteriophage T4 as a model. Nancy G Nossal FASEB J 1992 complete
Differential susceptibilities of U-937 cell clones to infection by human immunodeficiency virus type 1. F Boulerice, R Geleziunas, S Bour, H L Li, M D'Addario, A Roulston, J Hiscott, Mark A. Wainberg Journal of virology 1992 pols set
Physical mapping of loci in the distal half of the short arm of the human X chromosome: implications for the spreading of X-chromosome inactivation. J C Wang, M B Passage, J Ellison, M A Becker, P H Yen, L J Shapiro, T K Mohandas Somatic cell and molecular genetics 1992 new
Anti-human immunodeficiency virus effects of cationic metalloporphyrin-ellipticine complexes. L Ding, Jan Balzarini, Dominique Schols, B Meunier, Erik De Clercq Biochemical pharmacology 1992 pols set
Expression of the signal transducing regions of CD4-like and lck genes in murine egg. T Mori, M W Gou, Hiromi Yoshida, S Saito, E Mori Biochemical and biophysical research communications 1992 new
Base mispair extension kinetics. Binding of avian myeloblastosis reverse transcriptase to matched and mismatched base pair termini. S Creighton, M M Huang, H Cai, Norman Arnheim, Myron F Goodman The Journal of biological chemistry 1992 new
DNA polymerase epsilon: in search of a function. Ulrich Hübscher, P Thömmes Trends in biochemical sciences 1992 new
The separated enantiomers of 2'-deoxy-3'-thiacytidine (BCH 189) both inhibit human immunodeficiency virus replication in vitro. J A Coates, Nick Cammack, H J Jenkinson, I M Mutton, B A Pearson, R Storer, J M Cameron, C R Penn Antimicrob Agents Chemother 1992 topics set
In vitro DNA synthesis by DNA polymerase I and DNA polymerase alpha on single-stranded DNA containing either purine or pyrimidine monoadducts. Jean-Sébastien Hoffmann, E Moustacchi, Giuseppe Villani, E Sage Biochem Pharmacol 1992 pols set
Kinetic characterization of the polymerase and exonuclease activities of the gene 43 protein of bacteriophage T4. T L Capson, J A Peliska, B F Kaboord, M W Frey, C Lively, M Dahlberg, Stephen J Benkovic Biochemistry 1992 topics set
Variable tRNA content in HIV-1IIIB. M Jiang, J Mak, Mark A. Wainberg, Michael A. Parniak, E Cohen, Lawrence Kleiman Biochemical and biophysical research communications 1992 pols set
Effect of the (+)-CC-1065-(N3-adenine)DNA adduct on in vitro DNA synthesis mediated by Escherichia coli DNA polymerase. Daekyu Sun, Laurence H Hurley Biochemistry 1992 pols set
Protein affinity chromatography with purified yeast DNA polymerase alpha detects proteins that bind to DNA polymerase. J Miles, T Formosa Proceedings of the National Academy of Sciences of the United States of America 1992 new
Isothermal in vitro amplification of DNA by a restriction enzyme/DNA polymerase system. G T Walker, M C Little, J G Nadeau, D D Shank Proceedings of the National Academy of Sciences of the United States of America 1992 pols set
Strategies in the treatment of AIDS and related diseases: the lessons of cancer chemotherapy. Mark A. Wainberg, R G Margolese Cancer investigation 1992 pols set
Effects of different DNA polymerases in ligation-mediated PCR: enhanced genomic sequencing and in vivo footprinting. P A Garrity, B J Wold Proceedings of the National Academy of Sciences of the United States of America 1992 topics set
DNA polymerase alpha, beta, and gamma activities in human lymphocytes stimulated by Tora-mame (Phaseolus vulgaris) lectin. H Umekawa, K Kondoh, Yasuhiro Furuichi, Tomonori Takahashi, Shonen Yoshida Biochem Int 1992 new
Modified T7 DNA polymerase for DNA sequencing. Carl W Fuller Methods in enzymology 1992 pols set
Differential action and differential expression of DNA polymerase I during Escherichia coli colony development. J A Shapiro J Bacteriol 1992 new
Phi 29 DNA polymerase active site. Mutants in conserved residues Tyr254 and Tyr390 are affected in dNTP binding. M A Blasco, José María Lázaro, Antonio Bernad, Luis Blanco, Margarita Salas The Journal of biological chemistry 1992 pols set
Genetic analysis of the interaction between bacteriophage T7 DNA polymerase and Escherichia coli thioredoxin. J S Himawan, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 1992 pols set
Processive proofreading is intrinsic to T4 DNA polymerase. M K Reddy, S E Weitzel, Peter H von Hippel The Journal of biological chemistry 1992 complete
HIV-1 and HIV-2 reverse transcriptases: a comparative study of sensitivity to inhibition by selected natural products. G T Tan, J F Miller, A D Kinghorn, Stephen H Hughes, J M Pezzuto Biochemical and biophysical research communications 1992 pols set
The fidelity of Taq polymerase catalyzing PCR is improved by an N-terminal deletion. Wayne M Barnes Gene 1992 topics set
Altered expression of adenovirus 12 DNA-binding protein but not DNA polymerase during abortive infection of hamster cells. L A Lucher, B Khuntirat, J Zhao, P C Angeletti Virology 1992 new
Recognition of the adenovirus type 2 origin of DNA replication by the virally encoded DNA polymerase and preterminal proteins. S M Temperley, R T Hay The EMBO journal 1992 new
Purification of a mitochondrial DNA polymerase from Crithidia fasciculata. A F Torri, Paul T Englund The Journal of biological chemistry 1992 new
Fidelity of the reverse transcriptase of human immunodeficiency virus type 2. M Bakhanashvili, A Hizi FEBS letters 1992 partial results
The effects of cysteine mutations on the catalytic activities of the reverse transcriptase of human immunodeficiency virus type-1. S Loya, R Tal, Stephen H Hughes, A Hizi The Journal of biological chemistry 1992 pols set
Interactions of gene 2.5 protein and DNA polymerase of bacteriophage T7. Y T Kim, Stanley Tabor, J E Churchich, Charles C Richardson The Journal of biological chemistry 1992 pols set
Nucleoprotein complexes released from lymphoma nuclei that contain the abl oncogene and RNA and DNA polymerase and RNA primase activities. N L Rosenberg-Nicolson, G L Nicolson J Cell Biochem 1992 new
PCNA-dependent DNA polymerase delta from rabbit bone marrow. C D Lu, J J Byrnes Biochemistry 1992 new
Immunization with soluble protein-pulsed spleen cells induces class I-restricted cytotoxic T lymphocytes that recognize immunodominant epitopic peptides from Plasmodium falciparum and HIV-1. A Hosmalin, S Kumar, D Barnd, R Houghten, G E Smith, Stephen H Hughes, J A Berzofsky Journal of immunology (Baltimore, Md. : 1950) 1992 pols set
Selective inhibition of the 3'-to-5' exonuclease activity associated with Epstein-Barr virus DNA polymerase by ribonucleoside 5'-monophosphates. Tatsuya Tsurumi Virology 1992 new
Unequal human immunodeficiency virus type 1 reverse transcriptase error rates with RNA and DNA templates. J C Boyer, Katarzyna Bebenek, Thomas A Kunkel Proceedings of the National Academy of Sciences of the United States of America 1992 pols set
DNA polymerase, RNA polymerase and exonuclease activities on a DNA sequence modified by benzo[a]pyrene diolepoxide. B D Thrall, D B Mann, M J Smerdon, D L Springer Carcinogenesis 1992 new
Localization of the exonuclease and polymerase domains of Bacillus subtilis DNA polymerase III. Marjorie H Barnes, R A Hammond, C C Kennedy, S L Mack, Neal C Brown Gene 1992 new
The effects of dNTP pool imbalances on frameshift fidelity during DNA replication. Katarzyna Bebenek, J D Roberts, Thomas A Kunkel The Journal of biological chemistry 1992 new
DNA polymerase action on benzo[a]pyrene-DNA adducts. A M Hruszkewycz, K A Canella, K Peltonen, L Kotrappa, A Dipple Carcinogenesis 1992 new
Involvement of DNA polymerase beta in proliferation of rat liver induced by lead nitrate or partial hepatectomy. M Menegazzi, A Carcereri de Prati, T Ogura, A Columbano, G M Ledda-Columbano, M Libonati, H Esumi, Hiroshi Suzuki FEBS letters 1992 new
Accessory protein function in the DNA polymerase III holoenzyme from E. coli. Mike E O'Donnell Bioessays 1992 pols set
Reverse transcriptase of human immunodeficiency virus can use either human tRNA(3Lys) or Escherichia coli tRNA(2Gln) as a primer in an in vitro primer-utilization assay. L A Kohlstaedt, Thomas A Steitz Proceedings of the National Academy of Sciences of the United States of America 1992 pols set
Purification and properties of DNA polymerase from Bacillus caldotenax. J A Burrows, C R Goward Biochem J 1992 topics set
Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. IV. Reconstitution of an asymmetric, dimeric DNA polymerase III holoenzyme. C A Wu, E L Zechner, A J Hughes, M A Franden, Charles S McHenry, K J Marians The Journal of biological chemistry 1992 pols set
DNA polymerase-beta and poly(ADP)ribose polymerase mRNAs are differentially expressed during the development of male germinal cells. A A Alcivar, L E Hake, N B Hecht Biol Reprod 1992 new
Aphidicolin inhibits DNA polymerizing activity but not nucleolytic activity of Escherichia coli DNA polymerase II. Yoshizumi Ishino, Hiroshi Iwasaki, H Fukui, J Mineno, Ikunoshin Kato, Hideo Shinagawa Biochimie 1992 pols set
Protein splicing removes intervening sequences in an archaea DNA polymerase. R A Hodges, F B Perler, C J Noren, William E Jack Nucleic acids research 1992 complete William E Jack*
DNA polymerase I modulates inducible stable DNA replication in Escherichia coli. T Ruscitti, Stuart Linn J Bacteriol 1992 new
Prevention of the spread of HIV-1 infection with nonnucleoside reverse transcriptase inhibitors. M B Vasudevachari, C Battista, H C Lane, M C Psallidopoulos, B Zhao, J Cook, J R Palmer, D L Romero, W G Tarpley, N P Salzman Virology 1992 pols set
Inhibition of herpes simplex virus type 1 DNA polymerase by the natural product oosporein. B J Terry, W C Liu, C W Cianci, E Proszynski, P Fernandes, K Bush, E Meyers J Antibiot (Tokyo) 1992 new
The replication of DNA containing the simian virus 40 origin by the monopolymerase and dipolymerase systems. Toshihiko Eki, T Matsumoto, Y Murakami, Jerard Hurwitz The Journal of biological chemistry 1992 new
[A method of isolation and properties of DNA-dependent DNA-polymerase epsilon from human placenta]. D Iu Mozzherin, A M Atrazhev, M K Kukhanova Mol Biol (Mosk) 1992 new
Studies of the cloned 37-kDa subunit of activator 1 (replication factor C) of HeLa cells. M Chen, Z Q Pan, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1992 new
Intervening sequences in an Archaea DNA polymerase gene. F B Perler, D G Comb, William E Jack, L S Moran, B Qiang, R B Kucera, J Benner, B E Slatko, D O Nwankwo, S K Hempstead Proceedings of the National Academy of Sciences of the United States of America 1992 partial results
Inhibitory effects of 2'-deoxy-5-styryluridine 5'-triphosphate analogs on retroviral reverse transcriptase and eukaryotic DNA polymerases. Tsuyoshi Yamaguchi, Shunji Izuta, Motoshi Suzuki, Shonen Yoshida, Akio Matsukage, Mineo Saneyoshi Nucleic acids symposium series 1992 pols set
Allosteric inhibition of human immunodeficiency virus type 1 reverse transcriptase by tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one and -thione compounds. Zeger Debyser, Rudi Pauwels, Koen Andries, J Desmyter, Y Engelborghs, Paul A J Janssen, Erik De Clercq Molecular pharmacology 1992 pols set
Distribution of DNA polymerase alpha during nuclear division cycles in Drosophila melanogaster embryo. Masamitsu Yamaguchi, Kazufumi Kuroda, Fumiko Hirose, Akio Matsukage Cell structure and function 1992 new
DNA polymerase II, the probable homolog of mammalian DNA polymerase epsilon, replicates chromosomal DNA in the yeast Saccharomyces cerevisiae. Hiroyuki Araki, P A Ropp, A L Johnson, L H Johnston, A Morrison, Akio Sugino The EMBO journal 1992 topics set
Mechanism of action of foscarnet against viral polymerases. C S Crumpacker Am J Med 1992 topics set
Physical and functional interaction of human cytomegalovirus DNA polymerase and its accessory protein (ICP36) expressed in insect cells. P F Ertl, K L Powell J Virol 1992 pols set
HeLa cell single-stranded DNA-binding protein increases the accuracy of DNA synthesis by DNA polymerase alpha in vitro. Michael P Carty, A S Levine, K Dixon Mutation research 1992 new
New perspectives for the chemotherapy and chemoprophylaxis of AIDS (acquired immune deficiency syndrome). Erik De Clercq Verhandelingen - Koninklijke Academie voor Geneeskunde van België 1992 pols set
Mammalian DNA polymerase beta: characterization of a 16-kDa transdomain fragment containing the nucleic acid-binding activities of the native enzyme. J R Casas-Finet, A Kumar, R L Karpel, Samuel H Wilson Biochemistry 1992 pols set
Identification of the primer binding domain in human immunodeficiency virus reverse transcriptase. A Basu, K K Ahluwalia, S Basu, Mukund J Modak Biochemistry 1992 pols set
Processive DNA synthesis by DNA polymerase II mediated by DNA polymerase III accessory proteins. C A Bonner, P T Stukenberg, M Rajagopalan, R Eritja, Mike E O'Donnell, K McEntee, H Echols, Myron F Goodman The Journal of biological chemistry 1992 partial results
HIV inhibitors targeted at the reverse transcriptase. Erik De Clercq AIDS research and human retroviruses 1992 pols set
Use of suppressor analysis to identify DNA polymerase mutations in herpes simplex virus which affect deoxynucleoside triphosphate substrate specificity. Y S Wang, S Woodward, J D Hall J Virol 1992 new
(-)-2'-deoxy-3'-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitro. J A Coates, Nick Cammack, H J Jenkinson, A J Jowett, M I Jowett, B A Pearson, C R Penn, P L Rouse, K C Viner, J M Cameron Antimicrob Agents Chemother 1992 topics set
Structure-activity analyses of HIV-1 reverse transcriptase. A Basu, S Basu, Mukund J Modak Biochemical and biophysical research communications 1992 pols set
Human immunodeficiency virus reverse transcriptase: steady-state and pre-steady-state kinetics of nucleotide incorporation. J E Reardon Biochemistry 1992 pols set
Site-directed mutagenesis at the Exo III motif of phi 29 DNA polymerase; overlapping structural domains for the 3'-5' exonuclease and strand-displacement activities. M S Soengas, J A Esteban, José María Lázaro, Antonio Bernad, M A Blasco, Margarita Salas, Luis Blanco The EMBO journal 1992 pols set
PCNA-induced DNA synthesis past cis-syn and trans-syn-I thymine dimers by calf thymus DNA polymerase delta in vitro. C L O'Day, Peter M J Burgers, John-Stephen Taylor Nucleic acids research 1992 new
Reverse transcriptase of human immunodeficiency virus type 1: functionality of subunits of the heterodimer in DNA synthesis. Z Hostomsky, Z Hostomska, T B Fu, J Taylor J Virol 1992 pols set
Structure-function analysis of DNA polymerase-beta using monoclonal antibodies: identification of a putative nucleotide binding domain. A J Recupero, D C Rein, R R Meyer Biochemistry 1992 new
Mechanism and fidelity of HIV reverse transcriptase. W M Kati, Kenneth A Johnson, L F Jerva, Karen S Anderson The Journal of biological chemistry 1992 topics set
Preparation and anti-HIV activities of aurintricarboxylic acid fractions and analogues: direct correlation of antiviral potency with molecular weight. Mark Cushman, P L Wang, S H Chang, C Wild, Erik De Clercq, Dominique Schols, M E Goldman, J A Bowen Journal of medicinal chemistry 1991 pols set
Proofreading activity of DNA polymerase III responds like elongation activity to auxiliary subunits. J A Reems, Mark A Griep, Charles S McHenry The Journal of biological chemistry 1991 pols set
Human placenta DNA primase: purification of enzyme and analysis of RNA primer synthesis. Vladimir N Podust, O V Vladimirova, Olga I Lavrik Biochemistry international 1991 new
Reverse transcriptase.RNase H from the human immunodeficiency virus. Relationship of the DNA polymerase and RNA hydrolysis activities. E S Furfine, J E Reardon The Journal of biological chemistry 1991 partial results
Cell cycle-dependent biosynthesis of Plasmodium falciparum DNA polymerase-alpha. I Choi, R B Mikkelsen Exp Parasitol 1991 new
Producing single-stranded DNA probes with the Taq DNA polymerase: a high yield protocol. U Finckh, P A Lingenfelter, D Myerson BioTechniques 1991 pols set
Enzymologic mechanism of calf thymus DNA polymerase delta. L Ng, Cheng-Keat Tan, Kathleen M Downey, Paul A Fisher The Journal of biological chemistry 1991 new
Chemotherapy of the acquired immune deficiency syndrome (AIDS): acyclic nucleoside phosphonate analogues. Erik De Clercq International journal of immunopharmacology 1991 new
Escherichia coli DNA polymerase II is homologous to alpha-like DNA polymerases. Hiroshi Iwasaki, Yoshizumi Ishino, H Toh, A Nakata, Hideo Shinagawa Mol Gen Genet 1991 pols set
An induced-fit kinetic mechanism for DNA replication fidelity: direct measurement by single-turnover kinetics. I Wong, Smita S Patel, Kenneth A Johnson Biochemistry 1991 pols set
The mechanism of recognition of templates by DNA polymerases from pro- and eukaryotes as revealed by affinity modification data. T I Kolocheva, G A Nevinsky, A S Levina, V V Khomov, Olga I Lavrik Journal of biomolecular structure & dynamics 1991 pols set
Regulation of DNA polymerase alpha activity by the alpha 1-adrenergic receptors in proliferatively activated rat liver cells. Neus Agell, M J Pujol, E Rius, Oriol Bachs Biochem Biophys Res Commun 1991 new
A constant rate of spontaneous mutation in DNA-based microbes. John W Drake Proceedings of the National Academy of Sciences of the United States of America 1991 partial results
On the association of DNA polymerase alpha activity with the nuclear matrix in HeLa cells. A M Martelli, L Cocco, F A Manzoli Cell Biol Int Rep 1991 new
Variation in simian immunodeficiency virus env is confined to V1 and V4 during progression to simian AIDS. J Overbaugh, L M Rudensey, M D Papenhausen, R E Benveniste, W R Morton J Virol 1991 new
Properties of the 3' to 5' exonuclease associated with porcine liver DNA polymerase gamma. Substrate specificity, product analysis, inhibition, and kinetics of terminal excision. Matthew J Longley, D W Mosbaugh The Journal of biological chemistry 1991 new
Overexpression, purification, and characterization of Escherichia coli bacteriophage PRD1 DNA polymerase. In vitro synthesis of full-length PRD1 DNA with purified proteins. H Savilahti, J Caldentey, K Lundström, Juhani E Syväoja, D H Bamford The Journal of biological chemistry 1991 new
The fidelity of DNA synthesis by the catalytic subunit of yeast DNA polymerase alpha alone and with accessory proteins. Thomas A Kunkel, J D Roberts, Akio Sugino Mutation research 1991 pols set
Purification and characterization of a gamma-like DNA polymerase from Chlamydomonas reinhardtii. Z F Wang, Jingsong Yang, Z Q Nie, Min Wu Biochemistry 1991 new
Clinical significance and characterization of AZT-resistant strains of HIV-1. Mark A. Wainberg, R Rooke, M Tremblay, Xincang Li, Michael A. Parniak, Q Gao, X J Yao, C Tsoukas, J Montaner, M Fanning, J Ruedy The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses 1991 pols set
Mutational analysis of the DNA polymerase and ribonuclease H activities of human immunodeficiency virus type 2 reverse transcriptase expressed in Escherichia coli. A Hizi, R Tal, Stephen H Hughes Virology 1991 pols set
Analysis of the ATPase subassembly which initiates processive DNA synthesis by DNA polymerase III holoenzyme. R Onrust, P T Stukenberg, Mike E O'Donnell The Journal of biological chemistry 1991 new
Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture. D Richman, C K Shih, I Lowy, J Rose, P Prodanovich, S Goff, J Griffin Proceedings of the National Academy of Sciences of the United States of America 1991 topics set
Development and DNA polymerase activities in cultured preimplantation mouse embryos: comparison with embryos developed in vivo. A A Kiessling, H W Davis, C S Williams, R W Sauter, L W Harrison J Exp Zool 1991 new
The destiny of reverse transcriptase anatomy. Stephen H Hughes Current biology : CB 1991 new
Inhibition of the growth of Plasmodium falciparum and Plasmodium berghei by the DNA polymerase inhibitor HPMPA. E de Vries, J G Stam, F F Franssen, H Nieuwenhuijs, P Chavalitshewinkoon, Erik De Clercq, J P Overdulve, Peter C van der Vliet Mol Biochem Parasitol 1991 new
Organization of mouse DNA polymerase beta gene silencer elements and identification of the silencer-binding factor(s). Masamitsu Yamaguchi, Y Hayashi, K Furukawa, Y Nishimoto, Akio Matsukage Jpn J Cancer Res 1991 new
Optimization of the polymerase chain reaction with regard to fidelity: modified T7, Taq, and vent DNA polymerases. L L Ling, P Keohavong, C Dias, William G Thilly PCR methods and applications 1991 partial results
Recovery of infectious human immunodeficiency virus type 1 after fusion of defectively infected clones of U-937 cells. F Boulerice, X G Li, A Lvovich, Mark A. Wainberg Journal of virology 1991 pols set
Specific inhibition of human DNA ligase adenylation by a distamycin derivative possessing antitumor activity. Alessandra Montecucco, M Fontana, Federico Focher, M Lestingi, Silvio Spadari, G Ciarrocchi Nucleic acids research 1991 topics set
The T4 DNA polymerase accessory proteins form an ATP-dependent complex on a primer-template junction. M M Munn, B M Alberts The Journal of biological chemistry 1991 complete
Fidelity of Thermococcus litoralis DNA polymerase (Vent) in PCR determined by denaturing gradient gel electrophoresis. N F Cariello, James A Swenberg, T R Skopek Nucleic acids research 1991 complete
Fidelity of DNA synthesis by the Thermococcus litoralis DNA polymerase--an extremely heat stable enzyme with proofreading activity. P Mattila, J Korpela, T Tenkanen, K Pitkänen Nucleic acids research 1991 partial results
HP 0.35, a cephalosporin degradation product is a specific inhibitor of lentiviral RNAses H. P Hafkemeyer, K Neftel, R Hobi, A Pfaltz, H Lutz, K Lüthi, Federico Focher, Silvio Spadari, Ulrich Hübscher Nucleic acids research 1991 partial results
5'-derivatives of oligonucleotides as primers of DNA polymerization catalyzed by AMV reverse transcriptase and Klenow fragment of DNA polymerase 1. I A Lokhova, G A Nevinsky, T S Godovikova, E M Ivanova, A A Koshkin, D S Sergeev, E I Frolova, N K Rudenko, V V Khomov, V M Kavsan FEBS letters 1991 pols set
Origin of adeno-associated virus DNA replication is a target of carcinogen-inducible DNA amplification. A O Yalkinoglu, H Zentgraf, Ulrich Hübscher Journal of virology 1991 new
Identification and functional characterization of Epstein-Barr virus DNA polymerase by in vitro transcription-translation of a cloned gene. J C Lin, N D Sista, F Besençon, J Kamine, J S Pagano J Virol 1991 pols set
Reverse transcription and DNA amplification by a Thermus thermophilus DNA polymerase. T W Myers, D H Gelfand Biochemistry 1991 partial results
Detection of specific polymerase chain reaction product by utilizing the 5'----3' exonuclease activity of Thermus aquaticus DNA polymerase. P M Holland, R D Abramson, R Watson, D H Gelfand Proceedings of the National Academy of Sciences of the United States of America 1991 new
Genetic characterization of the vaccinia virus DNA polymerase: identification of point mutations conferring altered drug sensitivities and reduced fidelity. J A Taddie, Paula Traktman J Virol 1991 pols set
Correct intranuclear localization of herpes simplex virus DNA polymerase requires the viral ICP8 DNA-binding protein. M Bush, D R Yager, M Gao, Klaus Weisshart, A I Marcy, Donald M Coen, David M Knipe J Virol 1991 new
Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase. M H St Clair, J L Martin, G Tudor-Williams, M C Bach, C L Vavro, D M King, P Kellam, S D Kemp, Brendan A Larder Science 1991 topics set
Mechanism of DNA polymerase alpha inhibition by aphidicolin. R Sheaff, D Ilsley, R Kuchta Biochemistry 1991 new
Kinetic mechanism of DNA polymerase I (Klenow fragment): identification of a second conformational change and evaluation of the internal equilibrium constant. M E Dahlberg, Stephen J Benkovic Biochemistry 1991 pols set
Effect of activators and inhibitors on the activity of mitochondrial DNA polymerase. J Grones Folia Microbiol (Praha) 1991 new
Endogenous mutations and cancer. T M Reid, M Fry, Lawrence A Loeb Princess Takamatsu Symp 1991 new
Catalytic subunit of human DNA polymerase alpha overproduced from baculovirus-infected insect cells. Structural and enzymological characterization. William C Copeland, Teresa S-F Wang The Journal of biological chemistry 1991 pols set
Polymerization activity of an alpha-like DNA polymerase requires a conserved 3'-5' exonuclease active site. J S Gibbs, Klaus Weisshart, P Digard, A deBruynKops, David M Knipe, Donald M Coen Molecular and cellular biology 1991 new
Cell cycle-specific expression and nuclear binding of DNA polymerase alpha. T Stokke, B Erikstein, H Holte, S Funderud, H B Steen Molecular and cellular biology 1991 new
Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. T Weiser, M Gassmann, P Thömmes, Elena Ferrari, P Hafkemeyer, Ulrich Hübscher The Journal of biological chemistry 1991 partial results
The molecular mechanism of inhibition of alpha-type DNA polymerases by N2-(butylphenyl)dGTP and 2-(butylanilino)dATP: variation in susceptibility to polymerization. N N Khan, George E Wright, Neal C Brown Nucleic acids research 1991 topics set
Zidovudine-resistant human immunodeficiency virus selected by passage in cell culture. Brendan A Larder, K E Coates, S D Kemp Journal of virology 1991 pols set
Interaction of DNA with the Klenow fragment of DNA polymerase I studied by time-resolved fluorescence spectroscopy. C R Guest, R A Hochstrasser, C G Dupuy, D J Allen, Stephen J Benkovic, David P Millar Biochemistry 1991 pols set
Constitution of the twin polymerase of DNA polymerase III holoenzyme. P S Studwell-Vaughan, Mike E O'Donnell The Journal of biological chemistry 1991 new
Levels of chromosomally encoded Umu proteins and requirements for in vivo UmuD cleavage. Roger Woodgate, D G Ennis Molecular & general genetics : MGG 1991 new
Primer terminus recognition and highly processive replication by Epstein-Barr virus DNA polymerase. Tatsuya Tsurumi Biochem J 1991 pols set
Differential expression of poly(ADP-ribose) polymerase and DNA polymerase beta in rat tissues. M Menegazzi, G Grassi-Zucconi, A Carcerero De Prati, T Ogura, P Poltronieri, H Nyunoya, Y Shiratori-Nyunoya, M Miwa, Hiroshi Suzuki Exp Cell Res 1991 new
Isolation and characterization of a dideoxyguanosine triphosphate-resistant mutant of human immunodeficiency virus reverse transcriptase. Vinayaka R Prasad, I Lowy, T de los Santos, L Chiang, S P Goff Proceedings of the National Academy of Sciences of the United States of America 1991 pols set
Organic solvents as facilitators of polymerase chain reaction. D Pomp, J F Medrano BioTechniques 1991 new
Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity. A Morrison, J B Bell, Thomas A Kunkel, Akio Sugino Proceedings of the National Academy of Sciences of the United States of America 1991 pols set
Characterization of 3'-to 5'-exonuclease activity associated with Epstein-Barr virus DNA polymerase. Tatsuya Tsurumi Virology 1991 partial results
Mutational analysis of the mRNA operator for T4 DNA polymerase. M D Andrake, Jim D Karam Genetics 1991 complete
Factors contributing to the inhibition of HIV reverse transcriptase by chain-terminating nucleotides in vitro and in vivo. R S Goody, B Müller, Tobias Restle FEBS letters 1991 topics set
Random mutagenesis of gene-sized DNA molecules by use of PCR with Taq DNA polymerase. Y H Zhou, X P Zhang, R H Ebright Nucleic acids research 1991 pols set
Possible involvement of the yeast POLIII DNA polymerase in induced gene conversion. F Fabre, A Boulet, G Faye Mol Gen Genet 1991 new
Escherichia coli DNA polymerase II is stimulated by DNA polymerase III holoenzyme auxiliary subunits. A J Hughes, S K Bryan, H Chen, Robb E Moses, Charles S McHenry The Journal of biological chemistry 1991 pols set
Rapid filter assay for the detection of DNA polymerase activity: direct identification of the gene for the DNA polymerase from Thermus aquaticus. G Sagner, R Rüger, C Kessler Gene 1991 new
The 3' to 5' exonuclease activity located in the DNA polymerase delta subunit of Saccharomyces cerevisiae is required for accurate replication. M Simon, L Giot, G Faye The EMBO journal 1991 partial results
Kinetic partitioning between the exonuclease and polymerase sites in DNA error correction. M J Donlin, Smita S Patel, Kenneth A Johnson Biochemistry 1991 pols set
The 3'-5' exonuclease of DNA polymerase I of Escherichia coli: contribution of each amino acid at the active site to the reaction. V Derbyshire, Nigel D F Grindley, Catherine M Joyce The EMBO journal 1991 complete
Sequence-dependent termination of mammalian DNA polymerase reaction by a new platinum compound, (-)-(R)-2-aminomethylpyrrolidine(1,1-cyclobutane-dicarboxylato)-2-plati num(II) monohydrate). M Iwata, Shunji Izuta, Motoshi Suzuki, K Kojima, Y Furuhashi, Y Tomoda, Shonen Yoshida Japanese journal of cancer research : Gann 1991 new
The Trypanosoma brucei DNA polymerase alpha core subunit gene is developmentally regulated and linked to a constitutively expressed open reading frame. P A Leegwater, M Strating, N B Murphy, R F Kooy, Peter C van der Vliet, J P Overdulve Nucleic acids research 1991 pols set
An antiviral target on reverse transcriptase of human immunodeficiency virus type 1 revealed by tetrahydroimidazo-[4,5,1-jk] [1,4]benzodiazepin-2 (1H)-one and -thione derivatives. Zeger Debyser, Rudi Pauwels, Koen Andries, J Desmyter, Michael Kukla, Paul A J Janssen, Erik De Clercq Proceedings of the National Academy of Sciences of the United States of America 1991 topics set
The ATF/CREB transcription factor-binding site in the polymerase beta promoter mediates the positive effect of N-methyl-N'-nitro-N-nitrosoguanidine on transcription. Padmini S Kedar, S G Widen, E W Englander, A J Fornace, Samuel H Wilson Proceedings of the National Academy of Sciences of the United States of America 1991 new
The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli. K C Cheng, Bradley D Preston, D S Cahill, M K Dosanjh, B Singer, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1991 new
Purification and partial characterization of equine infectious anemia virus reverse transcriptase. A DeVico, R C Montelaro, R C Gallo, M G Sarngadharan Virology 1991 partial results
Labelling DNA ends with the Klenow fragment of the E. coli DNA polymerase I: a cautionary note. G del Solar, M Espinosa Nucleic acids research 1991 pols set
Induction of DNA polymerase activities in the regenerating rat liver. C L Yang, S J Zhang, N L Toomey, T N Palmer, Marietta Y W T Lee Biochemistry 1991 new
Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism. Lorena S Beese, Thomas A Steitz The EMBO journal 1991 complete
The p15 carboxyl-terminal proteolysis product of the human immunodeficiency virus type 1 reverse transcriptase p66 has DNA polymerase activity. P Hafkemeyer, Elena Ferrari, J Brecher, Ulrich Hübscher Proceedings of the National Academy of Sciences of the United States of America 1991 new
Eukaryotic DNA primase. Abortive synthesis of oligoadenylates. Vladimir N Podust, O V Vladimirova, E N Manakova, Olga I Lavrik FEBS letters 1991 new
Differential inhibition of retroviral reverse transcriptase by poly(2-fluoroadenylic acid), a template analogue. K Kohda, H Ukai, Jan Balzarini, Erik De Clercq, P F Torrence AIDS (London, England) 1991 new
Aspartic acid residues at positions 190 and 192 of rat DNA polymerase beta are involved in primer binding. T Date, S Yamamoto, K Tanihara, Y Nishimoto, Akio Matsukage Biochemistry 1991 new
Oligonucleotides and their derivatives as tools for investigations of protein-nucleic acid interactions in template biocatalysis. Olga I Lavrik Nucleic acids symposium series 1991 pols set
Isolation of foscarnet-resistant human cytomegalovirus patterns of resistance and sensitivity to other antiviral drugs. V Sullivan, Donald M Coen The Journal of infectious diseases 1991 new
9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] derivatives of purines: a class of highly selective antiretroviral agents in vitro and in vivo. Jan Balzarini, Antonin Holy, J Jindrich, H Dvorakova, Z Hao, Robert Snoeck, Piet Herdewijn, D G Johns, Erik De Clercq Proceedings of the National Academy of Sciences of the United States of America 1991 pols set
A mutant of DNA polymerase I (Klenow fragment) with reduced fidelity. Steven S Carroll, M Cowart, Stephen J Benkovic Biochemistry 1991 pols set
DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies. Linda J Reha-Krantz, S Stocki, R L Nonay, E Dimayuga, L D Goodrich, William H Konigsberg, E K Spicer Proceedings of the National Academy of Sciences of the United States of America 1991 complete
Amplification of snap-back DNA synthesis reactions by the uvsX recombinase of bacteriophage T4. S W Morrical, M L Wong, B M Alberts The Journal of biological chemistry 1991 complete
Processing of DNA base damage by DNA polymerases. Dihydrothymine and beta-ureidoisobutyric acid as models for instructive and noninstructive lesions. Hiroshi Ide, L A Petrullo, Zafer Hatahet, Susan S Wallace The Journal of biological chemistry 1991 pols set
Saccharomyces cerevisiae replication factor C. II. Formation and activity of complexes with the proliferating cell nuclear antigen and with DNA polymerases delta and epsilon. Peter M J Burgers The Journal of biological chemistry 1991 new
Isolation of temperature-sensitive DNA polymerase III from Saccharomyces cerevisiae cdc2-2. A Blank, Lawrence A Loeb Biochemistry 1991 pols set
The genetic fate of molecularly cloned simian immunodeficiency virus in experimentally infected macaques. P R Johnson, T E Hamm, S Goldstein, S Kitov, V M Hirsch Virology 1991 new
Mutations within the RNase H domain of human immunodeficiency virus type 1 reverse transcriptase abolish virus infectivity. M Tisdale, T Schulze, Brendan A Larder, K Moelling The Journal of general virology 1991 pols set
DNA polymerase action blocked by adenine adducts induced by 5-hydroxymethylchrysene sulfate. Motoshi Suzuki, M Kojima, H Okuda, T Watabe, M Tada Biochem Int 1991 new
Aphidicolin, an inhibitor of DNA replication, blocks the TPA-induced differentiation of a human megakaryoblastic cell line, MEG-O1. Takashi Murate, T Hotta, K Tsushita, Motoshi Suzuki, T Yoshida, S Saga, H Saito, Shonen Yoshida Blood 1991 new
Cloning DPB3, the gene encoding the third subunit of DNA polymerase II of Saccharomyces cerevisiae. Hiroyuki Araki, Robert K Hamatake, A Morrison, A L Johnson, L H Johnston, Akio Sugino Nucleic acids research 1991 pols set
Human immunodeficiency virus reverse transcriptase. Effect of primer length on template-primer binding. J E Reardon, E S Furfine, N Cheng The Journal of biological chemistry 1991 pols set
Kelletinin I and kelletinin A from the marine mollusc Buccinulum corneum are inhibitors of eukaryotic DNA polymerase alpha. P Orlando, F Carretta, P Grippo, G Cimino, S De Stefano, G Strazzullo Experientia 1991 new
Purification and characterization of the 180- and 86-kilodalton subunits of the Saccharomyces cerevisiae DNA primase-DNA polymerase protein complex. The 180-kilodalton subunit has both DNA polymerase and 3'----5'-exonuclease activities. R G Brooke, R Singhal, David C Hinkle, L B Dumas The Journal of biological chemistry 1991 partial results
Rapid isolation of homogeneous cloned T7 gene 5 protein and T7 DNA polymerase by affinity chromatography on immobilized thioredoxin. I Slaby, A Holmgren Protein Expr Purif 1991 pols set
Partial purification and characterization of a beta-like DNA polymerase from Leishmania mexicana. L L Nolan, J H Rivera Biochem Int 1991 pols set
Cloning and overexpression of the gene encoding bacteriophage T5 DNA polymerase. D K Chatterjee, R K Fujimura, J H Campbell, G F Gerard Gene 1991 pols set
Immunoaffinity-purified DNA polymerase alpha from a mouse temperature-sensitive mutant, tsFT20 strain, is heat-labile. R Takada-Takayama, Fumio Hanaoka, Masami Yamada, M Ui The Journal of biological chemistry 1991 new
Accurate in vitro translesion synthesis by Escherichia coli DNA polymerase I (large fragment) on a site-specific, aminofluorene-modified oligonucleotide. M L Michaels, T M Reid, C M King, Louis J Romano Carcinogenesis 1991 pols set
Large fragment of DNA polymerase I from Bacillus stearothermophilus (Bst polymerase) is stable at ambient temperature. Y Y Lu, S Y Ye, G F Hong BioTechniques 1991 pols set
Inhibition of Escherichia coli DNA polymerase I catalysed DNA polymerization by trans-imidazolium-bisimidazoletetrachlororuthenate(III). E Holler, W Schaller, B Keppler Arzneimittelforschung 1991 pols set
Viral resistance to human immunodeficiency virus type 1-specific pyridinone reverse transcriptase inhibitors. J H Nunberg, W A Schleif, E J Boots, J A O'Brien, J C Quintero, J M Hoffman, E A Emini, M E Goldman Journal of virology 1991 pols set
DNA polymerase-mediated nucleotide incorporation adjacent to hydrocarbon-deoxyadenosine and hydrocarbon-deoxyguanosine adducts. A M Hruszkewycz, K A Canella, A Dipple Carcinogenesis 1991 new
Synthesis and anti-HIV activities of low molecular weight aurintricarboxylic acid fragments and related compounds. Mark Cushman, S Kanamathareddy, Erik De Clercq, Dominique Schols, M E Goldman, J A Bowen Journal of medicinal chemistry 1991 pols set
Direct radioactive labeling of unpurified PCR products using Klenow fragment. T K McDaniel, Y Huang, Jun Yin, S W Needleman, S J Meltzer BioTechniques 1991 pols set
Mechanisms of inhibitions of DNA polymerase gamma by nucleotide analogues having anti-HIV activities. Shunji Izuta, Mineo Saneyoshi, T Sakurai, Motoshi Suzuki, K Kojima, Shonen Yoshida Nucleic Acids Symp Ser 1991 new
Protein-DNA cross-linking demonstrates stepwise ATP-dependent assembly of T4 DNA polymerase and its accessory proteins on the primer-template. T L Capson, Stephen J Benkovic, Nancy G Nossal Cell 1991 complete
Compilation and alignment of DNA polymerase sequences. J Ito, D K Braithwaite Nucleic acids research 1991 new
Endothelin induces DNA polymerase alpha activity in ovaries of hypophysectomized estrogen-treated immature rats. S Usuki, S Otani, K Goto, H Matsumoto, Naomi Suzuki, M Yanagisawa, T Masaki Horm Metab Res 1991 new
Mouse DNA primase plays the principal role in determination of permissiveness for polyomavirus DNA replication. Toshihiko Eki, Takemi Enomoto, Chikahide Masutani, A Miyajima, R Takada, Y Murakami, T Ohno, Fumio Hanaoka, M Ui Journal of virology 1991 new
DNA synthesis on discontinuous templates by DNA polymerase I of Escherichia coli. J M Clark Gene 1991 pols set
Comparative inhibition of hepatitis B virus DNA polymerase and cellular DNA polymerases by triphosphates of sugar-modified 5-methyldeoxycytidines and of other nucleoside analogs. E Matthes, K Reimer, M von Janta-Lipinski, H Meisel, C Lehmann Antimicrob Agents Chemother 1991 new
A uv-sensitive Chinese hamster lung fibroblast cell line (V79/UC) with a possible defect in DNA polymerase activity is deficient in DNA repair. D M Creissen, C K Hill Radiat Res 1991 new
Characterization and mapping of the pyrophosphorolytic activity of the phage phi 29 DNA polymerase. Involvement of amino acid motifs highly conserved in alpha-like DNA polymerases. M A Blasco, Antonio Bernad, Luis Blanco, Margarita Salas The Journal of biological chemistry 1991 pols set
[RNA and DNA synthesis catalyzed by a DNA-polymerase alpha complex with primase from silkworm cells on single-stranded DNA]. V S Mikhaĭlov, S N Voronova, S B Akopov, P K Kuldyev, A M Atrazhev Mol Biol (Mosk) 1991 new
Effects of aging and dietary restriction on DNA polymerase expression in mice. Vinod K Srivastava, R D Tilley, S Miller, R Hart, D Busbee Exp Gerontol 1991 new
Interaction of simian virus 40 large T-antigen with cellular DNA polymerase alpha: studies with various T-antigen mutants of SV40. J M Pistillo, J K Vishwanatha Arch Virol 1991 new
Potent and selective inhibition of human immunodeficiency virus type 1 (HIV-1) by 5-ethyl-6-phenylthiouracil derivatives through their interaction with the HIV-1 reverse transcriptase. Masanori Baba, Erik De Clercq, Hiromichi Tanaka, M Ubasawa, H Takashima, K Sekiya, I Nitta, K Umezu, H Nakashima, S Mori Proceedings of the National Academy of Sciences of the United States of America 1991 pols set
Rat DNA sequence associated with a complex form of DNA polymerase alpha in nonregenerating liver interacts with a ubiquitous transcription/replication factor Oct-1. N A Timchenko, O P Zhuchenko, L T Timchenko, S M Iguchi-Ariga, H Ariga, V M Bozhkov, N V Tomilin Biomed Sci 1991 new
[The 3'----5'-exonucleases of rat liver enhance the fidelity of DNA synthesis catalyzed by mammalian DNA-polymerase alpha]. Igor V Shevelev, O K Legina, S N Naryzhnyĭ, F P Perrino, V M Krutiakov Dokl Akad Nauk SSSR 1991 new
Interaction of cis-diamminedichloroplatinum (II) with single-stranded DNA in the presence or absence of Escherichia coli single-stranded binding protein. Jean-Sébastien Hoffmann, Ulrich Hübscher, B Michot, Giuseppe Villani Biochemical pharmacology 1991 pols set
Three basic regions in adenovirus DNA polymerase interact differentially depending on the protein context to function as bipartite nuclear localization signals. L J Zhao, R Padmanabhan New Biol 1991 new
Measurement of the sequence specificity of covalent DNA modification by antineoplastic agents using Taq DNA polymerase. M Ponti, S M Forrow, R L Souhami, M D'Incalci, J A Hartley Nucleic acids research 1991 pols set
Structure and expression during development of Drosophila melanogaster gene for DNA polymerase alpha. Fumiko Hirose, Masamitsu Yamaguchi, Y Nishida, Mitsuko Masutani, Hiroshi Miyazawa, Fumio Hanaoka, Akio Matsukage Nucleic acids research 1991 new
Characterisation of the DNA-polymerase-alpha-primase complex from the silk glands of Bombyx mori. S Niranjanakumari, K P Gopinathan Eur J Biochem 1991 new
Stimulation of DNA polymerase alpha activity by microtubule-associated proteins. M Shioda, K Okuhara, H Murofushi, A Mori, H Sakai, K Murakami-Murofushi, Motoshi Suzuki, Shonen Yoshida Biochemistry 1991 new
The polymerase domain of Streptococcus pneumoniae DNA polymerase I. High expression, purification and characterization. M E Pons, A Díaz, S A Lacks, P López Eur J Biochem 1991 pols set
Selection of genetic variants of simian immunodeficiency virus in persistently infected rhesus monkeys. D P Burns, R C Desrosiers J Virol 1991 new
High level expression of DNA polymerases from herpesviruses. P F Ertl, M S Thomas, K L Powell The Journal of general virology 1991 pols set
5-Phosphoribosyl 1-pyrophosphate synthetase converts the acyclic nucleoside phosphonates 9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine and 9-(2-phosphonylmethoxyethyl)adenine directly to their antivirally active diphosphate derivatives. Jan Balzarini, Erik De Clercq The Journal of biological chemistry 1991 new
The 'A rule' of mutagen specificity: a consequence of DNA polymerase bypass of non-instructional lesions? B S Strauss Bioessays 1991 new
Bacillus subtilis DNA polymerase III: complete sequence, overexpression, and characterization of the polC gene. R A Hammond, Marjorie H Barnes, S L Mack, J A Mitchener, Neal C Brown Gene 1991 new
Identification and tryptic cleavage of the catalytic core of HeLa and calf thymus DNA polymerase epsilon. Tapio Kesti, Juhani E Syväoja The Journal of biological chemistry 1991 new
Accumulation of polycyclic aromatic hydrocarbon-induced single strand breaks is attributed to slower rejoining processes by DNA polymerase inhibitor, cytosine arabinoside in CHO-K1 cells. J K Park, J S Lee, H H Lee, I S Choi, S D Park Life Sci 1991 new
Mechanism of the sliding beta-clamp of DNA polymerase III holoenzyme. P T Stukenberg, P S Studwell-Vaughan, Mike E O'Donnell The Journal of biological chemistry 1991 pols set
Recombination hotspots in bacteriophage T4 are dependent on replication origins. W Y Yap, K N Kreuzer Proceedings of the National Academy of Sciences of the United States of America 1991 complete
[Affinity modification of DNA polymerase I from Escherichia coli and its Klenow fragment with nucleotide imidazolides]. S V Doronin, G A Nevinskiĭ, V V Khomov, Olga I Lavrik Mol Biol (Mosk) 1991 pols set
Intracellular metabolism and mechanism of anti-retrovirus action of 9-(2-phosphonylmethoxyethyl)adenine, a potent anti-human immunodeficiency virus compound. Jan Balzarini, Z Hao, Piet Herdewijn, D G Johns, Erik De Clercq Proceedings of the National Academy of Sciences of the United States of America 1991 new
Exonucleolytic proofreading of leading and lagging strand DNA replication errors. J D Roberts, D C Thomas, Thomas A Kunkel Proceedings of the National Academy of Sciences of the United States of America 1991 topics set
Ferrate oxidation of murine leukemia virus reverse transcriptase: identification of the template-primer binding domain. G Reddy, V B Nanduri, A Basu, Mukund J Modak Biochemistry 1991 new
Photoaffinity labeling of the primer binding domain in murine leukemia virus reverse transcriptase. R S Tirumalai, Mukund J Modak Biochemistry 1991 new
Influence of poly(ADP-ribose) polymerase on the enzymatic synthesis of SV40 DNA. Toshihiko Eki, Jerard Hurwitz The Journal of biological chemistry 1991 new
Steady state kinetics and inhibition of HIV-1 reverse transcriptase by a non-nucleoside dipyridodiazepinone, BI-RG-587, using a heteropolymeric template. E B Kopp, J J Miglietta, A G Shrutkowski, C K Shih, P M Grob, M T Skoog Nucleic acids research 1991 partial results
The primary structure of Plasmodium falciparum DNA polymerase delta is similar to drug sensitive delta-like viral DNA polymerases. B A Fox, D J Bzik Mol Biochem Parasitol 1991 pols set
Heteroduplex repair in extracts of human HeLa cells. D C Thomas, J D Roberts, Thomas A Kunkel The Journal of biological chemistry 1991 new
Kinetic interaction of human immunodeficiency virus type 1 reverse transcriptase with the antiviral tetrahydroimidazo[4,5,1-jk]-[1,4]-benzodiazepine-2-(1H)-thione compound, R82150. K B Frank, G J Noll, E V Connell, I S Sim The Journal of biological chemistry 1991 pols set
Stimulation of the processivity of the DNA polymerase of bacteriophage T4 by the polymerase accessory proteins. The role of ATP hydrolysis. Thale C Jarvis, J W Newport, Peter H von Hippel The Journal of biological chemistry 1991 complete
Decreased DNA polymerase sensitivity to 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in P388 murine leukemic cells resistant to vincristine. M Higashigawa, M Ido, Y Nagao, H Kuwabara, H Hori, T Ohkubo, H Kawasaki, M Sakurai Leuk Res 1991 new
Kinetics of extension of O6-methylguanine paired with cytosine or thymine in defined oligonucleotide sequences. M K Dosanjh, G Galeros, Myron F Goodman, B Singer Biochemistry 1991 pols set
Bst DNA polymerase permits rapid sequence analysis from nanogram amounts of template. D A Mead, J A McClary, J A Luckey, A J Kostichka, F R Witney, L M Smith BioTechniques 1991 pols set
Mammalian beta-polymerase promoter: phosphorylation of ATF/CRE-binding protein and regulation of DNA binding. E W Englander, S G Widen, Samuel H Wilson Nucleic acids research 1991 new
The DNA polymerase gene from the hyperthermophilic marine archaebacterium, Pyrococcus furiosus, shows sequence homology with alpha-like DNA polymerases. E J Mathur, M W Adams, W N Callen, J M Cline Nucleic acids research 1991 pols set
A general structure for DNA-dependent DNA polymerases. Luis Blanco, Antonio Bernad, M A Blasco, Margarita Salas Gene 1991 new
Fidelity of mammalian DNA replication and replicative DNA polymerases. D C Thomas, J D Roberts, R D Sabatino, T W Myers, Cheng-Keat Tan, Kathleen M Downey, Antero G So, Robert A Bambara, Thomas A Kunkel Biochemistry 1991 new
DNA footprinting studies of the complex formed by the T4 DNA polymerase holoenzyme at a primer-template junction. M M Munn, B M Alberts The Journal of biological chemistry 1991 complete
High-fidelity amplification using a thermostable DNA polymerase isolated from Pyrococcus furiosus. K S Lundberg, D D Shoemaker, M W Adams, J M Short, J A Sorge, E J Mathur Gene 1991 partial results
Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant. Smita S Patel, I Wong, Kenneth A Johnson Biochemistry 1991 partial results
Synthesis of DNA by DNA polymerase epsilon in vitro. Sang Hee Lee, Z Q Pan, A D Kwong, Peter M J Burgers, Jerard Hurwitz The Journal of biological chemistry 1991 complete Stu Linn
Protein-protein interactions of HIV-1 reverse transcriptase: implication of central and C-terminal regions in subunit binding. S P Becerra, A Kumar, M S Lewis, S G Widen, J Abbotts, E M Karawya, Stephen H Hughes, J Shiloach, Samuel H Wilson, M S Lewis Biochemistry 1991 pols set
Localization of a polynucleotide binding region in the HIV-1 reverse transcriptase: implications for primer binding. Robert W Sobol, R J Suhadolnik, A Kumar, B J Lee, D L Hatfield, Samuel H Wilson Biochemistry 1991 pols set
A leucine zipper-like motif may mediate HIV reverse transcriptase subunit binding. J G Baillon, N T Nashed, A Kumar, Samuel H Wilson, Donald M Jerina The New biologist 1991 pols set
Thermodynamics of A:G mismatch poly(dG) synthesis by human immunodeficiency virus 1 reverse transcriptase. J Abbotts, M Jaju, Samuel H Wilson The Journal of biological chemistry 1991 pols set
Mechanism of stimulation of DNA replication by bacteriophage phi 29 single-stranded DNA-binding protein p5. C Gutiérrez, G Martín, J M Sogo, Margarita Salas The Journal of biological chemistry 1991 new
Primary structure of the catalytic subunit of human DNA polymerase delta and chromosomal location of the gene. D W Chung, J A Zhang, Cheng-Keat Tan, E W Davie, Antero G So, Kathleen M Downey Proceedings of the National Academy of Sciences of the United States of America 1991 pols set
In vitro analysis of polychlorinated biphenyls (PCBs) and 2,3,4,7,8-pentachlorodibenzofuran (PCDF) cellular toxicity in PLC/PRF/5 cell proliferation--the effect of ursodeoxycholic acid, inchin-gorei-san and shou-saiko-to on cell toxicity. K Matsuoka, S Nonaka, T Ohgami, Hiromi Yoshida, F Murayama Fukuoka igaku zasshi = Hukuoka acta medica 1991 new
Subunit-selective mutagenesis indicates minimal polymerase activity in heterodimer-associated p51 HIV-1 reverse transcriptase. Stuart F J Le Grice, T Naas, B Wohlgensinger, O Schatz The EMBO journal 1991 pols set
MIP1 DNA polymerase of S. cerevisiae: structural similarity with the E. coli DNA polymerase I-type enzymes. Luis Blanco, Antonio Bernad, Margarita Salas Nucleic acids research 1991 new
Replication of the simian virus 40 chromosome with purified proteins. Y Ishimi, Kaoru Sugasawa, Fumio Hanaoka, A Kikuchi The Journal of biological chemistry 1991 new
Mutagenesis of conserved region I in the DNA polymerase from human adenovirus serotype 2. I Joung, M S Horwitz, J A Engler Virology 1991 new
Effects of T antigen and replication protein A on the initiation of DNA synthesis by DNA polymerase alpha-primase. K L Collins, T J Kelly Molecular and cellular biology 1991 new
DNA polymerase delta mediates increase in exchange production by X-radiation in human lymphocytes moving from G0 to G1. M A Bender, R C Moore Mutation research 1991 new
Sequencing with the large fragment of DNA polymerase I from Bacillus stearothermophilus. J McClary, S Y Ye, G F Hong, F Witney DNA Seq 1991 pols set
The protein-tyrosine kinase substrate, calpactin I heavy chain (p36), is part of the primer recognition protein complex that interacts with DNA polymerase alpha. H K Jindal, W G Chaney, C W Anderson, R G Davis, J K Vishwanatha The Journal of biological chemistry 1991 new
Purification of DNA polymerase delta as an essential simian virus 40 DNA replication factor. T Melendy, B Stillman The Journal of biological chemistry 1991 new
Inhibition of herpes simplex virus type 1 DNA polymerase by [1R(1 alpha,2 beta,3 alpha)]-9-[2,3-bis(hydroxymethyl)cyclobutyl] guanine. B J Terry, C W Cianci, M E Hagen Mol Pharmacol 1991 new
Drug binding to a DNA BZ molecule: analysis by chemical footprinting. Q Guo, M Lu, M Shahrestanifar, R D Sheardy, N R Kallenbach Biochemistry 1991 new
Deletion mutagenesis during polymerase chain reaction: dependence on DNA polymerase. N F Cariello, William G Thilly, James A Swenberg, T R Skopek Gene 1991 pols set
Characterization of human DNA polymerase delta and its immunochemical relationships with DNA polymerase alpha and epsilon. Marietta Y W T Lee, Y Q Jiang, S J Zhang, N L Toomey The Journal of biological chemistry 1991 pols set
Chromosomal behavior in starfish (Asterina pectinifera) zygotes under the effect of aphidicolin, an inhibitor of DNA polymerase. T Saiki, K Kyozuka, K Osanai, Y Hamaguchi Exp Cell Res 1991 new
Replication factors required for SV40 DNA replication in vitro. II. Switching of DNA polymerase alpha and delta during initiation of leading and lagging strand synthesis. Toshiki Tsurimoto, B Stillman The Journal of biological chemistry 1991 new
DNA polymerase delta mediates excision repair in growing cells damaged with ultraviolet radiation. D J Hunting, B J Gowans, S L Dresler Biochem Cell Biol 1991 new
SOS-inducible DNA polymerase II of E coli is homologous to replicative DNA polymerase of eukaryotes. Hideo Shinagawa, Hiroshi Iwasaki, Yoshizumi Ishino, A Nakata Biochimie 1991 new
Inactivation of DNA polymerase beta by in vitro phosphorylation with protein kinase C. T Tokui, M Inagaki, K Nishizawa, R Yatani, M Kusagawa, K Ajiro, Y Nishimoto, T Date, Akio Matsukage The Journal of biological chemistry 1991 new
Transcriptional organization of the Escherichia coli dnaX gene. A M Flower, Charles S McHenry Journal of molecular biology 1991 new
The implications of resistance to antiviral agents for herpesvirus drug targets and drug therapy. Donald M Coen Antiviral research 1991 new
Specificity and enzymatic mechanism of the editing exonuclease of Escherichia coli DNA polymerase III. S Brenowitz, S Kwack, Myron F Goodman, Mike E O'Donnell, H Echols The Journal of biological chemistry 1991 pols set
Mechanism of DNA replication fidelity for three mutants of DNA polymerase I: Klenow fragment KF(exo+), KF(polA5), and KF(exo-). B T Eger, Robert D Kuchta, Steven S Carroll, P A Benkovic, M E Dahlberg, Catherine M Joyce, Stephen J Benkovic Biochemistry 1991 topics set
Analysis of the HSV-1 strain 17 DNA polymerase gene reveals the expression of four different classes of pol transcripts. H Bludau, U K Freese Virology 1991 new
DNA polymerase B from wheat embryos: a plant delta-like DNA polymerase. M C Richard, Simon Litvak, Michel Castroviejo Arch Biochem Biophys 1991 new
The 5'-triphosphates of 3'-azido-3'-deoxythymidine and 2', 3'-dideoxynucleosides inhibit DNA polymerase gamma by different mechanisms. Shunji Izuta, Mineo Saneyoshi, T Sakurai, Motoshi Suzuki, K Kojima, Shonen Yoshida Biochem Biophys Res Commun 1991 new
Saccharomyces cerevisiae replication factor C. I. Purification and characterization of its ATPase activity. B L Yoder, Peter M J Burgers The Journal of biological chemistry 1991 new
DPB2, the gene encoding DNA polymerase II subunit B, is required for chromosome replication in Saccharomyces cerevisiae. Hiroyuki Araki, Robert K Hamatake, L H Johnston, Akio Sugino Proceedings of the National Academy of Sciences of the United States of America 1991 pols set
Expression of three cell proliferation-associated antigens, DNA polymerase alpha, Ki-67 antigen and transferrin receptor in nodal and cutaneous T-cell lymphomas. S Mitani, T Tango, Y Sonobe, N Baba, T Nagatani, S Nomoto, S Mori Int J Hematol 1991 new
Conformation of DNA-DNA polymerase I complex observed by scanning tunneling microscopy. C D Lu, M Q Li, M Y Qui, X W Yao, Y L Xu, M M Gu, J Hu J Biomol Struct Dyn 1991 pols set
DNA polymerase fidelity and the polymerase chain reaction. Kristin A Eckert, Thomas A Kunkel PCR Methods Appl 1991 topics set
HIV reverse transcriptase structure-function relationships. A Jacobo-Molina, Edward Arnold Biochemistry 1991 pols set
Changes in DNase and DNA-polymerase activities in different tissues of chick with age. E Suvarchala, C Ratnavathi, D R Prapurna, Kalluri Subba Rao Indian J Biochem Biophys 1991 new
Induction of DNA polymerase beta during proliferation of mitogen-stimulated human lymphocytes. Hiroshi Suzuki, M Menegazzi, A C De Prati, T Ogura, H Esumi, Akio Matsukage, M Libonati Biochem Biophys Res Commun 1991 new
DNA polymerase III holoenzyme. Components, structure, and mechanism of a true replicative complex. Charles S McHenry The Journal of biological chemistry 1991 new
[Amplification of the phage lambda DNA sequence by polymerase chain reaction using thermostable DNA polymerase]. A I Glukhov, M E Trofimova, S A Gordeev, T V Grebennikova, S V Vinogradov, V I Kiselev, V M Kramarov Mol Biol (Mosk) 1991 new
Chemotherapy of the acquired immune deficiency syndrome (AIDS): non-nucleoside inhibitors of the human immunodeficiency virus type 1 reverse transcriptase. Erik De Clercq International journal of immunopharmacology 1991 pols set
Psychotrine and its O-methyl ether are selective inhibitors of human immunodeficiency virus-1 reverse transcriptase. G T Tan, A D Kinghorn, Stephen H Hughes, J M Pezzuto The Journal of biological chemistry 1991 pols set
Human immunodeficiency virus reverse transcriptase T helper epitopes identified in mice and humans: correlation with a cytotoxic T cell epitope. A S De Groot, M Clerici, A Hosmalin, Stephen H Hughes, D Barnd, C W Hendrix, R Houghten, G M Shearer, J A Berzofsky The Journal of infectious diseases 1991 pols set
Identification and characterization of a 3' to 5' exonuclease associated with spinach chloroplast DNA polymerase. C A Keim, D W Mosbaugh Biochemistry 1991 new
Photolytic cleavage of DNA by nitrobenzamido ligands linked to 9-aminoacridines gives DNA polymerase substrates in a wavelength-dependent reaction. P E Nielsen, M Egholm, T Koch, J B Christensen, O Buchardt Bioconjug Chem 1991 new
Cell cycle-dependent phosphorylation of human DNA polymerase alpha. Heinz Peter Nasheuer, A Moore, A F Wahl, Teresa S-F Wang The Journal of biological chemistry 1991 pols set
Crystals of a ternary complex of human immunodeficiency virus type 1 reverse transcriptase with a monoclonal antibody Fab fragment and double-stranded DNA diffract x-rays to 3.5-A resolution. A Jacobo-Molina, Art D Clark, R L Williams, R G Nanni, Patrick K Clark, Andrea L Ferris, Stephen H Hughes, Edward Arnold Proceedings of the National Academy of Sciences of the United States of America 1991 new
Herpes simplex virus-specified DNA polymerase is the target for the antiviral action of 9-(2-phosphonylmethoxyethyl)adenine. S A Foster, J Cerny, Yung-Chi Cheng The Journal of biological chemistry 1991 new
Developmental expression of the embryonic chicken brain DNA polymerase alpha and its binding with monoclonal antibodies against human KB cell DNA polymerase alpha. S Ray, T J Kelley, S Campion, A P Seve, S Basu Cell Growth Differ 1991 new
Concatemer chain reaction: a Taq DNA polymerase-mediated mechanism for generating long tandemly repetitive DNA sequences. M J White, B W Fristensky, W F Thompson Anal Biochem 1991 pols set
Role of divalent cations in the 3',5'-exonuclease reaction of DNA polymerase I. H Han, J M Rifkind, A S Mildvan Biochemistry 1991 new
Studies on the activator 1 protein complex, an accessory factor for proliferating cell nuclear antigen-dependent DNA polymerase delta. Sang Hee Lee, A D Kwong, Z Q Pan, Jerard Hurwitz The Journal of biological chemistry 1991 new
Highly potent and selective inhibition of human immunodeficiency virus type 1 by a novel series of 6-substituted acyclouridine derivatives. Masanori Baba, Erik De Clercq, Hiromichi Tanaka, M Ubasawa, H Takashima, K Sekiya, I Nitta, K Umezu, R T Walker, S Mori Molecular pharmacology 1991 pols set
Cooperation of EBV DNA polymerase and EA-D(BMRF1) in vitro and colocalization in nuclei of infected cells. A Kiehl, D I Dorsky Virology 1991 pols set
[The effect of bases non-complementary to the template on the efficacy of primer interaction with the Klenow fragment of DNA polymerase I from Escherichia coli]. G A Nevinskiĭ, A V Nemudraia, A S Levina, I A Lokhova, V V Gorn, V V Khomov Mol Biol (Mosk) 1990 new
Does butylphenyl-deoxyguanosine triphosphate differentially inhibit DNA polymerase alpha and delta activities in permeabilized HeLa cells? D A Jackson Nucleic acids research 1990 new
High fidelity DNA synthesis by the Thermus aquaticus DNA polymerase. Kristin A Eckert, Thomas A Kunkel Nucleic acids research 1990 partial results
Aphidicolin inhibits DNA polymerase II of Escherichia coli, an alpha-like DNA polymerase. H Chen, C B Lawrence, S K Bryan, Robb E Moses Nucleic acids research 1990 pols set
Processive replication is contingent on the exonuclease subunit of DNA polymerase III holoenzyme. P S Studwell, Mike E O'Donnell The Journal of biological chemistry 1990 new
Expression of adenovirus type 2 DNA polymerase in insect cells infected with a recombinant baculovirus. C J Watson, R T Hay Nucleic acids research 1990 new
[Template-primer-dependent inactivation of DNA polymerase alpha from human placenta by 2',3'-epoxyadenosine-5'-triphosphate]. Vladimir N Podust, T O Korobeĭnicheva, G A Nevinskiĭ, V A Rikhter, T I Abramova, Olga I Lavrik Bioorg Khim 1990 new
Electrofocusing analysis of DNA polymerase beta in hypophysectomized rat testis. Akio Nagasaka, Shonen Yoshida, T Ohyama, R Masunaga, S Kato, Motoshi Suzuki, Mitsuyasu Itoh, T Kawabe Horm Metab Res 1990 new
Isolation of temperature-sensitive cell cycle mutants from mouse FM3A cells. Characterization of mutants with special reference to DNA replication. Toshihiko Eki, Takemi Enomoto, A Miyajima, Hiroshi Miyazawa, Y Murakami, Fumio Hanaoka, Masami Yamada, M Ui The Journal of biological chemistry 1990 new
Studies of the domain structure of mammalian DNA polymerase beta. Identification of a discrete template binding domain. A Kumar, S G Widen, K R Williams, Padmini Kedar, R L Karpel, Samuel H Wilson The Journal of biological chemistry 1990 pols set
Lysine-329 of murine leukemia virus reverse transcriptase: possible involvement in the template-primer binding function. V B Nanduri, Mukund J Modak Biochemistry 1990 new
The Escherichia coli polB gene, which encodes DNA polymerase II, is regulated by the SOS system. Hiroshi Iwasaki, A Nakata, Graham C Walker, Hideo Shinagawa J Bacteriol 1990 new
Purification of Thermus aquaticus DNA polymerase expressed in Escherichia coli. D R Engelke, A Krikos, M E Bruck, D Ginsburg Anal Biochem 1990 pols set
DNA polymerase activity of tomato fruit chromoplasts. E C Serra, N Carrillo FEBS letters 1990 new
Inhibition of herpes simplex virus DNA polymerase by diphosphates of acyclic phosphonylmethoxyalkyl nucleotide analogues. A Merta, I Votruba, I Rosenberg, M Otmar, H Hrebabecký, R Bernaerts, Antonín Holý Antiviral Res 1990 new
[Dependence of 3'-5-exonuclease activity of a fragment of Klenow DNA polymerase I from Escherichia coli on the length and structure of the cleaved oligonucleotide]. O V Khalabuda, G A Nevinskiĭ, A S Levina, V V Gorn, V V Khomov Mol Biol (Mosk) 1990 pols set
Effects of the bacteriophage T4 gene 41 and gene 32 proteins on RNA primer synthesis: coupling of leading- and lagging-strand DNA synthesis at a replication fork. T A Cha, B M Alberts Biochemistry 1990 complete
DNA polymerase II is encoded by the DNA damage-inducible dinA gene of Escherichia coli. C A Bonner, S Hays, K McEntee, Myron F Goodman Proceedings of the National Academy of Sciences of the United States of America 1990 pols set
Reduction of the potent DNA polymerase III holoenzyme 3'----5' exonuclease activity by template-primer analogues. Mark A Griep, J A Reems, M A Franden, Charles S McHenry Biochemistry 1990 pols set
DNA replication can overcome the silencer function on transcription. Masamitsu Yamaguchi, Akio Matsukage The New biologist 1990 new
Effect of DNA polymerase inhibitors on DNA repair in intact and permeable human fibroblasts: evidence that DNA polymerases delta and beta are involved in DNA repair synthesis induced by N-methyl-N'-nitro-N-nitrosoguanidine. R A Hammond, J K McClung, M R Miller Biochemistry 1990 new
DNA polymerase delta/PCNA: actions and interactions. M P Fairman J Cell Sci 1990 new
Herpes simplex virus type 1 DNA polymerase. Mechanism-based affinity chromatography. J E Reardon The Journal of biological chemistry 1990 new
Escherichia coli DNA polymerase I: inherent exonuclease activities differentiate between monofunctional and bifunctional adducts of DNA and cis- or trans-diamminedichloroplatinum(II). An exonuclease investigation of the kinetics of the adduct formation. F Bernges, G Dörner, Eggehard Holler Eur J Biochem 1990 pols set
Eukaryotic DNA replication. Enzymes and proteins acting at the fork. P Thömmes, Ulrich Hübscher European journal of biochemistry / FEBS 1990 new
Reverse transcriptases and genomic variability: the accuracy of DNA replication is enzyme specific and sequence dependent. M Ricchetti, H Buc The EMBO journal 1990 pols set
The requirement of IHF protein for extrachromosomal replication of the Escherichia coli oriC in a mutant deficient in DNA polymerase I activity. M Filutowicz, J Roll New Biol 1990 new
Targets and strategies for the antiviral chemotherapy of AIDS. Erik De Clercq Trends in pharmacological sciences 1990 pols set
Purification and characterization of a DNA polymerase from the archaebacterium Thermoplasma acidophilum. A Hamal, P Forterre, C Elie Eur J Biochem 1990 new
Potent DNA chain termination activity and selective inhibition of human immunodeficiency virus reverse transcriptase by 2',3'-dideoxyuridine-5'-triphosphate. Z Hao, D A Cooney, D Farquhar, CF Perno, K Zhang, R Masood, Y Wilson, N R Hartman, Jan Balzarini, D G Johns Molecular pharmacology 1990 pols set
Coprecipitation of 3'----5' exonuclease and DNA polymerase gamma with anti-DNA polymerase gamma antibody. Akio Matsukage, Y Nishimoto J Biochem 1990 new
Mechanism of HIV reverse transcriptase: enzyme-primer interaction as revealed through studies of a dNTP analogue, 3'-azido-dTTP. Padmini S Kedar, J Abbotts, T Kovács, K Lesiak, P Torrence, Samuel H Wilson Biochemistry 1990 pols set
[Interaction of dNTP-binding sites of human DNA polymerase alpha and The Klenow fragment of Escherichia coli DNA polymerase I with nucleotides, pyrophosphate and their analogs]. G A Nevinskiĭ, I A Potapova, N B Tarusova, O V Khalabuda, V V Khomov Mol Biol (Mosk) 1990 pols set
Deregulation of DNA polymerase beta by sense and antisense RNA expression in mouse 3T3 cells alters cell growth. B Z Zmudzka, Samuel H Wilson Somatic cell and molecular genetics 1990 new
Template primer-dependent binding of 5'-fluorosulfonyl-benzoyldeoxyadenosine by Escherichia coli DNA polymerase I. Identification of arginine 682 as the binding site and its implication in catalysis. V N Pandey, N A Kaushik, D S Pradhan, Mukund J Modak The Journal of biological chemistry 1990 pols set
Hydrolysis of 3'-terminal mispairs in vitro by the 3'----5' exonuclease of DNA polymerase delta permits subsequent extension by DNA polymerase alpha. Fred W Perrino, Lawrence A Loeb Biochemistry 1990 new
Effect of polyamines on the activity of malarial alpha-like DNA polymerase. U Bachrach, L Abu-Elheiga Eur J Biochem 1990 new
Identification of residues critical for the polymerase activity of the Klenow fragment of DNA polymerase I from Escherichia coli. A H Polesky, Thomas A Steitz, Nigel D F Grindley, Catherine M Joyce The Journal of biological chemistry 1990 partial results
DNA sequence analysis with a modified bacteriophage T7 DNA polymerase. Effect of pyrophosphorolysis and metal ions. Stanley Tabor, Charles C Richardson The Journal of biological chemistry 1990 pols set
Immunoaffinity purification and properties of Drosophila melanogaster DNA polymerase alpha-primase complex. Kazufumi Kuroda, R Kagiyama-Takahashi, T Shinomiya J Biochem 1990 new
DNA polymerase delta: a second eukaryotic DNA replicase. Kathleen M Downey, Cheng-Keat Tan, Antero G So Bioessays 1990 new
Molecular cloning, structure and expression of the yeast proliferating cell nuclear antigen gene. G A Bauer, Peter M J Burgers Nucleic acids research 1990 new
Sequencing of Saccharomyces telomeres cloned using T4 DNA polymerase reveals two domains. S S Wang, V A Zakian Molecular and cellular biology 1990 pols set
Protein-protein interactions between adenovirus DNA polymerase and nuclear factor I mediate formation of the DNA replication preinitiation complex. M Chen, N Mermod, M S Horwitz The Journal of biological chemistry 1990 new
Characterization of the 5' to 3' exonuclease associated with Thermus aquaticus DNA polymerase. Matthew J Longley, S E Bennett, D W Mosbaugh Nucleic acids research 1990 new
Animal cell DNA polymerases in DNA repair. Fred W Perrino, Lawrence A Loeb Mutation research 1990 new
The DNA polymerase from the archaebacterium Sulfolobus acidocaldarius: a thermophilic and thermoresistant enzyme which can perform automated polymerase chain reaction. S Salhi, C Elie, O Jean-Jean, M Meunier-Rotival, P Forterre, J M Rossignol, A M de Recondo Biochem Biophys Res Commun 1990 new
Single-stranded-DNA-dependent ATPase from HeLa cells that stimulates DNA polymerase alpha-primase activity: purification and characterization of the ATPase. J K Vishwanatha, E F Baril Biochemistry 1990 new
Identification and properties of the catalytic domain of mammalian DNA polymerase beta. A Kumar, J Abbotts, E M Karawya, Samuel H Wilson Biochemistry 1990 pols set
Transcriptional mapping of a DNA replication gene cluster in bacteriophage T4. Sites for initiation, termination, and mRNA processing. Tien Hsu, Jim D Karam The Journal of biological chemistry 1990 complete
A comparison of the initiating abilities of ribo- and deoxyriboprimers in DNA polymerization catalyzed by AMV reverse transcriptase. I A Lokhova, G A Nevinsky, V V Gorn, A G Veniaminova, M V Repkova, V M Kavsan, N K Rudenko, Olga I Lavrik FEBS letters 1990 new
Base mispair extension kinetics. Comparison of DNA polymerase alpha and reverse transcriptase. L V Mendelman, John Petruska, Myron F Goodman The Journal of biological chemistry 1990 new
Inhibition by AZT of HIV-1 replication in acutely infected U-937 cells. F Boulerice, Mark A. Wainberg Journal of leukocyte biology 1990 pols set
Holoenzyme DNA polymerase III fixes mutations. S K Bryan, M Hagensee, Robb E Moses Mutation research 1990 new
Purification and some properties of a thermostable DNA polymerase from a Thermotoga species. H D Simpson, T Coolbear, M Vermue, R M Daniel Biochem Cell Biol 1990 new
Dissociation of the DNA polymerase III holoenzyme beta 2 subunits is accompanied by conformational change at distal cysteines 333. Mark A Griep, Charles S McHenry The Journal of biological chemistry 1990 new
Isolation and characterization of herpes simplex virus mutants containing engineered mutations at the DNA polymerase locus. A I Marcy, D R Yager, Donald M Coen Journal of virology 1990 new
Autogenous translational operator recognized by bacteriophage T4 DNA polymerase. C Tuerk, S Eddy, D Parma, L Gold Journal of molecular biology 1990 topics set
Inhibition of DNA excision by DNA polymerase-alpha inhibitor in UV-damaged HeLa cells. C O Joe, M A Lee, B S Choi, K W Kang Toxicol Lett 1990 new
Amplification of DNA sequences of Epstein-Barr and human immunodeficiency viruses using DNA-polymerase from Thermus thermophilus. A I Glukhov, S A Gordeev, S V Vinogradov, V I Kiselev, V M Kramarov, O I Kiselev, E S Severin Mol Cell Probes 1990 new
A third essential DNA polymerase in S. cerevisiae. A Morrison, Hiroyuki Araki, Alan B Clark, Robert K Hamatake, Akio Sugino Cell 1990 new
Translational regulation of herpes simplex virus DNA polymerase. D R Yager, A I Marcy, Donald M Coen J Virol 1990 new
Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme. Robert K Hamatake, H Hasegawa, Alan B Clark, Katarzyna Bebenek, Thomas A Kunkel, Akio Sugino The Journal of biological chemistry 1990 partial results
Purification of a thermostable DNA polymerase from Thermus thermophilus HB8, useful in the polymerase chain reaction. N Carballeira, M Nazabal, J Brito, O Garcia BioTechniques 1990 new
Functional domain for priming activity in the phage phi 29 terminal protein. C Garmendia, José M Hermoso, Margarita Salas Gene 1990 pols set
Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of G.T mispairs in nuclear extracts from human cells. K Wiebauer, J Jiricny Proceedings of the National Academy of Sciences of the United States of America 1990 new
Protein binding elements in the human beta-polymerase promoter. E W Englander, Samuel H Wilson Nucleic acids research 1990 pols set
Effect of enhanced synthesis of the epsilon subunit of DNA polymerase III on spontaneous and UV-induced mutagenesis of the Escherichia coli glyU gene. Z Ciesla, Piotr Jonczyk, I Fijalkowska Mol Gen Genet 1990 new
[Clinical significance of HBV-associated DNA polymerase assay]. K Mitamura Nippon Rinsho 1990 new
cis-syn thymine dimers are not absolute blocks to replication by DNA polymerase I of Escherichia coli in vitro. John-Stephen Taylor, C L O'Day Biochemistry 1990 pols set
Site-directed mutagenesis of the YCDTDS amino acid motif of the phi 29 DNA polymerase. Antonio Bernad, Luis Blanco, Margarita Salas Gene 1990 pols set
Interactions between SV40 T antigen and DNA polymerase alpha. J V Gannon, D P Lane New Biol 1990 new
The highly conserved amino acid sequence motif Tyr-Gly-Asp-Thr-Asp-Ser in alpha-like DNA polymerases is required by phage phi 29 DNA polymerase for protein-primed initiation and polymerization. Antonio Bernad, José María Lázaro, Margarita Salas, Luis Blanco Proceedings of the National Academy of Sciences of the United States of America 1990 pols set
Effect of nonviable preparations from human immunodeficiency virus type 1 on nuclear matrix-associated DNA polymerase alpha and DNA topoisomerase II activities. W E Müller, E Matthes, P Reuter, R Wenger, K Friese, Y Kuchino, H C Schröder J Acquir Immune Defic Syndr 1990 new
Structure of DNA polymerase alpha-primase complexes from mammalian cells analyzed by using monoclonal antibodies. T Kozu, K Nikaido, T Yagura J Biochem 1990 pols set
Inhibition of hepatitis B virus DNA polymerase by 3'-fluorothymidine triphosphate and other modified nucleoside triphosphate analogs. H Meisel, K Reimer, M von Janta-Lipinski, D Bärwolff, E Matthes J Med Virol 1990 new
The private life of DNA polymerase I. Arthur Kornberg Methods in enzymology 1990 new
The effect of DNA polymerase inhibitors on the cytotoxicity of cisplatin in human ovarian carcinoma cells. E J Katz, P A Andrews, S B Howell Cancer Commun 1990 new
Further biochemical characterization of wheat DNA primase: possible functional implication of copurification with DNA polymerase A. Patricia Laquel, Michel Castroviejo, Simon Litvak Nucleic acids research 1990 new
Substrate specificity of the exonuclease associated with calf DNA polymerase. R D Sabatino, T W Myers, Robert A Bambara Cancer research 1990 new
Role of DNA polymerase 3'----5' exonuclease activity in the bypass of aminofluorene lesions in DNA. B S Strauss, Jianhong Wang Carcinogenesis 1990 pols set
Structure-function relationships in Escherichia coli promoter DNA. M S Horwitz, Lawrence A Loeb Prog Nucleic Acid Res Mol Biol 1990 new
Prevalence and heterogeneity of serum DNA polymerase activity in patients with non-A, non-B hepatitis and HBsAg-negative blood donors with elevated SGPT. Satoshi Watanabe, U Kano, T Ito, R Kakehashi, J Ikoma, T Murata, S Suzuki Hepatogastroenterology 1990 new
Structure-function analysis of mononucleotides and short oligonucleotides in the priming of enzymatic DNA synthesis. G A Nevinsky, A G Veniaminova, A S Levina, Vladimir N Podust, Olga I Lavrik, Eggehard Holler Biochemistry 1990 pols set
Transfected human beta-polymerase promoter contains a ras-responsive element. Padmini S Kedar, D R Lowy, S G Widen, Samuel H Wilson Molecular and cellular biology 1990 new
Development of novel inhibitor probes of DNA polymerase III based on dGTP analogs of the HPUra type: base, nucleoside and nucleotide derivatives of N2-(3,4-dichlorobenzyl)guanine. Michelle M Butler, L W Dudycz, N N Khan, George E Wright, Neal C Brown Nucleic acids research 1990 new
On the DNA polymerase-a mutant: immunofluorescence assay of UV-induced thymidine dimers in Aphr-4-2 cells. P K Liu, G S Hsu Somat Cell Mol Genet 1990 new
Infection of human thymic lymphocytes by HIV-1. M Tremblay, K Numazaki, H Goldman, Mark A. Wainberg Journal of acquired immune deficiency syndromes 1990 pols set
A monoclonal antibody that neutralizes Epstein-Barr virus DNA polymerase activity. C H Tsai, M V Williams, R Glaser Intervirology 1990 new
Site-specific mutagenesis of PRD1 DNA polymerase: mutations in highly conserved regions of the family B DNA polymerase. G H Jung, M C Leavitt, M Schultz, J Ito Biochem Biophys Res Commun 1990 new
Purification and properties of a thermophilic and thermostable DNA polymerase from the archaebacterium Sulfolobus solfataricus. R Rella, C A Raia, Francesca M Pisani, S D'Auria, R Nucci, A Gambacorta, M De Rosa, Mosè Rossi Ital J Biochem 1990 new
Identification and fine structure of proliferating hepatocytes in malignant and nonmalignant liver diseases by use of a monoclonal antibody against DNA polymerase alpha. S Seki, H Sakaguchi, N Kawakita, A Yanai, K Kim, Y Mizoguchi, Kazuki Kobayashi Hum Pathol 1990 new
A low molecular weight DNA polymerase from wheat embryos. Michel Castroviejo, M T Gatius, Simon Litvak Plant Mol Biol 1990 new
Structure-function studies of the herpes simplex virus type 1 DNA polymerase. M L Haffey, J Novotny, R E Bruccoleri, R D Carroll, J T Stevens, J T Matthews J Virol 1990 new
Functions of replication factor C and proliferating-cell nuclear antigen: functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T4. Toshiki Tsurimoto, B Stillman Proceedings of the National Academy of Sciences of the United States of America 1990 new
Studies on the initiation and elongation reactions in the simian virus 40 DNA replication system. T Matsumoto, Toshihiko Eki, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1990 pols set
Translation of hepatitis B virus DNA polymerase from the internal AUG codon, not from the upstream AUG codon for the core protein. S Kawamoto, S Yamamoto, K Ueda, T Nagahata, O Chisaka, Kiminori Matsubara Biochem Biophys Res Commun 1990 new
Purification of a thermostable DNA polymerase from a Thermotoga species. H D Simpson, T Coolbear, R M Daniel Ann N Y Acad Sci 1990 new
Immunohistochemical demonstration of DNA polymerase alpha in human brain-tumor cells. K Kunishio, N Mishima, T Matsuhisa, K Tsuno, N Matsumi, T Satoh, K Matsumoto, T Furuta, A Nishimoto, T Shiraishi J Neurosurg 1990 new
High frequency of isolation of defective human immunodeficiency virus type 1 and heterogeneity of viral gene expression in clones of infected U-937 cells. F Boulerice, S Bour, R Geleziunas, A Lvovich, Mark A. Wainberg Journal of virology 1990 new
Purification and characterization of mouse DNA polymerase alpha devoid of primase activity. R Takada-Takayama, Motoshi Suzuki, Takemi Enomoto, Fumio Hanaoka, M Ui FEBS letters 1990 new
Interactions between the adenovirus type 2 DNA polymerase and the DNA binding domain of nuclear factor I. J Bosher, E C Robinson, R T Hay New Biol 1990 new
Plasmodium falciparum: properties of an alpha-like DNA polymerase, the key enzyme in DNA synthesis. L Abu-Elheiga, D T Spira, U Bachrach Exp Parasitol 1990 new
DNA polymerases alpha, delta, and epsilon: three distinct enzymes from HeLa cells. J Syväoja, S Suomensaari, C Nishida, J S Goldsmith, G S Chui, S Jain, Stuart Linn Proceedings of the National Academy of Sciences of the United States of America 1990 new
Inactivation of DNA polymerase by adenosine 2',3'-riboepoxide 5'-triphosphate allows estimation of the primers affinity. Vladimir N Podust, T O Korobeinicheva, G A Nevinsky, A S Levina, Olga I Lavrik Molecular biology reports 1990 pols set
Two forms of DNA polymerase delta from mouse cells. Purification and properties. Mehran Goulian, S M Herrmann, J W Sackett, S L Grimm The Journal of biological chemistry 1990 partial results
DNA primase stimulatory factor from mouse FM3A cells has an RNase H activity. Purification of the factor and analysis of the stimulation. Chikahide Masutani, Takemi Enomoto, Motoshi Suzuki, Fumio Hanaoka, M Ui The Journal of biological chemistry 1990 new
The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I. Katarzyna Bebenek, Catherine M Joyce, M P Fitzgerald, Thomas A Kunkel The Journal of biological chemistry 1990 complete
Analysis by DNA polymerase alpha activity of human breast tumour proliferation and the effect of endocrine therapy. N G Coldham, L C Lai, M J Reed, M W Ghilchik, N A Shaikh, V H James Br J Cancer 1990 new
Mapping of the gene for DNA polymerase beta to mouse chromosome 8. O W McBride, C A Kozak, Samuel H Wilson Cytogenetics and cell genetics 1990 new
The gamma subunit of DNA polymerase III holoenzyme of Escherichia coli is produced by ribosomal frameshifting. A M Flower, Charles S McHenry Proceedings of the National Academy of Sciences of the United States of America 1990 pols set
Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: deletions and deletions with insertions. Vinay K Pathak, H M Temin Proceedings of the National Academy of Sciences of the United States of America 1990 new
Human immunodeficiency virus reverse transcriptase. Substrate and inhibitor kinetics with thymidine 5'-triphosphate and 3'-azido-3'-deoxythymidine 5'-triphosphate. J E Reardon, W H Miller The Journal of biological chemistry 1990 partial results
Comparison of exonucleolytic activities of herpes simplex virus type-1 DNA polymerase and DNase. Charles W Knopf, Klaus Weisshart Eur J Biochem 1990 new
Purification and characterization of a DNA polymerase from the cyanobacterium Anacystis nidulans R2. H J Lin, G C Cannon, S Heinhorst Nucleic acids research 1990 new
DNA helicase from calf thymus. Purification to apparent homogeneity and biochemical characterization of the enzyme. P Thömmes, Ulrich Hübscher The Journal of biological chemistry 1990 new
DNA polymerase alpha. An immunohistochemical marker for proliferating cells in normal and neoplastic human tissues. Y Tsutsumi, S Hori, N Onoda Am J Clin Pathol 1990 pols set
Functional interaction between the herpes simplex-1 DNA polymerase and UL42 protein. T R Hernandez, I. Robert Lehman The Journal of biological chemistry 1990 new
Interaction of Escherichia coli DNA polymerase I with azidoDNA and fluorescent DNA probes: identification of protein-DNA contacts. C E Catalano, D J Allen, Stephen J Benkovic Biochemistry 1990 pols set
Effect of divalent and monovalent cations on calf thymus PCNA-independent DNA polymerase delta and its 3'----5' exonuclease. Federico Focher, A Verri, Giovanni Maga, Silvio Spadari, Ulrich Hübscher FEBS letters 1990 new
Interaction of dNTP, pyrophosphate and their analogs with the dNTP-binding sites of E. coli DNA polymerase I Klenow fragment and human DNA polymerase alpha. I A Potapova, G A Nevinsky, A G Veniaminova, V V Khomov, Olga I Lavrik FEBS letters 1990 topics set
NMR studies of the active site of DNA polymerase I and of a 50-residue peptide fragment of the enzyme. Gregory P Mullen, J B Vaughn, P Shenbagamurthi, A S Mildvan Biochem Pharmacol 1990 new
SV40 T antigen binds directly to the large subunit of purified DNA polymerase alpha. I Dornreiter, A Höss, A K Arthur, Ellen Fanning The EMBO journal 1990 new
Mechanism of action of 5-(2-chloroethyl)-2'-deoxyuridine, a selective inhibitor of herpes simplex virus replication. Erik De Clercq, R Bernaerts, A Merta, Brigitte Rosenwirth Molecular pharmacology 1990 new
Excision repair of UV-damaged plasmid DNA in Xenopus oocytes is mediated by DNA polymerase alpha (and/or delta). J K Saxena, J B Hays, E J Ackerman Nucleic acids research 1990 new
Engineered herpes simplex virus DNA polymerase point mutants: the most highly conserved region shared among alpha-like DNA polymerases is involved in substrate recognition. A I Marcy, Charles B C Hwang, K L Ruffner, Donald M Coen J Virol 1990 new
Selective virus inhibitors. Erik De Clercq Microbiologica 1990 pols set
A novel functional domain of an alpha-like DNA polymerase. The binding site on the herpes simplex virus polymerase for the viral UL42 protein. P Digard, Donald M Coen The Journal of biological chemistry 1990 new
[Methods of DNA sequencing with Taq DNA polymerase]. Yoshizumi Ishino, Kiyozo Asada Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1990 pols set
Enzymatic activities of overexpressed herpes simplex virus DNA polymerase purified from recombinant baculovirus-infected insect cells. A I Marcy, P D Olivo, M D Challberg, Donald M Coen Nucleic acids research 1990 new
Susceptibilities of zidovudine-susceptible and -resistant human immunodeficiency virus isolates to antiviral agents determined by using a quantitative plaque reduction assay. Brendan A Larder, B Chesebro, Douglas D Richman Antimicrob Agents Chemother 1990 topics set
Modulation by polyamines of DNA-dependent DNA polymerase activity from human serum. S Shimamura, H Hibasami, U Kano, Satoshi Watanabe, S Suzuki, K Nakashima Int J Biochem 1990 new
An attempt to unify the structure of polymerases. M Delarue, O Poch, N Tordo, D Moras, P Argos Protein Eng 1990 new
Frameshift errors initiated by nucleotide misincorporation. Katarzyna Bebenek, Thomas A Kunkel Proceedings of the National Academy of Sciences of the United States of America 1990 new
Inactivation of human immunodeficiency virus type 1 in tissue culture fluid and in genital secretions by the spermicide benzalkonium chloride. Mark A. Wainberg, Bonnie Spira, G Bleau, R Thomas Journal of clinical microbiology 1990 pols set
Revised nomenclature for eukaryotic DNA polymerases. Peter M J Burgers, Robert A Bambara, Judith L Campbell, L M Chang, Kathleen M Downey, Ulrich Hübscher, Marietta Y W T Lee, Stuart Linn, Antero G So, Silvio Spadari Eur J Biochem 1990 pols set
Evolving mutation rates and prospects for antimutagenesis Mechanisms of Environmental Mutagenesis-Carcinogenesis 1990 topics set
Mechanism of elongation of primed DNA by DNA polymerase delta, proliferating cell nuclear antigen, and activator 1. Sang Hee Lee, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1990 new
Translational frameshifting generates the gamma subunit of DNA polymerase III holoenzyme. Z Tsuchihashi, Arthur Kornberg Proceedings of the National Academy of Sciences of the United States of America 1990 pols set
Characterization of reverse transcriptase activity and susceptibility to other nucleosides of AZT-resistant variants of HIV-1. Results from the Canadian AZT Multicentre Study. Mark A. Wainberg, M Tremblay, R Rooke, N Blain, H Soudeyns, Michael A. Parniak, X J Yao, X G Li, M Fanning, Julio S G Montaner Annals of the New York Academy of Sciences 1990 new
Selective inhibition of DNA primase activity associated with DNA polymerase alpha from calf thymus. J B Bodner, Robert A Bambara Cancer Biochem Biophys 1990 new
Potent inhibitory effects of the 5'-triphosphates of (E)-5-(2-bromovinyl)-2'-deoxyuridine and (E)-5-(2-bromovinyl)-1-beta-D-arabinofuranosyluracil on DNA polymerase gamma. K Ono, H Nakane, Erik De Clercq Eur J Biochem 1990 new
Inhibition of avian myeloblastosis virus reverse transcriptase by aurochloric acid. M Semba, N Tanaka, Masami Yamada, F Takeuchi, K Matsuta, T Miyamoto, Fumio Hanaoka, M Ui Japanese journal of cancer research : Gann 1990 new
Inhibition of HIV-1 replication by a nonnucleoside reverse transcriptase inhibitor. V J Merluzzi, K D Hargrave, M Labadia, K Grozinger, M Skoog, J C Wu, C K Shih, K Eckner, S Hattox, J Adams Science 1990 pols set
Fidelity of animal cell DNA polymerases alpha and delta and of a human DNA replication complex. D C Thomas, J D Roberts, M P Fitzgerald, Thomas A Kunkel Basic life sciences 1990 new
DNA polymerase epsilon: the latest member in the family of mammalian DNA polymerases. Juhani E Syväoja Bioessays 1990 pols set
Total reconstitution of DNA polymerase III holoenzyme reveals dual accessory protein clamps. Mike E O'Donnell, P S Studwell The Journal of biological chemistry 1990 new
Immunologic and proteolytic analysis of HIV-1 reverse transcriptase structure. Andrea L Ferris, A Hizi, S D Showalter, S Pichuantes, L Babe, C S Craik, Stephen H Hughes Virology 1990 pols set
Mutational analysis of the ribonuclease H activity of human immunodeficiency virus 1 reverse transcriptase. A Hizi, Stephen H Hughes, M Shaharabany Virology 1990 pols set
DNA polymerase alpha does not mediate G0-G1 increase in yield of X-ray-induced exchange aberrations in human peripheral blood lymphocytes. M A Bender, R C Moore Mutation research 1990 new
Activity profiles of enzymes that control the uracil incorporation into DNA during neuronal development. Federico Focher, P Mazzarello, A Verri, Ulrich Hübscher, Silvio Spadari Mutation research 1990 new
Fidelity of DNA polymerase alpha partially purified from a mutator mutant and wild-type mouse FM3A cells. M Hyodo, K Suzuki Tokai J Exp Clin Med 1990 new
DNA polymerase I and a protein complex bind specifically to E. coli palindromic unit highly repetitive DNA: implications for bacterial chromosome organization. E Gilson, D Perrin, M Hofnung Nucleic acids research 1990 new
Structural and functional analysis of temperature-sensitive mutants of the phage phi 29 DNA polymerase. M A Blasco, Luis Blanco, E Parés, Margarita Salas, Antonio Bernad Nucleic acids research 1990 pols set
AZT (zidovudine) may act postintegrationally to inhibit generation of HIV-1 progeny virus in chronically infected cells. R Rooke, M Tremblay, Mark A. Wainberg Virology 1990 pols set
Site-directed mutagenesis of recombinant rat DNA polymerase beta: involvement of arginine-183 in primer recognition. T Date, S Yamamoto, K Tanihara, Y Nishimoto, N Liu, Akio Matsukage Biochemistry 1990 new
Temperature-dependent association of DNA polymerase alpha activity with the nuclear matrix. A M Martelli, R S Gilmour, E Falcieri, F A Manzoli, L Cocco Exp Cell Res 1990 new
Cloning of PCR products after defined cohesive termini are created with T4 DNA polymerase. A W Stoker Nucleic acids research 1990 pols set
In vitro replication through nucleosomes without histone displacement. C Bonne-Andrea, M L Wong, B M Alberts Nature 1990 complete
Purification and characterization of the RNase H domain of HIV-1 reverse transcriptase expressed in recombinant Escherichia coli. S P Becerra, G M Clore, A M Gronenborn, A R Karlström, S J Stahl, Samuel H Wilson, P T Wingfield FEBS letters 1990 pols set
DNA polymerase alpha-primase complexes from carcinogen-treated Chinese hamster ovary cells. A Brucker, Lawrence A Loeb, H W Thielmann Cancer research 1990 new
Striking similarity of the distribution patterns of the poly(ADP-ribose) polymerase and DNA polymerase beta among various mouse organs. T Ogura, N Takenouchi, Masamitsu Yamaguchi, Akio Matsukage, T Sugimura, H Esumi Biochem Biophys Res Commun 1990 new
Comparative efficiency of forming m4T.G versus m4T.A base pairs at a unique site by use of Escherichia coli DNA polymerase I (Klenow fragment) and Drosophila melanogaster polymerase alpha-primase complex. M K Dosanjh, John M Essigmann, Myron F Goodman, B Singer Biochemistry 1990 pols set
A self-splicing group I intron in the DNA polymerase gene of Bacillus subtilis bacteriophage SPO1. H Goodrich-Blair, V Scarlato, J M Gott, M Q Xu, D A Shub Cell 1990 pols set
DNA polymerase action on bulky deoxyguanosine and deoxyadenosine adducts. D B Reardon, C A Bigger, A Dipple Carcinogenesis 1990 pols set
Utilization of 2',3'-dideoxyguanosine 5'-triphosphate as an inhibitor and substrate for DNA polymerase alpha. K Ono, H Nakane Biomed Pharmacother 1990 new
Mutations produced by DNA polymerase III holoenzyme of Escherichia coli after in vitro synthesis in the absence of single-strand binding protein. M Carraway, C Rewinski, M G Marinus Molecular microbiology 1990 pols set
Rat DNA polymerase beta gene can join in excision repair of Escherichia coli. T Ohnishi, S Yuba, T Date, H Utsumi, Akio Matsukage Nucleic acids research 1990 pols set
Inactivation of DNA polymerase 1, alpha-amylase and protease by basic dyes and inhibition of microbial growth. T Ogawa, I Yoshinori, C Yatome Bull Environ Contam Toxicol 1990 new
Purification of DNA polymerase II stimulatory factor I, a yeast single-stranded DNA-binding protein. W C Brown, J K Smiley, Judith L Campbell Proceedings of the National Academy of Sciences of the United States of America 1990 new
Murine DNA polymerase alpha fills gaps to completion in a direct assay. Altered kinetics of de novo DNA synthesis at single nucleotide gaps. S K Davey, E A Faust The Journal of biological chemistry 1990 new
Release of RNA polymerase from vero cell mitochondria after herpes simplex virus type 1 infection. T Tsurumi, I. Robert Lehman Journal of virology 1990 new
Changes in the DNA polymerase beta gene expression during development of lung, brain, and testis suggest an involvement of the enzyme in DNA recombination. Radosława Nowak, M Woszczynski, Janusz A Siedlecki Exp Cell Res 1990 new
Metal binding to DNA polymerase I, its large fragment, and two 3',5'-exonuclease mutants of the large fragment. Gregory P Mullen, E H Serpersu, L J Ferrin, Lawrence A Loeb, A S Mildvan The Journal of biological chemistry 1990 new
Casein kinase II phosphorylates DNA-polymerase-alpha--DNA-primase without affecting its basic enzymic properties. V Podust, G Bialek, H Sternbach, Frank Grosse Eur J Biochem 1990 new
"Macromolecular crowding": thermodynamic consequences for protein-protein interactions within the T4 DNA replication complex. Thale C Jarvis, D M Ring, S S Daube, Peter H von Hippel The Journal of biological chemistry 1990 complete
Rapid purification of homodimer and heterodimer HIV-1 reverse transcriptase by metal chelate affinity chromatography. Stuart F J Le Grice, F Grüninger-Leitch Eur J Biochem 1990 new
The UvsY protein of bacteriophage T4 modulates recombination-dependent DNA synthesis in vitro. S W Morrical, B M Alberts The Journal of biological chemistry 1990 complete
Properties of overexpressed phage T5 D15 exonuclease. Similarities with Escherichia coli DNA polymerase I 5'-3' exonuclease. J R Sayers, F Eckstein The Journal of biological chemistry 1990 pols set
Peptide mapping of the four subunits of the mouse DNA polymerase alpha-primase complex. R Takada-Takayama, S Tada, Fumio Hanaoka, M Ui Biochemical and biophysical research communications 1990 new
Photoaffinity labeling of the Klenow fragment with 8-azido-dATP. J Rush, William H Konigsberg The Journal of biological chemistry 1990 pols set
Analysis of cytokine mRNA and DNA: detection and quantitation by competitive polymerase chain reaction. G Gilliland, S Perrin, K Blanchard, H F Bunn Proceedings of the National Academy of Sciences of the United States of America 1990 new
Characterization of eukaryotic DNA polymerases: aphidicolin resistant mutants of Neurospora with altered DNA polymerase. N C Mishra, A Almasan, M Cooley Prog Clin Biol Res 1990 new
Localization of the herpes simplex virus type 1 65-kilodalton DNA-binding protein and DNA polymerase in the presence and absence of viral DNA synthesis. L D Goodrich, P A Schaffer, D I Dorsky, C S Crumpacker, Deborah S Parris J Virol 1990 new
Synthesis of DNA by human immunodeficiency virus reverse transcriptase is preferentially blocked at template oligo(deoxyadenosine) tracts. K J Williams, Lawrence A Loeb, M Fry The Journal of biological chemistry 1990 pols set
HIV-1 reverse transcriptase: structure predictions for the polymerase domain. A M Barber, A Hizi, J V Maizel, Stephen H Hughes AIDS research and human retroviruses 1990 pols set
NaF and mononucleotides as inhibitors of 3'-5'-exonuclease activity and stimulators of polymerase activity of E. coli DNA polymerase I Klenow fragment. I A Potapova, G A Nevinsky, V V Khomov, Olga I Lavrik FEBS letters 1990 pols set
Highly selective affinity labeling of the primer-binding site of E. coli DNA polymerase I. R L Mitina, A A Mustaev, E F Zaychikov, V V Khomov, Olga I Lavrik FEBS letters 1990 pols set
Processing of the primer for plus strand DNA synthesis by human immunodeficiency virus 1 reverse transcriptase. H E Huber, Charles C Richardson The Journal of biological chemistry 1990 new
Genetic evidence for two protein domains and a potential new activity in bacteriophage T4 DNA polymerase. Linda J Reha-Krantz Genetics 1990 complete
Site-directed mutagenesis of Moloney murine leukemia virus reverse transcriptase. Demonstration of lysine 103 in the nucleotide binding site. A Basu, S Basu, Mukund J Modak The Journal of biological chemistry 1990 new
Site-specific mutagenesis of a highly conserved region of the herpes simplex virus type 1 DNA polymerase gene. D I Dorsky, C S Crumpacker J Virol 1990 new
The herpes simplex virus type 1 UL42 gene product: a subunit of DNA polymerase that functions to increase processivity. J Gottlieb, A I Marcy, Donald M Coen, M D Challberg J Virol 1990 new
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. C Tuerk, L Gold Science 1990 topics set
Neutralization of purified herpes simplex virus DNA polymerase by two antipeptide sera. J T Matthews, J T Stevens, B J Terry, C W Cianci, M L Haffey Virus genes 1990 new
Human DNA polymerase alpha catalytic polypeptide binds ConA and RCA and contains a specific labile site in the N-terminus. K L Hsi, William C Copeland, Teresa S-F Wang Nucleic acids research 1990 pols set
Resistance to infection by HIV-1 of peripheral blood mononuclear cells from HIV-1-infected patients is probably mediated by neutralizing antibodies. M Tremblay, K Numazaki, X G Li, M Gornitsky, J Hiscott, Mark A. Wainberg Journal of immunology (Baltimore, Md. : 1950) 1990 pols set
[Klenow fragment of DNA-polymerase I from E. coli. III. The role of internucleotide phosphate groups of the matrix in its binding with the enzyme]. V A Volchkova, V V Gorn, T I Kolocheva, Olga I Lavrik, A S Levina Bioorg Khim 1989 pols set
Fluorescent oligonucleotides and deoxynucleotide triphosphates: preparation and their interaction with the large (Klenow) fragment of Escherichia coli DNA polymerase I. D J Allen, P L Darke, Stephen J Benkovic Biochemistry 1989 topics set
Exonucleolytic proofreading by a mammalian DNA polymerase. Thomas A Kunkel, D W Mosbaugh Biochemistry 1989 partial results
Structural and enzymatic studies of the T4 DNA replication system. II. ATPase properties of the polymerase accessory protein complex. Thale C Jarvis, L S Paul, J W Hockensmith, Peter H von Hippel The Journal of biological chemistry 1989 complete
Highly specific inhibition of human immunodeficiency virus type 1 by a novel 6-substituted acyclouridine derivative. Masanori Baba, Hiromichi Tanaka, Erik De Clercq, Rudi Pauwels, Jan Balzarini, Dominique Schols, H Nakashima, CF Perno, R T Walker, T Miyasaka Biochemical and biophysical research communications 1989 pols set
Effect of pisiferic acid and its derivatives on cytotoxicity macromolecular synthesis and DNA polymerase alpha of HeLa cells. Kazuki Kobayashi, Kazufumi Kuroda, T Shinomiya, C Nishino, J Ohya, S Sato Int J Biochem 1989 new
REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymerase. A Morrison, R B Christensen, J Alley, A K Beck, E G Bernstine, J F Lemontt, Christopher W Lawrence Journal of bacteriology 1989 topics set
The algorithm of estimation of the Km values for primers of various structure and length in the polymerization reaction catalyzed by Klenow fragment of DNA polymerase I from E. coli. G A Nevinsky, A V Nemudraya, A S Levina, V V Khomov FEBS letters 1989 pols set
Herpes simplex-1 DNA polymerase. Identification of an intrinsic 5'----3' exonuclease with ribonuclease H activity. J J Crute, I. Robert Lehman The Journal of biological chemistry 1989 new
Stopping the DNA polymerase activity at a specific site with a dideoxyoligonucleotide: selective labelling of single stranded circular DNA. D Mattanovich, G Himmler, F Regner, M Laimer, H Steinkellner, F Rüker, H Katinger Nucleic acids research 1989 new
Repression of polyoma virus DNA replication by 5'-flanking region of mouse DNA polymerase beta gene containing transcriptional silencer elements. Masamitsu Yamaguchi, Akio Matsukage The Journal of biological chemistry 1989 new
Fidelity of DNA polymerases in DNA amplification. P Keohavong, William G Thilly Proceedings of the National Academy of Sciences of the United States of America 1989 complete
Substrate and DNA binding to a 50-residue peptide fragment of DNA polymerase I. Comparison with the enzyme. Gregory P Mullen, P Shenbagamurthi, A S Mildvan The Journal of biological chemistry 1989 new
Structure-activity relationships for the inhibition of DNA polymerase alpha by aphidicolin derivatives. G Prasad, R A Edelson, P D Gorycki, T L Macdonald Nucleic acids research 1989 new
Induction of beta-polymerase mRNA by DNA-damaging agents in Chinese hamster ovary cells. A J Fornace, B Z Zmudzka, M C Hollander, Samuel H Wilson Molecular and cellular biology 1989 new
1-beta-D-arabinofuranosyl-5-(E)-(4-azidostyryl)-uracil 5'-triphosphate: synthesis and utilization as a photoaffinity labeling reagent for DNA polymerase alpha from cherry salmon, Oncorhynchus masou. Shunji Izuta, Mineo Saneyoshi Biochem Biophys Res Commun 1989 new
Changes in activity and subcellular localization of alpha-like DNA polymerase during cell cycle of Physarum polycephalum. M Shioda, K Murakami-Murofushi Biochem Int 1989 new
Demonstration of the human herpesvirus 6-induced DNA polymerase and DNase. M V Williams, D V Ablashi, S Z Salahuddin, R Glaser Virology 1989 new
DNA polymerase from Sulfolobus acidocaldarius. Replication at high temperature of long stretches of single-stranded DNA. S Salhi, C Elie, P Forterre, A M de Recondo, J M Rossignol Journal of molecular biology 1989 new
Cell-type-specific expression of mouse DNA polymerase beta-gene is regulated by silencer elements. Masamitsu Yamaguchi, Y Hayashi, K Ajiro, Akio Matsukage Journal of cellular physiology 1989 new
[Characteristics of DNA isolated from a complex form of DNA-polymerase alpha from the rat liver]. N A Timchenko, N V Beliakova, L T Timchenko, V M Krutiakov Mol Biol (Mosk) 1989 new
Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase. Fred W Perrino, Bradley D Preston, L L Sandell, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1989 pols set
A conserved 3'----5' exonuclease active site in prokaryotic and eukaryotic DNA polymerases. Antonio Bernad, Luis Blanco, José María Lázaro, G Martín, Margarita Salas Cell 1989 pols set
Characterization of the polA gene of Streptococcus pneumoniae and comparison of the DNA polymerase I it encodes to homologous enzymes from Escherichia coli and phage T7. P Lopez, S Martinez, A Diaz, M Espinosa, S A Lacks The Journal of biological chemistry 1989 partial results
Locations of amino acid substitutions in bacteriophage T4 tsL56 DNA polymerase predict an N-terminal exonuclease domain. Linda J Reha-Krantz J Virol 1989 complete
[A study of the proliferative activity of DNA polymerase alpha immunoreactivity in breast cancer]. R Nishimura, K Nagao, M Matsuda, K Baba, Y Matsuoka, Y Ueno, H Morinaga, H Nagase, O Miyayama, T Hamada Gan No Rinsho 1989 new
Conditional lethality of the recA441 and recA730 mutants of Escherichia coli deficient in DNA polymerase I. I Fijalkowska, Piotr Jonczyk, Z Ciesla Mutation research 1989 new
Aphidicolin resistance in herpes simplex virus type 1 appears to alter substrate specificity in the DNA polymerase. J D Hall, S Woodward J Virol 1989 new
[Selective inhibition of 3'-5'-exonuclease activity of DNA-polymerase I from Escherichia coli by a fluoride ion]. V S Mikhaĭlov, D O Ataeva, K A Marlyev, A M Atrazhev Mol Biol (Mosk) 1989 pols set
The cloned polC gene of Bacillus subtilis: characterization of the azp12 mutation and controlled in vitro synthesis of active DNA polymerase III. Marjorie H Barnes, R A Hammond, Kimberly A Foster, J A Mitchener, Neal C Brown Gene 1989 new
Biochemistry of terminal deoxynucleotidyltransferase. Identification and unity of ribo- and deoxyribonucleoside triphosphate binding site in terminal deoxynucleotidyltransferase. V N Pandey, Mukund J Modak The Journal of biological chemistry 1989 new
The efficiency of interaction of deoxyribonucleoside-5'-mono-, di- and triphosphates with the active centre of E. coli DNA polymerase I Klenow fragment. S V Doronin, G A Nevinsky, T O Malygina, Vladimir N Podust, V V Khomov, Olga I Lavrik FEBS letters 1989 pols set
Polymerase-specific differences in the DNA intermediates of frameshift mutagenesis. In vitro synthesis errors of Escherichia coli DNA polymerase I and its large fragment derivative. C Papanicolaou, L S Ripley Journal of molecular biology 1989 partial results
Difference in the expression level of DNA polymerase beta among mouse tissues: high expression in the pachytene spermatocyte. Fumiko Hirose, Y Hotta, Masamitsu Yamaguchi, Akio Matsukage Exp Cell Res 1989 new
Age-related changes in DNA polymerase alpha expression. D Busbee, V Sylvia, G Curtin, S Peng, V Srivastava, R Tilley Exp Gerontol 1989 new
The Molecule of the Year. R L Guyer, D E Koshland Science (New York, N.Y.) 1989 topics set
A novel ochre mutation in the beta-thalassemia gene of a Thai. Identification by direct cloning of the entire beta-globin gene amplified using polymerase chain reactions. S Fucharoen, G Fucharoen, P Fucharoen, Y Fukumaki The Journal of biological chemistry 1989 pols set
Effect of phosphorothioate homo-oligodeoxynucleotides on herpes simplex virus type 2-induced DNA polymerase. W Y Gao, C A Stein, J S Cohen, Ginger E Dutschman, Yung-Chi Cheng The Journal of biological chemistry 1989 new
Levels of DNA topoisomerases, single-stranded-DNA-binding protein, and DNA polymerase I in rho+ and rho-15 strains of Escherichia coli. G F Arnold, T A Phillips, I Tessman J Bacteriol 1989 pols set
DNA polymerase alpha from normal rat liver is different than DNA polymerases alpha from Morris hepatoma strains. O Popanda, H W Thielmann Eur J Biochem 1989 new
Studies on the DNA elongation inhibitor and its proliferating cell nuclear antigen-dependent control in simian virus 40 DNA replication in vitro. Sang Hee Lee, A D Kwong, Y Ishimi, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1989 new
How DNA travels between the separate polymerase and 3'-5'-exonuclease sites of DNA polymerase I (Klenow fragment). Catherine M Joyce The Journal of biological chemistry 1989 new
Synthesis of DNA containing the simian virus 40 origin of replication by the combined action of DNA polymerases alpha and delta. Sang Hee Lee, Toshihiko Eki, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1989 new
Differential extension of 3' mispairs is a major contribution to the high fidelity of calf thymus DNA polymerase-alpha. Fred W Perrino, Lawrence A Loeb The Journal of biological chemistry 1989 new
In vitro mutagenesis of the herpes simplex virus type 1 DNA polymerase gene results in altered drug sensitivity of the enzyme. J T Matthews, R D Carroll, J T Stevens, M L Haffey J Virol 1989 new
Infection of cultured human thymic epithelial cells by human immunodeficiency virus. K Numazaki, X Q Bai, H Goldman, I Wong, Bonnie Spira, Mark A. Wainberg Clinical immunology and immunopathology 1989 pols set
Substrate binding in human immunodeficiency virus reverse transcriptase. An analysis of pyridoxal 5'-phosphate sensitivity and identification of lysine 263 in the substrate-binding domain. A Basu, R S Tirumalai, Mukund J Modak The Journal of biological chemistry 1989 pols set
Effects of internal deletions on the priming activity of the phage phi 29 terminal protein. A Zaballos, José María Lázaro, E Méndez, R P Mellado, Margarita Salas Gene 1989 pols set
Human immunodeficiency virus 1 reverse transcriptase. Template binding, processivity, strand displacement synthesis, and template switching. H E Huber, J M McCoy, J S Seehra, Charles C Richardson The Journal of biological chemistry 1989 partial results
Recognition and use of the unusual X-DNA as a primer-template by Klenow DNA polymerase enzyme. J Sági, M Vorlícková, J Kypr, L Otvös Biochem Biophys Res Commun 1989 new
Thermostable DNA polymerase from the archaebacterium Sulfolobus acidocaldarius. Purification, characterization and immunological properties. C Elie, A M de Recondo, P Forterre Eur J Biochem 1989 new
Specificity and mechanism of error-prone replication by human immunodeficiency virus-1 reverse transcriptase. Katarzyna Bebenek, J Abbotts, J D Roberts, Samuel H Wilson, Thomas A Kunkel The Journal of biological chemistry 1989 new
DNA primase-DNA polymerase alpha assembly from mouse FM3A cells. Purification of constituting enzymes, reconstitution, and analysis of RNA priming as coupled to DNA synthesis. Motoshi Suzuki, Takemi Enomoto, Chikahide Masutani, Fumio Hanaoka, Masami Yamada, M Ui The Journal of biological chemistry 1989 new
Resonance energy transfer measurements between substrate binding sites within the large (Klenow) fragment of Escherichia coli DNA polymerase I. D J Allen, Stephen J Benkovic Biochemistry 1989 pols set
Inactivation of human hepatitis B virus DNA polymerase by pyridoxal 5'-phosphate. S H Oh, Y H Park, K Woo J Med Virol 1989 new
Effect of manganese ions on the incorporation of dideoxynucleotides by bacteriophage T7 DNA polymerase and Escherichia coli DNA polymerase I. Stanley Tabor, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 1989 topics set
Dissection of functional domains of adenovirus DNA polymerase by linker-insertion mutagenesis. M Chen, M S Horwitz Proceedings of the National Academy of Sciences of the United States of America 1989 new
A kinetic study of rat recombinant DNA polymerase beta: detection of a slow (hysteretic) transition in polymerase activity and inhibition by butylphenyl-deoxyguanosine triphosphate. J A DiGiuseppe, George E Wright, S L Dresler Nucleic acids research 1989 pols set
Aphidicolin hypersensitive mutant of Chinese hamster V79 fibroblasts that underproduces DNA polymerase-alpha antigen. P K Liu, B Goudreau, G S Hsu Somat Cell Mol Genet 1989 new
Glutamate overcomes the salt inhibition of DNA polymerase III holoenzyme. Mark A Griep, Charles S McHenry The Journal of biological chemistry 1989 new
Sequence-specific pausing during in vitro DNA replication on double-stranded DNA templates. P Bedinger, M Munn, B M Alberts The Journal of biological chemistry 1989 complete
Interaction of phosphatidylinositol-4-monophosphate with a low activity form of DNA polymerase alpha: a potential mechanism for enzyme activation. V L Sylvia, C O Joe, J O Norman, G M Curtin, R D Tilley, David L Busbee Int J Biochem 1989 new
Inactivation of DNA polymerase I (Klenow fragment) by adenosine 2',3'-epoxide 5'-triphosphate: evidence for the formation of a tight-binding inhibitor. C E Catalano, Stephen J Benkovic Biochemistry 1989 pols set
Selective inactivation of the exonuclease activity of bacteriophage T7 DNA polymerase by in vitro mutagenesis. Stanley Tabor, Charles C Richardson The Journal of biological chemistry 1989 pols set
Control of DNA polymerase-alpha activity in regenerating rat liver by calcium and 1 alpha,25(OH)2D3. R H Rixon, R J Isaacs, J F Whitfield J Cell Physiol 1989 new
Rapid purification of overexpressed T4 DNA polymerase. J Rush, William H Konigsberg Prep Biochem 1989 pols set
[DNA polymerase I, Klenow fragment of Escherichia coli: hydrolysis and pyrophosphorolysis of DNA containing phosphothioate groups]. T A Rozovskaia, Sh Kh Minasian, M K Kukhanova, A A Kraevskiĭ, Z G Chidzhavadze Mol Biol (Mosk) 1989 pols set
Irradiation of the template with high-intensity (pulse-laser) ultraviolet light results in DNA-polymerase termination events at deoxyguanosine residues. I G Panyutin, O I Kovalsky, E I Budowsky FEBS letters 1989 new
Genomic footprinting in mammalian cells with ultraviolet light. M M Becker, Zhengqiang Wang, G Grossmann, K A Becherer Proceedings of the National Academy of Sciences of the United States of America 1989 pols set
Uracil-DNA glycosylase inhibitor gene of bacteriophage PBS2 encodes a binding protein specific for uracil-DNA glycosylase. Zhengqiang Wang, D W Mosbaugh The Journal of biological chemistry 1989 new
Low cost apparatus for primer-directed DNA amplification using Thermus aquaticus-DNA polymerase. H Torgersen, D Blaas, T Skern Anal Biochem 1989 new
DNA polymerase alpha activity is not affected by protein kinases or alkaline phosphatase. C E Prussak, B Y Tseng Biochem Biophys Res Commun 1989 new
[The effect of growth rate and culturing conditions on the stability of plasmid pCJ55 and on the level of expression of a large fragment of DNA-polymerase I, cloned in Escherichia coli]. E G Kriukova, V M Nikolaeva, E K Ustinova, V A Ezhov Mikrobiologiia 1989 pols set
Inhibitory effects of gold sodium thiomalate on DNA polymerase alpha. F Takeuchi, Fumio Hanaoka, K Matsuta, T Miyamoto Clin Exp Rheumatol 1989 new
Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT). Brendan A Larder, S D Kemp Science 1989 topics set
Cloning and sequencing of the nuclear gene MIP1 encoding the catalytic subunit of the yeast mitochondrial DNA polymerase. F Foury The Journal of biological chemistry 1989 pols set
Genetic requirements for hyper-recombination by very short patch mismatch repair: involvement of Escherichia coli DNA polymerase I. S Dzidic, Miroslav Radman Mol Gen Genet 1989 pols set
[Purification and characterization of DNA-dependent DNA-polymerase alpha from human placenta]. Olga I Lavrik, G A Nevinskiĭ, Vladimir N Podust, O V Khalabuda Mol Biol (Mosk) 1989 new
An unusual polyanion from Physarum polycephalum that inhibits homologous DNA polymerase alpha in vitro. H Fischer, S Erdmann, Eggehard Holler Biochemistry 1989 new
Levels and size complexity of DNA polymerase beta mRNA in rat regenerating liver and other organs. Radosława Nowak, Janusz A Siedlecki, L Kaczmarek, B Z Zmudzka, Samuel H Wilson Biochimica et biophysica acta 1989 new
Identification and some properties of a unique DNA polymerase from cells infected with human B-lymphotropic virus. A R Bapat, A J Bodner, R C Ting, Yung-Chi Cheng J Virol 1989 new
Analysis of c-Ki-ras mutations in human colon carcinoma by cell sorting, polymerase chain reaction, and DNA sequencing. G C Burmer, P S Rabinovitch, Lawrence A Loeb Cancer research 1989 new
Changes in the nuclear distribution of DNA polymerase alpha and PCNA/cyclin during the progress of the cell cycle, in a cell-free extract of Xenopus eggs. C Hutchison, I Kill J Cell Sci 1989 new
Eukaryotic DNA polymerases alpha and delta: conserved properties and interactions, from yeast to mammalian cells. Peter M J Burgers Prog Nucleic Acid Res Mol Biol 1989 new
Kinetic analysis of base substitution mutagenesis by transient misalignment of DNA and by miscoding. M S Boosalis, D W Mosbaugh, R Hamatake, Akio Sugino, Thomas A Kunkel, Myron F Goodman The Journal of biological chemistry 1989 new
The bacteriophage T4 DNA replication fork. Only DNA helicase is required for leading strand DNA synthesis by the DNA polymerase holoenzyme. T A Cha, B M Alberts The Journal of biological chemistry 1989 complete
Biochemical characterization of the DNA polymerase activity present in isolated nuclei from mussel tissues: a possible system for the evaluation of the rate of DNA repair. R Accomando, A Viarengo, A Zonchedu, M Orunesu Comp Biochem Physiol B 1989 new
Stepwise mechanism of HIV reverse transcriptase: primer function of phosphorothioate oligodeoxynucleotide. C Majumdar, C A Stein, J S Cohen, S Broder, Samuel H Wilson Biochemistry 1989 pols set
Conversion of monofunctional DNA adducts of cis-diamminedichloroplatinum (II) to bifunctional lesions. Effect on the in vitro replication of single-stranded DNA by Escherichia coli DNA polymerase I and eukaryotic DNA polymerases alpha. Jean-Sébastien Hoffmann, Neil P Johnson, Giuseppe Villani The Journal of biological chemistry 1989 pols set
Detection and characteristics of DNA polymerase activity in serum from patients with malignant, viral, or B12-deficiency disease. M Neumuller, C F Källander, J S Gronowitz Enzyme 1989 new
Purification of DNA polymerase II, a distinct DNA polymerase, from Saccharomyces cerevisiae. Martin E Budd, K C Sitney, Judith L Campbell The Journal of biological chemistry 1989 topics set
Effects of small insertions on the RNA-dependent DNA polymerase activity of HIV-1 reverse transcriptase. A Hizi, A Barber, Stephen H Hughes Virology 1989 pols set
A novel stimulating protein of mammalian DNA polymerase alpha. Shonen Yoshida, Katsuyuki Tamai, H Umekawa, Motoshi Suzuki, K Kojima J Biochem 1989 pols set
Herpes simplex virus type 1 and human DNA polymerase interactions with 2'-deoxyguanosine 5'-triphosphate analogues. Kinetics of incorporation into DNA and induction of inhibition. J E Reardon The Journal of biological chemistry 1989 pols set
DNA polymerase alpha-DNA primase from human placenta. Immunoaffinity purification and preliminary characterization. Vladimir N Podust, Olga I Lavrik, Heinz Peter Nasheuer, Frank Grosse FEBS letters 1989 pols set
Binding of captan to DNA polymerase I from Escherichia coli and the concomitant effect on 5'----3' exonuclease activity. M J Freeman-Wittig, W Welch, R A Lewis Biochemistry 1989 pols set
Stimulation of DNA chain initiation by a protein factor (NPF-1) from rat liver of different ages. S Basu, A T Rosado, S Takada, S Ray, Kalyan Das, I Suzuki, A P Seve Progress in clinical and biological research 1989 new
Site-directed mutagenesis by overlap extension using the polymerase chain reaction. S N Ho, H D Hunt, R M Horton, J K Pullen, L R Pease Gene 1989 new
RecA protein inhibits in vitro replication of single-stranded DNA with DNA polymerase III holoenzyme of Escherichia coli. H Shwartz, Zvi Livneh Mutation research 1989 pols set
Susceptibility of EBV-carrying B cell lines to infection by HIV-1: variability of production of progeny virus and expression of viral antigens. M Tremblay, Mark A. Wainberg Cancer letters 1989 pols set
The early history of DNA polymerase: a commentary on 'Enzymic Synthesis of Deoxyribonucleic Acid'. Arthur Kornberg Biochimica et biophysica acta 1989 new
Comparison of inhibitory activities of various antiretroviral agents against particle-derived and recombinant human immunodeficiency virus type 1 reverse transcriptases. Raymond F Schinazi, B F Eriksson, Stephen H Hughes Antimicrobial agents and chemotherapy 1989 new
DNA polymerase alpha. I. Robert Lehman, Laurie S Kaguni The Journal of biological chemistry 1989 new
The relationship between cell size, the activity of DNA polymerase alpha and proliferative activity in human diploid fibroblast-like cell cultures. W Pendergrass, J Angello, Thomas H Norwood Exp Gerontol 1989 new
The 44P subunit of the T4 DNA polymerase accessory protein complex catalyzes ATP hydrolysis. J Rush, T C Lin, M Quinones, E K Spicer, I Douglas, K R Williams, William H Konigsberg The Journal of biological chemistry 1989 pols set
Mutation induced in vitro on a C-8 guanine aminofluorene containing template by a modified T7 DNA polymerase. J Sahm, E Turkington, D LaPointe, Bernard Strauss Biochemistry 1989 pols set
Functional domains in the bacteriophage phi 29 terminal protein for interaction with the phi 29 DNA polymerase and with DNA. A Zaballos, Margarita Salas Nucleic acids research 1989 pols set
Progressive esophagitis from acyclovir-resistant herpes simplex. Clinical roles for DNA polymerase mutants and viral heterogeneity? S L Sacks, R J Wanklin, D E Reece, K A Hicks, K L Tyler, Donald M Coen Annals of internal medicine 1989 new
Immunochemical studies of DNA polymerase delta: relationships with DNA polymerase alpha. Marietta Y W T Lee, R Alejandro, N L Toomey Archives of biochemistry and biophysics 1989 new
The effect of medroxyprogesterone acetate on aromatase and DNA polymerase alpha activities in breast tumours. A Purohit, L C Lai, A Singh, N G Coldham, M W Ghilchik, M J Reed, V H James J Steroid Biochem 1989 new
Purification of Norman Murine Sarcoma DNA polymerase alpha forms with different DNA template primer binding affinity and different specific activity. V L Sylvia, J O Norman, G M Curtin, J Stec, David L Busbee Int J Biochem 1989 new
A novel primase-free form of murine DNA polymerase alpha induced by infection with minute virus of mice. T F Ho, J S Gupta, E A Faust Biochemistry 1989 new
[Lipid peroxidation and the endogenous DNA polymerase activity of fractions of isolated liver chromatin in rats]. Iu I Gubskiĭ, E L Levitskiĭ, N B Gol'dshteĭn, A Ia Litoshenko Biull Eksp Biol Med 1989 new
Carbonyldiphosphonate, a selective inhibitor of mammalian DNA polymerase delta. R V Talanian, Neal C Brown, Charles E McKenna, T G Ye, J N Levy, George E Wright Biochemistry 1989 pols set
Comparison of polymerase insertion and extension kinetics of a series of O2-alkyldeoxythymidine triphosphates and O4-methyldeoxythymidine triphosphate. B Singer, F Chavez, S J Spengler, J T Kuśmierek, L Mendelman, Myron F Goodman Biochemistry 1989 topics set
DNA polymerase III gene of Bacillus subtilis. B Sanjanwala, A T Ganesan Proceedings of the National Academy of Sciences of the United States of America 1989 partial results
Herpes simplex virus type 1 DNA polymerase. Mechanism of inhibition by acyclovir triphosphate. J E Reardon, T Spector The Journal of biological chemistry 1989 new
Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro. J D Roberts, Bradley D Preston, L A Johnston, A Soni, Lawrence A Loeb, Thomas A Kunkel Molecular and cellular biology 1989 partial results
[Genetic and biochemical studies on the mechanism of mammalian chromosome replication]. Fumio Hanaoka Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1989 new
Isolation, characterization, and expression in Escherichia coli of the DNA polymerase gene from Thermus aquaticus. F C Lawyer, S Stoffel, R K Saiki, K Myambo, R Drummond, D H Gelfand The Journal of biological chemistry 1989 topics set
Active replication of human immunodeficiency virus type 1 by peripheral blood mononuclear cells following coincubation with herpes viruses. M Tremblay, M Gornitsky, Mark A. Wainberg Journal of medical virology 1989 pols set
DNA polymerase I (Klenow fragment): role of the structure and length of a template in enzyme recognition. T I Kolocheva, G A Nevinsky, V A Volchkova, A S Levina, V V Khomov, Olga I Lavrik FEBS letters 1989 new
Proofreading by the epsilon subunit of Escherichia coli DNA polymerase III increases the fidelity of calf thymus DNA polymerase alpha. Fred W Perrino, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1989 pols set
The inhibition of P338 lymphocytic leukemia DNA polymerase alpha activity by cis-diamminedichloroplatinum(II) and related derivatives. C B Oswald, I H Hall Anticancer Res 1989 new
Growth hormone elevates DNA polymerase-alpha activity related to DNA synthesis in ovaries of hypophysectomized immature rat. S Usuki, M Shioda Horm Metab Res 1989 new
Fidelity of DNA polymerase I and the DNA polymerase I-DNA primase complex from Saccharomyces cerevisiae. Thomas A Kunkel, Robert K Hamatake, J Motto-Fox, M P Fitzgerald, Akio Sugino Molecular and cellular biology 1989 partial results
Sequence specificity of pausing by DNA polymerases. P Weisman-Shomer, D K Dube, Fred W Perrino, K Stokes, Lawrence A Loeb, M Fry Biochem Biophys Res Commun 1989 new
Regulation of the synthesis of DNA polymerase-alpha in regenerating liver by calcium and 1,25-dihydroxyvitamin D3. M Sikorska, I de Belle, J F Whitfield, P R Walker Biochem Cell Biol 1989 new
[Protein-nucleic acid interactions in reactions catalyzed by eukaryotic and prokaryotic DNA-polymerases]. Olga I Lavrik, G A Nevinskiĭ Biokhimii͡a (Moscow, Russia) 1989 new
Aphidicolin resistance in herpes simplex virus type I reveals features of the DNA polymerase dNTP binding site. J D Hall, Y S Wang, J Pierpont, M S Berlin, S E Rundlett, S Woodward Nucleic acids research 1989 new
Effect of 3' flanking neighbors on kinetics of pairing of dCTP or dTTP opposite O6-methylguanine in a defined primed oligonucleotide when Escherichia coli DNA polymerase I is used. B Singer, F Chavez, Myron F Goodman, John M Essigmann, M K Dosanjh Proceedings of the National Academy of Sciences of the United States of America 1989 pols set
Intact DNA polymerase alpha/primase from mouse cells. Purification and structure. Mehran Goulian, C J Heard The Journal of biological chemistry 1989 new
Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction. J L Weber, P E May Am J Hum Genet 1989 new
Potential drugs for the treatment of AIDS. Erik De Clercq The Journal of antimicrobial chemotherapy 1989 pols set
Mismatch-specific 3'----5' exonuclease associated with the mitochondrial DNA polymerase from Drosophila embryos. Laurie S Kaguni, M W Olson Proceedings of the National Academy of Sciences of the United States of America 1989 new
Trypsin cleavage in the COOH terminus of the bacteriophage T4 gene 41 DNA helicase alters the primase-helicase activities of the T4 replication complex in vitro. R W Richardson, Nancy G Nossal The Journal of biological chemistry 1989 complete
Antibody against Epstein-Barr virus DNA polymerase activity in sera of patients with nasopharyngeal carcinoma. M Y Liu, W H Chou, L Nutter, M M Hsu, J Y Chen, C S Yang J Med Virol 1989 pols set
DNA polymerase gamma from Xenopus laevis. I. The identification of a high molecular weight catalytic subunit by a novel DNA polymerase photolabeling procedure. N F Insdorf, Daniel F Bogenhagen The Journal of biological chemistry 1989 pols set
Highly efficient DNA synthesis by the phage phi 29 DNA polymerase. Symmetrical mode of DNA replication. Luis Blanco, Antonio Bernad, José María Lázaro, G Martín, C Garmendia, Margarita Salas The Journal of biological chemistry 1989 partial results
Selective abrogation of alloreactivity via priming in the presence of aphidicolin, a specific inhibitor of DNA polymerase. S Morecki, S Slavin, S A Ben-Sasson J Immunol 1989 new
Active-site modification of mammalian DNA polymerase beta with pyridoxal 5'-phosphate: mechanism of inhibition and identification of lysine 71 in the deoxynucleoside triphosphate binding pocket. A Basu, Padmini Kedar, Samuel H Wilson, Mukund J Modak Biochemistry 1989 pols set
Alterations in the phosphorylation and activity of DNA polymerase alpha correlate with the change in replicative DNA synthesis as quiescent cells re-enter the cell cycle. J Cripps-Wolfman, E C Henshaw, Robert A Bambara The Journal of biological chemistry 1989 new
[Modification of human DNA polymerase alpha by N-acetylimidazole]. Olga I Lavrik, G A Nevinskiĭ, I A Potapova, N B Tarusova, O V Khalabuda Mol Biol (Mosk) 1989 pols set
Detection of HBs antigen, DNA polymerase activity, and hepatitis B virus DNA in tears: relevance to hepatitis B transmission by tears. P Gastaud, C Baudouin, D Ouzan Br J Ophthalmol 1989 new
Comparison of initiating abilities of primers of different length in polymerization reactions catalyzed by DNA polymerases from thermoacidophilic archaebacteria. I S Bukhrashvili, D Z Chinchaladze, Olga I Lavrik, A S Levina, G A Nevinsky, D A Prangishvili Biochimica et biophysica acta 1989 pols set
DNA polymerase III, a second essential DNA polymerase, is encoded by the S. cerevisiae CDC2 gene. K C Sitney, Martin E Budd, Judith L Campbell Cell 1989 topics set
UmuC mutagenesis protein of Escherichia coli: purification and interaction with UmuD and UmuD'. Roger Woodgate, M Rajagopalan, Chengping Lu, H Echols Proceedings of the National Academy of Sciences of the United States of America 1989 new
Calf thymus DNA polymerase delta independent of proliferating cell nuclear antigen (PCNA). Federico Focher, M Gassmann, P Hafkemeyer, Elena Ferrari, Silvio Spadari, Ulrich Hübscher Nucleic acids research 1989 topics set
Differential inhibitory effects of several pyrimidine 2',3'-dideoxynucleoside 5'-triphosphates on the activities of reverse transcriptase and various cellular DNA polymerases. K Ono, H Nakane, Piet Herdewijn, Jan Balzarini, Erik De Clercq Molecular pharmacology 1989 new
An alternative nonradioactive method for labeling DNA using biotin. T Takahashi, T Mitsuda, K Okuda Analytical biochemistry 1989 new
Thioredoxin reductase-dependent insulin disulfide reduction by phage T7 DNA polymerase reflects dissociation of the enzyme into subunits. I Slaby, A Holmgren The Journal of biological chemistry 1989 pols set
The use of native T7 DNA polymerase for site-directed mutagenesis. Katarzyna Bebenek, Thomas A Kunkel Nucleic acids research 1989 pols set
Characterization of a large form of DNA polymerase delta from HeLa cells that is insensitive to proliferating cell nuclear antigen. J Syvaoja, Stuart Linn The Journal of biological chemistry 1989 partial results
Nucleoside 5'-triphosphates modified at sugar residues as substrates for DNA polymerase from the thermoacidophilic archaebacterium Sulfolobus acidocaldarius. D Z Chinchaladze, D A Prangishvili, A V Scamrov, R S Beabealashvili, N B Dyatkina, A A Krayevsky Biochimica et biophysica acta 1989 new
Re-examination by improved reverse transcriptase assay of DNA polymerase in platelets from myelodysplastic disease patients. Shonen Yoshida, Hidetaka Yamada, T Sakurai, Motoshi Suzuki, K Kojima Biochemistry international 1989 new
Contribution of DNA polymerase delta to DNA replication in permeable CHO cells synchronized in S phase. A Basnakian, G Banfalvi, N Sarkar Nucleic acids research 1989 new
Multiple functions of human single-stranded-DNA binding protein in simian virus 40 DNA replication: single-strand stabilization and stimulation of DNA polymerases alpha and delta. M K Kenny, Sang Hee Lee, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1989 new
Use of polymerase chain reaction catalyzed by Taq DNA polymerase for site-specific mutagenesis. H Kadowaki, T Kadowaki, F E Wondisford, S I Taylor Gene 1989 pols set
The mechanisms of the inhibitory effects of liver extract on lymphocyte proliferation. III. The effects of arginase on DNA polymerase activities. H L Su, M H Huang, C L Yu, S H Han, B N Chiang, S R Wang Immunopharmacology 1989 new
[Covalent labelling of the Klenow fragment of DNA-polymerase I from E. coli]. S Kh Degtiarev, E F Zaĭchikov, O I Lavruk, R L Mitina, A A Mustaev, V A Rikhter Bioorg Khim 1989 pols set
Tumor necrosis factor enhances replication of human immunodeficiency virus (HIV) in vitro. M Ito, Masanori Baba, A Sato, K Hirabayashi, F Tanabe, S Shigeta, Erik De Clercq Biochemical and biophysical research communications 1989 pols set
Treatment of bovine leukaemia virus-infected sheep with suramin: an animal model for the development of antiretroviral compounds. H Burkhardt, S Rosenthal, H A Rosenthal, E Karge, Erik De Clercq Acta virologica 1989 new
Characterization of the helicase and primase activities of the 63-kDa component of the bacteriophage T7 gene 4 protein. J A Bernstein, Charles C Richardson The Journal of biological chemistry 1989 pols set
Paradoxical effect of Simian virus 40 enhancer on the function of mouse DNA polymerase beta gene promoter. Masamitsu Yamaguchi, Y Obata, Akio Matsukage Nucleic acids research 1989 new
Azidothymidine triphosphate is an inhibitor of both human immunodeficiency virus type 1 reverse transcriptase and DNA polymerase gamma. H König, E Behr, J Löwer, R Kurth Antimicrob Agents Chemother 1989 new
ATP interactions of the tau and gamma subunits of DNA polymerase III holoenzyme of Escherichia coli. Z Tsuchihashi, Arthur Kornberg The Journal of biological chemistry 1989 pols set
Selective activity of several cholic acid derivatives against human immunodeficiency virus replication in vitro. Masanori Baba, Dominique Schols, H Nakashima, Rudi Pauwels, G Parmentier, D K Meijer, Erik De Clercq Journal of acquired immune deficiency syndromes 1989 pols set
Flow cytometric method to demonstrate whether anti-HIV-1 agents inhibit virion binding to T4+ cells. Dominique Schols, Masanori Baba, Rudi Pauwels, Erik De Clercq Journal of acquired immune deficiency syndromes 1989 pols set
Recognition and binding of template-primers containing defined abasic sites by Drosophila DNA polymerase alpha holoenzyme. L Ng, S J Weiss, Paul A Fisher The Journal of biological chemistry 1989 pols set
The beta subunit modulates bypass and termination at UV lesions during in vitro replication with DNA polymerase III holoenzyme of Escherichia coli. O Shavitt, Zvi Livneh The Journal of biological chemistry 1989 pols set
Structure and function of the Saccharomyces cerevisiae CDC2 gene encoding the large subunit of DNA polymerase III. A Boulet, M Simon, G Faye, G A Bauer, Peter M J Burgers The EMBO journal 1989 pols set
A distinct form of ribonuclease H from calf thymus stimulates its homologous DNA-polymerase-alpha-primase complex. A Hagemeier, Frank Grosse Eur J Biochem 1989 new
DNA polymerase I is required for premeiotic DNA replication and sporulation but not for X-ray repair in Saccharomyces cerevisiae. Martin E Budd, K D Wittrup, J E Bailey, Judith L Campbell Molecular and cellular biology 1989 pols set
Segregation of relaxed replicated dimers when DNA ligase and DNA polymerase I are limited during oriC-specific DNA replication. B R Munson, P G Maier, R S Greene J Bacteriol 1989 new
Comparison of serum hepatitis B virus replication markers in patients with chronic hepatitis B: studies on HBeAg/anti-HBe system, viral DNA polymerase and HBV-DNA. J R Pinho, L E da Fonseca, Y Song, Y Miyamoto, F J Carrilho, C F Granato, L C da Silva Rev Inst Med Trop Sao Paulo 1989 new
DNA polymerase gamma from Xenopus laevis. II. A 3'----5' exonuclease is tightly associated with the DNA polymerase activity. N F Insdorf, Daniel F Bogenhagen The Journal of biological chemistry 1989 topics set
Co-expression of the subunits of the heterodimer of HIV-1 reverse transcriptase in Escherichia coli. B Müller, Tobias Restle, S Weiss, M Gautel, G Sczakiel, R S Goody The Journal of biological chemistry 1989 new
Mechanism of inhibition of adenovirus DNA replication by the acyclic nucleoside triphosphate analogue (S)-HPMPApp: influence of the adenovirus DNA binding protein. Y M Mul, R T van Miltenburg, Erik De Clercq, Peter C van der Vliet Nucleic acids research 1989 new
Dual cis-acting negative regulatory elements located upstream of the mouse DNA polymerase beta gene. Masamitsu Yamaguchi, Y Hayashi, Akio Matsukage J Biochem 1989 new
Serological pattern of hepatitis B virus markers (HBsAg, anti-HBs, IgM anti-HBc and HBV specific DNA polymerase) in leprosy patients. K D Moudgil, M Irshad, B M Gandhi, R Mishra Indian J Lepr 1989 new
DNA primase isolated from the yeast DNA primase-DNA polymerase complex. Immunoaffinity purification and analysis of RNA primer synthesis. M Brooks, L B Dumas The Journal of biological chemistry 1989 new
Nearest neighbor influences on DNA polymerase insertion fidelity. L V Mendelman, M S Boosalis, John Petruska, Myron F Goodman The Journal of biological chemistry 1989 new
Spontaneous and UV-induced mutations in Escherichia coli K-12 strains with altered or absent DNA polymerase I. H Bates, S K Randall, C Rayssiguier, Bryn A Bridges, Myron F Goodman, Miroslav Radman Journal of bacteriology 1989 new
The essential 65-kilodalton DNA-binding protein of herpes simplex virus stimulates the virus-encoded DNA polymerase. M L Gallo, D I Dorsky, C S Crumpacker, Deborah S Parris J Virol 1989 new
Calcium-dependent calmodulin-binding proteins associated with mammalian DNA polymerase alpha. R A Hammond, Kimberly A Foster, M W Berchthold, M Gassmann, A M. Holmes, Ulrich Hübscher, Neal C Brown Biochimica et biophysica acta 1988 pols set
DNA polymerase III from Saccharomyces cerevisiae. II. Inhibitor studies and comparison with DNA polymerases I and II. Peter M J Burgers, G A Bauer The Journal of biological chemistry 1988 pols set
Protein-protein interactions of yeast DNA polymerase III with mammalian and yeast proliferating cell nuclear antigen (PCNA)/cyclin. G A Bauer, Peter M J Burgers Biochimica et biophysica acta 1988 pols set
Hormonal regulation of DNA polymerase-beta activity in the rat thyroid gland. Akio Nagasaka, Shonen Yoshida, Akira Nakai, T Ohyama, K Iwase, Seiji Ohtani, H Nakagawa, R Masunaga, S Kato, T Kawabe J Endocrinol 1988 new
Affinity labeling the DNA polymerase alpha complex. I. Pyridoxal 5'-phosphate inhibition of DNA polymerase and DNA primase activities of the DNA polymerase alpha complex from Drosophila melanogaster embryos. J F Diffley The Journal of biological chemistry 1988 new
Purification and characterization of bacteriophage N4-induced DNA polymerase. G K Lindberg, J K Rist, Thomas A Kunkel, Akio Sugino, L B Rothman-Denes The Journal of biological chemistry 1988 new
Macromolecular crowding extends the range of conditions under which DNA polymerase is functional. S B Zimmerman, S O Trach Biochimica et biophysica acta 1988 pols set
DNA polymerase III from Saccharomyces cerevisiae. I. Purification and characterization. G A Bauer, H M Heller, Peter M J Burgers The Journal of biological chemistry 1988 topics set
DNA-polymerase activity detected in situ. Relationship between incorporation of 3H-deoxytriphosphates and 3H-actinomycin D binding during the cell cycle in antheridial filaments of Chara vulgaris L. Effect of auxin and cytokinins. M Godlewski Histochemistry 1988 new
DNA repair synthesis in human fibroblasts requires DNA polymerase delta. C Nishida, P Reinhard, Stuart Linn The Journal of biological chemistry 1988 new
DNA polymerase III holoenzyme of Escherichia coli. III. Distinctive processive polymerases reconstituted from purified subunits. Satoko Maki, Arthur Kornberg The Journal of biological chemistry 1988 pols set
Herpes simplex virus replication in the presence of DNA polymerase alpha inhibitors. M G Romanelli, P F Pignatti Virus Res 1988 pols set
DNA repair synthesis in mouse spermatogenesis involves DNA polymerase beta activity. P Orlando, R Geremia, C Frusciante, B Tedeschi, P Grippo Cell Differ 1988 new
Inhibition of DNA polymerase alpha by aphidicolin derivatives. L Arabshahi, N Brown, N Khan, G Wright Nucleic acids research 1988 new
Differential inhibition of various mammalian DNA polymerase activities by ammonium 21-tungsto-9-antimoniate (HPA23). K Ono, H Nakane, F Barré-Sinoussi, J C Chermann Eur J Biochem 1988 pols set
Initiation of DNA replication at cloned origins of bacteriophage T7. S D Rabkin, Charles C Richardson Journal of molecular biology 1988 pols set
Fidelity of a human cell DNA replication complex. J D Roberts, Thomas A Kunkel Proceedings of the National Academy of Sciences of the United States of America 1988 pols set
Leading and lagging strand synthesis at the replication fork of bacteriophage T7. Distinct properties of T7 gene 4 protein as a helicase and primase. H Nakai, Charles C Richardson The Journal of biological chemistry 1988 new
Expression of soluble, enzymatically active, human immunodeficiency virus reverse transcriptase in Escherichia coli and analysis of mutants. A Hizi, C McGill, Stephen H Hughes Proceedings of the National Academy of Sciences of the United States of America 1988 pols set
Collection of informative bacteriophage T4 DNA polymerase mutants Book: DNA Replication and Mutagenesis 1988 complete
Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. R K Saiki, D H Gelfand, S Stoffel, S J Scharf, R Higuchi, G T Horn, K B Mullis, H A Erlich Science 1988 complete
A DNA polymerase from a thermoacidophilic archaebacterium: evolutionary and technological interests. C Elie, S Salhi, J M Rossignol, P Forterre, A M de Recondo Biochimica et biophysica acta 1988 new
Affinity labeling of Escherichia coli DNA polymerase I by 5'-fluorosulfonylbenzoyladenosine. Identification of the domain essential for polymerization and Arg-682 as the site of reactivity. V N Pandey, Mukund J Modak The Journal of biological chemistry 1988 pols set
Specificity of proofreading by the 3'----5' exonuclease of the DNA polymerase-primase of Drosophila melanogaster. M E Reyland, I. Robert Lehman, Lawrence A Loeb The Journal of biological chemistry 1988 new
DNA polymerase alpha activity in mitogen-activated lymphocytes. J Stec, D Busbee Biochem Biophys Res Commun 1988 new
Stimulation of DNA replication by growth factor and hormones in Swiss 3T3 cells: comparison of the rate of entry into S phase with in vitro DNA synthesis and DNA polymerase alpha activity. A M Otto, C Smith, L Jimenez de Asua J Cell Physiol 1988 new
[The enzymes and genes participating in DNA replication of animal cells. Regulation of DNA polymerase beta gene expression and its physiological significance]. Masamitsu Yamaguchi, Fumiko Hirose Tanpakushitsu Kakusan Koso 1988 new
Purification and characterization of an inducible Escherichia coli DNA polymerase capable of insertion and bypass at abasic lesions in DNA. C A Bonner, S K Randall, C Rayssiguier, Miroslav Radman, R Eritja, B E Kaplan, K McEntee, Myron F Goodman The Journal of biological chemistry 1988 partial results
AraUTP-Affi-Gel 10: a novel affinity absorbent for the specific purification of DNA polymerase alpha-primase. Shunji Izuta, Mineo Saneyoshi Anal Biochem 1988 new
Involvement of DNA polymerase delta in DNA repair synthesis in human fibroblasts at late times after ultraviolet irradiation. S L Dresler, B J Gowans, R M Robinson-Hill, D J Hunting Biochemistry 1988 new
The asymmetric dimeric polymerase hypothesis: a progress report. Charles S McHenry Biochimica et biophysica acta 1988 new
DNA polymerase III holoenzyme of Escherichia coli. Charles S McHenry Annual review of biochemistry 1988 pols set
Mechanisms of error discrimination by Escherichia coli DNA polymerase I. W S el-Deiry, Antero G So, Kathleen M Downey Biochemistry 1988 pols set
Studies on the mechanism of Escherichia coli DNA polymerase I large fragment. Effect of template sequence and substrate variation on termination of synthesis. J Abbotts, Dibyendu Narayan SenGupta, G Zon, Samuel H Wilson The Journal of biological chemistry 1988 pols set
Affinity labeling the DNA polymerase alpha complex. Identification of subunits containing the DNA polymerase active site and an important regulatory nucleotide-binding site. J F Diffley The Journal of biological chemistry 1988 new
Expression in Escherichia coli of a Moloney murine leukemia virus reverse transcriptase whose structure closely resembles the viral enzyme. A Hizi, Stephen H Hughes Gene 1988 new
Eukaryotic DNA polymerase-primase: structure, mechanism and function. Laurie S Kaguni, I. Robert Lehman Biochimica et biophysica acta 1988 new
Initiation of phage phi 29 DNA replication by mutants with deletions at the amino end of the terminal protein. A Zaballos, R P Mellado, Margarita Salas Gene 1988 pols set
The yeast analog of mammalian cyclin/proliferating-cell nuclear antigen interacts with mammalian DNA polymerase delta. G A Bauer, Peter M J Burgers Proceedings of the National Academy of Sciences of the United States of America 1988 topics set
Interaction of Epstein-Barr virus DNA polymerase with aphidicolin, phosphonoformate and 5'-GMP. J S Li, Yung-Chi Cheng Virus genes 1988 new
Expression of active rat DNA polymerase beta in Escherichia coli. T Date, Masamitsu Yamaguchi, Fumiko Hirose, Y Nishimoto, K Tanihara, Akio Matsukage Biochemistry 1988 pols set
DNA Polymerase III holoenzyme of Escherichia coli. IV. The holoenzyme is an asymmetric dimer with twin active sites. Hisaji Maki, Satoko Maki, Arthur Kornberg The Journal of biological chemistry 1988 pols set
Mitochondrial DNA polymerase from Drosophila melanogaster embryos: kinetics, processivity, and fidelity of DNA polymerization. C M Wernette, M C Conway, Laurie S Kaguni Biochemistry 1988 new
The herpes simplex virus DNA polymerase: analysis of the functional domains. Charles W Knopf, Klaus Weisshart Biochimica et biophysica acta 1988 new
Protein-nucleic acid interaction in reactions catalyzed with DNA polymerases. D G Knorre, Olga I Lavrik, G A Nevinsky Biochimie 1988 new
Site-directed mutagenesis with Escherichia coli DNA polymerase III holoenzyme. N Tsurushita, Hisaji Maki, L J Korn Gene 1988 pols set
Optimal conditions for supercoil DNA sequencing with the Escherichia coli DNA polymerase I large fragment. H M Lim, J J Pène Gene Anal Tech 1988 pols set
Identification of amino acids in herpes simplex virus DNA polymerase involved in substrate and drug recognition. J S Gibbs, H C Chiou, K F Bastow, Yung-Chi Cheng, Donald M Coen Proceedings of the National Academy of Sciences of the United States of America 1988 new
Complete enzymatic synthesis of DNA containing the SV40 origin of replication. Y Ishimi, A Claude, P Bullock, Jerard Hurwitz The Journal of biological chemistry 1988 new
Influence of divalent metal activator on the specificity of misincorporation during DNA synthesis catalyzed by DNA polymerase I of Escherichia coli. M D Lai, K L Beattie Mutation research 1988 pols set
Genetic and crystallographic studies of the 3',5'-exonucleolytic site of DNA polymerase I. V Derbyshire, P S Freemont, M R Sanderson, L Beese, J M Friedman, Catherine M Joyce, Thomas A Steitz Science 1988 complete
DNA sequences of random origin as probes of Escherichia coli promoter architecture. M S Horwitz, Lawrence A Loeb The Journal of biological chemistry 1988 new
On the type of DNA polymerase activity in neuronal, astroglial, and oligodendroglial cell fractions from young, adult, and old rat brains. K Subrahmanyam, Kalluri Subba Rao Biochem Int 1988 new
Detection of an epitope, not required for polymerization, that is conserved between E.coli DNA polymerases I and III and bacteriophage T4 DNA polymerase. M A Franden, Charles S McHenry Nucleic acids research 1988 pols set
Exonucleolytic proofreading. Thomas A Kunkel Cell 1988 topics set
Exonucleolytic proofreading enhances the fidelity of DNA synthesis by chick embryo DNA polymerase-gamma. Thomas A Kunkel, A Soni The Journal of biological chemistry 1988 new
DNA sequencing with Thermus aquaticus DNA polymerase and direct sequencing of polymerase chain reaction-amplified DNA. M A Innis, K B Myambo, D H Gelfand, M A Brow Proceedings of the National Academy of Sciences of the United States of America 1988 topics set
[The enzymes and genes participating in DNA replication of animal cells. DNA polymerase alpha and its gene]. R Takayama, Fumio Hanaoka, M Ui Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1988 new
Human beta-polymerase gene. Structure of the 5'-flanking region and active promoter. S G Widen, Padmini Kedar, Samuel H Wilson The Journal of biological chemistry 1988 new
Studies on the mechanism of human immunodeficiency virus reverse transcriptase. Steady-state kinetics, processivity, and polynucleotide inhibition. C Majumdar, J Abbotts, S Broder, Samuel H Wilson The Journal of biological chemistry 1988 new
Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase. K R Tindall, Thomas A Kunkel Biochemistry 1988 partial results
Purification of the herpes simplex virus type 1 65-kilodalton DNA-binding protein: properties of the protein and evidence of its association with the virus-encoded DNA polymerase. M L Gallo, D H Jackwood, Mary C Murphy, Howard S Marsden, Deborah S Parris J Virol 1988 new
Protein-primed replication of bacteriophage phi 29 DNA. Margarita Salas, G Martín, Antonio Bernad, C Garmendia, José María Lázaro, A Zaballos, M Serrano, M J Otero, J Gutiérrez, E Parés Biochimica et biophysica acta 1988 new
The effect of the T7 and Escherichia coli DNA-binding proteins at the replication fork of bacteriophage T7. H Nakai, Charles C Richardson The Journal of biological chemistry 1988 pols set
Structural study of immunoaffinity-purified DNA polymerase alpha-DNA primase complex from calf thymus. Katsuyuki Tamai, K Kojima, T Hanaichi, S Masaki, Motoshi Suzuki, H Umekawa, Shonen Yoshida Biochimica et biophysica acta 1988 new
Subcellular localization of DNA polymerase gamma and changes in its activity in sea urchin embryos. M Shioda Comp Biochem Physiol B 1988 new
DNA primase activity found in an alpha-like DNA polymerase obtained from Halobacterium halobium. M Nakayama, K Ben-Mahrez, M Kohiyama Eur J Biochem 1988 new
The fidelity of base selection by the polymerase subunit of DNA polymerase III holoenzyme. D L Sloane, Myron F Goodman, H Echols Nucleic acids research 1988 pols set
Primary structure of T4 DNA polymerase. Evolutionary relatedness to eucaryotic and other procaryotic DNA polymerases. E K Spicer, J Rush, C Fung, Linda J Reha-Krantz, Jim D Karam, William H Konigsberg The Journal of biological chemistry 1988 complete
Factor D is a selective single-stranded oligodeoxythymidine binding protein. M Fry, Fred W Perrino, A Levy, Lawrence A Loeb Nucleic acids research 1988 new
Amino acid changes coded by bacteriophage T4 DNA polymerase mutator mutants. Relating structure to function. Linda J Reha-Krantz Journal of molecular biology 1988 complete
Studies on the role of the phi X174 gene A protein in phi X viral strand synthesis. II. Effects of DNA replication of mutations in the 30-nucleotide icosahedral bacteriophage origin. G S Goetz, T Schmidt-Glenewinkel, M H Hu, N Belgado, Jerard Hurwitz The Journal of biological chemistry 1988 pols set
Studies on the role of the phi X174 gene A protein in phi X viral strand synthesis. I. Replication of DNA containing an alteration in position 1 of the 30-nucleotide icosahedral bacteriophage origin. G S Goetz, Jerard Hurwitz The Journal of biological chemistry 1988 pols set
Initiation of adenovirus DNA replication. II. Structural requirements using synthetic oligonucleotide adenovirus templates. M K Kenny, Jerard Hurwitz The Journal of biological chemistry 1988 new
Initiation of adenovirus DNA replication. I. Mechanism of action of a host protein required for replication of adenovirus DNA templates devoid of the terminal protein. M K Kenny, L A Balogh, Jerard Hurwitz The Journal of biological chemistry 1988 new
The accuracy of reverse transcriptase from HIV-1. J D Roberts, Katarzyna Bebenek, Thomas A Kunkel Science (New York, N.Y.) 1988 pols set
Dihydrothymidine and thymidine glycol triphosphates as substrates for DNA polymerases: differential recognition of thymine C5-C6 bond saturation and sequence specificity of incorporation. Hiroshi Ide, Susan S Wallace Nucleic acids research 1988 topics set
Nuclear transport of adenovirus DNA polymerase is facilitated by interaction with preterminal protein. L J Zhao, R Padmanabhan Cell 1988 new
An E. coli promoter that regulates transcription by DNA superhelix-induced cruciform extrusion. M S Horwitz, Lawrence A Loeb Science 1988 new
Sites of termination of in vitro DNA synthesis on cis-diamminedichloroplatinum(II) treated single-stranded DNA: a comparison between E. coli DNA polymerase I and eucaryotic DNA polymerases alpha. Giuseppe Villani, Ulrich Hübscher, J L Butour Nucleic acids research 1988 pols set
Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus. U B Gyllensten, H A Erlich Proceedings of the National Academy of Sciences of the United States of America 1988 new
DNA binding domain of Escherichia coli DNA polymerase I: identification of arginine-841 as an essential residue. P M Mohan, A Basu, S Basu, K I Abraham, Mukund J Modak Biochemistry 1988 pols set
Effects of 1-beta-D-arabinofuranosylcytosine incorporation on elongation of specific DNA sequences by DNA polymerase beta. Y Ohno, D Spriggs, Akio Matsukage, T Ohno, D Kufe Cancer research 1988 new
Inhibition of human hepatitis B virus DNA polymerase and duck hepatitis B virus DNA polymerase by triphosphates of thymidine analogs and pharmacokinetic properties of the corresponding nucleosides. P Z Tao, B Löfgren, D Lake-Bakaar, N G Johansson, R Datema, Bo Oberg J Med Virol 1988 new
DNA polymerase III holoenzyme of Escherichia coli. II. A novel complex including the gamma subunit essential for processive synthesis. Satoko Maki, Arthur Kornberg The Journal of biological chemistry 1988 pols set
[Modification of tyrosine residues of the Klenow fragment of DNA-polymerase I from Escherichia coli by acetylimidazole]. Olga I Lavrik, G A Nevinskiĭ, I A Potapova, V V Khomov Mol Biol (Mosk) 1988 pols set
Activation of a low specific activity form of DNA polymerase alpha by inositol-1,4-bisphosphate. V Sylvia, G Curtin, J Norman, J Stec, D Busbee Cell 1988 new
Induction of mutation in mouse FM3A cells by N4-aminocytidine-mediated replicational errors. Mayumi Takahashi, Masatoyo Nishizawa, Kazuo Negishi, Fumio Hanaoka, M A Yamada, H Hayatsu Molecular and cellular biology 1988 new
Analysis of the transcript of the herpes simplex virus DNA polymerase gene provides evidence that polymerase expression is inefficient at the level of translation. D R Yager, Donald M Coen Journal of virology 1988 new
Expression of herpes simplex virus type 1 DNA polymerase in Saccharomyces cerevisiae and detection of virus-specific enzyme activity in cell-free lysates. M L Haffey, J T Stevens, B J Terry, D I Dorsky, C S Crumpacker, S M Wietstock, W T Ruyechan, A K Field J Virol 1988 new
DNA polymerase of bacteriophage T4 is an autogenous translational repressor. M Andrake, N Guild, Tien Hsu, L Gold, C Tuerk, J Karam Proceedings of the National Academy of Sciences of the United States of America 1988 new
Expression of human DNA polymerase beta in Escherichia coli and characterization of the recombinant enzyme. J Abbotts, Dibyendu Narayan SenGupta, B Z Zmudzka, S G Widen, V Notario, Samuel H Wilson Biochemistry 1988 partial results
Replication of single-stranded porcine circovirus DNA by DNA polymerases alpha and delta. M Gassmann, Federico Focher, H J Buhk, Elena Ferrari, Silvio Spadari, Ulrich Hübscher Biochimica et biophysica acta 1988 new
Do DNA polymerases delta and alpha act coordinately as leading and lagging strand replicases? Federico Focher, Elena Ferrari, Silvio Spadari, Ulrich Hübscher FEBS letters 1988 new
The use of large-fragment DNA polymerase I improves the DNAse dependence of the in situ nick-translation procedure. A de Graaf, F J van Hemert Nucleic acids research 1988 new
Acetylated HMG1 protein interacts specifically with homologous DNA polymerase alpha in vitro. E A Alexandrova, B G Beltchev Biochem Biophys Res Commun 1988 new
DNA amplification in vitro using T4 DNA polymerase. P Keohavong, A G Kat, N F Cariello, William G Thilly DNA 1988 pols set
ABC excinuclease incises both 5' and 3' to the CC-1065-DNA adduct and its incision activity is stimulated by DNA helicase II and DNA polymerase I. C P Selby, A Sancar Biochemistry 1988 new
The duck hepatitis B virus DNA polymerase is tightly associated with the viral core structure and unable to switch to an exogenous template. G Radziwill, H Zentgraf, H Schaller, V Bosch Virology 1988 new
Pyridoxal 5'-phosphate mediated inactivation of Escherichia coli DNA polymerase I: identification of lysine-635 as an essential residue for the processive mode of DNA synthesis. S Basu, A Basu, Mukund J Modak Biochemistry 1988 pols set
Thymidine uptake, incorporation and DNA polymerase activity in murine bladder tumor cell, MBT-2, exposed to UV activated dihematoporphyrin ether. M T Tseng, Y H Ling, J I Harty Photochem Photobiol 1988 new
Effects of coordination of diammineplatinum(II) with DNA on the activities of Escherichia coli DNA polymerase I. F Bernges, Eggehard Holler Biochemistry 1988 pols set
Second-strand cDNA synthesis with E. coli DNA polymerase I and RNase H: the fate of information at the mRNA 5' terminus and the effect of E. coli DNA ligase. J M D'Alessio, G F Gerard Nucleic acids research 1988 partial results
Kinetic mechanism whereby DNA polymerase I (Klenow) replicates DNA with high fidelity. Robert D Kuchta, P Benkovic, Stephen J Benkovic Biochemistry 1988 new
DNA polymerase I activity in Escherichia coli is influenced by spot 42 RNA. D A Polayes, P W Rice, J E Dahlberg J Bacteriol 1988 new
Identification and subcellular localization of the polypeptide for chick DNA primase with a specific monoclonal antibody. Fumiko Hirose, S Yamamoto, Masamitsu Yamaguchi, Akio Matsukage The Journal of biological chemistry 1988 new
The evolutionary conservation of DNA polymerase alpha. M A Miller, D Korn, Teresa S-F Wang Nucleic acids research 1988 new
Low toxicity cancer chemotherapy by suicide inactivation of DNA polymerase alpha holoenzyme: first results with new thiazolidinyl- and perhydrothiazinyl-ethyl-N-mustard-phosphamide esters. H J Hohorst, L Bielicki, K Müller, G Voelcker J Cancer Res Clin Oncol 1988 new
Differential inhibition of various deoxyribonucleic acid polymerases by Evans blue and aurintricarboxylic acid. H Nakane, Jan Balzarini, Erik De Clercq, K Ono European journal of biochemistry / FEBS 1988 pols set
Fuchsin acid selectively inhibits human immunodeficiency virus (HIV) replication in vitro. Masanori Baba, Dominique Schols, Rudi Pauwels, Jan Balzarini, Erik De Clercq Biochemical and biophysical research communications 1988 pols set
Alpha, beta- and beta, gamma-methylene 5'-phosphonate derivatives of 3'-azido-2',3'-dideoxythymidine-5'-triphosphate. Correlation between affinity for reverse transcriptase, susceptibility to hydrolysis by phosphodiesterases and anti-retrovirus activity. Jan Balzarini, Piet Herdewijn, Rudi Pauwels, S Broder, Erik De Clercq Biochemical pharmacology 1988 new
Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro. Masanori Baba, Rudi Pauwels, Jan Balzarini, J Arnout, J Desmyter, Erik De Clercq Proceedings of the National Academy of Sciences of the United States of America 1988 pols set
Heterogeneity of HIV-1 replication and antigen expression in EBV-transformed B cell lines. M Tremblay, L Fitz-Gibbon, Mark A. Wainberg Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1988 pols set
Perspectives for the chemotherapy of AIDS. Erik De Clercq Chemioterapia : international journal of the Mediterranean Society of Chemotherapy 1988 pols set
Properties of the 3' to 5' exonuclease associated with calf DNA polymerase delta. R D Sabatino, Robert A Bambara Biochemistry 1988 new
Isolation of multiple forms of DNA polymerase delta: evidence of proteolytic modification during isolation. Marietta Y W T Lee Biochemistry 1988 new
A multisite-directed mutagenesis using T7 DNA polymerase: application for reconstructing a mammalian gene. T Z Su, M R el-Gewely Gene 1988 pols set
Infection of human monocytes/macrophages by HIV-1: effect on secretion of IL-1 activity. Sujit Roy, L Fitz-Gibbon, L Poulin, Mark A. Wainberg Immunology 1988 pols set
Cocrystal structure of an editing complex of Klenow fragment with DNA. P S Freemont, J M Friedman, Lorena S Beese, M R Sanderson, Thomas A Steitz Proceedings of the National Academy of Sciences of the United States of America 1988 complete
Characterization of DNA polymerase beta mRNA: cell-cycle and growth response in cultured human cells. B Z Zmudzka, A Fornace, J Collins, Samuel H Wilson Nucleic acids research 1988 new
Characterization of a photoaffinity analog of UTP, 5-azido-UTP for analysis of the substrate binding site on E. coli RNA polymerase. A Y Woody, R K Evans, R W Woody Biochemical and biophysical research communications 1988 topics set
Evidence for a reduction of the replicative activity of matrix-bound DNA polymerase alpha following treatment with phospholipase C. S Miscia, A Cataldi, A Ognibene, A M Martelli, L Manzoli, A M Billi, C De Marchis, L Cocco Cell Biol Int Rep 1988 new
Mouse DNA polymerase beta gene promoter: fine mapping and involvement of Sp1-like mouse transcription factor in its function. Masamitsu Yamaguchi, Y Hayashi, Akio Matsukage Nucleic acids research 1988 new
The dimer of the beta subunit of Escherichia coli DNA polymerase III holoenzyme is dissociated into monomers upon binding magnesium(II). Mark A Griep, Charles S McHenry Biochemistry 1988 pols set
[The activity of DNA polymerase in the blood of non-A, non-B hepatitis patients, and discussion on retrovirus as the causative agent]. Satoshi Watanabe, U Kano, S Shimamura, S Suzuki Nippon Rinsho 1988 new
Purification and characterization of DNA polymerase alpha from plasmodia of Physarum polycephalum. C Weber, H Fischer, Eggehard Holler Eur J Biochem 1988 new
Nucleotide excision by E. coli DNA polymerase I in proofreading and non-proofreading modes. P J Lecomte, J Ninio Biochimica et biophysica acta 1988 pols set
Fidelity of HIV-1 reverse transcriptase. Bradley D Preston, B J Poiesz, Lawrence A Loeb Science 1988 pols set
Purification and characterization of porcine liver DNA polymerase gamma: utilization of dUTP and dTTP during in vitro DNA synthesis. D W Mosbaugh Nucleic acids research 1988 new
Inhibitory activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine on the salmonid herpesviruses, Oncorhynchus masou virus (OMV) and Herpesvirus salmonis. T Kimura, T Nishizawa, M Yoshimizu, Erik De Clercq Microbiology and immunology 1988 new
Calf thymus DNA polymerase delta: purification, biochemical and functional properties of the enzyme after its separation from DNA polymerase alpha, a DNA dependent ATPase and proliferating cell nuclear antigen. Federico Focher, Silvio Spadari, B Ginelli, M Hottiger, M Gassmann, Ulrich Hübscher Nucleic acids research 1988 pols set
Mammalian cyclin/PCNA (DNA polymerase delta auxiliary protein) stimulates processive DNA synthesis by yeast DNA polymerase III. Peter M J Burgers Nucleic acids research 1988 new
Inhibition of varicella-zoster virus-induced DNA polymerase by a new guanosine analog, 9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine triphosphate. G Abele, B Eriksson, J Harmenberg, B Wahren Antimicrob Agents Chemother 1988 topics set
Site-directed mutagenesis in the DNA linking site of bacteriophage phi 29 terminal protein: isolation and characterization of a Ser232----Thr mutant. C Garmendia, Margarita Salas, José M Hermoso Nucleic acids research 1988 pols set
Effects of the Xenopus laevis mitochondrial single-stranded DNA-binding protein on the activity of DNA polymerase gamma. B Mignotte, J Marsault, M Barat-Gueride Eur J Biochem 1988 new
Slippage of DNA polymerase I during synthesis of ds-cDNA. R Devos, J Tavernier, W Fiers Nucleic acids research 1988 new
Thermostable DNA polymerase chain amplification of t(14;18) chromosome breakpoints and detection of minimal residual disease. M Crescenzi, M Seto, G P Herzig, P D Weiss, R C Griffith, S J Korsmeyer Proceedings of the National Academy of Sciences of the United States of America 1988 new
Comparison between DNA melting thermodynamics and DNA polymerase fidelity. John Petruska, Myron F Goodman, M S Boosalis, L C Sowers, C Cheong, I Tinoco Proceedings of the National Academy of Sciences of the United States of America 1988 new
Domain structure of the Moloney murine leukemia virus reverse transcriptase: mutational analysis and separate expression of the DNA polymerase and RNase H activities. N Tanese, S P Goff Proceedings of the National Academy of Sciences of the United States of America 1988 new
[The role of in vivo interaction of proteins SSB with DNA polymerase II]. G E Fradkin, E V Rabinkova, M V Torosian, O A Aĭzenberg, L A Naumova Mol Biol (Mosk) 1988 pols set
Positive and negative regulators for glucitol (gut) operon expression in Escherichia coli. Masami Yamada, M H Saier Journal of molecular biology 1988 new
Purification of nucleotide-linked peptide. V N Pandey, Mukund J Modak Journal of chromatography 1988 new
Substrate binding domain of murine leukemia virus reverse transcriptase. Identification of lysine 103 and lysine 421 as binding site residues. A Basu, V B Nanduri, G F Gerard, Mukund J Modak The Journal of biological chemistry 1988 new
DNA polymerase beta in human thyroid of Graves' disease and thyroid tumors. Akio Nagasaka, Shonen Yoshida, Akira Nakai, T Ohyama, K Iwase, Seiji Ohtani, S Shinoda, R Masunaga, H Nakagawa Metabolism 1988 new
Overproduction of the epsilon subunit of DNA polymerase III counteracts the SOS mutagenic response of Escherichia coli. Piotr Jonczyk, I Fijalkowska, Z Ciesla Proceedings of the National Academy of Sciences of the United States of America 1988 pols set
Bacteriophage T4 DNA polymerase determines the amount and specificity of ultraviolet mutagenesis. John W Drake Mol Gen Genet 1988 complete
Determination of the mutation rate of a retrovirus. J M Leider, P Palese, F I Smith J Virol 1988 new
Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerases. S W Wong, A F Wahl, P M Yuan, N Arai, B E Pearson, K Arai, D Korn, M W Hunkapiller, Teresa S-F Wang The EMBO journal 1988 partial results
Mechanism of stimulation of T7 DNA polymerase by Escherichia coli single-stranded DNA binding protein (SSB). T W Myers, Louis J Romano The Journal of biological chemistry 1988 pols set
Inhibition of HIV-1 RNA-dependent DNA polymerase and cellular DNA polymerases alpha, beta and gamma by phosphonoformic acid and other drugs. E M Wondrak, J Löwer, R Kurth J Antimicrob Chemother 1988 new
Characterization of DNA polymerase alpha activity from a mouse DNA temperature-sensitive mutant, strain tsFT20, which shows a defect in DNA polymerase alpha activity at restrictive temperatures. Toshihiko Eki, Takemi Enomoto, Y Murakami, Fumio Hanaoka, Masami Yamada Arch Biochem Biophys 1988 new
Effects of ganglioside GM1 on DNA synthesis in isolated nuclei and on the activity of DNA polymerase alpha derived from S-phase HeLa cells. T Ohsawa, H Ikeda, T Senshu Biochimica et biophysica acta 1988 new
DNA polymerase III holoenzyme of Escherichia coli. I. Purification and distinctive functions of subunits tau and gamma, the dnaZX gene products. Satoko Maki, Arthur Kornberg The Journal of biological chemistry 1988 pols set
DNA polymerase I gene of Saccharomyces cerevisiae: nucleotide sequence, mapping of a temperature-sensitive mutation, and protein homology with other DNA polymerases. A Pizzagalli, P Valsasnini, Paolo Plevani, G Lucchini Proceedings of the National Academy of Sciences of the United States of America 1988 topics set
Escherichia coli DnaX product, the tau subunit of DNA polymerase III, is a multifunctional protein with single-stranded DNA-dependent ATPase activity. Sang Hee Lee, J R Walker Proceedings of the National Academy of Sciences of the United States of America 1987 new
Response of isolated nuclei to phospholipid vesicles: effect of phosphatidylserine on alpha and beta DNA polymerase activity. L Cocco, S Miscia, A Cataldi, S Capitani, A Matteucci, A M Martelli, F A Manzoli Cell Biol Int Rep 1987 new
Biochemical characterization and development of DNA polymerases alpha and delta in the neonatal rat heart. S J Zhang, Marietta Y W T Lee Archives of biochemistry and biophysics 1987 new
O-Alkyl deoxythymidines are recognized by DNA polymerase I as deoxythymidine or deoxycytidine. B Singer, S J Spengler, F Chavez, J Sagi, J T Kúsmierek, Bradley D Preston, Lawrence A Loeb IARC Sci Publ 1987 topics set
Mutational specificity of a bacteriophage T4 DNA polymerase mutant, mel88. Linda J Reha-Krantz Mol Gen Genet 1987 topics set
Effect of NH4+ ions on phi 29 DNA-protein p3 replication: formation of a complex between the terminal protein and the DNA polymerase. Luis Blanco, I Prieto, J Gutiérrez, Antonio Bernad, José María Lázaro, José M Hermoso, Margarita Salas J Virol 1987 pols set
Expression of enzymatically active adenovirus DNA polymerase from cloned DNA requires sequences upstream of the main open reading frame. L M Shu, M S Horwitz, J A Engler Virology 1987 new
Exposure of HeLa DNA polymerase alpha to protein kinase C affects its catalytic properties. S W Krauss, D Mochly-Rosen, D E Koshland, Stuart Linn The Journal of biological chemistry 1987 new
Site-specific mutagenesis of AIDS virus reverse transcriptase. Brendan A Larder, D J Purifoy, K L Powell, G Darby Nature 1987 pols set
Macromolecular crowding increases binding of DNA polymerase to DNA: an adaptive effect. S B Zimmerman, B Harrison Proceedings of the National Academy of Sciences of the United States of America 1987 pols set
DNA polymerase insertion fidelity. Gel assay for site-specific kinetics. M S Boosalis, John Petruska, Myron F Goodman The Journal of biological chemistry 1987 partial results
Isolation of the DNA polymerase alpha core enzyme from mouse cells. C E Prussak, B Y Tseng The Journal of biological chemistry 1987 pols set
In vivo effects of mercury (II) on deoxyuridine triphosphate nucleotidohydrolase, DNA polymerase (alpha, beta), and uracil-DNA glycosylase activities in cultured human cells: relationship to DNA damage, DNA repair, and cytotoxicity. M V Williams, T Winters, K S Waddell Mol Pharmacol 1987 new
Photoaffinity labeling of the thymidine triphosphate binding domain in Escherichia coli DNA polymerase I: identification of histidine-881 as the site of cross-linking. V N Pandey, K R Williams, K L Stone, Mukund J Modak Biochemistry 1987 pols set
Inducible DNA polymerase I synthesis in a UV hyper-resistant mutant of Escherichia coli. S I Ahmad, C A van Sluis Mutation research 1987 pols set
Kinetic mechanism of DNA polymerase I (Klenow). Robert D Kuchta, V Mizrahi, P A Benkovic, Kenneth A Johnson, Stephen J Benkovic Biochemistry 1987 topics set
Construction of a DNA-polymerase I overproducing plasmid and isolation of the enzyme. K Bielawski, P Skowron, J Kur, G Konopa, A Podhajska, K Taylor Acta Biochim Pol 1987 new
Interaction between the DNA polymerase and single-stranded DNA-binding protein (infected cell protein 8) of herpes simplex virus 1. Mike E O'Donnell, P Elias, B E Funnell, I. Robert Lehman The Journal of biological chemistry 1987 new
Exonucleolytic proofreading by calf thymus DNA polymerase delta. Thomas A Kunkel, R D Sabatino, Robert A Bambara Proceedings of the National Academy of Sciences of the United States of America 1987 new
Identification of DNA polymerase delta in CV-1 cells: studies implicating both DNA polymerase delta and DNA polymerase alpha in DNA replication. R A Hammond, J J Byrnes, M R Miller Biochemistry 1987 new
Substrate specificity of DNA polymerases. II. 5-(1-Alkynyl)-dUTPs as substrates of the Klenow DNA polymerase enzyme. L Otvös, J Szécsi, J Sági, T Kovács Nucleic Acids Symp Ser 1987 new
[Effectiveness of complex-formation of nucleotides with human DNA polymerase alpha from data of enzyme modification by reactive nucleotide analogs]. G A Nevinskiĭ, S V Doronin, Vladimir N Podust, Olga I Lavrik Mol Biol (Mosk) 1987 pols set
Effect of morpholinyladriamycin analogs and adriamycin on the activities of DNA polymerase alpha and RNA polymerase II of chicken leukemia cells. L F Chuang, R Y Chuang, E M Acton, M Israel, M Yu J Pharmacol Exp Ther 1987 new
DNA polymerase activities in human placenta. A Ishii, H Hamada, M Takayanagi, Kiyoshi Hayashi Arch Gynecol Obstet 1987 new
Processing of concatemers of bacteriophage T7 DNA in vitro. J H White, Charles C Richardson The Journal of biological chemistry 1987 new
Probing DNA polymerase alpha with monoclonal antibodies. P Zahradka FEBS letters 1987 new
Mode of inhibition of the DNA polymerase of Methanococcus vannielii by aphidicolin. H P Zabel, Eggehard Holler, J Winter Eur J Biochem 1987 new
2',3'-Dideoxythymidine 5'-triphosphate inhibition of DNA replication and ultraviolet-induced DNA repair synthesis in human cells: evidence for involvement of DNA polymerase delta. S L Dresler, K S Kimbro Biochemistry 1987 new
Role of DNA polymerase I in postreplication repair: a reexamination with Escherichia coli delta polA. R C Sharma, K C Smith J Bacteriol 1987 new
Variation of incorporation of [3H]orotic acid into the nucleotide and RNA fractions of different parts of the same liver lobe in the rat. M Andersson, P I Christensson, L Lewan, U Stenram Int J Biochem 1987 topics set
Cyclin/PCNA is the auxiliary protein of DNA polymerase-delta. R Bravo, R Frank, P A Blundell, H Macdonald-Bravo Nature 1987 new
S1 plasmid from cms-S-maize mitochondria encodes a viral type DNA-polymerase. E V Kuzmin, I V Levchenko Nucleic acids research 1987 new
Aphidicolin-resistant mutator strains of mouse teratocarcinoma. S Aizawa, Lawrence A Loeb, G M Martin Molecular & general genetics : MGG 1987 new
First-strand cDNA synthesis primed with oligo(dT). M S Krug, S L Berger Methods in enzymology 1987 pols set
Replication of simian virus 40 origin-containing DNA in vitro with purified proteins. C R Wobbe, L Weissbach, J A Borowiec, F B Dean, Y Murakami, P Bullock, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1987 new
Monoclonal antibodies specific for the tau subunit of the DNA polymerase III holoenzyme of Escherichia coli. Use to demonstrate that tau is the product of the dnaZX gene and that both it and gamma, the dnaZ gene product, are integral components of the same enzyme assembly. J R Hawker, Charles S McHenry The Journal of biological chemistry 1987 pols set
Inhibition of herpesvirus-induced thymidine kinase and DNA polymerase by beta-hydroxynorvaline. M J Massare, H A Blough FEBS letters 1987 new
Enzymatic method for continuous monitoring of DNA polymerase activity. P Nyrén Anal Biochem 1987 new
Characterization of 2'(3')-trinitrophenyl-ATP as an inhibitor of ATP-dependent initiation complex formation between the DNA polymerase III holoenzyme and primed DNA. R Oberfelder, Charles S McHenry The Journal of biological chemistry 1987 pols set
[Eukaryotic and prokaryotic DNA-polymerase. II. The role of internucleotide phosphate groups of a template in its binding with the enzyme]. G A Nevinskiĭ, A S Levina, Vladimir N Podust, Olga I Lavrik Bioorg Khim 1987 new
Base substitution mutagenesis by terminal transferase: its role in somatic mutagenesis. E T Snow, Thomas A Kunkel, Lawrence A Loeb Mutation research 1987 new
Selective inhibition of DNA polymerase alpha by a polysaccharide purified from slime of Physarum polycephalum. M Shioda, K Murakami-Murofushi Biochem Biophys Res Commun 1987 new
[Inhibitory effect of various analogs of nucleoside-5'-triphosphates on DNA synthesis catalyzed by DNA polymerase from herpes simplex virus type I]. T Iu Kilesso, V M Shobukhov, A V Papchikhin, G A Galegov Mol Gen Mikrobiol Virusol 1987 new
Characterization of a stable, major DNA polymerase alpha species devoid of DNA primase activity. H B Kaiserman, R M Benbow Nucleic acids research 1987 new
Proofreading of a mutagenic nucleotide, N4-aminodeoxycytidylic acid, by Escherichia coli DNA polymerase I. Mayumi Takahashi, Kazuo Negishi, H Hayatsu Biochem Biophys Res Commun 1987 pols set
Phenotyping of proliferating lymphocytes in angioimmunoblastic lymphadenopathy and related lesions by the double immunoenzymatic staining technique. R Namikawa, T Suchi, R Ueda, G Itoh, K Koike, K Ota, T Takahashi The American journal of pathology 1987 pols set
Cyclin (PCNA, auxiliary protein of DNA polymerase delta) is a central component of the pathway(s) leading to DNA replication and cell division. J E Celis, P Madsen, A Celis, H V Nielsen, B Gesser FEBS letters 1987 pols set
Accessory proteins bind a primed template and mediate rapid cycling of DNA polymerase III holoenzyme from Escherichia coli. Mike E O'Donnell The Journal of biological chemistry 1987 pols set
Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. K B Mullis, F A Faloona Methods in enzymology 1987 topics set
Properties of initiation complexes formed between Escherichia coli DNA polymerase III holoenzyme and primed DNA in the absence of ATP. O Kwon-Shin, J B Bodner, Charles S McHenry, Robert A Bambara The Journal of biological chemistry 1987 pols set
Specificity and efficiency of editing of mismatches involved in the formation of base-substitution mutations by the 3'----5' exonuclease activity of phage T4 DNA polymerase. N K Sinha Proceedings of the National Academy of Sciences of the United States of America 1987 pols set
Long-term inhibition of human T-lymphotropic virus type III/lymphadenopathy-associated virus (human immunodeficiency virus) DNA synthesis and RNA expression in T cells protected by 2',3'-dideoxynucleosides in vitro. Hiroyuki Mitsuya, R F Jarrett, M Matsukura, F di Marzo Veronese, A L DeVico, M G Sarngadharan, D G Johns, M S Reitz, S Broder Proceedings of the National Academy of Sciences of the United States of America 1987 new
Multiple point mutations in a shuttle vector propagated in human cells: evidence for an error-prone DNA polymerase activity. M M Seidman, A Bredberg, S Seetharam, K H Kraemer Proceedings of the National Academy of Sciences of the United States of America 1987 new
Genetic relatedness of human DNA polymerase beta and terminal deoxynucleotidyltransferase. R S Anderson, C B Lawrence, Samuel H Wilson, K L Beattie Gene 1987 pols set
Purification and characterization of an inducible mitochondrial DNA polymerase from Tetrahymena thermophila. E Ostergaard, P Brams, O Westergaard, O F Nielsen Biochimica et biophysica acta 1987 new
[Age-dependent changes in the DNA-polymerase activity of nuclei and mitochondria of the regenerating rat liver]. E L Levitskiĭ, G I Davydova, A Ia Litoshenko Ukr Biokhim Zh 1987 new
Chemical modification of aphidicolin and the inhibitory effects of its derivatives on DNA polymerase alpha in vitro. S Hiranuma, Toshiyuki Shimizu, H Yoshioka, K Ono, H Nakane, Tomonori Takahashi Chem Pharm Bull (Tokyo) 1987 new
Immunological analysis of 140-kDa adenovirus-encoded DNA polymerase in adenovirus type 2-infected HeLa cells using antibodies raised against the protein expressed in Escherichia coli. Y Sasaguri, T Sanford, P Aguirre, R Padmanabhan Virology 1987 new
Main properties of duck hepatitis B virus DNA polymerase: comparison with the human and woodchuck hepatitis B virus DNA polymerases. I Fourel, O Hantz, L Cova, H S Allaudeen, C Trepo Antiviral Res 1987 new
Cloning and expression of T4 DNA polymerase. T C Lin, J Rush, E K Spicer, William H Konigsberg Proceedings of the National Academy of Sciences of the United States of America 1987 complete
Human placental DNA polymerase delta: identification of a 170-kilodalton polypeptide by activity staining and immunoblotting. Marietta Y W T Lee, N L Toomey Biochemistry 1987 pols set
Cellular transformation by adenovirus type 5 is influenced by the viral DNA polymerase. B W Miller, J Williams J Virol 1987 new
Base dynamics of nitroxide-labeled thymidine analogues incorporated into (dA-dT)n by DNA polymerase I from Escherichia coli. G T Pauly, I E Thomas, A M Bobst Biochemistry 1987 pols set
Selective oxidation of the exonuclease domain of bacteriophage T7 DNA polymerase. Stanley Tabor, Charles C Richardson The Journal of biological chemistry 1987 pols set
Monoclonal antibodies to alpha DNA polymerase as a marker of cell proliferative activity. A Alama, S Ferrini, M Gaddi, A Nicolin Int J Biol Markers 1987 new
In vitro replication of DNA containing either the SV40 or the polyoma origin. C R Wobbe, F B Dean, Y Murakami, J A Borowiec, P Bullock, Jerard Hurwitz Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1987 new
Structural studies of Klenow fragment: an enzyme with two active sites. Thomas A Steitz, L Beese, P S Freemont, J M Friedman, M R Sanderson Cold Spring Harbor symposia on quantitative biology 1987 pols set
Mammalian DNA polymerase alpha: a replication competent holoenzyme form from calf thymus. H Ottiger, P Frei, M Hässig, Ulrich Hübscher Nucleic acids research 1987 pols set
DNA polymerase-primase from embryos of Drosophila melanogaster. The DNA polymerase subunit. Sue Cotterill, G Chui, I. Robert Lehman The Journal of biological chemistry 1987 new
Nucleotide insertion kinetics opposite abasic lesions in DNA. S K Randall, R Eritja, B E Kaplan, John Petruska, Myron F Goodman The Journal of biological chemistry 1987 new
Apparent stimulation of calf thymus DNA polymerase alpha by ATP. Cheng-Keat Tan, M J So, Kathleen M Downey, Antero G So Nucleic acids research 1987 new
Functional identity of proliferating cell nuclear antigen and a DNA polymerase-delta auxiliary protein. G Prelich, Cheng-Keat Tan, M Kostura, M B Mathews, Antero G So, Kathleen M Downey, B Stillman Nature 1987 new
Evidence for a direct role of the DNA polymerase gamma in the replication of the human mitochondrial DNA in vitro. P Lestienne Biochem Biophys Res Commun 1987 pols set
Suramin in the treatment of AIDS: mechanism of action. Erik De Clercq Antiviral research 1987 new
Unwinding of duplex DNA from the SV40 origin of replication by T antigen. M Dodson, F B Dean, P Bullock, H Echols, Jerard Hurwitz Science (New York, N.Y.) 1987 new
Murine DNA polymerase beta gene: mapping of transcription initiation sites and the nucleotide sequence of the putative promoter region. Masamitsu Yamaguchi, Fumiko Hirose, Y Hayashi, Y Nishimoto, Akio Matsukage Molecular and cellular biology 1987 new
Effect of cycloheximide on heat-induced cell killing, radiosensitization, and loss of cellular DNA polymerase activities in Chinese hamster ovary cells. G L Chu, W C Dewey Radiat Res 1987 new
A cryptic proofreading 3'----5' exonuclease associated with the polymerase subunit of the DNA polymerase-primase from Drosophila melanogaster. S M Cotterill, M E Reyland, Lawrence A Loeb, I. Robert Lehman Proceedings of the National Academy of Sciences of the United States of America 1987 new
Synthesis of dihydrothymidine and thymidine glycol 5'-triphosphates and their ability to serve as substrates for Escherichia coli DNA polymerase I. Hiroshi Ide, R J Melamede, Susan S Wallace Biochemistry 1987 pols set
Phosphorylation of a high molecular weight DNA polymerase alpha. R W Donaldson, E W Gerner Proceedings of the National Academy of Sciences of the United States of America 1987 pols set
Evaluation of growth fractions with monoclonal antibodies to human alpha-DNA polymerase. A Alama, A Nicolin, P F Conte, B Drewinko Cancer research 1987 new
Preferential loss of DNA polymerase alpha following suppression of replicative DNA synthesis of guinea pig macrophages by the immunostimulants muramyl dipeptide or lipopolysaccharide. T Haraguchi, S Nagao, Akira Tanaka, H Nagano J Leukoc Biol 1987 new
Characterization of chromosome aberrations induced by incubation at a restrictive temperature in the mouse temperature-sensitive mutant tsFT20 strain containing heat-labile DNA polymerase alpha. Toshihiko Eki, Takemi Enomoto, Y Murakami, Fumio Hanaoka, Masami Yamada Cancer research 1987 new
Processive replication of single-stranded DNA templates by the herpes simplex virus-induced DNA polymerase. Mike E O'Donnell, P Elias, I. Robert Lehman The Journal of biological chemistry 1987 new
DNA sequence analysis with a modified bacteriophage T7 DNA polymerase. Stanley Tabor, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 1987 pols set
Reduction of DNA-polymerase beta activity of CHO cells by single and combined heat treatments. E Dikomey, W Becker, K Wielckens Int J Radiat Biol Relat Stud Phys Chem Med 1987 new
Ferrate oxidation of Escherichia coli DNA polymerase-I. Identification of a methionine residue that is essential for DNA binding. A Basu, K R Williams, Mukund J Modak The Journal of biological chemistry 1987 pols set
Induction of DNA polymerase alpha in isolated immature rat ovaries by follicle-stimulating hormone. S Usuki, M Shioda Horm Metab Res 1987 new
Incorporation of the carbocyclic analogue of (E)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate into a synthetic DNA. J Sági, Erik De Clercq, A Szemzö, A Csárnyi, T Kovács, L Otvös Biochemical and biophysical research communications 1987 new
Escherichia coli thioredoxin confers processivity on the DNA polymerase activity of the gene 5 protein of bacteriophage T7. Stanley Tabor, H E Huber, Charles C Richardson The Journal of biological chemistry 1987 partial results
Role of nucleoside components and internucleotide phosphate groups of oligodeoxyribonucleotide template in its binding to human DNA polymerase alpha. Olga I Lavrik, A S Levina, G A Nevinsky, Vladimir N Podust FEBS letters 1987 pols set
Mutagenic DNA repair in Escherichia coli. XIII. Proofreading exonuclease of DNA polymerase III holoenzyme is not operational during UV mutagenesis. Roger Woodgate, Bryn A Bridges, G Herrera, M Blanco Mutation research 1987 new
Identification and amino acid sequence of the deoxynucleoside triphosphate binding site in Escherichia coli DNA polymerase I. A Basu, Mukund J Modak Biochemistry 1987 pols set
[Prokaryotic and eukaryotic DNA-polymerase. I. The role of internucleotide phosphate groups in the binding of a primer with the enzyme]. G A Nevinskiĭ, E I Frolova, A S Levina, Vladimir N Podust, A V Lebedev Bioorg Khim 1987 new
An endogenous protein inhibitor of DNA polymerase alpha in normal and neoplastic rat mammary tissues. C M Klinge, D K Liu Int J Biochem 1987 new
Inhibition of repair of X-ray-induced DNA damage by heat: the role of hyperthermic inhibition of DNA polymerase alpha activity. H H Kampinga, A W Konings Radiat Res 1987 new
In vitro initiation of DNA replication in simian virus 40 chromosomes. R S Decker, Masamitsu Yamaguchi, R Possenti, M K Bradley, M L DePamphilis The Journal of biological chemistry 1987 new
Inhibition of DNA polymerase-alpha by ara-CMP in the presence of a regulatory protein extracted from human promyelocytic leukemic cells (HL-60). J M Leclerc, L Grisé-Miron, L Labonté Semin Oncol 1987 new
Some aspects of DNA polymerase functioning. A A Krayevsky, M K Kukhanova, R Sh Beabealashvilli, Z G Chidgeavadze Nucleic Acids Symp Ser 1987 new
The efficiency of dNTP complex formation with human placenta DNA polymerase alpha as demonstrated by affinity modification. S V Doronin, Olga I Lavrik, G A Nevinsky, Vladimir N Podust FEBS letters 1987 new
Biosynthesis and activity of DNA polymerase throughout the mitotic cycle of Physarum polycephalum. A M MacNicol, G R Banks, R A Cox FEBS letters 1987 new
DNA polymerase III of Escherichia coli is required for UV and ethyl methanesulfonate mutagenesis. M E Hagensee, T L Timme, S K Bryan, Robb E Moses Proceedings of the National Academy of Sciences of the United States of America 1987 pols set
Double immunoenzymatic detection of surface phenotype of proliferating lymphocytes in situ with monoclonal antibodies against DNA polymerase alpha and lymphocyte membrane antigens. R Namikawa, R Ueda, T Suchi, G Itoh, K Ota, T Takahashi American journal of clinical pathology 1987 pols set
Protection of oligonucleotide primers against degradation by DNA polymerase I. J Ott, F Eckstein Biochemistry 1987 pols set
On the fidelity of DNA replication: herpes DNA polymerase and its associated exonuclease. J Abbotts, Yoshitaka Nishiyama, Shonen Yoshida, Lawrence A Loeb Nucleic acids research 1987 new
Identification of 100 and 150 S DNA polymerase alpha-primase megacomplexes solubilized from the nuclear matrix of regenerating rat liver. R A Tubo, R Berezney The Journal of biological chemistry 1987 new
Structural and functional relationships between prokaryotic and eukaryotic DNA polymerases. Antonio Bernad, A Zaballos, Margarita Salas, Luis Blanco The EMBO journal 1987 new
Proofreading by DNA polymerase III of Escherichia coli depends on cooperative interaction of the polymerase and exonuclease subunits. Hisaji Maki, Arthur Kornberg Proceedings of the National Academy of Sciences of the United States of America 1987 pols set
DNA polymerase-primase from embryos of Drosophila melanogaster. DNA primase subunits. Sue Cotterill, G Chui, I. Robert Lehman The Journal of biological chemistry 1987 new
Genetics and biochemical studies of the bacteriophage T4 DNA polymerase Book: DNA Replication and Recombination 1987 complete
Phosphorylation of nucleoside analogs by equine herpesvirus type 1 pyrimidine deoxyribonucleoside kinase. S Kit, H Ichimura, Erik De Clercq Antiviral research 1987 new
The DNA sequence specificity of stimulation of DNA polymerases by factor D. M Fry, R Sharf, P Weisman-Shomer, P C Evers, Lawrence A Loeb The Journal of biological chemistry 1987 new
Sequence analysis of the Escherichia coli dnaE gene. H G Tomasiewicz, Charles S McHenry Journal of bacteriology 1987 new
p53 and DNA polymerase alpha compete for binding to SV40 T antigen. J V Gannon, D P Lane Nature 1987 new
DNA polymerase III requirement for repair of DNA damage caused by methyl methanesulfonate and hydrogen peroxide. M E Hagensee, S K Bryan, Robb E Moses J Bacteriol 1987 new
Inhibition of hepatitis B virus DNA polymerase by 3'-azido-3'-deoxythymidine triphosphate but not by its threo analog. E Nordenfelt, B Löfgren, J Chattopadhyaya, Bo Oberg J Med Virol 1987 topics set
Association of Epstein-Barr virus early antigen diffuse component and virus-specified DNA polymerase activity. J S Li, B S Zhou, Ginger E Dutschman, Susan P Grill, R S Tan, Yung-Chi Cheng J Virol 1987 pols set
Lability of DNA polymerase alpha correlated with decreased DNA synthesis and increased age in human cells. D Busbee, V Sylvia, J Stec, Z Cernosek, J Norman J Natl Cancer Inst 1987 new
[Serological and immunomolecular markers for the diagnosis of hematopoietic tumors]. R Ueda, Y Obata, T Takahashi Gan to kagaku ryoho. Cancer & chemotherapy 1987 new
Betalactam antibiotics interfere with eukaryotic DNA-replication by inhibiting DNA polymerase alpha. U H Do, K A Neftel, Silvio Spadari, Ulrich Hübscher Nucleic acids research 1987 new
ATP-stimulated polymerase activity involving DNA polymerase I and a recB-dependent factor in extracts of Escherichia coli cells. Juhani E Syväoja Acta Chem Scand B 1987 pols set
Specific immune serum to the Epstein-Barr virus DNA polymerase. R G Petit, K Leung, J E Shaw J Virol 1987 new
Stimulation of purified DNA polymerase alpha by various basic proteins which interact with activated DNA. T Hironaka, A Itaya, K Yoshihara, T Minaga, T Kamiya Anal Biochem 1987 new
Homology between mammalian DNA polymerase beta and terminal deoxynucleotidyltransferase. Akio Matsukage, K Nishikawa, T Ooi, Y Seto, Masamitsu Yamaguchi The Journal of biological chemistry 1987 pols set
DNA polymerase A and its stimulative factor of baker's yeast: purification and characterization. N Takizawa, H Saitoh, Y Kihira, K Miyazaki, T Kakuno, J Yamashita, T Horio J Biochem 1987 new
Novel blunt-end addition reactions catalyzed by DNA polymerase I of Escherichia coli. J M Clark, Catherine M Joyce, G P Beardsley Journal of molecular biology 1987 pols set
Chromosomal location of the human gene for DNA polymerase beta. O W McBride, B Z Zmudzka, Samuel H Wilson Proceedings of the National Academy of Sciences of the United States of America 1987 new
Dynamics of termination during in vitro replication of ultraviolet-irradiated DNA with DNA polymerase III holoenzyme of Escherichia coli. H Shwartz, Zvi Livneh The Journal of biological chemistry 1987 pols set
Mammalian DNA polymerase alpha: a replication-competent holoenzyme form from calf thymus. Ulrich Hübscher, M Gassmann, Silvio Spadari, Neal C Brown, Elena Ferrari, H J Buhk Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1987 pols set
On the fidelity of DNA replication. Isolation of high fidelity DNA polymerase-primase complexes by immunoaffinity chromatography. M E Reyland, Lawrence A Loeb The Journal of biological chemistry 1987 new
Expression and processing of the AIDS virus reverse transcriptase in Escherichia coli. W G Farmerie, D D Loeb, N C Casavant, C A Hutchison, M H Edgell, R Swanstrom Science 1987 new
Enhanced processivity of nuclear matrix bound DNA polymerase alpha from regenerating rat liver. R A Tubo, A M Martelli, R Berezney Biochemistry 1987 new
A DNA polymerase with unusual properties from the slime mold Physarum polycephalum. Eggehard Holler, H Fischer, C Weber, H Stopper, H Steger, H Simek Eur J Biochem 1987 new
The ability of DNA polymerase beta to synthesize DNA beyond the gap with displacement of the non-replicated strand. Radosława Nowak, J Kulik, Janusz A Siedlecki Acta Biochim Pol 1987 new
Escherichia coli thioredoxin stabilizes complexes of bacteriophage T7 DNA polymerase and primed templates. H E Huber, Stanley Tabor, Charles C Richardson The Journal of biological chemistry 1987 pols set
Current understanding of UV-induced base pair substitution mutation in E. coli with particular reference to the DNA polymerase III complex. Bryn A Bridges, Roger Woodgate, M Ruiz-Rubio, F Sharif, S G Sedgwick, Ulrich Hübscher Mutation research 1987 new
Inhibitory effect of glycyrrhizin on the in vitro infectivity and cytopathic activity of the human immunodeficiency virus [HIV (HTLV-III/LAV)]. M Ito, H Nakashima, Masanori Baba, Rudi Pauwels, Erik De Clercq, S Shigeta, N Yamamoto Antiviral research 1987 pols set
Immunoaffinity-purified DNA polymerase alpha displays novel properties. Heinz Peter Nasheuer, Frank Grosse Biochemistry 1987 new
DNA functional groups required for formation of open complexes between Escherichia coli RNA polymerase and the lambda PR promoter. Identification via base analog substitutions. J W Dubendorff, P L deHaseth, M S Rosendahl, M H Caruthers The Journal of biological chemistry 1987 topics set
Characterization of revertants derived from a mouse DNA temperature-sensitive mutant strain, tsFT20, which contains heat-labile DNA polymerase alpha activity. Toshihiko Eki, Takemi Enomoto, Y Murakami, Hiroshi Miyazawa, Fumio Hanaoka, Masami Yamada Exp Cell Res 1987 new
The beta subunit dissociates readily from the Escherichia coli DNA polymerase III holoenzyme. R S Lasken, Arthur Kornberg The Journal of biological chemistry 1987 pols set
Bacteriophage T4 DNA primase-helicase. Characterization of the DNA synthesis primed by T4 61 protein in the absence of T4 41 protein. Nancy G Nossal, D M Hinton The Journal of biological chemistry 1987 complete
Effect of prolactin, progesterone, pregnancy and lactation on DNA synthesis and DNA polymerase activities in rabbit mammary gland. L Zwierzchowski, W Niedbalski, D Kleczkowska J Endocrinol 1987 new
Differential effect of ARA-AMP on serum DNA polymerase activity and serum HBV-DNA in chronic hepatitis B virus infection. A possible reason for lack of efficacy. G J Alexander, E A Fagan, N Rolando, P Guarner, M E Callender, A L Eddleston, R Williams J Hepatol 1986 new
Identification of a DNA segment containing the human DNA polymerase alpha gene. Hiroshi Miyazawa, M Tandai, Fumio Hanaoka, Masami Yamada, T Hori, Kikuo Shimizu, M Sekiguchi Biochemical and biophysical research communications 1986 pols set
Sequence dependence for bypass of thymine glycols in DNA by DNA polymerase I. R C Hayes, J E LeClerc Nucleic acids research 1986 pols set
Selection of template initiation sites and the lengths of RNA primers synthesized by DNA primase are strongly affected by its organization in a multiprotein DNA polymerase alpha complex. J K Vishwanatha, Masamitsu Yamaguchi, M L DePamphilis, E F Baril Nucleic acids research 1986 new
Synthesis and properties of defined DNA oligomers containing base mispairs involving 2-aminopurine. R Eritja, B E Kaplan, D Mhaskar, L C Sowers, John Petruska, Myron F Goodman Nucleic acids research 1986 new
Mapping transcription start points on cloned genomic DNA with T4 DNA polymerase: a precise and convenient technique. M C Hu, N Davidson Gene 1986 pols set
Pathogenicity of herpes simplex virus mutants containing drug resistance mutations in the viral DNA polymerase gene. H J Field, Donald M Coen Journal of virology 1986 new
DNA polymerase activity in the n.hexadecane-induced hyperkeratotic epidermis. R Ogura, N Kaneko, T Hidaka Arch Dermatol Res 1986 new
Properties of two forms of DNA polymerase delta from calf thymus. A F Wahl, J J Crute, R D Sabatino, J B Bodner, R L Marraccino, L W Harwell, E M Lord, Robert A Bambara Biochemistry 1986 pols set
Production of antibody-tagged enzymes by myeloma cells: application to DNA polymerase I Klenow fragment. G T Williams, M S Neuberger Gene 1986 pols set
The beta subunit of the Escherichia coli DNA polymerase III holoenzyme interacts functionally with the catalytic core in the absence of other subunits. R J LaDuca, J J Crute, Charles S McHenry, Robert A Bambara The Journal of biological chemistry 1986 pols set
Interaction of DNA polymerase III gamma and beta subunits in vivo in Salmonella typhimurium. J Engstrom, A Wong, R Maurer Genetics 1986 new
Differentiation of lens and neural cells in chicken embryos is accompanied by simultaneous decay of DNA replication machinery. Akio Matsukage, H Kitani, Masamitsu Yamaguchi, M Kusakabe, T Morita, Y Koshida Developmental biology 1986 new
Persistence of DNA synthesis arrest sites in the presence of T4 DNA polymerase and T4 gene 32, 44, 45 and 62 DNA polymerase accessory proteins. M F Charette, D T Weaver, M L DePamphilis Nucleic acids research 1986 pols set
Cloning a defined region of DNA using a limited action of DNA polymerase: application to dissection of hepatitis B virus surface antigen gene. O Chisaka, Shigenori Iwai, E Ohtsuka, Kiminori Matsubara Gene 1986 pols set
Incidence of hepatitis B virus DNA and DNA-polymerase in sera of Italian asymptomatic carriers with the serological markers of HBV. G Carloni, C Delfini, S Colloca, E Alfani, G Taliani, C De Bac Arch Virol 1986 new
A microinjected monoclonal antibody against human DNA polymerase-alpha inhibits DNA replication in human, hamster, and mouse cell lines. L Kaczmarek, M R Miller, R A Hammond, W E Mercer The Journal of biological chemistry 1986 pols set
Synthesis of DNA polymerase alpha analyzed by immunoprecipitation from synchronously proliferating cells. P Thömmes, T Reiter, R Knippers Biochemistry 1986 new
Sequence of human DNA polymerase beta mRNA obtained through cDNA cloning. Dibyendu Narayan SenGupta, B Z Zmudzka, P Kumar, F Cobianchi, J Skowronski, Samuel H Wilson Biochemical and biophysical research communications 1986 pols set
Characterization of 3'----5' exonuclease associated with DNA polymerase of silkworm nuclear polyhedrosis virus. V S Mikhailov, K A Marlyev, J O Ataeva, P K Kullyev, A M Atrazhev Nucleic acids research 1986 new
Contrasting effects of Escherichia coli single-stranded DNA binding protein on synthesis by T7 DNA polymerase and Escherichia coli DNA polymerase I (large fragment). Evidence that binding protein inhibits trans-lesion synthesis by polymerase I. M L Michaels, M S Lee, Louis J Romano The Journal of biological chemistry 1986 pols set
DNA replication and UV-induced DNA repair synthesis in human fibroblasts are much less sensitive than DNA polymerase alpha to inhibition by butylphenyl-deoxyguanosine triphosphate. S L Dresler, M G Frattini Nucleic acids research 1986 new
Levels of topoisomerase II and DNA polymerase alpha are regulated independently in developing neuronal nuclei. K Tsutsui, K Tsutsui, H Sakurai, T Shohmori, T Oda Biochem Biophys Res Commun 1986 new
Species-specific in vitro synthesis of DNA containing the polyoma virus origin of replication. Y Murakami, Toshihiko Eki, Masami Yamada, C Prives, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1986 new
Cloning and expression of a cDNA encoding a catalytically active fragment of calf thymus DNA polymerase alpha. K Foster, K Lüthi-Steinmann, M Barnes, G McMaster, Elena Ferrari, K Eliassen, N Khan, N Brown, Ulrich Hübscher Biochemical and biophysical research communications 1986 new
Frameshift mutagenesis by eucaryotic DNA polymerases in vitro. Thomas A Kunkel The Journal of biological chemistry 1986 new
Epstein-Barr virus-specific DNA polymerase in virus-nonproducer Raji cells. T Ooka, G M Lenoir, G Decaussin, G W Bornkamm, J Daillie J Virol 1986 new
Mutagenesis in vitro by DNA polymerases alpha, beta and gamma. Thomas A Kunkel, P S Alexander, J C Liu, J M Fox Progress in clinical and biological research 1986 new
Recognition of sugar moieties on substrate analogues by DNA polymerase alpha 2-primase from developing cherry salmon (Oncorhynchus masou) testes. Shunji Izuta, Seisuke Kimura, K Takenuki, Mineo Saneyoshi Nucleic Acids Symp Ser 1986 new
Poly(ADP-ribosyl)ation of DNA polymerase beta in vitro. Y Ohashi, A Itaya, Y Tanaka, K Yoshihara, T Kamiya, Akio Matsukage Biochem Biophys Res Commun 1986 new
Demonstration of Epstein-Barr virus-specific DNA polymerase in chemically induced Raji cells and its antibody in serum from patients with nasopharyngeal carcinoma. R S Tan, J S Li, Susan P Grill, L M Nutter, Yung-Chi Cheng Cancer research 1986 pols set
Glycosylation inhibitors block the expression of LAV/HTLV-III (HIV) glycoproteins. H A Blough, Rudi Pauwels, Erik De Clercq, J Cogniaux, S Sprecher-Goldberger, L Thiry Biochemical and biophysical research communications 1986 pols set
Increase in DNA polymerase alpha activity associated with DNA synthesis due to FSH or oestrogen in ovaries of immature rats. S Usuki, M Shioda J Endocrinol 1986 new
Isolation of the nuclear gene encoding a subunit of the yeast mitochondrial RNA polymerase. JL Kelly, AL Greenleaf, I. Robert Lehman The Journal of biological chemistry 1986 new
Effects of suramin on in vitro HBsAg production by PLC/PRF/5 cells and hepatitis B virus DNA polymerase activity. H A Kessler, J C Pottage, G M Trenholme, C A Benson, S Levin AIDS Res 1986 new
Yeast mitochondrial RNA polymerase. Purification and properties of the catalytic subunit. JL Kelly, I. Robert Lehman The Journal of biological chemistry 1986 new
Detection and characterization of a novel factor that stimulates DNA polymerase alpha. K Kawasaki, Takemi Enomoto, Motoshi Suzuki, Masayuki Seki, Fumio Hanaoka, Masami Yamada Biochemistry 1986 new
Aurintricarboxylic acid and Evans Blue represent two different classes of anionic compounds which selectively inhibit the cytopathogenicity of human T-cell lymphotropic virus type III/lymphadenopathy-associated virus. Jan Balzarini, Hiroyuki Mitsuya, Erik De Clercq, S Broder Biochemical and biophysical research communications 1986 new
A DNA binding protein specific for an origin of replication of herpes simplex virus type 1. P Elias, ME O'Donnell, ES Mocarski, I. Robert Lehman Proceedings of the National Academy of Sciences of the United States of America 1986 new
Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome. AL Greenleaf, JL Kelly, I. Robert Lehman Proceedings of the National Academy of Sciences of the United States of America 1986 new
A mitochondrial DNA polymerase from embryos of Drosophila melanogaster. Purification, subunit structure, and partial characterization. C M Wernette, Laurie S Kaguni The Journal of biological chemistry 1986 new
Characterization of the DNA of the hamster papovavirus: IV. Transcription mapping of calf-thymus DNA polymerase II. F Vogel, S Scherneck Arch Geschwulstforsch 1986 new
Cloning of a gene encoding a DNA polymerase-exonuclease of Streptococcus pneumoniae. S Martinez, P Lopez, M Espinosa, S A Lacks Gene 1986 new
Thymine glycol lesions terminate chain elongation by DNA polymerase I in vitro. J M Clark, G P Beardsley Nucleic acids research 1986 pols set
The influence of a protein synthesis inhibitor on sister-chromatid exchange in the plant Vicia faba. A Sono, Kengo Sakaguchi Mutation research 1986 new
Mutagenic potential of O4-methylthymine in vivo determined by an enzymatic approach to site-specific mutagenesis. Bradley D Preston, B Singer, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1986 pols set
Signals in the phi 29 DNA-terminal protein template for the initiation of phage phi 29 DNA replication. J Gutiérrez, J Vinós, I Prieto, E Méndez, José M Hermoso, Margarita Salas Virology 1986 pols set
Purification and characterization of two new high molecular weight forms of DNA polymerase delta. J J Crute, A F Wahl, Robert A Bambara Biochemistry 1986 new
Assignment of the gene for human DNA polymerase beta (POLB) to chromosome 8. Akio Matsukage, Masamitsu Yamaguchi, K R Utsumi, Y Hayashi, R Ueda, M C Yoshida Japanese journal of cancer research : Gann 1986 pols set
Functional implications of the Klenow fragment structure. Thomas A Steitz, P S Freemont, David L Ollis, Catherine M Joyce, J M Grindley Biochem Soc Trans 1986 pols set
Phosphatidylinositol-dependent activation of DNA polymerase alpha. V L Sylvia, C O Joe, J O Norman, G M Curtin, David L Busbee Biochem Biophys Res Commun 1986 new
Characterization of DNA primase separated from DNA polymerase alpha-DNA primase complex of calf thymus. R Suzuki, S Masaki, Osamu Koiwai, Shonen Yoshida J Biochem 1986 new
Mutations induced by DNA polymerase alpha upon in vitro replication of M13mp8(+) DNA. B Reckmann, Gerhard Krauss Nucleic acids research 1986 new
Activity levels of mouse DNA polymerase alpha-primase complex (DNA replicase) and DNA polymerase alpha, free from primase activity in synchronized cells, and a comparison of their catalytic properties. T Kozu, T Seno, T Yagura Eur J Biochem 1986 new
DNA polymerase alpha associated primase from rat liver: physiological variations. Magali Philippe, J M Rossignol, A M de Recondo Biochemistry 1986 new
Effect of aphidicolin and nucleotide analogs on the phage phi 29 DNA polymerase. Luis Blanco, Margarita Salas Virology 1986 pols set
Incorporation of nucleotide tracers into nucleic acids in permeabilized cells and cellular homogenates. K Pawlak, C Lawi-Berger, W Sadée Biochem J 1986 topics set
NMR studies of conformations and interactions of substrates and ribonucleotide templates bound to the large fragment of DNA polymerase I. L J Ferrin, A S Mildvan Biochemistry 1986 new
Frameshift mutations produced by proflavin in bacteriophage T4: specificity within a hotspot. L S Ripley, A Clark Proceedings of the National Academy of Sciences of the United States of America 1986 topics set
Promoters selected from random DNA sequences. M S Horwitz, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1986 new
Effect of 4-quinolones and novobiocin on calf thymus DNA polymerase alpha primase complex, topoisomerases I and II, and growth of mammalian lymphoblasts. P Hussy, G Maass, B Tümmler, Frank Grosse, U Schomburg Antimicrob Agents Chemother 1986 new
Rearrangements of DNA mediated by terminal transferase. Thomas A Kunkel, K P Gopinathan, D K Dube, E T Snow, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1986 new
Purification and properties of chloroplast DNA polymerase. K K Tewari Methods in enzymology 1986 new
Studies on DNA polymerases of Xenopus laevis oocytes: subcellular distribution and physical association of DNA polymerase alpha inside the nucleus. A Solari, L Zourgui, P Carvallo, L Tarrago-Litvak Biol Cell 1986 new
Replication of phage phi 29 DNA in vitro: role of the viral protein p6 in initiation and elongation. Luis Blanco, J Gutiérrez, José María Lázaro, Antonio Bernad, Margarita Salas Nucleic acids research 1986 new
A cell-cycle-dependent DNA polymerase activity that replicates intact DNA in chromatin. D A Jackson, P R Cook Journal of molecular biology 1986 new
Aphidicolin-resistant mutants of bacteriophage phi 29: genetic evidence for altered DNA polymerase. K Matsumoto, C I Kim, S Urano, Mochihiko Ohashi, H Hirokawa Virology 1986 new
Structural organization and unusual codon usage in the DNA polymerase gene from herpes simplex virus type 1. J D Hall, J S Gibbs, Donald M Coen, D W Mount DNA (Mary Ann Liebert, Inc.) 1986 new
Yeast DNA primase and DNA polymerase activities. An analysis of RNA priming and its coupling to DNA synthesis. H Singh, R G Brooke, M H Pausch, G T Williams, C Trainor, L B Dumas The Journal of biological chemistry 1986 new
Replication of UV-irradiated single-stranded DNA by DNA polymerase III holoenzyme of Escherichia coli: evidence for bypass of pyrimidine photodimers. Z Livneh Proceedings of the National Academy of Sciences of the United States of America 1986 pols set
Mechanism of replication of ultraviolet-irradiated single-stranded DNA by DNA polymerase III holoenzyme of Escherichia coli. Implications for SOS mutagenesis. Zvi Livneh The Journal of biological chemistry 1986 pols set
Mutation within the herpes simplex virus DNA polymerase gene conferring resistance to (R)-9-(3,4-dihydroxybutyl)guanine. H C Chiou, K M Kerns, Donald M Coen Antimicrob Agents Chemother 1986 new
Mnemonic aspects of Escherichia coli DNA polymerase I. Interaction with one template influences the next interaction with another template. C Papanicolaou, P Lecomte, J Ninio Journal of molecular biology 1986 pols set
Different populations of DNA polymerase alpha in HeLa cells. D A Jackson, P R Cook Journal of molecular biology 1986 new
Characterization of DNA replication at a restrictive temperature in a mouse DNA temperature-sensitive mutant, tsFT20 strain, containing heat-labile DNA polymerase alpha activity. Toshihiko Eki, Y Murakami, Takemi Enomoto, Fumio Hanaoka, Masami Yamada The Journal of biological chemistry 1986 new
Inhibition of herpes simplex virus-induced DNA polymerases and cellular DNA polymerase alpha by triphosphates of acyclic guanosine analogs. A Larsson, A Sundqvist, A M Parnerud Mol Pharmacol 1986 new
[DNA-polymerase alpha from human placenta. Effectiveness of interaction between oligothymidylates of different lengths and the template-binding site]. G A Nevinskiĭ, Vladimir N Podust, A S Levina, O V Khalabuda, Olga I Lavrik Bioorg Khim 1986 new
Mechanism of DNA polymerase I: exonuclease/polymerase activity switch and DNA sequence dependence of pyrophosphorolysis and misincorporation reactions. V Mizrahi, P Benkovic, Stephen J Benkovic Proceedings of the National Academy of Sciences of the United States of America 1986 pols set
[Non-canonical nucleotide exchange catalyzed by Escherichia coli DNA-polymerase I and the two-center model of the mechanism of action of this enzyme]. Z G Chidzhavadze, R Sh Bibilashvili, A A Kraevskiĭ Mol Biol (Mosk) 1986 pols set
Intranuclear dynamics of DNA polymerase alpha differs between the transplanted R3230AC mammary adenocarcinomas and the host mammary gland depending on lactation cycle. C M Klinge, D K Liu Biochimica et biophysica acta 1986 new
Formation of a covalent complex between the terminal protein of pneumococcal bacteriophage Cp-1 and 5'-dAMP. P García, José M Hermoso, J A García, E García, R López, Margarita Salas J Virol 1986 pols set
[Activity of DNA polymerase alpha in acute leukemia: comparative analysis of the catalytic unit of the enzyme based on SDS polyacrylamide electrophoresis]. F Lori, C Casoli, R Starcich Boll Soc Ital Biol Sper 1986 new
Inhibition of DNA polymerase activity by methyl methanesulfonate. J O Norman, C O Joe, David L Busbee Mutation research 1986 new
Inhibitors of Bacillus subtilis DNA polymerase III. Influence of modifications in the pyrimidine ring of anilino- and (benzylamino)pyrimidines. D J Trantolo, George E Wright, Neal C Brown J Med Chem 1986 pols set
Mechanism of initiation of in vitro DNA synthesis by the immunopurified complex between yeast DNA polymerase I and DNA primase. G Badaracco, P Valsasnini, Marco Foiani, R Benfante, G Lucchini, Paolo Plevani Eur J Biochem 1986 new
Further characterization of a murine temperature-sensitive mutant, tsFT20 strain, containing heat-labile DNA polymerase alpha-activity. Y Murakami, Toshihiko Eki, Hiroshi Miyazawa, Takemi Enomoto, Fumio Hanaoka, Masami Yamada Exp Cell Res 1986 new
A domain of the Klenow fragment of Escherichia coli DNA polymerase I has polymerase but no exonuclease activity. P S Freemont, David L Ollis, Thomas A Steitz, Catherine M Joyce Proteins 1986 pols set
Enucleation of human endometrial cells: nucleo-cytoplasmic distribution of DNA polymerase alpha and estrogen receptor. A Gravanis, E Gurpide J Steroid Biochem 1986 new
Molecular biology of terminal transferase. L M Chang, F J Bollum CRC Crit Rev Biochem 1986 partial results
The bacteriophage T4 DNA polymerase: a model system for studies of the biochemical basis of spontaneous mutation and for studies of DNA polymerase structure-function relationships The Genetics Society of Canada Bulletin 1986 complete
Hepatitis B virus associated DNA polymerase inactivation in factor IX concentrates. G Mitra, P K Ng Thromb Res 1986 new
A new DNA-dependent ATPase which stimulates yeast DNA polymerase I and has DNA-unwinding activity. Akio Sugino, B H Ryu, T Sugino, L Naumovski, Errol C Friedberg The Journal of biological chemistry 1986 new
DNA synthesis in vitro with an endoplasmic-reticulum-DNA-polymerase complex from unfertilized sea urchin eggs. M Shioda Eur J Biochem 1986 new
Inhibition of human DNA polymerase alpha by alpha 1-antichymotrypsin. M Tsuda, M Masuyama, T Katsunuma Cancer research 1986 pols set
Alteration of the exonuclease activities of DNA polymerase I by captan. M J Freeman-Wittig, R A Lewis Biochimica et biophysica acta 1986 new
An RNA polymerase mutant with reduced accuracy of chain elongation. A Blank, J A Gallant, R R Burgess, Lawrence A Loeb Biochemistry 1986 new
[DNA polymerase alpha]. Masami Yamada Tanpakushitsu Kakusan Koso 1986 new
T-antigen-DNA polymerase alpha complex implicated in simian virus 40 DNA replication. S T Smale, R Tjian Molecular and cellular biology 1986 new
Characterization of highly immunogenic p66/p51 as the reverse transcriptase of HTLV-III/LAV. F di Marzo Veronese, T D Copeland, A L DeVico, R Rahman, S Oroszlan, R C Gallo, M G Sarngadharan Science 1986 pols set
Isolation of bacteriophage T4 DNA polymerase mutator mutants. Linda J Reha-Krantz, E M Liesner, S Parmaksizoglu, S Stocki Journal of molecular biology 1986 complete
Recognition of B and Z forms of DNA by Escherichia coli DNA polymerase I. N Ramesh, Y S Shouche, S K Brahmachari Journal of molecular biology 1986 pols set
[Demonstration of the heterogeneity of DNA polymerase alpha in embryonal tissues with high proliferative activity: structural analysis of the subunit in the human fetal liver]. C Casoli, F Lori, R Starcich Boll Soc Ital Biol Sper 1986 new
Differential effects of dimethylsulfoxide on the activities of human DNA polymerases alpha and delta. Marietta Y W T Lee, N L Toomey Nucleic acids research 1986 pols set
An auxiliary protein for DNA polymerase-delta from fetal calf thymus. Cheng-Keat Tan, C Castillo, Antero G So, Kathleen M Downey The Journal of biological chemistry 1986 topics set
Monoclonal antibody that blocks phosphoinositide-dependent activation of mouse tumor DNA polymerase alpha. V L Sylvia, J O Norman, G M Curtin, David L Busbee Biochem Biophys Res Commun 1986 new
Structure of rat DNA polymerase beta revealed by partial amino acid sequencing and cDNA cloning. B Z Zmudzka, D SenGupta, Akio Matsukage, F Cobianchi, P Kumar, Samuel H Wilson Proceedings of the National Academy of Sciences of the United States of America 1986 new
Spectrum of spontaneous frameshift mutations. Sequences of bacteriophage T4 rII gene frameshifts. L S Ripley, A Clark, J G deBoer Journal of molecular biology 1986 complete
DNA polymerase activity in heat killing and hyperthermic radiosensitization of mammalian cells as observed after fractionated heat treatments. J B Jorritsma, P Burgman, H H Kampinga, A W Konings Radiat Res 1986 new
Structural and enzymological characterization of immunoaffinity-purified DNA polymerase alpha.DNA primase complex from KB cells. S W Wong, L R Paborsky, Paul A Fisher, Teresa S-F Wang, D Korn The Journal of biological chemistry 1986 new
Mechanism of the idling-turnover reaction of the large (Klenow) fragment of Escherichia coli DNA polymerase I. V Mizrahi, P A Benkovic, Stephen J Benkovic Proceedings of the National Academy of Sciences of the United States of America 1986 pols set
DNA synthesis dependent on genetic recombination: characterization of a reaction catalyzed by purified bacteriophage T4 proteins. T Formosa, B M Alberts Cell 1986 complete
Computer analysis of retroviral pol genes: assignment of enzymatic functions to specific sequences and homologies with nonviral enzymes. M S Johnson, M A McClure, D F Feng, J Gray, R F Doolittle Proceedings of the National Academy of Sciences of the United States of America 1986 pols set
Studies of the DNA helicase-RNA primase unit from bacteriophage T4. A trinucleotide sequence on the DNA template starts RNA primer synthesis. T A Cha, B M Alberts The Journal of biological chemistry 1986 complete
Chemical characterization and purification of the beta subunit of the DNA polymerase III holoenzyme from an overproducing strain. K O Johanson, T E Haynes, Charles S McHenry The Journal of biological chemistry 1986 new
Capacity of RecA protein to bind preferentially to UV lesions and inhibit the editing subunit (epsilon) of DNA polymerase III: a possible mechanism for SOS-induced targeted mutagenesis. Chengping Lu, R H Scheuermann, H Echols Proceedings of the National Academy of Sciences of the United States of America 1986 new
Interactions of the DNA polymerase and gene 4 protein of bacteriophage T7. Protein-protein and protein-DNA interactions involved in RNA-primed DNA synthesis. H Nakai, Charles C Richardson The Journal of biological chemistry 1986 pols set
Lactate dehydrogenase and glyceraldehyde-phosphate dehydrogenase are single-stranded DNA-binding proteins that affect the DNA-polymerase-alpha-primase complex. Frank Grosse, Heinz Peter Nasheuer, S Scholtissek, U Schomburg Eur J Biochem 1986 new
Evidence of the existence of a high molecular weight form of DNA polymerase alpha in sea urchin eggs. M Shioda Cell Struct Funct 1986 new
On the fidelity of DNA synthesis. Pyrophosphate-induced misincorporation allows detection of two proofreading mechanisms. Thomas A Kunkel, R A Beckman, Lawrence A Loeb The Journal of biological chemistry 1986 topics set
The base substitution fidelity of eucaryotic DNA polymerases. Mispairing frequencies, site preferences, insertion preferences, and base substitution by dislocation. Thomas A Kunkel, P S Alexander The Journal of biological chemistry 1986 new
Role of DNA polymerase alpha and DNA primase in simian virus 40 DNA replication in vitro. Y Murakami, C R Wobbe, L Weissbach, F B Dean, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1986 new
Inhibition of herpes simplex virus DNA polymerase by purine ribonucleoside monophosphates. K B Frank, Yung-Chi Cheng The Journal of biological chemistry 1986 new
Comparison of nucleotide interactions in water, proteins, and vacuum: model for DNA polymerase fidelity. John Petruska, L C Sowers, Myron F Goodman Proceedings of the National Academy of Sciences of the United States of America 1986 new
Inhibition of DNA polymerase alpha by gossypol. L J Rosenberg, R C Adlakha, D M Desai, P N Rao Biochimica et biophysica acta 1986 new
DNA polymerase-alpha: enzymology, function, fidelity, and mutagenesis. Lawrence A Loeb, P K Liu, M Fry Prog Nucleic Acid Res Mol Biol 1986 new
The adenovirus DNA binding protein and adenovirus DNA polymerase interact to catalyze elongation of primed DNA templates. J O Lindenbaum, J Field, Jerard Hurwitz The Journal of biological chemistry 1986 new
Exonuclease activity associated with a multiprotein form of HeLa cell DNA polymerase alpha. Purification and properties of the exonuclease. W Skarnes, P Bonin, E Baril The Journal of biological chemistry 1986 new
Dissection of RNA-primed DNA synthesis catalyzed by gene 4 protein and DNA polymerase of bacteriophage T7. Coupling of RNA primer and DNA synthesis. H Nakai, Charles C Richardson The Journal of biological chemistry 1986 new
Comparative inhibitory effects of suramin and other selected compounds on the infectivity and replication of human T-cell lymphotropic virus (HTLV-III)/lymphadenopathy-associated virus (LAV). Jan Balzarini, Hiroyuki Mitsuya, Erik De Clercq, S Broder International journal of cancer. Journal international du cancer 1986 new
[Effect of ethanol on the DNA-polymerase activity in the liver subcellular fractions of adult and old rats]. E L Levitskiĭ, A Ia Litoshenko Biull Eksp Biol Med 1986 new
DNA polymerases of rabbit mammary gland: partial purification, characterization and changes in DNA polymerase activities as a function of physiological state. W Niedbalski, L Zwierzchowski, L D Wasilewska Int J Biochem 1986 new
Initiation of simian virus 40 DNA replication in vitro: aphidicolin causes accumulation of early-replicating intermediates and allows determination of the initial direction of DNA synthesis. R S Decker, Masamitsu Yamaguchi, R Possenti, M L DePamphilis Molecular and cellular biology 1986 new
O4-Methyl-, O4-ethyl-, and O4-isopropylthymidine 5'-triphosphates as analogues of thymidine 5'-triphosphate: kinetics of incorporation by Escherichia coli DNA polymerase I. B Singer, F Chavez, S J Spengler Biochemistry 1986 pols set
Stimulation of human neuroblastoma DNA polymerase alpha and primase activities by a protein factor isolated from rat liver chromatin. S Takada, A Torres-Rosado, S Ray, S Basu Proceedings of the National Academy of Sciences of the United States of America 1986 new
Genetic variation in HTLV-III/LAV over time in patients with AIDS or at risk for AIDS. B H Hahn, G M Shaw, M E Taylor, R R Redfield, P D Markham, S Z Salahuddin, F Wong-Staal, R C Gallo, E S Parks, W P Parks Science 1986 new
Structural characterization of reverse transcriptase and endonuclease polypeptides of the acquired immunodeficiency syndrome retrovirus. M M Lightfoote, J E Coligan, T M Folks, A S Fauci, M A Martin, S Venkatesan J Virol 1986 pols set
Characterization of DNA polymerase induced by salmon herpesvirus, Oncorhynchus masou virus. S Suzuki, T Kimura, Mineo Saneyoshi The Journal of general virology 1986 new
Interaction of mutant thioredoxins of Escherichia coli with the gene 5 protein of phage T7. The redox capacity of thioredoxin is not required for stimulation of DNA polymerase activity. H E Huber, M Russel, P Model, Charles C Richardson The Journal of biological chemistry 1986 new
Initiation of phage phi 29 DNA replication by mutants with deletions at the carboxyl end of the terminal protein. A Zaballos, Margarita Salas, R P Mellado Gene 1986 pols set
Synthesis and properties of oligonucleotides containing 2'-deoxynebularine and 2'-deoxyxanthosine. R Eritja, D M Horowitz, P A Walker, J P Ziehler-Martin, M S Boosalis, Myron F Goodman, K Itakura, B E Kaplan Nucleic acids research 1986 new
Homology between DNA polymerases of poxviruses, herpesviruses, and adenoviruses: nucleotide sequence of the vaccinia virus DNA polymerase gene. P L Earl, E V Jones, B Moss Proceedings of the National Academy of Sciences of the United States of America 1986 new
Human cytomegalovirus-induced DNA polymerase and its interaction with the triphosphates of 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-methyluracil, -5-iodocytosine, and -5-methylcytosine. E C Mar, J F Chiou, Yung-Chi Cheng, E S Huang J Virol 1985 new
Analysis of secondary structures in M13mp8 (+) single-stranded DNA by the pausing of DNA polymerase alpha. B Reckmann, Frank Grosse, Claus Urbanke, R Frank, H Blöcker, Gerhard Krauss Eur J Biochem 1985 new
The polymerase subunit of DNA polymerase III of Escherichia coli. II. Purification of the alpha subunit, devoid of nuclease activities. Hisaji Maki, Arthur Kornberg The Journal of biological chemistry 1985 pols set
Nuclear Overhauser effect studies of the conformations and binding site environments of deoxynucleoside triphosphate substrates bound to DNA polymerase I and its large fragment. L J Ferrin, A S Mildvan Biochemistry 1985 pols set
Dynamics of DNA polymerase III holoenzyme of Escherichia coli in replication of a multiprimed template. Mike E O'Donnell, Arthur Kornberg The Journal of biological chemistry 1985 partial results
Genetic mapping and DNA sequence analysis of mutations in the polA gene of Escherichia coli. Catherine M Joyce, D M Fujii, H S Laks, C M Hughes, Nigel D F Grindley Journal of molecular biology 1985 pols set
Selection and characterisation of acyclovir-resistant herpes simplex virus type 1 mutants inducing altered DNA polymerase activities. Brendan A Larder, G Darby Virology 1985 new
The polymerase subunit of DNA polymerase III of Escherichia coli. I. Amplification of the dnaE gene product and polymerase activity of the alpha subunit. Hisaji Maki, T Horiuchi, Arthur Kornberg The Journal of biological chemistry 1985 pols set
Reduced in vivo mutagenesis by mutant herpes simplex DNA polymerase involves improved nucleotide selection. J D Hall, Phillip A Furman, M H St Clair, C W Knopf Proceedings of the National Academy of Sciences of the United States of America 1985 new
Elucidation of the mechanism of selective inhibition of mammalian DNA polymerase alpha by 2-butylanilinopurines: development and characterization of 2-(p-n-butylanilino)adenine and its deoxyribonucleotides. N N Khan, George E Wright, L W Dudycz, Neal C Brown Nucleic acids research 1985 pols set
Mutually exclusive inhibition of herpesvirus DNA polymerase by aphidicolin, phosphonoformate, and acyclic nucleoside triphosphates. K B Frank, Yung-Chi Cheng Antimicrob Agents Chemother 1985 new
The mutational specificity of DNA polymerase-beta during in vitro DNA synthesis. Production of frameshift, base substitution, and deletion mutations. Thomas A Kunkel The Journal of biological chemistry 1985 partial results
Molecular assessment of S1 endonuclease-resistant snapback hairpin loops generated by DNA polymerase I during the in-vitro nick translation reaction. M V Norgard Appl Biochem Biotechnol 1985 new
Reduced repair of X-ray-induced DNA lesions in cells without functioning DNA polymerase alpha. U Lönn, S Lönn Radiat Res 1985 new
Activities of arabinosyladenine monophosphate and 9-(1,3-dihydroxy-2-propoxymethyl)guanine against ground squirrel hepatitis virus in vivo as determined by reduction in serum virion-associated DNA polymerase. D F Smee, S S Knight, A E Duke, W S Robinson, T R Matthews, P L Marion Antimicrob Agents Chemother 1985 new
A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes. Stanley Tabor, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 1985 pols set
Inhibitors of reverse transcriptase and retrovirus replication. Erik De Clercq Arzneimittel-Forschung 1985 new
Purification and characterization of a DNA polymerase beta from Drosophila*. Kengo Sakaguchi, J B Boyd The Journal of biological chemistry 1985 new
Nucleotide sequence and expression of an AIDS-associated retrovirus (ARV-2). R Sanchez-Pescador, M D Power, P J Barr, K S Steimer, M M Stempien, S L Brown-Shimer, W W Gee, A Renard, A Randolph, J A Levy Science 1985 new
Analysis of DNA polymerase reaction products for detecting hepatitis B virus in serum--comparison with spot hybridization technique. F Imazeki, Masao Omata, Osamu Yokosuka, Y Matsuyama, Yasutomo Ito, K Okuda Hepatology 1985 new
Monoclonal antibodies against human DNA polymerase-alpha inhibit DNA replication in permeabilized human cells. M R Miller, R G Ulrich, Teresa S-F Wang, D Korn The Journal of biological chemistry 1985 pols set
Heat-induced alterations in DNA polymerase activity of HeLa cells and of isolated nuclei. Relation to cell survival. H H Kampinga, J B Jorritsma, A W Konings Int J Radiat Biol Relat Stud Phys Chem Med 1985 new
Site-specifically modified oligodeoxyribonucleotides as templates for Escherichia coli DNA polymerase I. D O'Connor, G Stöhrer Proceedings of the National Academy of Sciences of the United States of America 1985 pols set
Interaction of ribonuclease H from Drosophila melanogaster embryos with DNA polymerase-primase. R A DiFrancesco, I. Robert Lehman The Journal of biological chemistry 1985 new
Inhibition of DNA polymerase alpha activity by proteins from rat liver. C M Klinge, D K Liu Int J Biochem 1985 new
Interaction of DNA polymerase and nucleotide analog triphosphates. K B Frank, J F Chiou, Yung-Chi Cheng Adv Enzyme Regul 1985 topics set
Monoclonal antibody specific for chicken DNA polymerase alpha associated with DNA primase. Fumiko Hirose, Padmini Kedar, Tomonori Takahashi, Akio Matsukage Biochem Biophys Res Commun 1985 new
Inhibition of DNA replication and DNA polymerase alpha activity by monoclonal anti-(DNA polymerase alpha) immunoglobulin G and F(ab) fragments. M R Miller, C Seighman, R G Ulrich Biochemistry 1985 new
On the fidelity of DNA replication: manganese mutagenesis in vitro. R A Beckman, A S Mildvan, Lawrence A Loeb Biochemistry 1985 pols set
3'-Deoxy-3'-fluorothymidinetriphosphate: inhibitor and terminator of DNA synthesis catalysed by DNA polymerase beta, terminal deoxynucleotidyl transferase and DNA polymerase I. E Matthes, C Lehmann, B Drescher, W Büttner, P Langen Biomed Biochim Acta 1985 new
Template properties of ultraviolet-irradiated poly(dC) replicated by E. coli DNA polymerase I: indication for a role of apyrimidinic-sites in UV-induced mutagenesis. Serge Boiteux, J Pierre, Jacques Laval Biochimie 1985 pols set
Purification and characterization of murine retroviral reverse transcriptase expressed in Escherichia coli. M J Roth, N Tanese, S P Goff The Journal of biological chemistry 1985 partial results
Fidelity of DNA polymerases isolated from regenerating liver chromatin of aging Mus musculus. J R Silber, M Fry, G M Martin, Lawrence A Loeb The Journal of biological chemistry 1985 new
Poly(dG-dC) in the Z-form inhibits E. coli DNA polymerase I and AMV DNA polymerase activity. S K Brahmachari, N Ramesh, M R Das, V K Parnaik Biochem Int 1985 pols set
Suramin inhibits duck hepatitis B virus DNA polymerase activity. K Tsiquaye, A Zuckerman J Hepatol 1985 new
Effects of aphidicolin and/or 2',3'-dideoxythymidine on DNA repair induced in HeLa cells by four types of DNA-damaging agents. K Yamada, Fumio Hanaoka, Masami Yamada The Journal of biological chemistry 1985 new
Interaction of DNA polymerase I of Escherichia coli with nucleotides. Antagonistic effects of single-stranded polynucleotide homopolymers. O Muise, E Holler Biochemistry 1985 pols set
Properties and applications of new monoclonal antibodies raised against calf DNA polymerase alpha. J A Swack, E Karawya, W Albert, J Fedorko, John D Minna, Samuel H Wilson Analytical biochemistry 1985 new
Effects of VP-16 on cell growth and metabolism of nucleic acids in mouse leukemia L-1210 cells and on the activity of DNA polymerase I of E. coli. Y Izumi, T Usui, T Okazaki, T Mochizuki, H Ishikura, M Tashima, H Sawada, H Uchino Nippon Ketsueki Gakkai Zasshi 1985 pols set
Inhibition of DNA polymerase alpha, DNA polymerase beta, terminal deoxynucleotidyl transferase, and DNA ligase II by poly(ADP-ribosyl)ation reaction in vitro. K Yoshihara, A Itaya, Y Tanaka, Y Ohashi, K Ito, H Teraoka, K Tsukada, Akio Matsukage, T Kamiya Biochem Biophys Res Commun 1985 new
Inhibition of DNA polymerase alpha from leukemic and normal human cells by partially thiolated human deoxyribonucleic acids. Y K Ho, A R Reddy, J Aradi, J Minowada, T J Bardos Cancer Biochem Biophys 1985 new
Initiation of DNA synthesis by the calf thymus DNA polymerase-primase complex. A M. Holmes, E Cheriathundam, F J Bollum, L M Chang The Journal of biological chemistry 1985 new
Isolation of the gene encoding yeast DNA polymerase I. L M Johnson, M Snyder, L M Chang, R W Davis, Judith L Campbell Cell 1985 topics set
Initiation of DNA replication at the primary origin of bacteriophage T7 by purified proteins. Site and direction of initial DNA synthesis. C W Fuller, Charles C Richardson The Journal of biological chemistry 1985 pols set
[Effect of glucose metabolic products on the growth of a recombinant Escherichia coli strain--a superproducer of DNA-polymerase]. S A Soktoev, I N Dugan, A N Shkidchenko Mikrobiologiia 1985 new
[Mechanisms of radiation impairment of DNA biosynthesis. Separation, partial purification, characteristics of and changes in DNA polymerase alpha and beta activities of rat bone marrow at early stages after gamma irradiation and comparison with the status of repair and replication biosynthesis of DNA]. V K Mazurik, L I Ushenkova Radiobiologiia 1985 new
Mutations in the herpes simplex virus major DNA-binding protein gene leading to altered sensitivity to DNA polymerase inhibitors. H C Chiou, Sandra K Weller, Donald M Coen Virology 1985 new
Structure-function studies of the bacteriophage T4 DNA polymerase. Isolation of a novel suppressor mutant. Linda J Reha-Krantz, J K Lambert Journal of molecular biology 1985 complete
Differential inhibition of human placental DNA polymerases delta and alpha by BuPdGTP and BuAdATP. Marietta Y W T Lee, N L Toomey, George E Wright Nucleic acids research 1985 new
Stimulation of Rauscher leukemia virus DNA polymerase DNA-directed DNA synthesis by cationic trypanocides and polyamines. S L Marcus, D P Petrylak, J J Burchenal, C J Bacchi Cancer research 1985 new
Characterization of a Mr = 56,000 polypeptide associated with 10S DNA polymerase alpha purified from calf thymus using monoclonal antibody. S Masaki, Katsuyuki Tamai, R Suzuki, K Tanabe, Tomonori Takahashi, Shonen Yoshida Nucleic acids research 1985 new
Interaction of Epstein-Barr virus DNA polymerase and 5'-triphosphates of several antiviral nucleoside analogs. J F Chiou, Yung-Chi Cheng Antimicrob Agents Chemother 1985 new
Overproduction and purification of protein P6 of Bacillus subtilis phage phi 29: role in the initiation of DNA replication. R Pastrana, José María Lázaro, Luis Blanco, J A García, E Méndez, Margarita Salas Nucleic acids research 1985 new
Involvement of DNA-polymerase activities in mouse-blastocyst differentiation in vitro. H Alexandre Differentiation 1985 new
A defective phage system reveals bacteriophage T4 replication origins that coincide with recombination hot spots. K N Kreuzer, B M Alberts Proceedings of the National Academy of Sciences of the United States of America 1985 complete
Response of CHO cell DNA polymerase alpha to dCTP and dTTP pool imbalance: relation to DNA synthesis inhibition, survival and mutation. C N Newman, J H Miller Basic Life Sci 1985 new
Characterization of the AIDS-associated retrovirus reverse transcriptase and optimal conditions for its detection in virions. A D Hoffman, B Banapour, J A Levy Virology 1985 pols set
[Effect of aclacinomycin B on DNA polymerase II of tumor cells]. Z R Li, J B Feng, R Han, M B Yin, L J Xia Zhongguo Yao Li Xue Bao 1985 new
Influence of neighboring bases on DNA polymerase insertion and proofreading fidelity. John Petruska, Myron F Goodman The Journal of biological chemistry 1985 topics set
Demonstration of a stimulatory protein for virus-specified DNA polymerase in phorbol ester-treated Epstein-Barr virus-carrying cells. J F Chiou, J K Li, Yung-Chi Cheng Proceedings of the National Academy of Sciences of the United States of America 1985 new
Purification of Epstein-Barr virus DNA polymerase from P3HR-1 cells. B Kallin, L Sternås, A K Saemundssen, J Luka, H Jörnvall, B Eriksson, P Z Tao, M T Nilsson, G Klein J Virol 1985 new
Assignment of the human gene for DNA polymerase alpha to the X chromosome. Fumio Hanaoka, M Tandai, Hiroshi Miyazawa, T Hori, Masami Yamada Japanese journal of cancer research : Gann 1985 new
Effect of DNA polymerase I and DNA helicase II on the turnover rate of UvrABC excision nuclease. I Husain, B Van Houten, D C Thomas, M Abdel-Monem, A Sancar Proceedings of the National Academy of Sciences of the United States of America 1985 new
Characterization of a temperature-sensitive mutant of mouse FM3A cells defective in DNA replication. Y Murakami, H Yasuda, Hiroshi Miyazawa, Fumio Hanaoka, Masami Yamada Proceedings of the National Academy of Sciences of the United States of America 1985 new
DNA primase-DNA polymerase alpha from simian cells. Modulation of RNA primer synthesis by ribonucleoside triphosphates. Masamitsu Yamaguchi, E A Hendrickson, M L DePamphilis The Journal of biological chemistry 1985 pols set
Chinese hamster ovary cell mutants resistant to DNA polymerase inhibitors. I. Isolation and biochemical genetic characterization. J K Vishwanatha, N C Mishra Mol Gen Genet 1985 new
Electrostatic field of the large fragment of Escherichia coli DNA polymerase I. J Warwicker, D Ollis, F M Richards, Thomas A Steitz Journal of molecular biology 1985 pols set
Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro. Hiroshi Ide, Y W Kow, Susan S Wallace Nucleic acids research 1985 pols set
The primase activity of DNA polymerase alpha from calf thymus. Frank Grosse, Gerhard Krauss The Journal of biological chemistry 1985 new
Effect of DNA polymerase inhibitors on the replication of human cytomegalovirus. Brief report. E Gönczöl, S A Plotkin Arch Virol 1985 pols set
Chinese hamster ovary cell mutants resistant to DNA polymerase inhibitors. II. Segregational analysis and DNA transfection of the aphr gene. J K Vishwanatha, N C Mishra Mol Gen Genet 1985 new
T4 DNA polymerase (3'-5') exonuclease, an enzyme for the detection and quantitation of stable DNA lesions: the ultraviolet light example. P W Doetsch, G L Chan, W A Haseltine Nucleic acids research 1985 pols set
DNA polymerase III holoenzyme of Escherichia coli: components and function of a true replicative complex. Charles S McHenry Molecular and cellular biochemistry 1985 pols set
[E. coli DNA polymerase. A study of the mechanism of primer binding using oligothymidylate analogs with ethylated internucleotide phosphate groups]. A S Levina, G A Nevinskiĭ, Olga I Lavrik Bioorg Khim 1985 new
Redesigning trypsin: alteration of substrate specificity. C S Craik, C Largman, T Fletcher, S Roczniak, P J Barr, R Fletterick, W J Rutter Science 1985 new
DNA primase-DNA polymerase alpha from simian cells: sequence specificity of initiation sites on simian virus 40 DNA. Masamitsu Yamaguchi, E A Hendrickson, M L DePamphilis Molecular and cellular biology 1985 new
Complete replication of templates by Escherichia coli DNA polymerase III holoenzyme. Mike E O'Donnell, Arthur Kornberg The Journal of biological chemistry 1985 pols set
[DNA-polymerase activity and DNA synthesis in the hepatocyte nuclear matrix]. Iu Iu Malinovskiĭ, V G Bezlepkin, A I Gaziev Mol Biol (Mosk) 1985 new
A newly detected class of mammalian single strand-specific DNA-binding proteins. Effects on DNA polymerase alpha-catalyzed DNA synthesis. M Sapp, H König, H D Riedel, A Richter, R Knippers The Journal of biological chemistry 1985 pols set
The mutational specificity of DNA polymerases-alpha and -gamma during in vitro DNA synthesis. Thomas A Kunkel The Journal of biological chemistry 1985 new
Control of DNA polymerase alpha, beta and gamma activities in heat- and cold-sensitive mammalian cell-cycle mutants. E Schneider, B Müller, R Schindler Biochimica et biophysica acta 1985 new
Purification and characterization of DNA polymerase alpha of Chinese hamster ovary cells. N N Khan, Neal C Brown Mol Cell Biochem 1985 new
Dissociation and reconstitution of a DNA polymerase alpha-primase complex. Motoshi Suzuki, Takemi Enomoto, Fumio Hanaoka, Masami Yamada J Biochem 1985 new
Characterization of DNA polymerase I*, a form of DNA polymerase I found in Escherichia coli expressing SOS functions. D Lackey, S W Krauss, Stuart Linn The Journal of biological chemistry 1985 partial results
On the fidelity of DNA polymerase alpha: the influence of alpha-thio dNTPs, Mn2+ and mismatch repair. A Rienitz, Frank Grosse, H Blöcker, R Frank, Gerhard Krauss Nucleic acids research 1985 new
[Physiology of the growth and supersynthesis of DNA-polymerase in Escherichia coli during 2-stage continuous cultivation]. A N Shkidchenko, S A Soktoev, L V Gurina, E L Golovlev Mikrobiologiia 1985 new
Mammalian DNA helicase. Ulrich Hübscher, H P Stalder Nucleic acids research 1985 new
Complete nucleotide sequence of the AIDS virus, HTLV-III. L Ratner, W Haseltine, R Patarca, K J Livak, B Starcich, S F Josephs, E R Doran, J A Rafalski, E A Whitehorn, K Baumeister Nature 1985 new
[Complex of DNA polymerase alpha with 3'----5'-exonuclease from the regenerating rat liver]. T P Kravetskaia, N E Kleĭner, L T Timchenko, V M Krutiakov Dokl Akad Nauk SSSR 1985 new
Inhibition of cellular DNA polymerase alpha and human cytomegalovirus-induced DNA polymerase by the triphosphates of 9-(2-hydroxyethoxymethyl)guanine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine. E C Mar, J F Chiou, Yung-Chi Cheng, E S Huang J Virol 1985 new
A DNA template recognition protein: partial purification from mouse liver and stimulation of DNA polymerase alpha. M Fry, J Lapidot, P Weisman-Shomer Biochemistry 1985 new
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. C W Greider, E H Blackburn Cell 1985 topics set
Base-pairing properties of N4-methoxydeoxycytidine 5'-triphosphate during DNA synthesis on natural templates, catalyzed by DNA polymerase I of Escherichia coli. S T Reeves, K L Beattie Biochemistry 1985 pols set
Cytomegalovirus DNA polymerase inhibition and kinetics. B Wahren, B Eriksson Adv Enzyme Regul 1985 new
Selective DNA-amplification induced by carcinogens (initiators): evidence for a role of proteases and DNA polymerase alpha. R Heilbronn, J R Schlehofer, A O Yalkinoglu, H Zur Hausen Int J Cancer 1985 new
Fidelity of DNA polymerase-beta in neurons from young and very aged mice. K Subba Rao, G M Martin, Lawrence A Loeb Journal of neurochemistry 1985 new
Bacteriophage SPO1 DNA polymerase and the activity of viral gene 31. G L De Antoni, N E Besso, G E Zanassi, A N Sarachu, O Grau Virology 1985 new
Purification of a DNA primase activity from the yeast Saccharomyces cerevisiae. Primase can be separated from DNA polymerase I. F E Wilson, A Sugino The Journal of biological chemistry 1985 new
Properties of hepatitis B virus associated DNA polymerase. S H Oh, Y H Park Yonsei Med J 1985 new
DNA polymerase alpha and models for proofreading. J Abbotts, Lawrence A Loeb Nucleic acids research 1985 new
Inhibition of HTLV-III/LAV replication by foscarnet. P S Sarin, Y Taguchi, Daekyu Sun, A Thornton, R C Gallo, Bo Oberg Biochem Pharmacol 1985 new
Domain of E. coli DNA polymerase I showing sequence homology to T7 DNA polymerase. David L Ollis, C Kline, Thomas A Steitz Nature 1985 pols set
Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain. J S Gibbs, H C Chiou, J D Hall, D W Mount, M J Retondo, Sandra K Weller, Donald M Coen Proceedings of the National Academy of Sciences of the United States of America 1985 new
Effect of benzo[a]pyrene on DNA synthesis and DNA polymerase activity of rat liver nuclei. I Salazar, L Tarragó-Litvak, Simon Litvak, L Gil Biochem Pharmacol 1985 new
Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locus. Donald M Coen, H E Fleming, L K Leslie, M J Retondo Journal of virology 1985 new
Cyclobutane pyrimidine dimers and (6-4) photoproducts block polymerization by DNA polymerase I. G L Chan, P W Doetsch, W A Haseltine Biochemistry 1985 pols set
[Studies on the serum DNA polymerase in leukemic patients]. L Y Tsai, C H Chaing, W T Liu, J S Chen Gaoxiong Yi Xue Ke Xue Za Zhi 1985 new
Characterization of a 3'----5' exonuclease activity in the phage phi 29-encoded DNA polymerase. Luis Blanco, Margarita Salas Nucleic acids research 1985 pols set
A rapid single-stranded cloning strategy for producing a sequential series of overlapping clones for use in DNA sequencing: application to sequencing the corn mitochondrial 18 S rDNA. R M Dale, B A McClure, J P Houchins Plasmid 1985 pols set
Ribonucleoside and deoxyribonucleoside triphosphate pools during 2-aminopurine mutagenesis in T4 mutator-, wild type-, and antimutator-infected Escherichia coli. R L Hopkins, Myron F Goodman The Journal of biological chemistry 1985 complete
[Changes in HBV-specific DNA polymerase activity in relation to the severity of HBsAg positive chronic liver disease]. H Kawakami, M Kikkawa, T Matsuura, H Kawamoto, Yoh Watanabe, Y Ikemoto, S Suemori, G Kaziyama, S Aimitsu, H Takeno Nippon Shokakibyo Gakkai Zasshi 1985 new
DNA polymerase activity in a repair-deficient human cell line. C O Joe, J O Norman, T R Irvin, David L Busbee Biochem Biophys Res Commun 1985 new
On the fidelity of DNA replication: use of synthetic oligonucleotide-initiated reactions. J Abbotts, Lawrence A Loeb Biochimica et biophysica acta 1985 new
Role of DNA polymerase alpha in chromosomal aberration production by ionizing radiation. M A Bender Ann N Y Acad Sci 1985 new
Quantification of lymphocyte activation by measurement of DNA polymerase alpha activity. M D Talbot, M K Jasani J Immunol Methods 1985 new
[Analysis of DNA polymerase reaction products for detecting hepatitis B virus in serum--comparison with spot hybridization technique]. F Imazeki, Masao Omata, Osamu Yokosuka, Y Matsuyama, Yasutomo Ito, K Okuda Nippon Shokakibyo Gakkai Zasshi 1985 new
Induction of DNA polymerase alpha in senescent cultures of normal and Werner's syndrome cultured skin fibroblasts. W R Pendergrass, A C Saulewicz, D Salk, T Norwood J Cell Physiol 1985 new
Cell-cycle dependence and properties of the HeLa cell DNA polymerase system. C Delfini, E Alfani, V De Venezia, G Oberholtzer, C Tomasello, T Eremenko, P Volpe Proceedings of the National Academy of Sciences of the United States of America 1985 new
A fidelity assay using "dideoxy" DNA sequencing: a measurement of sequence dependence and frequency of forming 5-bromouracil X guanine base mispairs. R S Lasken, Myron F Goodman Proceedings of the National Academy of Sciences of the United States of America 1985 new
Purification and characterization of DNA polymerase from the archaebacterium Sulfolobus acidocaldarius. L J Klimczak, F Grummt, K J Burger Nucleic acids research 1985 new
Nucleotide sequence of the AIDS virus, LAV. S Wain-Hobson, P Sonigo, O Danos, S Cole, M Alizon Cell 1985 new
Increase in DNA polymerase alpha in nuclei of chicken kidney cells after avian adenovirus infection. Akio Matsukage, Masamitsu Yamaguchi, H Yasue, M Ishibashi Jpn J Cancer Res 1985 new
An alpha-like DNA polymerase from Halobacterium halobium. M Nakayama, M Kohiyama Eur J Biochem 1985 new
[DNA polymerase beta from the rat liver. Isolation, properties and inhibitory analysis of a homogeneous preparation]. A M Atrazhev, M K Kukhanova Bioorg Khim 1985 new
Strand break repair, DNA polymerase activity and heat radiosensitization in thermotolerant cells. J B Jorritsma, H H Kampinga, A H Scaf, A W Konings Int J Hyperthermia 1985 new
Measurement of DNA polymerase beta in skin fibroblast cell lines from patients with ataxia telangiectasia. J B Mitchell, E Karawya, T J Kinsella, Samuel H Wilson Mutation research 1985 pols set
Initiation of DNA replication at the primary origin of bacteriophage T7 by purified proteins. Initiation of bidirectional synthesis. C W Fuller, Charles C Richardson The Journal of biological chemistry 1985 pols set
Expression in Escherichia coli of a fusion protein product containing a region of the adenovirus DNA polymerase. D Rekosh, J Lindenbaum, J Brewster, L M Mertz, Jerard Hurwitz, L Prestine Proceedings of the National Academy of Sciences of the United States of America 1985 new
Location of the serine residue involved in the linkage between the terminal protein and the DNA of phage phi 29. José M Hermoso, E Méndez, F Soriano, Margarita Salas Nucleic acids research 1985 pols set
Replication of phage phi 29 DNA with purified terminal protein and DNA polymerase: synthesis of full-length phi 29 DNA. Luis Blanco, Margarita Salas Proceedings of the National Academy of Sciences of the United States of America 1985 pols set
E receptor-related immunosuppressive factor in malignant pleural fluid and plasma: molecular mechanism of action on DNA-polymerase-alpha. S K Oh, D P Lapenson J Immunol 1985 new
Purification and characterization of two forms of DNA polymerase alpha from mouse FM3A cells: a DNA polymerase alpha-primase complex and a free DNA polymerase alpha. Takemi Enomoto, Motoshi Suzuki, Mayumi Takahashi, K Kawasaki, Yoh Watanabe, K Nagata, Fumio Hanaoka, Masami Yamada Cell Struct Funct 1985 new
Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. R K Saiki, S Scharf, F Faloona, K B Mullis, G T Horn, H A Erlich, Norman Arnheim Science (New York, N.Y.) 1985 topics set
Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP. David L Ollis, P Brick, R Hamlin, N G Xuong, Thomas A Steitz Nature 1985 complete
Rate-limiting steps in the DNA polymerase I reaction pathway. V Mizrahi, R N Henrie, J F Marlier, Kenneth A Johnson, Stephen J Benkovic Biochemistry 1985 new
Bacteriophage T4 DNA replication protein 41. Cloning of the gene and purification of the expressed protein. D M Hinton, Lynn L Silver, Nancy G Nossal The Journal of biological chemistry 1985 complete
Quantitative structure-activity relationships of 6-anilinouracils as inhibitors of Bacillus subtilis DNA polymerase III. George E Wright, Joseph J Gambino J Med Chem 1984 new
Escherichia coli DNA polymerase I. Construction of a polA plasmid for amplification and an improved purification scheme. E G Minkley, A T Leney, J B Bodner, M M Panicker, W E Brown The Journal of biological chemistry 1984 pols set
Site-specific modification of Escherichia coli DNA polymerase I large fragment with pyridoxal 5'-phosphate. A K Hazra, S Detera-Wadleigh, Samuel H Wilson Biochemistry 1984 pols set
T7 DNA polymerase is not a zinc-metalloenzyme and the polymerase and exonuclease activities are inhibited by zinc ions. I Slaby, B Lind, A Holmgren Biochem Biophys Res Commun 1984 pols set
T4 DNA polymerase. Rates and processivity on single-stranded DNA templates. D C Mace, B M Alberts Journal of molecular biology 1984 pols set
Prostaglandin D2 lowers nuclear DNA polymerase activity in cultured mastocytoma cells. M Kawamura, Y Koshihara Prostaglandins 1984 new
Single mutations at many sites within the DNA polymerase locus of herpes simplex viruses can confer hypersensitivity to aphidicolin and resistance to phosphonoacetic acid. R W Honess, D J Purifoy, D Young, R Gopal, Nick Cammack, P O'Hare The Journal of general virology 1984 new
Characterization of the stimulatory effect of T4 gene 45 protein and the gene 44/62 protein complex on DNA synthesis by T4 DNA polymerase. D C Mace, B M Alberts Journal of molecular biology 1984 partial results
Replication of bacteriophage phi 29 DNA in vitro: the roles of terminal protein and DNA polymerase. K Watabe, M Leusch, J Ito Proceedings of the National Academy of Sciences of the United States of America 1984 new
Template-dependent variation in the relative fidelity of DNA polymerase I of Escherichia coli in the presence of Mg2+ versus Mn2+. G G Hillebrand, K L Beattie Nucleic acids research 1984 pols set
Purification of a primase activity associated with DNA polymerase alpha from HeLa cells. R M Gronostajski, J Field, Jerard Hurwitz The Journal of biological chemistry 1984 new
A DNA polymerase activity is associated with Cauliflower Mosaic Virus. J Menissier, Patricia Laquel, G Lebeurier, L Hirth Nucleic acids research 1984 new
DNA polymerases and DNA topoisomerases solubilized from nuclear matrices of regenerating rat livers. Masatoyo Nishizawa, K Tanabe, Tomonori Takahashi Biochemical and biophysical research communications 1984 new
ATP(GTP)-dependent conversion of MVM parvovirus single-stranded DNA to its replicative form by a purified 10 S species of mouse DNA polymerase alpha. E A Faust, G Gloor, M F MacIntyre, R Nagy Biochimica et biophysica acta 1984 new
Synthesis and characterization of N2-(p-n-butylphenyl)-2'-deoxyguanosine and its 5'-triphosphate and their inhibition of HeLa DNA polymerase alpha. George E Wright, L W Dudycz J Med Chem 1984 new
DNA polymerase in nuclei isolated from herpes simplex virus type-2-infected cells. Characterization of the reaction product and inhibition by substrate analogs. J W Barnett, C M Reinke, S R Turk, J C Drach Biochimica et biophysica acta 1984 new
Heterogeneity in the radiation survival curves and biochemical properties of human lung cancer cell lines. G Morstyn, A Russo, D N Carney, E Karawya, Samuel H Wilson, J B Mitchell Journal of the National Cancer Institute 1984 new
Inhibition of DNA polymerase alpha by 2',3'-dideoxyribonucleoside 5'-triphosphates: effect of manganese ion. K Ono, M Ogasawara, Y Iwata, H Nakane Biomed Pharmacother 1984 new
Primary structural comparison of RNA-dependent polymerases from plant, animal and bacterial viruses. G Kamer, P Argos Nucleic acids research 1984 new
Correlation of DNA polymerase activities with the initiation of DNA synthesis. A M Otto Adv Exp Med Biol 1984 new
DNA polymerase activities of mammalian cell-cycle mutants and "wild-type" cells in different states of proliferative activity and quiescence. E Schneider, B Müller, R Schindler Adv Exp Med Biol 1984 new
Inhibition of DNA polymerase alpha activity by ammonium 21-tungsto-9-antimoniate (HPA23). K Ono, H Nakane, T Matsumoto, F Barré-Sinoussi, J C Chermann Nucleic Acids Symp Ser 1984 new
Purification of a DNA polymerase-DNA primase complex from calf thymus glands. L M Chang, E Rafter, C Augl, F J Bollum The Journal of biological chemistry 1984 new
[Several enzymic properties of the DNA-polymerase alpha complexes with antibodies]. V G Demin, V M Mikhaĭlov, Z I Uspenskaia, V M Bozhkov Biokhimiia 1984 new
Association between primase and DNA polymerase alpha in murine cells. Magali Philippe, R Sheinin, A M de Recondo Adv Exp Med Biol 1984 new
Interaction of DNA accessory proteins with DNA polymerase beta of the Novikoff hepatoma. R R Meyer, D C Thomas, T J Koerner, D C Rein Adv Exp Med Biol 1984 new
Identification of the breakage-reunion subunit of T4 DNA topoisomerase. T C Rowe, K M Tewey, L F Liu The Journal of biological chemistry 1984 complete
Adenosine 5'-O-(3-thiotriphosphate) can support the formation of an initiation complex between the DNA polymerase III holoenzyme and primed DNA. K O Johanson, Charles S McHenry The Journal of biological chemistry 1984 pols set
De novo DNA synthesis by yeast DNA polymerase I associated with primase activity. Paolo Plevani, G Magni, Marco Foiani, L M Chang, G Badaracco Adv Exp Med Biol 1984 new
Purification and characterization of the bacteriophage T4 dda protein. A DNA helicase that associates with the viral helix-destabilizing protein. C V Jongeneel, T Formosa, B M Alberts The Journal of biological chemistry 1984 complete
Involvement of DNA polymerase alpha in host cell reactivation of UV-irradiated herpes simplex virus. Yoshitaka Nishiyama, Shonen Yoshida, K Maeno J Virol 1984 new
Variation of DNA polymerase activities and DNA synthesis in mouse mammary gland during pregnancy and early lactation. L Zwierzchowski, D Kleczkowska, W Niedbalski, I Grochowska Differentiation 1984 new
The effect of nitroso-chloramphenicol on mitochondrial DNA polymerase activity. L O Lim, W H Abou-Khalil, A A Yunis, S Abou-Khalil J Lab Clin Med 1984 new
Monoclonal antibodies specific for the alpha subunit of the Escherichia coli DNA polymerase III holoenzyme. Y H Wu, M A Franden, J R Hawker, Charles S McHenry The Journal of biological chemistry 1984 pols set
Generation of genetic diversity in herpes simplex virus: an antimutator phenotype maps to the DNA polymerase locus. J D Hall, Donald M Coen, B L Fisher, M Weisslitz, S Randall, R E Almy, P T Gelep, P A Schaffer Virology 1984 new
A ribonuclease H from yeast stimulates DNA polymerase in vitro. R Karwan, H Blutsch, U Wintersberger Adv Exp Med Biol 1984 new
Genetics of herpes simplex virus. P A Schaffer, Sandra K Weller, B A Pancake, Donald M Coen The Journal of investigative dermatology 1984 new
Selective affinity chromatography of DNA polymerases with associated 3' to 5' exonuclease activities. Marietta Y W T Lee, W A Whyte Analytical biochemistry 1984 new
Molecular mechanisms of chemical mutagenesis: 9-aminoacridine inhibits DNA replication in vitro by destabilizing the DNA growing point and interacting with the DNA polymerase. M D Topal Biochemistry 1984 pols set
Properties of the adenovirus DNA polymerase. J Field, R M Gronostajski, Jerard Hurwitz The Journal of biological chemistry 1984 partial results
The interaction of DNA polymerase III and the product of the Escherichia coli mutator gene, mutD. R DiFrancesco, S K Bhatnagar, A Brown, M J Bessman The Journal of biological chemistry 1984 new
Protein-primed replication of plasmids containing the terminus of the adenovirus genome. I. Characterization of an in vitro DNA replication system dependent on adenoviral DNA sequences. R A Guggenheimer, K Nagata, J Lindenbaum, Jerard Hurwitz The Journal of biological chemistry 1984 new
DNA polymerase accessory proteins in mammalian cells. G Biamonti, O Valentini, F Cobianchi, A Falaschi, S Riva Folia Biol (Praha) 1984 new
Tight association of DNA polymerase alpha with granular structures in the nuclear matrix of chick embryo cell: immunocytochemical detection with monoclonal antibody against DNA polymerase alpha. S Yamamoto, Tomonori Takahashi, Akio Matsukage Cell Struct Funct 1984 new
[Isolation and various properties of beta DNA polymerase from the embryos of the sea urchin Strongylocentrotus intermedius]. L L Terent'ev, N A Terent'eva, V A Rasskazov Biokhimiia 1984 new
Large polypeptides of 10S DNA polymerase alpha from calf thymus: rapid isolation using monoclonal antibody and tryptic peptide mapping analysis. S Masaki, K Tanabe, Shonen Yoshida Nucleic acids research 1984 new
Further studies on calf thymus DNA polymerase delta purified to homogeneity by a new procedure. Marietta Y W T Lee, Cheng-Keat Tan, Kathleen M Downey, Antero G So Biochemistry 1984 partial results
Threonine starvation of concanavalin A treated lymphocytes impairs DNA polymerase alpha activity. G Taudou, J Wiart, J Panijel Mol Immunol 1984 new
A DNA primase that copurifies with the major DNA polymerase from the yeast Saccharomyces cerevisiae. H Singh, L B Dumas The Journal of biological chemistry 1984 new
Human DNA polymerase alpha. Compensation for heat-labile mouse DNA polymerase alpha and its gene localization on the X chromosome. Fumio Hanaoka, M Tandai, Hiroshi Miyazawa, Y Murakami, T Hori, Masami Yamada Molecular biology & medicine 1984 pols set
Increased DNA polymerase beta-activity in different regions of aging rat brain. K V Subba Rao, K Subba Rao Biochem Int 1984 new
Inhibition of human and woodchuck hepatitis virus DNA polymerase by the triphosphates of acyclovir, 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine and E-5-(2-bromovinyl)-2'-deoxyuridine. O Hantz, H S Allaudeen, T Ooka, Erik De Clercq, C Trepo Antiviral Res 1984 new
Evidence for mutagenic repair in V79 cell mutant with aphidicolin-resistant DNA polymerase-alpha. P K Liu, C C Chang, J E Trosko Somat Cell Mol Genet 1984 new
Quinolone antibiotics inhibit eucaryotic DNA polymerase alpha and beta, terminal deoxynucleotidyl transferase but not DNA ligase. R Rusquet, M Bonhommet, J C David Biochem Biophys Res Commun 1984 new
Clinicopathological response of HBsAg-positive chronic active hepatitis to adenine arabinoside: lack of correlation with DNA polymerase response. Y F Liaw, D Y Lin, T J Chen, C M Chu, I S Sheen Infection 1984 new
A 3' to 5' exonuclease activity is associated with phage 029 DNA polymerase. K Watabe, M S Leusch, J Ito Biochem Biophys Res Commun 1984 new
Absence of RNase H allows replication of pBR322 in Escherichia coli mutants lacking DNA polymerase I. T Kogoma Proceedings of the National Academy of Sciences of the United States of America 1984 new
[Effect of Yang-Yin composite mixture on DNA polymerase alpha and DNA template activity]. Z K Wu Zhong Yao Tong Bao 1984 new
DNA sequences required for the in vitro replication of adenovirus DNA. R A Guggenheimer, B W Stillman, K Nagata, F Tamanoi, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1984 new
Protein-primed replication of plasmids containing the terminus of the adenovirus genome. II. Purification and characterization of a host protein required for the replication of DNA templates devoid of the terminal protein. R A Guggenheimer, K Nagata, M Kenny, Jerard Hurwitz The Journal of biological chemistry 1984 new
RNAase-sensitive DNA-dependent DNA polymerase from rat cells transformed by avian sarcoma virus. M Kotler, J Rosenberg, B Fridlender Biochimica et biophysica acta 1984 new
Induction of DNA polymerase alpha and terminal deoxynucleotidyl transferase in the human lymphoblastoid cell line Molt-4 by the immunomodulator bestatin. G Leyhausen, W Dippold, R K Zahn, K H Meyer zum Büschenfelde, H Umezawa, W E Müller Immunopharmacology 1984 new
N6-methyldeoxyadenosine 5'-triphosphate as a probe of the fidelity mechanisms of bacteriophage T4 DNA polymerase. D C Mace The Journal of biological chemistry 1984 pols set
Gap-filling DNA synthesis by HeLa DNA polymerase alpha in an in vitro base excision DNA repair scheme. D W Mosbaugh, Stuart Linn The Journal of biological chemistry 1984 new
The effect of the 3',5' thiophosphoryl linkage on the exonuclease activities of T4 polymerase and the Klenow fragment. A P Gupta, P A Benkovic, Stephen J Benkovic Nucleic acids research 1984 pols set
Method for determining whether a gene of Escherichia coli is essential: application to the polA gene. Catherine M Joyce, Nigel D F Grindley J Bacteriol 1984 new
Site specific mutagenesis: insertion of single noncomplementary nucleotides at specified sites by error-directed DNA polymerization. R A Zakour, E A James, Lawrence A Loeb Nucleic acids research 1984 new
Effect of glycerol and low pH on heat-induced cell killing and loss of cellular DNA polymerase activities in Chinese hamster ovary cells. N F Mivechi, W C Dewey Radiat Res 1984 new
Resistance in inhibitors of RNA polymerase in actinomycetes which produce them. M G Blanco, C Hardisson, J A Salas J Gen Microbiol 1984 pols set
Synthesis of catalytically active polymerase alpha by in vitro translation of calf RNA. S Detera-Wadleigh, E Karawya, Samuel H Wilson Advances in experimental medicine and biology 1984 new
The DNA polymerase-primase from drosophila melanogaster embryos. Rate and fidelity of polymerization on single-stranded DNA templates. Laurie S Kaguni, R A DiFrancesco, I. Robert Lehman The Journal of biological chemistry 1984 new
Structural and functional properties of DNA polymerase alpha from calf thymus. F Grummt, W Albert, G Zastrow, A Schnabel Adv Exp Med Biol 1984 new
Effect of temperature on transition and transversion mutagenesis: characterization of wild type and a mutator T4 DNA polymerase mutant. Linda J Reha-Krantz, S Parmaksizoglu Canadian journal of genetics and cytology. Journal canadien de génétique et de cytologie 1984 complete
DNA polymerase I and DNA primase complex in yeast. Paolo Plevani, G Badaracco, C Augl, L M Chang The Journal of biological chemistry 1984 topics set
Characteristic alteration in the nuclear DNA polymerase activity during the cell division cycle of Saccharomyces cerevisiae. E Tsuchiya, K Kimura, T Miyakawa, S Fukui Nucleic acids research 1984 pols set
[Studies on purification of HSV-2 induced DNA polymerase and its properties]. M B Yin, Z R Li, L J Xia, Y J Gao, Y Y Liu Zhongguo Yi Xue Ke Xue Yuan Xue Bao 1984 new
Comparative inhibition of DNA polymerases from varicella zoster virus (TK+ and TK-) strains by (E)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate. T Yokota, K Konno, S Shigeta, Erik De Clercq Molecular pharmacology 1984 new
Inhibition of cellular alpha DNA polymerase and herpes simplex virus-induced DNA polymerases by the triphosphate of BW759U. M H St Clair, W H Miller, R L Miller, C U Lambe, Phillip A Furman Antimicrob Agents Chemother 1984 new
Herpes simplex virus mutants resistant to arabinosyladenine in the presence of deoxycoformycin. H E Fleming, Donald M Coen Antimicrobial agents and chemotherapy 1984 new
Fine mapping and molecular cloning of mutations in the herpes simplex virus DNA polymerase locus. Donald M Coen, D P Aschman, P T Gelep, M J Retondo, Sandra K Weller, P A Schaffer Journal of virology 1984 new
Synthesis and antiviral properties of 5-vinylpyrimidine nucleoside analogs. Erik De Clercq, R T Walker Pharmacology & therapeutics 1984 new
On the molecular basis of transition mutations. Frequency of forming 2-aminopurine-cytosine base mispairs in the G X C----A X T mutational pathway by T4 DNA polymerase in vitro. D N Mhaskar, Myron F Goodman The Journal of biological chemistry 1984 topics set
Characterization of hepatitis B virus DNA polymerase. Y Goto, T Yamashita, M Arens, Tomonori Takahashi, T Hashimoto Jpn J Med Sci Biol 1984 new
Purification and characterization of a factor stimulating DNA polymerase alpha activity from mouse FM3A cells. K Kawasaki, K Nagata, Takemi Enomoto, Fumio Hanaoka, Masami Yamada J Biochem 1984 new
Delayed and reduced cell replication and diminishing levels of DNA polymerase-alpha in regenerating liver of aging mice. M Fry, J Silber, Lawrence A Loeb, G M Martin J Cell Physiol 1984 new
Intracellular localization and metabolism of DNA polymerase alpha in human cells visualized with monoclonal antibody. Hiroaki Nakamura, T Morita, S Masaki, Shonen Yoshida Exp Cell Res 1984 new
Aphidicolin, a specific inhibitor of DNA polymerase alpha, inhibits conversion of lanosterol to C-27 sterols in mouse L cells. D A Leonard, H W Chen The Journal of biological chemistry 1984 new
Characterization of an aphidicolin-resistant mutant of herpes simplex virus type 2 which induces an altered viral DNA polymerase. Yoshitaka Nishiyama, S Suzuki, M Yamauchi, K Maeno, Shonen Yoshida Virology 1984 new
Replication of M13mp7 single-stranded DNA in vitro by the 9-S DNA polymerase alpha from calf thymus. Frank Grosse, Gerhard Krauss Eur J Biochem 1984 new
Micromethod for phosphonoformate inhibition assay of hepatitis B viral DNA polymerase. H J Lin, P C Wu, C L Lai, W Chak Clin Chem 1984 new
Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS. R C Gallo, S Z Salahuddin, M Popovic, G M Shearer, M Kaplan, B F Haynes, T J Palker, R Redfield, J Oleske, B Safai Science 1984 new
Purification in a functional form of the terminal protein of Bacillus subtilis phage phi 29. I Prieto, José María Lázaro, J A García, José M Hermoso, Margarita Salas Proceedings of the National Academy of Sciences of the United States of America 1984 pols set
ATP and the processivity of Xenopus laevis DNA polymerase alpha. H D Riedel, H König, R Knippers Biochimica et biophysica acta 1984 pols set
Effect of spermine on interaction of DNA polymerase alpha from the loach (Misgurnus fossilis) eggs with DNA. V S Mikhailov, I M Androsova Biochimica et biophysica acta 1984 new
Synthesis of DNA polymerase by in vitro translation of calf RNA. S Detera-Wadleigh, E Karawya, Samuel H Wilson Biochem Biophys Res Commun 1984 new
A separate editing exonuclease for DNA replication: the epsilon subunit of Escherichia coli DNA polymerase III holoenzyme. R H Scheuermann, H Echols Proceedings of the National Academy of Sciences of the United States of America 1984 pols set
On the fidelity of DNA replication. The accuracy of T4 DNA polymerases in copying phi X174 DNA in vitro. Thomas A Kunkel, Lawrence A Loeb, Myron F Goodman The Journal of biological chemistry 1984 partial results
Novel interaction of aphidicolin with herpes simplex virus DNA polymerase and polymerase-associated exonuclease. K B Frank, D D Derse, K F Bastow, Yung-Chi Cheng The Journal of biological chemistry 1984 new
A role for DNA polymerase in the specificity of nucleotide incorporation opposite N-acetyl-2-aminofluorene adducts. S D Rabkin, B S Strauss Journal of molecular biology 1984 pols set
The excision of AP sites by the 3'-5' exonuclease activity of the Klenow fragment of Escherichia coli DNA polymerase I. V Bailly, W G Verly FEBS letters 1984 pols set
Misincorporation during DNA synthesis, analyzed by gel electrophoresis. G G Hillebrand, A H McCluskey, K A Abbott, G G Revich, K L Beattie Nucleic acids research 1984 new
Inhibitory effects of 1-beta-D-arabinofuranosyl-5-styryluracil 5'-triphosphates on DNA-dependent DNA polymerases alpha and beta from developing cherry salmon (Oncorhynchus masou) testes: on the approach to the selective affinity chromatography for DNA polymerase alpha. Shunji Izuta, Mineo Saneyoshi Nucleic Acids Symp Ser 1984 new
Mutagenic specificity of a novel T4 DNA polymerase mutant. Linda J Reha-Krantz, E M Liesner Genetics 1984 complete
DNA polymerase alpha inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes. T W Glover, C Berger, J Coyle, B Echo Hum Genet 1984 new
Butylphenyl dGTP: a selective and potent inhibitor of mammalian DNA polymerase alpha. N N Khan, George E Wright, L W Dudycz, Neal C Brown Nucleic acids research 1984 pols set
Mammalian DNA polymerase alpha holoenzymes with possible functions at the leading and lagging strand of the replication fork. H P Ottiger, Ulrich Hübscher Proceedings of the National Academy of Sciences of the United States of America 1984 pols set
Replication of phi X174 DNA by calf thymus DNA polymerase-alpha: measurement of error rates at the amber-16 codon. Frank Grosse, Gerhard Krauss, J W Knill-Jones, A R Fersht Adv Exp Med Biol 1984 new
[Purification and characterization of DNA polymerase alpha from Ehrlich ascites cells]. C C Qui, G Y Wu, Z K Wu Zhongguo Yi Xue Ke Xue Yuan Xue Bao 1984 new
[Immunofluorescent study of DNA polymerase alpha in rat cells and tissues]. V G Dëmin, V M Mikhaĭlov, Z I Uspenskaia, N V Tomilin, V M Bozhekov Tsitologiia 1984 new
[Relationship between serum HBV-DNA polymerase activity and HBe system: changes of DNA polymerase activity and transaminase]. S Saito, Satoshi Watanabe, A Yoshikawa, T Kamimura, F Ichida Nippon Shokakibyo Gakkai Zasshi 1984 new
Structural and functional properties of DNA polymerase delta from rabbit bone marrow. J J Byrnes Mol Cell Biochem 1984 new
Properties of the primase activity of the 9 S DNA polymerase alpha from calf thymus. Gerhard Krauss, Frank Grosse Adv Exp Med Biol 1984 new
Effects of ticlopidine, a new platelet antiaggregating agent, and its analogues on mitochondrial metabolism. Oxidative phosphorylation, protein synthesis and DNA polymerase activity. W H Abou-Khalil, L O Lim, A A Yunis, S Abou-Khalil Biochem Pharmacol 1984 new
Acyclovir triphosphate is a suicide inactivator of the herpes simplex virus DNA polymerase. Phillip A Furman, M H St Clair, T Spector The Journal of biological chemistry 1984 new
DNA primase from KB cells. Characterization of a primase activity tightly associated with immunoaffinity-purified DNA polymerase-alpha. Teresa S-F Wang, S Z Hu, D Korn The Journal of biological chemistry 1984 new
Activated cyclophosphamide: an enzyme-mechanism-based suicide inactivator of DNA polymerase/3'-5' exonuclease. L Bielicki, G Voelcker, H J Hohorst J Cancer Res Clin Oncol 1984 pols set
The biochemical basis of 5-bromouracil-induced mutagenesis. Heteroduplex base mispairs involving bromouracil in G x C----A x T and A x T----G x C mutational pathways. R S Lasken, Myron F Goodman The Journal of biological chemistry 1984 complete
Continuous assay for DNA polymerization by light scattering. Kenneth A Johnson, F R Bryant, Stephen J Benkovic Analytical biochemistry 1984 new
Conservation of molecular structure of DNA polymerase beta in vertebrates probed by tryptic peptide mapping. K Tanabe, Tsuyoshi Yamaguchi, Mineo Saneyoshi, Masamitsu Yamaguchi, Akio Matsukage, Tomonori Takahashi J Biochem 1984 new
Characteristics of the DNA polymerase beta-directed unscheduled DNA synthesis in isolated nuclei from adult rat liver. A Zoncheddu, R Accomando Int J Biochem 1984 new
DNA polymerase III holoenzyme of Escherichia coli: an asymmetric dimeric replicative complex containing distinguishable leading and lagging strand polymerases. Charles S McHenry, K O Johanson Adv Exp Med Biol 1984 pols set
Nucleoside triphosphate binding to DNA polymerase III holoenzyme of Escherichia coli. A direct photoaffinity labeling study. Subhasis B Biswas, Arthur Kornberg The Journal of biological chemistry 1984 pols set
Transfection of the DNA polymerase-alpha gene. P K Liu, Lawrence A Loeb Science (New York, N.Y.) 1984 new
Interaction of herpes simplex virus-induced DNA polymerase with 9-(1,3-dihydroxy-2-propoxymethyl)guanine triphosphate. K B Frank, J F Chiou, Yung-Chi Cheng The Journal of biological chemistry 1984 new
Replacement synthesis labeling of DNA molecules in vitro using the Escherichia coli exonuclease III/DNA polymerase I enzyme pair. C D James, I M Leffak Anal Biochem 1984 new
The DNA polymerase activity of vaccinia virus 'virosomes': solubilization and properties. F M Tomley, R J Cooper The Journal of general virology 1984 pols set
A new mechanism for the initiation of replication of phi 29 and adenovirus DNA: priming by the terminal protein. Margarita Salas Curr Top Microbiol Immunol 1984 pols set
Stereochemical course of the 3'----5'-exonuclease activity of DNA polymerase I. A P Gupta, Stephen J Benkovic Biochemistry 1984 new
Effect of 5-fluoro-2'-deoxyuridine and hydroxyurea on the phytohemagglutinin-induced increase of thymidine kinase, replicative DNA polymerase, deoxycytidylate deaminase and CDP reductase activities in human lymphocytes. G Tyrsted Mol Cell Biochem 1984 new
Characterization and purification of a phage phi 29-encoded DNA polymerase required for the initiation of replication. Luis Blanco, Margarita Salas Proceedings of the National Academy of Sciences of the United States of America 1984 partial results
Mammalian DNA polymerase alpha holoenzyme. Ulrich Hübscher, H P Ottiger Adv Exp Med Biol 1984 pols set
Identification of a higher molecular weight DNA polymerase alpha catalytic polypeptide in monkey cells by monoclonal antibody. E Karawya, J Swack, W Albert, J Fedorko, John D Minna, Samuel H Wilson Proceedings of the National Academy of Sciences of the United States of America 1984 new
Determination of the precise location and orientation of the Escherichia coli dnaE gene. D Shepard, R W Oberfelder, M M Welch, Charles S McHenry Journal of bacteriology 1984 new
N4-Methoxydeoxycytidine triphosphate is in the imino tautomeric form and substitutes for deoxythymidine triphosphate in primed poly d[A-T] synthesis with E. coli DNA polymerase I. B Singer, H Fraenkel-Conrat, L G Abbott, S J Spengler Nucleic acids research 1984 pols set
Cerebellar DNA polymerase activity in hypothyroid and malnourished rats. S J Muzzo, J A Brasel Am J Dis Child 1984 new
In vitro bypass of UV-induced lesions by Escherichia coli DNA polymerase I: specificity of nucleotide incorporation. S D Rabkin, P D Moore, B S Strauss Proceedings of the National Academy of Sciences of the United States of America 1983 pols set
Bacterial and phage mutations that reveal helix-unwinding activities required for bacteriophage T4 DNA replication. P Gauss, D H Doherty, L Gold Proceedings of the National Academy of Sciences of the United States of America 1983 complete
Affinity purification of bacteriophage T4 proteins essential for DNA replication and genetic recombination. T Formosa, R L Burke, B M Alberts Proceedings of the National Academy of Sciences of the United States of America 1983 complete
Mechanism of DNA Replication Catalyzed by Purifid T4 Replication Proteins (Book) 1983 complete
3,4-Dihydroxybenzylamine: an improved dopamine analog cytotoxic for melanoma cells in part through oxidation products inhibitory to dna polymerase. G B FitzGerald, M M Wick J Invest Dermatol 1983 new
[Isolation of two forms of DNA polymerase alpha from roe of loach. Physico-chemical properties of the isoenzymes]. V S Mikhaĭlov, D B Guliamov Biokhimiia 1983 new
DNA polymerase alpha cofactors C1C2 function as primer recognition proteins. C G Pritchard, D T Weaver, E F Baril, M L DePamphilis The Journal of biological chemistry 1983 new
Factors involved in the initiation of phage phi 29 DNA replication in vitro: requirement of the gene 2 product for the formation of the protein p3-dAMP complex. Luis Blanco, J A Garcìa, M A Peñalva, Margarita Salas Nucleic acids research 1983 new
Incorporation of 5-Aza-2'-deoxycytidine-5'-triphosphate into DNA. Interactions with mammalian DNA polymerase alpha and DNA methylase. J Bouchard, R L Momparler Mol Pharmacol 1983 pols set
Mutator versus antimutator activity of a T4 DNA polymerase mutant distinguishes two different frameshifting mechanisms. L S Ripley, B W Glickman, N B Shoemaker Mol Gen Genet 1983 complete
Two forms of the DNA polymerase of bacteriophage T7. M J Engler, R L Lechner, Charles C Richardson The Journal of biological chemistry 1983 partial results
Involvement of Escherichia coli K-12 DNA polymerase I in the growth of bacteriophage Mu. D L McBeth, A L Taylor J Virol 1983 new
In vitro DNA synthesis by an alpha-like DNA polymerase bound to replicating simian virus 40 chromosomes. M A Waqar, M J Evans, J F Burke, Y Tsubota, M J Plummer, J A Huberman J Virol 1983 new
Preliminary characterisation of inhibitors of DNA polymerase isolated from Xenopus laevis early embryos. C Smith, K McKune, R Cox, C Ford Biochimica et biophysica acta 1983 pols set
Metal content of DNA polymerase I purified from overproducing and wild type Escherichia coli. L J Ferrin, A S Mildvan, Lawrence A Loeb Biochem Biophys Res Commun 1983 new
DNA replication by novel macromolecular complexes involving DNA polymerase III holoenzyme activity. Y Kobayashi, K Kuratomi Biochem Biophys Res Commun 1983 new
A DNA topoisomerase activity copurifies with the DNA polymerase induced by herpes simplex virus. N Biswal, P Feldan, C C Levy Biochimica et biophysica acta 1983 new
Phosphonoformic acid-inhibitable nucleotide incorporation as a measure of hepatitis B viral DNA polymerase activity. H J Lin, J P Kwan, P C Wu, W Chak J Med Virol 1983 new
Acquisition of multiple nuclei and the activity of DNA polymerase alpha and reinitiation of DNA replication in terminally differentiated adult cardiac muscle cells in culture. W C Claycomb, H D Bradshaw Dev Biol 1983 new
Rose Bengal mediated inhibition of DNA polymerases: mechanism of inhibition of avian myeloblastosis virus reverse transcriptase under photooxidative conditions. S K Srivastava, Mukund J Modak Biochemistry 1983 new
The mechanism of inhibition of avian myeloblastosis virus reverse transcriptase by a dialdehyde derivative of ATP. Inactivation of essential sulfhydryl group function. S K Srivastava, K I Abraham, Mukund J Modak Biochimica et biophysica acta 1983 new
[Metabolic limitation of DNA-polymerase I synthesis by Escherichia coli strain CM5199]. S A Soktoev, E L Golovlev Mikrobiologiia 1983 new
A preformed, topologically stable replication fork. Characterization of leading strand DNA synthesis catalyzed by T7 DNA polymerase and T7 gene 4 protein. R L Lechner, Charles C Richardson The Journal of biological chemistry 1983 pols set
Photoaddition of 8-methoxypsoralen to E. coli DNA polymerase I. Role of psoralen photoadducts in the photosensitized alterations of pol I enzymatic activities. M Granger, C Hélène Photochem Photobiol 1983 pols set
Regulatory effect of aphidicolin on the activity of DNA polymerase alpha from mouse myeloma. K Ono, Y Iwata, H Nakane Biomed Pharmacother 1983 new
Improved conditions for activity gel analysis of DNA polymerase catalytic polypeptides. E Karawya, J A Swack, Samuel H Wilson Anal Biochem 1983 new
Immunocytochemical localization of chick DNA polymerases alpha and beta +. Akio Matsukage, S Yamamoto, Masamitsu Yamaguchi, M Kusakabe, Tetsuya Takahashi Journal of cellular physiology 1983 new
Resolution of the diadenosine 5',5"'-P1,P4-tetraphosphate binding subunit from a multiprotein form of HeLa cell DNA polymerase alpha. E Baril, P Bonin, D Burstein, K Mara, P Zamecnik Proceedings of the National Academy of Sciences of the United States of America 1983 new
On the enzymatic basis for mutagenesis by manganese. Myron F Goodman, S Keener, S Guidotti, E W Branscomb The Journal of biological chemistry 1983 topics set
Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). F Barré-Sinoussi, J C Chermann, F Rey, M T Nugeyre, S Chamaret, J Gruest, C Dauguet, C Axler-Blin, F Vézinet-Brun, C Rouzioux, W Rozenbaum, L Montagnier Science 1983 new
Excision repair and DNA synthesis with a combination of HeLa DNA polymerase beta and DNase V. D W Mosbaugh, Stuart Linn The Journal of biological chemistry 1983 new
Construction of a plasmid that overproduces the large proteolytic fragment (Klenow fragment) of DNA polymerase I of Escherichia coli. Catherine M Joyce, Nigel D F Grindley Proceedings of the National Academy of Sciences of the United States of America 1983 complete
T7-induced DNA polymerase. Requirement for thioredoxin sulfhydryl groups. S Adler, P Modrich The Journal of biological chemistry 1983 partial results
A DNA polymerase activity associated with the skeletal framework of the plasma membranes of a rat hepatoma. C S Shashikant, P K Srivastava, M R Das Biochem Biophys Res Commun 1983 new
Properties of purified enzymes induced by pathogenic drug-resistant mutants of herpes simplex virus. Evidence for virus variants expressing normal DNA polymerase and altered thymidine kinase. Brendan A Larder, D Derse, Yung-Chi Cheng, G Darby The Journal of biological chemistry 1983 new
Classification of DNA polymerase activities from ovaries of the frog, Xenopus laevis. E M Nelson, D J Stowers, M L Bayne, R M Benbow Dev Biol 1983 new
A DNA polymerase alpha partially resistant to aphidicolin in cells and embryos of Med-fly (Ceratitis capitata Wied.). A I Scovassi, R Cavalloro, U Bertazzoni Biochem Int 1983 new
Isolation of a yeast single-strand deoxyribonucleic acid binding protein that specifically stimulates yeast DNA polymerase I. S G LaBonne, L B Dumas Biochemistry 1983 new
Mouse teratocarcinoma cells resistant to aphidicolin and arabinofuranosyl cytosine: isolation and initial characterization. S Aizawa, Lawrence A Loeb, G M Martin Journal of cellular physiology 1983 new
Initiation of phage phi 29 DNA replication by the terminal protein modified at the carboxyl end. R P Mellado, Margarita Salas Nucleic acids research 1983 pols set
Template specificities of a RNA-directed DNA polymerase from a human homologous mixed mesodermal sarcoma. G B Weiss, B K Carr, E V Hannigan Oncology 1983 new
The dnaX gene encodes the DNA polymerase III holoenzyme tau subunit, precursor of the gamma subunit, the dnaZ gene product. M Kodaira, Subhasis B Biswas, Arthur Kornberg Mol Gen Genet 1983 new
The specificity of infidelity of DNA polymerase. L S Ripley Basic Life Sci 1983 topics set
Purification and characterization of two forms of DNA polymerase alpha from HeLa cell nuclei. Takemi Enomoto, S Tanuma, Masami Yamada Biochemistry 1983 new
[DNA polymerase of Epstein-Barr virus]. T Ooka Tanpakushitsu Kakusan Koso 1983 new
Evidence for a herpesvirus saimiri-specified DNA polymerase activity which is aphidicolin-resistant and phosphonoacetate-sensitive. P O'Hare, R W Honess The Journal of general virology 1983 new
DNA polymerase and simian virus 40 infection of resting monkey cells: induction of aphidicolin resistant alpha-polymerase. K Tanabe, E Karawya, J W Fewell, E L Kuff, Samuel H Wilson Nucleic acids research 1983 new
A novel DNA polymerase induced by Bacillus subtilis phage phi 29. K Watabe, J Ito Nucleic acids research 1983 new
Purification and immunological characterization of DNA polymerase-alpha from human acute lymphoblastic leukemia cells. F A Siddiqui Biochimica et biophysica acta 1983 new
Specific binding of the adenovirus terminal protein precursor-DNA polymerase complex to the origin of DNA replication. A W Rijnders, B G van Bergen, Peter C van der Vliet, J S Sussenbach Nucleic acids research 1983 new
Changes in DNA polymerase alpha, beta, gamma activities during early development of the teleost fish Misgurnus fossilis (loach). V S Mikhailov, D B Gulyamov Eur J Biochem 1983 new
Genetic analysis of temperature-sensitive mutants of HSV-1: the combined use of complementation and physical mapping for cistron assignment. Sandra K Weller, D P Aschman, W R Sacks, Donald M Coen, P A Schaffer Virology 1983 new
The gene 4 protein of bacteriophage T7. Characterization of helicase activity. S W Matson, Stanley Tabor, Charles C Richardson The Journal of biological chemistry 1983 pols set
Association of DNA primase with the beta/gamma subunits of DNA polymerase alpha from Drosophila melanogaster embryos. Laurie S Kaguni, J M Rossignol, R C Conaway, G R Banks, I. Robert Lehman The Journal of biological chemistry 1983 new
Inhibition by interferon of herpes simplex virus thymidine kinase and DNA polymerase in infected and biochemically transformed cells. A Panet, H Falk The Journal of general virology 1983 new
Crystallization and 7 A resolution electron density map of the large fragment of Escherichia coli DNA polymerase I. P Brick, D Ollis, Thomas A Steitz Journal of molecular biology 1983 pols set
Uracil in deoxyribonucleotide polymers reduces their template-primer activity for E. coli DNA polymerase I. J A Vilpo, J Ridell Nucleic acids research 1983 pols set
Crystallographic studies of protein-nucleic acid interaction: catabolite gene activator protein and the large fragment of DNA polymerase I. Thomas A Steitz, I T Weber, D Ollis, P Brick Journal of biomolecular structure & dynamics 1983 new
Specific inhibitors of eukaryotic DNA synthesis and DNA polymerase alpha, 3-deoxyaphidicolin and aphidicolin-17-monoacetate. T Haraguchi, M Oguro, H Nagano, A Ichihara, S Sakamura Nucleic acids research 1983 new
Mammalian mutator mutant with an aphidicolin-resistant DNA polymerase alpha. P K Liu, C C Chang, J E Trosko, D K Dube, G M Martin, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1983 new
The in vitro inhibition of DNA polymerase alpha and avian reverse transcriptase by novobiocin. L Sarih, M Garret, H Aoyama, P V Graves, L Tarrago-Litvak, Simon Litvak Biochem Int 1983 new
Influence of local nucleotide sequence on substitution of 2-aminopurine for adenine during deoxyribonucleic acid synthesis in vitro. R C Pless, M J Bessman Biochemistry 1983 complete
Effects of bisulfite (sulfur dioxide) on DNA synthesis and fidelity by DNA polymerase I. R G Mallon, T G Rossman Chem Biol Interact 1983 pols set
Inhibition of DNA polymerase-alpha from rat hepatoma with a series of new synthetic polynucleotides. Z R Li, Y K Ho, T J Bardos Cancer Biochem Biophys 1983 new
Accuracy of DNA polymerase-alpha in copying natural DNA. Frank Grosse, Gerhard Krauss, J W Knill-Jones, A R Fersht The EMBO journal 1983 new
Use of T4 DNA polymerase replacement synthesis for specific labeling of plasmid-cloned inserts. K C Deen, T A Landers, M Berninger Anal Biochem 1983 pols set
The 3'-5' proofreading exonuclease of bacteriophage T4 DNA polymerase is stimulated by other T4 DNA replication proteins. P Bedinger, B M Alberts The Journal of biological chemistry 1983 partial results
[DNA polymerase gamma in the cells of loach embryos localized in mitochondria]. V S Mikhaĭlov, D B Guliamov, A V Peskin, L S Filatova Biokhimiia 1983 new
Subspecies of DNA polymerase alpha from calf thymus with different fidelity in copying synthetic template-primers. S Brosius, Frank Grosse, Gerhard Krauss Nucleic acids research 1983 new
Identification of the epsilon-subunit of Escherichia coli DNA polymerase III holoenzyme as the dnaQ gene product: a fidelity subunit for DNA replication. R Scheuermann, S Tam, Peter M J Burgers, Chengping Lu, H Echols Proceedings of the National Academy of Sciences of the United States of America 1983 pols set
The cycling of Escherichia coli DNA polymerase III holoenzyme in replication. Peter M J Burgers, Arthur Kornberg The Journal of biological chemistry 1983 partial results
On the fidelity of DNA replication. Mechanisms of misincorporation by intercalating agents. C W Shearman, M M Forgette, Lawrence A Loeb The Journal of biological chemistry 1983 new
Infidelity of DNA synthesis as a cause of mutagenesis. Lawrence A Loeb, P K Liu, S K Das, J R Silber Princess Takamatsu symposia 1983 new
Inhibition of terminal deoxynucleotidyltransferase by (E)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate. K Ono, H Nakane, L Colla, Erik De Clercq Nucleic acids symposium series 1983 new
Elementary steps in the DNA polymerase I reaction pathway. F R Bryant, Kenneth A Johnson, Stephen J Benkovic Biochemistry 1983 pols set
Detection of enzymatic activities in sodium dodecyl sulfate-polyacrylamide gels: DNA polymerases as model enzymes. A Blank, J R Silber, M P Thelen, C A Dekker Anal Biochem 1983 new
Chemical inactivation of hepatitis B virus: the effect of disinfectants on virus-associated DNA polymerase activity, morphology and infectivity. C R Howard, J Dixon, P Young, P van Eerd, H Schellekens J Virol Methods 1983 new
Influences of anionic polysaccharides on DNA synthesis in isolated nuclei and by DNA polymerase alpha: correlation of observed effects with properties of the polysaccharides. K Furukawa, V P Bhavanandan Biochimica et biophysica acta 1983 new
Genetic characterization of early amber mutations in the Escherichia coli polA gene and purification of the amber peptides. W S Kelley, Catherine M Joyce Journal of molecular biology 1983 new
Characterization of messenger RNA for chick-embryo DNA polymerase beta and its translation product in vitro. Masamitsu Yamaguchi, Tomonori Takahashi, K Yasuda, Y Shimura, Akio Matsukage Eur J Biochem 1983 new
Excess beta subunit can bypass the ATP requirement for highly processive synthesis by the Escherichia coli DNA polymerase III holoenzyme. J J Crute, R J LaDuca, K O Johanson, Charles S McHenry, Robert A Bambara The Journal of biological chemistry 1983 pols set
Testosterone stimulation of DNA-dependent DNA polymerase activities in the cloacal and uropygial glands of the male quail (Coturnix coturnix japonica). J H Abalain, Y Amet, J Y Daniel, H H Floch Gen Comp Endocrinol 1983 new
Reactions in vitro of the DNA polymerase-primase from Xenopus laevis eggs. A role for ATP in chain elongation. H König, H D Riedel, R Knippers Eur J Biochem 1983 pols set
5-methyltetrahydrofolate-related enzymes and DNA polymerase alpha in normal and malignant hematopoietic cells. Y Kano, S Sakamoto, K Hida, K Suda, F Takaku Eur J Cancer Clin Oncol 1983 new
A novel single-stranded DNA-binding protein from the Novikoff hepatoma which stimulates DNA polymerase beta. Purification and general characterization. T J Koerner, R R Meyer The Journal of biological chemistry 1983 new
Mutations in the herpes simplex virus DNA polymerase gene conferring hypersensitivity to aphidicolin. Donald M Coen, Phillip A Furman, D P Aschman, P A Schaffer Nucleic acids research 1983 new
DNA primase associated with 10 S DNA polymerase alpha from calf thymus. Shonen Yoshida, R Suzuki, S Masaki, Osamu Koiwai Biochimica et biophysica acta 1983 new
Site-specific pausing of deoxyribonucleic acid synthesis catalyzed by four forms of Escherichia coli DNA polymerase III. R J LaDuca, P J Fay, C Chuang, Charles S McHenry, Robert A Bambara Biochemistry 1983 pols set
Selection for temperature-sensitive mutations in specific vaccinia virus genes: isolation and characterization of a virus mutant which encodes a phosphonoacetic acid-resistant, temperature-sensitive DNA polymerase. P Sridhar, R C Condit Virology 1983 new
Induction of Epstein-Barr virus antigens and DNA-polymerase activities in P3HR-1 cell line and its subline passaged in the presence of phosphonoformate. K Prachová, J Roubal, V Vonka, B Brichácek, M Reifová Acta Virol 1983 new
Mechanism of o-phenanthroline mediated inhibition of E. coli DNA polymerase I : formation of template-primer-metal-phenanthroline complexes with resultant loss of catalytic activity. K I Abraham, Mukund J Modak Biochem Biophys Res Commun 1983 pols set
DNA-dependent nucleoside 5'-triphosphatase activity of the gene 4 protein of bacteriophage T7. S W Matson, Charles C Richardson The Journal of biological chemistry 1983 pols set
Influence of amino acid deficiency and tRNA aminoacylation on DNA synthesis and DNA polymerase activity during the secondary immune response in vitro. G Taudou, J Wiart, J Panijel Mol Immunol 1983 new
Evidence for an altered adenovirus DNA polymerase in cells infected with the mutant H5ts149. B R Friefeld, J H Lichy, Jerard Hurwitz, M S Horwitz Proceedings of the National Academy of Sciences of the United States of America 1983 new
Characterization of human cytomegalovirus-induced DNA polymerase and the associated 3'-to-5', exonuclease. Yoshitaka Nishiyama, K Maeno, Shonen Yoshida Virology 1983 new
Purified DNA polymerase gamma replicates bovine parvovirus DNA to a unit-length product. A T Robertson, R C Bates, E R Stout Biochem Biophys Res Commun 1983 new
Retrostatin, a new specific enzyme inhibitor against avian myeloblastosis virus reverse transcriptase. M Nishio, A Kuroda, Motoshi Suzuki, K Ishimaru, Shinichiro Nakamura, R Nomi The Journal of antibiotics 1983 new
Baculovirus replication: inhibition of Trichoplusia ni multiple nuclear polyhedrosis virus by [E]-5-(2-bromovinyl)-2'-deoxyuridine. Xin Wang, T Lescott, Erik De Clercq, D C Kelly The Journal of general virology 1983 new
The elongation of mismatched primers by DNA polymerase alpha from calf thymus. B Reckmann, Frank Grosse, Gerhard Krauss Nucleic acids research 1983 new
A helix-destabilising protein from herpes simplex virus type I infected cells which specifically stimulates the virus induced DNA polymerase activity in vitro. C B Bruce, C K Pearson Biochem Biophys Res Commun 1983 new
Mutator strains of Escherichia coli, mutD and dnaQ, with defective exonucleolytic editing by DNA polymerase III holoenzyme. H Echols, Chengping Lu, Peter M J Burgers Proceedings of the National Academy of Sciences of the United States of America 1983 new
Infidelity of DNA synthesis associated with bypass of apurinic sites. Roel M Schaaper, Thomas A Kunkel, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1983 pols set
Kinetics of base misinsertion by DNA polymerase I of Escherichia coli. A R Fersht, J P Shi, W C Tsui Journal of molecular biology 1983 topics set
Identification of DNA polymerase(s) involved in the repair of viral and cellular DNA in herpes simplex virus type 2-infected cells. Yoshitaka Nishiyama, Tatsuya Tsurumi, H Aoki, K Maeno Virology 1983 new
[Eukaryotic 3' leads to 5'-exonuclease correcting DNA-polymerase errors]. V M Krutiakov, N V Beliakova, N E Kleĭner, O K Legina, Igor V Shevelev Dokl Akad Nauk SSSR 1983 new
A simple and very efficient method for generating cDNA libraries. U Gubler, B J Hoffman Gene 1983 pols set
Preparation of DNA polymerase alpha X C1C2 by reconstituting DNA polymerase alpha with its specific stimulatory cofactors, C1C2. C G Pritchard, M L DePamphilis The Journal of biological chemistry 1983 new
Relationship between HBV-specific DNA polymerase and HBe antigen/antibody system in chronic HBV infection: factors determining selection of patients and outcome of antiviral therapy. A Craxi, I V Weller, M F Bassendine, M J Fowler, J Monjardino, H C Thomas, S Sherlock Gut 1983 new
Isolation of an intact DNA polymerase-primase from embryos of Drosophila melanogaster. Laurie S Kaguni, J M Rossignol, R C Conaway, I. Robert Lehman Proceedings of the National Academy of Sciences of the United States of America 1983 new
DNA polymerase function in repair synthesis in human fibroblasts. S L Dresler, M W Lieberman Princess Takamatsu Symp 1983 new
Adenovirus DNA replication in vitro: synthesis of full-length DNA with purified proteins. K Nagata, R A Guggenheimer, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1983 new
Bacteriophage T7 DNA replication. Synthesis of lagging strands in a reconstituted system using purified proteins. M J Engler, Charles C Richardson The Journal of biological chemistry 1983 pols set
The fidelity of mouse liver mitochondrial DNA polymerase following long-term administration of carbon tetrachloride, diethylnitrosamine, or phenobarbital. L S Mulcahy, J H Gans Mol Pharmacol 1983 new
Trimethoprim-induced DNA polymerase I deficiency in Escherichia coli K-12. P Mukhopadhyay, U Syrowik, S Palchaudhuri J Bacteriol 1983 new
Effect of hyperthermia on the survival of normal human peripheral blood mononuclear cells. S S Agarwal, E J Katz, Lawrence A Loeb Cancer research 1983 new
[Dependence of DNA-polymerase I supersynthesis on the specific growth rate of Escherichia coli CM 5199]. E L Golovlev, A N Shkidchenko, S A Soktoev, L V Gurina Dokl Akad Nauk SSSR 1983 pols set
Full and empty particles of hepatitis B virus in hepatocytes from patients with HBsAg-positive chronic active hepatitis. Y Sakamoto, G Yamada, M Mizuno, T Nishihara, S Kinoyama, T Kobayashi, Tomonori Takahashi, H Nagashima Laboratory investigation; a journal of technical methods and pathology 1983 new
Interaction of a DNA-binding protein, the product of gene D5 of bacteriophage T5, with double-stranded DNA: effects on T5 DNA polymerase functions in vitro. R K Fujimura, B C Roop J Virol 1983 new
[Processing and some properties of DNA-polymerase alpha from sea urchin embryos]. L L Terent'ev, N A Terent'eva, V A Rasskazov Biokhimiia 1983 new
On the fidelity of DNA replication. Specificity of nucleotide substitution by intercalating agents. C W Shearman, Lawrence A Loeb The Journal of biological chemistry 1983 pols set
Properties of the T4 bacteriophage DNA replication apparatus: the T4 dda DNA helicase is required to pass a bound RNA polymerase molecule. P Bedinger, M Hochstrasser, C V Jongeneel, B M Alberts Cell 1983 complete
The mammalian primase is part of a high molecular weight DNA polymerase alpha polypeptide. Ulrich Hübscher The EMBO journal 1983 new
[DNA binding proteins and DNA polymerase stimulating factors of eukaryotic cells]. Yoh Watanabe, Fumio Hanaoka, Masami Yamada Tanpakushitsu Kakusan Koso 1983 new
Antiviral activity of the 3'-amino derivative of (E)-5-(2-bromovinyl)-2'-deoxyuridine. Erik De Clercq, J Descamps, Jan Balzarini, T Fukui, H S Allaudeen The Biochemical journal 1983 new
Selective inactivation of the 3' to 5' exonuclease activity of Escherichia coli DNA polymerase I by heat. P J Lecomte, O P Doubleday Nucleic acids research 1983 pols set
Contribution of 3' leads to 5' exonuclease activity of DNA polymerase III holoenzyme from Escherichia coli to specificity. A R Fersht, J W Knill-Jones Journal of molecular biology 1983 pols set
Characterization of strand displacement synthesis catalyzed by bacteriophage T7 DNA polymerase. R L Lechner, M J Engler, Charles C Richardson The Journal of biological chemistry 1983 partial results
Localization of DNA polymerase alpha on the nuclear membrane in sea urchin embryos. M Shioda, H Nagano Exp Cell Res 1983 new
In vitro and in vivo studies of Trypanosoma cruzi DNA polymerase. A Solari, D Tharaud, Y Repetto, J Aldunate, A Morello, Simon Litvak Biochem Int 1983 pols set
Depurination-induced infidelity of deoxyribonucleic acid synthesis with purified deoxyribonucleic acid replication proteins in vitro. Thomas A Kunkel, Roel M Schaaper, Lawrence A Loeb Biochemistry 1983 new
Tight association of DNA primase with a subspecies of mouse DNA polymerase alpha. T Yagura, Shigeru Tanaka, T Kozu, T Seno, D Korn The Journal of biological chemistry 1983 new
The incorporation of O6-methyldeoxyguanosine and O4-methyldeoxythymidine monophosphates into DNA by DNA polymerases I and alpha. J A Hall, R Saffhill Nucleic acids research 1983 topics set
Novel form of DNA polymerase alpha associated with DNA primase activity of vertebrates. Detection with mouse stimulating factor. T Yagura, T Kozu, T Seno, Mineo Saneyoshi, Shin-Ichiro Hiraga, H Nagano The Journal of biological chemistry 1983 new
Dynamic domains of DNA polymerase alpha in regenerating rat liver. H C Smith, R Berezney Biochemistry 1983 new
Escherichia coli polymerase I can use O2-methyldeoxythymidine or O4-methyldeoxythymidine in place of deoxythymidine in primed poly(dA-dT).poly(dA-dT) synthesis. B Singer, J Sági, J T Kuśmierek Proceedings of the National Academy of Sciences of the United States of America 1983 pols set
The effect of retroviral transformation on DNA replication and DNA polymerase-gamma activity in chick embryo fibroblast mitochondria. M A D'Agostino, M M Nass Exp Cell Res 1983 new
Gel filtration of a complex of DNA polymerase and DNA precursor-synthesizing enzymes from a human lymphoblastoid cell line. R G Wickremasinghe, J C Yaxley, A V Hoffbrand Biochimica et biophysica acta 1983 new
A major role for bacteriophage T4 DNA polymerase in frameshift mutagenesis. L S Ripley, N B Shoemaker Genetics 1983 topics set
A cellular factor involved in the formation of a DNA-synthesizing complex from DNA polymerase I in Escherichia coli. R Scharff, M A Hanson, R W Hendler Biochimica et biophysica acta 1983 new
Products of DNA cleavage by the 1,10-phenanthroline-copper complex. Inhibitors of Escherichia coli DNA polymerase I. L M Pope, K A Reich, D R Graham, D S Sigman The Journal of biological chemistry 1982 pols set
DNA polymerase-alpha. Common polypeptide core structure of three enzyme forms from human KB cells. D Filpula, Paul A Fisher, D Korn The Journal of biological chemistry 1982 new
5-Methyltetrahydrofolate related enzymes and DNA polymerase alpha activities in bone marrow cells from patients with vitamin B12 deficient megaloblastic anemia. Y Kano, S Sakamoto, K Hida, K Suda, F Takaku Blood 1982 new
Purification involving polymin P fractionation of Escherichia coli DNA polymerase III which shows a high sedimentation constant. Y Kobayashi, K Kuratomi FEBS letters 1982 pols set
Specific sequences in native DNA that arrest synthesis by DNA polymerase alpha. D T Weaver, M L DePamphilis The Journal of biological chemistry 1982 new
Allosteric inhibition by aphidicolin of the activity of DNA polymerase alpha from mouse myeloma. K Ono, Y Iwata, H Nakane Nucleic Acids Symp Ser 1982 new
Coincidence of subnuclear distribution of poly(ADP-ribose) synthetase and DNA polymerase beta in nuclei of normal and regenerating liver. E Kirsten, T Minaga, E Kun FEBS letters 1982 new
Oligothymidylate analogues having stereoregular, alternating methylphosphonate/phosphodiester backbones as primers for DNA polymerase. P S Miller, N D Annan, K B McParland, S M Pulford Biochemistry 1982 pols set
Synthesis by the DNA primase of Drosophila melanogaster of a primer with a unique chain length. R C Conaway, I. Robert Lehman Proceedings of the National Academy of Sciences of the United States of America 1982 new
Template-prime-dependent turnover of (Sp)-dATP alpha S by T4 DNA polymerase. The stereochemistry of the associated 3' goes to 5'-exonuclease. A Gupta, C DeBrosse, Stephen J Benkovic The Journal of biological chemistry 1982 topics set
Meiosis in Coprinus: characterization and activities of two forms of DNA polymerase during meiotic stages. Kengo Sakaguchi, B C Lu Molecular and cellular biology 1982 new
The role of DNA polymerase in base substitution mutagenesis on non-instructional templates. Bernard Strauss, S Rabkin, D Sagher, P Moore Biochimie 1982 pols set
Characterization of the homopolymer tailing reaction catalyzed by terminal deoxynucleotidyl transferase. Implications for the cloning of cDNA. A M Michelson, S H Orkin The Journal of biological chemistry 1982 partial results
HBV-associated DNA polymerase activity in plasmas from HBsAg carriers in Taiwan.--A preliminary report. L W Lai, L C Hsu, W T Liu, D S Chen, J Y Chen, C S Yang Taiwan Yi Xue Hui Za Zhi 1982 new
Studies on the mechanism of Escherichia coli DNA polymerase I large fragment. Chain termination and modulation by polynucleotides. S D Detera, Samuel H Wilson The Journal of biological chemistry 1982 pols set
Inhibition of a novel subspecies of DNA polymerase alpha by 2'-deoxy-2'-azidoadenosine 5'-triphosphate. T Yagura, T Kozu, I Seno, T Nishijima, E Ohtsuka, M Ikehara Biochem Biophys Res Commun 1982 new
Chick embryo DNA polymerase alpha. Polypeptide components and their microheterogeneity. Masamitsu Yamaguchi, K Tanabe, Tomonori Takahashi, Akio Matsukage The Journal of biological chemistry 1982 new
Isolation of the catalytic core of DNA polymerase alpha from rabbit bone marrow. L P Goscin, J J Byrnes Nucleic acids research 1982 new
Template-directed pausing in in vitro DNA synthesis by DNA polymerase a from Drosophila melanogaster embryos. Laurie S Kaguni, D A Clayton Proceedings of the National Academy of Sciences of the United States of America 1982 new
Evidence that a critical threshold of DNA polymerase-alpha activity may be required for the initiation of DNA synthesis in mammalian cell heterokaryons. W R Pendergrass, A C Saulewicz, G C Burmer, P S Rabinovitch, Thomas H Norwood, G M Martin J Cell Physiol 1982 new
[Effect of the antitumor antibiotic bleomycin on DNA polymerase activity]. S N Naryzhnyĭ, Igor V Shevelev, V M Krutiakov Biokhimiia 1982 new
Activation of DNA polymerase beta in isolated nuclei. S Chanpu, D Werner Biochem Biophys Res Commun 1982 new
Studies on catalytic subunits of mouse myeloma alpha-polymerase. E M Karawya, Samuel H Wilson The Journal of biological chemistry 1982 new
Photodynamic inhibition of Escherichia coli DNA polymerase I by 8-methoxypsoralen plus near ultraviolet irradiation. M Granger, F Toulme, C Hélène Photochem Photobiol 1982 pols set
Altered sensitivity to 1-beta-D-arabinofuranosylcytosine 5'-triphosphate of DNA polymerase alpha from leukemic blasts of acute lymphoblastic leukemia. M TAnaka, Shonen Yoshida Cancer research 1982 new
Recombinational bypass of pyrimidine dimers promoted by the recA protein of Escherichia coli. Zvi Livneh, I. Robert Lehman Proceedings of the National Academy of Sciences of the United States of America 1982 new
Unscheduled DNA synthesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Hela cells. K Yamada, H Kato, Fumio Hanaoka, Masami Yamada Gann = Gan 1982 new
DNA-dependent ATPase B of FM3A cells. Its separation from DNA polymerase alpha. Yoh Watanabe, K Nagata, Y Tawaragi, Takemi Enomoto, Fumio Hanaoka, Masami Yamada FEBS letters 1982 new
Stereochemical course of nucleotidyl transfer catalyzed by bacteriophage T7 induced DNA polymerase. R S Brody, S Adler, P Modrich, W J Stec, Z J Leznikowski, P A Frey Biochemistry 1982 new
Priming of DNA synthesis by diadenosine 5',5"'-P1,P4-tetraphosphate with a double-stranded octadecamer as a template and DNA polymerase alpha. P C Zamecnik, E Rapaport, E F Baril Proceedings of the National Academy of Sciences of the United States of America 1982 new
The adaptive response to alkylating agents: the removal of O6-methylguanine from DNA is not dependent on DNA polymerase-1. Peter Karran, S Stevens, B Sedgwick Mutation research 1982 new
Effect of post-treatment with aphidicolin - a specific inhibitor of DNA polymerase alpha - on sister-chromatid exchanges induced by ethyl methanesulfonate. Y Nishi, M M Hasegawa, N Inui, S Ikegami, Masami Yamada Mutation research 1982 new
The beta subunit of the DNA polymerase III holoenzyme becomes inaccessible to antibody after formation of an initiation complex with primed DNA. K O Johanson, Charles S McHenry The Journal of biological chemistry 1982 new
A third DNA polymerase from Spiroplasma citri and two other spiroplasmas. A Charron, Michel Castroviejo, C Bebear, J Latrille, J M Bove J Bacteriol 1982 new
Inhibitory effect of E-5-(2-bromovinyl)-1-beta-D-arabinofuranosyluracil on herpes simplex virus replication and DNA synthesis. J Descamps, R K Sehgal, Erik De Clercq, H S Allaudeen Journal of virology 1982 new
Tryptophanyl-tRNA synthetase is found closely associated with an stimulates DNA polymerase alpha-like activity from wheat embryos. Michel Castroviejo, M Fournier, M Gatius, J C Gandar, B Labouesse, Simon Litvak Biochem Biophys Res Commun 1982 new
DNA polymerase and thymidine kinase activities in MC-29 virus-induced transplantable hepatoma and the effect of cytostatic treatment of these activities. M Staub, T Szpaszokukockaja, M Bencsáth, F Antoni, K Lapis Chem Biol Interact 1982 new
Cloning and identification of the product of the dnaE gene of Escherichia coli. M M Welch, Charles S McHenry Journal of bacteriology 1982 new
Purification of an adenovirus-coded DNA polymerase that is required for initiation of DNA replication. B W Stillman, F Tamanoi, M B Mathews Cell 1982 new
[Molecular mechanisms of stabilization and preparation of metabolic breaks in DNA strands in vivo. I. Tandem action of exonuclease V and DNA polymerase II]. G E Fradkin, O A Aĭzenberg, L A Naumova Mol Biol (Mosk) 1982 new
In vitro conversion of MVM parvovirus single-stranded DNA to the replicative form by DNA polymerase alpha from Ehrlich ascites tumour cells. E A Faust, C D Rankin Nucleic acids research 1982 new
Size classes of products synthesized processively by two subassemblies of Escherichia coli DNA polymerase III holoenzyme. P J Fay, K O Johanson, Charles S McHenry, Robert A Bambara The Journal of biological chemistry 1982 pols set
Purification and characterization of a DNA polymerase-template complex in mouse ascites tumor cells. S J Wu, S X Xiao Sci Sin B 1982 new
Inhibition of murine leukaemia virus reverse transcriptase by 2-halogenated polyadenylic acids. T Fukui, Erik De Clercq The Biochemical journal 1982 new
DNA polymerase requirements for parvovirus H-1 DNA replication in vitro. R Kollek, B Y Tseng, Mehran Goulian J Virol 1982 pols set
DNA primase activity associated with DNA polymerase alpha from Xenopus laevis ovaries. M Shioda, E M Nelson, M L Bayne, R M Benbow Proceedings of the National Academy of Sciences of the United States of America 1982 pols set
Changes in intracellular location of DNA polymerase-alpha during oocyte maturation of the toad, Bufo bufo japonicus. H Nagano, K Okano, S Ikegami, C Katagiri Biochem Biophys Res Commun 1982 new
Tetrahymena alpha-type DNA polymerase A: purification and subunit analysis. A Sakai, Yoh Watanabe J Biochem 1982 new
Nucleotide sequence of the Escherichia coli polA gene and primary structure of DNA polymerase I. Catherine M Joyce, W S Kelley, Nigel D F Grindley The Journal of biological chemistry 1982 complete
10 S DNA polymerase alpha of calf thymus shows a microheterogeneity in its large polypeptide component. S Masaki, Osamu Koiwai, Shonen Yoshida The Journal of biological chemistry 1982 new
Terminal deoxynucleotidyl transferase help DNA polymerase alpha bypass thymine dimer. Shonen Yoshida, S Masaki, Hiroaki Nakamura, T Morita Adv Exp Med Biol 1982 new
Specificity of the catalytic interaction of human DNA polymerase beta with nucleic acid substrates. Teresa S-F Wang, D Korn Biochemistry 1982 pols set
[Isolation and properties of DNA polymerase from the extreme thermophilic bacterium Thermus ruber]. A S Kaledin, A G Sliusarenko, S I Gorodetskiĭ Biokhimiia 1982 new
Correlations between the activities of DNA polymerase alpha and the glucocorticoid receptor. T J Schmidt, F J Bollum, G Litwack Proceedings of the National Academy of Sciences of the United States of America 1982 new
Characterization of the DNA polymerases induced by a group of herpes simplex virus type I variants selected for growth in the presence of phosphonoformic acid. D Derse, K F Bastow, Yuan Cheng The Journal of biological chemistry 1982 new
Mouse DNA replicase. DNA polymerase associated with a novel RNA polymerase activity to synthesize initiator RNA of strict size. T Yagura, T Kozu, T Seno The Journal of biological chemistry 1982 new
Caffeine inhibits DNA polymerase I from Escherichia coli: studies in vitro. R Balachandran, A Srinivasan Carcinogenesis 1982 pols set
Inactivation of DNA-polymerase associated with hepatitis B virus. N Nath, C T Fang, R Y Dodd J Med Virol 1982 new
Ethidium bromide stimulation of DNA polymerase activity by stabilization of the primer-template duplex. Michel Castroviejo, P V Graves, D Tharaud, E Hevia-Campos, Simon Litvak Biochimie 1982 new
Adenoviral protein-primed initiation of DNA chains in vitro. J E Ikeda, Takemi Enomoto, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1982 new
Transient generation of displaced single-stranded DNA during nick translation. R C Lundquist, B M Olivera Cell 1982 pols set
A study of the mechanism of T4 DNA polymerase with diastereomeric phosphorothioate analogues of deoxyadenosine triphosphate. P J Romaniuk, F Eckstein The Journal of biological chemistry 1982 pols set
Inhibition of eukaryotic DNA polymerase-alpha by polydeoxynucleotides. M Oguro, H Nagano J Biochem 1982 new
Inhibition in vitro of yeast DNA polymerase I activity by beta-blockers. M Presta, L Riboni, G Ragnotti Biosci Rep 1982 pols set
Tumor-induced impairment of T-cell-independent B-cell blastogenesis and DNA polymerase activity. W L Farrar, K D Elgert, C J Burger Proc Soc Exp Biol Med 1982 new
Genetic evidence for vaccinia virus-encoded DNA polymerase: isolation of phosphonoacetate-resistant enzyme from the cytoplasm of cells infected with mutant virus. B Moss, N Cooper J Virol 1982 new
A mammalian DNA polymerase alpha holoenzyme functioning on defined in vivo-like templates. Ulrich Hübscher, P Gerschwiler, G K McMaster The EMBO journal 1982 topics set
Intracellular localization of human DNA polymerase alpha with monoclonal antibodies. K G Bensch, Shigeru Tanaka, S Z Hu, Teresa S-F Wang, D Korn The Journal of biological chemistry 1982 pols set
Rose Bengal mediated inhibition of DNA polymerases: mechanism of inhibition of avian myeloblastosis virus reverse transcriptase under nonoxidative conditions. S K Srivastava, Mukund J Modak Biochemistry 1982 new
Studies on ehrlich ascites tumour cells: DNA synthesis, and template activity of chromatin for DNA polymerase. R B Baghdjian, S Itzhaki, C H Ockey, R F Itzhaki Mol Cell Biochem 1982 new
ATP activation of DNA polymerase III holoenzyme from Escherichia coli. II. Initiation complex: stoichiometry and reactivity. Peter M J Burgers, Arthur Kornberg The Journal of biological chemistry 1982 pols set
A fully active DNA polymerase I from Escherichia coli lacking stoichiometric zinc. K E Walton, P C FitzGerald, M S Herrmann, W D Behnke Biochem Biophys Res Commun 1982 pols set
An improved purification method and a physical characterization of phage T7 DNA polymerase. H Randahl, I Slabý, A Holmgren Eur J Biochem 1982 pols set
The effect of benzo[a]pyrene on DNA synthesis and DNA polymerase activity of rat liver mitochondria. I Salazar, L Tarrago-Litvak, L Gil, Simon Litvak FEBS letters 1982 new
Immunological comparison of purified DNA polymerase alpha from embryos of Drosophila melanogaster with forms of the enzyme present in vivo. B Sauer, I. Robert Lehman The Journal of biological chemistry 1982 new
Deoxyribonucleic acid dependent adenosinetriphosphatases from the Novikoff hepatoma. Characterization of a homogeneous adenosinetriphosphatase that stimulates DNA polymerase beta. D C Thomas, R R Meyer Biochemistry 1982 new
Initiation of phage phi 29 DNA replication in vitro: formation of a covalent complex between the terminal protein, p3, and 5'-dAMP. M A Peñalva, Margarita Salas Proceedings of the National Academy of Sciences of the United States of America 1982 partial results
Differential incorporation of thymidylate analogues into DNA by DNA polymerase alpha and by DNA polymerases specified by two herpes simplex viruses. L Kowalzick, K K Gauri, Silvio Spadari, G Pedrali-Noy, J Kühne, G Koch The Journal of general virology 1982 new
The isolation and characterization of DNA polymerase alpha from spinach. M Misumi, A Weissbach The Journal of biological chemistry 1982 new
Establishment of hybridoma clones which produce anti-chick embryo DNA polymerase alpha monoclonal antibodies. Akio Matsukage, Masamitsu Yamaguchi, K Tanabe, Masatoyo Nishizawa, Tomosaburo Takahashi, M Seto, Tetsuya Takahashi Gann 1982 new
Rapid hydrolysis of deoxynucleoside triphosphates accompanies DNA synthesis by T4 DNA polymerase and T4 accessory proteins 44/62 and 45. A C Roth, Nancy G Nossal, Paul T Englund The Journal of biological chemistry 1982 topics set
DNA polymerase beta involvement in DNA endoreduplication in rat giant trophoblast cells. R L Siegel, G F Kalf The Journal of biological chemistry 1982 new
Effect of an ecdysteroid on DNA synthesis, DNA polymerase a and thymidine kinase activities of Drosophila melanogaster cells in vitro. N Munsch, D Cade-Treyer Experientia 1982 new
Pyrophosphate analogues as inhibitors of DNA polymerases of cytomegalovirus, herpes simplex virus and cellular origin. B Eriksson, Bo Oberg, B Wahren Biochimica et biophysica acta 1982 new
De novo DNA synthesis by a novel mouse DNA polymerase associated with primase activity. T Kozu, T Yagura, T Seno Nature 1982 new
Regulation of DNA polymerase beta in rat adrenal gland by adrenocorticotropic hormone. Akio Nagasaka, Shonen Yoshida Endocrinology 1982 new
Antiviral effects of phosphonoformate (PFA, foscarnet sodium). Bo Oberg Pharmacol Ther 1982 new
Mouse DNA polymerase accompanied by a novel RNA polymerase activity: purification and partial characterization. T Yagura, T Kozu, T Seno J Biochem 1982 new
Evolution of DNA polymerase alpha, beta and terminal deoxynucleotidyl transferase in hamster lymphoid populations during the development of different types of tumors. N Munsch, C de Vaux Saint-Cyr, A Duthu, H Haddada, N Le Goffic, J Zuinghedau Biomed Pharmacother 1982 new
Effect of arabinosyl cytosine on the level of DNA polymerase and thymidine kinase activity in PHA-stimulated human tonsillar lymphocytes. M Staub, M Sasvári-Székely, T Spasokukockaja, F Antoni Mol Cell Biochem 1982 new
A DNA primase activity associated with DNA polymerase alpha from Drosophila melanogaster embryos. R C Conaway, I. Robert Lehman Proceedings of the National Academy of Sciences of the United States of America 1982 new
DNA polymerase alpha from the nuclear matrix of cells infected with simian virus 40. C Jones, R T Su Nucleic acids research 1982 new
Inhibition of the T7 DNA polymerase by insulin. H Randahl FEBS letters 1982 pols set
The relationship of hepatitis B e antigen, DNA polymerase activity, and titer of hepatitis B surface antigen with ongoing liver injury in chronic hepatitis B virus infection. R Perrillo, C Campbell, W Wellinghoff, L Gelb Am J Gastroenterol 1982 new
Adenovirus DNA replication in vitro: identification of a host factor that stimulates synthesis of the preterminal protein-dCMP complex. K Nagata, R A Guggenheimer, Takemi Enomoto, J H Lichy, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1982 new
Biosynthesis of DNA polymerase beta in chick embryonic cells. Masamitsu Yamaguchi, Akio Matsukage, T Takahashi, T Takahashi The Journal of biological chemistry 1982 new
ATP activation of DNA polymerase III holoenzyme of Escherichia coli. I. ATP-dependent formation of an initiation complex with a primed template. Peter M J Burgers, Arthur Kornberg The Journal of biological chemistry 1982 partial results
Viroid RNA is accepted as a template for in vitro transcription by DNA-dependent DNA polymerase I and RNA polymerase from Escherichia coli. W Rohde, H R Rackwitz, F Boege, H L Sänger Biosci Rep 1982 pols set
Polymerization/excision kinetics of Escherichia coli DNA polymerase I. Stability in kinetic behaviour and variations of the rate constants with temperature and pH. M Saghi, M Dorizzi Eur J Biochem 1982 pols set
Transition of DNA polymerase-alpha and endoplasmic reticulum during gastrulation of the sea urchin. M Shioda, H Nagano, Y Mano Dev Biol 1982 new
Effects of DNA polymerase inhibitors on replicative and repair DNA synthesis in ultraviolet-irradiated HeLa cells. T Morita, Yasuhiro Tsutsui, Yoshitaka Nishiyama, Hiroaki Nakamura, Shonen Yoshida Int J Radiat Biol Relat Stud Phys Chem Med 1982 new
Characterization of the action of Escherichia coli DNA polymerase I at incisions produced by repair endodeoxyribonucleases. D W Mosbaugh, Stuart Linn The Journal of biological chemistry 1982 pols set
The mutagenic effect of deoxynucleotide substrate imbalances during DNA synthesis with mammalian DNA polymerases. Thomas A Kunkel, J R Silber, Lawrence A Loeb Mutation research 1982 new
DNA polymerase and thymidine kinase activities in different regions of rat brain during postnatal development: effect of undernutrition. I Serra, A Vanella, R Avola, A M Giuffrida Neurochem Res 1982 new
Changes in DNA-polymerase and thymidine kinase activity during interferon treatment. D Lundblad, E Lundgren Biochem Biophys Res Commun 1982 new
Probable involvement of a glycoconjugate in IMR-32 DNA synthesis: decrease of DNA polymerase alpha 2 activity after tunicamycin treatment. P Bhattacharya, S Basu Proceedings of the National Academy of Sciences of the United States of America 1982 new
Preparation and preliminary characterization of monoclonal antibodies against human DNA polymerase alpha. Shigeru Tanaka, S Z Hu, Teresa S-F Wang, D Korn The Journal of biological chemistry 1982 pols set
Structural homology among calf thymus alpha-polymerase polypeptides. W Albert, F Grummt, Ulrich Hübscher, Samuel H Wilson Nucleic acids research 1982 new
Mutagenesis by alkylating agents: coding properties for DNA polymerase of poly (dC) template containing 3-methylcytosine. Serge Boiteux, Jacques Laval Biochimie 1982 pols set
Bacteriophage T4 gene 44/62 and gene 45 polymerase accessory proteins stimulate hydrolysis of duplex DNA by T4 DNA polymerase. M Venkatesan, Nancy G Nossal The Journal of biological chemistry 1982 complete
Induction of alkaline phosphatase and the glycoprotein hormone alpha subunit in HeLa cells by inhibitors of DNA polymerase. G S Cox, K H Park Arch Biochem Biophys 1982 new
Body growth and lymphocyte DNA polymerase activity in patients with hypopituitarism. H G Jasper, C Bergadá Medicina (B Aires) 1982 new
Purification and characterization of DNA polymerase III'. Identification of tau as a subunit of the DNA polymerase III holoenzyme. Charles S McHenry The Journal of biological chemistry 1982 partial results
Kinetic measurement of 2-aminopurine X cytosine and 2-aminopurine X thymine base pairs as a test of DNA polymerase fidelity mechanisms. S M Watanabe, Myron F Goodman Proceedings of the National Academy of Sciences of the United States of America 1982 new
Depurination of DNA as a possible mutagenic pathway for cells. Roel M Schaaper, Thomas A Kunkel, Lawrence A Loeb Basic life sciences 1982 new
DNA polymerase delta: one polypeptide, two activities. L P Goscin, J J Byrnes Biochemistry 1982 new
Mutations in the herpes simplex virus DNA polymerase gene can confer resistance to 9-beta-D-arabinofuranosyladenine. Donald M Coen, Phillip A Furman, P T Gelep, P A Schaffer Journal of virology 1982 new
The mechanism of inorganic phosphate-mediated inhibition of calf thymus DNA polymerase beta and Rauscher leukemia virus dna polymerase. Mukund J Modak, K Rao, S L Marcus Biochem Biophys Res Commun 1982 new
A new class of mutants in DNA polymerase I that affects gene transposition. M Syvanen, J D Hopkins, M Clements Journal of molecular biology 1982 new
Separation of the adenovirus terminal protein precursor from its associated DNA polymerase: role of both proteins in the initiation of adenovirus DNA replication. J H Lichy, J Field, M S Horwitz, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1982 new
Inhibition of calf thymus DNA polymerase alpha and of normal and cancer cell growth by butylanilinouracil and butylphenylguanine. M Rochowska, J Siedlecki, H Skurzak, G Wright, B Z Zmudzka Biochimica et biophysica acta 1982 new
Inhibition of DNA polymerase by captan. J W Dillwith, R A Lewis Biochimica et biophysica acta 1982 new
Design and characterization of N2-arylaminopurines which selectively inhibit replicative DNA synthesis and replication-specific DNA polymerases: guanine derivatives active on mammalian DNA polymerase alpha and bacterial DNA polymerase III. George E Wright, E F Baril, V M Brown, Neal C Brown Nucleic acids research 1982 new
An autoradiographic demonstration of nuclear DNA replication by DNA polymerase alpha and of mitochondrial DNA synthesis by DNA polymerase gamma. M Geuskens, N Hardt, G Pedrali-Noy, Silvio Spadari Nucleic acids research 1981 topics set
Enzyme involved in DNA replication in the axolotl. I. Analysis of the forms and activities of DNA polymerase and DNA ligase during development. D Carré, J Signoret, J Lefresne, J C David Dev Biol 1981 new
Synthesis of parvovirus H-1 replicative form from viral DNA by DNA polymerase gamma. R Kollek, Mehran Goulian Proceedings of the National Academy of Sciences of the United States of America 1981 new
Cooperation of terminal deoxynucleotidyl transferase with DNA polymerase alpha in the replication of ultraviolet-irradiated DNA. Shonen Yoshida, S Masaki, Hiroaki Nakamura, T Morita Biochimica et biophysica acta 1981 new
Size classes of products synthesized processively by DNA polymerase III and DNA polymerase III holoenzyme of Escherichia coli. P J Fay, K O Johanson, Charles S McHenry, Robert A Bambara The Journal of biological chemistry 1981 pols set
Enrichment of DNA polymerase III activity in a DNA membrane complex purified from Pneumococcus: the possible existence of subcomplexes. W Firshein, I W Gelman Mol Gen Genet 1981 new
Acyclovir-resistant mutants of herpes simplex virus type 1 express altered DNA polymerase or reduced acyclovir phosphorylating activities. Phillip A Furman, Donald M Coen, M H St Clair, P A Schaffer J Virol 1981 new
Synthesis by DNA polymerase I on bleomycin-treated deoxyribonucleic acid: a requirement for exonuclease III. O Niwa, Robb E Moses Biochemistry 1981 pols set
Aphidicolin does not inhibit DNA repair synthesis in ultraviolet-irradiated HeLa cells. A radioautographic study. N Hardt, G Pedrali-Noy, Federico Focher, Silvio Spadari The Biochemical journal 1981 topics set
A modified technique for the detection of hepatitis B virus-specific DNA polymerase. C T Fang, N Nath, M Pielech, R Y Dodd J Virol Methods 1981 new
Effect of ischemia on the activity of DNA-dependent RNA polymerase and DNA polymerase. M Gottlieb, M Chavko, J Marsala J Neurochem 1981 new
Further characterization of a poly(rA) . oligo(dT)-dependent activity of multiple DNA polymerase alpha from calf thymus. Shonen Yoshida, S Masaki, Osamu Koiwai Biochimica et biophysica acta 1981 new
Structural homology of DNA polymerase beta from various mammalian cells. K Tanabe, Masamitsu Yamaguchi, Akio Matsukage, Tomonori Takahashi The Journal of biological chemistry 1981 pols set
Preferential utilization of bromodeoxyuridine and iododeoxyuridine triphosphates by DNA polymerase gamma in vitro. S A Schwartz Biosci Rep 1981 new
Adenovirus DNA replication in vitro: purification of the terminal protein in a functional form. Takemi Enomoto, J H Lichy, J E Ikeda, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1981 new
On the molecular basis of transition mutations: frequencies of forming 2-aminopurine.cytosine and adenine.cytosine base mispairs in vitro. S M Watanabe, Myron F Goodman Proceedings of the National Academy of Sciences of the United States of America 1981 new
On the fidelity of DNA replication. Effect of the next nucleotide on proofreading. Thomas A Kunkel, Roel M Schaaper, R A Beckman, Lawrence A Loeb The Journal of biological chemistry 1981 pols set
Characterization of the DNA-dependent GTPase activity of T4 gene 41 protein, an essential component of the T4 bacteriophage DNA replication apparatus. Chin-Chi Liu, B M Alberts The Journal of biological chemistry 1981 complete
Characterization of the Epstein-Barr virion-associated DNA polymerase as isolated from superinfected and drug-stimulated cells. W Clough, J McMahon Biochimica et biophysica acta 1981 new
Stimulation of DNA polymerase beta activity in permeabilized mouse P815 mast cells after neocarzinostatin treatment. W Geurtsen, R K Zahn, A Maidhof, W E Müller Gann 1981 new
Herpes simplex virus type I DNA polymerase. Kinetic properties of the associated 3'-5' exonuclease activity and its role in araAMP incorporation. D Derse, Yung-Chi Cheng The Journal of biological chemistry 1981 new
Inhibition of DNA polymerase alpha by bleomycin. G FitzGerald, M M Wick Biochem Biophys Res Commun 1981 new
Nuclear DNA-polymerase estimation in human carcinomas. E Siim, G L Wantzin Biomedicine 1981 new
Replication of linear duplex DNA in vitro with bacteriophage T5 DNA polymerase. R K Fujimura, Somes K Das, D P Allison, B C Roop Prog Nucleic Acid Res Mol Biol 1981 pols set
The orderly, in vitro emergence of DNA from bacteriophage phi29 particles. S Krawiec, F Jiménez, J A García, N Villanueva, J Sogo, Margarita Salas Virology 1981 pols set
Structural organization of Bacillus subtilis phage phi29. A model. José L Carrascosa, E Méndez, J Corral, V Rubio, G Ramírez, Margarita Salas, E Viñuela Virology 1981 pols set
Polyamines stimulate natural RNA-directed DNA synthesis by Rauscher murine leukemia virus DNA polymerase. S L Marcus, S W Smith, C J Bacchi Biochem Biophys Res Commun 1981 new
Replication of adenovirus DNA-protein complex with purified proteins. J E Ikeda, Takemi Enomoto, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1981 new
Determination of nucleotide sequences in DNA. F Sanger Science 1981 new
Addition of deoxynucleotides to an RNA primer by a DNA polymerase in human platelets. D Gillespie, M Gaspari, D Strayer Biochem Biophys Res Commun 1981 new
On the activity and fidelity of chromatin-associated hepatic DNA polymerase-beta in aging murine species of different life spans. M Fry, Lawrence A Loeb, G M Martin J Cell Physiol 1981 new
HeLa cell DNA polymerase alpha is tightly associated with tryptophanyl-tRNA synthetase and diadenosine 5',5"'-P1,P4-tetraphosphate binding activities. E Rapaport, P C Zamecnik, E F Baril Proceedings of the National Academy of Sciences of the United States of America 1981 new
Structural and functional properties of calf thymus DNA polymerase delta. Marietta Y W T Lee, Cheng-Keat Tan, Kathleen M Downey, Antero G So Prog Nucleic Acid Res Mol Biol 1981 new
Studies on the inhibition of highly purified calf thymus 8S and 7.3S DNA polymerase alpha by aphidicolin. A M. Holmes Nucleic acids research 1981 new
Initiation of DNA replication at the primary origin of bacteriophage T7 by purified proteins: requirement for T7 RNA polymerase. Louis J Romano, F Tamanoi, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 1981 pols set
DNA polymerase activities in Friend cells during the differentiation process. R M Lacatena, V Busiello, A di Girolamo, M di Girolamo Cell Differ 1981 new
Knotted DNA from bacteriophage capsids. L F Liu, L Perkocha, R Calendar, J C Wang Proceedings of the National Academy of Sciences of the United States of America 1981 new
Influence of diverse gene 43 DNA polymerases on the incorporation and replication in vivo of 2-aminopurine at A X T base-pairs in bacteriophage T4. L S Ripley Journal of molecular biology 1981 complete
Poly (A) . oligo (dT)-stimulated DNA polymerase activity in preimplantation mouse embryos. A A Kiessling, H M Weitlauf J Exp Zool 1981 new
Role of DNA polymerase gamma in adenovirus DNA replication. Mechanism of inhibition by 2',3'-dideoxynucleoside 5'-triphosphates. Peter C van der Vliet, M M Kwant Biochemistry 1981 new
Changes in hepatitis B virus DNA-polymerase activity in patients with chronic infection. A Alberti, P Pontisso, G Realdi J Med Virol 1981 new
Physical mapping of drug resistance mutations defines an active center of the herpes simplex virus DNA polymerase enzyme. K W Knopf, E R Kaufman, C Crumpacker J Virol 1981 new
Accessory proteins for DNA polymerase alpha activity with single-strand DNA templates. P Lamothe, B Baril, A Chi, L Lee, E Baril Proceedings of the National Academy of Sciences of the United States of America 1981 new
A simple and efficient method for the isolation of DNA polymerase I from bacteria. U Wähnert FEBS letters 1981 new
Nonrandom substitution of 2-aminopurine for adenine during deoxyribonucleic acid synthesis in vitro. R C Pless, L M Levitt, M J Bessman Biochemistry 1981 complete
Ordered sequential mechanism of substrate recognition and binding by KB cell DNA polymerase alpha. Paul A Fisher, D Korn Biochemistry 1981 pols set
Effect of spermine on the activity of herpes simplex virus type 1 DNA polymerase: influence of the template. H M Wallace, H N Baybutt, C K Pearson, H M Keir FEBS letters 1981 new
[Inhibition of hepatitis B virus associated DNA polymerase by antiviral agents: in vitro studies with clinical implications (author's transl)]. G Hess, W Arnold, T H Hütteroth, K H Meyer zum Büschenfelde Z Gastroenterol 1981 new
Incorporation into DNA of the base analog 2-aminopurine by the Epstein-Barr virus-induced DNA polymerase in vivo and in vitro. D Grossberger, W Clough Proceedings of the National Academy of Sciences of the United States of America 1981 topics set
Human cytomegalovirus-associated DNA polymerase and protein kinase activities. E C Mar, P C Patel, E S Huang The Journal of general virology 1981 new
Yield of DNA strand breaks and their relationship to DNA polymerase I-dependent repair synthesis and ligation following X-ray exposure of toluene-treated Escherichia coli. D Billen Radiat Res 1981 new
Short deoxyribonucleic acid repair patch length in Escherichia coli is determined by the processive mechanism of deoxyribonucleic acid polymerase I. S W Matson, Robert A Bambara J Bacteriol 1981 partial results
On the fidelity of DNA replication. Nucleoside monophosphate generation during polymerization. Lawrence A Loeb, D K Dube, R A Beckman, M Koplitz, K P Gopinathan The Journal of biological chemistry 1981 new
The dnaN gene codes for the beta subunit of DNA polymerase III holoenzyme of escherichia coli. Peter M J Burgers, Arthur Kornberg, Y Sakakibara Proceedings of the National Academy of Sciences of the United States of America 1981 pols set
Suppressor cell activity in tumor-bearing mice. III. Co-purification of a factor inhibiting cellular DNA synthesis and DNA polymerase activity. W L Farrar, K D Elgert, A S Foo J Immunol 1981 new
Evidence for the absence of DNA proofreading in HeLa cell nuclei. M L Wang, R H Stellwagen, Myron F Goodman The Journal of biological chemistry 1981 new
Mechanism of dnaB protein action. IV. General priming of DNA replication by dnaB protein and primase compared with RNA polymerase. K Arai, Arthur Kornberg The Journal of biological chemistry 1981 pols set
Heterogeneous forms of poly(rA) . oligo(dT)-directed DNA polymerase activity from rat spleen. T Kozu, T Kurihara, T Seno J Biochem 1981 new
The effect of gamma-irradiated DNA on the activity of DNA polymerase. S A Leadon, J F Ward Radiat Res 1981 new
Properties of the primer-binding site and the role of magnesium ion in primer-template recognition by KB cell DNA polymerase alpha. Paul A Fisher, D Korn Biochemistry 1981 new
Identification of living spermatogenic cells of the mouse by transillumination-phase contrast microscopic technique for 'in situ' analyses of DNA polymerase activities. M Parvinen, N B Hecht Histochemistry 1981 new
Increased error frequency of DNA polymerases from senescent human fibroblasts. V Murray, R Holliday Journal of molecular biology 1981 new
Fidelity of mammalian DNA polymerases. Thomas A Kunkel, Lawrence A Loeb Science 1981 pols set
DNA polymerase, DNA ligase, and thymidine kinase activity in chicken lens, related to DNA X-ray lesion repair. M F Counis, J C David, E Chaudun, D Carre Differentiation 1981 new
Identification of a polypeptide component of mouse myeloma DNA polymerase gamma. Akio Matsukage, K Tanabe, Masamitsu Yamaguchi, Y N Taguchi, Masatoyo Nishizawa, Tetsuya Takahashi, Tetsuya Takahashi Biochimica et biophysica acta 1981 new
Studies on the biochemical basis of mutation VI. Selection and characterization of a new bacteriophage T4 mutator DNA polymerase. Linda J Reha-Krantz, M J Bessman Journal of molecular biology 1981 complete
New views of the biochemistry of eucaryotic DNA replication revealed by aphidicolin, an unusual inhibitor of DNA polymerase alpha. J A Huberman Cell 1981 new
Association of diadenosine 5',5"'-P1,P4-tetraphosphate binding protein with HeLa cell DNA polymerase alpha. E Rapaport, P C Zamecnik, E F Baril The Journal of biological chemistry 1981 new
Characterization of bacteriophage T7 DNA polymerase purified to homogeneity by antithioredoxin immunoadsorbent chromatography. B Nordström, H Randahl, I Slaby, A Holmgren The Journal of biological chemistry 1981 partial results
Template recognition sequence for RNA primer synthesis by gene 4 protein of bacteriophage T7. Stanley Tabor, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 1981 pols set
DNA replication of X-irradiated human lymphocytes. S S Agarwal, E J Katz, A Krishan, Lawrence A Loeb Cancer research 1981 new
DNA polymerase accuracy and spontaneous mutation rates: frequencies of purine.purine, purine.pyrimidine, and pyrimidine.pyrimidine mismatches during DNA replication. A R Fersht, J W Knill-Jones Proceedings of the National Academy of Sciences of the United States of America 1981 new
Absence of ultraviolet-inducible DNA polymerase I-like activity in Escherichia coli strains harbouring R plasmids. C Upton, R J Pinney J Gen Microbiol 1981 pols set
Two types of replication proteins increase the rate at which T4 DNA polymerase traverses the helical regions in a single-stranded DNA template. C C Huang, J E Hearst, B M Alberts The Journal of biological chemistry 1981 topics set
Herpes specific and alpha DNA polymerase in nuclear envelope of BHK infected cells. M Herzberg, V Bibor-Hardy, R Simard Biochem Biophys Res Commun 1981 new
[Lymphocyte DNA-polymerase activity in the blood of cattle normally and in chronic lympholeukemia]. N A Kovalevskiĭ, Iu M Azizov, A V Aleshchenko, A D Belov Izv Akad Nauk SSSR Biol 1981 new
A new procedure for the simultaneous large-scale purification of bacteriophage-T4-induced polynucleotide kinase, DNA ligase, RNA ligase and DNA polymerase. G M Dolganov, A V Chestukhin, M F Shemyakin Eur J Biochem 1981 new
Kinetic characteristics which distinguish two forms of calf thymus DNA polymerase alpha. J W Hockensmith, Robert A Bambara Biochemistry 1981 new
Properties of soluble DNA polymerase from sera of hepatitis B virus carriers. J C Mao, E R Otis, I K Mushahwar, L R Overby J Med Virol 1981 new
Purification of a 9S DNA polymerase alpha species from calf thymus. Frank Grosse, Gerhard Krauss Biochemistry 1981 new
[Isolation and characterization of DNA polymerase alpha, beta and gamma from the cells of the loach (Misgurnus fossilis)]. V S Mikhaĭlov, D B Guliamov Biokhimiia 1981 new
Regulation of the synthesis of the T4 DNA polymerase (gene 43). R C Miller, E T Young, R H Epstein, H M Krisch, T Mattson, A Bolle Virology 1981 pols set
Relevance of HBe/anti-HBe system and DNA polymerase activity in chronic hepatitis-B virus carriers on haemodialysis. A prospective study. G Marchesini, M Zoli, A Angiolini, G Feliciangeli, A Santoro, P Ferroni, A R Zanetti Nephron 1981 new
(E)-5-(2-bromovinyl)-2'-deoxyuridine-5'-triphosphate as a DNA polymerase substrate. J Sági, A Szabolcs, A Szemzö, L Otvös Nucleic acids research 1981 pols set
Enzymological characterization of KB cell DNA polymerase-alpha. Regulation of template binding by nucleic acid base composition. Paul A Fisher, J T Chen, D Korn The Journal of biological chemistry 1981 new
Stimulation of DNA polymerase alpha by a nuclear DNA/protein complex. H Balabanova, B R Fridlender, F A Anderer J Supramol Struct Cell Biochem 1981 new
On the mechanism of selective inhibition of herpesvirus replication by (E)-5-(2-bromovinyl)-2'-deoxyuridine. H S Allaudeen, J W Kozarich, J R Bertino, Erik De Clercq Proceedings of the National Academy of Sciences of the United States of America 1981 new
Evidence that a high molecular weight replicative DNA polymerase is conserved during evolution. Ulrich Hübscher, A Spanos, W Albert, F Grummt, G R Banks Proceedings of the National Academy of Sciences of the United States of America 1981 pols set
DNA polymerase of a basidiomycete fungus, Coprinus cinereus. D Lowe, D Lewis Biochem J 1981 topics set
Elongation of RNA-primed DNA templates by DNA polymerase alpha from Drosophila melanogaster embryos. Giuseppe Villani, P J Fay, Robert A Bambara, I. Robert Lehman The Journal of biological chemistry 1981 new
Studies on the mechanism of DNA polymerase alpha. Nascent chain elongation, steady state kinetics, and the initiation phase of DNA synthesis. S D Detera, S P Becerra, J A Swack, Samuel H Wilson The Journal of biological chemistry 1981 new
Template-specific inhibitor for DNA polymerase isolated from cauliflower inflorescence. M Y Chou, H Matsumoto, H Fukata, H Fukasawa Biochimica et biophysica acta 1981 new
A protein stimulatory factor for DNA polymerase alpha in rat giant trophoblast cells. G F Kalf, R M Metrione, T R Koszalka Biochem Biophys Res Commun 1981 new
Deoxynucleoside [1-thio]triphosphates prevent proofreading during in vitro DNA synthesis. Thomas A Kunkel, F Eckstein, A S Mildvan, R M Koplitz, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1981 new
Differential effect of N-carboxymethylisatoylation on the DNA polymerase activity, the 5' leads to 3'-exonuclease activity and the 3' leads to 5'-exonuclease activity of DNA polymerase I of Escherichia coli. H Klenow, K Overgaard-Hansen Biochimica et biophysica acta 1981 pols set
Restoration of defective cellular functions by supply of DNA polymerase I to permeable cells of Escherichia coli. Kikuo Shimizu, K Yamashita, M Sekiguchi Biochem Biophys Res Commun 1981 pols set
A system of DNA replication in HeLa nuclei treated with inhibitors of protein synthesis. K Nagata, Takemi Enomoto, M A Yamada Biochimica et biophysica acta 1981 new
Variation of DNA polymerase activities of rat giant trophoblast cells in mid-gestation. G F Kalf, R M Metrione, B L Kerlavage, T R Koszalka Dev Biol 1981 new
The artifactual nature of fluoride inhibition of reverse transcriptase and associated ribonuclease H. S K Srivastava, E Gillerman, Mukund J Modak Biochemical and biophysical research communications 1981 new
Unambiguous determination of the stereochemistry of nucleotidyl transfer catalyzed by DNA polymerase I from Escherichia coli. R S Brody, P A Frey Biochemistry 1981 pols set
A mutant thioredoxin from Escherichia coli tsnC 7007 that is nonfunctional as subunit of phage T7 DNA polymerase. A Holmgren, G B Kallis, B Nordström The Journal of biological chemistry 1981 pols set
Duplex DNA binding activity of the avian myeloblastosis virus DNA polymerase. S W Matson, Robert A Bambara Biochimica et biophysica acta 1981 new
The effect of ATP on the incorporation of deoxyribonucleoside triphosphates by Escherichia coli DNA polymerase I. T Spasokukotskaja, M Staub, M Sasvári-Székely, F Antoni Biochimica et biophysica acta 1981 pols set
In vitro activation of DNA polymerase-alpha by a protein kinase in chick embryo. J M Danse, J M Egly, J Kempf FEBS letters 1981 new
The requirement for both DNA polymerase and 5' to 3' exonuclease activities of DNA polymerase I during Tn5 transposition. C Sasakawa, Y Uno, M Yoshikawa Mol Gen Genet 1981 new
E. coli DNA polymerase I: enzymatic functions and their application in polymer formation, nick translation and DNA sequencing. C P Hartman, D Rabussay Gene Amplif Anal 1981 pols set
Inhibition cyclic guanosine 3':5'-monophosphate of the soluble DNA polymerase activity, and of partially purified DNA polymerase A (DNA polymerase I) from the yeast Saccharomyces cerevisiae. H Eckstein Z Naturforsch C 1981 new
Purification and properties of DNA polymerase from Mycobacterium tuberculosis H37Rv. K T Hiriyanna, T Ramakrishnan Biochimica et biophysica acta 1981 pols set
Functional roles of the plant alpha-like and gamma-like DNA polymerases. F Sala, M G Galli, M Levi, D Burroni, B Parisi, G Pedrali-Noy, Silvio Spadari FEBS letters 1981 topics set
Differential inhibition of multiple forms of DNA polymerase alpha from IMR-32 human neuroblastoma cells. P Bhattacharya, I Simet, S Basu Proceedings of the National Academy of Sciences of the United States of America 1981 new
Induction of DNA polymerase in Tetrahymena pyriformis. J Keiding, H A Andersen Biochem Biophys Res Commun 1981 new
Aphidicolin inhibits DNA synthesis by DNA polymerase alpha and isolated nuclei by a similar mechanism. H Krokan, E Wist, R H Krokan Nucleic acids research 1981 new
Baculovirus induction of a DNA polymerase. L K Miller, J E Jewell, D Browne J Virol 1981 new
Alternate pathways of DNA replication: DNA polymerase I-dependent replication. O Niwa, S K Bryan, Robb E Moses Proceedings of the National Academy of Sciences of the United States of America 1981 pols set
[Isolation and properties of DNA-polymerase from the extreme thermophilic bacterium Thermus flavus]. A S Kaledin, A G Sliusarenko, S I Gorodetskiĭ Biokhimiia 1981 new
Divalent cation-dependent pyridoxal 5'-phosphate inhibition of Rauscher leukemia virus DNA polymerase: characterization and mechanism of action. Mukund J Modak, U J Dumaswala Biochimica et biophysica acta 1981 new
DNA-polymerase induced by Herpesvirus papio (HVP) in cells of lymphoblastoid cultures derived from lymphomatous baboons. Report V. A G Djachenko, B A Lapin Exp Pathol 1981 new
DNA polymerase activities during induced differentiation in murine erythroleukemia cells. J G Giri, R C Reuben, R A Rifkind, P A Marks Exp Cell Res 1981 new
[2 DNA synthesis enzyme systems in the nuclei of the loach Misgurnus fossilis. Participation of DNA polymerase alpha in the replication of embryonal nuclear DNA and DNA polymerase beta in the synthesis of hepatic nuclear DNA]. V S Mikhaĭlov, D B Guliamov Dokl Akad Nauk SSSR 1981 new
Mechanism of ultraviolet-induced mutagenesis: the coding properties of ultraviolet-irradiated poly(dC) replicated by E. coli DNA polymerase I. P Lecomte, Serge Boiteux, O Doubleday Nucleic acids research 1981 pols set
Depurination causes mutations in SOS-induced cells. Roel M Schaaper, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1981 new
Inhibition of hepatitis B virus specific DNA polymerase by intercalating agents. G Hess, W Arnold, B Möller, G M Gahl, K H Meyer zum Büschenfelde Med Microbiol Immunol 1980 new
Thermal sensitivity of eukaryotic DNA polymerase-alpha and protection by its templates. M Mechali, A M de Recondo FEBS letters 1980 new
Chromatographic resolution of two DNA polymerase activities from bloodstream forms of Trypanosoma brucei: differential responses to exogenous polyamine addition. S L Marcus, G Lipschik, G Trueba, C J Bacchi Biochem Biophys Res Commun 1980 new
Increase of DNA polymerase activities in HeLa Cells treated with N-methyl-N'-nitro-N-nitrosoguanidine. K Suzuki, M Miyaki, N Akamatsu, T Ono FEBS letters 1980 new
DNA binding proteins from calf thymus with an enhanced ability to stimulate DNA polymerase alpha in vitro. S Riva, A Clivio, O Valentini, F Cobianchi Biochem Biophys Res Commun 1980 new
3'-end labeling of DNA with [alpha-32P]cordycepin-5'-triphosphate. C P Tu, S N Cohen Gene 1980 partial results
Purification and characterization of the beta subunit of the DNA polymerase III holoenzyme of Escherichia coli. K O Johanson, Charles S McHenry The Journal of biological chemistry 1980 pols set
On the fidelity of deoxyribonucleic acid synthesis directed by chromatin-associated deoxyribonucleic acid polymerase beta. M Fry, C W Shearman, G M Martin, Lawrence A Loeb Biochemistry 1980 pols set
Pauses at positions of secondary structure during in vitro replication of single-stranded fd bacteriophage DNA by T4 DNA polymerase. C C Huang, J E Hearst Anal Biochem 1980 pols set
DNA polymerase gamma, cytochrome c oxidase and mitochondrial integrity in rabbit spleen lymphocytes stimulated with concanavalin A. N Hardt, D De Kegel, L Vanheule, Giuseppe Villani, Silvio Spadari Exp Cell Res 1980 new
[Effect of an inhibitor of replicative DNA-polymerase on the radioresistance of mice]. L N Belovskaia, I V Filippovich, V V Znamenskii, A V Terekhov, P G Zherebchenko Dokl Akad Nauk SSSR 1980 new
[DNA polymerase in the microsomal fraction of the myeloblasts of chickens infected with avian myeloblastosis virus]. W Bartnikowa Acta Haematol Pol 1980 new
Determination of mutation rates in bacteriophage T4 by unneighborly base pairs: genetic analysis. M A Conkling, R E Koch, John W Drake Journal of molecular biology 1980 topics set
DNA polymerase isolated from the mitochondrial chromosome appears to be identical to DNA polymerase-gamma. W J Adams, G F Kalf Biochem Biophys Res Commun 1980 new
Specific and reversible inhibition by aphidicolin in the alpha-like DNA polymerase of plant cells. F Sala, B Parisi, D Burroni, A R Amileni, G Pedrali-Noy, Silvio Spadari FEBS letters 1980 topics set
Purification and partial characterization of a DNA polymerase alpha species from calf thymus. Frank Grosse, Gerhard Krauss Nucleic acids research 1980 new
[DNA-dependent DNA polymerase induced by herpes virus papio (HVP) in producing cells]. A G D'iachenko, L Ia Beriia, L D Matsenko, V V Kakubava, L V Kokosh Biokhimiia 1980 new
Inhibitor studies on phage T4 wild-type and mutant DNA polymerase. IV. The substrate analog 3'-fluorothymidine 5'-triphosphate. C Schroeder, J Jantschak Z Allg Mikrobiol 1980 topics set
Properties of herpes simplex virus type 1 and type 2 DNA polymerase. M Ostrander, Yung-Chi Cheng Biochimica et biophysica acta 1980 new
The role of deoxyuridine triphosphate nucleotidohydrolase, uracil-DNA glycosylase, and DNA polymerase alpha in the metabolism of FUdR in human tumor cells. S J Caradonna, Yung-Chi Cheng Mol Pharmacol 1980 new
Pentaribonucleotides of mixed sequence are synthesized and efficiently prime de novo DNA chain starts in the T4 bacteriophage DNA replication system. Chin-Chi Liu, B M Alberts Proceedings of the National Academy of Sciences of the United States of America 1980 complete
Effects of estrogen and antiestrogen on DNA polymerase in human breast cancer. D P Edwards, S R Murthy, W L McGuire Cancer research 1980 new
[Isolation and properties of DNA polymerase from extreme thermophylic bacteria Thermus aquaticus YT-1] A S Kaledin, A G Sliusarenko, S I Gorodetskiĭ Biokhimii͡a (Moscow, Russia) 1980 topics set
DNA polymerase activity in aged clones of Paramecium tetraurelia. T J Williams, J Smith-Sonneborn Exp Gerontol 1980 new
DNA polymerase III-dependent repair synthesis in response to bleomycin in toluene-treated Escherichia coli. S L Ross, S Sharma, Robb E Moses Mol Gen Genet 1980 new
Inhibition of herpes simplex virus-induced DNA polymerase, cellular DNA polymerase alpha, and virus production by aphidicolin. R A Dicioccio, K Chadha, B I Sahai Srivastava Biochimica et biophysica acta 1980 new
The effect of cyclic nucleotides on DNA polymerase, thymidylate synthetase, thymidine kinase and deoxynucleoside levels of Waler carcinoma. M J Tisdale Chem Biol Interact 1980 new
Mechanism of inhibition of deoxyribonucleic acid synthesis by 1-beta-D-arabinofuranosyladenosine triphosphate and its potentiation by 6-mercaptopurine ribonucleoside 5'-monophosphate. Marietta Y W T Lee, J J Byrnes, Kathleen M Downey, Antero G So Biochemistry 1980 new
Chick embryo DNA polymerase gamma. Purification and structural analysis of nearly homogeneous enzyme. Masamitsu Yamaguchi, Akio Matsukage, Tomonori Takahashi The Journal of biological chemistry 1980 new
Ehrlich ascites cell (EAC) chalone assay using purified calf thymus-DNA polymerase alpha. G S Nakai, H Gergely Biomedicine 1980 new
Quantitative structure--activity correlations of rifamycins as inhibitors of viral RNA-directed DNA polymerase and mammalian alpha and beta DNA polymerases. R S Wu, M K Wolpert-DeFilippes, F R Quinn J Med Chem 1980 new
Mitochondrial DNA replication does not involve DNA polymerase alpha. W Zimmermann, S M Chen, A Bolden, A Weissbach The Journal of biological chemistry 1980 new
DNA polymerase activity, probably DNA polymerase alpha, remains associated to microtubules after successive polymerization cycles. J Avila Biochem Biophys Res Commun 1980 new
EMT6 solid tumor growth, DNA synthesis and DNA polymerase activity. Y Maruyama, M S Coleman, C Nava Cancer Biochem Biophys 1980 new
The dnaZ protein, the gamma subunit of DNA polymerase III holoenzyme of Escherichia coli. Ulrich Hübscher, Arthur Kornberg The Journal of biological chemistry 1980 pols set
Continuous synthesis of long DNA chains by chick embryo DNA polymerase gamma. Masamitsu Yamaguchi, Akio Matsukage, Tomonori Takahashi Nature 1980 new
On the fidelity of DNA replication. The accuracy of Escherichia coli DNA polymerase I in copying natural DNA in vitro. Thomas A Kunkel, Lawrence A Loeb The Journal of biological chemistry 1980 pols set
The DNA polymerase beta reaction with ultraviolet-irradiated DNA incised by correndonuclease. Radosława Nowak, Z Zarebska, B Z Zmudzka Biochimica et biophysica acta 1980 new
DNA polymerase alpha from Drosophila melanogaster embryos. Subunit structure. Giuseppe Villani, B Sauer, I. Robert Lehman The Journal of biological chemistry 1980 pols set
Chick embryo DNA polymerase beta. Purified enzyme consists of a single Mr = 40,000 polypeptide. Masamitsu Yamaguchi, K Tanabe, Y N Taguchi, Masatoyo Nishizawa, Tomonori Takahashi, Akio Matsukage The Journal of biological chemistry 1980 new
[Effect of exogenous RNA on the activity of poly(A).oligo(dT)-dependent DNA-polymerase in mouse tumors]. V P Tomsons, K N Verevkina, G B Pyrinova, R I Salganik Biokhimiia 1980 new
Replication of simian virus 40 chromatin in vitro depends on the amount of DNA polymerase alpha associated with replicating chromatin. A Richter, R Scheu, B Otto Eur J Biochem 1980 new
Characterization of two DNA polymerases from cauliflower inflorescence. H Fukasawa, Masamitsu Yamaguchi, M Y Chou, H Matsumoto, Akio Matsukage Journal of biochemistry 1980 new
Specific labeling of 3' termini with T4 DNA polymerase. M D Challberg, Paul T Englund Methods in enzymology 1980 pols set
Restriction fragment primed phi X174 single-stranded DNA as template for DNA polymerase alpha and beta. Detection and partial purification of a polymerase alpha stimulating factor. J F Burke, J Plummer, A J Huberman, M J Evans Biochimica et biophysica acta 1980 new
In vitro synthesis of short DNA pieces by DNA polymerase alpha from mouse myeloma. Akio Matsukage, Masatoyo Nishizawa, Tomonori Takahashi, T Hozumi J Biochem 1980 new
DNA-dependent RNA polymerase in African swine fever virus. J Kuznar, María L Salas, E Viñuela Virology 1980 pols set
Mechanism of primer-template-dependent conversion of dNTP leads to dNMP by T5 DNA polymerase. Somes K Das, R K Fujimura The Journal of biological chemistry 1980 new
Evidence implying DNA polymerase beta function in excision repair. Janusz A Siedlecki, J Szyszko, I Pietrzykowska, B Z Zmudzka Nucleic acids research 1980 new
DNA polymerase alpha mutants from a Drosophila melanogaster cell line. Akio Sugino, K Nakayama Proceedings of the National Academy of Sciences of the United States of America 1980 new
Initiation of DNA replication by the dnaG protein. E W Benz, D Reinberg, R Vicuna, Jerard Hurwitz The Journal of biological chemistry 1980 new
Elongation of primed DNA templates by eukaryotic DNA polymerases. J E Ikeda, M Longiaru, M S Horwitz, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1980 new
Steady-state kinetics of mouse DNA polymerase alpha. K Tanabe, Y N Taguchi, Akio Matsukage, Tomonori Takahashi J Biochem 1980 new
DNA polymerase I and recBC enzyme support the covalent closing of hydrogen-bonded lambda DNA circles in extracts of Escherichia coli cells. M J Pyhtilä, Juhani E Syväoja Eur J Biochem 1980 new
Trisodium phosphonoformate inhibits woodchuck hepatitis virus associated DNA polymerase. E Nordenfelt, B Werner Acta Pathol Microbiol Scand B 1980 new
Immunoelectron microscopic observation of hepatitis B surface antigen on the surface of liver cells from patients with hepatitis B virus infection. G Yamada, Tomonori Takahashi, M Mizuno, Y Sakamoto, K Kaga, T Kobayashi, H Nagashima Acta medica Okayama 1980 pols set
Phenylglyoxal as a template site-specific reagent for DNA and RNA polymerases. Selective inhibition of initiation. Aashish Srivastava, Mukund J Modak The Journal of biological chemistry 1980 new
Mechanism of inhibition of herpes simplex virus and vaccinia virus DNA polymerases by aphidicolin, a highly specific inhibitor of DNA replication in eucaryotes. G Pedrali-Noy, Silvio Spadari Journal of virology 1980 topics set
Properties of a DNA polymerase from purified nuclei and DNA-synthesizing complexes of human spermatozoa. S S Witkin J Reprod Fertil 1980 new
Intracellular localization of DNA polymerase activities within large oocytes of the frog, Xenopus laevis. A M Fox, C B Breaux, R M Benbow Dev Biol 1980 new
Inhibition of calf thymus DNA polymerase-alpha by deoxyribonucleoside triphosphates. G B Grindey, M Winkler, M Otten, J A Steinberg Mol Pharmacol 1980 new
Enzymatic activities associated with avian and murine retroviral DNA polymerases. Catalysis of and active site involvement in pyrophosphate exchange and pyrophosphorolysis reactions. Aashish Srivastava, Mukund J Modak The Journal of biological chemistry 1980 new
[Surface antigen (HBsAg) and core antibody (anti-HBc) in chronic uremia during periodic hemodialysis treatment of hepatitis B patients. Correlation with viral replication markers (HBeAg and DNA polymerase activity)]. R Buongiorno, P Dentico, T Santantonio, V Frappampina, A Spinelli, M Amato, G Pastore Boll Soc Ital Biol Sper 1980 new
Persistent cytoplasmic location of a DNA polymerase beta in sea urchins during development. P M Hobart, A A Infante Biochimica et biophysica acta 1980 new
Decreased fidelity in one subspecies of DNA polymerase-alpha that appears during N-2-acetylaminofluorene hepatocarcinogenesis. J Y Chan, F F Becker Biochimica et biophysica acta 1980 new
Quantitative relationship between HBeAg and DNA polymerase activity in sera from patients with chronic active hepatitis during a three-month period. R A Heijtink, M van der Waart, W Weimar, S W Schalm, N Masurel J Med Virol 1980 new
Induction of Epstein-Barr virus-associated DNA polymerase by 12-O-tetradecanoylphorbol-13-acetate. Purification and characterization. A K Datta, R J Feighny, Joseph S Pagano The Journal of biological chemistry 1980 new
Association of DNA polymerase alpha and beta with rough endoplasmic reticulum in sea-urchin eggs and changes in subcellular distribution during early embryogenesis. M Shioda, H Nagano, Y Mano Eur J Biochem 1980 new
[Isolation of RNA polymerase and DNA polymerase from Streptomyces strains]. J Bieber, R Nüske, U Wähnert, B Hartung Z Allg Mikrobiol 1980 new
Inhibitors of Bacillus subtilis DNA polymerase III. 6-Anilinouracils and 6-(alkylamino)uracils. George E Wright, Neal C Brown J Med Chem 1980 new
A gamma-like DNA polymerase in spinach chloroplasts. F Sala, A R Amileni, B Parisi, Silvio Spadari European journal of biochemistry / FEBS 1980 topics set
Induction of DNA polymerase activity after superinfection of Raji cells with Epstein-Barr virus. R J Feighny, B E Henry, A K Datta, Joseph S Pagano Virology 1980 new
Age-dependent alterations of DNA synthesis. Terminal deoxynucleotidyl transferase and DNA polymerase activities in bone marrow subpopulations from mice. W E Müller, R K Zahn, W Geurtsen, N Munsch Mech Ageing Dev 1980 new
In vitro DNA replication of recombinant plasmid DNAs containing the origin of progeny replicative form DNA synthesis of phage phi X174. S L Zipursky, D Reinberg, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1980 new
Butylanilinouracil: a selective inhibitor of HeLa cell DNA synthesis and HeLa cell DNA polymerase alpha. George E Wright, E F Baril, Neal C Brown Nucleic acids research 1980 topics set
A beta-like DNA polymerase activity in the slime mold Dictyostelium discoideum. E F Baril, C Scheiner, T Pederson Proceedings of the National Academy of Sciences of the United States of America 1980 topics set
Inhibition of hepatitis B Dane particle DNA polymerase activity by pyrophosphate analogs. E Nordenfelt, Bo Oberg, E Helgstrand, E Miller Acta Pathol Microbiol Scand B 1980 new
[Inhibition of the 3' to 5' exonuclease activity of the DNA polymerase I of Escherichia coli by deoxyribonucleotides]. M Granger, F Toulmé, C Hélène C R Seances Acad Sci D 1980 pols set
Molecular basis for substitution mutations. Effect of primer terminal and template residues on nucleotide selection by phage T4 DNA polymerase in vitro. M D Topal, S R DiGuiseppi, N K Sinha The Journal of biological chemistry 1980 complete
Isolation and characterization of a mutant of Escherichia coli K12 synthesizing DNA polymerase I and endonuclease I constitutively. S I Ahmad, A Atkinson, A Eisenstark J Gen Microbiol 1980 new
Effects of arsenic, selenium, and chromium on the fidelity of DNA synthesis. L K Tkeshelashvili, C W Shearman, R A Zakour, R M Koplitz, Lawrence A Loeb Cancer research 1980 pols set
Inhibition of hepatitis-B-virus DNA polymerase by phosphonoformate: studies on its mode of action. G Hess, W Arnold, K H Meyer zum Büschenfelde J Med Virol 1980 new
Determination of serum DNA polymerase activities in hepatitis B carriers. Chin Med J (Engl) 1980 new
Mechanism of 3' to 5' exonuclease associated with phage T5-induced DNA polymerase: processiveness and template specificity. Somes K Das, R K Fujimura Nucleic acids research 1980 new
Catalysis of adenovirus DNA synthesis in vitro by DNA polymerase gamma. C H Shaw, D M Rekosh, W C Russell The Journal of general virology 1980 new
Purification of deoxyribonucleic acid polymerase delta from calf thymus: partial characterization of physical properties. Marietta Y W T Lee, Cheng-Keat Tan, Antero G So, Kathleen M Downey Biochemistry 1980 new
Synchronization of HeLa cell cultures by inhibition of DNA polymerase alpha with aphidicolin. G Pedrali-Noy, Silvio Spadari, A Miller-Faurès, A O Miller, J Kruppa, G Koch Nucleic acids research 1980 topics set
The effect of polyamines on herpes simplex virus type 1 DNA polymerase purified from infected baby hamster kidney cells (BHK-21/C13). H M Wallace, H N Baybutt, C K Pearson, H M Keir The Journal of general virology 1980 new
Long-term follow-up of chronic hepatitis patients with HBsAg, HBeAg and Dane particles associated DNA polymerase in serum. G Norkrans, E Nordenfelt, S Hermodsson, S Iwarson Scand J Infect Dis 1980 new
DNA polymerase alpha is tightly bound to the nuclear matrix of actively replicating liver. H C Smith, R Berezney Biochem Biophys Res Commun 1980 new
RNA priming of DNA replication by bacteriophage T4 proteins. Nancy G Nossal The Journal of biological chemistry 1980 complete
[DNA-polymerase from sea urchin (Strongylocentrotus intermedius. Embryos]. L L Terent'ev, N A Terent'eva, V A Rassazov Biokhimiia 1980 new
Fidelity of DNA replication catalysed in vitro on a natural DNA template by the T4 bacteriophage multi-enzyme complex. U Hibner, B M Alberts Nature 1980 complete
Efficient in vitro replication of double-stranded DNA templates by a purified T4 bacteriophage replication system. N K Sinha, C F Morris, B M Alberts The Journal of biological chemistry 1980 partial results
[Aphidicolin: a specific inhibitor of eukaryotic DNA polymerase alpha (author's transl)]. H Nagano, S Ikegami Seikagaku 1980 new
DNA synthesis in isolated chromatin. Nature of activities, and relationship to kinetics of DNA polymerase release from chromatin DNA. T Yagura, T Seno Biochimica et biophysica acta 1980 new
Inhibition of Escherichia coli DNA polymerase I by rose bengal. A M Stern, V D'Aurora, D S Sigman Arch Biochem Biophys 1980 pols set
Partial purification and characterization of poly(dC)-dependent DNA polymerase and its stimulating factor. T Yagura, T Kozu, T Seno Biochem Biophys Res Commun 1980 new
Characterization of a DNA polymerase activity in cultured human melanoma cells that copies poly(2'-O-methylcytidylate). G F Gerard, P M Loewenstein, M Green The Journal of biological chemistry 1980 new
X-ray induced activity of N-ethylmaleimide-sensitive DNA polymerase in Chinese hamster cells. R G Ramsay, M Westerman Aust J Biol Sci 1980 new
[Affinity modification of Escherichia coli Dna-polymerase I by 4-(N-2-chloroethyl-N-methylamino)-benzyl-gamma-amides of dTTP and dATP]. V N Buneva, T V Demidova, D G Knorre, N V Kudriashova, A G Romashchenko Mol Biol (Mosk) 1980 new
Two distinct loci confer resistance to acycloguanosine in herpes simplex virus type 1. Donald M Coen, P A Schaffer Proceedings of the National Academy of Sciences of the United States of America 1980 new
[Markers of viral replication (HBeAg and DNA polymerase activity) in chronic uremia, HBsAg positive, hemodialysis patients]. P Dentico, R Buongiorno, G Angarano, L Monno, S Coppola, V Laddago, A Spinelli, G Pastore Boll Soc Ital Biol Sper 1980 new
Pyrophosphate analogues as inhibitors of herpes simplex virus type 1 DNA polymerase. B Eriksson, A Larsson, E Helgstrand, N G Johansson, Bo Oberg Biochimica et biophysica acta 1980 new
Purification from Tetrahymena thermophila of DNA polymerase and a protein which modifies its activity. P R Ganz, R E Pearlman Eur J Biochem 1980 new
Eukaryotic DNA polymerase alpha. Structural analysis of the enzyme from regenerating rat liver. M Mechali, J Abadiedebat, A M de Recondo The Journal of biological chemistry 1980 new
Levodopa and dopamine analogs as DNA polymerase inhibitors and antitumor agents in human melanoma. M M Wick Cancer research 1980 new
Oxygen-dependent cleavage of DNA by the 1,10-phenanthroline . cuprous complex. Inhibition of Escherichia coli DNA polymerase I. D S Sigman, D R Graham, V D'Aurora, A M Stern The Journal of biological chemistry 1979 pols set
Enzymological characterization of KB cell DNA polymerase-alpha. II. Specificity of the protein-nucleic acid interaction. Paul A Fisher, D Korn The Journal of biological chemistry 1979 new
Quantitative assay of hepatitis B surface antigen and DNA polymerase activity. R A Heijtink, S W Schalm N Engl J Med 1979 new
Studies on the processivity of highly purified calf thymus 8S and 7.3S DNA polymerase alpha. K McKune, A M. Holmes Biochem Biophys Res Commun 1979 new
A high molecular weight DNA polymerase from Drosophila melanogaster embryos. Purification, structure, and partial characterization. G R Banks, J A Boezi, I. Robert Lehman The Journal of biological chemistry 1979 new
Cell proliferation and DNA dependent DNA polymerase estimation in acute lymphoblastic leukaemia during treatment with prednisone and vincristine. G Lange Wantzin Scand J Haematol 1979 new
Regulation of DNA synthesis and DNA polymerase in rat pancreas. II. Age-dependent changes in glucocorticoid control. Yu Sam Kim, I Jatoi, Y Kim Exp Mol Pathol 1979 new
DNA polymerase III of Escherichia coli. Purification and identification of subunits. Charles S McHenry, W Crow The Journal of biological chemistry 1979 pols set
[Unprimed synthesis of poly (d(A-T)), catalyzed by a preparation of Escherichia coli DNA polymerase I]. I A Nazarenko, L E Bobko, A G Romashchenko, Iu L Khripin, R I Salganik Mol Biol (Mosk) 1979 pols set
Suramin: a potent inhibitor of the reverse transcriptase of RNA tumor viruses. Erik De Clercq Cancer letters 1979 new
Selective inhibition of the polymerase activity of DNA polymerase. I. Further evidence for separate active sites for polymerase and 3' to 5' exonuclease activities. B G Que, Kathleen M Downey, Antero G So Biochemistry 1979 new
"Nick translation" in Escherichia coli rep strains deficient in DNA polymerase I activities. C Hours, D T Denhardt Mol Gen Genet 1979 new
Initiation of replication of plasmid ColE1 DNA by RNA polymerase, ribonuclease H, and DNA polymerase I. T Itoh, J Tomizawa Cold Spring Harbor symposia on quantitative biology 1979 new
Induction of host DNA synthesis and DNA polymerase by DNA-negative temperature-sensitive mutants of human cytomegalovirus. K Yamanishi, F Rapp Virology 1979 pols set
Pyrimidine dimer excision in Escherichia coli strains deficient in exonucleases V and VII and in the 5' leads to 3' exonuclease of DNA polymerase I. J W Chase, W E Masker, J B Murphy J Bacteriol 1979 new
Single-strand binding protein enhances fidelity of DNA synthesis in vitro. Thomas A Kunkel, R R Meyer, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1979 new
DNA endonucleases associated with the avian myeloblastosis virus DNA polymerase. K P Samuel, T S Papas, J G Chirikjian Proceedings of the National Academy of Sciences of the United States of America 1979 new
Unique requirements for template primers of DNA polymerase beta from rat ascites hepatoma AH130 cells. K Ono, A Ohashi, K Tanabe, Akio Matsukage, Masatoyo Nishizawa, Tomonori Takahashi Nucleic acids research 1979 new
Mutagenesis in vitro by DNA polymerase from an RNA tumour virus. K P Gopinathan, L A Weymouth, Thomas A Kunkel, Lawrence A Loeb Nature 1979 new
[Use of the DNA-polymerase reaction for studying hepatitis type B]. N A Ogareva, S O Viazov, M I Mikhaĭlov, G K Zairov, E A Paktoris Vopr Virusol 1979 new
Effects of depurination on the fidelity of DNA synthesis. C W Shearman, Lawrence A Loeb Journal of molecular biology 1979 new
Enhancement of the rate of DNA polymerase-alpha activity on duplex DNA by a DNA-binding protein and a DNA-dependent ATPase of mammalian cells. F Cobianchi, S Riva, G Mastromei, Silvio Spadari, G Pedrali-Noy, A Falaschi Cold Spring Harbor symposia on quantitative biology 1979 new
DNA replication by bacteriophage T4 proteins: role of the DNA-delay gene 61 in the chain-initiation reaction. Lynn L Silver, Nancy G Nossal Cold Spring Harbor symposia on quantitative biology 1979 complete
Steady-state kinetics of mouse DNA polymerase beta. K Tanabe, E W Bohn, Samuel H Wilson Biochemistry 1979 new
Characterization of an Epstein-Barr virus-induced DNA polymerase. T Ooka, G Lenoir, J Daillie J Virol 1979 partial results
Decreased production of transforming virus and altered antigenic behaviour in cultured avian sarcoma cells. Mark A. Wainberg, M Yu, E Israel The Journal of general virology 1979 new
A study of the mechanism of DNA polymerase I from Escherichia coli with diastereomeric phosphorothioate analogs of deoxyadenosine triphosphate. Peter M J Burgers, F Eckstein The Journal of biological chemistry 1979 pols set
[Molecular mechanism of action of diamidinephenylindole (DAPI). II. Effect of DAPI on the template activity of DNA and polydeoxynucleotides in the DNA-polymerase system from bacteria, eukaryotic cells and RNA tumor viruses (author's transl)]. B Mildner, P Chandra Cell Mol Biol Incl Cyto Enzymol 1979 new
DNA polymerase activity in preimplantation mouse embryos. A A Kiessling, H M Weitlauf J Exp Zool 1979 new
Trisodium phosphonoformate inhibits hepatitis B Dane particle DNA polymerase. E Nordenfelt, E Helgstrand, Bo Oberg Acta Pathol Microbiol Scand B 1979 new
Distinctive properties of mammalian DNA polymerases. D K Dube, Thomas A Kunkel, G Seal, Lawrence A Loeb Biochimica et biophysica acta 1979 new
Herpes simplex virus DNA synthesis in a partially purified soluble extract from infected cells. P F Pignatti, E Cassai, U Bertazzoni J Virol 1979 topics set
Herpes simplex virus DNA polymerase, thymidine kinase and deoxyribonuclease activities in cells infected with wild type, ultraviolet-irradiated and defective virus. Y Becker, B Gutter, Y Cohen, N Chejanovsky, S Rabkin, B Fridlender Arch Virol 1979 new
The delta subunit of Escherichia coli DNA polymerase III holoenzyme is the dnaX gene product. Ulrich Hübscher, Arthur Kornberg Proceedings of the National Academy of Sciences of the United States of America 1979 pols set
Proteolytic conversion of rat thymus DNA polymerase alpha to a more active form. P E Penner Can J Biochem 1979 new
Functions of DNA polymerases alpha, beta, and gamma in neurons during development. Ulrich Hübscher, C C Kuenzle, W Limacher, P Scherrer, Silvio Spadari Cold Spring Harbor symposia on quantitative biology 1979 topics set
DNA replication by bacteriophage T4 proteins. The T4 43, 32, 44--62, And 45 proteins are required for strand displacement synthesis at nicks in duplex DNA. Nancy G Nossal, B M Peterlin The Journal of biological chemistry 1979 complete
On the fidelity of DNA replication. Effect of divalent metal ion activators and deoxyrionucleoside triphosphate pools on in vitro mutagenesis. Thomas A Kunkel, Lawrence A Loeb The Journal of biological chemistry 1979 new
Antibody to B. subtilis DNA polymerase III: use in enzyme purification and examination of homology among replication-specific DNA polymerases. Marjorie H Barnes, Neal C Brown Nucleic acids research 1979 new
A rapid procedure for isolation of large quantities of Escherichia coli DNA polymerase I utilizing a lambdapolA transducing phage. W S Kelley, K H Stump The Journal of biological chemistry 1979 pols set
Functional roles of DNA polymerases beta and gamma. Ulrich Hübscher, C C Kuenzle, Silvio Spadari Proceedings of the National Academy of Sciences of the United States of America 1979 topics set
Error induction and correction by mutant and wild type T4 DNA polymerases. Kinetic error discrimination mechanisms. L K Clayton, Myron F Goodman, E W Branscomb, D J Galas The Journal of biological chemistry 1979 complete
Influence of various 2- and 2'-substituted polyadenylic acids on murine leukemia virus reverse transcriptase. Erik De Clercq, T Fukui, N Kakiuchi, M Ikehara, M Hattori, W Pfleiderer Cancer letters 1979 new
Further studies on partially purified calf thymus DNA polymerase a. K McKune, A M. Holmes Nucleic acids research 1979 new
The hepatitis B virus and its DNA polymerase: the prototype three-D virus. S Z Hirschman Mol Cell Biochem 1979 new
Regulation of DNA synthesis and DNA polymerase in rat pancreas. I. Glucocorticoid control in young animals. Yu Sam Kim, I Jatoi, Y Kim Exp Mol Pathol 1979 new
A simple and rapid purification method for Escherichia coli DNA polymerase I. G Rhodes, K D Jentsch, T M Jovin The Journal of biological chemistry 1979 pols set
DNA polymerase alpha, beta and gamma activities in ultraviolet irradiated CV-1 monkey cells. R Wicker, A I Scovassi, S Nocentini Nucleic acids research 1979 new
Purification and properties of DNA polymerase gamma from rabbit intestinal epithelial cells. Janusz A Siedlecki, B Z Zmudzka Acta Biochim Pol 1979 new
Enzymological characterization of KB cell DNA polymerase-alpha. III. The polymerization reaction with single-stranded DNA. Paul A Fisher, D Korn The Journal of biological chemistry 1979 new
Characterization of the ribonucleic acid primers and the deoxyribonucleic acid product synthesized by the DNA polymerase and gene 4 protein of bacteriophage T7. Louis J Romano, Charles C Richardson The Journal of biological chemistry 1979 new
DNA polymerase activity: a method of determining the infectivity of blood positive for anti-HBc. S H Ton, C G Lopez, H Hasnah Malays J Pathol 1979 new
A stimulatory factor for yeast DNA polymerase. L M Chang, K Lurie, Paolo Plevani Cold Spring Harbor symposia on quantitative biology 1979 new
Decreased UV mutagenesis in cdc8, a DNA replication mutant of Saccharomyces cerevisiae. Louise Prakash, D Hinkle, Satya Prakash Molecular & general genetics : MGG 1979 new
Diadenosine 5',5'''-P1,P4-tetraphosphate, a ligand of the 57-kilodalton subunit of DNA polymerase alpha. F Grummt, G Waltl, H M Jantzen, K Hamprecht, U Huebscher, C C Kuenzle Proceedings of the National Academy of Sciences of the United States of America 1979 new
Inhibition of DNA synthesis in BHK cells infected with western equine encephalitis virus. 2. Properties of the inhibitory factor of DNA polymerase induced in infected cells. S Koizumi, B Simizu, I Ishida, A Oya, Masami Yamada Virology 1979 new
Effect of phosphatidylcholine vesicles on the activity of DNA polymerase-alpha. S Capitani, G Mazzotti, R Jovine, S Papa, N M Maraldi, F A Manzoli Mol Cell Biochem 1979 new
Effect of aphidicolin on viral and human DNA polymerases. G Pedrali-Noy, Silvio Spadari Biochemical and biophysical research communications 1979 topics set
Novel properties of DNA polymerase beta with poly(rA).oligo(dT) template-primer. Shonen Yoshida, Masami Yamada, S Masaki J Biochem 1979 new
Characterization of a mutator DNA polymerase I from Salmonella typhimurium. M J Engler, M J Bessman Cold Spring Harbor symposia on quantitative biology 1979 new
Variation of DNA polymerase activities in chick neural retina as a function of age. D S Carré, C Pieau Differentiation 1979 new
Comparison of DNA polymerase activity and cell division in normal and delayed-implanting mouse embryos. H Weitlauf, A Kiessling, R Buschman J Exp Zool 1979 new
Changes in hepatitis B virus DNA polymerase in relation to the outcome of acute hepatitis type B. A Alberti, S Diana, A L Eddleston, R Williams Gut 1979 new
Aphidicolin resistant mutant of which DNA polymerase alpha is induced by this drug. M Nishimura, H Yasuda, S Ikegami, Mochihiko Ohashi, Masami Yamada Biochem Biophys Res Commun 1979 new
RNA-primed DNA synthesis by an enzyme preparation of calf thymus containing highly enriched RNA polymerase B and DNA polymerase. B Drescher, K Grade Acta Biol Med Ger 1979 new
Evidences for the function of DNA polymerase-beta in unscheduled DNA synthesis. E Wawra, I Dolejs Nucleic acids research 1979 new
T7-induced DNA polymerase. Characterization of associated exonuclease activities and resolution into biologically active subunits. S Adler, P Modrich The Journal of biological chemistry 1979 partial results
Deoxyribonucleic acid polymerase of bacteriophage T7. Characterization of the exonuclease activities of the gene 5 protein and the reconstituted polymerase. K Hori, D F Mark, Charles C Richardson The Journal of biological chemistry 1979 pols set
Hepatitis B e antigen, DNA polymerase activity, and infection of household contacts with hepatitis B virus. R P Perrillo, L Gelb, C Campbell, W Wellinghoff, F R Ellis, L Overby, R D Aach Gastroenterology 1979 new
Identification of a DNA polymerase beta-like form in Drosophila melanogaster adult flies. M Furia, L C Polito, G Locorotondo, P Grippo Nucleic acids research 1979 new
Presence of DNA in rubella variant with DNA polymerase activity. Mamoru Sato, Naoki Maeda, K Shirasuna, Hiromi Yoshida, T Yanagawa, Y Yura, T Miyazaki Arch Virol 1979 new
Additive effects of bleomycin and neocarzinostatin on degradation of DNA, inhibition of DNA polymerase beta, and cell growth. W E Müller, A Maidhof, J Arendes, W Geurtsen, R K Zahn, R Schmidseder Cancer research 1979 new
Mitochondrial DNA polymerase from Xenopus laevis oocytes. P Bazzicalupo Biochem Biophys Res Commun 1979 pols set
Interaction of Cibacron Blue F3GA with Escherichia coli DNA polymerase I and with T4 DNA polymerase. T D Lindell, B P Nichols, J E Donelson, E Stellwagen Biochimica et biophysica acta 1979 pols set
Prevalence of anti-HBc in Malaysian male blood donors and its correlation with DNA polymerase activity. S H Ton, C G Lopez, H Hasnah Southeast Asian J Trop Med Public Health 1979 new
Comparison of the A-T rich regions and the Bacillus subtilis RNA polymerase binding sites in phage phi 29 DNA. J M Sogo, P Rodeño, T Koller, E Viñuela, Margarita Salas Nucleic acids research 1979 pols set
Detection and characterization of DNA polymerase from Trypanosoma brucei. D K Dube, R O Williams, G Seal, S C Williams Biochimica et biophysica acta 1979 new
Prevalence of HBeAg, anti-HBe and Dane particle-associated DNA polymerase activity in asymptomatic carriers of HBsAg. A Zanetti, P Ferroni, F Bergamini, F Legnani Ric Clin Lab 1979 new
Purification of gene 41 protein of bacteriophage T4. C F Morris, L A Moran, B M Alberts The Journal of biological chemistry 1979 complete
A new approach to DNA polymerase kinetics. F Bernardi, M Saghi, M Dorizzi, J Ninio Journal of molecular biology 1979 new
Requirements for synthesis of ribonucleic acid primers during lagging strand synthesis by the DNA polymerase and gene 4 protein of bacteriophage T7. Louis J Romano, Charles C Richardson The Journal of biological chemistry 1979 pols set
Inhibition of human neuroblastoma DNA polymerase activities by plant lectins and toxins. P Bhattacharya, I Simet, S Basu Proceedings of the National Academy of Sciences of the United States of America 1979 new
Role of polymeric forms of the bacteriophage phi X174 coded gene A protein in phi XRFI DNA cleavage. J E Ikeda, A Yudelevich, N Shimamoto, Jerard Hurwitz The Journal of biological chemistry 1979 pols set
Characterization of lambdapolA transducing phages; effective expression of the E. coli polA gene. N E Murray, W S Kelley Mol Gen Genet 1979 pols set
Methylation-dependent DNA synthesis in Escherichia coli mediated by DNA polymerase I. C Lark J Bacteriol 1979 new
The mode of inhibitory action by aphidicolin on eukaryotic DNA polymerase alpha. M Oguro, C Suzuki-Hori, H Nagano, Y Mano, S Ikegami Eur J Biochem 1979 new
DNA polymerase activity in proliferating and antigen-stimulated tissues. M G Battelli, C Franceschi, F Novello, F Stirpe Exp Mol Pathol 1979 new
DNA polymerase-alpha from regenerating rat liver. Catalytic properties of the highly purified enzyme. O Fichot, M Pascal, M Mechali, A M de Recondo Biochimica et biophysica acta 1979 pols set
DNA polymerase beta from brain neurons is a repair enzyme. J Waser, Ulrich Hübscher, C C Kuenzle, Silvio Spadari European journal of biochemistry / FEBS 1979 topics set
A study on the unprimed poly (dA-dT) synthesis catalyzed by preparations of E. coli DNA polymerase I. I A Nazarenko, L E Bobko, A G Romashchenko, Y L Khripin, R I Salganik Nucleic acids research 1979 pols set
Radioimmunoassay in the detection of the hepatitis B e antigen/antibody system in asymptomatic carriers of hepatitis B surface antigen. Correlation with serum Dane particle associated DNA polymerase activity. G Pastore, A R Zanetti, P Ferroni, P Dentico, G Angarano, O Schiraldi Infection 1979 new
DNA replication with bacteriophage T4 proteins. Purification of the proteins encoded by T4 genes 41, 45, 44, and 62 using a complementation assay. Nancy G Nossal The Journal of biological chemistry 1979 complete
On the fidelity of DNA replication. Accuracy of Escherichia coli DNA polymerase I. S S Agarwal, D K Dube, Lawrence A Loeb The Journal of biological chemistry 1979 pols set
In vivo interactions of genes and proteins in DNA replication and recombination of phage T4. G Mosig, A Luder, G Garcia, R Dannenberg, S Bock Cold Spring Harbor symposia on quantitative biology 1979 complete
The effect of template secondary structure on vaccinia DNA polymerase. M D Challberg, Paul T Englund The Journal of biological chemistry 1979 pols set
Further characterization of a cell-free system for measuring replicative and repair DNA synthesis with cultured human fibroblasts and evidence for the involvement of DNA polymerase alpha in DNA repair. G Ciarrocchi, J G Jose, Stuart Linn Nucleic acids research 1979 new
Mouse DNA polymerase alpha. Subunit structure and identification of a species with associated exonuclease. Y C Chen, E W Bohn, S R Planck, Samuel H Wilson The Journal of biological chemistry 1979 new
Variation of two forms of DNA polymerase-alpha during a HeLa cell cycle. Y Ono, Takemi Enomoto, Masami Yamada Gann = Gan 1979 pols set
Reverse transcriptase-associated ribonuclease H does not require zinc for catalysis. Mukund J Modak, Aashish Srivastava The Journal of biological chemistry 1979 new
Inhibition of DNA synthesis in BHK cells infected with western equine encephalitis virus. 1. Induction of an inhibitory factor of cellular DNA polymerase activity. S Koizumi, B Simizu, Keiji Hashimoto, A Oya, Masami Yamada Virology 1979 new
Properties of herpes simplex virus DNA polymerase and characterization of its associated exonuclease activity. K W Knopf Eur J Biochem 1979 new
Aphidicolin inhibits eukaryotic DNA replication and repair --- implications for involvement of DNA polymerase alpha in both processes. N A Berger, K K Kurohara, S J Petzold, G W Sikorski Biochem Biophys Res Commun 1979 new
Purification of the gene 43, 44, 45, and 62 proteins of the bacteriophage T4 DNA replication apparatus. C F Morris, H Hama-Inaba, D Mace, N K Sinha, B Alberts The Journal of biological chemistry 1979 complete
The functional roles of mammalian DNA polymerase. A Weissbach Arch Biochem Biophys 1979 pols set
Reverse transcriptase-associated RNase H. Part IV. Pyrophosphate does not inhibit RNase H activity of AMV DNA polymerase. Aashish Srivastava, Mukund J Modak Biochemical and biophysical research communications 1979 new
Discrimination of reverse transcriptase from cellular DNA polymerase by kinetic analysis. K Ono, A Ohashi, A Yamamoto, Akio Matsukage, N Nishioka, Tomosaburo Takahashi, C Nakayama, Mineo Saneyoshi Cellular and molecular biology, including cyto-enzymology 1979 new
Properties of herpesvirus-specific thymidine kinase, DNA polymerase and DNase and their implication in the development of specific antiherpes agents. Yung-Chi Cheng, P J Hoffmann, M Ostrander, S Grill, S Caradonna, J Tsou, J Y Chen, M R Gallagher, T D Flanagan Adv Ophthalmol 1979 new
Difference in the mechanisms of poly(dT) synthesis by DNA polymerases beta and gamma. Akio Matsukage, Masatoyo Nishizawa, Tomonori Takahashi Journal of biochemistry 1979 new
On the fidelity of DNA replication. Metal activation of Escherichia coli DNA polymerase I. M A Sirover, D K Dube, Lawrence A Loeb The Journal of biological chemistry 1979 pols set
Decreased fidelity of DNA polymerase activity during N-2-fluorenylacetamide hepatocarcinogenesis. J Y Chan, F F Becker Proceedings of the National Academy of Sciences of the United States of America 1979 new
On the fidelity of DNA replication. Studies with human placenta DNA polymerases. G Seal, C W Shearman, Lawrence A Loeb The Journal of biological chemistry 1979 new
Deoxyribonucleic acid polymerase of bacteriophage T7. Purification and properties of the phage-encoded subunit, the gene 5 protein. K Hori, D F Mark, Charles C Richardson The Journal of biological chemistry 1979 partial results
Deoxyribonucleotide synthesis and DNA polymerase activity in plant cells (Vicia faba and Glycine max). B Hovemann, H Follmann Biochimica et biophysica acta 1979 new
Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate. Phillip A Furman, M H St Clair, J A Fyfe, J L Rideout, P M Keller, G B Elion J Virol 1979 new
Utilization of 2'-deoxy-6-thioguanosine 5'-triphosphate in DNA synthesis in vitro by DNA polymerase alpha from calf thymus. Shonen Yoshida, Masami Yamada, S Masaki, Mineo Saneyoshi Cancer research 1979 new
Absence of plasmid-mediated DNA polymerase activity from UV-induced strains of Escherichia coli [proceedings]. C Upton, R J Pinney J Pharm Pharmacol 1979 new
Fidelity of replication of phage phi X174 DNA by DNA polymerase III holoenzyme: spontaneous mutation by misincorporation. A R Fersht Proceedings of the National Academy of Sciences of the United States of America 1979 new
RNA polymerase binding sites and transcription map of the DNA of Bacillus subtilis phage phi29. J M Sogo, M R Inciarte, J Corral, E Viñuela, Margarita Salas Journal of molecular biology 1979 pols set
Age-dependent gene induction in quail oviduct. VII. Alteration of DNA polymerase activities in response to progesterone treatment. W E Müller, R K Zahn Mech Ageing Dev 1979 new
Positive regulation of T-even-phage DNA replication by the DNA-delay protein of gene 39. W M Huang Cold Spring Harbor symposia on quantitative biology 1979 complete
Phosphonoformate inhibits reverse transcriptase. B Sundquist, Bo Oberg The Journal of general virology 1979 new
Regulation of expression of type C virion DNA polymerase (reverse transcriptase) in human x mouse and human x rat hybrid cells. John D Minna, T H Marshall, S H Brown, R D Burk, R S Lemons, Samuel H Wilson Somatic cell genetics 1979 new
The effects of the ultraviolet-protecting plasmids pKM101 and R205 on DNA polymerase I activity in Escherichia coli K-12. J W Kronish, Graham C Walker Mutation research 1979 new
Inhibition of the activity of DNA polymerase alpha by 2',3'-dideoxythymidine 5'-triphosphate. K Ono, M Ogasawara, Akio Matsukage Biochem Biophys Res Commun 1979 new
Recognition of structure of 5-halogenated derivatives of ara-UTP by DNA polymerase gamma and reverse transcriptase. K Ono, M Ogasawara, A Ohashi, Akio Matsukage, Tomonori Takahashi, C Nakayama, Mineo Saneyoshi Nucleic Acids Symp Ser 1979 new
The mode of inhibitory action by pyridoxal 5-phosphate on DNA polymerase-alpha and -beta. M Oguro, H Nagano, Y Mano Nucleic acids research 1979 new
Isolation of a DNA polymerase alpha-associated regulatory protein from calf thymus. J A Steinberg, M Otten, G B Grindey Cancer research 1979 new
Enzymological characterization of DNA polymerase alpha. Basic catalytic properties processivity, and gap utilization of the homogeneous enzyme from human KB cells. Paul A Fisher, Teresa S-F Wang, D Korn The Journal of biological chemistry 1979 partial results
Mechanism of action of the anthracycline anti-tumor antibiotics, doxorubicin, daunomycin and rubidazone: preferential inhibition of DNA polymerase alpha. G P Sartiano, W E Lynch, W D Bullington J Antibiot (Tokyo) 1979 new
Probing DNA replication mechanisms with the T4 bacteriophage in vitro system. Chin-Chi Liu, R L Burke, U Hibner, J Barry, B Alberts Cold Spring Harbor symposia on quantitative biology 1979 complete
Purification and properties of the deoxyribonucleic acid polymerase induced by vaccinia virus. M D Challberg, Paul T Englund The Journal of biological chemistry 1979 topics set
Thymidine kinase and DNA polymerase activity during postnatal growth of the epididymal fat pad. M P Cleary, B E Klein, J Brasel, M R Greenwood J Nutr 1979 new
Purification and characterization of bovine leukemia virus DNA polymerase. B Drescher, H Rössler, P Venker, W Wittmann Arch Geschwulstforsch 1979 new
Interaction of human DNA polymerase beta with ions of copper, lead, and cadmium. E A Popenoe, M A Schmaeler Arch Biochem Biophys 1979 pols set
A mammalian DNA- mutant decreasing nuclear DNA polymerase alpha activity at nonpermissive temperature. Y J Tsai, Fumio Hanaoka, M M Nakano, Masami Yamada Biochem Biophys Res Commun 1979 new
Characterization of an alpha-like DNA polymerase from Bombyx mori silkglands. M de Turenne Biochimie 1978 new
Variation of DNA polymerase and RNA polymerase activities in cells infected with herpes simplex virus type 1. W E Müller, R K Zahn, D Falke Virology 1978 new
Studies on the purification and properties of a 6.8-S DNA polymerase activity found in calf-thymus DNA polymerase-alpha fraction. I P Hesslewood, A M. Holmes, W F Wakeling, I R. Johnston Eur J Biochem 1978 new
Inducible DNA polymerase in cultured rat fibroblasts treated with skin carcinogen mitomycin C. V M Bozhkov, T V Barskaya, I I Fridlyanskaya, N V Tomilin FEBS letters 1978 new
Filtration and immunoprecipitation in the elimination of DNA polymerase activity associated with bacterial contamination of sera positive for hepatitis B e antigen and its corresponding antibody. R P Perrillo, L D Gelb, W Wellinghoff, R D Aach J Infect Dis 1978 new
Gliotoxin analogues as inhibitors of reverse transcriptase. 2. Resolution and X-ray crystal structure determination. H C Ottenheijm, J D Herscheid, M W Tijhuis, R J Nivard, Erik De Clercq, P A Prick Journal of medicinal chemistry 1978 new
Gliotoxin analogues as inhibitors of reverse transcriptase. 1. Effect of lipophilicity. H C Ottenheijm, J D Herscheid, M W Tijhuis, M Oosterbaan, Erik De Clercq Journal of medicinal chemistry 1978 new
[DNA binding protein and activator protein (s) of DNA polymerase (author's transl)]. A Ichikawa Seikagaku 1978 new
DNA polymerase activity in muscle cultures. G C Yeoh, D Greenstein, H Holtzer J Cell Biol 1978 new
A low molecular weight DNA polymerase beta in the sea urchin Strongylocentrotus purpurantus. Partial purification, properties, and changes in development. P M Hobart, A A Infante The Journal of biological chemistry 1978 new
[Purification of DNA polymerase from Proteus mirabilis]. R Nüske, J Bieber, U Wähnert, H Venner Z Allg Mikrobiol 1978 new
DNA polymerase-gamma is localized in mitochondria. Shigeru Tanaka, K Koike Biochem Biophys Res Commun 1978 new
Inhibition of deoxyribonucleic acid polymerases from human cells and from simian sarcoma virus by pyran. R Dicioccio, B I Srivastava Biochem J 1978 topics set
Thymidine kinase and DNA polymerase activity in normal and zinc deficient developing rat embryos. J R Duncan, L S Hurley Proc Soc Exp Biol Med 1978 new
Association of DNA polymerase with nucleosomes from mammalian cell chromatin. E J Schlaeger, H J van Telgen, K H Klempnauer, R Knippers Eur J Biochem 1978 new
Analysis of a T4 DNA replication protein complex. Studies of the DNA recognition site for T4 gene 44/62 and 45 protein-catalyzed ATP hydrolysis. J R Piperno, R G Kallen, B M Alberta The Journal of biological chemistry 1978 complete
Effect of 2',3'-dideoxythymidine-5'-triphosphate on HeLa cell in vitro DNA synthesis: evidence that DNA polymerase alpha is the only polymerase required for cellular DNA replication. M A Waqar, M J Evans, J A Huberman Nucleic acids research 1978 topics set
A Neurospora DNA polymerase. Its isolation and partial characterization. S El-Assouli, N C Mishra Naturwissenschaften 1978 new
DNA synthesis and DNA polymerase activity in Leydig cells of diethylstilbestrol-stimulated mouse testes. S L Spruance, B Wilcox, O C Richards, D N Foster, R A Huseby, L T Samuels Cancer research 1978 new
Purification and properties of DNA polymerase-beta from guinea pig liver. Thomas A Kunkel, J E Tcheng, R R Meyer Biochimica et biophysica acta 1978 new
Gene 4 protein of bacteriophage T7. Purification physical properties, and stimulation of T7 DNA polymerase during the elongation of polynucleotide chains. R Kolodner, Y Masamune, J E LeClerc, Charles C Richardson The Journal of biological chemistry 1978 pols set
beta-Lapachone, an inhibitor of oncornavirus reverse transcriptase and eukaryotic DNA polymerase-alpha. Inhibitory effect, thiol dependence and specificity. A R Schuerch, W Wehrli Eur J Biochem 1978 new
The inhibition of mitochondrial DNA polymerase gamma from animal cells by intercalating drugs. L Tarrago-Litvak, O Viratelle, D Darriet, R Dalibart, P V Graves, Simon Litvak Nucleic acids research 1978 new
Diagnosis of hepatitis B by Dane particle associated DNA polymerase assay. R Cappel, F De Cuyper, D Van Beers J Med Virol 1978 new
Gene 4 protein of bacteriophage T7. Characterization of the product synthesized by the T7 DNA polymerase and gene 4 protein in the absence of ribonucleoside 5'-triphosphates. R Kolodner, Charles C Richardson The Journal of biological chemistry 1978 pols set
DNA replication in human lymphocytes during aging. S S Agarwal, M Tuffner, Lawrence A Loeb Journal of cellular physiology 1978 new
Detection of a DNA polymerase beta stimulating protein in HeLa cell nuclear extracts. W T Blue, A Weissbach Biochem Biophys Res Commun 1978 new
On the processive mechanism of Escherichia coli DNA Polymerase I. The polA5 mutation. S W Matson, F N Capaldo-Kimball, Robert A Bambara The Journal of biological chemistry 1978 pols set
Adenovirus type 12 tumor antigen. I. Separation from DNA polymerase alpha and immunoprecipitation of tumor-antigen polypeptides. K K Biron, M P Morrongiello, J Rasková, K Raska Virology 1978 new
DNA polymerase profile during the mosquito life span. W Mastropaolo, C A Lang Exp Gerontol 1978 new
Inhibition of activities of DNA polymerase alpha, beta, gamma, and reverse transcriptase of L1210 cells by phosphonoacetic acid. H S Allaudeen, J R Bertino Biochimica et biophysica acta 1978 new
DNA polymerase and mutation. B Bridges Nature 1978 new
Effect of heparin or removal of lysine-rich histone fraction on the poly (ADP-ribose) polymerase, DNA polymerase and template activity of isolated swine aortic nuclei. K Janakidevi Exp Cell Res 1978 new
Hepatitis B core particles with endogenous DNA polymerase activity from chimpanzee liver. H Onda, S Matsuda, Y Oka Intervirology 1978 new
Ribonucleotidyl transferase in preparations of partially purified DNA polymerase alpha of the sea urchin. P W Morris, F M Racine Nucleic acids research 1978 new
The detection of DNA polymerase activity in the diagnosis of HBV infection. C R Howard J Med Virol 1978 new
Glycolipids stimulate DNA polymerase activity in a DNA-membrane fraction and in a partially purified polymerase system extracted from pneumococci. A Zerial, I Gelman, W Firshein J Bacteriol 1978 new
Site specificity and variability in the mutator and antimutator effects of phage T4 gene 43 mutants. A Ronen, C Halevy, N Kass Genetics 1978 complete
Bacillus subtilis dnaF: a mutation of the gene specifying the structure of DNA polymerase III. M J Vrooman, Marjorie H Barnes, Neal C Brown Mol Gen Genet 1978 new
A nuclear DNA polymerase in bull spermatozoa. J M Richards, S S Witkin J Reprod Fertil 1978 new
A low molecular weight DNA polymerase from ovaries of the frog Xenopus laevis. DNA polymerase-beta (ovarian). H Joenje, R M Benbow The Journal of biological chemistry 1978 new
DNA-dependent DNA polymerase species in male germ cells of the mouse. P Grippo, R Geremia, G Locorotondo, V Monesi Cell Differ 1978 new
Replication of plasmid R6K in DNA polymerase deficient mutants of Escherichia coli. M Włodarczyk, M Bednarska Acta Microbiol Pol 1978 pols set
Molecular size and fidelity of DNA polymerase alpha from the regenerating liver of the rat. J G Salisbury, P J O'Connor, R Saffhill Biochimica et biophysica acta 1978 new
Role of DNA polymerase gamma in adenovirus DNA replication. Peter C van der Vliet, M M Kwant Nature 1978 new
An exonuclease activity associated with DNA polymerase I of Micrococcus radiodurans. S Kitayama, Y Ishizaka, S Miyai, A Matsuyama Biochimica et biophysica acta 1978 new
Incomplete inactivation of hepatitis B virus after heat treatment at 60 C for 10 hours. T Shikata, T Karasawa, K Abe, Tomonori Takahashi, M Mayumi, T Oda The Journal of infectious diseases 1978 pols set
Relationship of Bacillus subtilis DNA polymerase III to bacteriophage PBS2-induced DNA polymerase and to the replication of uracil-containing DNA. R A Hitzeman, A R Price J Virol 1978 new
[DNA-polymerase activity of the nuclei of lymphocytes from the lymph of normal cattle and cattle with lymphatic leukemia]. N A Kovalevskiĭ, Iu M Azizov, A D Belov Izv Akad Nauk SSSR Biol 1978 new
DNA polymerase alpha is associated with replicating SV40 nucleoprotein complexes. B Otto, Ellen Fanning Nucleic acids research 1978 new
Differential inhibition of mammalian DNA polymerases alpha, beta and gamma and herpes simplex virus-induced DNA polymerase by the 5'-triphosphates of arabinosyladenine and arabinosylcytosine. C M Reinke, J C Drach, C Shipman, A Weissbach IARC Sci Publ 1978 pols set
In vitro transcription of reconstituted 35s RNA.tRNAtrp template.primer complexes by the avian oncornavirus DNA polymerase. Effect of temperature on the size of the DNA transcripts. J P Leis, R E Smith, P Dierks, J T Parsons, M S Collett, A J Faras Virology 1978 new
Replication of poly dA and poly rA by a drosophila DNA polymerase. C L Brakel, A B Blumenthal Nucleic acids research 1978 new
An ATP stimulation of T4 DNA polymerase mediated via T4 gene 44/62 and 45 proteins. The requirement for ATP hydrolysis. J R Piperno, B M Alberts The Journal of biological chemistry 1978 complete
Inhibition of hepatitis B DNA polymerase by intercalating agents. S Z Hirschman, E Garfinkel Nature 1978 new
Inhibition of mouse myeloma DNA polymerase alpha by 5-triphosphates of 1-beta-D-arabinofuranosylthymine and 1-beta-D-arabinofuranosylcytosine. A Mutsukage, Tomonori Takahashi, C Nakayama, Mineo Saneyoshi J Biochem 1978 new
Inhibitory effect of 1-beta-D-arabinofuranosylthymine 5'-triphosphate and 1-beta-D-arabinofuranosylcytosine 5'-triphosphate on DNA polymerases from murine cells and oncornavirus. Akio Matsukage, K Ono, A Ohashi, Tomosaburo Takahashi, C Nakayama, Mineo Saneyoshi Cancer research 1978 new
Separation of two forms of HeLa DNA polymerase alpha with different binding affinity to DNA. Y Ono, F E Hanaoka, Masami Yamada Gann 1978 new
Template-specific requirements for DNA synthesis by the Mason-Pfizer monkey virus DNA polymerase: unique aspects. S L Marcus, N H Sarkar, Mukund J Modak Biochimica et biophysica acta 1978 new
Enzymatic determinants of DNA polymerase accuracy. Theory of coliphage T4 polymerase mechanisms. D J Galas, E W Branscomb Journal of molecular biology 1978 new
Molecular heterogeneity of DNA polymerase alpha from P815 mouse mastocytoma cells. F Bieri-Bonniot, A R Schuerch FEBS letters 1978 new
On the processive mechanism of Escherichia coli DNA polymerase I. Quantitative assessment of processivity. Robert A Bambara, D Uyemura, T Choi The Journal of biological chemistry 1978 partial results
Studies on Epstein-Barr virus DNA polymerase activities in various human lymphoblastoid cell lines. T Ooka, J Daillie, O Costa, G Lenoir IARC Sci Publ 1978 new
Inhibition of herpesvirus replication and herpesvirus-induced deoxyribonucleic acid polymerase by phosphonoformate. J M Reno, L F Lee, J A Boezi Antimicrob Agents Chemother 1978 new
Use of insoluble heparin for isolation of DNA polymerase enzymes from murine myeloma. B A Brennessel, D P Buhrer, A A Gottlieb Anal Biochem 1978 new
Reverse transcriptase-associated RNase H activity. II. Inhibition by natural and synthetic RNA. S L Marcus, S W Smith, Mukund J Modak Journal of virology 1978 new
Mutagenic DNA repair in Escherichia coli. VIII. Involvement of DNA polymerase III in constitutive and inducible mutagenic repair after ultraviolet and gamma irradiation. B A Bridges, R P Mottershead Mol Gen Genet 1978 new
D(M6ATP) as a probe of the fidelity of base incorporation into polynucleotides by Escherichia coli DNA polymerase I. J D Engel, Peter H von Hippel The Journal of biological chemistry 1978 pols set
Characterization of the Bacillus subtilis bacteriophage PBS2-induced DNA polymerase and its associated exonuclease activity. R A Hitzeman, A R Price The Journal of biological chemistry 1978 new
Differential activation of hepatitis B DNA polymerase by detergent and salt. S Z Hirschman, M Gerber, E Garfinkel J Med Virol 1978 new
DNA polymerase of phage T4 antimutator mutant CB121. A defective zinc metalloenzyme? C Schroeder, J Jantschak FEBS letters 1978 new
Aphidicolin prevents mitotic cell division by interfering with the activity of DNA polymerase-alpha. S Ikegami, Takahiko Taguchi, Mochihiko Ohashi, M Oguro, H Nagano, Y Mano Nature 1978 new
Changes of mitochondrial DNA polymerase-gamma activity in synchronized mouse cell cultures. K Radsak, E Schütz Eur J Biochem 1978 new
Selective response of DNA polymerase beta to bleomycin-induced breaks in DNA. M L Coetzee, R Chou, P Ove Cancer research 1978 new
Effect of caffeine on DNA polymerase I from Escherichia coli: studies in vitro and in vivo. K A Solberg, S Ovrebø, R K Kleppe, K Kleppe Mutation research 1978 pols set
Effect of herpes simplex virus type 1 infection on the cellular DNA polymerase activities of mouse cell cultures. K Radsak The Journal of general virology 1978 new
HBsAg-positive chronic liver disease: inhibition of DNA polymerase activity by vidarabine. R G Chadwick, M F Bassendine, E M Crawford, H C Thomas, S Sherlock Br Med J 1978 new
Uracil incorporation: a source of pulse-labeled DNA fragments in the replication of the Escherichia coli chromosome. BK Tye, J Chien, I. Robert Lehman, BK Duncan, HR Warner Proceedings of the National Academy of Sciences of the United States of America 1978 new
Involvement of DNA polymerase alpha in simian virus 40 DNA replication. H J Edenberg, S Anderson, M L DePamphilis The Journal of biological chemistry 1978 new
Absolute configuration of the diastereomers of adenosine 5'-O-(1-thiotriphosphate): consequences for the stereochemistry of polymerization by DNA-dependent RNA polymerase from Escherichia coli. Peter M J Burgers, F Eckstein Proceedings of the National Academy of Sciences of the United States of America 1978 pols set
Synthesis of viral and host DNA in isolated chromatin from herpes simplex virus-infected HeLa cells. Masami Yamada, G Brun, A Weissbach Journal of virology 1978 new
Bacillus subtilis bacteriophage PBS2-induced DNA polymerase. Its purification and assay characteristics. R A Hitzeman, A R Price The Journal of biological chemistry 1978 new
Purification and characterization of varicella-zoster virus-induced DNA polymerase. E C Mar, Y S Huang, E S Huang J Virol 1978 partial results
Two Epstein-Barr virus-associated DNA polymerase activities. S R Goodman, C Prezyna, W C Benz The Journal of biological chemistry 1978 new
Mutagenesis during in vitro DNA synthesis. L A Weymouth, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1978 pols set
A rapid technique to separate DNA polymerase-alpha and -beta activity from a cytosol extract. M Duguet, M Méchali, J M Rossignol Anal Biochem 1978 new
Trisodium phosphonoformate, a new antiviral compound. E Helgstrand, B Eriksson, N G Johansson, B Lannerö, A Larsson, A Misiorny, J O Norén, B Sjöberg, K Stenberg, G Stening, S Stridh, Bo Oberg Science 1978 new
HeLa DNA polymerase alpha activity in vitro: specific stimulation by a non-enzymic protein factor. B Novak, E F Baril Nucleic acids research 1978 topics set
Nucleotide clusters in deoxyribonucleic acids: sequence analysis of DNA using pyrimidine oligonucleotides as primers in the DNA polymerase I repair reaction. J S Kaptein, J H Spencer Biochemistry 1978 pols set
Reversible inhibition of the induction of DNA polymerase of herpes simplex virus type 2 in HeLa cells. H Nishigori, Mamoru Sato, C Nishimura Arch Virol 1978 new
Purification and properties of mosquito DNA polymerase. W Mastropaolo, C A Lang The Journal of biological chemistry 1978 new
Age-dependent stimulation by estradiol-17beta of DNA polymerase alpha in immature rat uterus. M D Walker, A M Kaye, B R Fridlender FEBS letters 1978 new
DNA polymerase I-mediated ultraviolet repair synthesis in toluene-treated Escherichia coli. J W Dorson, Robb E Moses The Journal of biological chemistry 1978 new
DNA polymerase activity of lymphocyte nuclei of cattle lymph in the normal state and in lympholeukemia. N A Kovalevskii, Y M Azizov, A D Belov Biol Bull Acad Sci USSR 1978 new
The involvement of DNA polymerase I in the postreplication repair of ultraviolet radiation-induced damage in Escherichia coli K-12. T R Barfknecht, K C Smith Mol Gen Genet 1978 new
Interaction of a mammalian single strand specific DNA binding protein with DNA polymerase alpha. A Richter, R Knippers, B Otto FEBS letters 1978 new
Isolation of a herpesvirus-specific DNA polymerase from tissues of an American patient with Burkitt lymphoma. H S Allaudeen, J R Bertino Proceedings of the National Academy of Sciences of the United States of America 1978 new
Replication of nondefective parvoviruses: lack of a virion-associated DNA polymerase. C Pritchard, J T Patton, R C Bates, E R Stout J Virol 1978 new
Comparison of DNA polymerase alpha and delta from bone marrow. J J Byrnes, V L Black Biochemistry 1978 new
Estrogen stimulation of DNA-dependent DNA polymerase activity in immature rat uterus. J N Harris, J Gorski Mol Cell Endocrinol 1978 new
Differential susceptibilities of DNA polymerases-alpha and -beta to polyanions. T Shimada, Masami Yamada, M Miwa, H Nagano, Y Mano Nucleic acids research 1978 topics set
10-S DNA polymerase from calf thymus which copies both poly(rA) . oligo(dT) and activated DNA. S Masaki, Shonen Yoshida Biochimica et biophysica acta 1978 new
Specific effect of zinc ions on DNA polymerase activity of avian myeloblastosis virus. P R Palan, M L Eidinoff Mol Cell Biochem 1978 new
Replication of bacteriophage M13. XIV. Differential inhibition of the replication of M13 and M13 miniphage in a mutant of Escherichia coli defective in the 5' leads to 3' exonuclease associated with DNA polymerase I. T C Chen, D S Ray J Virol 1978 new
Mechanisms of selective inhibition of 3' to 5' exonuclease activity of Escherichia coli DNA polymerase I by nucleoside 5'-monophosphates. B G Que, Kathleen M Downey, Antero G So Biochemistry 1978 pols set
Characterization of a protein covalently linked to the 5' termini of the DNA of Bacillus subtilis phage phi29. Margarita Salas, R P Mellado, E Viñuela Journal of molecular biology 1978 pols set
Mechanism of ultraviolet-induced mutagenesis: extent and fidelity of in vitro DNA synthesis on irradiated templates. Giuseppe Villani, S Boiteux, M Radman Proceedings of the National Academy of Sciences of the United States of America 1978 new
Mapping unintegrated avian sarcoma virus DNA: termini of linear DNA bear 300 nucleotides present once or twice in two species of circular DNA. P R Shank, Stephen H Hughes, H J Kung, J E Majors, N Quintrell, R V Guntaka, J M Bishop, H E Varmus Cell 1978 new
Comparison of DNase, DNA-polymerase and RNA-polymerase activities present in the DNA-binding proteins of normal human dermis, epidermis, horny layer and psoriatic scales. G Reimer, E J Zöllner, M Reitz, U Schwulera, G Leonhardi Arch Dermatol Res 1978 new
Aphidicolin: a specific inhibitor of DNA polymerases in the cytosol of rat liver. Mochihiko Ohashi, Takahiko Taguchi, S Ikegami Biochemical and biophysical research communications 1978 topics set
Persistent infection of primary human cell cultures with rubella variant carrying DNA Polymerase activity. N Sato Mmaeda, Naoki Maeda, M Urade, M Kuribayashi, K Shirasuna, Hiromi Yoshida, T Miyazaki Arch Virol 1978 new
DNA polymerase alpha, beta and gamma activities in rabbit spleen cell populations stimulated by various doses of concanavalin A. Silvio Spadari, Giuseppe Villani, N Hardt Exp Cell Res 1978 new
DNA polymerase I-mediated repair of 365 nm-induced single-strand breaks in the DNA of Escherichia coli. R D Ley, B A Sedita, E Boye Photochem Photobiol 1978 pols set
Detection of a DNA-binding factor associated with mammalian DNA polymerase-alpha. M Méchali, A M de Recondo Biochem Biophys Res Commun 1978 pols set
Three forms of DNA polymerase from Drosophila melanogaster embryos. Purification and properties. C L Brakel, A B Blumenthal Eur J Biochem 1978 new
Separation of the enzyme catalyzing polymerization of deoxyribonucleoside diphosphates from the preparations of Escherichia coli DNA polymerase I. I A Nazarenko, V A Potapov, A G Romaschenko, R I Salganik FEBS letters 1978 pols set
DNA sequencing by partial ribosubstitution. Wayne M Barnes Journal of molecular biology 1978 pols set
DNA polymerase activities in differentiating mouse neuroblastoma N-18 cells. P Bhattacharya, S Basu Proceedings of the National Academy of Sciences of the United States of America 1978 topics set
Effect of glucosamine on virus production and antigen expression in avian sarcoma virus-transformed cells. E Israel, R Mandeville, Mark A. Wainberg Canadian journal of microbiology 1978 new
Induction of spleen cell growth and DNA polymerase activity by Corynebacterium parvum. Y Maruyama, M S Coleman Cancer research 1978 new
Apparent suicidal inactivation of DNA polymerase by adenosine 2',3'-riboepoxide 5'-triphosphate. M M Abboud, W J Sim, Lawrence A Loeb, A S Mildvan The Journal of biological chemistry 1978 pols set
Selective inhibition of herpes simplex virus type 1 DNA polymerase by zinc ions. B Fridlender, N Chejanovsky, Y Becker Virology 1978 new
DNA polymerase alpha and beta in the California urchin. F M Racine, P W Morris Nucleic acids research 1978 new
Inhibition of human seminal fluid DNA polymerase by an IgG fraction of seminal plasma from vasectomized men. P J Higgins, S S Witkin, A Bendich J Reprod Fertil 1978 new
DNA polymerase gamma of rabbit intestinal epithelial cells. J Kamać, Janusz A Siedlecki, B Z Zmudzka Acta Biochim Pol 1977 new
Inactivation of avian myeloblastosis virus DNA polymerase by specific binding of pyridoxal 5'-phosphate to deoxynucleoside triphosphate binding site. T S Papas, T W Pry, D J Marciani The Journal of biological chemistry 1977 new
Multiple forms of Drosophila embryo DNA polymerase: evidence for proteolytic conversion. C L Brakel, A B Blumenthal Biochemistry 1977 new
Selective inhibition of in vitro DNA synthesis dependent on phiX174 compared with fd DNA. I. Protein requirements for selective inhibition. R Vicuna, Jerard Hurwitz, S Wallace, M Girard The Journal of biological chemistry 1977 pols set
Selective inhibition of phiX RFII compared with fd RFII DNA synthesis in vitro. II. Resolution of discrimination reaction into multiple steps. R Vicuna, J E Ikeda, Jerard Hurwitz The Journal of biological chemistry 1977 new
In vitro inhibition of viral DNA polymerase activity by litmomycin. M L Sethi J Pharm Sci 1977 new
Specific inhibition of DNA polymerase-associated RNase H by DNA. Mukund J Modak, S L Marcus Journal of virology 1977 new
Inhibitors of Bacillus subtilis DNA polymerase III. Structure-activity relationships of 6-(phenylhydrazino)uracils. George E Wright, Neal C Brown J Med Chem 1977 pols set
Correlation of e antigen, DNA polymerase activity, and Dane particles in chronic benign and chronic active type B hepatitis infections. M J Tong, D Stevenson, I Gordon J Infect Dis 1977 new
Studies of an Epstein-Barr virus-induced DNA polymerase. R L Miller, R Glaser, F Rapp Virology 1977 new
Adriamycin interactions with T4 DNA polymerase. Two modes of template-mediated inhibition. Myron F Goodman, G M Lee The Journal of biological chemistry 1977 complete
On the fidelity of DNA replication. Effect of metal activators during synthesis with avian myeloblastosis virus DNA polymerase. M A Sirover, Lawrence A Loeb The Journal of biological chemistry 1977 new
The role of DNA polymerase I-associated 5'-exonuclease in replication of coliphage M13 replicative-form DNA. S Dasgupta, S Mitra Biochem Biophys Res Commun 1977 new
DNA synthetic activity of nuclei isolated from differentiating cardiac muscle and association of DNA polymerase alpha with the outer nuclear membrane. W C Claycomb Dev Biol 1977 new
Inhibitors of Bacillus subtilis DNA polymerase III. 6-(arylalkylamino)uracils and 6-anilinouracils. Neal C Brown, Joseph Gambino, George E Wright J Med Chem 1977 new
Effects of nuclear proteins on the activity of soybean DNA polymerase. V L Dunham, W N Yunghans Biochem Biophys Res Commun 1977 new
Primed and unprimed synthesis of poly (dA-dT) by calf thymus DNA polymerase alpha. D Henner, J J Further The Journal of biological chemistry 1977 new
Early effects of phytohemagglutinin on induction of DNA polymerase, thymidine kinase, deoxyribonucleoside triphosphate pools and DNA synthesis in human lymphocytes. G Tyrsted, B Munch-Petersen Nucleic acids research 1977 new
Synergistic and antagonistic effects of progesterone and oestrogen on oestrogen receptor concentration and DNA polymerase activity in chick oviduct. R L Sutherland, M C Lebeau, P H Schmelck, E E Baulieu FEBS letters 1977 new
Levels of DNA polymerase-alpha and beta in normal and xeroderma pigmentosum fibroblasts. U Bertazzoni, M Stefanini, G Pedrali-Noy, F Nuzzo, A Falaschi Nucleic acids research 1977 new
DNA polymerase from mesophilic and thermophilic bacteria. III. Lack of fidelity in the replication of synthetic polydeoxyribonucleotides by DNA polymerase from Bacillus licheniformis and Bacillus stearothermophilus. J Stenesh, G R McGowan Biochimica et biophysica acta 1977 partial results
Priming of deoxyribonucleic acid synthesis on phage fd and phiX174 templates by oligoribonucleotides contaminating nucleoside 5'-triphosphates. Y Masamune, Charles C Richardson The Journal of biological chemistry 1977 new
DNA-polymerase inhibitors. Rifamycin derivatives. L Y Frolova, Y A Meldrays, L L Kochkina, S A Giller, A V Eremeyev, N A Grayevskaya, L L Kisselev Nucleic acids research 1977 new
Interferon induction by polynucleotides: structure-function relationship. Erik De Clercq Texas reports on biology and medicine 1977 new
Inhibition of E. coli DNA polymerase I by 1,10-phenanthroline. V D'Aurora, A M Stern, D S Sigman Biochem Biophys Res Commun 1977 pols set
DNA sequencing with chain-terminating inhibitors. F Sanger, S Nicklen, A R Coulson Proceedings of the National Academy of Sciences of the United States of America 1977 pols set
Action of intercalating agents on the activity of DNA polymerase I. R Böhner, U Hagen Biochimica et biophysica acta 1977 new
The role of DNA polymerase I in liquid holding recovery of UV-irradiated Escherichia coli. M S Tang, M H Patrick Photochem Photobiol 1977 new
e antigen and antibody, DNA polymerase, and inhibitors of DNA polymerase in acute and chronic hepatitis. R Cappel, F DeCuyper, D Van Beers J Infect Dis 1977 new
Assembly of Bacillus subtilis phage phi29. 1. Mutants in the cistrons coding for the structural proteins. Ana Camacho, F Jiménez, J De La Torre, José L Carrascosa, R P Mellado, C Vásquez, E Viñuela, Margarita Salas Eur J Biochem 1977 pols set
The deoxyribonucleic acid polymerases of non-vertebrate eukaryotes. A G McLennan, H M Keir Biochemical Society symposium 1977 topics set
[DNA polymerases of animal cells: III. DNA replication and DNA polymerase alpha (author's transl)]. Akio Matsukage Tanpakushitsu Kakusan Koso 1977 new
HeLa cell DNA polymerases: the effect of cycloheximide in vivo and detection of a new form of DNA polymerase alpha. G P Noy, A Weissbach Biochimica et biophysica acta 1977 new
Persistence of RNA attached to nascent short DNA pieces in Bacillus subtilis cells defective in DNA polymerase I. F Tamanoi, T Okazaki, R Okazaki Biochem Biophys Res Commun 1977 new
DNA synthesized in the hepatitis B Dane particle DNA polymerase reaction. L I Lutwick, W S Robinson J Virol 1977 new
Enhancement of DNA polymerase II activity in E. coli after treatment with N-methyl-N'-nitro-N-nitrosoguanidine. M Miyaki, G E Sai, S Katagiri, N Akamatsu, T Ono Biochem Biophys Res Commun 1977 new
A particulation DNA polymerase activity in adult rat brain. S S Witkin, H M Schumaker Biochem Biophys Res Commun 1977 new
Replication of duplex DNA by bacteriophage T7 DNA polymerase and gene 4 protein is accompanied by hydrolysis of nucleoside 5'-triphosphates. R Kolodner, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 1977 pols set
Excision-repair in mutants of Escherichia coli deficient in DNA polymerase I and/or its associated 5' leads to 3' exonuclease. P Cooper Mol Gen Genet 1977 new
Varicella-zoster virus-induced DNA polymerase. R L Miller, F Rapp The Journal of general virology 1977 new
Mitochondrial DNA polymerase from rat liver. T Fujisawa, Shigeru Tanaka, M Kobayashi, K Koike Biochimica et biophysica acta 1977 new
Stimulation of sea urchin DNA polymerase by protein factors. II. Formation of active complex in DNA polymerase reaction. K Murakami-Murofushi, Y Mano Biochimica et biophysica acta 1977 new
Endogenous DNA polymerase activity in fractionated rat lever chromatin. J Y Chan, L W Rodriguez, F F Becker Nucleic acids research 1977 new
Mutator mutations in bacteriophage T4 gene 42 (dHMC hydroxymethylase). W E Williams, J W Drake Genetics 1977 complete
Mechanism of T5-induced DNA polymerase. II. Characterization of the dead-end complex. Somes K Das, R K Fujimura The Journal of biological chemistry 1977 new
Increased DNA polymerase and ATP-dependent deoxyribonuclease activities following DNA damages in mycobacterium smegmatis. A W MacNaughton, F G Winder Mol Gen Genet 1977 new
Discordant e antigen, DNA polymerase activity, and Dane particle responses in two patients representing an index case-contact case pair with hepatitis B virus infection. R P Perrillo, L D Gelb, W H Milligan, W Wellinghoff, R D Aach J Infect Dis 1977 new
Template specificity of rat mitochondrial DNA polymerase. Shigeru Tanaka, K Koike Biochimica et biophysica acta 1977 new
Purification and characterization of the DNA polymerase of human breast cancer particles. T Ohno, R W Sweet, D Dejak, S Spiegelman Proceedings of the National Academy of Sciences of the United States of America 1977 new
Nuclear DNA polymerase-alpha and replicative potential in mammalian cells. P G Braunschweiger, L M Schiffer Eur J Cancer 1977 new
Action of pancreatic DNase: requirements for activation of DNA as a template-primer for DNA polymerase. E Baril, J Mitchener, L Lee, B Baril Nucleic acids research 1977 new
Separation of DNA-dependent DNA polymerase activities in Micrococcus radiodurans. S Kitayama, A Matsuyama Biochimica et biophysica acta 1977 new
Studies on the biochemical basis of mutation. IV. Effect of amino acid substitution on the enzymatic and biological properties of bacteriophage T4 DNA polymerase. Linda J Reha-Krantz, M J Bessman Journal of molecular biology 1977 complete
Regulatory factors produced by lymphocytes. II. Inhibition of cellular DNA synthesis associated with a factor inhibiting DNA polymerase alpha activity. S C Lee, Z J Lucas J Immunol 1977 new
Effect of calcium on the recovery and distribution of DNA polymerase alpha from cultured human cells. D C Eichler, Paul A Fisher, D Korn The Journal of biological chemistry 1977 pols set
DNA polymerase III holoenzyme of Escherichia coli. Purification and resolution into subunits. C McHenry, Arthur Kornberg The Journal of biological chemistry 1977 partial results
DNA polymerase activity and antibody against it in sera of patients with systemic lupus erythematosus. C Altaner, L Cebecauer Biomedicine 1977 new
DNA polymerase of mitochondria is a gamma-polymerase. A Bolden, G P Noy, A Weissbach The Journal of biological chemistry 1977 topics set
2-Aminopurine-induced mutagenesis in T4 bacteriophage: a model relating mutation frequency to 2-aminopurine incorporation in DNA. Myron F Goodman, R Hopkins, W C Gore Proceedings of the National Academy of Sciences of the United States of America 1977 complete
Progesterone-induced DNA polymerase activity in full-grown oocytes of Xenopus laevis (1). P Grippo, G Locorotondo, C Taddei J Exp Zool 1977 pols set
In vivo functional interaction between DNA polymerase and dCMP-hydroxymethylase of bacteriophage T4. J Chao, M Leach, J Karam J Virol 1977 pols set
Effect of some aminoquinone compounds on nucleic acid synthesis catalyzed by E. coli DNA polymerase I and RNA polymerase. N Mochizuki, S Okada, O Tamemasa Chem Pharm Bull (Tokyo) 1977 pols set
Effect of neocarzinostatin-induced strand scission on the template activity of DNA for DNA polymerase I. L S Kappen, I H Goldberg Biochemistry 1977 new
DNA polymerase-beta from the nuclear fraction of sea urchin embryos: characterization of the purified enzyme. C Suzuki-Hori, H Nagano, Y Mano J Biochem 1977 new
Variation of DNA polymerases-alpha, -beta. and -gamma during perinatal tissue growth and differentiation. Ulrich Hübscher, C C Kuenzle, Silvio Spadari Nucleic acids research 1977 topics set
A single-strand-specific DNA-binding protein from mouse cells that stimulates DNA polymerase. B Otto, M Baynes, R Knippers Eur J Biochem 1977 pols set
In vitro replication of mitochondrial DNA. Elongation of the endogenous primer sequence in D loop mitochondrial DNA by human DNA polymerase beta. D C Eichler, Teresa S-F Wang, D A Clayton, D Korn The Journal of biological chemistry 1977 pols set
Identity of DNA polymerase gamma from synaptosomal mitochondria and rat-brain nuclei. Ulrich Hübscher, C C Kuenzle, Silvio Spadari European journal of biochemistry / FEBS 1977 topics set
Prophage induction in Escherichia coli K12 cells deficient in DNA polymerase I. M Blanco, L Pomes Mol Gen Genet 1977 new
Early diagnosis of Hepatitis B by Dane particle associated DNA polymerase assay. R Cappel, F De Cuyper, D Van Beers, M Toppet, S Cadranel The Journal of general virology 1977 new
Primer-mediated inhibition of the hydrolysis of template DNA by T5-induced DNA polymerase. Somes K Das Biochem Biophys Res Commun 1977 new
Structure of hepatitis B Dane particle DNA before and after the Dane particle DNA polymerase reaction. J F Hruska, D A Clayton, J L Rubenstein, W S Robinson J Virol 1977 new
DNA polymerases from bakers' yeast. L M Chang The Journal of biological chemistry 1977 topics set
Is DNA polymerase I necessary for most UV-induced mutation from tryptophan auxotrophy in Escherichia coli B/r WP2? C O Doudney Mutation research 1977 new
Inhibition of DNA polymerase-alpha and -beta of calf thymus by 1-beta-D-arabinofuranosylcytosine-5'-triphosphate. Shonen Yoshida, Masami Yamada, S Masaki Biochimica et biophysica acta 1977 new
DNA polymerases in adenovirus type 5-infected and uninfected KB cells. Induction of an alpha-type DNA polymerase in adenovirus type 5-infected and in fast growing cells. A de Jong, Peter C van der Vliet, H S Jansz Biochimica et biophysica acta 1977 new
Ionic requirements of the DNA polymerase associated with serum hepatitis B antigen. S Z Hirschman, E Garfinkel J Infect Dis 1977 new
Bacillus subtilis DNA polymerase III is required for the replication of DNA of bacteriophages SPP-1 and phi 105. S D Rowley, Neal C Brown J Virol 1977 new
Screening for deficits in DNA repair by the response of irradiated human lymphocytes to phytohemagglutinin. S S Agarwal, D Q Brown, E J Katz, Lawrence A Loeb Cancer research 1977 new
Ozone-induced DNA degradation in different DNA polymerase I mutants of Escherichia coli K12. C Hamelin, F Sarhan, Y S Chung Biochem Biophys Res Commun 1977 pols set
Recent excitement in the DNA replication problem. B Alberts, R Sternglanz Nature 1977 pols set
Nonstructural proteins of herpes simplex virus. I. Purification of the induced DNA polymerase. K L Powell, D J Purifoy J Virol 1977 new
Measurement and specificity of serum dna polymerase. E S Carter, J R Wands, E Alpert, K J Isselbacher N Engl J Med 1977 new
Effects of streptovaricins and their degradation products on RNA-directed DNA polymerase of Rauscher leukemia virus. L H Li, C H Cowie, L G Gray, D M Moran, T D Clark, K L Rinehart J Natl Cancer Inst 1977 new
Identification of the herpes simplex virus DNA polymerase gene. D J Purifoy, R B Lewis, K L Powell Nature 1977 new
A DNA polymerase from Ustilago maydis. Evidence of proof-reading by the associated 3' leads to 5' deoxyribonuclease activity. G T Yarranton, G R Banks Eur J Biochem 1977 new
Mechanism of T5-induced DNA polymerase. I. Replication of short primer templates. Somes K Das, R K Fujimura The Journal of biological chemistry 1977 new
Cell-free synthesis of the precursor polypeptide for avian myeloblastosis virus DNA polymerase. B M Paterson, D J Marciani, T S Papas Proceedings of the National Academy of Sciences of the United States of America 1977 new
Inhibition of DNA polymerase from L1210 murine leukemia by a sulfhydryl reagent from agaricus bisporus. D G Graham, R W Tye, F S Vogel Cancer research 1977 new
Biologic activities of poly (2-azaadenylic acid) and poly (2-azainosinic acid). Erik De Clercq, G F Huang, P F Torrence, T Fukui, N Kakiuchi, M Ikehara Nucleic acids research 1977 new
DNA polymerase-alpha. Purification and structural characterization of the near homogeneous enzyme from human KB cells. Paul A Fisher, D Korn The Journal of biological chemistry 1977 pols set
Characterization of a DNA polymerase associated with an endogenous DNA-synthesizing complex isolated from human lymphoid cells. Shonen Yoshida, L F Cavalieri Biochimica et biophysica acta 1977 new
Chick-embryo DNA polymerase gamma. Identity of gamma-polymerases purified from nuclei and mitochondria. U Bertazzoni, A I Scovassi, G M Brun European journal of biochemistry / FEBS 1977 topics set
Herpes simplex virus DNA polymerase as the site of phosphonoacetate sensitivity: temperature-sensitive mutants. D J Purifoy, K L Powell J Virol 1977 new
Effect of ribonucleotides on substrate availability for DNA polymerase assays in cytoplasmic fractions of rat intestinal mucosa. S H Zbarsky, S Chevalier Can J Biochem 1977 new
Purification and characterization of baboon endogenous virus DNA polymerase. P S Sarin, B Friedman, R C Gallo Biochimica et biophysica acta 1977 new
Nuclear localisation of DNA polymerase alpha and DNA synthesis in polyoma virus infected mouse cells. U Wintersberger, E Wintersberger Oncology 1977 new
Purification and properties of Rauscher leukemia virus DNA polymerase and selective inhibition of mammalian viral reverse transcriptase by inorganic phosphate. Mukund J Modak, S L Marcus The Journal of biological chemistry 1977 new
Biochemical characterization of mutant forms of DNA polymerase I from Escherichia coli. I. The polA12 mutation. D Uyemura, I. Robert Lehman The Journal of biological chemistry 1976 pols set
Studies on DNA alpha-polymerase of mouse myeloma: partial purification and comparison of three molecular forms of the enzyme. Akio Matsukage, M Sivarajan, Samuel H Wilson Biochemistry 1976 new
Distinguishing cytomegalovirus, mycoplasma, and cellular DNA polymerases. R L Miller, F Rapp J Virol 1976 topics set
Particulate DNA polymerase from the cytoplasm of Xenopus laevis oocytes. M I Baldi, P Bazzicalupo, G P Tocchini-Valentini Biochem Biophys Res Commun 1976 pols set
Multiple forms of rat liver mitochondrial DNA polymerase. L J Klunk, G F Kalf Arch Biochem Biophys 1976 new
Ehrlich ascites tumor (EAT) chalone effects on nascent DNA synthesis and DNA polymerase alpha and beta. G S Nakai Cell Tissue Kinet 1976 new
Differential response of type C and intracisternal type A particle markers in cells treated with iododeoxyuridine and dexamethasone. E L Kuff, K K Lueders, J M Orenstein, Samuel H Wilson Journal of virology 1976 new
Fluctuation in activity of the molecular forms of cellular DNA polymerase during infection by SV40. L H Lazarus, N Kitron Arch Virol 1976 new
Effect of a single treatment with the alkylating carcinogens dimethylnitrosamine and methyl methanesulphonate on liver regenerating after partial hepatectomy. III. Effect on DNA synthesis in vivo and on DNA polymerase activity assayed in vitro. V M Craddock Chem Biol Interact 1976 new
Studies on the molecular species of DNA polymerase extracted from rat ascites hepatoma cells. K Tanabe, Tomonori Takahashi Journal of biochemistry 1976 new
Involvement of escherichia coli dnaZ gene product in DNA elongation in vitro. S Wickner, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1976 new
Initiation of replication in chromosomal DNA induced by extracts from proliferating cells. S M Jazwinski, J L Wang, G M Edelman Proceedings of the National Academy of Sciences of the United States of America 1976 new
Inhibition of cellular DNA synthesis in hamster kidney cells infected with western equine encephalitis virus. B Simizu, M Wagatsuma, A Oya, Fumio Hanaoka, Masami Yamada Archives of virology 1976 new
Physical map of bacteriophage phi29 DNA. M R Inciarte, José María Lázaro, Margarita Salas, E Vińuela Virology 1976 pols set
Purification and properties of murine mammary tumor virus DNA polymerase. S L Marcus, N H Sarkar, Mukund J Modak Virology 1976 new
Poly rC-oligo dG specific template activity of mouse viral DNA polymerase detected by isoelectric focusing. P G Ingalls, J C Bartholomew, E L Bennett Biochem Biophys Res Commun 1976 new
Template recognition and chain elongation in DNA synthesis in vitro. E C Travaglini, D K Dube, S Surrey, Lawrence A Loeb Journal of molecular biology 1976 new
polA6, A mutation affecting the DNA binding capacity of DNA polymerase I. W S Kelly, Nigel D F Grindley Nucleic acids research 1976 new
Terminal labeling and addition of homopolymer tracts to duplex DNA fragments by terminal deoxynucleotidyl transferase. R Roychoudhury, E Jay, R Wu Nucleic acids research 1976 partial results
Observations on template-specific conditions for DNA synthesis by avian myeloblastosis virus DNA polymerase. S L Marcus, Mukund J Modak Nucleic acids research 1976 new
Heat mutagenesis in bacteriophage T4: the transversion pathway. P M Bingham, R H Baltz, L S Ripley, John W Drake Proceedings of the National Academy of Sciences of the United States of America 1976 complete
Escherichia coli thioredoxin: a subunit of bacteriophage T7 DNA polymerase. D F Mark, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 1976 pols set
Vitamin B12--folate interrelations. K C Das, V Herbert Clinics in haematology 1976 new
On the processive mechanism of Escherichia coli DNA polymerase I. Delayed initiation of polymerization. Robert A Bambara, D Uyemura, I. Robert Lehman The Journal of biological chemistry 1976 pols set
A simplified procedure for the analysis of DNA polymerase III levels in Bacillus subtilis strains. G Ciarrocchi, A Fortunato, C Attolini, A Falaschi Nucleic acids research 1976 new
[Detailed model of semi-conservative DNA replication. Possible role of DNA-polymerase errors in fragmented copying of both matrix strands]. M I Mosevitskiĭ Genetika 1976 new
Further characterization of a DNA polymerase activity in mouse sperm nuclei. Magali Philippe, P Chevaillier Biochimica et biophysica acta 1976 new
Exonuclease associated with bacteriophage T5-Induced DNA polymerase. Somes K Das, R K Fujimura Journal of virology 1976 partial results
[DNA repair, change in DNA-polymerase and DNA-ligase activity of regenerating liver in gamma-irradiated rats]. D T Zakrzhevskaia, N N Vtiurin, A I Gaziev Radiobiologiia 1976 new
Biochemical characterization of mutant forms of DNA polymerase I from Escherichia coli. II. The polAex1 mutation. D Uyemura, D C Eichler, I. Robert Lehman The Journal of biological chemistry 1976 pols set
Deoxyribonucleic acid polymerase from the extreme thermophile Thermus aquaticus. A Chien, D B Edgar, J M Trela J Bacteriol 1976 topics set
Action of partially thiolated polynucleotides on the DNA polymerase alpha from regenerating rat liver. M P Kung, Y K Ho, T J Bardos Cancer research 1976 new
Characterization of DNA polymerase associated with nuclear membrane fractions from uninfected and adenovirus 2-infected KB cells. K Ito, M Arens, M Green Biochimica et biophysica acta 1976 new
Control of mutation frequency by bacteriophage T4 DNA polymerase. II. Accuracy of nucleotide selection by the L88 mutator, CB120 antimutator, and wild type phage T4 DNA polymerases. F D Gillin, Nancy G Nossal The Journal of biological chemistry 1976 pols set
An antimutator deoxyribonucleic acid polymerase. II. In vitro and in vivo studies of its temperature sensitivity. K Y Lo, M J Bessman The Journal of biological chemistry 1976 complete
Nuclear location of mammalian DNA polymerase activities. D N Foster, T Gurney The Journal of biological chemistry 1976 pols set
Structure and assembly of phage phi29. E Viñuela, Ana Camacho, F Jiménez, José L Carrascosa, G Ramírez, Margarita Salas Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1976 pols set
DNA polymerase I: essential replication enzyme. I. Robert Lehman, D G Uyemura Science 1976 new
Metal-induced infidelity during DNA synthesis. M A Sirover, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1976 new
On the fidelity of DNA replication. Lack of exodeoxyribonuclease activity and error-correcting function in avian myeloblastosis virus DNA polymerase. N Battula, Lawrence A Loeb The Journal of biological chemistry 1976 partial results
Control of mutation frequency by bacteriophage T4 DNA polymerase. I. The CB120 antimutator DNA polymerase is defective in strand displacement. F D Gillin, Nancy G Nossal The Journal of biological chemistry 1976 pols set
Mutator mutations in bacteriophage T4 gene 32 (DNA unwinding protein). R E Koch, M K McGaw, John W Drake J Virol 1976 complete
On the association of reverse transcriptase with polynucleotide templates during catalysis. D K Dube, Lawrence A Loeb Biochemistry 1976 new
Bacillus subtilis phage phi29. Characterization of gene products and functions. José L Carrascosa, Ana Camacho, F Moreno, F Jiménez, R P Mellado, E Viñuela, Margarita Salas Eur J Biochem 1976 pols set
Induction of mutations in B. subtilis phage SPP1 by growth on host cells carrying a mutator DNA polymerase III. M A Montenegro, H Esche, T A Trautner Mol Gen Genet 1976 new
[Separation of the enzyme catalyzing polymerization of deoxyribonucleoside diphosphates from preparations of E. coli DNA-polymerase I]. I A Nazarenko, T A Beliaeva, N V Vorobbeva, I F Nekhanevich, V A Potapov Mol Biol (Mosk) 1976 pols set
Replication of bacteriophage M13. X. M13 replication in a mutant of Escherichia coli defective in the 5' leads to 3' exonuclease associated with DNA polymerase I. T C Chen, D S Ray Journal of molecular biology 1976 new
On the fidelity of DNA replication. Enzyme activities associated with DNA polymerases from RNA tumor viruses. G Seal, Lawrence A Loeb The Journal of biological chemistry 1976 new
Restriction of carcinogen-induced error incorporation during in vitro DNA synthesis. M A Sirover, Lawrence A Loeb Cancer research 1976 new
UV mutagenesis in radiation-sensitive strains of yeast. C W Lawrence, R Christensen Genetics 1976 topics set
RNA-dependent DNA polymerase activity of RNA tumor virus. VI. Processive mode of action of avian myeloblastosis virus polymerase. J P Leis Journal of virology 1976 partial results
Mutants of Pseudomonas aeruginosa deficient in DNA polymerase I. P R Lehrbach, A H Kung, B T Lee Mutation research 1976 topics set
Impaired estrogen-mediated production of type C viral DNA polymerase in aged NH swiss mouse uteri. J E Strickland, G A Saviolakis, A K Fowler, N M Kouttab, A Hellman Proc Soc Exp Biol Med 1976 new
An antimutator deoxyribonucleic acid polymerase. I. Purification and properties of the enzyme. K Y Lo, M J Bessman The Journal of biological chemistry 1976 complete
Intracellular localization of mouse DNA polymerase-alpha. G Herrick, B B Spear, G Veomett Proceedings of the National Academy of Sciences of the United States of America 1976 topics set
HeLa cell DNA polymerase gamma: further purification and properties of the enzyme. K W Knopf, Masami Yamada, A Weissbach Biochemistry 1976 new
A cytoplasmic inhibitor of DNA polymerase from the plasmodia of Physarum polycephalum. K Murakami-Murofushi, H Nagano, Y Mano J Biochem 1976 new
Temperature-sensitive DNA polymerase induced by a bacteriophage T5 mutant: relationship between polymerase and exonuclease activities. R K Fujimura, B C Roop Biochemistry 1976 new
Chloramphenicol-induced loss of mitochondrial DNA polymerase activity in HeLa cells. K Radsak, A Weissbach Hoppe Seylers Z Physiol Chem 1976 new
Novikoff hepatoma deoxyribonucleic acid polymerase. Sensitivity of the beta-polymerase to sulfhydryl blocking agents. D W Mosbaugh, Thomas A Kunkel, D M Stalker, J E Tcheng, R R Meyer Nucleic acids research 1976 topics set
High molecular weight deoxyribonucleic acid polymerase from crown gall tumor cells of periwinkle (Vinca rosea). J M Gardner, C I Kado Biochemistry 1976 topics set
A new mammalian DNA polymerase with 3' to 5' exonuclease activity: DNA polymerase delta. J J Byrnes, Kathleen M Downey, V L Black, Antero G So Biochemistry 1976 topics set
Novikoff hepatoma deoxyribonucleic acid polymerase. Purification and properties of a homogeneous beta polymerase. D M Stalker, D W Mosbaugh, R R Meyer Biochemistry 1976 new
Role of purine N-3 in the biologic activities of poly(A) and poly(I). Erik De Clercq, P F Torrence, T Fukui, M Ikehara Nucleic acids research 1976 new
Evaluation of a DNA polymerase-deficient mutant of E. coli for the rapid detection of carcinogens. E R Fluck, L A Poirier, H W Ruelius Chem Biol Interact 1976 pols set
Variations of DNA polymerase-alpha and -beta during prolonged stimulation of human lymphocytes. U Bertazzoni, M Stefanini, G P Noy, E Giulotto, F Nuzzo, A Falaschi, Silvio Spadari Proceedings of the National Academy of Sciences of the United States of America 1976 topics set
On the measurement of tritium in DNA and its applications to the assay of DNA polymerase activity. B K Schrier, Samuel H Wilson Methods in cell biology 1976 new
Transcription in vitro of phi29 DNA and EcoRI fragments by Bacillus subtilis RNA polymerase. M R Inciarte, E Viñuela, Margarita Salas Eur J Biochem 1976 pols set
Mechanism of DNA elongation catalyzed by Escherichia coli DNA polymerase III, dnaZ protein, and DNA elongation factors I and III. S Wickner Proceedings of the National Academy of Sciences of the United States of America 1976 pols set
Template specific inhibitor of mammalian DNA polymerases. J Pitha, Samuel H Wilson Nucleic acids research 1976 new
Phylogeny of DNA polymerase-beta. L M Chang Science (New York, N.Y.) 1976 topics set
On the processive mechanism of Escherichia coli DNA polymerase I. D Uyemura, R Bambara, I. Robert Lehman The Journal of biological chemistry 1975 pols set
Bacteriophage T7 deoxyribonucleic acid replication invitro. Bacteriophage T7 DNA polymerase: an an emzyme composed of phage- and host-specific subunits. P Modrich, Charles C Richardson The Journal of biological chemistry 1975 partial results
Transversion mutagenesis in bacteriophage T4. L S Ripley Mol Gen Genet 1975 complete
Energy-dependent activation of the temperature-sensitive DNA polymerases induced by bacteriophage T4 gene 43 mutants. J Thorner, W M Huang, I. Robert Lehman Virology 1975 new
Endogenous DNA polymerase-positive core particles from hepatitis-infected hepatocytes. H A Fields, G R Dreesman, F B Hollinger, F Marciano-Cabral, F Gyorkey, J L Melnick Intervirology 1975 new
Bacteriophage T7 Deoxyribonucleic acid replication in vitro. A protein of Escherichia coli required for bacteriophage T7 DNA polymerase activity. P Modrich, Charles C Richardson The Journal of biological chemistry 1975 partial results
A sensitive test for antibody against the hepatitis B core antigen (anti-HB-c). R L Greeman, W S Robinson, G N Vyas Vox sanguinis 1975 topics set
Immunological relationships between chick embryo polymerases. G M Brun, L M Assairi, F Chapeville The Journal of biological chemistry 1975 topics set
T4 DNA polymerase has a lower apparent Km for deoxynucleoside triphosphates complementary rather than noncomplementary to the template. F D Gillin, Nancy G Nossal Biochem Biophys Res Commun 1975 complete
Conformation of deoxynucleoside triphosphate substrates on DNA polymerase I from Escherichia coli as determined by nuclear magnetic relaxation. D L Sloan, Lawrence A Loeb, A S Mildvan The Journal of biological chemistry 1975 pols set
Alterations of DNA-dependent DNA polymerase activities in the immature quail oviduct in response to estrogen stimulation. H J Rohde, W E Müller, R K Zahn Nucleic acids research 1975 new
The steady state kinetic parameters and non-processivity of Escherichia coli deoxyribonucleic acid polymerase I. W R McClure, T M Jovin The Journal of biological chemistry 1975 partial results
New properties of the DNA polymerase-beta isolated from non stimulated normal human lymphocytes. M T Franze de Fernandez, J Mordoh, B R Fridlender Biochem Biophys Res Commun 1975 new
Bacteriophage T7 deoxyribonucleic acid replication in vitro. Purification and properties of the gene 4 protein of bacteriophage T7. David C Hinkle, Charles C Richardson The Journal of biological chemistry 1975 pols set
On the DNA polymerase III of mouse myeloma: partial purification and characterization. Akio Matsukage, E W Bohn, Samuel H Wilson Biochemistry 1975 new
Studies on a DNA polymerse gamma-like enzyme from wheat embryos. L Tarragó-Litvak, Michel Castroviejo, Simon Litvak FEBS letters 1975 topics set
Reconstruction of bacteriophage T4 DNA replication apparatus from purified components: rolling circle replication following de novo chain initiation on a single-stranded circular DNA template. C F Morris, N K Sinha, B M Alberts Proceedings of the National Academy of Sciences of the United States of America 1975 complete
Properties of the DNA polymerase induced by Marek's disease herpesvirus, strain GA, upon infection of duck embryo fibroblasts. J A Boezi, L F Lee, H C Towle, R W Blakesley, B R Burmester IARC Sci Publ 1975 new
Deoxyribonucleic acid polymerase III of Escherichia coli. Purification and properties. D M Livingston, David C Hinkle, Charles C Richardson The Journal of biological chemistry 1975 pols set
Synthesis in vitro of phi29-specific early proteins directed by phage DNA. José L Carrascosa, F Jiménez, E Viñuela, Margarita Salas Eur J Biochem 1975 pols set
Comparison of DNA polymerase activities induced by herpes simplex virus types 1 and 2. D J Purifoy Intervirology 1975 new
Two temperature-sensitive polA mutants: an approach to the role in vivo of DNA polymerase I. D G Uyemura, EB Konrad, I. Robert Lehman Basic life sciences 1975 new
On the fidelity of DNA replication. Characterization of polynucleotides with errors in base-pairing synthesized by avian myeloblastosis virus deoxyribonucleic acid polymerase. N Battula, Lawrence A Loeb The Journal of biological chemistry 1975 new
RNA-dependent DNA polymerase activity of RNA tumor viruses. V. Rous sarcoma virus single-stranded RNA-DNA covalent hybrids in infected chicken embryo fibroblast cells. J Leis, A Schincariol, R Ishizaki, Jerard Hurwitz Journal of virology 1975 new
Differential sensitivity of low molecular weight DNA polymerase to sulfhydryl-blocking reagents. Akio Matsukage, E W Bohn, Samuel H Wilson Biochimica et biophysica acta 1975 new
Inhibition of oncornavirus functions by 2'-azido polynucleotides. Erik De Clercq, A Billiau, J Hobbs, P F Torrence, B Witkop Proceedings of the National Academy of Sciences of the United States of America 1975 new
Nuclear DNA polymerases and the HeLa cell cycle. R W Chiu, E F Baril The Journal of biological chemistry 1975 topics set
Nomenclature of eukaryotic DNA polymerases. A Weissbach, D Baltimore, F Bollum, R Gallo, D Korn Science (New York, N.Y.) 1975 topics set
Incorporation of the purine moieties of guanosine and inosine analogs into nucleotide pools of human erythrocytes. C M Kong, R E Parks Biochem Pharmacol 1975 topics set
Avian myeloblastosis virus DNA polymerase. Kinetic studies on the incorporation of noncomplementary nucleotides. N Battula, D Dube, Lawrence A Loeb The Journal of biological chemistry 1975 new
RNA-primed DNA synthesis: specific catalysis by HeLa cell DNA polymerase alpha. Silvio Spadari, A Weissbach Proceedings of the National Academy of Sciences of the United States of America 1975 topics set
DNA-metabolizing enzymes in normal human lymphoid cells. VI. Induction of DNA polymerases alpha, beta, and gamma following stimulation with phytohemagglutinin. R J Mayer, R G Smith, R C Gallo Blood 1975 topics set
Association of phiX174 DNA-dependent ATPase activity with an Escherichia coli protein, replication factor Y, required for in vitro synthesis of phiX174 DNA. S Wickner, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1975 new
Inhibition of oncornavirus functions by poly (2-methylthioinosinic acid). Erik De Clercq, A Billiau, M Hattori, M Ikehara Nucleic acids research 1975 new
Hbc ag, anti-HBC, and DNA polymerase activity in transfused recipients followed prospectively. F B Hollinger, G R Dressman, H Fields, J Melnick Am J Med Sci 1975 new
T4 DNA polymerase (gene 43) is required in vivo for repair of gaps in recombinants. R C Miller J Virol 1975 complete
Serological analysis of human deoxyribonucleic acid polymerases. Preparation and properties of antiserum to deoxyribonucleic acid polymerase I from human lymphoid cells. R G Smith, J W Abrell, B J Lewis, R C Gallo The Journal of biological chemistry 1975 topics set
Studies on reverse transcriptase of RNA tumor viruses III. Properties of purified Moloney murine leukemia virus DNA polymerase and associated RNase H. I M Verma J Virol 1975 partial results
De Novo Biosynthesis of Deoxyribonucleic Acid Polymerase during Wheat Embryo Germination. Y Y Mory, D Chen, S Sarid Plant physiology 1975 topics set
Inhibition of RNA-dependent DNA polymerase of murine oncornaviruses by ammonium-5-tungsto-2-antimoniate. J C Chermann, F C Sinoussi, C Jasmin Biochem Biophys Res Commun 1975 new
Kinetic analysis of Escherichia coli deoxyribonucleic acid polymerase I. E C Travaglini, A S Mildvan, Lawrence A Loeb The Journal of biological chemistry 1975 partial results
Partial purification and characterization of two cytoplasmic DNA polymerases from ungerminated wheat. Michel Castroviejo, L Tarragó-Litvak, Simon Litvak Nucleic acids research 1975 topics set
Purification and characterization of the DNA polymerase and RNase H activities in Moloney murine sarcoma-leukemia virus. G F Gerard, D P Grandgenett J Virol 1975 partial results
Isolation and purification of mediators of cell proliferation. Thomas A Kunkel, R R Meyer, J W Alexander Archives of surgery (Chicago, Ill. : 1960) 1975 new
Deoxyribonucleic acid polymerase III of Escherichia coli. Characterization of associated exonuclease activities. D M Livingston, Charles C Richardson The Journal of biological chemistry 1975 pols set
Discrepancy in the mobility of a protein of phage phi29 in 2 different SDS polyacrylamide-gel systems. Ana Camacho, José L Carrascosa, E Vinuela, Margarita Salas Anal Biochem 1975 pols set
Absence of a low-molecular-weight DNA polymerase from nuclei of the yeast, Saccharomyces cerevisiae. U Wintersberger European journal of biochemistry / FEBS 1974 topics set
The N-terminal amino-acid sequences of DNA polymerase I from Escherichia coli and of the large and the small fragments obtained by a limited proteolysis. H Jacobsen, H Klenow, K Overgaard-Hansen Eur J Biochem 1974 pols set
Studies on the biochemical basis of spontaneous mutation. III. Rate model for DNA polymerase-effected nucleotide misincorporation. Myron F Goodman, W C Gore, N Muzyczka, M J Bessman Journal of molecular biology 1974 complete
Initiation of the transcription of phi29 DNA by Bacillus subtilis RNA polymerase. F Jiménez, J Avila, E Viñuela, Margarita Salas Biochimica et biophysica acta 1974 pols set
The interrelation between DNA synthesis and various DNA polymerase activities in synchronized HeLa cells. Silvio Spadari, A Weissbach Journal of molecular biology 1974 topics set
Involvement of two protein factors and ATP in in vitro DNA synthesis catalyzed by DNA polymerase 3 of Escherichia coli. Jerard Hurwitz, S Wickner Proceedings of the National Academy of Sciences of the United States of America 1974 pols set
Conversion of phiX174 viral DNA to double-stranded form by purified Escherichia coli proteins. S Wickner, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1974 new
Proceedings: Inhibition of mouse leukemia virus RNA-dependent DNA polymerase by 2'-OH-substituted polynucleotides. Erik De Clercq, A Billiau, J Hobbs, P F Torrence, B Witkop Hoppe-Seyler's Zeitschrift für physiologische Chemie 1974 new
HeLa cell R-deoxyribonucleic acid polymerases. Separation and characterization of two enzymatic activities. Silvio Spadari, A Weissbach The Journal of biological chemistry 1974 topics set
Isolation of a specialized transducing bacteriophage lambda carrying the polC locus of Escherichia coli. H Shizuya, D M Livingston, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 1974 new
DNA synthesis on a double-stranded DNA template by the T4 bacteriophage DNA polymerase and the T4 gene 32 DNA unwinding protein. Nancy G Nossal The Journal of biological chemistry 1974 complete
The infidelity of avian myeloblastosis virus deoxyribonucleic acid polymerase in polynucleotide replication. N Battula, Lawrence A Loeb The Journal of biological chemistry 1974 new
A comparative study of the effect of normal substrates and 5-iodo-2'-deoxyuridine triphosphate, a metabolic analog of thymidine triphosphate, on the inactivation of Escherichia coli deoxyribonucleic acid polymerase I and II by ultraviolet irradiation. K Y Ku, W H Prusoff The Journal of biological chemistry 1974 topics set
Zinc in reverse transcriptase. B J Poiesz, N Battula, Lawrence A Loeb Biochemical and biophysical research communications 1974 new
RNA-dependent DNA polymerase from avian myeloblastosis virus. J Leis, Jerard Hurwitz Methods in enzymology 1974 new
Adriamycin and daunorubicin inhibition of mutant T4 DNA polymerases. Myron F Goodman, M J Bessman, N R Bachur Proceedings of the National Academy of Sciences of the United States of America 1974 complete
Mutation to overproduction of bacteriophage T4 gene products. J D Karam, M G Bowles J Virol 1974 complete
Oncornavirus expression in human x mouse hybrid cells segregating mouse chromosomes. John D Minna, Adi F Gazdar, G M Iverson, T H Marshall, K STORMBERG, Samuel H Wilson Proceedings of the National Academy of Sciences of the United States of America 1974 new
Studies on the biochemical basis of spontaneous mutation. II. The incorporation of a base and its analogue into DNA by wild-type, mutator and antimutator DNA polymerases. M J Bessman, N Muzyczka, Myron F Goodman, R L Schnaar Journal of molecular biology 1974 topics set
Evidence for allosterism in in vitro DNA synthesis on RNA templates. L F Cavalieri, Mukund J Modak, S L Marcus Proceedings of the National Academy of Sciences of the United States of America 1974 pols set
Nucleotide sequence analysis of deoxyribonucleic acid. XIV. Conditions for the incorporation of ribonucleotides and deoxyribonucleotides into single-stranded areas of long double-stranded deoxyribonucleic acids. R T Hamilton, R Wu The Journal of biological chemistry 1974 topics set
Properties of a Bacillus subtilis strain lacking DNA polymerase I. Giuseppe Villani, U Canosi, A Fortunato, G Mazza, M Polsinelli, A Falaschi Nucleic acids research 1974 new
Replication of Escherichia coli requires DNA polymerase I. R M Olivera, E Bonhoeffer Nature 1974 new
DNA synthesis in strains of Escherichia coli K12 with temperature-sensitive DNA ligase and DNA polymerase I. EB Konrad, P Modrich, I. Robert Lehman Journal of molecular biology 1974 new
Influence of template inactivators on the binding of DNA polymerase to DNA. W E Müller, J Obermeier, A Totsuka, R K Zahn Nucleic acids research 1974 pols set
Purification of avian myeloblastosis virus DNA polymerase by affinity chromatography on polycytidylate-agarose. S L Marcus, Mukund J Modak, L F Cavalieri Journal of virology 1974 new
Ribonucleic acid dependent deoxyribonucleic acid synthesis by Escherichia coli deoxyribonucleic acid polymerase. I. Characterization of the polymerization reaction. E C Travaglini, Lawrence A Loeb Biochemistry 1974 new
A conditional lethal mutant of Escherichia coli K12 defective in the 5' leads to 3' exonuclease associated with DNA polymerase I. EB Konrad, I. Robert Lehman Proceedings of the National Academy of Sciences of the United States of America 1974 new
A 7S DNA polymerase in the cytoplasmic fraction from higher plant. B I Sahai Srivastava, J T Grace Life sciences 1974 topics set
Biophysical properties of bacteriophage phi29. V Rubio, Margarita Salas, E Viñuela, P Usobiaga, J L Saiz, J F Llopis Virology 1974 pols set
The incorporation of wrong bases by DNA polymerase I following gamma-irradiation of DNA-like templates. R Saffhill Biochimica et biophysica acta 1974 pols set
Reverse transcriptase: correlation of zinc content with activity. B J Poiesz, G Seal, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1974 new
The dissimilitude of the low and high molecular weight deoxyribonucleic acid-dependent deoxyribonucleic acid polymerases of HeLa cells. Silvio Spadari, R Muller, A Weissbach The Journal of biological chemistry 1974 topics set
Stimulation of DNA polymerase activity by the combination of p-hydroxymercuribenzoate and dithiothreitol. E W Bohn, Akio Matsukage, Samuel H Wilson Biochemical and biophysical research communications 1974 new
The effect of bisulfite modification on the template activity of DNA for DNA polymerase I. K Kai, T Tsuruo, H Hayatsu Nucleic acids research 1974 new
Excision of thymine dimers by proteolytic and amber fragments of E. coli DNA polymerase I. Errol C Friedberg, I. Robert Lehman Biochem Biophys Res Commun 1974 pols set
A holoenzyme form of deoxyribonucleic acid polymerase III. Isolation and properties. W Wickner, Arthur Kornberg The Journal of biological chemistry 1974 complete Joshua Mazzola
Deoxyribonucleic acid of Cancer pagurus. II. Template activity for a DNA-dependent DNA polymerase of eukaryotic cells. A M de Recondo, D Londos-Gagliardi, G Aubel-Sadron Nucleic acids research 1974 new
Multiple forms of DNA polymerase in mouse myeloma. Akio Matsukage, E W Bohn, Samuel H Wilson Proceedings of the National Academy of Sciences of the United States of America 1974 new
T4 DNA polymerase. I. Robert Lehman Methods in enzymology 1974 pols set
Studies on the activity of the A particle-associated Dna polymerase. E W Bohn, Samuel H Wilson Cancer research 1974 new
Sea urchin nuclear DNA polymerase. B S Fansler, Lawrence A Loeb Methods in enzymology 1974 new
DNA polymerase in the core of the human hepatitis B virus candidate. W S Robinson, R L Greenman Journal of virology 1974 topics set
Structural studies of avian myeloblastosis virus. Selective release of ribonucleoprotein polypeptides from the core component and partial purification of the DNA polymerase. K Stromberg, Samuel H Wilson Biochimica et biophysica acta 1974 new
DNA of a human hepatitis B virus candidate. W S Robinson, D A Clayton, R L Greenman Journal of virology 1974 topics set
Is bacteriophage T4 DNA polymerase involved in the repair of ultraviolet damage? C F Schnitzlein, I Albrecht, John W Drake Virology 1974 complete
Protection of avian myeloblastosis virus (AMV) DNA polymerase by substrates against heat inactivation. T S Papas, M A Chirigos, J G Chirikjian Nucleic acids research 1974 new
Proteins induced in Bacillus subtilis infected with bacteriophage phi29. José L Carrascosa, E Viñuela, Margarita Salas Virology 1973 pols set
Induction of DNA polymerase in mouse L cells. L M Chang, M Brown, F J Bollum Journal of molecular biology 1973 topics set
Thymineless mutagenesis in bacteriophage T4. M D Smith, R R Green, L S Ripley, John W Drake Genetics 1973 new
The identification of prereplicative bacteriophage T4 proteins. P Z O'Farrell, L Gold, W M Huang The Journal of biological chemistry 1973 topics set
Bacteriophage T4 gene expression. Evidence for two classes of prereplicative cistrons. P Z O'Farrell, L Gold The Journal of biological chemistry 1973 topics set
The genetic control of spontaneous and induced mutation rates in bacteriophage T4. John W Drake Genetics 1973 new
Construction of biologically functional bacterial plasmids in vitro. S N Cohen, A C Chang, H W Boyer, R B Helling Proceedings of the National Academy of Sciences of the United States of America 1973 topics set
Mutagenic DNA polymerase in human leukemic cells. C F Springgate, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 1973 new
DNA polymerase activity in human serum: studies with Australia Antigen. Lawrence A Loeb, R O Williams, A I Sutnick, A O'Connell, I Millman Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1973 new
Incorporation of purine analogs into the nucleotide pools of human erythrocytes. R E Parks, P R Brown, C M Kong Adv Exp Med Biol 1973 topics set
DNA polymerases I and II in regenerating rat liver and Morris hepatomas. E F Baril, M D Jenkins, O E Brown, J Laszlo, H P Morris Cancer research 1973 topics set
Mechanism of action of ribonuclease H isolated from avian myeloblastosis virus and Escherichia coli. J P Leis, I Berkower, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1973 new
Utilization of aminopurine deoxynucleoside triphosphate by mutator, antimutator and wild-type DNA polymerases of bacteriophage T4. R L Schnaar, N Muzyczka, M J Bessman Genetics 1973 complete
Copying natural RNAs with E. coli DNA polymerase I. Lawrence A Loeb, K D Tartof, E C Travaglini Nat New Biol 1973 pols set
A DNA-binding protein induced by bacteriophage T7. R C Reuben, M L Gefter Proceedings of the National Academy of Sciences of the United States of America 1973 new
Suppression of amber mutations of bacteriophage T4 gene 43 (DNA polymerase) by translational ambiguity. Jim D Karam, P V O'Donnell J Virol 1973 complete
Incorporation of nucleosides into the nucleotide pools of human erythrocytes. Adenosine and its analogs. R E Parks, P R Brown Biochemistry 1973 topics set
In vitro characterization of a mutator T4 DNA polymerase. M S Hershfield, Nancy G Nossal Genetics 1973 pols set
Pathways of nucleotide metabolism in Schistosoma mansoni. IV. Incorporation of adenosine analogs in vitro. R J Stegman, A W Senft, P R Brown, R E Parks Biochem Pharmacol 1973 topics set
Conversion of DNA polymerase extracted from rat ascites hepatoma cells. K Tanabe, Tomonori Takahashi Biochemical and biophysical research communications 1973 new
Transcription and translation of prereplicative bacteriophage T4 genes in vitro. P Z O'Farrell, L Gold The Journal of biological chemistry 1973 topics set
Synthetic template specificity of a deoxyribonucleic acid polymerase from regenerating rat liver. A M de Recondo, J A Lepesant, O Fichot, L Grasset, J M Rossignol, M Cazillis The Journal of biological chemistry 1973 pols set
Letter: Cytoplasmic DNA polymerase: polymeric forms and their conversion into an active monomer resembling nuclear DNA polymerase. L H Lazarus, N Kitron Journal of molecular biology 1973 topics set
DNA polymerase associated with human hepatitis B antigen. P M Kaplan, R L Greenman, J L Gerin, R H Purcell, W S Robinson Journal of virology 1973 topics set
Analysis of nucleotide pools in animal cells. P V Hauschka Methods Cell Biol 1973 new
Infidelity of DNA synthesis by reverse transcriptase. C F Springgate, N Battula, Lawrence A Loeb Biochemical and biophysical research communications 1973 new
Physical characterization and simultaneous purification of bacteriophage T4 induced polynucleotide kinase, polynucleotide ligase, and deoxyribonucleic acid polymerase. A Panet, J H van de Sande, P C Loewen, H G Khorana, A J Raae, J R Lillehaug, K Kleppe Biochemistry 1973 complete
A new form of DNA polymerase 3 and a copolymerase replicate a long, single-stranded primer-template. W Wickner, R Schekman, K Geider, Arthur Kornberg Proceedings of the National Academy of Sciences of the United States of America 1973 complete Joshua Mazzola
Interconvertibility of mouse DNA polymerase activities derived from the nucleus and cytoplasm. N B Hecht Biochimica et biophysica acta 1973 topics set
Antiviral effects of aphidicolin, a new antibiotic produced by Cephalosporium aphidicola. R A Bucknall, H Moores, R Simms, B Hesp Antimicrobial agents and chemotherapy 1973 topics set
Characterization of herpes simplex virus-induced deoxyribonucleic acid polymerase. A Weissbach, S C Hong, J Aucker, R Muller The Journal of biological chemistry 1973 topics set
On the role of deoxyribonucleic acid polymerase in determining mutation rates. Characterization of the defect in the T4 deoxyribonucleic acid polymerase caused by the ts L88 mutation. M S Hershfield The Journal of biological chemistry 1973 partial results
A more sensitive assay system for the detection of RNA-dependent DNA polymerase in oncogenic RNA viruses. Erik De Clercq, P J Claes Biochimica et biophysica acta 1973 new
Investigation of methods for measurement of radioactivity in tritiated DNA and applications to assays for DNA polymerase activity. B K Schrier, Samuel H Wilson Analytical biochemistry 1973 new
Studies on in vitro DNA synthesis. Purification of the dna G gene product from Escherichia coli. S Wickner, M Wright, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1973 new
Studies on in vitro DNA synthesis. II. Isolation of a protein which stimulates deoxynucleotide incorporation catalyzed by DNA polymerase of E. coli. Jerard Hurwitz, S Wickner, M Wright Biochemical and biophysical research communications 1973 pols set
DNA polymerase 3 star requires ATP to start synthesis on a primed DNA. W Wickner, Arthur Kornberg Proceedings of the National Academy of Sciences of the United States of America 1973 complete Joshua Mazzola
Use of DNA polymerase I primed by a synthetic oligonucleotide to determine a nucleotide sequence in phage fl DNA. F Sanger, J E Donelson, A R Coulson, H Kössel, D Fischer Proceedings of the National Academy of Sciences of the United States of America 1973 pols set
Persistence of deoxyribonucleic acid polymerase I and its 5'--3' exonuclease activity in PolA mutants of Escherichia coli K12. I. Robert Lehman, J R Chien The Journal of biological chemistry 1973 pols set
Phi29 bacteriophage structural proteins. G Alvarez, E Salas, N Pérez, J E Celis The Journal of general virology 1972 pols set
Role of genes 46 and 47 in bacteriophage T4 reproduction. II. Formation of gaps on parental DNA of polynucleotide ligase defective mutants. N Prashad, J Hosoda Journal of molecular biology 1972 complete
Studies on DNA synthesis in murine myeloma. II. Activation of latent RNA-dependent DNA polymerase activity in membrane fractions. Samuel H Wilson, E L Kuff, E W Bohn, K K Lueders Biochemical and biophysical research communications 1972 new
Sea urchin nuclear DNA polymerase. IV. Reversible association of DNA polymerase with nuclei during the cell cycle. B Fansler, Lawrence A Loeb Experimental cell research 1972 new
Studies on the induction of DNA polymerase during transformation of human lymphocytes. S S Agarwal, Lawrence A Loeb Cancer research 1972 new
RNA-dependent DNA polymerase activity of RNA tumor viruses. I. Directing influence of DNA in the reaction. Jerard Hurwitz, J P Leis Journal of virology 1972 new
On the direction of reading of bacteriophage T4 gene 43 (deoxyribonucleic acid polymerase). P V O'Donnell, Jim D Karam J Virol 1972 complete
Inactivation of bacteriophage T4 by ethyl methanesulfonate: influence of host and viral genotypes. U Ray, L Bartenstein, J W Drake J Virol 1972 complete
Conversion of phiX174 and fd single-stranded DNA to replicative forms in extracts of Escherichia coli. R B Wickner, M Wright, S Wickner, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1972 new
Activation of a defective DNA polymerase in a temperature-sensitive mutant of bacteriophage T4. M N Swartz, Hiroaki Nakamura, I. Robert Lehman Virology 1972 complete
Isolation and partial characterization of a mutant of Escherichia coli deficient in DNA polymerase II. J L Campbell, L Soll, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 1972 pols set
A new synthetic RNA-dependent DNA polymerase from human tissue culture cells (HeLa-fibroblast-synthetic oligonucleotides-template-purified enzymes). B Fridlender, M Fry, A Bolden, A Weissbach Proceedings of the National Academy of Sciences of the United States of America 1972 topics set
Low molecular weight deoxyribonucleic acid polymerase from rabbit bone marrow. L M Chang, F J Bollum Biochemistry 1972 topics set
Antigenic relationships in mammalian DNA polymerase. L M Chang, F J Bollum Science (New York, N.Y.) 1972 topics set
RNA polymerase from Bacillus amyloliquefaciens. José M Hermoso, J Avila, F Jiménez, Margarita Salas Biochimica et biophysica acta 1972 pols set
Studies on the biochemical basis of spontaneous mutation. I. A comparison of the deoxyribonucleic acid polymerases of mutator, antimutator, and wild type strains of bacteriophage T4. N Muzyczka, R L Poland, M J Bessman The Journal of biological chemistry 1972 complete
Mutagen stability of alkylation-sensitive mutants of Bacillus subtilis. T Hill, Louise Prakash, B Strauss Journal of bacteriology 1972 new
Deoxyribonucleic acid polymerase: two distinct enzymes in one polypeptide. I. A proteolytic fragment containing the polymerase and 3' leads to 5' exonuclease functions. P Setlow, D Brutlag, Arthur Kornberg The Journal of biological chemistry 1972 complete Joshua Mazzola
Temperature-sensitive mutants affected in DNA synthesis in phage phi29 of Bacillus subtilis. A Talavera, Margarita Salas, E Viñuela Eur J Biochem 1972 pols set
Degradation of DNA RNA hybrids by ribonuclease H and DNA polymerases of cellular and viral origin. W Keller, R Crouch Proceedings of the National Academy of Sciences of the United States of America 1972 new
An analysis of replication errors made by a defective T4 DNA polymerase. F A de Vries, C J Swart-Idenburg, A de Waard Mol Gen Genet 1972 complete
Enzymatic synthesis of deoxyribonucleic acid. 36. A proofreading function for the 3' leads to 5' exonuclease activity in deoxyribonucleic acid polymerases. D Brutlag, Arthur Kornberg The Journal of biological chemistry 1972 complete
A novel DNA polymerase activity found in association with intracisternal A-type particles. Samuel H Wilson, E L Kuff Proceedings of the National Academy of Sciences of the United States of America 1972 new
Deoxyribonucleic acid polymerase: two distinct enzymes in one polypeptide. II. A proteolytic fragment containing the 5' leads to 3' exonuclease function. Restoration of intact enzyme functions from the two proteolytic fragments. P Setlow, Arthur Kornberg The Journal of biological chemistry 1972 complete Joshua Mazzola
On the direction of translation of the T4 deoxyribonucleic acid polymerase gene in vivo. W M Huang, I. Robert Lehman The Journal of biological chemistry 1972 partial results
RNA-dependent DNA polymerase activity of RNA tumor viruses. II. Directing influence of RNA in the reaction. J P Leis, Jerard Hurwitz Journal of virology 1972 new
On the exonuclease activity of phage T4 deoxyribonucleic acid polymerase. W M Huang, I. Robert Lehman The Journal of biological chemistry 1972 partial results
Head-neck connecting protein in phage phi29. G Ramírez, E Méndez, Margarita Salas, E Viñuela Virology 1972 pols set
Deoxyribonucleic acid synthesis in cell-free extracts. IV. Purification and catalytic properties of deoxyribonucleic acid polymerase III. T Kornberg, M L Gefter The Journal of biological chemistry 1972 topics set
Studies on vaccinia virus-directed deoxyribonucleic acid polymerase. R V Citarella, R Muller, A Schlabach, A Weissbach Journal of virology 1972 topics set
Association of an endoribonuclease with the avian myeloblastosis virus deoxyribonucleic acid polymerase. D Baltimore, D F Smoler The Journal of biological chemistry 1972 new
The mechanism of Escherichia coli deoxyribonucleic acid polymerase I. Magnetic resonance and kinetic studies of the role of metals. J P Slater, I Tamir, Lawrence A Loeb, A S Mildvan The Journal of biological chemistry 1972 topics set
Depression of DNA polymerase activity in chromatin by incubation with NAD. M Nagao, Masami Yamada, M Miwa, T Sugimura Biochemical and biophysical research communications 1972 pols set
Hydrolysis of template and newly synthesized deoxyribonucleic acid by the 3' to 5' exonuclease activity of the T4 deoxyribonucleic acid polymerase. M S Hershfield, Nancy G Nossal The Journal of biological chemistry 1972 complete
Nuclease activity in a fragment of bacteriophage T4 deoxyribonucleic acid polymerase induced by the amber mutant am B22. Nancy G Nossal, M S Hershfield The Journal of biological chemistry 1971 complete
Purification and characterization of a deoxyribonucleic acid polymerase from rat liver. H Berger, R C Huang, J L Irvin The Journal of biological chemistry 1971 topics set
Some irregularities in the nomenclature of bacteriophage T4 DNA polymerase amber mutants. J W Drake Genetics 1971 pols set
DNA polymerase associated with nuclear membrane of calf thymus. S Yoshida, M J Modak, K Yagi Biochemical and biophysical research communications 1971 new
Properties of a soluble DNA polymerase isolated from Rous sarcoma virus. P Duesberg, K V Helm, E Canaani Proceedings of the National Academy of Sciences of the United States of America 1971 new
Deoxyribonucleic acid polymerase of bacteriophage T7. P Grippo, Charles C Richardson The Journal of biological chemistry 1971 partial results
The influence of neighboring base pairs upon base-pair substitution mutation rates. R E Koch Proceedings of the National Academy of Sciences of the United States of America 1971 topics set
Electron microscopy of DNA polymerase bound to DNA. J Griffith, J A Huberman, Arthur Kornberg Journal of molecular biology 1971 new
Deoxyribonucleic acid polymerase with rat liver ribosomes and smooth membranes. Purification and properties of the enzymes. E F Baril, O E Brown, M D Jenkins, J Laszlo Biochemistry 1971 topics set
DNA polymerases from human cells. A Weissbach, A Schlabach, B Fridlender, A Bolden Nature: New biology 1971 topics set
Purification and properties of DNA-dependent RNA polymerase from Bacillus subtilis vegetative cells. J Avila, José M Hermoso, E Vinuela, Margarita Salas Eur J Biochem 1971 pols set
Strand displacement during deoxyribonucleic acid synthesis at single strand breaks. Y Masamune, Charles C Richardson The Journal of biological chemistry 1971 topics set
RNA-dependent DNA polymerase in human lymphocytes during gene activation by phytohaemagglutinin. P E Penner, L H Cohen, Lawrence A Loeb Nature: New biology 1971 new
Reversion of frameshift mutations stimulated by lesions in early function genes of bacteriophage T4. H Bernstein J Virol 1971 complete
Purification and DNA synthesis in cell-free extracts: properties of DNA polymerase II. T Kornberg, M L Gefter Proceedings of the National Academy of Sciences of the United States of America 1971 partial results
Two decades of research on the biosynthesis of saccharides. L F Leloir Science (New York, N.Y.) 1971 topics set
In vitro DNA synthesis in the presence of antibody to homogeneous E. coli DNA polymerase. Lawrence A Loeb, J P Slater, J L Ewald, S S Agarwal Biochemical and biophysical research communications 1971 pols set
Distinct cytoplasmic and nuclear DNA polymerases from rat liver. M E. Haines, A M. Holmes, I R. Johnston FEBS letters 1971 topics set
Purification of the DNA polymerase of avian myeloblastosis virus. D L Kacian, K F Watson, A Burny, S Spiegelman Biochimica et biophysica acta 1971 new
Association of viral reverse transcriptase with an enzyme degrading the RNA moiety of RNA-DNA hybrids. K Mölling, D P Bolognesi, H Bauer, W Büsen, H W Plassmann, P Hausen Nat New Biol 1971 new
Stimulation of T4 bacteriophage DNA polymerase by the protein product of T4 gene 32. J A Huberman, Arthur Kornberg, B M Alberts Journal of molecular biology 1971 new
Analysis of nucleotide sequences at 3' termini of duplex deoxyribonucleic acid with the use of the T4 deoxyribonucleic acid polymerase. Paul T Englund The Journal of biological chemistry 1971 new
[Recent studies on the active center of Escherichia coli DNA polymerase]. Arthur Kornberg Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1971 pols set
Interaction between DNA and an Escherichia coli protein omega. J C Wang Journal of molecular biology 1971 topics set
Low molecular weight deoxyribonucleic acid polymerase in mammalian cells. L M Chang, F J Bollum The Journal of biological chemistry 1971 topics set
Lymphocyte transformation and hepatitis. I. Impairment of thymidine incorporation and DNA polymerase activity. S S Agarwal, B S Blumberg, B J Gerstley, W T London, I Millman, A I Sutnick, Lawrence A Loeb Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1971 new
RNA-dependent DNA polymerase: presence in normal human cells. P E Penner, L H Cohen, Lawrence A Loeb Biochemical and biophysical research communications 1971 new
The initial step of in vitro synthesis of deoxyribonucleic acid by the T4 deoxyribonucleic acid polymerase. Paul T Englund The Journal of biological chemistry 1971 complete
Deoxyribonucleic acid synthesis in mammalian nuclei. Incorporation of deoxyribonucleotides and chain-terminating nucleotide analogues. M A Waqar, L A Burgoyne, M R Atkinson Biochem J 1971 topics set
DNA polymerase. Correlation with DNA replication during transformation of human lymphocytes. Lawrence A Loeb, S S Agarwal Experimental cell research 1971 new
Comparative properties of RNA and DNA templates for the DNA polymerase of Rous sarcoma virus. P Duesberg, K V Helm, E Canaani Proceedings of the National Academy of Sciences of the United States of America 1971 new
RNA-dependent DNA polymerase in virions of Rous sarcoma virus. H M Temin, S Mizutani Nature 1970 topics set
Mechanism of carcinogenesis by RNA tumor viruses. 3. Formation of RNA, DNA complex and duplex DNA molecules by the DNA polymerase (s) of avian myeloblastosis virus. K Fujinaga, J T Parsons, J W Beard, D Beard, M Green Proceedings of the National Academy of Sciences of the United States of America 1970 partial results
Function of gene 32-protein, a new protein essential for the genetic recombination and replication of T4 bacteriophage DNA. B M Alberts Federation proceedings 1970 topics set
DNA polymerase and DNA replication during lymphocyte transformation. Lawrence A Loeb, J L Ewald, S S Agarwal Cancer research 1970 new
Studies on the pathway of incorporation of 2-aminopurine into the deoxyribonucleic acid of Escherichia coli. EG Rogan, MJ Bessman Journal of bacteriology 1970 new
DNA polymerase II. R Knippers Nature 1970 topics set
Selective elimination of the exonuclease activity of the deoxyribonucleic acid polymerase from Escherichia coli B by limited proteolysis. H Klenow, I Henningsen Proceedings of the National Academy of Sciences of the United States of America 1970 partial results
DNA polymerase activity as an index of lymphocyte stimulation: studies in Down's syndrome. S S Agarwal, B S Blumberg, B J Gerstley, W T London, A I Sutnick, Lawrence A Loeb The Journal of clinical investigation 1970 new
Suppression of chemical mutagenesis in bacteriophage T4 by genetically modified DNA polymerases. John W Drake, E O Greening Proceedings of the National Academy of Sciences of the United States of America 1970 topics set
T4 bacteriophage gene 32: a structural protein in the replication and recombination of DNA. B M Alberts, L Frey Nature 1970 topics set
Viral DNA-dependent DNA polymerase and the properties of thymidine labelled material in virions of an oncogenic RNA virus. J Ríman, G S Beaudreau Nature 1970 new
Subunit composition of B. subtilis RNA polymerase. J Avila, José M Hermoso, E Viñuela, Margarita Salas Nature 1970 pols set
Enzymatic synthesis of deoxyribonucleic acid. XXXV. A 3'-hydroxylribonucleotide binding site of Escherichia coli deoxyribonucleic acid polymerase. J A Huberman, Arthur Kornberg The Journal of biological chemistry 1970 complete Joshua Mazzola
Intracellular migration of DNA polymerase in early developing sea urchin embryos. Lawrence A Loeb, B Fansler Biochimica et biophysica acta 1970 new
Cryptic mutants of bacteriophage T4. R E Koch, John W Drake Genetics 1970 complete
DNA-directed DNA polymerase activity in oncogenic RNA viruses. S Spiegelman, A Burny, M R Das, J Keydar, J Schlom, M Travnicek, K Watson Nature 1970 new
Studies on deoxyribonucleic acid polymerases from yeast. 2. Partial purification and characterization of mitochondrial DNA polymerase from wild type and respiration-deficient yeast cells. U Wintersberger, E Wintersberger European journal of biochemistry / FEBS 1970 topics set
A new DNA polymerase acitvity of Escherichia coli. II. Properties of the enzyme purified from wild-type E. coli and DNA-ts mutants. Robb E Moses, Charles C Richardson Biochemical and biophysical research communications 1970 topics set
RNA-dependent DNA polymerase in virions of RNA tumour viruses. D Baltimore Nature 1970 topics set
Enzymatic synthesis of deoxyribonucleic acid. XXXII. Replication of duplex deoxyribonucleic acid by polymerase at a single strand break. R B Kelly, N R Cozzarelli, M P Deutscher, I. Robert Lehman, Arthur Kornberg The Journal of biological chemistry 1970 complete Joshua Mazzola
Induction of DNA polymerase in mixed lymphocyte cultures. S S Agarwal, S J Bugbee, Lawrence A Loeb Nature 1970 new
A new DNA polymerase activity of Escherichia coli. I. Purification and properties of the activity present in E. coli polA1. Robb E Moses, Charles C Richardson Biochemical and biophysical research communications 1970 topics set
DNA synthesis in cell-free extracts of a DNA polymerase-defective mutant. T Kornberg, M L Gefter Biochemical and biophysical research communications 1970 topics set
Properties of bacteriophage T4 mutants defective in DNA polymerase. E F Allen, I Albrecht, John W Drake Genetics 1970 topics set
Enzymic synthesis of DNA. 33. Hydrolysis of a 5'-triphosphate-terminated polynucleotide in the active center of DNA polymerase. N R Cozzarelli, R B Kelly, Arthur Kornberg Journal of molecular biology 1969 new
Sea urchin nuclear DNA polymerase. I. Localization in nuclei during rapid DNA synthesis. Lawrence A Loeb, B Fansler, R Williams, D Mazia Experimental cell research 1969 new
Enzymatic synthesis of deoxyribonucleic acid. XXXI. Binding of deoxyribonucleic acid to deoxyribonucleic acid polymerase. Paul T Englund, R B Kelly, Arthur Kornberg The Journal of biological chemistry 1969 complete Joshua Mazzola
Enzymatic synthesis of deoxyribonucleic acid. XXVI. Physical and chemical studies of a homogeneous deoxyribonucleic acid polymerase. T M Jovin, Paul T Englund, L L Bertsch The Journal of biological chemistry 1969 complete Joshua Mazzola
A T4 bacteriophage mutant which lacks deoxyribonucleic acid polymerase but retains the polymerase-associated nuclease. Nancy G Nossal The Journal of biological chemistry 1969 new
Enzymatic synthesis of deoxyribonucleic acid. 28. The pyrophosphate exchange and pyrophosphorolysis reactions of deoxyribonucleic acid polymerase. M P Deutscher, Arthur Kornberg The Journal of biological chemistry 1969 complete Joshua Mazzola
Enzymatic synthesis of deoxyribonucleic acid. XXIX. Hydrolysis of deoxyribonucleic acid from the 5' terminus by an exonuclease function of deoxyribonucleic acid polymerase. M P Deutscher, Arthur Kornberg The Journal of biological chemistry 1969 complete Joshua Mazzola
Active center of DNA polymerase. Arthur Kornberg Science (New York, N.Y.) 1969 new
Enzymatic synthesis of deoxyribonucleic acid. XXX. Binding of triphosphates to deoxyribonucleic acid polymerase. Paul T Englund, J A Huberman, T M Jovin, Arthur Kornberg The Journal of biological chemistry 1969 complete Joshua Mazzola
An active fragment of DNA polymerase produced by proteolytic cleavage. D Brutlag, M R Atkinson, P Setlow, Arthur Kornberg Biochemical and biophysical research communications 1969 new
Sea urchin nuclear DNA polymerase. II. Changing localization during early development. B Fansler, Lawrence A Loeb Experimental cell research 1969 new
Isolation of an E. coli strain with a mutation affecting DNA polymerase. P De Lucia, J Cairns Nature 1969 topics set
Rifampicin sensitivity of the components of DNA-dependent RNA polymerase. E di Mauro, L Synder, P Marino, A Lamberti, A Coppo, G P Tocchini-Valentini Nature 1969 new
Enzymatic synthesis of deoxyribonucleic acid. XXVII. Chemical modifications of deoxyribonucleic acid polymerase. T M Jovin, Paul T Englund, Arthur Kornberg The Journal of biological chemistry 1969 complete Joshua Mazzola
Separation of a new deoxyribonucleic acid polymerase from vaccinia-infected HeLa cells. K I Berns, C Silverman, A Weissbach Journal of virology 1969 topics set
The enzymatic termination of polydeoxynucleotides by 2',3'-dideoxyadenosine triphosphate. L Toji, S S Cohen Proceedings of the National Academy of Sciences of the United States of America 1969 topics set
Enzymatic synthesis of deoxyribonucleic acid. XXXIV. Termination of chain growth by a 2',3'-dideoxyribonucleotide. M R Atkinson, M P Deutscher, Arthur Kornberg, A F Russell, J G Moffatt Biochemistry 1969 new
An in vitro transversion by a mutationally altered T4-induced DNA polymerase. Z W Hall, I. Robert Lehman Journal of molecular biology 1968 new
The function of T4 DNA polymerase. J F Speyer, D Rosenberg Cold Spring Harbor symposia on quantitative biology 1968 topics set
Studies on the synthesis of deoxyribonucleic acid. I. Further purification and properties of the deoxyribonucleic acid polymerase induced by infection of Escherichia coli with bacteriophage T5. CD Steuart, SR Anand, MJ Bessman The Journal of biological chemistry 1968 pols set
Enzymatic synthesis of deoxyribonucleic acid. XXV. Purification and properties of deoxyribonucleic acid polymerase induced by infection with phage T4. Mehran Goulian, Z J Lucas, Arthur Kornberg The Journal of biological chemistry 1968 complete Joshua Mazzola
Induction of DNA polymerase in human lymphocytes by phytohemagglutinin. Lawrence A Loeb, S S Agarwal, A M Woodside Proceedings of the National Academy of Sciences of the United States of America 1968 new
Mechanism of DNA chain growth. I. Possible discontinuity and unusual secondary structure of newly synthesized chains. R Okazaki, T Okazaki, K Sakabe, K Sugimoto, Akio Sugino Proceedings of the National Academy of Sciences of the United States of America 1968 topics set
Exonuclease VI, a new nuclease activity associated with E. coli DNA polymerase. R P Klett, A Cerami, E Reich Proceedings of the National Academy of Sciences of the United States of America 1968 pols set
Antimutagenic DNA polymerases of bacteriophage T4. John W Drake, E F Allen Cold Spring Harbor symposia on quantitative biology 1968 topics set
Studies with DNA-cellulose chromatography. I. DNA-binding proteins from Escherichia coli. B M Alberts, F J Amodio, M Jenkins, E D Gutmann, F L Ferris Cold Spring Harbor symposia on quantitative biology 1968 topics set
Structural and functional properties of Escherichia coli DNA polymerase. Paul T Englund, M P Deutscher, T M Jovin, R B Kelly, N R Cozzarelli, Arthur Kornberg Cold Spring Harbor symposia on quantitative biology 1968 pols set
Repair and recombination in phage T4. II. Genes affecting UV sensitivity. M W Baldy Cold Spring Harbor symposia on quantitative biology 1968 complete
Enzymatic breakage and joining of deoxyribonucleic acid, I. Repair of single-strand breaks in DNA by an enzyme system from Escherichia coli infected with T4 bacteriophage. B Weiss, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 1967 topics set
The enzymatic repair of DNA. I. Formation of circular lambda-DNA. M L Gefter, A Becker, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 1967 topics set
Formation of covalent circles of lambda DNA by E. coli extracts. M Gellert Proceedings of the National Academy of Sciences of the United States of America 1967 topics set
Polynucleotide cellulose as a substrate for a polynucleotide ligase induced by phage T4. N R Cozzarelli, N E Melechen, T M Jovin, Arthur Kornberg Biochemical and biophysical research communications 1967 topics set
Priming of DNA polymerase in nuclei of sea urchin embryos by native DNA. Lawrence A Loeb, D Mazia, A D Ruby Proceedings of the National Academy of Sciences of the United States of America 1967 new
Characteristics of mutations appearing spontaneously in extracellular particles of bacteriophage T4. John W Drake, J McGuire Genetics 1967 topics set
The effect on recombination of mutational defects in the DNA-polymerase and deoxycytidylate hydroxymethylase of phage T4D. H Bernstein Genetics 1967 complete
Enzymatic synthesis of DNA. 23. Synthesis of circular replicative form of phage phi-X174 DNA. Mehran Goulian, Arthur Kornberg Proceedings of the National Academy of Sciences of the United States of America 1967 topics set
Linkage of polynucleotides through phosphodiester bonds by an enzyme from Escherichia coli. B M Olivera, I. Robert Lehman Proceedings of the National Academy of Sciences of the United States of America 1967 topics set
Enzymatic joining of DNA strands: a novel reaction of diphosphopyridine nucleotide. S B Zimmerman, J W Little, C K Oshinsky, M Gellert Proceedings of the National Academy of Sciences of the United States of America 1967 topics set
Synchronized yeast cells. 3. DNA synthesis and DNA polymerase after inhibition of cell division by x-rays. H Eckstein, V Paduch, H Hilz European journal of biochemistry / FEBS 1967 topics set
Immunological evidence for a specific DNA polymerase produced after infection by herpes simplex virus. H M Keir, H Subak-Sharpe, W I Shedden, D H Watson, P Wildy Virology 1966 topics set
Occurrence of a DNA-polymerase in isolated yeast mitochondria. E Wintersberger Biochemical and biophysical research communications 1966 topics set
On the role of DNA polymerase in base selection. J F Speyer, Jim D Karam, A B Lenny Cold Spring Harbor symposia on quantitative biology 1966 complete
Biochemical studies of bacterial sporulation. II. Deoxy- ribonucleic acid polymerase in spores of Bacillus subtilis. A Falaschi, Arthur Kornberg The Journal of biological chemistry 1966 new
Deoxyribonucleic acid synthesis in Escherichia coli infected with some deoxyribonucleic acid polymerase-less mutants of bacteriophage T4. H R Warner, J E Barnes Virology 1966 topics set
Separation of deoxyribo-oligonucleotidases induced by infection with bacteriophage T2. E C Short, J F Koerner Proceedings of the National Academy of Sciences of the United States of America 1965 partial results
DEOXYNUCLEOTIDE-POLYMERIZING ENZYMES OF CALF THYMUS GLAND. I. LARGE SCALE PURIFICATION OF TERMINAL AND REPLICATIVE DEOXYNUCLEOTIDYL TRANSFERASES. M YONEDA, F J Bollum The Journal of biological chemistry 1965 complete Joshua Mazzola
ENZYMIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. XX. ELECTRON MICROSCOPY OF PRODUCTS PRIMED BY NATIVE TEMPLATES. R B INMAN, C L SCHILDKRAUT, Arthur Kornberg Journal of molecular biology 1965 new
The enzymology of virus-infected bacteria. VII. A new deoxyribonucleic acid polymerase induced by bacteriophage T5. CW Orr, ST Herriott, MJ Bessman The Journal of biological chemistry 1965 new
The structural gene for deoxyribonucleic acid polymerase in bacteriophages T4 and T5. A De Waard, A V Paul, I. Robert Lehman Proceedings of the National Academy of Sciences of the United States of America 1965 complete
Mutagenic DNA polymerase. J F Speyer Biochem Biophys Res Commun 1965 new
HOMOLOGY BETWEEN RNA FROM ROUS SARCOMA VIROUS AND DNA FROM ROUS SARCOMA VIRUS-INFECTED CELLS. H M TEMIN Proceedings of the National Academy of Sciences of the United States of America 1964 new
ENZYMIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. 18. THE REPAIR OF PARTIALLY SINGLE-STRANDED DNA TEMPLATES BY DNA POLYMERASE. Charles C Richardson, R B INMAN, Arthur Kornberg Journal of molecular biology 1964 new
THE DEOXYRIBONUCLEASES OF ESCHERICHIA COLI. IV. AN EXONUCLEASE ACTIVITY PRESENT IN PURIFIED PREPARATIONS OF DEOXYRIBONUCLEIC ACID POLYMERASE. I. Robert Lehman, Charles C Richardson The Journal of biological chemistry 1964 complete Joshua Mazzola
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. XIV. FURTHER PURIFICATION AND PROPERTIES OF DEOXYRIBONUCLEIC ACID POLYMERASE OF ESCHERICHIA COLI. Charles C Richardson, C L SCHILDKRAUT, H V APOSHIAN, Arthur Kornberg The Journal of biological chemistry 1964 complete Joshua Mazzola
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID, XVI. OLIGONUCLEOTIDES AS TEMPLATES AND THE MECHANISM OF THEIR REPLICATION. Arthur Kornberg, L L BERTSCH, J F JACKSON, H G KHORANA Proceedings of the National Academy of Sciences of the United States of America 1964 complete Joshua Mazzola
ENZYMIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. XVII. SOME UNUSUAL PHYSICAL PROPERTIES OF THE PRODUCT PRIMED BY NATIVE DNA TEMPLATES. C L SCHILDKRAUT, Charles C Richardson, Arthur Kornberg Journal of molecular biology 1964 new
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. XV. PURIFICATION AND PROPERTIES OF A POLYMERASE FROM BACILLUS SUBTILIS. T OKAZAKI, Arthur Kornberg The Journal of biological chemistry 1964 complete Joshua Mazzola
ANTIMETABOLITES AFFECTING PROTEIN OR NUCLEIC ACID SYNTHESIS. PHLEOMYCIN, AN INHIBITOR OF DNA POLYMERASE. A Falaschi, Arthur Kornberg Federation proceedings 1964 new
THE PARTICIPATION OF DNA IN ROUS SARCOMA VIRUS PRODUCTION. H M TEMIN Virology 1964 new
Physiological Studies of Conditional Lethal mutants of Bacteriophage T4D Cold Spring Harbor symposia on quantitative biology 1963 complete
Oligodeoxyribonucleotide-primed reactions catalyzed by calf thymus polymerase. F J Bollum The Journal of biological chemistry 1962 complete Joshua Mazzola
Enzymatic synthesis of deoxyribonucleic acid. XIII. Kinetics of primed and de novo synthesis of deoxynucleotide polymers. C M RADDING, Arthur Kornberg The Journal of biological chemistry 1962 new
Enzymatic synthesis of deoxyribonucleic acid. IX. The polymerase formed after T2 bacteriophage infection of Escherichia coli: a new enzyme. H V APOSHIAN, Arthur Kornberg The Journal of biological chemistry 1962 complete Joshua Mazzola
Enzymatic synthesis of deoxyribonucleic acid. XII. A polymer of deoxyguanylate and deoxycytidylate. C M RADDING, J JOSSE, Arthur Kornberg The Journal of biological chemistry 1962 complete Joshua Mazzola
Enzymatic synthesis of deoxyribonucleic acid. VIII. Frequencies of nearest neighbor base sequences in deoxyribonucleic acid. J JOSSE, A D KAISER, Arthur Kornberg The Journal of biological chemistry 1961 complete Joshua Mazzola
Calf thymus polymerase. F J BOLLUM The Journal of biological chemistry 1960 complete Joshua Mazzola
Enzymatic synthesis of deoxyribonucleic acid. VII. Synthesis of a polymer of deoxyadenylate and deoxythymidylate. H K SCHACHMAN, J Adler, C M RADDING, I. Robert Lehman, Arthur Kornberg The Journal of biological chemistry 1960 complete Joshua Mazzola
Enzymatic synthesis of deoxyribonucleic acid. Arthur Kornberg Harvey lectures 1959 topics set
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. IV. LINKAGE OF SINGLE DEOXYNUCLEOTIDES TO THE DEOXYNUCLEOSIDE ENDS OF DEOXYRIBONUCLEIC ACID. J Adler, I. Robert Lehman, M J Bessman, E S Simms, Arthur Kornberg Proceedings of the National Academy of Sciences of the United States of America 1958 complete Joshua Mazzola
Incorporation of thymidine into deoxyribonucleic acid by enzymes from rat tissues. F J Bollum, V R POTTER The Journal of biological chemistry 1958 complete Joshua Mazzola
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. V. CHEMICAL COMPOSITION OF ENZYMATICALLY SYNTHESIZED DEOXYRIBONUCLEIC ACID. I. Robert Lehman, S B Zimmerman, J Adler, M J Bessman, E S Simms, Arthur Kornberg Proceedings of the National Academy of Sciences of the United States of America 1958 complete Joshua Mazzola
Enzymatic synthesis of deoxyribonucleic acid. I. Preparation of substrates and partial purification of an enzyme from Escherichia coli. I. Robert Lehman, M J Bessman, E S Simms, Arthur Kornberg The Journal of biological chemistry 1958 complete Joshua Mazzola
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. III. THE INCORPORATION OF PYRIMIDINE AND PURINE ANALOGUES INTO DEOXYRIBONUCLEIC ACID. M J Bessman, I. Robert Lehman, J Adler, S B Zimmerman, E S Simms, Arthur Kornberg Proceedings of the National Academy of Sciences of the United States of America 1958 complete Joshua Mazzola
Enzymatic synthesis of deoxyribonucleic acid. II. General properties of the reaction. M J Bessman, I. Robert Lehman, E S Simms, Arthur Kornberg The Journal of biological chemistry 1958 complete Joshua Mazzola
Enzymic synthesis of deoxyribonucleic acid. M J Bessman, Arthur Kornberg, I. Robert Lehman, E S Simms Biochimica et biophysica acta 1956 complete Joshua Mazzola
Studies of deoxyribonucleic acid biosynthesis in embryonic tissues with thymidine-C14. M FRIEDKIN, D TILSON, D ROBERTS The Journal of biological chemistry 1956 complete Joshua Mazzola
Utilization of thymidine-C14 by bone marrow cells and isolated thymus nuclei. M FRIEDKIN, H I V WOOD The Journal of biological chemistry 1956 topics set
Enzymatic synthesis of nucleic acidlike polynucleotides. M GRUNBERG-MANAGO, P J ORITZ, S OCHOA Science (New York, N.Y.) 1955 topics set
The correlation of growth with incorporation of radioactive metabolites into nucleic acids in embryonic tissue culture. K H LU, T WINNICK Experimental cell research 1954 topics set
Utilization of desoxyribosides in the synthesis of polynucleotides. P REICHARD, B ESTBORN The Journal of biological chemistry 1951 topics set

Version:20240508

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.