show help

References

Welcome to the reference index page

This page displays summary information about all the references in Polbase. Select one of the reference titles to see more information about it.

Choose the "with structures only" box to limit this list to only those references that report an experimentally determined structure.

Using Polbase tables:

Sorting:

Tables may be sorted by clicking on any of the column titles. A second click reverses the sort order. <Ctrl> + click on the column titles to sort by more than one column (e.g. family then name).

Filtering:

It is also possible to filter the table by typing into the search box above the table. This will instantly hide lines from the table that do not contain your search text.

Help icons:

The show help symbol in the upper-right corner of the page links to this help text. The question mark icon is used everywhere to indicate that help is available.


Title Authors Journal Year Status Validated by
Urinary tract infection drives genome instability in uropathogenic Escherichia coli and necessitates translesion synthesis DNA polymerase IV for virulence. Damian Gawel, Patrick C Seed Virulence topics set
? new
? new
? new
? new
? new
? new
? new
? new
? new
? new
? new
? new
? new
The role of Tat in HIV-1 replication: an activator and/or a suppressor? Chen Liang, Mark A. Wainberg AIDS reviews pols set
? new
? new
? new
? new
? new
? new
? new
? new
? new
? new
A review of recent experiments on step-to-step "hand-off" of the DNA intermediates in mammalian base excision repair pathways. Rajendra Prasad, William A Beard, Vinod K Batra, Yuan Liu, David D Shock, Samuel H Wilson Molekuliarnaia biologiia new
? new
? new
? new
? new
? new
Localization of the large subunit of replication factor C near the 5' end of DNA primers. Dmitry M Kolpashchikov, Patrick Hughes, Alain Favre, Giuseppe Baldacci, Olga I Lavrik Journal of molecular recognition : JMR new
? new
? new
Zhonghua yi xue za zhi new
? new
? new
Journal of virological methods topics set
? new
? new
DNA repair topics set
[Preparation of photoreactive oligonucleotide duplexes and their application for photoaffinity modification of DNA-binding proteins]. D Iu Khlimankov, Irina O Petruseva, Nadejda I Rechkunova, Ekaterina A Belousova, Dmitry M Kolpashchikov, Svetlana N Khodyreva, Olga I Lavrik Bioorganicheskaia khimiia new
? new
? new
Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues. Y Kuchino, F Mori, Hironori Kasai, H Inoue, Shigenori Iwai, K Miura, E Ohtsuka, Susumu Nishimura Nature pols set
? new
[Isolation and characteristics of endonuclease tightly bound to alpha-polymerase from the rat liver]. N A Timchenko, I V Shevelev, S N Drobchenko, O P Zhuchenko, V M Krutiakov Molekuliarnaia biologiia new
? new
? new
? new
[Interaction of human replication protein A with DNA-duplexes, containing gaps of varying sizes]. D Iu Khlimankov, Nadejda I Rechkunova, Dmitry M Kolpashchikov, Irina O Petruseva, Svetlana N Khodyreva, A Favr, Olga I Lavrik Molekuliarnaia biologiia new
[Interaction of replication protein A and flap endonuclease 1 with DNA duplexes containing a nick or flap]. D Iu Khlimankov, Nadejda I Rechkunova, Svetlana N Khodyreva, Irina O Petruseva, Zh K Nazarkina, Ekaterina A Belousova, Olga I Lavrik Molekuliarnaia biologiia new
Synthesis of base-substituted dUTP analogues carrying a photoreactive group and their application to study human replication protein A. Dmitry M Kolpashchikov, T M Ivanova, V S Boghachev, Heinz Peter Nasheuer, Klaus Weisshart, Alain Favre, P E Pestryakov, Olga I Lavrik Bioconjugate chemistry new
? new
Antonia A Nemec ? new
A new highly efficient photoreactive analogue of dCTP. Synthesis, characterization, and application in photoaffinity modification of DNA binding proteins. Sergey V Dezhurov, Svetlana N Khodyreva, Ekaterina S Plekhanova, Olga I Lavrik Bioconjugate chemistry new
? new
? new
? new
? new
[Flap endonuclease-1 and its role in the processes of DNA metabolism in eucaryotic cells]. Zh K Nazarkina, Olga I Lavrik, Svetlana N Khodyreva Molekuliarnaia biologiia new
? new
? new
? new
? new
? new
DNA synthesis enzymes and proliferating cell nuclear antigen in normal and neoplastic nerve cells. A Verri, S Verzeletti, P Mazzarello, Silvio Spadari, M Negri, G Bunone, G Della Valle, Ulrich Hübscher, Federico Focher Anticancer research new
[Photoaffinity modification of human immunodeficiency virus reverse transcriptase with an analog of deoxyuridine-5'-triphosphate, containing an arylazide group]. N V Shcherbik, Svetlana N Khodyreva, V A Vlasov, M I Dobrikov, G M Dymshits, Olga I Lavrik Molekuliarnaia biologiia new
HIV-reverse transcriptase and human DNA polymerase alpha share amino acid sequence homologies to bacterial penicillin-binding proteins. P Hafkemeyer, K A Neftel, Ulrich Hübscher Methods and findings in experimental and clinical pharmacology pols set
[3'-->5'-exonucleases of the rat liver and the correction of replication errors]. N V Beliakova, N E Kleĭner, T P Kravetskaia, O K Legina, S N Naryzhnyĭ, F V Perrino, I V Shevelev, V M Krutiakov Izvestiia Akademii nauk SSSR. Seriia biologicheskaia new
? new
Jianhong Wu ? new
Mutagenesis dependent upon the combination of activation-induced deaminase expression and a double-strand break. Vladimir P Poltoratsky, Michelle L Heacock, Grace E Kissling, Rajendra Prasad, Samuel H Wilson Molecular immunology new
Jianhong Wu ? new
[Polymorphism of 5' promotor region of mitochondrial gamma-DNA-polymerase gene in human populations]. B A Maliarchuk, M A Perkova, Miroslava V Derenko Molekuliarnaia biologiia new
N-3 substituted TSAO derivatives as a probe to explore the dimeric interface of HIV-1 reverse transcriptase. María-Cruz Bonache, Cristina Chamorro, Sonsoles Velázquez, Erik De Clercq, Jan Balzarini, María-José Camarasa, Ana San-Félix Nucleosides, nucleotides & nucleic acids pols set
Revista do Instituto de Medicina Tropical de Sao Paulo topics set
In vitro study of resistance-associated genotypic mutations to nucleoside analogs. N Gashnikova, O Plyasunova, Y Kiseleva, N Fedyuk, A Pokrovsky Nucleosides, nucleotides & nucleic acids pols set
Perspectives of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the therapy of HIV-1 infection. Erik De Clercq Farmaco (Società chimica italiana : 1989) pols set
Novel compounds in preclinical/early clinical development for the treatment of HIV infections. Erik De Clercq Reviews in medical virology pols set
Discovery, development and characterization of agents active against the AIDS virus. Rudi Pauwels, M P de Bethune, Koen Andries, Paul Stoffels, P Janssen, Erik De Clercq Journal of receptor and signal transduction research pols set
Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: clinical and molecular genetic study. Petri Luoma, Atle Melberg, Juha O Rinne, Jyrki A Kaukonen, Nina N Nupponen, Richard M Chalmers, Anders Oldfors, Ilkka Rautakorpi, Leena Peltonen, Kari Majamaa, Hannu Somer, Anu Suomalainen Lancet pols set
Role of genetic diversity amongst HIV-1 non-B subtypes in drug resistance: a systematic review of virologic and biochemical evidence. Jorge L Martínez-Cajas, Nitika Pant-Pai, Marina B Klein, Mark A. Wainberg AIDS reviews pols set
Enhanced inhibition of HIV-1 replication in macrophages by antisense oligonucleotides, ribozymes and acyclic nucleoside phosphonate analogs delivered in pH-sensitive liposomes. N Düzgünes, S Simões, V Slepushkin, E Pretzer, J J Rossi, Erik De Clercq, V P Antao, M L Collins, M C de Lima Nucleosides, nucleotides & nucleic acids pols set
Human DNA Polymerase-beta Promoter: Phorbol Ester Activation Is Mediated through the cAMP Response Element and cAMP-Response-Element-Binding Protein. X.-P. Yang, Feng He, Teresa Y Rawson, Samuel H Wilson Journal of biomedical science pols set
[RNA-dependent DNA-polymerase from avian myeloblastosis virus: effectiveness of interaction with oligothymidylate primers of various length]. I A Lokhova, G A Nevinskiĭ, N A Bulychev, V V Gorn, A S Levina, N K Rudenko, V M Kavsan, Olga I Lavrik Molekuliarnaia biologiia new
[Current acquisitions in antiviral drugs (anti-HIV)]. Erik De Clercq, Robert Snoeck Journal de pharmacie de Belgique pols set
The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability. S Sharma, CM Helchowski, CE Canman Mutation research topics set
Changes in DNA polymerases alpha, beta and gamma in mouse liver as a function of age. Fumio Hanaoka, J Sayato, H Arai, N Hasegawa, N Inui, Y Mitsui, Masami Yamada Mechanisms of ageing and development new
Interactions between human immunodeficiency virus type 1 reverse transcriptase, tRNA primer, and nucleocapsid protein during reverse transcription. M Hsu, Mark A. Wainberg Journal of human virology new
? new
? pols set
? new
Perspectives for the chemotherapy of AIDS. Erik De Clercq Anticancer research pols set
Cotransfection of mutated forms of human immunodeficiency virus type 1 Gag-Pol with wild-type constructs can interfere with processing and viral replication. N Morin, E Cherry, Xincang Li, Mark A. Wainberg Journal of human virology new
? new
? new
Antiviral activity and resistance profile of phosphazid--a novel prodrug of AZT. J Machado, H Salomon, Maureen Oliveira, C Tsoukas, A A Krayevsky, Mark A. Wainberg Nucleosides & nucleotides new
On the detection of multiple-binding modes of ligands to proteins, from biological, structural, and modeling data. Paul J Lewi, Marc R De Jonge, Frits F D Daeyaert, Luc Koymans, Maarten H Vinkers, Jan Heeres, Paul A J Janssen, Edward Arnold, Kalyan Das, Art D Clark, Stephen H Hughes, Paul L Boyer, Marie-Pierre P De Béthune, Rudi Pauwels, Koen Andries, Michael Kukla, Donald W Ludovici, Bart De Corte, Robert W Kavash, Chih Y Ho, Paul J Lewis Journal of computer-aided molecular design pols set
Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination. Sherine S L Chan, Janine H Santos, Joel N Meyer, Bhaskar S Mandavilli, Dennis L Cook, Consuelo L McCash, Grace E Kissling, Abraham Nyska, Julie F Foley, Bennett Van Houten, William C Copeland, Vernon E Walker, Kristine L Witt, Jack B Bishop Environmental and molecular mutagenesis pols set
? new
? new
? new
[Antiviral strategies in the replication of human immunodeficiency virus]. Mark A. Wainberg, S Bour, R Geleziunas, Z Bentwich L'unión médicale du Canada pols set
Cloning and expression of gene 2, required for the protein-primed initiation of the Bacillus subtilis phage phi 29 DNA replication. Luis Blanco, J A García, Margarita Salas Gene new
New developments in anti-HIV chemotherapy. Erik De Clercq Farmaco (Società chimica italiana : 1989) pols set
[Quantitative parameters of the 3'-5'-exonuclease reaction of human apurinic/apyrimidinic endonuclease 1 and DNA with single-strand breaks containing dYMP or their modified analogues]. Nadezhda S Dyrkheeva, Svetlana N Khodyreva, Olga I Lavrik Bioorganicheskaia khimiia new
? new
? new
Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. G T Tan, J M Pezzuto, A D Kinghorn, Stephen H Hughes Journal of natural products pols set
? new
? new
? new
[DNA polymerases beta and lambda, and their roles in the DNA replication and repair]. Ekaterina A Belousova, Olga I Lavrik Molekuliarnaia biologiia new
? new
? new
? new
? new
Telomerase activity in thyroid neoplasms evaluated by the expression of human telomerase reverse transcriptase (hTERT). Yasuhiro Ito, Hiroshi Yoshida, Chisato Tomoda, Takashi Uruno, Yuuki Takamura, Akihiro Miya, Kaoru Kobayashi, Fumio Matsuzuka, Kanji Kuma, Akira Miyauchi Anticancer research new
? new
? new
? new
Application of the C4'-alkylated deoxyribose primer system (CAPS) in allele-specific real-time PCR for increased selectivity in discrimination of single nucleotide sequence variants. Björn Tews, Jochen Wilhelm, Daniel Summerer, Michael Strerath, Andreas Marx, Peter Friedhoff, Alfred Pingoud, Meinhard Hahn Biological chemistry new
? new
Structural determinants of HIV-1 reverse transcriptase stereoselectivity towards (beta)-L-deoxy- and dideoxy-pyrimidine nucleoside triphosphates: molecular basis for the combination of L-dideoxynucleoside analogs with non-nucleoside inhibitors in anti HIV chemotherapy. Giovanni Maga, Mario Amacker, Ulrich Hübscher, G Gosselin, J L Imbach, C Mathé, A Faraj, J P Sommadossi, Silvio Spadari Nucleosides & nucleotides pols set
? new
? new
? new
Evolution and degeneration of eukaryotic DNA replication system. Masaharu Takemura Bio Systems new
Structure-based pharmacophore identification of new chemical scaffolds as non-nucleoside reverse transcriptase inhibitors. Maria Letizia Barreca, Laura De Luca, Nunzio Iraci, Angela Rao, Stefania Ferro, Giovanni Maga, Alba Chimirri Journal of chemical information and modeling pols set
? new
? new
? new
? new
? new
? new
? new
? new
? new
? new
? new
The nature of the DNA substrate influences pre-catalytic conformational changes of DNA polymerase β. J Huang, KS Alnajjar, MM Mahmoud, BE Eckenroth, S Doublie, J Sweasy The Journal of biological chemistry 2018 topics set
Switching between Exonucleolysis and Replication by T7 DNA Polymerase Ensures High Fidelity. TP Hoekstra, M Depken, SN Lin, J Cabanas-Danés, P Gross, RT Dame, EJ Peterman, GJ Wuite Biophysical journal 2017 topics set
DNA polymerase 3'→5' exonuclease activity: Different roles of the beta hairpin structure in family-B DNA polymerases. Hariyanto Darmawan, Melissa Harrison, Linda J Reha-Krantz DNA repair 2015 new
Mitochondrial Single-stranded DNA-binding Proteins Stimulate the Activity of DNA Polymerase γ by Organization of the Template DNA. Grzegorz L Ciesielski, Oya Bermek, Fernando A Rosado-Ruiz, Stacy L Hovde, Orrin J Neitzke, Jack D Griffith, Laurie S Kaguni The Journal of biological chemistry 2015 topics set
Real-time single-molecule studies of the motions of DNA polymerase fingers illuminate DNA synthesis mechanisms. Geraint W Evans, Johannes Hohlbein, Timothy D Craggs, Louise Aigrain, Achillefs N Kapanidis Nucleic acids research 2015 topics set
Highly efficient one-step PCR-based mutagenesis technique for large plasmids using high-fidelity DNA polymerase. H Liu, R Ye, Y Y Wang Genetics and molecular research : GMR 2015 new
PIP degron proteins, substrates of CRL4Cdt2, and not PIP boxes, interfere with DNA polymerase η and κ focus formation on UV damage. Nikolay Tsanov, Chames Kermi, Philippe Coulombe, Siem van der Laan, Dana Hodroj, Domenico Maiorano Nucleic acids research 2014 new
Enhancing the processivity of a family B-type DNA polymerase of Thermococcus onnurineus and application to long PCR. Yun Jae Kim, Hyun Sook Lee, Suk-Tae Kwon, Jung-Hyun Lee, Sung Gyun Kang Biotechnology letters 2014 new
A hot start alternative for high-fidelity DNA polymerase amplification mediated by quantum dots. Fuming Sang, Yang Yang, Ying Lin, Zhizhou Zhang Acta biochimica et biophysica Sinica 2014 new
Crystal structure of the vaccinia virus DNA polymerase holoenzyme subunit D4 in complex with the A20 N-terminal domain. Céline Contesto-Richefeu, Nicolas Tarbouriech, Xavier Brazzolotto, Stéphane Betzi, Xavier Morelli, Wim P Burmeister, Frédéric Iseni PLoS pathogens 2014 new
Identification of paired immunoglobulin-like type 2 receptor α as hepatitis B virus DNA polymerase transactivated protein 1 interacting proteins. Yong-Zhi Lun, Qing Chi, Xue-Lei Wang, Fang Wang, Wen Sui Molecular medicine reports 2014 new
Sustained active site rigidity during synthesis by human DNA polymerase μ. Andrea F Moon, John M Pryor, Dale A Ramsden, Thomas A Kunkel, Katarzyna Bebenek, Lars C Pedersen Nature structural & molecular biology 2014 new
Nucleotide selection by the Y-family DNA polymerase Dpo4 involves template translocation and misalignment. Alfonso Brenlla, Radoslaw P Markiewicz, David Rueda, Louis J Romano Nucleic acids research 2014 new
DNA polymerase preference determines PCR priming efficiency. Wenjing Pan, Miranda Byrne-Steele, Chunlin Wang, Stanley Lu, Scott Clemmons, Robert J Zahorchak, Jian Han BMC biotechnology 2014 new
DNA polymerase as a molecular motor and pump. Samudra Sengupta, Michelle M Spiering, Krishna K Dey, Wentao Duan, Debabrata Patra, Peter J Butler, R Dean Astumian, Stephen J Benkovic, Ayusman Sen ACS nano 2014 new
The stability of Taq DNA polymerase results from a reduced entropic folding penalty; identification of other thermophilic proteins with similar folding thermodynamics. Chin-Chi Liu, Vince J LiCata Proteins 2014 new
Fluorescence resonance energy transfer studies of DNA polymerase β: the critical role of fingers domain movements and a novel non-covalent step during nucleotide selection. Jamie B Towle-Weicksel, Shibani Dalal, Christal D Sohl, Sylvie Doublié, Karen S Anderson, Joann B Sweasy The Journal of biological chemistry 2014 new
Structural basis for processive DNA synthesis by yeast DNA polymerase ɛ. M Hogg, Pia Osterman, Göran O Bylund, Rais A Ganai, Else-Britt Lundström, AE Sauer-Eriksson, Erik Johansson Nature structural & molecular biology 2014 topics set
A novel approach for rapid detection of bacterially contaminated platelet concentrates via sensitive measurement of microbial DNA polymerase activity. Daniel R Zweitzig, Nichol M Riccardello, John M Pester, Rebecca Jeanmonod, Mark J Kopnitsky, S Mark O'Hara Transfusion 2014 new
Look Ma, no PCNA: how DNA polymerase ε synthesizes long stretches of DNA without a processivity factor. Karl E Zahn, Sylvie Doublié Nature structural & molecular biology 2014 new
Kinetics, structure, and mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine bypass by human DNA polymerase η. Amritraj Patra, Leslie D Nagy, Qianqian Zhang, Yan Su, Livia Müller, F Peter Guengerich, Martin Egli The Journal of biological chemistry 2014 new
A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome. Aline C Simon, Jin C Zhou, Rajika L Perera, Frederick van Deursen, Cecile Evrin, Marina E Ivanova, Mairi L Kilkenny, Ludovic Renault, Svend Kjaer, Dijana Matak-Vinković, Karim Labib, Alessandro Costa, Luca Pellegrini Nature 2014 new
In vivo evidence that phenylalanine 171 acts as a molecular brake for translesion DNA synthesis across benzo[a]pyrene DNA adducts by human DNA polymerase κ. Akira Sassa, Tetsuya Suzuki, Yuki Kanemaru, Naoko Niimi, Hirofumi Fujimoto, Atsushi Katafuchi, Petr Grúz, Manabu Yasui, Ramesh C Gupta, Francis Johnson, Toshihiro Ohta, Masamitsu Honma, Noritaka Adachi, Takehiko Nohmi DNA repair 2014 new
Functional analysis of Drosophila DNA polymerase ε p58 subunit. Ritsuko Sahashi, Risa Matsuda, Osamu Suyari, Mieko Kawai, Hideki Yoshida, Sue Cotterill, Masamitsu Yamaguchi American journal of cancer research 2013 topics set
A novel function of CRL4Cdt2: regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phase. Sufang Zhang, Hong Zhao, Zbiegniew Darzynkiewicz, Pengbo Zhou, Zhongtao Zhang, Ernest Y C Lee, Marietta Y W T Lee The Journal of biological chemistry 2013 topics set
Towards new C6-rigid S-DABO HIV-1 reverse transcriptase inhibitors: Synthesis, biological investigation and molecular modeling studies. Hai-Qiu Wu, Zi-Hong Yan, Wen-Xue Chen, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Dirk Daelemans, Christophe Pannecouque Bioorganic & medicinal chemistry 2013 topics set
Telomeres-structure, function, and regulation. Weisi Lu, Yongqing Zhang, Dan Liu, Zhou Songyang, Ma Wan Experimental cell research 2013 new
Expression and mechanism of PinX1 and telomerase activity in the carcinogenesis of esophageal epithelial cells. Jing Zuo, Da-Hu Wang, Yu-Jun Zhang, Liang Liu, Feng-Ling Liu, Wei Liu Oncology reports 2013 topics set
Targeting of the Purine Biosynthesis Host Cell Pathway Enhances the Activity of Tenofovir Against Sensitive and Drug-Resistant HIV-1. A Heredia, CE Davis, MS Reitz, NM Le, MA Wainberg, JS Foulke, LX Wang, RR Redfield The Journal of infectious diseases 2013 topics set
DNA polymerases are error-prone at RecA-mediated recombination intermediates. Richard T Pomerantz, Myron F Goodman, Michael E O'Donnell Cell cycle (Georgetown, Tex.) 2013 topics set
Proofreading exonuclease on a tether: the complex between the E. coli DNA polymerase III subunits α, epsilon, θ and β reveals a highly flexible arrangement of the proofreading domain. Kiyoshi Ozawa, NP Horan, A Robinson, H Yagi, FR Hill, Slobodan Jergic, ZQ Xu, KV Loscha, N Li, M Tehei, Aaron J Oakley, Gottfried Otting, T Huber, Nicholas E Dixon Nucleic acids research 2013 topics set
Nuclear transport of Epstein-Barr virus DNA polymerase is dependent on the BMRF1 polymerase processivity factor and molecular chaperone Hsp90. Daisuke Kawashima, Teru Kanda, Takayuki Murata, Shinichi Saito, Atsuko Sugimoto, Yohei Narita, Tatsuya Tsurumi Journal of virology 2013 pols set
Emergence of DNA polymerase ε antimutators that escape error-induced extinction in yeast. Lindsey N Williams, Alan J Herr, Bradley D Preston Genetics 2013 pols set
Interaction between DNA Polymerase β and BRCA1. Aya Masaoka, Natalie R Gassman, Julie K Horton, Padmini S Kedar, Kristine L Witt, Cheryl A Hobbs, Grace E Kissling, Keizo Tano, Kenjiro Asagoshi, Samuel H Wilson PloS one 2013 topics set
Leukotriene biosynthesis inhibitor MK886 impedes DNA polymerase activity. Amit Ketkar, Maroof Khan Zafar, Leena Maddukuri, Kinrin Yamanaka, Surajit Banerjee, Martin Egli, Jeong-Yun Choi, R Stephen Lloyd, Robert Lawton Eoff Chemical research in toxicology 2013 topics set
Evolving uses of oral reverse transcriptase inhibitors in the HIV-1 epidemic: from treatment to prevention. Ravindra K Gupta, DA Van de Vijver, S Manicklal, MA Wainberg Retrovirology 2013 pols set
Observing a DNA polymerase choose right from wrong. Bret D Freudenthal, William A Beard, David D Shock, Samuel H Wilson Cell 2013 topics set
Understanding the loss-of-function in a triple missense mutant of DNA polymerase β found in prostate cancer. Changlong An, William A Beard, D Chen, Samuel H Wilson, NM Makridakis International journal of oncology 2013 pols set
Structural model of the Y-Family DNA polymerase V/RecA mutasome. Sushil Chandani, Edward L Loechler Journal of molecular graphics & modelling 2013 topics set
Involvement of the reparative DNA polymerase pol X of African swine fever virus in the maintenance of viral genome stability in vivo. Modesto Redrejo-Rodríguez, Javier M Rodríguez, Cristina Suárez, José Salas, María L Salas Journal of virology 2013 pols set
Inhibitory effects of α-mangostin on mammalian DNA polymerase, topoisomerase, and human cancer cell proliferation. Yoshiyuki Mizushina, Isoko Kuriyama, Tatsuo Nakahara, Yoshihito Kawashima, Hiromi Yoshida Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 topics set
Ring-opening of the γ-OH-PdG adduct promotes error-free bypass by the Sulfolobus solfataricus DNA polymerase Dpo4. Ganesh Shanmugam, Irina G Minko, Surajit Banerjee, Plamen P Christov, Ivan D Kozekov, Carmelo J Rizzo, R Stephen Lloyd, Martin Egli, Michael P Stone Chemical research in toxicology 2013 new
Muscle-specific overexpression of the catalytic subunit of DNA polymerase γ induces pupal lethality in Drosophila melanogaster. Francisco Martínez-Azorín, Manuel Calleja, Rosana Hernández-Sierra, Carol L Farr, Laurie S Kaguni, Rafael Garesse Archives of insect biochemistry and physiology 2013 topics set
Dancing with chemical formulae of antivirals: a personal account. Erik De Clercq Biochemical pharmacology 2013 new
Following DNA Chain Extension and Protein Conformational Changes in Crystals of a Y-Family DNA Polymerase via Raman Crystallography. Shirly J Espinoza-Herrera, Vineet Gaur, Zucai Suo, Paul R Carey Biochemistry 2013 topics set
Extension into the entrance channel of HIV-1 reverse transcriptase-Crystallography and enhanced solubility. Mariela Bollini, Kathleen M Frey, José A Cisneros, Krasimir A Spasov, Kalyan Das, Joseph David Bauman, Edward Arnold, Karen S Anderson, William L Jorgensen Bioorganic & medicinal chemistry letters 2013 topics set
Yeast pol4 promotes tel1-regulated chromosomal translocations. José F Ruiz, Benjamin Pardo, Guillermo Sastre-Moreno, Andrés Aguilera, Luis Blanco PLoS genetics 2013 pols set
Basis for the Early and Preferential Selection of the E138K Substitution in HIV-1 Reverse Transcriptase with Etravirine. Matthew McCallum, Maureen Oliveira, Ruxandra-Ilinca Ibanescu, Victor G Kramer, Daniela D Moisi, Eugene L Asahchop, Bluma G Brenner, Richard Harrigan, Hongtao Xu, Mark A. Wainberg Antimicrobial agents and chemotherapy 2013 pols set
dNTP-dependent conformational transitions in the fingers subdomain of Klentaq1 DNA polymerase: insights into the role of the "nucleotide-binding" state. Paul J Rothwell, William J Allen, Evangelos Sisamakis, Stanislav Kalinin, Suren Felekyan, Jerker Widengren, Gabriel Waksman, Claus A M Seidel The Journal of biological chemistry 2013 pols set
Development of noninvasive prenatal diagnosis of trisomy 21 by RT-MLPA with a new set of SNP markers. Pei-Qiong Li, Jun Zhang, Jian-Hui Fan, Yuan-Zhi Zhang, Hong-Ying Hou Archives of gynecology and obstetrics 2013 complete Hong-Ying Hou*
Inhibitory effects of low molecular weight polyphenolics from Inonotus obliquus on human DNA topoisomerase activity and cancer cell proliferation. Isoko Kuriyama, Yuki Nakajima, Hiroshi Nishida, Tetsuya Konishi, Toshifumi Takeuchi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Molecular medicine reports 2013 new
Insights into the Conformation of Aminofluorene-dG Adduct in a DNA Polymerase Active Site. Vaidya Ganessan Vaidyanathan, Fengting Liang, William A Beard, David D Shock, Samuel H Wilson, Bongsup P Cho The Journal of biological chemistry 2013 pols set
Mechanism for priming DNA synthesis by yeast DNA Polymerase α. Rajika L Perera, R Torella, Sebastian Klinge, Mairi L Kilkenny, JD Maman, Luca Pellegrini eLife 2013 topics set
Distinctive effects of domain deletions on the manganese-dependent DNA polymerase and DNA phosphorylase activities of Mycobacterium smegmatis polynucleotide phosphorylase. Mihaela-Carmen Unciuleac, Stewart Shuman Biochemistry 2013 pols set
Hepatocytes transduced with human TERT gene acquire a prolonged lifespan in culture and retain permissiveness to hepatitis B virus. L P Lv, Y L Kong, F Yan, P Ma, X P Zhou, Y Y Zhang, D Q Wen, X L Yu, H Y Zhang, H Zhou, J B Xu Acta virologica 2013 topics set
Hypersusceptibility mechanism of Tenofovir-resistant HIV to EFdA. Eleftherios Michailidis, Emily M Ryan, Atsuko Hachiya, Karen A Kirby, Bruno Marchand, Maxwell D Leslie, Andrew D Huber, Yee Tsuey Ong, Jacob C Jackson, Kamalendra Singh, Eiichi N Kodama, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos Retrovirology 2013 pols set
DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation. Rémy Bétous, Marie-Jeanne Pillaire, Laura Pierini, Siem van der Laan, Bénédicte Recolin, Emma Ohl-Séguy, Caixia Guo, Naoko Niimi, Petr Grúz, Takehiko Nohmi, Errol C Friedberg, Christophe Cazaux, Domenico Maiorano, Jean-Sébastien Hoffmann The EMBO journal 2013 new
Novel inhibition of archaeal family-D DNA polymerase by uracil. Tomas T Richardson, Louise Gilroy, Yoshizumi Ishino, Bernard A Connolly, Ghislaine Henneke Nucleic acids research 2013 new
DNA polymerase POLQ and cellular defense against DNA damage. Matthew J Yousefzadeh, Richard D Wood DNA repair 2013 new
Design, Synthesis, and Evaluation of WC5 Analogues as Inhibitors of Human Cytomegalovirus Immediate-Early 2 Protein, a Promising Target for Anti-HCMV Treatment. Serena Massari, Beatrice Mercorelli, Luca Sancineto, Stefano Sabatini, Violetta Cecchetti, Giorgio Gribaudo, Giorgio Palù, Christophe Pannecouque, Arianna Loregian, Oriana Tabarrini ChemMedChem 2013 topics set
The preferential selection of K65R in HIV-1 subtype C is attenuated by nucleotide polymorphisms at thymidine analogue mutation sites. Cédric F Invernizzi, Dimitrios Coutsinos, Maureen Oliveira, Rita S Schildknecht, Hongtao Xu, Simani Gaseitswe, Daniela D Moisi, Bluma G Brenner, Mark A. Wainberg The Journal of antimicrobial chemotherapy 2013 pols set
The REV7 subunit of DNA polymerase ζ is essential for primordial germ cell maintenance in the mouse. Naoki Watanabe, Shinji Mii, Naoya Asai, Masato Asai, Kaoru Niimi, Kaori Ushida, Takuya Kato, Atsushi Enomoto, Hideshi Ishii, Masahide Takahashi, Yoshiki Murakumo The Journal of biological chemistry 2013 new
Mutations in HIV-1 reverse transcriptase cause misfolding and miscleavage by the viral protease. Linda L Dunn, Paul L Boyer, Patrick K Clark, Stephen H Hughes Virology 2013 pols set
[Effect of Mn(II) on the error-prone DNA polymerase iota activity in extracts from human normal and tumor cells]. A V Lakhin, A S Efremova, Irina V Makarova, E E Grishina, S I Shram, Vyacheslav Z Tarantul, Leonid V Gening Molekuliarnaia genetika, mikrobiologiia i virusologiia 2013 topics set
Evolution of HIV integrase resistance mutations. Peter K Quashie, Thibault Mesplède, Mark A. Wainberg Current opinion in infectious diseases 2013 new
Alteration in the cavity size adjacent to the active site of RB69 DNA polymerase changes its conformational dynamics. Shuangluo Xia, Marcus Wood, Michael J Bradley, Enrique M De La Cruz, William H Konigsberg Nucleic acids research 2013 topics set
A plasmid-based lacZα gene assay for DNA polymerase fidelity measurement. Brian J Keith, Stanislaw K Jozwiakowski, Bernard A Connolly Analytical biochemistry 2013 complete Brad Langhorst
Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses. Julie K Horton, Donna F Stefanick, Natalie R Gassman, Jason G Williams, Scott A Gabel, Matthew J Cuneo, Rajendra Prasad, Padmini S Kedar, Eugene F DeRose, Esther W Hou, Robert E London, Samuel H Wilson DNA repair 2013 new
Cycloartenyl trans-ferulate, a component of the bran byproduct of sake-brewing rice, inhibits mammalian DNA polymerase and suppresses inflammation. Yoshiyuki Mizushina, Isoko Kuriyama, Asahi Yamazaki, Takahiro Akashi, Hiromi Yoshida Food chemistry 2013 new
An in-frame deletion at the polymerase active site of POLD1 causes a multisystem disorder with lipodystrophy. Michael N Weedon, Sian Ellard, Marc J Prindle, Richard Caswell, Hana Lango Allen, Richard Oram, Koumudi Godbole, Chittaranjan S Yajnik, Paolo Sbraccia, Giuseppe Novelli, Peter Turnpenny, Emma McCann, Kim Jee Goh, Yukai Wang, Jonathan Fulford, Laura J McCulloch, David B Savage, Stephen O'Rahilly, Katarina Kos, Lawrence A Loeb, Robert K Semple, Andrew T Hattersley Nature genetics 2013 new
A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli. Amit Sharma, J Kottur, N Narayanan, Deepak T Nair Nucleic acids research 2013 pols set
A single-molecule approach to DNA replication in Escherichia coli cells demonstrated that DNA polymerase III is a major determinant of fork speed. Tuan Minh Pham, Kang Wei Tan, Yuichi Sakumura, Katsuzumi Okumura, Hisaji Maki, Masahiro Tatsumi Akiyama Molecular microbiology 2013 new
Fidelity, mismatch extension, and proofreading activity of the Plasmodium falciparum apicoplast DNA polymerase. Bentley M Wingert, Eric E Parrott, Scott W Nelson Biochemistry 2013 new
Histone Lysine-Specific Methyltransferases and Demethylases in Carcinogenesis: New Targets for Cancer Therapy and Prevention. Xuejiao Tian, Saiyang Zhang, Hong-Min Liu, Yan-Bing Zhang, Christopher A Blair, Dan Mercola, Paolo Sassone-Corsi, Xiaolin Zi Current cancer drug targets 2013 topics set
Rapid detection of orf virus by loop-mediated isothermal amplification based on the DNA polymerase gene. Jinming Li, Deguang Song, Wenqi He, Yingfu Bao, Rongguang Lu, Gaoli Su, Gaili Wang, Huijun Lu, Kui Zhao, Feng Gao Archives of virology 2013 topics set
Preferential D-loop extension by a translesion DNA polymerase underlies error-prone recombination. Richard T Pomerantz, Isabel Kurth, Myron F Goodman, Mike E O'Donnell Nature structural & molecular biology 2013 topics set
Dual inhibition of DNA polymerase PolC and protein tyrosine phosphatase CpsB uncovers a novel antibiotic target. Alistair J Standish, Angela A Salim, Robert J Capon, Renato Morona Biochemical and biophysical research communications 2013 topics set
Involvement of AtPolλ in repair of high salt and DNA cross linking agent induced double strand breaks in Arabidopsis thaliana. Sujit Roy, Swarup Roy Choudhury, Dibyendu Narayan SenGupta, Kali Pada Das Plant physiology 2013 pols set
A structural role for the PHP domain in E. coli DNA polymerase III. Tiago Barros, Joel Guenther, Brian A Kelch, Jordan Anaya, Arjun Prabhakar, Mike E O'Donnell, John Kuriyan, Meindert H Lamers BMC structural biology 2013 new
The UmuC subunit of the E. coli DNA polymerase V shows a unique interaction with the β-clamp processivity factor. Atif A Patoli, Jody A Winter, Karen A Bunting BMC structural biology 2013 new
Molecular design, synthesis and biological evaluation of BP-O-DAPY and O-DAPY derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors. Shiqiong Yang, Christophe Pannecouque, Dirk Daelemans, Xiao-Dong Ma, Yang Liu, Fen-Er Chen, Erik De Clercq European journal of medicinal chemistry 2013 pols set
Herpes simplex virus 1 DNA polymerase processivity factor UL42 inhibits TNF-α-induced NF-κB activation by interacting with p65/RelA and p50/NF-κB1. Jie Zhang, Shuai Wang, Kezhen Wang, Chunfu Zheng Medical microbiology and immunology 2013 new
Spectroscopic analysis of polymerization and exonuclease proofreading by a high-fidelity DNA polymerase during translesion DNA synthesis. Babho Devadoss, Irene Lee, Anthony J Berdis Biochimica et biophysica acta 2013 topics set
Structural changes in the hydrophobic hinge region adversely affect the activity and fidelity of the I260Q mutator of DNA polymerase ß Chelsea L Gridley, Sneha Rangarajan, Susan J Firbank, Shibani Dalal, Joann B Sweasy, Joachim Jaeger Biochemistry 2013 topics set
The excision of 3' penultimate errors by DNA polymerase I and its role in endonuclease V-mediated DNA repair. Chia-Chia Lee, Ya-Chien Yang, Steven D Goodman, Chien-Ju Lin, Yi-An Chen, Yi-Ting Wang, Wern-Cherng Cheng, Liang-In Lin, Woei-Horng Fang DNA repair 2013 new
Discovery of Piperidine-Linked Pyridine Analogues as Potent Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors. Xuwang Chen, Yuanyuan Li, Shufang Ding, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Huiqing Liu, Xinyong Liu ChemMedChem 2013 topics set
Amino acid substitution in the active site of DNA polymerase β explains the energy barrier of the nucleotidyl transfer reaction. Vinod K Batra, Lalith Perera, Ping Lin, David D Shock, William A Beard, Lars C Pedersen, Lee G Pedersen, Samuel H Wilson Journal of the American Chemical Society 2013 topics set
The Human Tim/Tipin Complex Directly Interacts with DNA Polymerase {epsilon} and Stimulates its Synthetic Activity. Valentina Aria, Mariarita De Felice, Roberta Di Perna, Shuji Uno, Hisao Masai, Juhani E Syvaoja, Barbara van Loon, Ulrich Hubscher, Francesca M Pisani The Journal of biological chemistry 2013 topics set
A non-catalytic role of DNA polymerase η in recruiting Rad18 and promoting PCNA monoubiquitination at stalled replication forks. Michael Durando, Satoshi Tateishi, Cyrus Vaziri Nucleic acids research 2013 topics set
RecA acts as a switch to regulate polymerase occupancy in a moving replication fork. Chiara Indiani, Meghna Patel, Myron F Goodman, Mike E O'Donnell Proceedings of the National Academy of Sciences of the United States of America 2013 topics set
Dual role for mammalian DNA polymerase ζ in maintaining genome stability and proliferative responses. Sabine S Lange, Ella Bedford, Shelley Reh, John P Wittschieben, Steve Carbajal, Donna F Kusewitt, John DiGiovanni, Richard D Wood Proceedings of the National Academy of Sciences of the United States of America 2013 topics set
Improving bioorthogonal protein ubiquitylation by click reaction. Daniel Schneider, Tatjana Schneider, Daniel Rösner, Martin Scheffner, Andreas Marx Bioorganic & medicinal chemistry 2013 new
HIV-1 reverse transcriptase and antiviral drug resistance. Part 2. Kalyan Das, Edward Arnold Current opinion in virology 2013 topics set
The Exonuclease Activity of the Yeast Mitochondrial DNA Polymerase γ Suppresses Mitochondrial DNA Deletions Between Short Direct Repeats in Saccharomyces cerevisiae. Jeffrey D Stumpf, William C Copeland Genetics 2013 topics set
NMR mapping of PCNA interaction with translesion synthesis DNA polymerase Rev1 mediated by Rev1-BRCT domain. Yulia Pustovalova, Mark W Maciejewski, Dmitry M Korzhnev Journal of molecular biology 2013 new
Replication of a carcinogenic nitropyrene DNA lesion by human Y-family DNA polymerase. Kevin N Kirouac, Ashis K Basu, Hong Ling Nucleic acids research 2013 topics set
Optimization of the masking molecule for active-site-protected immobilization of Taq DNA polymerase and its application. Gumjung Lim, Joungmok Kim, Jeong Hee Kim Analytical biochemistry 2013 topics set
Trinucleotide repeat deletion via a unique hairpin bypass by DNA polymerase β and alternate flap cleavage by flap endonuclease 1. Meng Xu, Jonathan Gabison, Yuan Liu Nucleic acids research 2013 topics set
DNA polymerase β promoter mutations and transcriptional activity in esophageal squamous cell carcinoma. Min Li, Wenqiao Zang, Yuanyuan Wang, Yuebai Li, Yunyun Ma, Na Wang, Yue Tang, Lulu Liu, Ziming Dong, Guoqiang Zhao Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2013 new
HIV-1 reverse transcriptase and antiviral drug resistance. Part 1. Kalyan Das, Edward Arnold Current opinion in virology 2013 topics set
Ribonucleotides Are Signals for Mismatch Repair of Leading-Strand Replication Errors. Scott A Lujan, Jessica S Williams, Anders R Clausen, Alan B Clark, Thomas A Kunkel Molecular cell 2013 topics set
Replication-competent infectious hepatitis B virus vectors carrying substantially sized transgenes by redesigned viral polymerase translation. Zihua Wang, Li Wu, Xin Cheng, Shizhu Liu, Baosheng Li, Haijun Li, Fubiao Kang, Junping Wang, Huan Xia, Caiyan Ping, Michael Nassal, Dianxing Sun PloS one 2013 complete Dianxing Sun*
Competitive Fitness during Feast and Famine: How SOS DNA Polymerases Influence Physiology and Evolution in Escherichia coli. Christopher H Corzett, Myron F Goodman, Steven E Finkel Genetics 2013 pols set
PolA1, a putative DNA polymerase I, is coexpressed with PerR and contributes to peroxide stress defenses of group A Streptococcus. Chadia Toukoki, Ioannis Gryllos Journal of bacteriology 2013 topics set
Inhibitory effects of myricetin on mammalian DNA polymerase, topoisomerase and human cancer cell proliferation. Kazuaki Shiomi, Isoko Kuriyama, Hiromi Yoshida, Yoshiyuki Mizushina Food chemistry 2013 topics set
Translesion synthesis past acrolein-derived DNA adducts by human mitochondrial DNA polymerase γ Rajesh Kasiviswanathan, Irina G Minko, R Stephen Lloyd, William C Copeland The Journal of biological chemistry 2013 topics set
Mechanism of somatic hypermutation at the WA motif by human DNA polymerase η Yaofeng Zhao, Mark T Gregory, Christian Biertümpfel, Yue-Jin Hua, Fumio Hanaoka, Wei Wen Yang Proceedings of the National Academy of Sciences of the United States of America 2013 topics set
Mouse DNA polymerase kappa has a functional role in the repair of DNA strand breaks. Xiuli Zhang, Lingna Lv, Qian Chen, Fenghua Yuan, Ting Zhang, Yeran Yang, Hui Zhang, Yun Wang, Yan Jia, Liangyue Qian, Benjamin Chen, Yongqing Zhang, Errol C Friedberg, Tie-Shan Tang, Caixia Guo DNA repair 2013 pols set
Reconstitution of recombination-associated DNA synthesis with human proteins. Jessica L Sneeden, Sara M Grossi, Inger Tappin, Jerard Hurwitz, Wolf-Dietrich Heyer Nucleic acids research 2013 pols set
Clinical and Molecular Features of POLG-Related Mitochondrial Disease. Jeffrey D Stumpf, Russell P Saneto, William C Copeland Cold Spring Harbor perspectives in biology 2013 pols set
A solution to release twisted DNA during chromosome replication by coupled DNA polymerases. Isabel Kurth, Roxana E Georgescu, Mike E O'Donnell Nature 2013 new
Restriction fragment mass polymorphism (RFMP) analysis based on MALDI-TOF mass spectrometry for detecting antiretroviral resistance in HIV-1 infected patients. J-H Lee, Atsuko Hachiya, S-K Shin, J Lee, Hiroyuki Gatanaga, Shinichi Oka, Karen A Kirby, Yee Tsuey Ong, Stefan G Sarafianos, William R Folk, Wangdon Yoo, Sun Pyo Hong, S-O Kim Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2013 pols set
Conformational landscapes of DNA polymerase I and mutator derivatives establish fidelity checkpoints for nucleotide insertion. Johannes Hohlbein, Louise Aigrain, Timothy D Craggs, Oya Bermek, Olga Potapova, Pouya Shoolizadeh, Nigel D F Grindley, Catherine M Joyce, Achillefs N Kapanidis Nature communications 2013 new
A high-throughput and quantitative method to assess the mutagenic potential of translesion DNA synthesis. DJ Taggart, Terry L Camerlengo, Jason K Harrison, Shanen M Sherrer, Ajay K Kshetry, John-Stephen Taylor, Kun Huang, Zucai Suo Nucleic acids research 2013 topics set
Single-Molecule Investigation of Substrate Binding Kinetics and Protein Conformational Dynamics of a B-Family Replicative DNA Polymerase. Brian A Maxwell, Zucai Suo The Journal of biological chemistry 2013 new
Structure and functional analysis of the BRCT domain of translesion synthesis DNA polymerase Rev1. John M Pryor, Lokesh Gakhar, M Todd Washington Biochemistry 2013 new
DNA synthesis by Pol η promotes fragile site stability by preventing under-replicated DNA in mitosis. Valérie Bergoglio, Anne-Sophie Boyer, Erin Walsh, Valeria Naim, Gaëlle Legube, Marietta Y W T Lee, Laurie Rey, Filippo Rosselli, Christophe Cazaux, Kristin A Eckert, Jean-Sébastien Hoffmann The Journal of cell biology 2013 new
Impact of macromolecular crowding on DNA replication. Barak Akabayov, Sabine R Akabayov, Seung-Joo Lee, Gerhard Wagner, Charles C Richardson Nature communications 2013 pols set
Pin1 interacts with the Epstein-Barr virus DNA polymerase catalytic subunit and regulates viral DNA replication. Yohei Narita, Takayuki Murata, Akihide Ryo, Daisuke Kawashima, Atsuko Sugimoto, Teru Kanda, Hiroshi Kimura, Tatsuya Tsurumi Journal of virology 2013 pols set
Fast mitochondrial DNA isolation from mammalian cells for next-generation sequencing. Wilber Quispe-Tintaya, Ryan R White, Vasily N Popov, Jan Vijg, Alexander Y Maslov BioTechniques 2013 topics set
Circulating tumor cells as a surrogate marker for determining clinical outcome to mFOLFOX chemotherapy in patients with stage III colon cancer. C-Y Lu, H-L Tsai, Y-H Uen, H-M Hu, C-W Chen, T-L Cheng, S-R Lin, J-Y Wang British journal of cancer 2013 new
Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase. Daniel G Kuroda, Joseph David Bauman, J Reddy Challa, Disha Patel, Thomas Troxler, Kalyan Das, Edward Arnold, Robin M Hochstrasser Nature chemistry 2013 pols set
Synthesis and biological evaluation of pyridazine derivatives as novel HIV-1 NNRTIs. Dongyue Li, Peng Zhan, Huiqing Liu, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu Bioorganic & medicinal chemistry 2013 pols set
Replicative DNA polymerases. Erik Johansson, Nicholas Dixon Cold Spring Harbor perspectives in biology 2013 new
Construction of shRNA expression plasmids for silkworm cell lines using single-stranded DNA and Bst DNA polymerase. Hiromitsu Tanaka Methods in molecular biology (Clifton, N.J.) 2013 pols set
Significant association of 5p15.33 (TERT-CLPTM1L genes) with lung cancer in Chinese Han population. Zhenhong Zhao, Cong Li, Lixin Yang, Xiaobo Zhang, Xueying Zhao, Xiao Song, Xiaoying Li, Jiucun Wang, Ji Qian, Yajun Yang, Li Jin, Hongyan Chen, Daru Lu Experimental lung research 2013 topics set
Systematic Functional Comparative Analysis of Four Single-Stranded DNA-Binding Proteins and Their Affection on Viral RNA Metabolism. Haiyan Shi, Yongqing Zhang, Guohui Zhang, Jinlei Guo, Xun Zhang, Haiyan Song, Jianxin Lv, Jimin Gao, Yuepeng Wang, Litian Chen, Yue Wang PloS one 2013 new
Interaction of PARP-2 with DNA structures mimicking DNA repair intermediates and consequences on activity of base excision repair proteins. Mikhail M Kutuzov, Svetlana N Khodyreva, Jean-Christophe Amé, Ekaterina S Ilina, Maria V Sukhanova, Valerie Schreiber, Olga I Lavrik Biochimie 2013 new
N(1),N(3)-disubstituted uracils as nonnucleoside inhibitors of HIV-1 reverse transcriptase. Mikhail S Novikov, Vladimir T Valuev-Elliston, Denis A Babkov, Maria P Paramonova, Alexander V Ivanov, Sergey A Gavryushov, Anastasia L Khandazhinskaya, Sergey N Kochetkov, Christophe Pannecouque, Graciela Andrei, Robert Snoeck, Jan Balzarini, Katherine L Seley-Radtke Bioorganic & medicinal chemistry 2013 pols set
The hepatitis B virus ribonuclease h is sensitive to inhibitors of the human immunodeficiency virus ribonuclease h and integrase enzymes. John E Tavis, Xiaohong Cheng, Yuan Hu, Michael Totten, Feng Cao, Eleftherios Michailidis, Rajeev Aurora, Marvin J Meyers, E Jon Jacobsen, Michael A. Parniak, Stefan G Sarafianos PLoS pathogens 2013 topics set
Detecting allosteric sites of HIV-1 reverse transcriptase by X-ray crystallographic fragment screening. Joseph David Bauman, Disha Patel, Chhaya Dharia, Marc Fromer, Sameer Ahmed, Yulia Volovik Frenkel, J Thomas Eck, William C Ho, Kalyan Das, Aaron J Shatkin, Edward Arnold Journal of medicinal chemistry 2013 pols set
Inhibition of repair-related DNA polymerases by vitamin Ks, their related quinone derivatives and associated inflammatory activity (Review). Yoshiyuki Mizushina, Shin Nishiumi, Masayuki Nishida, Hiromi Yoshida, Takeshi Azuma, Masaru Yoshida International journal of oncology 2013 new
Cellular roles of DNA polymerase beta. Sreerupa Ray, Miriam Rose Menezes, Alireza G Senejani, Joann B Sweasy The Yale journal of biology and medicine 2013 new
RNA pathogen detection with one-step reverse transcription PCR and strand-displacement based signal amplification. Feng Du, Frank Streckenbach, Haodong Chen, Xin Huang, Zhuo Tang, Andreas Marx The Analyst 2013 topics set
DNA Polymerase λ Inactivation by Oxidized Abasic Sites. Adam J Stevens, Lirui Guan, Katarzyna Bebenek, Thomas A Kunkel, Marc M Greenberg Biochemistry 2013 topics set
The Effect of Mutations at Position E138 in HIV-1 Reverse Transcriptase and their Interactions with the M184I Mutation in Defining Patterns of Resistance to the Non-Nucleoside Reverse Transcriptase Inhibitors Rilpivirine and Etravirine. Hong-Tao Xu, Susan P Colby-Germinario, Eugene L Asahchop, Maureen Oliveira, Matthew McCallum, Susan M Schader, Yingshan Han, Yudong Quan, Stefan G Sarafianos, Mark A. Wainberg Antimicrobial agents and chemotherapy 2013 topics set
Increased Learning and Brain Long-Term Potentiation in Aged Mice Lacking DNA Polymerase μ. Daniel Lucas, José M Delgado-García, Beatriz Escudero, Carmen Albo, Ana Aza, Rebeca Acín-Pérez, Yaima Torres, Paz Moreno, José Antonio Enríquez, Enrique Samper, Luis Blanco, Alfonso Fairén, Antonio Bernad, Agnès Gruart PloS one 2013 new
Removal of misincorporated ribonucleotides from prokaryotic genomes: an unexpected role for nucleotide excision repair. Alexandra Vaisman, John P McDonald, Donald Huston, Wojciech Kuban, Lili Liu, Bennett Van Houten, Roger Woodgate PLoS genetics 2013 partial results
ATR-Chk1-APC/CCdh1-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress. Masayuki Yamada, Kenji Watanabe, Martin Mistrik, Eva Vesela, Iva Protivankova, Niels Mailand, Myunghee Lee, Hisao Masai, Jiri Lukas, Jiri Bartek Genes & development 2013 topics set
Novel piperidinylamino-diarylpyrimidine derivatives with dual structural conformations as potent HIV-1 non-nucleoside reverse transcriptase inhibitors. Xuwang Chen, Xin Liu, Qing Meng, Ding Wang, Huiqing Liu, Erik De Clercq, Christophe Pannecouque, Jan Balzarini, Xinyong Liu Bioorganic & medicinal chemistry letters 2013 pols set
Sulfolobus chromatin proteins modulate strand displacement by DNA polymerase B1. Fei Sun, Li Huang Nucleic acids research 2013 pols set
DNA polymerase V kinetics support the instructive nature of an oxidized abasic lesion in Escherichia coli. John Ernest V Bajacan, Marc M Greenberg Biochemistry 2013 topics set
New insights in the ϕ29 terminal protein DNA-binding and host nucleoid localization functions. Isabel Holguera, Modesto Redrejo-Rodríguez, Margarita Salas, Daniel Muñoz-Espín Molecular microbiology 2013 new
PrimPol, an Archaic Primase/Polymerase Operating in Human Cells. Sara García-Gómez, Aurelio Reyes, María I Martínez-Jiménez, E Sandra Chocrón, Silvana Mourón, Gloria Terrados, Christopher Powell, Eduardo Salido, Juan Méndez, Ian J Holt, Luis Blanco Molecular cell 2013 new
DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7,8-dihydroguanine bypass. Giovanni Maga, Emmanuele Crespan, Enni Markkanen, Ralph Imhof, Antonia Furrer, Giuseppe Villani, Ulrich Hübscher, Barbara van Loon Proceedings of the National Academy of Sciences of the United States of America 2013 new
Replication, Repair and Translesion Polymerase Bypass of N6-Oxopropenyl-2'-deoxyadenosine. Leena Maddukuri, Sarah C Shuck, Robert Lawton Eoff, Linlin Zhao, Carmelo J Rizzo, F Peter Guengerich, Lawrence J Marnett Biochemistry 2013 complete Brad Langhorst
The mechanism of human tyrosyl-DNA phosphodiesterase 1 in the cleavage of AP site and its synthetic analogs. Natalia A Lebedeva, Nadejda I Rechkunova, Alexander A Ishchenko, Murat Saparbaev, Olga I Lavrik DNA repair 2013 topics set
Expanding the Scope of Human DNA Polymerase λ and β Inhibitors. Tobias Strittmatter, Anette Brockmann, Moritz Pott, Annika Hantusch, Thomas Brunner, Andreas Marx ACS chemical biology 2013 topics set
A cyclobutane thymine-N4-methylcytosine dimer is resistant to hydrolysis but strongly blocks DNA synthesis. Junpei Yamamoto, Tomoko Oyama, Tomohiro Kunishi, Chikahide Masutani, Fumio Hanaoka, Shigenori Iwai Nucleic acids research 2013 topics set
Oxidative stress-induced mutagenesis in single-strand DNA occurs primarily at cytosines and is DNA polymerase zeta-dependent only for adenines and guanines. Natalya P Degtyareva, Lanier Heyburn, Joan F Sterling, Michael A Resnick, Dmitry A Gordenin, Paul W Doetsch Nucleic acids research 2013 new
Molecular dynamics study of HIV-1 RT-DNA-Nevirapine complexes explains NNRTI inhibition, and resistance by connection mutations. R S K Vijayan, Edward Arnold, Kalyan Das Proteins 2013 pols set
The E295K cancer variant of human polymerase beta favors the mismatch conformational pathway during nucleotide selection. Brian E Eckenroth, Jamie B Towle-Weicksel, Joann B Sweasy, Sylvie Doubli Eacute The Journal of biological chemistry 2013 topics set
Structures of an apo and a binary complex of an evolved archeal B family DNA polymerase capable of synthesising highly cy-dye labelled DNA. Samantha A Wynne, Vitor B Pinheiro, Philipp Holliger, Andrew G W Leslie PloS one 2013 new
DNA polymerase ζ as a potential biomarker of chemoradiation resistance and poor prognosis for cervical cancer. Ting-Yan Shi, Li Yang, Gong Yang, Xiao-Yu Tu, Xiaohua Wu, Xi Cheng, Qingyi Wei Medical oncology (Northwood, London, England) 2013 topics set
Measuring and modeling the kinetics of individual DNA-DNA polymerase complexes on a nanopore. Hongyun Wang, Nicholas Hurt, William B Dunbar ACS nano 2013 complete Brad Langhorst
Novel DNA polymerase mutations conferring cytomegalovirus resistance: input of BAC-recombinant phenotyping and 3D model. Sébastien Hantz, Sébastien Cotin, Eva Borst, Anthony Couvreux, Arielle Salmier, Isabelle Garrigue, Pierre Merville, Catherine Mengelle, Michel Attal, Martin Messerle, Sophie Alain Antiviral research 2013 topics set
PCNA trimer instability inhibits translesion synthesis by DNA polymerase η and by DNA polymerase δ. Lynne M Dieckman, M Todd Washington DNA repair 2013 topics set
The Nucleoside Reverse Transcriptase Inhibitors, Nonnucleoside Reverse Transcriptase Inhibitors, and Protease Inhibitors in the Treatment of HIV Infections (AIDS). Erik De Clercq Advances in pharmacology (San Diego, Calif.) 2013 pols set
An iron-sulfur cluster in the polymerase domain of yeast DNA polymerase ε Rinku Jain, Eva S Vanamee, Boris G Dzikovski, Angeliki Buku, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Journal of molecular biology 2013 topics set
Molecular Basis for DNA Double-Strand Break Annealing and Primer Extension by an NHEJ DNA Polymerase. Nigel C Brissett, Maria Jose Martin, Edward J Bartlett, Julie Bianchi, Luis Blanco, Aidan J Doherty Cell reports 2013 topics set
Carcinogenic adducts induce distinct DNA polymerase binding orientations. KB Vrtis, RP Markiewicz, Louis J Romano, David Rueda Nucleic acids research 2013 new
Snapshot of a DNA polymerase while incorporating two consecutive C5-modified nucleotides. Samra Obeid, H Bußkamp, Wolfram Welte, Kay Diederichs, Andreas Marx Journal of the American Chemical Society 2013 topics set
The Architecture of Yeast DNA Polymerase ζ Yacob Gómez-Llorente, Radhika Malik, Rinku Jain, Jayati Roy Choudhury, Robert E Johnson, Louise Prakash, Satya Prakash, Iban Ubarretxena-Belandia, Aneel K Aggarwal Cell reports 2013 topics set
Ultra-Sensitive Sequencing Reveals an Age-Related Increase in Somatic Mitochondrial Mutations That Are Inconsistent with Oxidative Damage. Scott R Kennedy, Jesse J Salk, Michael W Schmitt, Lawrence A Loeb PLoS genetics 2013 topics set
Effects of 4' - and 2-Substitutions on the Bioactivity of 4' -Ethynyl-2-Fluoro-2' -Deoxyadenosine. Karen A Kirby, Eleftherios Michailidis, Tracy L Fetterly, MA Steinbach, Kamalendra Singh, Bruno Marchand, Maxwell D Leslie, Ariel N Hagedorn, Eiichi N Kodama, Victor E Marquez, Stephen H Hughes, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos Antimicrobial agents and chemotherapy 2013 topics set
Strategic Combination of DNA-Damaging Agent and PARP Inhibitor Results in Enhanced Cytotoxicity. Julie K Horton, Samuel H Wilson Frontiers in oncology 2013 new
Dpb2 integrates the leading-strand DNA polymerase into the eukaryotic replisome. Sugopa Sengupta, Frederick van Deursen, Giacomo De Piccoli, Karim Labib Current biology : CB 2013 topics set
Structure-function analysis of ribonucleotide bypass by B family DNA replicases. Anders R Clausen, Michael S Murray, Andrew R Passer, Lars C Pedersen, Thomas A Kunkel Proceedings of the National Academy of Sciences of the United States of America 2013 topics set
Inhibition of HIV-1 Reverse Transcriptase-Catalyzed Synthesis by Intercalated DNA Benzo[a]Pyrene 7,8-Dihydrodiol-9,10-Epoxide Adducts. Parvathi Chary, William A Beard, Samuel H Wilson, R Stephen Lloyd PloS one 2013 topics set
Structure and Function of an RNA-Reading Thermostable DNA Polymerase. Nina Blatter, Konrad Bergen, O Nolte, Wolfgang Welte, Kay Diederichs, J Mayer, M Wieland, Andreas Marx Angewandte Chemie (International ed. in English) 2013 topics set
Effect of Smilax china L.-containing serum on the expression of POLD1 mRNA in human hepatocarcinoma SMMC-7721 cells. Bo Cao, Zihan Zhang, Yuqin Zhang, Jinming Li, Gang Liang, Jianghong Ling Experimental and therapeutic medicine 2013 pols set
Clicking 3'-azidothymidine into novel potent inhibitors of human immunodeficiency virus. Venkata Ramana Sirivolu, Sanjeev Kumar V Verneka, Tatiana Ilina, Nataliya S Myshakina, Michael A. Parniak, Zhengqiang Wang Journal of medicinal chemistry 2013 topics set
DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures. Matthew R Northam, Elizabeth A Moore, Tony M Mertz, Sara K Binz, Carrie M W Stith, Elena I Stepchenkova, Kathern L Wendt, Peter M J Burgers, Polina V Shcherbakova Nucleic acids research 2013 topics set
DNA polymerase δ stalls on telomeric lagging strand templates independently from G-quadruplex formation. JD Lormand, N Buncher, CT Murphy, P Kaur, Marietta Y W T Lee, P Burgers, Hongyun Wang, Thomas A Kunkel, Patricia L Opresko Nucleic acids research 2013 topics set
Kinetic Mechanism of DNA Polymerization Catalyzed by Human DNA Polymerase ε Walter J Zahurancik, Seth J Klein, Zucai Suo Biochemistry 2013 topics set
Dual Role of φ29 DNA Polymerase Lys529 in Stabilisation of the DNA Priming-Terminus and the Terminal Protein-Priming Residue at the Polymerisation Site. Alicia Del Prado, José María Lázaro, Laurentino Villar, Margarita Salas, Miguel de Vega PloS one 2013 topics set
Dynamics of enzymatic interactions during short flap human Okazaki fragment processing by two forms of human DNA polymerase δ Szu Hua Sharon Lin, Xiaoxiao Wang, Sufang Zhang, Zhenzhong Zhang, Ernest Y C Lee, Marietta Y W T Lee DNA repair 2013 pols set
Design, Synthesis, and Biological Evaluation of Novel 3,5-Disubstituted-1,2,6-Thiadiazine-1,1-Dione Derivatives as HIV-1 NNRTIs. Ye Tian, Diwakar Rai, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Huiqing Liu, Xinyong Liu Chemical biology & drug design 2013 topics set
A synthetic substrate of DNA polymerase deviating from the bases, sugar, and leaving group of canonical deoxynucleoside triphosphates. Mi-Yeon Jang, Xiao-Ping Song, Mathy Froeyen, Philippe Marlière, Eveline Lescrinier, Jef Rozenski, Piet Herdewijn Chemistry & biology 2013 new
Biochemical, cellular and molecular identification of DNA polymerase α in yeast mitochondria Jean-Paul Lasserre, Jacqueline Plissonneau, Christophe Velours, Marc Bonneu, Simon Litvak, Patricia Laquel, M. Castroviejo Biochem J 2013 new
Discrete interactions between bacteriophage T7 primase-helicase and DNA polymerase drive the formation of a priming complex containing two copies of DNA polymerase. Jamie R Wallen, Jerzy Majka, Tom Ellenberger Biochemistry 2013 new
Development of a genome-wide random mutagenesis system using proofreading-deficient DNA polymerase δ in the methylotrophic yeast Hansenula polymorpha. Oh Cheol Kim, Sang-Yoon Kim, Dong Hyeon Hwang, Doo-Byoung Oh, Hyun Ah Kang, Ohsuk Kwon Journal of microbiology and biotechnology 2013 topics set
Biochemical, cellular and molecular identification of DNA polymerase α in yeast mitochondria. Jean-Paul Lasserre, Jacqueline Plissonneau, Christophe Velours, Marc Bonneu, Simon Litvak, Patricia Laquel, Michel Castroviejo Biochimie 2013 new
Dynamics of Hepatitis B Virus Resistance Substitutions Correlates with Virological Response in Lamivudine-Refractory Patients with Entecavir Rescue Monotherapy. Yan Zhang, Song He, Qing-Ling Li, Jin-Jun Guo Virus research 2013 new
A Multi-targeted Drug Candidate with Dual Anti-HIV and Anti-HSV Activity. Jan Balzarini, Graciela Andrei, Emanuela Balestra, Dana Huskens, Christophe Vanpouille, Andrea Introini, Sonia Zicari, Sandra Liekens, Robert Snoeck, Antonín Holý, CF Perno, Leonid Margolis, Dominique Schols PLoS pathogens 2013 topics set
Dynamics of DNA polymerase I (Klenow fragment) under external force. Ping Xie Journal of molecular modeling 2013 topics set
Dynamics of site switching in DNA polymerase. Rajan Lamichhane, Svitlana Y Berezhna, JP Gill, Edwin J C Van der Schans, David P Millar Journal of the American Chemical Society 2013 new
PDIP38 is translocated to the spliceosomes/nuclear speckles in response to UV-induced DNA damage and is required for UV-induced alternative splicing of MDM2. Agnes Wong, Sufang Zhang, Dana Mordue, Joseph M Wu, Zhongtao Zhang, Zbigniew Darzynkiewicz, Ernest Y C Lee, Marietta Y W T Lee Cell cycle (Georgetown, Tex.) 2013 new
Incorporation of Nucleoside Probes Opposite O(6) -Methylguanine by Sulfolobus solfataricus DNA Polymerase Dpo4: Importance of Hydrogen Bonding. Alessia Stornetta, Todor Angelov, F Peter Guengerich, Shana J Sturla Chembiochem : a European journal of chemical biology 2013 pols set
Homocysteine-related hTERT DNA demethylation contributes to shortened leukocyte telomere length in atherosclerosis. Donghong Zhang, Xuemei Wen, Wei Wu, Ermu Xu, Yujuan Zhang, Wei Cui Atherosclerosis 2013 pols set
Involvement of DNA polymerase β overexpression in the malignant transformation induced by benzo[a]pyrene. Wei Zhao, Mei Wu, Yanhao Lai, Wenwen Deng, Yuan Liu, Zhenzhong Zhang Toxicology 2013 topics set
Tissue-engineered allograft intervertebral disc transplantation for the treatment of degenerative disc disease: experimental study in a beagle model. Hongkui Xin, Chao Zhang, Deli Wang, Zhiyuan Shi, Tao Gu, Chaofeng Wang, Jianhong Wu, Yongqing Zhang, Qing He, Dike Ruan Tissue engineering. Part A 2013 new
Recruitment of DNA polymerase eta by FANCD2 in the early response to DNA damage. Dechen Fu, Fred Duafalia Dudimah, Jun Zhang, Anna Pickering, Jayabal Paneerselvam, Manikandan Palrasu, Hong Wang, Peiwen Fei Cell cycle (Georgetown, Tex.) 2013 topics set
First-passage problems in DNA replication: effects of template tension on stepping and exonuclease activities of a DNA polymerase motor. Ajeet K Sharma, Debashish Chowdhury Journal of physics. Condensed matter : an Institute of Physics journal 2013 new
Clustered DNA Lesions Containing 5-Formyluracil and AP Site: Repair via the BER System. Ekaterina A Belousova, Inna A Vasil'eva, Nina A Moor, Timofey S Zatsepin, Tatiana S Oretskaya, Olga I Lavrik PloS one 2013 topics set
Overexpressed DNA Polymerase Iota Regulated by JNK/c-Jun Contributes to Hypermutagenesis in Bladder Cancer. Fenghua Yuan, Zhigang Xu, Mingzhen Yang, Quanfang Wei, Yongqing Zhang, Jin Yu, Yi Zhi, Yang Liu, Zhiwen Chen, Jin Yang PloS one 2013 topics set
Analysis of Ig gene hypermutation in Ung(-/-)Polh(-/-) mice suggests that UNG and A:T mutagenesis pathway target different U:G lesions. Shuyin Li, Yaofeng Zhao, Ji-Yang Wang Molecular immunology 2013 new
A Substitution in the Fingers Domain of DNA Polymerase Delta Reduces Fidelity by Altering Nucleotide Discrimination in the Catalytic Site. Marc J Prindle, Michael W Schmitt, Fabio Parmeggiani, Lawrence A Loeb The Journal of biological chemistry 2013 new
DNA polymerization-independent functions of DNA polymerase epsilon in assembly and progression of the replisome in fission yeast. Tetsuya Handa, Mai Kanke, Tatsuro S Takahashi, Takuro Nakagawa, Hisao Masukata Molecular biology of the cell 2012 new
Thermodynamic and mechanistic insights into translesion DNA synthesis catalyzed by Y-family DNA polymerase across a bulky double-base lesion of an antitumor platinum drug. V Brabec, J Malina, N Margiotta, G Natile, J Kasparkova Chemistry (Weinheim an der Bergstrasse, Germany) 2012 topics set
Balancing Antiviral Potency and Host Toxicity: Identifying a Nucleotide Inhibitor with an Optimal Kinetic Phenotype for HIV-1 Reverse Transcriptase. Christal D Sohl, Rajesh Kasiviswanathan, Jiae Kim, Ugo Pradere, Raymond F Schinazi, William C Copeland, Hiroyuki Mitsuya, Masanori Baba, Karen S Anderson Molecular pharmacology 2012 topics set
Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy. Ajay Ummat, Olga Rechkoblit, Rinku Jain, Jayati Roy Choudhury, Robert E Johnson, Timothy D Silverstein, Angeliki Buku, Samer Lone, Louise Prakash, Satya Prakash, Aneel K Aggarwal Nature structural & molecular biology 2012 topics set
Human DNA polymerase λ catalyzes lesion bypass across benzo[a]pyrene-derived DNA adduct during base excision repair. Lidia V Skosareva, Natalia A Lebedeva, Nadejda I Rechkunova, Alexander Kolbanovskiy, Nicholas E Geacintov, Olga I Lavrik DNA repair 2012 topics set
Evidence for Abasic Site Sugar Phosphate-Mediated Cytotoxicity in Alkylating Agent Treated Saccharomyces cerevisiae. Michelle L Heacock, Vladimir P Poltoratsky, Rajendra Prasad, Samuel H Wilson PloS one 2012 new
Inhibitory effects of glycyrrhetinic Acid on DNA polymerase and inflammatory activities. Tsukasa Ishida, Yoshiyuki Mizushina, Saori Yagi, Yasuhiro Irino, Shin Nishiumi, Ikuya Miki, Yasuyuki Kondo, Shigeto Mizuno, Hiromi Yoshida, Takeshi Azuma, Masaru Yoshida Evidence-based complementary and alternative medicine : eCAM 2012 new
Mechanisms Employed by Escherichia coli to Prevent Ribonucleotide Incorporation into Genomic DNA by Pol V. John P McDonald, Alexandra Vaisman, Wojciech Kuban, Myron F Goodman, Roger Woodgate PLoS genetics 2012 new
DNA expansions generated by human Polμ on iterative sequences. Ana Aza, Maria Jose Martin, Raquel Juarez, Luis Blanco, Gloria Terrados Nucleic acids research 2012 new
Suppression of NPC tumor growth by hTERTC27 polypeptide delivered through AAV plus Adv vector cocktail. Xiong Liu, Xiang-Ping Li, Ying Peng, Samuel S M Ng, Hong Yao, Zi-Feng Wang, Xiao-Mei Wang, Hsiang-Fu Kung, Marie Chia-Mi Lin Chinese journal of cancer 2012 new
Structural basis of the allosteric inhibitor interaction on the HIV-1 reverse transcriptase RNase H domain. Martin T Christen, Lakshmi Menon, Nataliya S Myshakina, Jinwoo Ahn, Michael A. Parniak, Rieko Ishima Chemical biology & drug design 2012 pols set
Establishment and evaluation of a stable steroidogenic caprine luteal cell line. Wei Li, Xingang Xu, Yong Huang, Zhongjie Li, Gaoshui Yu, Zhisheng Wang, Li Ding, Dewen Tong Theriogenology 2012 new
The Human POLB Gene is Mutated in a High Percentage of Colorectal Tumors. Katherine A Donigan, Ka-Wai Sun, Antonia A Nemec, Drew L Murphy, Xiangyu Cong, Veronika Northrup, Daniel Zelterman, Joann B Sweasy The Journal of biological chemistry 2012 topics set
Inhibitors of HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity. Tatiana Ilina, Krystal Labarge, Stefan G Sarafianos, Rieko Ishima, Michael A. Parniak Biology 2012 complete Tatiana Ilina*
Dysregulation of DNA polymerase κ recruitment to replication forks results in genomic instability. Mathew Jk Jones, Luca Colnaghi, Tony T Huang The EMBO journal 2012 topics set
Host cell nucleolin is required to maintain the architecture of human cytomegalovirus replication compartments. Blair L Strang, Steeve Boulant, Tomas Kirchhausen, Donald M Coen mBio 2012 topics set
Ribonucleotide incorporation, proofreading and bypass by human DNA polymerase δ Anders R Clausen, Sufang Zhang, Peter M J Burgers, Marietta Y W T Lee, Thomas A Kunkel DNA repair 2012 new
(Z)-5-(4-methoxybenzylidene)thiazolidine-2,4-dione protects rats from carbon tetrachloride-induced liver injury and fibrogenesis. Zhi-Zhi Chen, Zheng-Lin Wang, Chong-Yang Deng, Hao Zheng, Xian-Huo Wang, Liang Ma, Xia Ye, Ying-Hua Ma, Cai-Feng Xie, Li-Juan Chen, Yu-Quan Wei World journal of gastroenterology : WJG 2012 new
Monogalactosyl diacylglycerol, a replicative DNA polymerase inhibitor, from spinach enhances the anti-cell proliferation effect of gemcitabine in human pancreatic cancer cells. Hiroaki Akasaka, Ryohei Sasaki, Kenji Yoshida, Izumi Takayama, Tsuyoshi Yamaguchi, Hiromi Yoshida, Yoshiyuki Mizushina Biochimica et biophysica acta 2012 new
Mechanism of Replicative DNA Polymerase Delta Pausing and a Potential Role for DNA Polymerase Kappa in Common Fragile Site Replication. Erin Walsh, Xiaoxiao Wang, Marietta Y W T Lee, Kristin A Eckert Journal of molecular biology 2012 new
MsDpo4-a DinB Homolog from Mycobacterium smegmatis-Is an Error-Prone DNA Polymerase That Can Promote G:T and T:G Mismatches. Amit Sharma, Deepak T Nair Journal of nucleic acids 2012 topics set
The C-terminal domain of human Rev1 contains independent binding sites for DNA polymerase η and Rev7 subunit of polymerase ζ. Yulia Pustovalova, Irina Bezsonova, Dmitry M Korzhnev FEBS letters 2012 pols set
DNA polymerase beta (pol β) inhibitors: a comprehensive overview. KH Barakat, MM Gajewski, JA Tuszynski Drug discovery today 2012 topics set
Gene 5.5 protein of bacteriophage T7 in complex with Escherichia coli nucleoid protein H-NS and transfer RNA masks transfer RNA priming in T7 DNA replication. B Zhu, Seung-Joo Lee, Min Tan, En-Duo Wang, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 2012 new
A comparison of the ability of rilpivirine (TMC278) and selected analogues to inhibit clinically relevant HIV-1 reverse transcriptase mutants. Barry C Johnson, Gary T Pauly, Ganesha Rai, Disha Patel, Joseph David Bauman, Heather L Baker, Kalyan Das, Joel P Schneider, David J Maloney, Edward Arnold, Craig J Thomas, Stephen H Hughes Retrovirology 2012 pols set
Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase δ for degradation in response to DNA damage. Sufang Zhang, Yajing Zhou, Ali Sarkeshik, John Yates, Timothy M Thomson, Zhongtao Zhang, Ernest Y C Lee, Marietta Y W T Lee The Journal of biological chemistry 2012 topics set
Defect of Dpb2p, a noncatalytic subunit of DNA polymerase ɛ, promotes error prone replication of undamaged chromosomal DNA in Saccharomyces cerevisiae. Joanna Kraszewska, Marta Garbacz, Piotr Jonczyk, Iwona J Fijalkowska, Malgorzata Jaszczur Mutation research 2012 topics set
Analysis of mice deficient in both REV1 catalytic activity and POLH reveals an unexpected role for POLH in the generation of C to G and G to C transversions during Ig gene hypermutation. Chie Kano, Fumio Hanaoka, Ji-Yang Wang International immunology 2012 topics set
Segregation of replicative DNA polymerases during S phase: DNA polymerase ε, but not DNA polymerases α/δ, are associated with lamins throughout S phase in human cells. Markku Vaara, Harri Itkonen, Tomi Hillukkala, Zhe Liu, Heinz Peter Nasheuer, Daniel Schaarschmidt, Helmut Pospiech, Juhani E Syväoja The Journal of biological chemistry 2012 topics set
KlenTaq DNA polymerase adopts unique recognition states when encountering matched, mismatched, and abasic template sites: an NMR study. Bastian Holzberger, M Gabriele Pszolla, Andreas Marx, Heiko M Möller Chembiochem : a European journal of chemical biology 2012 new
Regulation of oxidative DNA damage repair: The adenine:8-oxo-guanine problem. Enni Markkanen, Ulrich Hübscher, Barbara van Loon Cell cycle (Georgetown, Tex.) 2012 new
DNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesion. Bret D Freudenthal, William A Beard, Samuel H Wilson Nucleic acids research 2012 new
Defects in mitochondrial DNA replication and human disease. William C Copeland Critical reviews in biochemistry and molecular biology 2012 new
Synthesis and biological evaluation of piperidine-substituted triazine derivatives as HIV-1 non-nucleoside reverse transcriptase inhibitors. Xuwang Chen, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu European journal of medicinal chemistry 2012 pols set
Influence of usnic acid and its derivatives on the activity of mammalian poly(ADP-ribose)polymerase 1 and DNA polymerase β. Alexandra Zakharenko, Dmitry Sokolov, Olga Luzina, Maria V Sukhanova, Svetlana N Khodyreva, Olga Zakharova, Nariman Salakhutdinov, Olga I Lavrik Medicinal chemistry (Shāriqah (United Arab Emirates)) 2012 new
Differential Furanose Selection in the Active Sites of Archaeal DNA Polymerases Probed by Fixed-Conformation Nucleotide Analogues. Amit Ketkar, Maroof Khan Zafar, Surajit Banerjee, Victor E Marquez, Martin Egli, Robert Lawton Eoff Biochemistry 2012 topics set
Structural basis of recruitment of DNA polymerase ζ by interaction between REV1 and REV7 proteins. Sotaro Kikuchi, Kodai Hara, Toshiyuki Shimizu, Mamoru Sato, Hiroshi Hashimoto The Journal of biological chemistry 2012 topics set
Characterization of catalytic carboxylate triad in non-replicative DNA polymerase III (pol E) of Geobacillus kaustophilus HTA. Cemal Sandalli, Kamalendra Singh, Mukund J Modak Cellular and molecular biology (Noisy-le-Grand, France) 2012 topics set
Structures of KlenTaq DNA polymerase caught while incorporating C5-modified pyrimidine and C7-modified 7-deazapurine nucleoside triphosphates. Konrad Bergen, Anna-Lena Steck, Stefan Strütt, Anna Baccaro, Wolfram Welte, Kay Diederichs, Andreas Marx Journal of the American Chemical Society 2012 topics set
Solution structure and conformational dynamics of deoxyxylonucleic acids (dXNA): an orthogonal nucleic acid candidate. Mohitosh Maiti, Vanessa Siegmund, Mikhail Abramov, Eveline Lescrinier, Helmut Rosemeyer, Mathy Froeyen, Amutha Ramaswamy, Arnout Ceulemans, Andreas Marx, Piet Herdewijn Chemistry (Weinheim an der Bergstrasse, Germany) 2012 new
Overexpression of the mTERT gene by adenoviral vectors promotes the proliferation of neuronal stem cells in vitro and stimulates neurogenesis in the hippocampus of mice. Mengying Liu, Yao Hu, Lijuan Zhu, Chen Chen, Yongqing Zhang, Weixiang Sun, Qigang Zhou Journal of biomedical research 2012 pols set
A comprehensive strategy to discover inhibitors of the translesion synthesis DNA polymerase κ. Kinrin Yamanaka, Dorjbal Dorjsuren, Robert Lawton Eoff, Martin Egli, David J Maloney, Ajit Jadhav, Anton Simeonov, R Stephen Lloyd PloS one 2012 topics set
2-(Alkyl/Aryl)Amino-6-Benzylpyrimidin-4(3H)-ones as Inhibitors of Wild-Type and Mutant HIV-1: Enantioselectivity Studies. Dante Rotili, Alberta Samuele, Domenico Tarantino, Rino Ragno, Ira Musmuca, Flavio Ballante, Giorgia Botta, Ludovica Morera, Marco Pierini, Roberto Cirilli, Maxim B Nawrozkij, Emmanuel Gonzalez, B Clotet, Marino Artico, José A Esté, Giovanni Maga, Antonello Mai Journal of medicinal chemistry 2012 pols set
The role of the PHP domain associated with DNA polymerase X from Thermus thermophilus HB8 in base excision repair. Shuhei Nakane, Noriko Nakagawa, Seiki Kuramitsu, Ryoji Masui DNA repair 2012 topics set
A DNA lesion alters the global conformational dynamics of a Y-Family DNA polymerase during catalysis. Brian A Maxwell, Cuiling Xu, Zucai Suo The Journal of biological chemistry 2012 new
Y265C DNA polymerase beta knockin mice survive past birth and accumulate base excision repair intermediate substrates. Alireza G Senejani, Shibani Dalal, Yanfeng Liu, Timothy P Nottoli, James M McGrath, Connor S Clairmont, Joann B Sweasy Proceedings of the National Academy of Sciences of the United States of America 2012 new
Antifungal properties of Japanese cedar essential oil from waste wood chips made from used sake barrels. Yoshifumi Takao, Isoko Kuriyama, Tasuku Yamada, Haruhiko Mizoguchi, Hiromi Yoshida, Yoshiyuki Mizushina Molecular medicine reports 2012 new
Chiral resolution, absolute configuration assignment and biological activity of racemic diarylpyrimidine CH(OH)-DAPY as potent nonnucleoside HIV-1 reverse transcriptase inhibitors. Shuang-Xi Gu, Zhi-Ming Li, Xiao-Dong Ma, Shi-Qiong Yang, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque European journal of medicinal chemistry 2012 pols set
Potential of carbohydrate-binding agents as therapeutics against enveloped viruses. K O François, Jan Balzarini Medicinal research reviews 2012 pols set
RNase H2-Initiated Ribonucleotide Excision Repair. Justin L Sparks, Hyongi Chon, Susana M Cerritelli, Thomas A Kunkel, Erik Johansson, Robert J Crouch, Peter M J Burgers Molecular cell 2012 new
Structure-based bioisosterism design, synthesis and biological evaluation of novel 1,2,4-triazin-6-ylthioacetamides as potent HIV-1 NNRTIs. Peng Zhan, Xincang Li, Zhongjie Li, Xuwang Chen, Ye Tian, Wenmin Chen, Xinyong Liu, Christophe Pannecouque, Erik De Clercq Bioorganic & medicinal chemistry letters 2012 pols set
Characterization and PCR application of a new high-fidelity DNA polymerase from Thermococcus waiotapuensis. Sung Suk Cho, Kee Pum Kim, Kang Keun Lee, Man-Hui Youn, Suk-Tae Kwon Enzyme and microbial technology 2012 topics set
Subtractive genomics approach to identify putative drug targets and identification of drug-like molecules for beta subunit of DNA polymerase III in Streptococcus species. John J Georrge, V V Umrania Applied biochemistry and biotechnology 2012 topics set
Exploiting the anti-HIV-1 activity of acyclovir: suppression of primary and drug-resistant HIV isolates and potentiation of the activity by ribavirin. Christophe Vanpouille, Andrea Lisco, Andrea Introini, Jean-Charles Grivel, Arshi Munawwar, Melanie Merbah, Raymond F Schinazi, Marco Derudas, Christopher McGuigan, Jan Balzarini, Leonid Margolis Antimicrobial agents and chemotherapy 2012 pols set
Dynamic localization of Trypanosoma brucei mitochondrial DNA polymerase ID. Jeniffer Concepción-Acevedo, Juemin Luo, Michele M Klingbeil Eukaryotic cell 2012 pols set
Proofreading of ribonucleotides inserted into DNA by yeast DNA polymerase ɛ Jessica S Williams, Anders R Clausen, Stephanie A Nick McElhinny, Brian E Watts, Erik Johansson, Thomas A Kunkel DNA repair 2012 topics set
Recent advances in the research of 2,3-diaryl-1,3-thiazolidin-4-one derivatives as potent HIV-1 non-nucleoside reverse transcriptase inhibitors. Ye Tian, Peng Zhan, Diwakar Rai, Jiyan Zhang, Erik De Clercq, Xinyong Liu Current medicinal chemistry 2012 pols set
Computational prediction of residues involved in fidelity checking for DNA synthesis in DNA polymerase I. Sarah E Graham, FatimaSultana Syeda, G Andrés Cisneros Biochemistry 2012 complete G Andrés Cisneros*
Characterization of the DNA primase complex isolated from the archaeon, Thermococcus kodakaraensis. Wiebke Chemnitz Galal, Miao Pan, Zvi Kelman, Jerard Hurwitz The Journal of biological chemistry 2012 topics set
Perspective: pre-chemistry conformational changes in DNA polymerase mechanisms. Tamar Schlick, Karunesh Arora, William A Beard, Samuel H Wilson Theoretical chemistry accounts 2012 new
In vitro-selected drug-resistant varicella-zoster virus mutants in the thymidine kinase and DNA polymerase genes yield novel phenotype-genotype associations and highlight differences between antiherpesvirus drugs. Gracíela Andrei, Dimitri Topalis, Pierre Fiten, Christopher McGuigan, Jan Balzarini, Ghislain Opdenakker, Robert Snoeck Journal of virology 2012 new
Complete sequence analysis of 18S rDNA based on genomic DNA extraction from individual Demodex mites (Acari: Demodicidae). Ya-E Zhao, Ji-Ru Xu, Li Hu, Li-Ping Wu, Zheng-Hang Wang Experimental parasitology 2012 new
The human gastric cancer-associated DNA polymerase β variant D160N is a mutator that induces cellular transformation. Katherine A Donigan, Suzanne E Hile, Kristin A Eckert, Joann B Sweasy DNA repair 2012 topics set
I-PfoP3I: a novel nicking HNH homing endonuclease encoded in the group I intron of the DNA polymerase gene in Phormidium foveolarum phage Pf-WMP3. Shuanglei Kong, Xinyao Liu, Liwen Fu, Xiangchun Yu, Chengcai An PloS one 2012 new
Antiviral therapies: Focus on hepatitis B reverse transcriptase. Eleftherios Michailidis, Karen A Kirby, Atsuko Hachiya, Wangdon Yoo, Sun Pyo Hong, Soo-Ok Kim, William R Folk, Stefan G Sarafianos The international journal of biochemistry & cell biology 2012 topics set
DNA polymerase eta participates in the mutagenic bypass of adducts induced by benzo[a]pyrene diol epoxide in mammalian cells. Alden C Klarer, L Jay Stallons, Tom J Burke, Robert L Skaggs, W Glenn McGregor PloS one 2012 topics set
DNA stabilization at the Bacillus subtilis PolX core--a binding model to coordinate polymerase, AP-endonuclease and 3'-5' exonuclease activities. Benito Baños, Laurentino Villar, Margarita Salas, Miguel de Vega Nucleic acids research 2012 topics set
The interplay of DNA polymerase λ in diverse DNA damage repair pathways in higher plant genome in response to environmental and genotoxic stress factors. Sujit Roy, Swarup Roy Choudhury, Kalipada Das Plant signaling & behavior 2012 new
GCN5 protects vertebrate cells against UV-irradiation via controlling gene expression of DNA polymerase η. Hidehiko Kikuchi, Futoshi Kuribayashi, Shinobu Imajoh-Ohmi, Hideki Nishitoh, Yasunari Takami, Tatsuo Nakayama The Journal of biological chemistry 2012 new
How conformational dynamics of DNA polymerase select correct substrates: experiments and simulations. Serdal Kirmizialtin, Virginia Nguyen, Kenneth A Johnson, Ron Elber Structure (London, England : 1993) 2012 pols set
DNA base excision repair: a mechanism of trinucleotide repeat expansion. Yuan Liu, Samuel H Wilson Trends in biochemical sciences 2012 complete Yuan Liu*
A Support Vector Machine Based Method to Predict Success for Polymerase Chain Reactions. Xiaoqing Yu, Xiaoqi Zheng, Liangyu Meng, Chun Li, Jun Wang Combinatorial chemistry & high throughput screening 2012 pols set
Improved gap repair cloning in yeast: treatment of the gapped vector with Taq DNA polymerase avoids vector self-ligation. Daniela Bessa, Filipa Pereira, Roxana Moreira, Björn Johansson, Odília Queirós Yeast (Chichester, England) 2012 pols set
Association between newly identified variant form of DNA polymerase beta (Δ 208-304) and ovarian cancer. Kalyani Khanra, Kakali Panda, Chandan Bhattacharya, Ak Mitra, Ranu Sarkar, Sanjeev Banerjee, Nandan Bhattacharyya Cancer biomarkers : section A of Disease markers 2012 topics set
Structural basis of human DNA polymerase η-mediated chemoresistance to cisplatin. Yaofeng Zhao, Christian Biertümpfel, Mark T Gregory, Yue-Jin Hua, Fumio Hanaoka, Wei Wen Yang Proceedings of the National Academy of Sciences of the United States of America 2012 topics set
Ribonucleotides and manganese ions improve non-homologous end joining by human Polμ Maria Jose Martin, Maria V Garcia-Ortiz, Veronica Esteban, Luis Blanco Nucleic acids research 2012 pols set
Enhancement of human DNA polymerase η activity and fidelity is dependent upon a bipartite interaction with the Werner syndrome protein. Leena Maddukuri, Amit Ketkar, Sarah Eddy, Maroof Khan Zafar, Wezley C Griffin, Robert Lawton Eoff The Journal of biological chemistry 2012 new
Kinetic Basis for Differing Response to an Oxidative Lesion by a Replicative and a Lesion Bypass DNA Polymerase from Solfolobus Solfataricus. Brian A Maxwell, Zucai Suo Biochemistry 2012 new
Substrate-Dependent Millisecond Domain Motions in DNA Polymerase β Rebecca B Berlow, Monalisa Swain, Shibani Dalal, Joann B Sweasy, J Patrick Loria Journal of molecular biology 2012 new
Measuring cation dependent DNA polymerase fidelity landscapes by deep sequencing. Bradley Michael Zamft, Adam H Marblestone, Konrad Kording, Daniel Schmidt, Daniel Martin-Alarcon, Keith Tyo, Edward S Boyden, George Church PloS one 2012 new
Interactions of non-polar and "Click-able" nucleotides in the confines of a DNA polymerase active site. Samra Obeid, Holger Busskamp, Wolfgang Welte, Kay Diederichs, Andreas Marx Chemical communications (Cambridge, England) 2012 new
The human lagging strand DNA polymerase δ holoenzyme is distributive. Zhenxin Hu, Senthil K Perumal, Hongjun Yue, Stephen J Benkovic The Journal of biological chemistry 2012 topics set
Structural Basis for Differential Insertion Kinetics of dNMPs Opposite a Difluorotoluene Nucleotide Residue. Shuangluo Xia, Soo Hyun Eom, William H Konigsberg, Jianhong Wang Biochemistry 2012 pols set
Selection and characterization of Autographa californica multiple nucleopolyhedrovirus DNA polymerase mutations. Guozhong Feng, David K Thumbi, Jondavid de Jong, Jeffrey J Hodgson, Basil M Arif, Daniel Doucet, Peter J Krell Journal of virology 2012 new
Kinetics and fidelity of polymerization by DNA polymerase III from Sulfolobus solfataricus. Robert J Bauer, Michael T Begley, Michael A Trakselis Biochemistry 2012 new
The Werner syndrome exonuclease facilitates DNA degradation and high fidelity DNA polymerization by human DNA polymerase δ Ashwini S Kamath-Loeb, Jiang-Cheng Shen, Michael W Schmitt, Lawrence A Loeb The Journal of biological chemistry 2012 topics set
DNA Mismatch Synthesis Complexes Provide Insights into Base Selectivity of a B Family DNA Polymerase. Shuangluo Xia, Jianhong Wang, William H Konigsberg Journal of the American Chemical Society 2012 new
Inhibition of Taq DNA polymerase by iridoid aglycone derivates. Carlos Rodolfo Pungitore, Celina García, V Sotero Martín, Carlos E Tonn Cellular and molecular biology (Noisy-le-Grand, France) 2012 pols set
Mitochondrial DNA copy number is regulated in a tissue specific manner by DNA methylation of the nuclear-encoded DNA polymerase gamma A. Richard D W Kelly, Arsalan Mahmud, Matthew McKenzie, Ian A Trounce, Justin C St John Nucleic acids research 2012 new
NMR structure and dynamics of the C-terminal domain from human Rev1 and its complex with Rev1 interacting region of DNA polymerase η. Alexandra Pozhidaeva, Yulia Pustovalova, Sanjay D'Souza, Irina Bezsonova, Graham C Walker, Dmitry M Korzhnev Biochemistry 2012 new
The HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors (Part V ☆ ): Capravirine and Its Analogues. Xincang Li, Peng Zhan, Erik De Clercq, Xinyong Liu Current medicinal chemistry 2012 pols set
Kinetic Analysis of the Bypass of a Bulky DNA Lesion Catalyzed by Human Y-family DNA Polymerases. Shanen M Sherrer, Laura E Sanman, Cynthia X Xia, Eric R Bolin, Chanchal K Malik, Georgia Efthimiopoulos, Ashis K Basu, Zucai Suo Chemical research in toxicology 2012 topics set
Watching DNA polymerase η make a phosphodiester bond. Teruya Nakamura, Yaofeng Zhao, Yuriko Yamagata, Yue-Jin Hua, Wei Wen Yang Nature 2012 new
Exonuclease 1 preferentially repairs mismatches generated by DNA polymerase α Sascha E Liberti, Andres A Larrea, Thomas A Kunkel DNA repair 2012 new
J. Biol. Chem. 2012 topics set
Development of a polymerase chain reaction for the detection of abalone herpesvirus infection based on the DNA polymerase gene. M H Chen, S T Kuo, T Renault, C S Friedman, P H Chang Journal of virological methods 2012 new
Disclosing the in vivo organization of a viral histone-like protein in Bacillus subtilis mediated by its capacity to recognize the viral genome. Isabel Holguera, David Ballesteros-Plaza, Daniel Muñoz-Espín, Margarita Salas Proceedings of the National Academy of Sciences of the United States of America 2012 new
Homologous recombination mediates S-phase-dependent radioresistance in cells deficient in DNA polymerase eta. Nils H Nicolay, Rebecca Carter, Stephanie B Hatch, Niklas Schultz, Remko Prevo, W Gillies McKenna, Thomas Helleday, Ricky A Sharma Carcinogenesis 2012 topics set
Maraviroc and other HIV-1 entry inhibitors exhibit a class-specific redistribution effect that results in increased extracellular viral load. Victor G Kramer, Susan M Schader, Maureen Oliveira, Susan P Colby-Germinario, Daniel A Donahue, Diane N Singhroy, Randy Tressler, Richard D Sloan, Mark A. Wainberg Antimicrobial agents and chemotherapy 2012 pols set
Mechanism of taq DNA polymerase inhibition by fullerene derivatives: insight from computer simulations. Praveen Nedumpully Govindan, Luca Monticelli, Emppu Salonen The journal of physical chemistry. B 2012 pols set
REV1 and DNA polymerase zeta in DNA interstrand crosslink repair. S Sharma, CE Canman Environmental and molecular mutagenesis 2012 new
[Purification of Taq DNA polymerase expressed in Escherichia coli]. Tian-Lei Liu, Shou-Bin Xue, Fang Wang, Lin-Ying Zhu, Wei-Wei Liang, Sheng-Xuan Qu, Wen-Bo Cai Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji 2012 pols set
The C-terminus of Dpb2 is required for interaction with Pol2 and for cell viability. Isabelle Isoz, Ulf Persson, Kirill Volkov, Erik Johansson Nucleic acids research 2012 pols set
Recent progress in small molecule CCR5 antagonists as potential HIV-1 entry inhibitors. Wenwen Chen, Peng Zhan, Erik De Clercq, Xinyong Liu Current pharmaceutical design 2012 pols set
Regulation of the specialized DNA polymerase eta: revisiting the biological relevance of its PCNA- and ubiquitin-binding motifs. Emmanuelle Despras, Noémie Delrieu, Charlène Garandeau, Sana Ahmed-Seghir, Patricia L Kannouche Environmental and molecular mutagenesis 2012 new
β,γ-CHF- and β,γ-CHCl-dGTP diastereomers: synthesis, discrete 31P NMR signatures and absolute configurations of new stereochemical probes for DNA polymerases. Yue Wu, Valeria M Zakharova, Boris A Kashemirov, Myron F Goodman, Vinod K Batra, Samuel H Wilson, Charles E McKenna Journal of the American Chemical Society 2012 new
Design, synthesis, anti-HIV evaluation and molecular modeling of piperidine-linked amino-triazine derivatives as potent non-nucleoside reverse transcriptase inhibitors. Xuwang Chen, Peng Zhan, Xin Liu, Ziheng Cheng, Caicai Meng, Siyuan Shao, Christophe Pannecouque, Erik De Clercq, Xinyong Liu Bioorganic & medicinal chemistry 2012 pols set
RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity. Deborah L Croteau, Marie L Rossi, Chandrika Canugovi, Jane Tian, Peter Sykora, Mahesh Ramamoorthy, Zhengming Wang, Dharmendra Kumar Singh, Mansour Akbari, Rajesh Kasiviswanathan, William C Copeland, Vilhelm A Bohr Aging cell 2012 topics set
Age-dependent down-regulation of DNA polymerase δ1 in human lymphocytes. Jin-Ling Wang, Hong-Lin Guo, Pei-Chang Wang, Chen-Geng Liu Molecular and cellular biochemistry 2012 new
Molecular recognition of canonical and deaminated bases by P. abyssi family B DNA polymerase. Jérôme Gouge, Céline Ralec, Ghislaine Henneke, Marc Delarue Journal of molecular biology 2012 complete Jerome Gouge*
Diagnosis of brugian filariasis by loop-mediated isothermal amplification. Catherine B Poole, Nathan A Tanner, Yongqing Zhang, Thomas C Evans, Clotilde K S Carlow PLoS neglected tropical diseases 2012 complete Catherine B Poole*
Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase {varepsilon} in rolling circle DNA synthesis. Young-Hoon Kang, Wiebke Chemnitz Galal, A Farina, Inger Tappin, Jerard Hurwitz Proceedings of the National Academy of Sciences of the United States of America 2012 new
Model of elongation of short DNA sequence by thermophilic DNA polymerase under isothermal conditions. Tomohiro Kato, Xingguo Liang, Hiroyuki Asanuma Biochemistry 2012 complete Xingguo Liang*
Bidendate and tridendate metal-ion coordination states within ternary complexes of RB69 DNA polymerase. Shuangluo Xia, Soo Hyun Eom, William H Konigsberg, Jianhong Wang Protein science : a publication of the Protein Society 2012 topics set
Deep sequencing of the Hepatitis B Virus in Hepatocellular Carcinoma patients reveals enriched integration events, structural alterations and sequence variations. Soo Ting Toh, Yu Jin, Lizhen Liu, Jingbo Wang, Farbod Babrzadeh, Baback Gharizadeh, Mostafa Ronaghi, Han Chong Toh, Pierce Kah-Hoe Chow, Alexander Y-F Chung, London Lucien P-J Ooi, Caroline G Lee Carcinogenesis 2012 new
Inhibitory effect of novel somatostatin peptide analogues on human cancer cell growth based on the selective inhibition of DNA polymerase β Isoko Kuriyama, Anna Miyazaki, Yuko Tsuda, Hiromi Yoshida, Yoshiyuki Mizushina Bioorganic & medicinal chemistry 2012 new
Mutagenic bypass of 8-oxo-7,8-dihydroguanine (8-hydroxyguanine) by DNA polymerase κ in human cells. Hiroyuki Kamiya, Masahiro Kurokawa Chemical research in toxicology 2012 new
Effect of silencing PARG in human colon carcinoma LoVo cells on the ability of HUVEC migration and proliferation. J Pan, N J S Fauzee, Y-l Wang, Y-T Sheng, Y Tang, J-Q Wang, W-q Wu, J-x Yan, J Xu Cancer gene therapy 2012 new
DNA replication fidelity in Escherichia coli: a multi-DNA polymerase affair. Iwona J Fijalkowska, Roel M Schaaper, Piotr Jonczyk FEMS microbiology reviews 2012 new
Long-term cultivation of human corneal endothelial cells by telomerase expression. Zhiping Liu, Jing Zhuang, Chaoyang Li, Pengxia Wan, Naiyang Li, Qiang Zhou, Chenjing Zhou, Zheqian Huang, Zhichong Wang Experimental eye research 2012 topics set
Discovery of novel 2-(3-(2-chlorophenyl)pyrazin-2-ylthio)-N-arylacetamides as potent HIV-1 inhibitors using a structure-based bioisosterism approach. Peng Zhan, Wenmin Chen, Zhongjie Li, Xincang Li, Xuwang Chen, Ye Tian, Christophe Pannecouque, Erik De Clercq, Xinyong Liu Bioorganic & medicinal chemistry 2012 pols set
Synthesis, biological evaluation and molecular modeling of 4,6-diarylpyrimidines and diarylbenzenes as novel non-nucleosides HIV-1 reverse transcriptase inhibitors. Sergio R Ribone, Volker Leen, Marcela Madrid, Wim Dehaen, Dirk Daelemans, Christophe Pannecouque, Margarita C Briñón European journal of medicinal chemistry 2012 pols set
Effect of translocation defective reverse transcriptase inhibitors on the activity of n348i, a connection subdomain drug resistant hiv-1 reverse transcriptase mutant. Eleftherios Michailidis, Kamlendra Singh, Emily M Ryan, Atsuko Hachiya, Yee Tsuey Ong, Karen A Kirby, Bruno Marchand, Eiichi N Kodama, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos Cellular and molecular biology (Noisy-le-Grand, France) 2012 pols set
New Nitrogen Containing Substituents at the Indole-2-carboxamide Yield High Potent and Broad Spectrum Indolylarylsulfone HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors. Giuseppe La Regina, Antonio Coluccia, Andrea Brancale, Francesco Piscitelli, Valeria Famiglini, Sandro Cosconati, Giovanni Maga, Alberta Samuele, Emmanuel Gonzales, B Clotet, Dominique Schols, Jose Este, Ettore Novellino, Romano Silvestri Journal of medicinal chemistry 2012 pols set
Strategies for the design of HIV-1 non-nucleoside reverse transcriptase inhibitors: lessons from the development of seven representative paradigms. Dongyue Li, Peng Zhan, Erik De Clercq, Xinyong Liu Journal of medicinal chemistry 2012 pols set
KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry. Karin Betz, Denis A Malyshev, Thomas Lavergne, Wolfram Welte, Kay Diederichs, Tammy J Dwyer, Phillip Ordoukhanian, Floyd E Romesberg, Andreas Marx Nature chemical biology 2012 new
DNA polymerase beta is involved in the protection against the cytotoxicity and genotoxicity of cigarette smoke. Jie Cui, Wei Zhao, Xin Xu, Mo Yang, Yaou Ren, Zhenzhong Zhang Environmental toxicology and pharmacology 2012 new
Genomic amplification of the human telomerase gene (hTERC) associated with human papillomavirus is related to the progression of uterine cervical dysplasia to invasive cancer. Hongqian Liu, Shanling Liu, He Wang, Xiaoyan Xie, Xinlian Chen, Xuemei Zhang, Yongqing Zhang Diagnostic pathology 2012 new
Evaluation of a novel hybrid bioartificial liver based on a multi-layer flat-plate bioreactor. Xiao-Lei Shi, Yongqing Zhang, Xue-Hui Chu, Bing Han, Jin-Yang Gu, Jiang-Qiang Xiao, Jia-Jun Tan, Zhong-Ze Gu, Hao-Zhen Ren, Xian-Wen Yuan, Yi-Tao Ding World journal of gastroenterology : WJG 2012 new
Identification and expression analysis of major histocompatibility complex IIB gene in orange-spotted grouper Epinephelus coioides. D Q Lu, S B Yi, Mingzhong Yao, Y W Li, X C Liu, Yongqing Zhang, H R Lin Journal of fish biology 2012 new
Critical amino acids in Escherichia coli UmuC responsible for sugar discrimination and base-substitution fidelity. Alexandra Vaisman, Wojciech Kuban, John P McDonald, Kiyonobu Karata, Wei Wen Yang, Myron F Goodman, Roger Woodgate Nucleic acids research 2012 pols set
HIV-1 and HIV-2 Reverse Transcriptases: Different Mechanisms of Resistance to Nucleoside Reverse Transcriptase Inhibitors. Paul L Boyer, Patrick K Clark, Stephen H Hughes Journal of virology 2012 pols set
In-vitro replication studies on o(2)-methylthymidine and o(4)-methylthymidine. Nisana Andersen, Jianshuang Wang, Pengcheng Wang, Yanan Jiang, Yinsheng Wang Chemical research in toxicology 2012 new
Mouse models of DNA polymerases. Miriam Rose Menezes, Joann B Sweasy Environmental and molecular mutagenesis 2012 topics set
Synthesis, Biological Activity, and ADME Properties of Novel S-DABOs/N-DABOs as HIV Reverse Transcriptase Inhibitors. Marco Radi, Mafalda Pagano, Luigi Franchi, Daniele Castagnolo, Silvia Schenone, Gianni Casaluce, Claudio Zamperini, Elena Dreassi, Giovanni Maga, Alberta Samuele, Encarna Gonzalo, B Clotet, José A Esté, Maurizio Botta ChemMedChem 2012 pols set
A novel POLG gene mutation in a patient with SANDO. Bulent Kurt, Ali B Naini, William C Copeland, Jiesheng Lu, Salvatore DiMauro, Michio Hirano Journal of experimental and integrative medicine 2012 new
Stalled Polη at its cognate substrate initiates an alternative translesion synthesis pathway via interaction with REV1. Wakana Ito, Masayuki Yokoi, Nobutaka Sakayoshi, Yasutaka Sakurai, Jun-Ichi Akagi, Hiroshi Mitani, Fumio Hanaoka Genes to cells : devoted to molecular & cellular mechanisms 2012 new
DNA polymerase-β mediates the neurogenic effect of β-amyloid protein in cultured subventricular zone neurospheres. Marco Calafiore, Agata Copani, Wenbin Deng Journal of neuroscience research 2012 topics set
Amino acid templating mechanisms in selection of nucleotides opposite abasic sites by a family a DNA polymerase. Samra Obeid, Wolfram Welte, Kay Diederichs, Andreas Marx The Journal of biological chemistry 2012 partial results
An Interaction between DNA Polymerase and Helicase is Essential for the High Processivity of the Bacteriophage T7 Replisome. Arkadiusz W Kulczyk, Barak Akabayov, Seung-Joo Lee, Mihnea Bostina, Steven A Berkowitz, Charles C Richardson The Journal of biological chemistry 2012 partial results
A Mutation Deleting Sequences Encoding the Amino Terminus of human Cytomegalovirus UL84 impairs Interaction with UL44 and Capsid Localization. Blair L Strang, Brian J Bender, Mayuri Sharma, Jean M Pesola, Rebecca L Sanders, Deborah H Spector, Donald M Coen Journal of virology 2012 pols set
DNA polymerase ζ is a major determinant of resistance to platinum-based chemotherapeutic agents. S Sharma, Nicholas A Shah, Ariell M Joiner, Katelyn H Roberts, CE Canman Molecular pharmacology 2012 topics set
Effects of N2-Alkylguanine, O6-Alkylguanine, and Abasic Lesions on DNA Binding and Bypass Synthesis by the Euryarchaeal B-family DNA Polymerase Vent (exo-). Seonhee Lim, Insil Song, F Peter Guengerich, Jeong-Yun Choi Chemical research in toxicology 2012 topics set
Structure of human DNA polymerase iota and the mechanism of DNA synthesis. A V Makarova, A V Kulbachinskiy Biochemistry. Biokhimii͡a 2012 topics set
C-terminal extension of the yeast mitochondrial DNA polymerase determines the balance between synthesis and degradation. Katrin Viikov, Olga Jasnovidova, Tiina Tamm, Juhan Sedman PloS one 2012 partial results
DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ. Andrey G Baranovskiy, Artem G Lada, Hollie M Siebler, Yongqing Zhang, Youri I Pavlov, Tahir H Tahirov The Journal of biological chemistry 2012 new
Identification of Pold2 as a novel interaction partner of protein inhibitor of activated STAT2. Ying Zheng, Shudong Sheng, Haiyan Wang, Xiaoqing Jia, Yanqiu Hu, Yayun Qian, Yongze Zhu, Jianjun Wang International journal of molecular medicine 2012 new
Escherichia coli UmuC active site mutants: Effects on translesion DNA synthesis, mutagenesis and cell survival. Wojciech Kuban, Alexandra Vaisman, John P McDonald, Kiyonobu Karata, Wei Wen Yang, Myron F Goodman, Roger Woodgate DNA repair 2012 topics set
The catalytic cycle for ribonucleotide incorporation by human DNA Pol λ Rajendrakumar A Gosavi, Andrea F Moon, Thomas A Kunkel, Lars C Pedersen, Katarzyna Bebenek Nucleic acids research 2012 topics set
Accurate and Efficient Bypass of 8,5'-Cyclopurine-2'-Deoxynucleosides by Human and Yeast DNA Polymerase η Ashley L Swanson, Jianshuang Wang, Yinsheng Wang Chemical research in toxicology 2012 topics set
Involvement of Werner syndrome protein in MUTYH-mediated repair of oxidative DNA damage. Radhakrishnan Kanagaraj, Prasanna Parasuraman, Boris Mihaljevic, Barbara van Loon, Kamila Burdova, Christiane König, Antonia Furrer, Vilhelm A Bohr, Ulrich Hübscher, Pavel Janscak Nucleic acids research 2012 topics set
BRCT domain of DNA polymerase μ has DNA-binding activity and promotes the DNA polymerization activity. Takuro Matsumoto, Kaori Go, Mariko Hyodo, Kotaro Koiwai, So Maezawa, Takahide Hayano, Masahiro Suzuki, Osamu Koiwai Genes to cells : devoted to molecular & cellular mechanisms 2012 topics set
Multi-domain Protein Solves the Folding Problem by Multi-funnel Combined Landscape: Theoretical Investigation of a Y-Family DNA Polymerase. Yong Wang, Xiakun Chu, Zucai Suo, Erkang Wang, Jin Wang Journal of the American Chemical Society 2012 pols set
Stabilization of the Escherichia coli DNA polymerase III ε subunit by the θ subunit favors in vivo assembly of the Pol III catalytic core. Emanuele Conte, Gabriele Vincelli, Roel M Schaaper, Daniela Bressanin, Alessandra Stefan, Fabrizio Dal Piaz, Alejandro Hochkoeppler Archives of biochemistry and biophysics 2012 topics set
SARS-CoV Replication Inhibitor that Interferes with the Nucleic acid Unwinding of the Viral Helicase. Adeyemi O Adedeji, Kamalendra Singh, Nicholas E Calcaterra, Marta L Dediego, Luis Enjuanes, Susan Weiss, Stefan G Sarafianos Antimicrobial agents and chemotherapy 2012 new
Alternariol induces DNA polymerase β expression through the PKA-CREB signaling pathway. Jimin Zhao, Kangdong Liu, Jing Lu, Junfen Ma, Xiaoyan Zhang, Yanan Jiang, Hongyan Yang, Ge Jin, Guoqiang Zhao, Mingyao Zhao, Ziming Dong International journal of oncology 2012 new
HIV-1 reverse transcriptase (RT) polymorphism 172K, suppresses the effect of clinically relevant drug resistance mutations to both nucleoside and nonnucleoside RT inhibitors. Atsuko Hachiya, Bruno Marchand, Karen A Kirby, Eleftherios Michailidis, Xiongying Tu, Krzysztof Palczewski, Yee Tsuey Ong, Zhongjie Li, Daniel T Griffin, Matthew M Schuckmann, Junko Tanuma, Shinichi Oka, Kamalendra Singh, Eiichi N Kodama, Stefan G Sarafianos The Journal of biological chemistry 2012 topics set
Characterization of human DNA polymerase delta and its subassemblies reconstituted by expression in the multibac system. Yajing Zhou, Xiao Meng, Sufang Zhang, Ernest Y C Lee, Marietta Y W T Lee PloS one 2012 pols set
Biological relevance of DNA polymerase β and translesion synthesis polymerases to cancer and its treatment. Nils H Nicolay, Thomas Helleday, Ricky A Sharma Current molecular pharmacology 2012 new
Pol31 and Pol32 subunits of yeast DNA polymerase δ are also essential subunits of DNA polymerase ζ Robert E Johnson, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2012 new
Targeting DNA polymerase ß for therapeutic intervention. Eva M Goellner, David Svilar, Karen H Almeida, Robert W Sobol Current molecular pharmacology 2012 new
Escherichia coli DNA polymerase III is responsible for the high level of spontaneous mutations in mutT strains. Masami Yamada, Masatomi Shimizu, Atsushi Katafuchi, Petr Grúz, Shingo Fujii, Yukio Usui, Robert P P Fuchs, Takehiko Nohmi Molecular microbiology 2012 pols set
Active DNA unwinding dynamics during processive DNA replication. José A Morin, Francisco J Cao, José María Lázaro, J Ricardo Arias-Gonzalez, José M Valpuesta, José L Carrascosa, Margarita Salas, Borja Ibarra Proceedings of the National Academy of Sciences of the United States of America 2012 pols set
Replication bypass of the trans-4-Hydroxynonenal-derived (6S,8R,11S)-1,N(2)-deoxyguanosine DNA adduct by the sulfolobus solfataricus DNA polymerase IV. Surajit Banerjee, Plamen P Christov, Albena Kozekova, Carmelo J Rizzo, Martin Egli, Michael P Stone Chemical research in toxicology 2012 topics set
Reading DNA at single-nucleotide resolution with a mutant MspA nanopore and phi29 DNA polymerase. Elizabeth A Manrao, Ian M Derrington, Andrew H Laszlo, Kyle W Langford, Matthew K Hopper, Nathaniel Gillgren, Mikhail Pavlenok, Michael Niederweis, Jens H Gundlach Nature biotechnology 2012 pols set
Direct observation of translocation in individual DNA polymerase complexes. Joseph M Dahl, Ai H Mai, Gerald M Cherf, Nahid N Jetha, Daniel R Garalde, Andre Marziali, Mark Akeson, Hongyun Wang, Kate R Lieberman The Journal of biological chemistry 2012 pols set
Spatiotemporal recruitment of human DNA polymerase delta to sites of UV damage. Jennifer Chea, Sufang Zhang, Hong Zhao, Zhongtao Zhang, Ernest Y C Lee, Zbigniew Darzynkiewicz, Marietta Y W T Lee Cell cycle (Georgetown, Tex.) 2012 pols set
Deregulated expression of DNA polymerase β is involved in the progression of genomic instability. Qingying Luo, Yanhao Lai, Shukun Liu, Mei Wu, Yuan Liu, Zhenzhong Zhang Environmental and molecular mutagenesis 2012 new
In vivo antitumor effect of liposomes with sialyl Lewis X including monogalactosyl diacylglycerol, a replicative DNA polymerase inhibitor, from spinach. Yoshiyuki Mizushina, Takahiko Hada, Hiromi Yoshida Oncology reports 2012 topics set
DNA polymerase beta from Trypanosoma cruzi is involved in kinetoplast DNA replication and repair of oxidative lesions. Bruno Luiz Fonseca Schamber-Reis, Sheila Cristina Nardelli, Carlos Gustavo Régis-Silva, Priscila Carneiro Campos, Paula Gonçalves Cerqueira, Sabrina Almeida Lima, Glória Regina Franco, Andréa Mara Macedo, Sergio Danilo Junho Pena, Christophe Cazaux, Jean-Sébastien Hoffmann, Maria Cristina Machado Motta, Sergio Schenkman, Santuza Maria Ribeiro Teixeira, Carlos Renato Machado Molecular and biochemical parasitology 2012 pols set
DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions. Huseyin Saribasak, Robert W Maul, Zheng Cao, William W Yang, Dominik Schenten, Sven Kracker, Patricia J Gearhart The Journal of experimental medicine 2012 complete Patricia J Gearhart*
Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65. Mahavir Singh, Zhonghua Wang, Bon-Kyung Koo, Anooj Patel, Duilio Cascio, Kathleen Collins, Juli Feigon Molecular cell 2012 topics set
Temperature dependence of accuracy of DNA polymerase I from Geobacillus anatolicus. Melike Cağlayan, Neş'e Bilgin Biochimie 2012 topics set
Characterization of human DNA polymerase κ promoter in response to benzo[a]pyrene diol epoxide. Huifang Zhu, Yanfeng Fan, Jing Shen, Hongyan Qi, Jimin Shao Environmental toxicology and pharmacology 2012 topics set
A nucleotide analogue induced gain of function corrects the error-prone nature of human DNA polymerase iota. Amit Ketkar, Maroof Khan Zafar, Surajit Banerjee, Victor E Marquez, Martin Egli, Robert Lawton Eoff Journal of the American Chemical Society 2012 topics set
Simple and efficient purification of Escherichia coli DNA polymerase V: Cofactor requirements for optimal activity and processivity in vitro. Kiyonobu Karata, Alexandra Vaisman, Myron F Goodman, Roger Woodgate DNA repair 2012 topics set
Anti-Interleukin-10R1 Monoclonal Antibody Enhances Bacillus Calmette-Guérin Induced T-Helper Type 1 Immune Responses and Antitumor Immunity in a Mouse Orthotopic Model of Bladder Cancer. Nathan A Bockholt, Matthew J Knudson, Jonathan R Henning, José L Maymí, Peter Weady, George J Smith, Michael D Eisenbraun, James D Fraser, Michael E O'Donnell, Yi Luo The Journal of urology 2012 new
Single-molecule microscopy reveals new insights into nucleotide selection by DNA polymerase I. RP Markiewicz, KB Vrtis, David Rueda, Louis J Romano Nucleic acids research 2012 topics set
Identification of an Unfolding Intermediate for a DNA Lesion Bypass Polymerase. Shanen M Sherrer, Brian A Maxwell, Lindsey R Pack, Kevin A Fiala, Jason D Fowler, Jun Zhang, Zucai Suo Chemical research in toxicology 2012 topics set
Label-free electrical detection of pyrophosphate generated from DNA polymerase reactions on field-effect devices. Grace M Credo, Xing Su, Kai Wu, Oguz H Elibol, David J Liu, Bobby Reddy, Ta-Wei Tsai, Brian R Dorvel, Jonathan S Daniels, Rashid Bashir, Madoo Varma The Analyst 2012 new
Roles of the Y-family DNA polymerase Dbh in accurate replication of the Sulfolobus genome at high temperature. Cynthia J Sakofsky, Patricia L Foster, Dennis W Grogan DNA repair 2012 new
Unfavorable electrostatic and steric interactions in DNA polymerase β E295K mutant interfere with the enzyme's pathway. Yingqian Li, Chelsea L Gridley, Joachim Jaeger, Joann B Sweasy, Tamar Schlick Journal of the American Chemical Society 2012 topics set
Interferon regulatory factor 1 transactivates expression of human DNA polymerase η in response to carcinogen N-methyl-N'-nitro-N-nitrosoguanidine. Hongyan Qi, Huifang Zhu, Meng Lou, Yanfeng Fan, Hong Liu, Jing Shen, Zhongjie Li, Xue Lv, Jianzhen Shan, Lijun Zhu, Y Eugene Chin, Jimin Shao The Journal of biological chemistry 2012 new
Low fidelity bypass of O2-(3-pyridyl)-4-oxobutylthymine, the most persistent bulky adduct produced by the tobacco specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by model polymerases. Prakasha Gowda A S, Gowdahalli Krishnegowda, Zucai Suo, Shantu G Amin, Thomas E Spratt Chemical research in toxicology 2012 topics set
Selective disruption of the DNA polymerase III α-β complex by the umuD gene products. MC Silva, P Nevin, EA Ronayne, PJ Beuning Nucleic acids research 2012 topics set
A transposon-derived DNA polymerase from Entamoeba histolytica displays intrinsic strand displacement, processivity and lesion bypass. Guillermo Pastor-Palacios, Varinia López-Ramírez, Cesar S Cardona-Felix, Luis G Brieba PloS one 2012 new
Contribution of Partial Charge Interactions and Base-Stacking to the Efficiency of Primer-Extension at and beyond Abasic Sites in DNA. Shuangluo Xia, Ashwani Kumar Vashishtha, David Bulkley, Soo Hyun Eom, Jianhong Wang, William H Konigsberg Biochemistry 2012 topics set
The E288K Colon Tumor Variant of DNA Polymerase Beta Is a Sequence Specific Mutator. Drew L Murphy, Katherine A Donigan, Joachim Jaeger, Joann B Sweasy Biochemistry 2012 topics set
DNA polymerase μ is a global player in the repair of non-homologous end-joining substrates. Romain Chayot, Benjamin Montagne, Miria Ricchetti DNA repair 2012 new
Telmisartan directly ameliorates the neuronal inflammatory response to IL-1beta partly through the JNK/c-Jun and NADPH oxidase pathways. Tao Pang, Juan Wang, Julius Benicky, Enrique Sanchez-Lemus, Juan M Saavedra Journal of neuroinflammation 2012 new
Mitochondrial alteration in malignantly transformed human small airway epithelial cells induced by alpha particles. Suping Zhang, Gengyun Wen, Sarah Xl Huang, Jianrong Wang, Jian Tong, Tom K Hei International journal of cancer. Journal international du cancer 2012 new
The Pre-NH2-Terminal Domain of the Herpes Simplex Virus 1 DNA Polymerase Catalytic Subunit is Required for Efficient Viral Replication. Shariya L Terrell, Donald M Coen Journal of virology 2012 new
Rapid incorporation kinetics and improved fidelity of a novel class of 3'-OH unblocked reversible terminators. Andrew F Gardner, Jinchun Wang, Weidong Wu, Jennifer Karouby, Hong Li, Brian P Stupi, William E Jack, Megan N Hersh, Michael L Metzker Nucleic acids research 2012 topics set
Using a Fluorescent Cytosine Analogue tC(o) To Probe the Effect of the Y567 to Ala Substitution on the Preinsertion Steps of dNMP Incorporation by RB69 DNA Polymerase. Shuangluo Xia, Jeff W Beckman, Jianhong Wang, William H Konigsberg Biochemistry 2012 pols set
Transient expression and activity of human DNA polymerase iota in loach embryos. Irina V Makarova, Andrey A Kazakov, Alena V Makarova, Nella V Khaidarova, Larisa V Kozikova, Valentina V Nenasheva, Leonid V Gening, Vyacheslav Z Tarantul, Ludmila E Andreeva Biotechnology letters 2012 pols set
Genotypic characterization of herpes simplex virus DNA polymerase UL42 processivity factor. Sonia Burrel, Zaïna Aït-Arkoub, Henri Agut, David Boutolleau Antiviral research 2012 topics set
Mutations conferring resistance to viral DNA polymerase inhibitors in camelpox virus give different drug-susceptibility profiles in vaccinia virus. Sophie Duraffour, Graciela Andrei, Dimitri Topalis, Marcela Krečmerová, Jean-Marc Crance, Daniel Garin, Robert Snoeck Journal of virology 2012 topics set
DNA polymerase eta is targeted by Mdm2 for polyubiquitination and proteasomal degradation in response to ultraviolet irradiation. Yong-Sam Jung, Yingjuan Qian, Xinbin Chen DNA repair 2012 topics set
The structural basis of the kinetic mechanism of a gap-filling X-family DNA polymerase that binds Mg(2+)-dNTP before binding to DNA. Shuhei Nakane, Hirohito Ishikawa, Noriko Nakagawa, Seiki Kuramitsu, Ryoji Masui Journal of molecular biology 2012 partial results
Molecular interactions in the priming complex of bacteriophage T7. Arkadiusz W Kulczyk, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 2012 topics set
Age-related decline in DNA polymerase β activity in rat brain and tissues. V N Vyjayanti, Umakanta Swain, Kalluri Subba Rao Neurochemical research 2012 topics set
Modeling translocation dynamics of strand displacement DNA synthesis by DNA polymerase I. Ping Xie Journal of molecular modeling 2012 topics set
Structure of monoubiquitinated PCNA: Implications for DNA polymerase switching and Okazaki fragment maturation. Zhenzhong Zhang, Sufang Zhang, Szu Hua Sharon Lin, Xiaoxiao Wang, Licheng Wu, Ernest Y C Lee, Marietta Y W T Lee Cell cycle (Georgetown, Tex.) 2012 complete Zhenzhong Zhang*
Transmitted antiretroviral drug resistance and thumb subdomain polymorphisms among newly HIV-1 diagnosed patients infected with CRF01_AE and CRF07_BC virus in Guangdong Province, China. Changfu Yang, Shuyuan Liu, Taisong Zhang, Yaping Hou, Xiaoli Liu, Yun Gao, Guang Yang, Zhen Wang, Huayun Chen, Ming Li, Zhenyu Zhu AIDS research and human retroviruses 2012 topics set
Differential requirement for the N-terminal catalytic domain of the DNA polymerase ε p255 subunit in the mitotic cell cycle and the endocycle. Osamu Suyari, Mieko Kawai, Hiroyuki Ida, Hideki Yoshida, Kengo Sakaguchi, Masamitsu Yamaguchi Gene 2012 new
Altered Ig Hypermutation Pattern and Frequency in Complementary Mouse Models of DNA Polymerase ζ Activity. Janssen Daly, Katarzyna Bebenek, Danielle L Watt, Kathleen Richter, Chuancang Jiang, Ming-Lang Zhao, Madhumita Ray, William Glenn McGregor, Thomas A Kunkel, Marilyn Diaz Journal of immunology (Baltimore, Md. : 1950) 2012 topics set
HIV-1 Reverse Transcription. Wei-Shau Hu, Stephen H Hughes Cold Spring Harbor perspectives in medicine 2012 topics set
DNA Polymerase β Variant Ile260Met Generates Global Gene Expression Changes Related to Cellular Transformation. Katherine A Donigan, David Tuck, Vince Schulz, Joann B Sweasy Mutagenesis 2012 topics set
Quantitative analysis of the mutagenic potential of 1-aminopyrene-DNA adduct bypass catalyzed by Y-family DNA polymerases. Shanen M Sherrer, DJ Taggart, Lindsey R Pack, Chanchal K Malik, Ashis K Basu, Zucai Suo Mutation research 2012 topics set
Structures of dNTP Intermediate States during DNA Polymerase Active Site Assembly. Bret D Freudenthal, William A Beard, Samuel H Wilson Structure (London, England : 1993) 2012 topics set
Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. Dong Ding, Xiaoyan Lou, Dasong Hua, Wei Yu, Lisha Li, Jun Wang, Feng Gao, Na Zhao, Guoping Ren, Lanjuan Li, Biaoyang Lin PLoS genetics 2012 new
E2F1: a potential negative regulator of hTERT transcription in normal cells upon activation of oncogenic c-Myc. Yongqing Zhang, Ling Chen, Shiming Yang, Dianchun Fang Medical science monitor : international medical journal of experimental and clinical research 2012 new
Mutations in human DNA polymerase γ confer unique mechanisms of catalytic deficiency that mirror the disease severity in mitochondrial disorder patients. Christal D Sohl, Rajesh Kasiviswanathan, William C Copeland, Karen S Anderson Human molecular genetics 2012 topics set
DNA polymerase zeta generates clustered mutations during bypass of endogenous DNA lesions in Saccharomyces cerevisiae. Jana E Stone, Scott A Lujan, Thomas A Kunkel, Thomas A Kunkel Environmental and molecular mutagenesis 2012 topics set
Biochemical Mechanism of HIV-1 Resistance to Rilpivirine. Kamalendra Singh, Bruno Marchand, Devendra K Rai, Bechan Sharma, Eleftherios Michailidis, Emily M Ryan, Kayla B Matzek, Maxwell D Leslie, Ariel N Hagedorn, Zhongjie Li, Pieter R Norden, Atsuko Hachiya, Michael A. Parniak, Hong-Tao Xu, Mark A. Wainberg, Stefan G Sarafianos The Journal of biological chemistry 2012 topics set
Efficient derivation and genetic modifications of human pluripotent stem cells on engineered human feeder cell lines. Chunlin Zou, Bin-Kuan Chou, Sarah N Dowey, Kitman Tsang, Xiaosong Huang, Cyndi F Liu, Cory Smith, Jonathan Yen, Prashant Mali, Yu Alex Zhang, Linzhao Cheng, Zhaohui Ye Stem cells and development 2012 new
The PAD region in the mycobacterial DinB homologue MsPolIV exhibits positional heterogeneity. Amit Sharma, V Subramanian, Deepak T Nair Acta crystallographica. Section D, Biological crystallography 2012 topics set
Factors influencing the transfer of porcine endogenous retroviruses across the membrane in bioartificial livers. Xiao-Lei Shi, Bing Han, Jia-Jun Tan, Xianwen Yuan, Yongqing Zhang, Jiang-Qiang Xiao, Zhong-Ze Gu, Yi-Tao Ding The International journal of artificial organs 2012 new
A short adaptive path from DNA to RNA polymerases. Christopher Cozens, Vitor B Pinheiro, Alexandra Vaisman, Roger Woodgate, Philipp Holliger Proceedings of the National Academy of Sciences of the United States of America 2012 topics set
Microbiological safety of a novel bio-artificial liver support system based on porcine hepatocytes: a experimental study. Bing Han, Xiao-Lei Shi, Yongqing Zhang, Xue-Hui Chu, Jin-Yang Gu, Jiang-Qiang Xiao, Hao-Zhen Ren, Jia-Jun Tan, Zhong-Ze Gu, Yi-Tao Ding European journal of medical research 2012 new
Preferred WMSA catalytic mechanism of the nucleotidyl transfer reaction in human DNA polymerase κ elucidates error-free bypass of a bulky DNA lesion. Lee Lior-Hoffmann, Liming Wang, Shenglong Wang, Nicholas E Geacintov, Suse Broyde, Yongqing Zhang Nucleic acids research 2012 new
Catalytic Effects of Mutations of Distant Protein Residues in Human DNA Polymerase β: Theory and Experiment. Martin Klvana, Drew L Murphy, Petr Jerabek, Myron F Goodman, Arieh Warshel, Joann B Sweasy, Jan Florian Biochemistry 2012 new
Escherichia coli DNA polymerase IV (Pol IV), but not Pol II, dynamically switches with a stalled Pol III* replicase. Justin M H Heltzel, Robert W Maul, David W Wolff, Mark D Sutton Journal of bacteriology 2012 pols set
Pol β associated complex and base excision repair factors in mouse fibroblasts. Rajendra Prasad, Jason G Williams, Esther W Hou, Samuel H Wilson Nucleic acids research 2012 new
POLG mutation in a patient with cataracts, early-onset distal muscle weakness and atrophy, ovarian dysgenesis and 3-methylglutaconic aciduria. MR Bekheirnia, Weiming Zhang, T Eble, A Willis, A Shaibani, Lee-Jun C Wong, F Scaglia, SU Dhar Gene 2012 topics set
Thioredoxin, the Processivity Factor, Sequesters an Exposed Cysteine in the Thumb Domain of Bacteriophage T7 DNA Polymerase. Ngoc Quang Tran, Seung-Joo Lee, Barak Akabayov, Donald E Johnson, Charles C Richardson The Journal of biological chemistry 2012 topics set
Signal amplified strategy based on target-induced strand release coupling cleavage of nicking endonuclease for the ultrasensitive detection of ochratoxin A. Xu Hun, Fang Liu, Zhenhua Mei, Lifeng Ma, Zhouping Wang, Xiliang Luo Biosensors & bioelectronics 2012 topics set
In-fusion® cloning with vaccinia virus DNA polymerase. Chad R Irwin, Andrew Farmer, David O Willer, David H Evans Methods in molecular biology (Clifton, N.J.) 2012 pols set
DNA Polymerase β Gap-filling Translesion DNA Synthesis. Parvathi Chary, William A Beard, Samuel H Wilson, R Stephen Lloyd Chemical research in toxicology 2012 pols set
Structural basis for the interaction of a hexameric replicative helicase with the regulatory subunit of human DNA polymerase α-primase. Bo Zhou, Diana R Arnett, Xian Yu, Aaron Brewster, Gregory A Sowd, Charlies L Xie, Stefan Vila, Dahai Gai, Ellen Fanning, Xiaojiang S Chen The Journal of biological chemistry 2012 new
Inhibitory effects of catechin derivatives on mammalian DNA polymerase and topoisomerase activities and mouse one-cell zygote development. Naoko Yoshida, Isoko Kuriyama, Hiromi Yoshida, Yoshiyuki Mizushina Journal of bioscience and bioengineering 2012 new
Effects of Essential Oils from Herbal Plants and Citrus Fruits on DNA Polymerase Inhibitory, Cancer Cell Growth Inhibitory, Antiallergic, and Antioxidant Activities. Mai Mitoshi, Isoko Kuriyama, Hiroto Nakayama, Hironari Miyazato, Keiichiro Sugimoto, Yuko Kobayashi, Tomoko Jippo, Kazuki Kanazawa, Hiromi Yoshida, Yoshiyuki Mizushina Journal of agricultural and food chemistry 2012 new
Regulation of human DNA polymerase delta in the cellular responses to DNA damage. Marietta Y W T Lee, Sufang Zhang, Szu Hua Sharon Lin, Jennifer Chea, Xiaoxiao Wang, Christine Leroy, Agnes Wong, Zhongtao Zhang, Ernest Y C Lee Environmental and molecular mutagenesis 2012 pols set
Arylazolylthioacetanilide. Part 11: Design, Synthesis and Biological Evaluation of 1,2,4-Triazole Thioacetanilide Derivatives as Novel Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors. Zhongjie Li, Yuan Cao, Peng Zhan, Christophe Pannecouque, Jan Balzarini, Erik De Clercq, Xinyong Liu Medicinal chemistry (Shāriqah (United Arab Emirates)) 2012 pols set
Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides. Weina Wang, Eugene Y Wu, Homme W Hellinga, Lorena S Beese The Journal of biological chemistry 2012 new
Human telomerase reverse transcriptase (hTERT) is a novel target of the Wnt/β-catenin pathway in human cancer. Yongqing Zhang, LingLing Toh, Peishan Lau, Xueying Wang The Journal of biological chemistry 2012 new
Simultaneous multiple target detection in real-time loop-mediated isothermal amplification. Nathan A Tanner, Yongqing Zhang, Thomas C Evans BioTechniques 2012 new
[Establishment of human cardiac C protein induced experimental autoimmune myocarditis model in rat]. Li-na Han, Tie-ling Li, Guo-lei Ding, Jian-wei Liu, Yu Ding, Ya-jing Zhang Zhonghua xin xue guan bing za zhi 2012 new
Structural and Inhibition Studies of the RNase H Function of Xenotropic Murine Leukemia Virus-Related Virus Reverse Transcriptase. Karen A Kirby, Bruno Marchand, Yee Tsuey Ong, Tanyaradzwa P Ndongwe, Atsuko Hachiya, Eleftherios Michailidis, Maxwell D Leslie, Daniel V Sietsema, Tracy L Fetterly, Christopher A Dorst, Kamalendra Singh, Zhengqiang Wang, Michael A. Parniak, Stefan G Sarafianos Antimicrobial agents and chemotherapy 2012 pols set
Overexpression of DNA polymerase iota (Polι) in esophageal squamous cell carcinoma. Jundong Zhou, Shuyu Zhang, Ling Xie, Pengfei Liu, Fang Xie, Jinchang Wu, Jianping Cao, Wei-Qun Ding Cancer science 2012 topics set
Mismatch repair balances leading and lagging strand DNA replication fidelity. Scott A Lujan, Jessica S Williams, Zachary F Pursell, Amy A Abdulovic-Cui, Alan B Clark, Stephanie A Nick McElhinny, Thomas A Kunkel PLoS genetics 2012 new
Overexpression of DNA polymerase zeta reduces the mitochondrial mutability caused by pathological mutations in DNA polymerase gamma in yeast. Enrico Baruffini, Fausta Serafini, Iliana Ferrero, Tiziana Lodi PloS one 2012 new
Hyperactivation of PARP Triggers Nonhomologous End-Joining in Repair-Deficient Mouse Fibroblasts. Natalie R Gassman, Donna F Stefanick, Padmini S Kedar, Julie K Horton, Samuel H Wilson PloS one 2012 new
Single-molecule Förster resonance energy transfer reveals an innate fidelity checkpoint in DNA polymerase I. Svitlana Y Berezhna, JP Gill, Rajan Lamichhane, David P Millar Journal of the American Chemical Society 2012 pols set
Interaction between Escherichia coli DNA polymerase IV and single-stranded DNA-binding protein is required for DNA synthesis on SSB-coated DNA. Asako Furukohri, Yoshito Nishikawa, Masahiro Tatsumi Akiyama, Hisaji Maki Nucleic acids research 2012 pols set
Effect of β,γ-CHF- and β,γ-CHCl-dGTP Halogen Atom Stereochemistry on the Transition State of DNA Polymerase β Keriann Oertell, Yue Wu, Valeria M Zakharova, Boris A Kashemirov, David D Shock, William A Beard, Samuel H Wilson, Charles E McKenna, Myron F Goodman Biochemistry 2012 new
DNA polymerase delta in dna replication and genome maintenance. Marc J Prindle, Lawrence A Loeb Environmental and molecular mutagenesis 2012 new
Silencing of human DNA polymerase λ causes replication stress and is synthetically lethal with an impaired S phase checkpoint. Elisa Zucca, Federica Bertoletti, Ursula Wimmer, Elena Ferrari, Giuliano Mazzini, Svetlana V Khoronenkova, Nicole Grosse, Barbara van Loon, Grigory L Dianov, Ulrich Hübscher, Giovanni Maga Nucleic acids research 2012 new
Human DNA polymerase β, but not λ, can bypass a 2-deoxyribonolactone lesion together with proliferating cell nuclear antigen. Emmanuele Crespan, Emanuela Pasi, Shuhei Imoto, Ulrich Hübscher, Marc M Greenberg, Giovanni Maga ACS chemical biology 2012 new
My life with bacteriophage O29. Margarita Salas The Journal of biological chemistry 2012 new
The essential role of the 3' terminal template base in the first steps of protein-primed DNA replication. Irene Rodríguez, Elisa Longás, Miguel de Vega, Margarita Salas PloS one 2012 new
A four-subunit DNA polymerase ζ complex containing Pol δ accessory subunits is essential for PCNA-mediated mutagenesis. Alena V Makarova, Joseph L Stodola, Peter M J Burgers Nucleic acids research 2012 new
Human DNA Polymerase {epsilon} Is Able to Efficiently Extend from Multiple Consecutive Ribonucleotides. A Yasemin Goksenin, Walter J Zahurancik, Kimberly G Lecompte, DJ Taggart, Zucai Suo, Zachary F Pursell The Journal of biological chemistry 2012 new
DNA polymerase α (swi7) and the flap endonuclease Fen1 (rad2) act together in the S-phase alkylation damage response in S. pombe. Milana Koulintchenko, Sonya Vengrova, Trevor Eydmann, Prakash Arumugam, Jacob Z Dalgaard PloS one 2012 topics set
[Mutation analysis of the HBV reverse transcriptase in nucleos(t)ide-treated patients with chronic HBV infection]. Xiu-Juan Jiao, Xun Peng, Xiu-Min Jiao, Jin-Sheng Wang, Xie-Wen Sun, Pei-Li Zhao, Shou-Yun Wang, Jia-Qun Liu, Tong Li, Jing-Xian Yang Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 2012 topics set
Dynamics of the translocation step measured in individual DNA polymerase complexes. Kate R Lieberman, Joseph M Dahl, Ai H Mai, Mark Akeson, Hongyun Wang Journal of the American Chemical Society 2012 topics set
Recent advances in thymidine kinase 2 (TK2) inhibitors and new perspectives for potential applications. Eva-María Priego, Anna Karlsson, Federico Gago, María-José Camarasa, Jan Balzarini, María-Jesús Pérez-Pérez Current pharmaceutical design 2012 pols set
Thermostable DNA polymerase from a viral metagenome is a potent RT-PCR enzyme. Michael J Moser, Robert A DiFrancesco, Krishne Gowda, Audrey J Klingele, Darby R Sugar, Stacy Stocki, David A Mead, Thomas W Schoenfeld PloS one 2012 new
Dihydro-alkoxyl-benzyl-oxopyrimidine derivatives (DABOs) as non-nucleoside reverse transcriptase inhibitors: an update review (2001-2011). Shiqiong Yang, Fen-Er Chen, Erik De Clercq Current medicinal chemistry 2012 pols set
A conserved motif in the C-terminal tail of DNA polymerase α tethers primase to the eukaryotic replisome. Mairi L Kilkenny, Giacomo De Piccoli, Rajika L Perera, Karim Labib, Luca Pellegrini The Journal of biological chemistry 2012 new
A germline polymorphism of DNA polymerase Beta induces genomic instability and cellular transformation. Jennifer Yamtich, Antonia A Nemec, Agnes Keh, Joann B Sweasy PLoS genetics 2012 new
HIV-1 reverse transcriptase complex with DNA and nevirapine reveals non-nucleoside inhibition mechanism. Kalyan Das, Sergio E Martinez, Joseph David Bauman, Edward Arnold Nature structural & molecular biology 2012 topics set
Comparison of two POLQ mutants reveals that a polymerase-inactive POLQ retains significant function in tolerance to etoposide and γ-irradiation in mouse B cells. Yingqian Li, Xiang Gao, Ji-Yang Wang Genes to cells : devoted to molecular & cellular mechanisms 2011 new
Non-nucleosidic inhibition of Herpes simplex virus DNA polymerase: mechanistic insights into the anti-herpetic mode of action of herbal drug withaferin A. Abhinav Grover, Vibhuti Agrawal, Ashutosh Shandilya, Virendra S Bisaria, Durai Sundar BMC bioinformatics 2011 topics set
Mitochondrial DNA polymerase {gamma} mutations: an ever expanding molecular and clinical spectrum. Sha Tang, Jing Wang, Ni-Chung Lee, Margherita Milone, Michelle C Halberg, Eric S Schmitt, William J Craigen, Weiming Zhang, Lee-Jun C Wong Journal of medical genetics 2011 new
The effect of aging on the DNA damage and repair capacity in 2BS cells undergoing oxidative stress. Jin-Ling Wang, Pei-Chang Wang Molecular biology reports 2011 new
Antimutator alleles of yeast DNA polymerase gamma modulate the balance between DNA synthesis and excision. Françoise Foury, Karolina Szczepanowska PloS one 2011 topics set
Increased Platelet Reactivity in HIV-1-Infected Patients Receiving Abacavir-Containing Antiretroviral Therapy. Claudette S Satchell, Jane A O'Halloran, Aoife G Cotter, Aaron J Peace, Eileen F O'Connor, Anthony F Tedesco, Eoin R Feeney, John S Lambert, Gerard J Sheehan, Dermot Kenny, Patrick W G Mallon The Journal of infectious diseases 2011 topics set
Nucleosome Disruption by DNA Ligase III-XRCC1 Promotes Efficient Base Excision Repair. Ian D Odell, Joy-El Barbour, Drew L Murphy, Julie A Della Maria, Joann B Sweasy, Alan E Tomkinson, Susan S Wallace, David S Pederson Molecular and cellular biology 2011 complete David S Pederson*
A functional tandem-repeats polymorphism in the downstream of TERT is associated with the risk of nasopharyngeal carcinoma in Chinese population. Yang Zhang, Hongxing Zhang, Yun Zhai, Zhifu Wang, Fuchao Ma, Hongxue Wang, Peiyao Li, Ying Zhang, Lixia Yu, Ying Cui, Fuchu He, Gangqiao Zhou BMC medicine 2011 topics set
REV1 and polymerase {zeta} facilitate homologous recombination repair. S Sharma, JK Hicks, CL Chute, JR Brennan, JY Ahn, TW Glover, CE Canman Nucleic acids research 2011 topics set
Dehydroaltenusin is a specific inhibitor of mammalian DNA polymerase α Yoshiyuki Mizushina, Naoki Maeda, Isoko Kuriyama, Hiromi Yoshida Expert opinion on investigational drugs 2011 topics set
[The prevalence of HIV-1 drug resistance and associated factors in AIDS patients receiving HAART in Zhecheng county, Henan province]. Yuan Yuan, Hui Xing, Xiao-Yu Wang, Chun-hua Liu, Li-Ting Yang, Ben-Feng Zheng, Xia Wang, Yu-Hua Ruan, Zhe Wang, Hong-wei Liu, Yi-ming Shao Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 2011 pols set
hTERT promoter methylation and telomere length in childhood acute lymphoblastic leukemia - associations with immunophenotype and cytogenetic subgroup. M Borssen, I Cullman, U Noren-Nystrom, C Sundstrom, A Porwit, E Forestier, G Roos Experimental hematology 2011 topics set
Structural Insights into Complete Metal Ion Coordination from Ternary Complexes of B Family RB69 DNA Polymerase. Shuangluo Xia, Michael Wang, Gregor Blaha, William H Konigsberg, Jianhong Wang Biochemistry 2011 pols set
Mechanism of interaction of novel indolylarylsulfone derivatives with K103N and Y181I mutant HIV-1 reverse transcriptase in complex with its substrates. Alberta Samuele, Sara Bisi, Alexandra Kataropoulou, Giuseppe La Regina, Francesco Piscitelli, Valerio Gatti, Romano Silvestri, Giovanni Maga Antiviral chemistry & chemotherapy 2011 pols set
dnaX36 Mutator of Escherichia coli: effects of the {tau} subunit of the DNA polymerase III holoenzyme on chromosomal DNA replication fidelity. Damian Gawel, Piotr Jonczyk, I Fijalkowska, Roel M Schaaper J Bacteriol 2011 new
Lesion bypass activity of DNA polymerase theta (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts. Matthew Hogg, Masayuki Seki, Richard D Wood, Sylvie Doublié, Susan S Wallace Journal of molecular biology 2011 new
Bypass of a nick by the replisome of bacteriophage T7. B Zhu, Seung-Joo Lee, Charles C Richardson The Journal of biological chemistry 2011 complete Charles C Richardson*, Bin Zhu*
DNA polymerase ι of mammals as a participant in translesion synthesis of DNA. Leonid V Gening Biochemistry. Biokhimii͡a 2011 topics set
3-Hydroxypyrimidine-2,4-diones as an inhibitor scaffold of HIV integrase. Jing Tang, Kasthuraiah Maddali, Mathieu Metifiot, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang Journal of medicinal chemistry 2011 pols set
[Identification the relationship between mutation patterns of rtM204I/V in the polymerase gene and genotypes of hepatitis B virus]. Li Yan, Lei Xiao, Jun-Feng Wei, Jian Sun, Zhan-hui Wang, Jin-lin Hou Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 2011 pols set
Loop-mediated isothermal amplification: rapid detection of Angiostrongylus cantonensis infection in Pomacea canaliculata. Rui Chen, QunBo Tong, Yongqing Zhang, Di Lou, QingMing Kong, Shan Lv, MingMing Zhuo, LiYong Wen, ShaoHong Lu Parasites & vectors 2011 new
Drug-sensitive DNA Polymerase {delta} Reveals a Role for Mismatch Repair in Checkpoint Activation in Yeast. Linda J Reha-Krantz, Md Shahjahan P Siddique, Kelly M Murphy, Andrea Tam, Michelle O'Carroll, Sam Lou, Amy Schultz, Charles Boone Genetics 2011 pols set
One-year monthly survey of rotavirus, astrovirus and norovirus in three sewage treatment plants in Beijing, China and associated health risk assessment. Xiao Q He, Li Cheng, D Y Zhang, Xiang M Xie, D H Wang, Zhengqiang Wang Water science and technology : a journal of the International Association on Water Pollution Research 2011 new
Characterization of the elongation complex of dengue virus RNA polymerase: assembly, kinetics of nucleotide incorporation, and fidelity. Zhinan Jin, Jerome Deval, Kenneth A Johnson, David C Swinney The Journal of biological chemistry 2011 pols set
Tumor-specific expression of microRNA-26a suppresses human hepatocellular carcinoma growth via cyclin-dependent and -independent pathways. Lizao Chen, Jianming Zheng, Yongqing Zhang, Luxi Yang, Jiaqi Wang, Jian Ni, Daxiang Cui, Chaoqin Yu, Zailong Cai Molecular therapy : the journal of the American Society of Gene Therapy 2011 new
Identification and expression of a putative LPS-induced TNF-α factor from Asiatic hard clam Meretrix meretrix. Hong-Jun Li, Qing Yang, Xiang-Gang Gao, Hao Su, Juan Wang, Chong-Bo He Molecular biology reports 2011 new
Effects of quinone derivatives, such as 1,4-naphthoquinone, on DNA polymerase inhibition and anti-inflammatory action. Kazuki Kobayashi, Shin Nishiumi, Masayuki Nishida, Midori Hirai, Takeshi Azuma, Hiromi Yoshida, Yoshiyuki Mizushina, Masaru Yoshida Medicinal chemistry (Shāriqah (United Arab Emirates)) 2011 topics set
Screening and identification of specific markers for bladder transitional cell carcinoma from urine urothelial cells with suppressive subtractive hybridization and cDNA microarray. Baihong Guo, Tuanjie Che, Baoguang Shi, Lijun Guo, Yongsheng Yin, Lin Li, Jinming Wang, Dongwen Yan, Yirong Chen Canadian Urological Association journal = Journal de l'Association des urologues du Canada 2011 new
Ultra-sensitive DNA assay based on single-molecule detection coupled with fluorescent quantum dot-labeling and its application to determination of messenger RNA. Li Li, Xincang Li, Lu Li, Jinxing Wang, Wenrui Jin Analytica chimica acta 2011 new
The sugar ring conformation of 4'-ethynyl-2-fluoro-2'-deoxyadenosine and its recognition by the polymerase active site of HIV reverse transcriptase. Karen A Kirby, Kamalendra Singh, Eleftherios Michailidis, Bruno Marchand, Eiichi N Kodama, Noriyuki Ashida, Hiroyuki Mitsuya, Michael A. Parniak, Stefan G Sarafianos Cellular and molecular biology (Noisy-le-Grand, France) 2011 pols set
[Genotypic resistance mutations to antiretroviral drugs in newly confirmed human immunodeficiency virus infectors in Beijing]. Jing-Rong Ye, Lei Guo, Hong-Yan Lu, Ruo-Lei Xin, Yi Zeng Zhonghua yi xue za zhi 2011 topics set
Foamy retrovirus integrase contains a Pol dimerization domain required for protease activation. Eun-Gyung Lee, Jacqueline Roy, Dana Jackson, Patrick K Clark, Paul L Boyer, Stephen H Hughes, Maxine L Linial Journal of virology 2011 new
Yeast mitochondrial DNA polymerase is a highly processive single-subunit enzyme. Katrin Viikov, Priit Väljamäe, Juhan Sedman Mitochondrion 2011 complete Juhan Sedman*
Anti-cancer effect of spinach glycoglycerolipids as angiogenesis inhibitors based on the selective inhibition of DNA polymerase activity. Naoki Maeda, Kiminori Matsubara, Hiromi Yoshida, Yoshiyuki Mizushina Mini reviews in medicinal chemistry 2011 new
Broad-spectrum aptamer inhibitors of HIV reverse transcriptase closely mimic natural substrates. Mark A Ditzler, Debojit Bose, Nikolozi Shkriabai, Bruno Marchand, Stefan G Sarafianos, Mamuka Kvaratskhelia, Donald H Burke Nucleic acids research 2011 pols set
Relaxed complex scheme suggests novel inhibitors for the lyase activity of DNA polymerase beta. Khaled H Barakat, Jack A Tuszynski Journal of molecular graphics & modelling 2011 topics set
Mitochondrial DNA replication and disease: insights from DNA polymerase gamma mutations. Jeffrey D Stumpf, William C Copeland Cell Mol Life Sci 2011 new
Polymerase Chaperoning and Multiple ATPase Sites Enable the E. coli DNA Polymerase III Holoenzyme to Rapidly Form Initiation Complexes. Christopher D Downey, Elliott Crooke, Charles S McHenry Journal of molecular biology 2011 pols set
Site-directed mutagenesis of the χ subunit of DNA polymerase III and single-stranded DNA-binding protein of E. coli reveals key residues for their interaction. Natalie Naue, Roman Fedorov, Andreas Pich, Dietmar J Manstein, Ute Curth Nucleic acids research 2011 pols set
Crystal structure of tert-butyldimethylsilyl-spiroaminooxathioledioxide-thymine (TSAO-T) in complex with HIV-1 reverse transcriptase (RT) redefines the elastic limits of the non-nucleoside inhibitor-binding pocket. Kalyan Das, Joseph David Bauman, Angela S Rim, Chhaya Dharia, Arthur D Clark, María-José Camarasa, Jan Balzarini, Edward Arnold Journal of medicinal chemistry 2011 complete Kalyan Das*
Learning from Directed Evolution: Thermus aquaticus DNA Polymerase Mutants with Translesion Synthesis Activity. Samra Obeid, Andreas Schnur, Christian Gloeckner, Nina Blatter, Wolfram Welte, Kay Diederichs, Andreas Marx Chembiochem : a European journal of chemical biology 2011 complete Andreas Marx*
DNA polymerase activity at the single-molecule level. JP Gill, J Wang, David P Millar Biochemical Society transactions 2011 new
Metal-induced DNA translocation leads to DNA polymerase conformational activation. Thomas W Kirby, Eugene F DeRose, Nisha A Cavanaugh, William A Beard, David D Shock, Geoffrey A Mueller, Samuel H Wilson, Robert E London Nucleic acids research 2011 new
The Y-family DNA polymerase Dpo4 uses a template slippage mechanism to create single-base deletions. Yifeng Wu, Ryan C Wilson, Janice D Pata Journal of bacteriology 2011 new
Improved thermostability and PCR efficiency of Thermococcus celericrescens DNA polymerase via site-directed mutagenesis. Kee Pum Kim, Sung Suk Cho, Kang Keun Lee, Man Hui Youn, Suk-Tae Kwon Journal of biotechnology 2011 new
Pirh2 E3 ubiquitin ligase monoubiquitinates DNA polymerase eta to suppress translesion DNA synthesis. Yong-Sam Jung, Anne Hakem, Razqallah Hakem, Xinbin Chen Molecular and cellular biology 2011 new
Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase α. Jia Sun, Yuting Yang, Ke Wan, Ninghui Mao, Tai-Yuan Yu, Yi-Chien Lin, Diane C DeZwaan, Brian C Freeman, Jing-Jer Lin, Neal F Lue, Ming Lei Cell research 2011 new
USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA polymerase β. Jason L Parsons, Irina I Dianova, Svetlana V Khoronenkova, Mariola J Edelmann, Benedikt M Kessler, Grigory L Dianov Molecular cell 2011 topics set
Sensing of replication stress and Mec1 activation act through two independent pathways involving the 9-1-1 complex and DNA polymerase ε. Fabio Puddu, Gabriele Piergiovanni, Paolo Plevani, Marco Muzi-Falconi PLoS genetics 2011 new
Replication of ribonucleotide-containing DNA templates by yeast replicative polymerases. Danielle L Watt, Erik Johansson, Peter M J Burgers, Thomas A Kunkel DNA repair 2011 new
Molecular detection of persistent postoperative circulating tumour cells in stages II and III colon cancer patients via multiple blood sampling: prognostic significance of detection for early relapse. C-Y Lu, Y-H Uen, H-L Tsai, S-C Chuang, M-F Hou, D-C Wu, S-H Hank Juo, S-R Lin, J-Y Wang British journal of cancer 2011 new
Distinct complexes of DNA polymerase I (Klenow fragment) for base and sugar discrimination during nucleotide substrate selection. Daniel R Garalde, Christopher A Simon, Joseph M Dahl, Hongyun Wang, Mark Akeson, Kate R Lieberman The Journal of biological chemistry 2011 complete Kate R Lieberman*
A top-down view on DNA replication and recombination from 9,000 feet above sea level. Erik Johansson, Christian Speck, Andrei Chabes Genome biology 2011 new
Role of human DNA polymerase κ in extension opposite from a cis-syn thymine dimer. Rodrigo Vasquez-Del Carpio, Timothy D Silverstein, Samer Lone, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Journal of molecular biology 2011 topics set
DNA polymerase beta is critical for genomic stability of sperm cells. Dawit Kidane, Shibani Dalal, Agnes Keh, Yanfeng Liu, Daniel Zelterman, Joann B Sweasy DNA repair 2011 new
Replication infidelity via a mismatch with Watson-Crick geometry. Katarzyna Bebenek, Lars C Pedersen, Thomas A Kunkel Proceedings of the National Academy of Sciences of the United States of America 2011 topics set
Biochemical behavior of N-oxidized cytosine and adenine bases in DNA polymerase-mediated primer extension reactions. Hirosuke Tsunoda, Tomomi Kudo, Yoshiaki Masaki, Akihiro Ohkubo, Kohji Seio, Mitsuo Sekine Nucleic acids research 2011 topics set
Structural mechanism of ribonucleotide discrimination by a Y-family DNA polymerase. Kevin N Kirouac, Zucai Suo, Hong Ling Journal of molecular biology 2011 topics set
Sequence-specific stalling of DNA polymerase γ and the effects of mutations causing progressive ophthalmoplegia. Neli Atanassova, Javier Miralles Fusté, Sjoerd Wanrooij, Bertil Macao, Steffi Goffart, Stefan Bäckström, Geraldine Farge, Ivan Khvorostov, Nils-Göran Larsson, Johannes N Spelbrink, Maria Falkenberg Human molecular genetics 2011 topics set
AtPolλ, a homolog of mammalian DNA polymerase λ in Arabidopsis thaliana, is involved in the repair of UV-B induced DNA damage through the dark repair pathway. Sujit Roy, Swarup Roy Choudhury, Sanjay Kumar Singh, Kali Pada Das Plant & cell physiology 2011 topics set
A phage-encoded inhibitor of Escherichia coli DNA replication targets the DNA polymerase clamp loader. Sho T Yano, Lucia B Rothman-Denes Molecular microbiology 2011 topics set
Structure of the SSB-DNA polymerase III interface and its role in DNA replication. Aimee H Marceau, Soon Bahng, Shawn C Massoni, Nicholas P George, Steven J Sandler, Kenneth J Marians, James L Keck The EMBO journal 2011 new
A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase beta. De-Sheng Pei, Xiao-Jie Yang, Wei Liu, Jeroen E J Guikema, Carol E Schrader, Phyllis R Strauss Nucleic acids research 2011 new
Engineered split in Pfu DNA polymerase fingers domain improves incorporation of nucleotide gamma-phosphate derivative. Connie J Hansen, Lydia Wu, Jeffrey D Fox, Bahram Arezi, Holly H Hogrefe Nucleic acids research 2011 complete
Partial sequence of the DNA-dependent DNA polymerase gene of fowl adenoviruses: a reference panel for a general diagnostic PCR in poultry. Gyozo L Kaján, Soroush Sameti, Mária Benko Acta veterinaria Hungarica 2011 complete Gyozo L Kaján*
Mismatch repair causes the dynamic release of an essential DNA polymerase from the replication fork. Andrew D Klocko, Jeremy W Schroeder, Brian W Walsh, Justin S Lenhart, Margery L Evans, Lyle A Simmons Molecular microbiology 2011 topics set
Interaction of gold nanoparticles with Pfu DNA polymerase and effect on polymerase chain reaction. L-P Sun, S Wang, Z-W Zhang, Y-Y Ma, Y-Q Lai, J Weng, Q-Q Zhang IET nanobiotechnology / IET 2011 pols set
Binding of Mn-deoxyribonucleoside triphosphates to the active site of the DNA polymerase of bacteriophage T7. Barak Akabayov, Charles C Richardson Powder diffraction 2011 new
Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures. Shuangluo Xia, Michael Wang, Harold R Lee, Arjun Sinha, Gregor Blaha, Thomas David Christian, Jianhong Wang, William H Konigsberg Journal of molecular biology 2011 topics set
How a DNA polymerase clamp loader opens a sliding clamp. Brian A Kelch, Debora L Makino, Mike E O'Donnell, John Kuriyan Science (New York, N.Y.) 2011 topics set
Mutagenesis of the human immunodeficiency virus reverse transcriptase p51 subunit defines residues contributing to vinylogous urea inhibition of Ribonuclease H activity. Suhman Chung, Jennifer T Miller, Barry C Johnson, Stephen H Hughes, Stuart F J Le Grice The Journal of biological chemistry 2011 pols set
An Abridged Transition State Model To Derive Structure, Dynamics, and Energy Components of DNA Polymerase β Fidelity. Martin Klvaňa, Petr Jeřábek, Myron F Goodman, Jan Florián Biochemistry 2011 new
Reduced stimulation of recombinant Pol {gamma} and mtDNA helicase by variants of mitochondrial single-stranded DNA-binding protein (mtSSB) correlates with defects in mtDNA Replication in animal cells. Marcos T Oliveira, Laurie S Kaguni The Journal of biological chemistry 2011 pols set
Molecular regulation of telomerase activity in aging. Craig Nicholls, He Li, Jian-Qiu Wang, Jun-Ping Liu Protein & cell 2011 pols set
Hydrogen-bonding capability of a templating difluorotoluene nucleotide residue in an RB69 DNA polymerase ternary complex. Shuangluo Xia, William H Konigsberg, Jianhong Wang Journal of the American Chemical Society 2011 topics set
The Mechanism of Interaction of Human Mitochondrial DNA Polymerase γ with the Novel Nucleoside Reverse Transcriptase Inhibitor 4' -Ethynyl-2-Fluoro-2' -Deoxyadenosine Indicates a Low Potential for Host Toxicity. Christal D Sohl, Kamlendra Singh, Rajesh Kasiviswanathan, William C Copeland, Hiroyuki Mitsuya, Stefan G Sarafianos, Karen S Anderson Antimicrobial agents and chemotherapy 2011 new
A novel "eukaryote-made" thermostable DNA polymerase which is free from bacterial DNA contamination. H Niimi, M Mori, H Tabata, H Minami, Takayuki Ueno, S Hayashi, I Kitajima Journal of clinical microbiology 2011 topics set
N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide. Jiang-bo Tang, David Svilar, Ram N Trivedi, Xiao-Hong Wang, Eva M Goellner, Briana Moore, Ronald L Hamilton, Lauren A Banze, Ashley R Brown, Robert W Sobol Neuro-oncology 2011 topics set
Single-nucleotide base excision repair DNA polymerase activity in C. elegans in the absence of DNA polymerase {beta} Kenjiro Asagoshi, Wade Lehmann, Elena K Braithwaite, Lucas Santana-Santos, Rajendra Prasad, Jonathan H Freedman, Bennett Van Houten, Samuel H Wilson Nucleic acids research 2011 new
Growth inhibition and chromosomal instability of cultured marsupial (opossum) cells after treatment with DNA polymerase α inhibitor. Masaharu Takemura, Tomoko Kazama, Kurumi Sakuma, Yoshiyuki Mizushina, Teruyoshi Oshima Bioscience, biotechnology, and biochemistry 2011 new
Identification of alternative binding sites for inhibitors of HIV-1 ribonuclease H through comparative analysis of virtual enrichment studies. Anthony K Felts, Krystal Labarge, Joseph David Bauman, Dishaben V Patel, Daniel M Himmel, Edward Arnold, Michael A. Parniak, Ronald M Levy Journal of chemical information and modeling 2011 pols set
Hsp12.6 expression is inducible by host immunity in adult worms of the parasitic nematode Nippostrongylus brasiliensis. Naoki Arizono, Masami Yamada, Tatsuya Tegoshi, Yutaka Takaoka, Mika Ohta, Toshiyuki Sakaeda PloS one 2011 new
In situ labeling of DNA breaks and apoptosis by T7 DNA polymerase. Vladimir V Didenko Methods in molecular biology (Clifton, N.J.) 2011 pols set
Synthesis, activity, and structural analysis of novel α-hydroxytropolone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H. Suhman Chung, Daniel M Himmel, Jian-Kang Jiang, Krzysztof Wojtak, Joseph David Bauman, Jason W Rausch, Jennifer A Wilson, John A Beutler, Craig J Thomas, Edward Arnold, Stuart F J Le Grice Journal of medicinal chemistry 2011 pols set
Human Cytomegalovirus UL44 Concentrates at the Periphery of Replication Compartments, the Site of Viral DNA Synthesis. Blair L Strang, Steeve Boulant, Lynne Chang, David M Knipe, Tomas Kirchhausen, Donald M Coen Journal of virology 2011 new
Functional analysis of light-regulated promoter region of AtPolλ gene. Sujit Roy, Swarup Roy Choudhury, Sanjay Kumar Singh, Kali Pada Das Planta 2011 new
Discovery of cyanophage genomes which contain mitochondrial DNA polymerase. Yi-Wah Chan, Remus Mohr, Andrew D Millard, Antony B Holmes, Anthony W Larkum, Anna L Whitworth, Nicholas H Mann, David J Scanlan, Wolfgang R Hess, Martha R J Clokie Molecular biology and evolution 2011 new
Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers. Rajesh Kasiviswanathan, Margaret A Gustafson, William C Copeland, Joel N Meyer The Journal of biological chemistry 2011 partial results
Cyclopropavir Susceptibility of Cytomegalovirus DNA Polymerase Mutants Selected after Antiviral Drug Exposure. Sunwen Chou, Gail Marousek, T L Bowlin Antimicrobial agents and chemotherapy 2011 topics set
Links between DNA polymerase beta expression and sensitivity to bleomycin. Shukun Liu, Yanhao Lai, Wei Zhao, Mei Wu, Zhenzhong Zhang Toxicology 2011 topics set
Coronavirus infection induces DNA replication stress partly through interaction of its nonstructural protein 13 with the p125 subunit of DNA polymerase δ. Ling Hui Xu, Mei Huang, Shou Guo Fang, Ding Xiang Liu The Journal of biological chemistry 2011 pols set
Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination. Enni Markkanen, Barbara van Loon, Elena Ferrari, Jason L Parsons, Grigory L Dianov, Ulrich Hübscher Proceedings of the National Academy of Sciences of the United States of America 2011 topics set
The interface of transcription and DNA replication in the mitochondria. Rajesh Kasiviswanathan, Tammy R L Collins, William C Copeland Biochimica et biophysica acta 2011 new
Molecular architecture of a multifunctional MCM complex. June Sanchez-Berrondo, Pablo Mesa, Arkaitz Ibarra, Maria I Martínez-Jiménez, Luis Blanco, Juan Méndez, Jasminka Boskovic, Guillermo Montoya Nucleic acids research 2011 complete Guillermo Montoya*
The biochemistry and fidelity of synthesis by the apicoplast genome replication DNA polymerase Pfprex from the malaria parasite Plasmodium falciparum. Scott R Kennedy, Cheng-Yao Chen, Michael W Schmitt, Cole N Bower, Lawrence A Loeb Journal of molecular biology 2011 topics set
The Rate of Polymerase Release upon Filling the Gap between Okazaki Fragments Is Inadequate to Support Cycling during Lagging Strand Synthesis. Paul R Dohrmann, Carol M Manhart, Christopher D Downey, Charles S McHenry Journal of molecular biology 2011 partial results
Molecular modelling studies of new potential human DNA polymerase α inhibitors. Barbara Zdrazil, Anja Schwanke, Birte Schmitz, Monika Schäfer-Korting, Hans-Dieter Höltje Journal of enzyme inhibition and medicinal chemistry 2011 topics set
Lesion bypass by S. cerevisiae Pol ζ alone. JanaE Stone, Dinesh Kumar, SaraK Binz, Aki Inase, Shigenori Iwai, Andrei Chabes, PeterM Burgers, ThomasA Kunkel DNA repair 2011 new
Phenotypic diversity of cytomegalovirus DNA polymerase gene variants observed after antiviral therapy. Sunwen Chou Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2011 complete Sunwen Chou*
Oxidative DNA damage bypass in Arabidopsis thaliana requires DNA polymerase λ and proliferating cell nuclear antigen 2. Alessandra Amoroso, Lorenzo Concia, Caterina Maggio, Cécile Raynaud, Catherine Bergounioux, Emmanuele Crespan, Rino Cella, Giovanni Maga The Plant cell 2011 topics set
Inaccurate DNA synthesis in cell extracts of yeast producing active human DNA polymerase iota. Alena V Makarova, Corinn Grabow, Leonid V Gening, Vyacheslav Z Tarantul, Tahir H Tahirov, Tadayoshi Bessho, Youri I Pavlov PloS one 2011 pols set
Promiscuous DNA synthesis by human DNA polymerase θ M Hogg, AE Sauer-Eriksson, Erik Johansson Nucleic acids research 2011 topics set
Absence of biallelic TCRγ deletion predicts induction failure and poorer outcomes in childhood T-cell acute lymphoblastic leukemia. Yung-Li Yang, Chih-Cheng Hsiao, Hsuan-Yu Chen, Kai-Hsin Lin, Shiann-Tarng Jou, Jiann-Shiuh Chen, Te-Kau Chang, Jiunn-Ming Sheen, Sung-Liang Yu, Meng-Yao Lu, Chao-Neng Cheng, Kang-Hsi Wu, Shih-Chung Wang, Jiaan-Der Wang, Hsiu-Hao Chang, Shu-Rung Lin, Shu-Wha Lin, Dong-Tsamn Lin Pediatric blood & cancer 2011 new
Bypass of N²-ethylguanine by human DNA polymerase κ. Matthew G Pence, Patrick Blans, Charles N Zink, James C Fishbein, Fred W Perrino DNA repair 2011 topics set
Small Molecule Inhibitors of Human DNA Polymerase λ. Tobias Strittmatter, Bettina Bareth, Timo A Immel, Thomas Huhn, Thomas U Mayer, Andreas Marx ACS chemical biology 2011 topics set
Acylated catechin derivatives: inhibitors of DNA polymerase and angiogenesis. Yoshiyuki Mizushina, Akiko Saito, Keiko Horikawa, Noriyuki Nakajima, Akira Tanaka, Hiromi Yoshida, Kiminori Matsubara Frontiers in bioscience (Elite edition) 2011 new
Human DNA Polymerase η Is Pre-Aligned for dNTP Binding and Catalysis. Ajay Ummat, Timothy D Silverstein, Rinku Jain, Angeliki Buku, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Journal of molecular biology 2011 topics set
Binary complex crystal structure of DNA polymerase β reveals multiple conformations of the templating 8-oxoguanine lesion. Vinod K Batra, David D Shock, William A Beard, Charles E McKenna, Samuel H Wilson Proceedings of the National Academy of Sciences of the United States of America 2011 new
The G157C mutation in the Escherichia coli sliding clamp specifically affects initiation of replication. Line Johnsen, Ingvild Flåtten, Morigen, Bjørn Dalhus, Magnar Bjørås, Torsten Waldminghaus, Kirsten Skarstad Molecular microbiology 2011 new
A triad interaction in the fingers subdomain of DNA polymerase beta controls polymerase activity. Drew L Murphy, Joachim Jaeger, Joann B Sweasy Journal of the American Chemical Society 2011 topics set
Role of a GAG hinge in the nucleotide-induced conformational change governing nucleotide specificity by T7 DNA polymerase. Zhinan Jin, Kenneth A Johnson The Journal of biological chemistry 2011 topics set
The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism. Eugene Y Wu, Lorena S Beese The Journal of biological chemistry 2011 topics set
Involvement of residues of the 29 terminal protein intermediate and priming domains in the formation of a stable and functional heterodimer with the replicative DNA polymerase. Alicia Del Prado, Laurentino Villar, Miguel de Vega, Margarita Salas Nucleic acids research 2011 new
ATR-mediated phosphorylation of DNA polymerase eta is needed for efficient recovery from UV damage. Thomas Göhler, Simone Sabbioneda, Catherine M Green, Alan R Lehmann J Cell Biol 2011 topics set
Long-range PCR with a DNA polymerase fusion. Holly H Hogrefe, Michael C Borns Methods in molecular biology (Clifton, N.J.) 2011 topics set
Structure of a preternary complex involving a prokaryotic NHEJ DNA polymerase. Nigel C Brissett, Maria Jose Martin, Robert S Pitcher, Julie Bianchi, Raquel Juarez, Andrew J Green, Gavin C Fox, Luis Blanco, Aidan J Doherty Molecular cell 2011 topics set
A257T linker region mutant of T7 helicase-primase protein is defective in DNA loading and rescued by T7 DNA polymerase. Gayatri Patel, Daniel S Johnson, Bo Sun, Manjula Pandey, Xiong Yu, Edward H Egelman, Michelle D Wang, Smita S Patel The Journal of biological chemistry 2011 pols set
Structure and mechanism of human DNA polymerase η Christian Biertümpfel, Yaofeng Zhao, Yuji Kondo, Santiago Ramón-Maiques, Mark T Gregory, Jae Young Lee, Chikahide Masutani, Alan R Lehmann, Fumio Hanaoka, Wei Wen Yang Nature 2011 topics set
A Crystallographic Study of the Role of Sequence Context in Thymine Glycol Bypass by a Replicative DNA Polymerase Serendipitously Sheds Light on the Exonuclease Complex. Pierre Aller, Stéphanie Duclos, Susan S Wallace, Sylvie Doublié Journal of molecular biology 2011 new
One-year monthly survey of rotavirus, astrovirus and norovirus in three sewage treatment plants (STPs) in Beijing, China and associated health risk assessment. Xiao Q He, Li Cheng, D Y Zhang, Xiang M Xie, D H Wang, Zhengqiang Wang Water science and technology : a journal of the International Association on Water Pollution Research 2011 new
1H, 13C, and 15N NMR assignments of the Pyrococcus abyssi DNA polymerase II intein. Jiajing Liu, Zhenming Du, Clayton D Albracht, Roshni O Naidu, Kenneth V Mills, Chunyu Wang Biomolecular NMR assignments 2011 pols set
The in vitro fidelity of yeast DNA polymerase δ and polymerase ε holoenzymes during dinucleotide microsatellite DNA synthesis. Amy L Abdulovic, Suzanne E Hile, Thomas A Kunkel, Kristin A Eckert DNA repair 2011 topics set
[Effects of DNA polymerase beta on the genotoxicity and genetic instability induced by benzo(a)pyrene]. Mo Yang, Mei Wu, Jie Cui, Chen Chen, Zun-zhen Zhang Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 2011 new
The SMC-like protein complex SbcCD enhances DNA polymerase IV-dependent spontaneous mutation in Escherichia coli. Kimberly A M Storvik, Patricia L Foster J Bacteriol 2011 new
Breaking the rules: bacteria that use several DNA polymerase IIIs. Charles S McHenry EMBO reports 2011 pols set
Bypass of Aflatoxin B(1) Adducts by the Sulfolobus solfataricus DNA Polymerase IV. Surajit Banerjee, Kyle L Brown, Martin Egli, Michael P Stone Journal of the American Chemical Society 2011 topics set
Mismatch repair-independent tandem repeat sequence instability resulting from ribonucleotide incorporation by DNA polymerase ε. Alan B Clark, Scott A Lujan, Grace E Kissling, Thomas A Kunkel DNA repair 2011 topics set
Studies on Human DNA Polymerase {epsilon} and GINS Complex and Their Role in DNA Replication. Vladimir P Bermudez, A Farina, V Raghavan, Inger Tappin, Jerard Hurwitz The Journal of biological chemistry 2011 pols set
Total biosynthesis of diterpene aphidicolin, a specific inhibitor of DNA polymerase α: heterologous expression of four biosynthetic genes in Aspergillus oryzae. Ryuya Fujii, Atsushi Minami, Tae Tsukagoshi, Natsuko Sato, Takehiko Sahara, Satoru Ohgiya, Katsuya Gomi, Hideaki Oikawa Bioscience, biotechnology, and biochemistry 2011 topics set
Crystal structure of DNA polymerase III beta sliding clamp from Mycobacterium tuberculosis. Wen-Jun Gui, Shi-Qiang Lin, Yuan-Yuan Chen, Xian-En Zhang, Li-Jun Bi, Tao Jiang Biochem Biophys Res Commun 2011 topics set
A model for transition of 5'-nuclease domain of DNA polymerase I from inert to active modes. Ping Xie, Jon R Sayers PloS one 2011 complete Jon R Sayers*
Strand annealing and terminal transferase activities of a B-family DNA polymerase. Zhongfeng Zuo, Hsiang-Kai Lin, Michael A Trakselis Biochemistry 2011 complete Michael A Trakselis*
Characterization of DNA polymerase β from Danio rerio by overexpression in E. coli using the in vivo/in vitro compatible pIVEX plasmid. Tomomi Ishido, Naoshi Yamazaki, Mitsuru Ishikawa, Ken Hirano Microbial cell factories 2011 topics set
DNA polymerase β as a novel target for chemotherapeutic intervention of colorectal cancer. Aruna S Jaiswal, Sanjeev Banerjee, Ritu Aneja, Fazlul H Sarkar, David A Ostrov, Satya Narayan PloS one 2011 new
Structural and mutational studies of a hyperthermophilic intein from DNA polymerase II of Pyrococcus abyssi. Zhenming Du, Jiajing Liu, Clayton D Albracht, Alice Hsu, Wen Chen, Michelle D Marieni, Kathryn M Colelli, Jennie E Williams, Julie N Reitter, Kenneth V Mills, Chunyu Wang The Journal of biological chemistry 2011 pols set
Recent advances in DAPYs and related analogues as HIV-1 NNRTIs. Xuwang Chen, Peng Zhan, Dongyue Li, Erik De Clercq, Xinyong Liu Current medicinal chemistry 2011 pols set
Helicase-DNA polymerase interaction is critical to initiate leading-strand DNA synthesis. Huidong Zhang, Seung-Joo Lee, B Zhu, Ngoc Quang Tran, Stanley Tabor, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 2011 topics set
Phosphorylation of the p68 Subunit of Pol δ Acts as a Molecular Switch to Regulate Its Interaction with PCNA. Amal A Rahmeh, Yajing Zhou, Bin Xie, Hao Li, Ernest Y C Lee, Marietta Y W T Lee Biochemistry 2011 new
A novel ubiquitin binding mode in the S. cerevisiae translesion synthesis DNA polymerase η. Yongxing Ai, Jialiang Wang, Robert E Johnson, Lajos Haracska, Louise Prakash, Zhihao Zhuang Molecular bioSystems 2011 partial results
Role of DNA polymerase beta in the genotoxicity of arsenic. Yanhao Lai, Wei Zhao, Chen Chen, Mei Wu, Zhenzhong Zhang Environmental and molecular mutagenesis 2011 topics set
HIV-1 NNRTIs: Structural diversity, pharmacophore similarity, and implications for drug design. Peng Zhan, Xuwang Chen, Dongyue Li, Zengjun Fang, Erik De Clercq, Xinyong Liu Medicinal research reviews 2011 pols set
Synthesis and biological evaluation of novel 5-alkyl-2-arylthio-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. Jing Zhang, Peng Zhan, Jingde Wu, Zhongjie Li, Yan Jiang, Weiying Ge, Christophe Pannecouque, Erik De Clercq, Xinyong Liu Bioorganic & medicinal chemistry 2011 pols set
Escherichia coli processivity clamp β from DNA polymerase III is dynamic in solution. Jing Fang, John R Engen, Penny J Beuning Biochemistry 2011 topics set
Identification of low-molecular weight inhibitors of HIV-1 reverse transcriptase using a cell-based high-throughput screening system. O Jegede, A Khodyakova, M Chernov, J Weber, L Menéndez-Arias, A Gudkov, ME Quiñones-Mateu Antiviral research 2011 pols set
Phosphonoformic acid inhibits viral replication by trapping the closed form of the DNA polymerase. Karl E Zahn, Egor P Tchesnokov, Matthias Götte, Sylvie Doublié The Journal of biological chemistry 2011 pols set
DNA synthesis across an abasic lesion by yeast REV1 DNA polymerase. Deepak T Nair, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Journal of molecular biology 2011 new
The DNA polymerase activity of Saccharomyces cerevisiae Rev1 is biologically significant. Mary Ellen Wiltrout, Graham C Walker Genetics 2011 pols set
Initiation of HIV reverse transcription: is enzyme flipping required? Matthias Götte Viruses 2011 pols set
Impact of primer-induced conformational dynamics of HIV-1 reverse transcriptase on polymerase translocation and inhibition. Anick Auger, Greg L Beilhartz, Siqi Zhu, Elizabeth Cauchon, Jean-Pierre Falgueyret, Jay A Grobler, Maryam Ehteshami, Matthias Götte, Roman A Melnyk The Journal of biological chemistry 2011 pols set
Inhibition of multi-drug resistant HIV-1 reverse transcriptase by nucleoside β-triphosphates. Chandravanu Dash, Yousef Ahmadibeni, Michael J Hanley, Jui Pandhare, Mathias Gotte, Stuart F J Le Grice, Keykavous Parang Bioorganic & medicinal chemistry letters 2011 pols set
Effects of mutations F61A and A62V in the fingers subdomain of HIV-1 reverse transcriptase on the translocational equilibrium. Brian J Scarth, Suzanne McCormick, Matthias Götte Journal of molecular biology 2011 pols set
Dynamic coupling between the motors of DNA replication: hexameric helicase, DNA polymerase, and primase. Smita S Patel, Manjula Pandey, Divya Nandakumar Current opinion in chemical biology 2011 new
K70Q adds high-level tenofovir resistance to "Q151M complex" HIV reverse transcriptase through the enhanced discrimination mechanism. Atsuko Hachiya, Eiichi N Kodama, Matthew M Schuckmann, Karen A Kirby, Eleftherios Michailidis, Yasuko Sakagami, Shinichi Oka, Kamalendra Singh, Stefan G Sarafianos PloS one 2011 pols set
Novel structure of an N-terminal domain that is crucial for the dimeric assembly and DNA-binding of an archaeal DNA polymerase D large subunit from Pyrococcus horikoshii. Ikuo Matsui, Yuji Urushibata, Yulong Shen, Eriko Matsui, Hideshi Yokoyama FEBS letters 2011 topics set
In silico study of the inhibition of DNA polymerase by a novel catalpol derivative. Osvaldo A Martin, Hugo A Garro, Marcela B Kurina Sanz, Carlos Rodolfo Pungitore, Carlos E Tonn Journal of molecular modeling 2011 topics set
Ubiquitylation of DNA polymerase λ. Enni Markkanen, Barbara van Loon, Elena Ferrari, Ulrich Hübscher FEBS letters 2011 new
The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an ajar intermediate conformation in the nucleotide selection mechanism E Wu, L Beese The Journal of biological chemistry 2011 topics set
Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates. Dimitri Topalis, Ugo Pradère, Vincent Roy, Christophe Caillat, Ahmed Azzouzi, Julie Broggi, Robert Snoeck, Graciela Andrei, Jay Lin, Staffan Eriksson, Julie A C Alexandre, Chahrazade El-Amri, Dominique Deville-Bonne, Philippe Meyer, Jan Balzarini, Luigi A Agrofoglio Journal of medicinal chemistry 2011 new
Selective inhibition of Human Immunodeficiency Virus type 1 (HIV-1) by a novel family of tricyclic nucleosides. María-Cruz Bonache, Alessandra Cordeiro, Ernesto Quesada, Els Vanstreels, Dirk Daelemans, María-José Camarasa, Jan Balzarini, Ana San-Félix Antiviral research 2011 pols set
Enzymatic assembly of overlapping DNA fragments. Daniel G Gibson Methods in enzymology 2011 topics set
Sites and roles of phosphorylation of the human cytomegalovirus DNA polymerase subunit UL44. Laurie A Silva, Blair L Strang, Eric W Lin, Jeremy P Kamil, Donald M Coen Virology 2011 pols set
Distinct roles of the active-site Mg2+ ligands, Asp882 and Asp705, of DNA polymerase I (Klenow fragment) during the prechemistry conformational transitions. Oya Bermek, Nigel D F Grindley, Catherine M Joyce The Journal of biological chemistry 2011 topics set
White spot syndrome virus Orf514 encodes a bona fide DNA polymerase. Enrique de-la-Re-Vega, Karina D Garcia-Orozco, Aldo A Arvizu-Flores, Gloria Yepiz-Plascencia, Adriana Muhlia-Almazan, Jesús Hernández, Luis G Brieba, Rogerio R Sotelo-Mundo Molecules (Basel, Switzerland) 2011 topics set
Rapid and sensitive detection of DNA polymerase fidelity by singly labeled smart fluorescent probes. Chen Song, Chen Zhang, Meiping Zhao Biosens Bioelectron 2011 topics set
Roles of DNA polymerase I in leading and lagging-strand replication defined by a high-resolution mutation footprint of ColE1 plasmid replication. JM Allen, DM Simcha, NG Ericson, DL Alexander, JT Marquette, BP Van Biber, CJ Troll, R Karchin, JH Bielas, Lawrence A Loeb, Manel Camps Nucleic acids research 2011 topics set
DNA polymerase eta and chemotherapeutic agents. Kai-Ming Chou Antioxidants & redox signaling 2011 pols set
Protected immobilization of Taq DNA polymerase by active site masking on self-assembled monolayers of ω-functionalized thiols. Gumjung Lim, Hyun Jin Hwang, Jeong Hee Kim Analytical biochemistry 2011 pols set
Pre-steady-state kinetic analysis of the incorporation of anti-HIV nucleotide analogs catalyzed by human X- and Y-family DNA polymerases. Jessica A Brown, Lindsey R Pack, Jason D Fowler, Zucai Suo Antimicrobial agents and chemotherapy 2011 new
Liver-specific gene therapy of hepatocellular carcinoma by targeting human telomerase reverse transcriptase with pegylated immuno-lipopolyplexes. Yurong Hu, Yingying Shen, Baofang Ji, Shasha Yin, Xueling Ren, Tingting Chen, Yue Ma, Zhenzhong Zhang, Yongqing Zhang European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2011 new
Combinational RNAi gene therapy of hepatocellular carcinoma by targeting human EGFR and TERT. Yurong Hu, Yingying Shen, Baofang Ji, Lei Wang, Zhenzhong Zhang, Yongqing Zhang European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2011 new
Analysis of differential gene expression by bead-based fiber-optic array in nonfunctioning pituitary adenomas. Zhiquan Jiang, Songbo Gui, Yongqing Zhang Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2011 new
Recombinant adenovirus-mediated human telomerase reverse transcriptase gene can stimulate cell proliferation and maintain primitive characteristics in bovine mammary gland epithelial cells. Xiao-Ying He, Yue-Mao Zheng, Jie Lan, Yue-Hong Wu, Jing Yan, Xiao-Ning He, Tuo Zhang, Yu-Long He, Yan-Ling Zheng, Yongqing Zhang Development, growth & differentiation 2011 new
Fragment Screening and HIV Therapeutics. Joseph David Bauman, Disha Patel, Edward Arnold Topics in current chemistry 2011 pols set
A new proofreading mechanism for lesion bypass by DNA polymerase-λ Emmanuele Crespan, Giovanni Maga, Ulrich Hübscher EMBO reports 2011 topics set
Evaluation of the role of the vaccinia virus uracil DNA glycosylase and A20 proteins as intrinsic components of the DNA polymerase holoenzyme. Kathleen A Boyle, Eleni S Stanitsa, Matthew D Greseth, Jill K Lindgren, Paula Traktman The Journal of biological chemistry 2011 pols set
Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China. Tao Dong, Yongqing Zhang, Ke Yi Xu, Huiping Yan, Ian James, Yanchun Peng, Marie-Eve Blais, Silvana Gaudieri, Xinyue Chen, Wenhui Lun, Hao Wu, Wen Yan Qu, Tim Rostron, Ning Li, Yu Mao, Simon Mallal, Xiaoning Xu, Andrew McMichael, Mina John, Sarah L Rowland-Jones Blood 2011 pols set
Mechanism of resistance to GS-9148 conferred by the Q151L mutation in HIV-1 reverse transcriptase. Brian J Scarth, Kirsten L White, James M Chen, Eric B Lansdon, S Swaminathan, Michael D Miller, Matthias Götte Antimicrobial agents and chemotherapy 2011 pols set
Co-expression of herpes simplex virus thymidine kinase and Escherichia coli nitroreductase by an hTERT-driven adenovirus vector in breast cancer cells results in additive anti-tumor effects. Bin Yu, Yongqing Zhang, Yang Zhan, Xiao Zha, Yonege Wu, Xizhen Zhang, Qingzhe Dong, Wei Kong, Xianghui Yu Oncology reports 2011 new
Analysis of differential gene expression using fiber-optic bead array and pathway analyses in pituitary adenomas. Zhiquan Jiang, Songbo Gui, Yongqing Zhang Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2011 new
Nontemplate polymerization of free nucleotides into genetic elements by thermophilic DNA polymerase in vitro. Davis W Cheng, Alejandro Calderón-Urrea Nucleosides, nucleotides & nucleic acids 2011 new
Knockdown of hTERT alters biophysical properties of K562 cells resulting in decreased migration rate in vitro. Yongqing Zhang, Xiaopeng Chen, Xiaofeng Xu, Xianwei Wang, Xifu Wang, Guihong Yuan, Dagong Sun, Weibo Ka, Dongqi He, Zongyao Wen, Weijuan Yao Cell biochemistry and biophysics 2011 new
Clustering of Alpers disease mutations and catalytic defects in biochemical variants reveal new features of molecular mechanism of the human mitochondrial replicase, Pol {gamma} Liliya Euro, Gregory A Farnum, Eino J H Palin, Anu Suomalainen, Laurie S Kaguni Nucleic acids research 2011 pols set
Detection of lamivudine- or adefovir-resistant hepatitis B virus mutations by a liquid array. Hongyan Liu, Richeng Mao, Lili Fan, Jiahui Xia, Yiliang Li, Yongxi Yin, Xincang Li, Xu Zhao, Hongying Guo, Haoxiang Zhu, Yongqing Zhang, Yaoyue Kang, Jiming Zhang Journal of virological methods 2011 new
Effect of plasmid-mediated RNA interference targeting telomerase reverse transcriptase on lung cancer cells. Linhu Ge, Zhansheng Deng, Yongqing Zhang, Wenlong Shao, Yuan Qiu, Dong Cui, Donghai Huang Oncology reports 2011 new
Micro-RNA quantification using DNA polymerase and pyrophosphate quantification. Hsiang-Ping Yu, Yi-Ling Hsiao, Hung-Yin Pan, Chih-Hung Huang, Shao-Yi Hou Analytical biochemistry 2011 new
Diarylpyrimidine-dihydrobenzyloxopyrimidine hybrids: new, wide-spectrum anti-HIV-1 agents active at (sub)-nanomolar level. Dante Rotili, Domenico Tarantino, Marino Artico, Maxim B Nawrozkij, Emmanuel Gonzalez-Ortega, B Clotet, Alberta Samuele, José A Esté, Giovanni Maga, Antonello Mai Journal of medicinal chemistry 2011 pols set
Interaction of HIV-1 reverse transcriptase ribonuclease H with an acylhydrazone inhibitor. Qingguo Gong, Lakshmi Menon, Tatiana Ilina, Lena G Miller, Jinwoo Ahn, Michael A. Parniak, Rieko Ishima Chemical biology & drug design 2011 pols set
Family B DNA polymerase from a hyperthermophilic archaeon Pyrobaculum calidifontis: cloning, characterization and PCR application. Syed Farhat Ali, Naeem Rashid, Tadayuki Imanaka, Muhammad Akhtar Journal of bioscience and bioengineering 2011 new
RNAi targeting of hTERT gene expression induces apoptosis and inhibits the proliferation of lung cancer cells. Linhu Ge, Wenlong Shao, Yongqing Zhang, Yuan Qiu, Dong Cui, Donghai Huang, Zhansheng Deng Oncology letters 2011 new
Characterization of the E138K resistance mutation in HIV-1 reverse transcriptase conferring susceptibility to etravirine in B and non-B HIV-1 subtypes. Eugene L Asahchop, Maureen Oliveira, Mark A. Wainberg, Bluma G Brenner, Daniela D Moisi, Thomas D'Aquin Toni, Cecile L Tremblay Antimicrobial agents and chemotherapy 2011 pols set
Compensation by the E138K mutation in HIV-1 reverse transcriptase for deficits in viral replication capacity and enzyme processivity associated with the M184I/V mutations. Hong-Tao Xu, Eugene L Asahchop, Maureen Oliveira, Peter K Quashie, Yudong Quan, Bluma G Brenner, Mark A. Wainberg Journal of virology 2011 pols set
Subtype diversity associated with the development of HIV-1 resistance to integrase inhibitors. Bluma G Brenner, Matthew Lowe, Daniela D Moisi, Isabelle Hardy, Simon Gagnon, Hugues Charest, Jean Guy Baril, Mark A. Wainberg, Michel Roger Journal of medical virology 2011 pols set
Cloning and sequence analysis of novel DNA polymerases from thermophilic Geobacillus species isolated from hot springs in Turkey: characterization of a DNA polymerase I from Geobacillus kaue strain NB. Melike Çağlayan, Neş'e Bilgin Applied biochemistry and biotechnology 2011 new
Transmission dynamics of the M184V drug resistance mutation in primary HIV infection. Mark A. Wainberg, Daniela D Moisi, Maureen Oliveira, Thomas D'Aquin Toni, Bluma G Brenner The Journal of antimicrobial chemotherapy 2011 pols set
Novel role of base excision repair (BER) in mediating cisplatin cytotoxicity. Anbarasi Kothandapani, Venkata Srinivas Mohan Nimai Dangeti, Ashley R Brown, Lauren A Banze, Xiao-Hong Wang, Robert W Sobol, Steve M Patrick The Journal of biological chemistry 2011 topics set
A 40-year journey in search of selective antiviral chemotherapy. Erik De Clercq Annual review of pharmacology and toxicology 2011 pols set
Synthesis and biological evaluation of 6-substituted 5-alkyl-2-(phenylaminocarbonylmethylthio)pyrimidin-4(3H)-ones as potent HIV-1 NNRTIs. Mingyan Yu, Zhongjie Li, Shuai Liu, Erkang Fan, Christophe Pannecouque, Erik De Clercq, Xinyong Liu ChemMedChem 2011 pols set
In Vitro Gap-directed Translesion DNA Synthesis of an Abasic Site Involving Human DNA Polymerases {epsilon}, {lambda}, and {beta}. Giuseppe Villani, Ulrich Hubscher, Nadege Gironis, Sinikka Parkkinen, Helmut Pospiech, Igor V Shevelev, Giulia di Cicco, Enni Markkanen, Juhani E Syväoja, Nicolas Tanguy Le Gac The Journal of biological chemistry 2011 new
Topical tenofovir, a microbicide effective against HIV, inhibits herpes simplex virus-2 replication. Graciela Andrei, Andrea Lisco, Christophe Vanpouille, Andrea Introini, Emanuela Balestra, Joost van den Oord, Tomas Cihlar, CF Perno, Robert Snoeck, Leonid Margolis, Jan Balzarini Cell host & microbe 2011 pols set
Hepatitis B Virus genotypic differences map structurally close to NRTI resistance hot spots. Eleftherios Michailidis, Kamlendra Singh, Karen A Kirby, Atsuko Hachiya, Wangdon Yoo, Sun Pyo Hong, Soo-Ok Kim, William R Folk, Stefan G Sarafianos International journal of current chemistry 2011 topics set
The high fidelity and unique error signature of human DNA polymerase epsilon. Dagmara A Korona, Kimberly G Lecompte, Zachary F Pursell Nucleic acids research 2011 topics set
Crystal structure of SUMO-modified proliferating cell nuclear antigen. Bret D Freudenthal, John E Brogie, Lokesh Gakhar, Christine M Kondratick, M Todd Washington Journal of molecular biology 2011 new
Whole-genome amplification using Φ29 DNA polymerase. Noël P Burtt Cold Spring Harbor protocols 2011 pols set
Cytomegalovirus ileitis in a patient after liver transplantation-differentiating from de novo IBD. Udayakumar Navaneethan, Preethi G K Venkatesh, Jiang Wang Journal of Crohn's & colitis 2011 new
Mitochondrial DNA polymerase editing mutation, PolgD257A, reduces the diabetic phenotype of Akita male mice by suppressing appetite. R Fox, HS Kim, RL Reddick, Greg C Kujoth, Tomas A Prolla, S Tsutsumi, Y Wada, O Smithies, Naoki Maeda Proceedings of the National Academy of Sciences of the United States of America 2011 pols set
Phenylalanine 171 is a molecular brake for translesion synthesis across benzo[a]pyrene-guanine adducts by human DNA polymerase kappa. Akira Sassa, Naoko Niimi, Hirofumi Fujimoto, Atsushi Katafuchi, Petr Grúz, Manabu Yasui, Ramesh C Gupta, Francis Johnson, Toshihiro Ohta, Takehiko Nohmi Mutation research 2011 topics set
Role of induced fit in limiting discrimination against AZT by HIV reverse transcriptase. Matthew W Kellinger, Kenneth A Johnson Biochemistry 2011 pols set
1-[2-(2-Benzoyl- and 2-benzylphenoxy)ethyl]uracils as potent anti-HIV-1 agents. Mikhail S Novikov, Olga N Ivanova, Alexander V Ivanov, Alexander A Ozerov, Vladimir T Valuev-Elliston, Kartik Temburnikar, Galina V Gurskaya, Sergey N Kochetkov, Christophe Pannecouque, Jan Balzarini, Katherine L Seley-Radtke Bioorganic & medicinal chemistry 2011 pols set
Synthesis and anti-HIV activity of aryl-2-[(4-cyanophenyl)amino]-4-pyrimidinone hydrazones as potent non-nucleoside reverse transcriptase inhibitors. Xiao-Dong Ma, Shi-Qiong Yang, Shuang-Xi Gu, Qiu-Qin He, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque ChemMedChem 2011 pols set
Induction of arginase II mRNA by nitric oxide using an in vitro model of gyrate atrophy of choroid and retina. Masayuki Ohnaka, Emiko Okuda-Ashitaka, Shiho Kaneko, Akira Ando, Masahide Maeda, Kyoji Furuta, Motoshi Suzuki, Kanji Takahashi, Seiji Ito Investigative ophthalmology & visual science 2011 new
The design, synthesis and biological evaluations of C-6 or C-7 substituted 2-hydroxyisoquinoline-1,3-diones as inhibitors of hepatitis C virus. Yue-Lei Chen, Jing Tang, Matthew J Kesler, Yuk Y Sham, Robert Vince, Robert J Geraghty, Zhengqiang Wang Bioorganic & medicinal chemistry 2011 new
N-3 Hydroxylation of Pyrimidine-2,4-diones Yields Dual Inhibitors of HIV Reverse Transcriptase and Integrase. Jing Tang, Kasthuraiah Maddali, Christine D Dreis, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang ACS medicinal chemistry letters 2011 pols set
P-glycoprotein substrate models using support vector machines based on a comprehensive data set. Zhengqiang Wang, Yuanying Chen, Hu Liang, Andreas Bender, Robert C Glen, Aixia Yan Journal of chemical information and modeling 2011 topics set
Changes in adiponectin expression in acute myocardial infarction rats and the significance of bisoprolol intervention. Song Zhang, Ben He, Steven Goldstein, Junbo Ge, Zhengqiang Wang, George Ruiz Canadian journal of physiology and pharmacology 2011 new
Liquid chromatography-mass spectrometry analysis of DNA polymerase reaction products. Goutam Chowdhury, F Peter Guengerich Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.] 2011 new
Dendrimers-delivered short hairpin RNA targeting hTERT inhibits oral cancer cell growth in vitro and in vivo. Xiqiang Liu, Hongzhang Huang, Jianguang Wang, Cheng Wang, Miao Wang, Bin Zhang, Chaobin Pan Biochemical pharmacology 2011 new
Reversible immortalization of rat pancreatic β cells with a novel immortalizing and tamoxifen-mediated self-recombination tricistronic vector. Hui-Ling Wu, Yu Wang, Peiming Zhang, Shu-Fa Li, Xiuping Chen, Yao-Kai Chen, Jun-Gang Li, Shi-Ming Yang, Yong-Ping Su, Jun-Ping Wang, Bing Chen Journal of biotechnology 2011 new
A novel DNA nuclease is stimulated by association with the GINS complex. Zhongjie Li, Miao Pan, Thomas J Santangelo, Wiebke Chemnitz, Wei Yuan, James L Edwards, Jerard Hurwitz, John N Reeve, Zvi Kelman Nucleic acids research 2011 new
Production of recombinant human DNA polymerase delta in a Bombyx mori bioreactor. Yanjiao Zhou, Huiqing Chen, Xincang Li, Yujue Wang, Keping Chen, Sufang Zhang, Xiao Meng, Ernest Y C Lee, Marietta Y W T Lee PloS one 2011 complete Yajing Zhou*
Molecular insights into DNA polymerase deterrents for ribonucleotide insertion. Nisha A Cavanaugh, William A Beard, Vinod K Batra, Lalith Perera, Lee G Pedersen, Samuel H Wilson The Journal of biological chemistry 2011 new
Construction, modification and evaluation of apolipoprotein A-I promoter-driven shRNA expression vectors against hTERT. Xueling Ren, Yue Ma, Min Xu, Tingting Chen, Zhenzhong Zhang, Yongqing Zhang Plasmid 2011 new
Backbone assignment of the little finger domain of a Y-family DNA polymerase. Dejian Ma, Jason D Fowler, Zucai Suo Biomolecular NMR assignments 2011 pols set
Extending the activities of human nucleus pulposus cells with recombinant adeno-associated virus vector-mediated human telomerase reverse transcriptase gene transfer. Jianhong Wu, Deli Wang, Chao Zhang, Chaofeng Wang, Yongqing Zhang, Hongkui Xin, Qing He, Dike Ruan Tissue engineering. Part A 2011 new
Frequent detection of infectious xenotropic murine leukemia virus (XMLV) in human cultures established from mouse xenografts. Yu-An Zhang, Anirban Maitra, Jer-Tsong Hsieh, Charles M Rudin, Craig D Peacock, Collins Karikari, Rolf A Brekken, Victor Stastny, Boning Gao, Luc Girard, Ignacio Wistuba, Eugene Frenkel, John D Minna, Adi F Gazdar Cancer biology & therapy 2011 new
Influence of chitosan nanofiber scaffold on porcine endogenous retroviral expression and infectivity in pig hepatocytes. Bing Han, Xiao-Lei Shi, Jiang-Qiang Xiao, Yongqing Zhang, Xue-Hui Chu, Jin-Yang Gu, Jia-Jun Tan, Zhong-Ze Gu, Yi-Tao Ding World journal of gastroenterology : WJG 2011 new
[Identification of a novel HLA allele HLA-B*40:96]. Chuan-fu Zhu, Yongqing Zhang, Yun-long Zhuang, Yong-hong Song, Yan Liu, Xiang-min Nie Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 2011 new
Rapid cell division contributes to efficient induction of A/T mutations during Ig gene hypermutation. Chie Kano, Rika Ouchida, Tetsuro Kokubo, Ji-Yang Wang Molecular immunology 2011 new
Mitochondrial disorders of DNA polymerase γ dysfunction: from anatomic to molecular pathology diagnosis. Linsheng Zhang, Sherine S L Chan, Daynna J Wolff Archives of pathology & laboratory medicine 2011 new
Photosensitized [2 + 2] cycloaddition of N-acetylated cytosine affords stereoselective formation of cyclobutane pyrimidine dimer. Junpei Yamamoto, Kosuke Nishiguchi, Koichiro Manabe, Chikahide Masutani, Fumio Hanaoka, Shigenori Iwai Nucleic acids research 2011 new
DNA replication and repair bypass machines. Ulrich Hübscher, Giovanni Maga Current opinion in chemical biology 2011 new
P50, the Small Subunit of DNA Polymerase Delta, Is Required for Mediation of the Interaction of Polymerase Delta Subassemblies with PCNA. Yujue Wang, Qian Zhang, Huiqing Chen, Xincang Li, Weijun Mai, Keping Chen, Sufang Zhang, Ernest Y C Lee, Marietta Y W T Lee, Yajing Zhou PloS one 2011 topics set
Unlocking the sugar "steric gate" of DNA polymerases. Jessica A Brown, Zucai Suo Biochemistry 2011 new
Terminal protein-primed amplification of heterologous DNA with a minimal replication system based on phage {Phi}29. Mario Mencía, Pablo Gella, Ana Camacho, Miguel de Vega, Margarita Salas Proceedings of the National Academy of Sciences of the United States of America 2011 topics set
6-Benzoyl-3-hydroxypyrimidine-2,4-diones as dual inhibitors of HIV reverse transcriptase and integrase. Jing Tang, Kasthuraiah Maddali, Christine D Dreis, Yuk Y Sham, Robert Vince, Yves Pommier, Zhengqiang Wang Bioorganic & medicinal chemistry letters 2011 pols set
Generation of a Mono-ubiquitinated PCNA Mimic by Click Chemistry. Silvia Eger, Benoît Castrec, Ulrich Hübscher, Martin Scheffner, Marina Rubini, Andreas Marx Chembiochem : a European journal of chemical biology 2011 new
The human immunodeficiency virus-1 genotype diversity and drug resistance mutations profile of volunteer blood donors from Chinese blood centers. Peibin Zeng, Jingxing Wang, Yi Huang, Xiaoming Guo, Jinming Li, Guoxin Wen, Tonghan Yang, Zhongqiao Yun, Miao He, Yu Liu, Yuzhe Yuan, Jane Schulmann, Simone Glynn, Paul Ness, J Brooks Jackson, Hua Shan Transfusion 2011 pols set
Pyrovanadolysis, a Pyrophosphorolysis-like Reaction Mediated by Pyrovanadate, Mn2+, and DNA Polymerase of Bacteriophage T7. Barak Akabayov, Arkadiusz W Kulczyk, Sabine R Akabayov, Christopher Theile, Larry W McLaughlin, Benjamin Beauchamp, Antoine M van Oijen, Charles C Richardson The Journal of biological chemistry 2011 new
Interactions of the DNA polymerase X from African Swine Fever Virus with the ssDNA. Properties of the total DNA-binding site and the strong DNA-binding subsite. Maria J Jezewska, Michal R Szymanski, Wlodzimierz Bujalowski Biophysical chemistry 2011 new
The N-terminal region of the bacterial DNA polymerase PolC features a pair of domains, both distantly related to domain V of the DNA polymerase III τ subunit. Kęstutis Timinskas The FEBS journal 2011 new
Unexpected role for Helicobacter pylori DNA polymerase I as a source of genetic variability. María-Victoria García-Ortíz, Stéphanie Marsin, Mercedes E Arana, Didier Gasparutto, Raphaël Guérois, Thomas A Kunkel, J Pablo Radicella PLoS genetics 2011 complete J Pablo Radicella*
7-Alkyl-N(2)-substituted-3-deazaguanines. Synthesis, DNA polymerase III inhibition and antibacterial activity. Wei-Chu Xu, George E Wright, Neal C Brown, Zheng-Yu Long, Cheng-Xin Zhi, Sofya Dvoskin, Joseph J Gambino, Marjorie H Barnes, Michelle M Butler Bioorganic & medicinal chemistry letters 2011 complete George E Wright*
Insights into Base Selectivity from the 1.8 A Resolution Structure of an RB69 DNA Polymerase Ternary Complex. Michael Wang, Shuangluo Xia, Gregor Blaha, Thomas A Steitz, William H Konigsberg, Jianhong Wang Biochemistry 2011 topics set
A template-dependent dislocation mechanism potentiates K65R reverse transcriptase mutation development in subtype C variants of HIV-1. Dimitrios Coutsinos, Cédric F Invernizzi, Daniela D Moisi, Maureen Oliveira, Jorge L Martinez-Cajas, Bluma G Brenner, Mark A. Wainberg PloS one 2011 pols set
Cloning, expression, purification, crystallization and preliminary crystallographic analysis of MsDpo4: a Y-family DNA polymerase from Mycobacterium smegmatis. Amit Sharma, Deepak T Nair Acta crystallographica. Section F, Structural biology and crystallization communications 2011 topics set
Substrate mimicry: HIV-1 reverse transcriptase recognizes 6-modified-3'-azido-2',3'-dideoxyguanosine-5'-triphosphates as adenosine analogs. Brian D Herman, Raymond F Schinazi, Hong-Wang Zhang, James H Nettles, Richard Stanton, Mervi Detorio, Aleksandr Obikhod, Ugo Pradère, Steven J Coats, John W Mellors, Nicolas Sluis-Cremer Nucleic acids research 2011 topics set
Sequence Quality Analysis Tool (SQUAT) for HIV-1 Protease and Reverse Transcriptase. Allison K Delong, Mingham Wu, Diane Bennett, Neil Parkin, Zhijin Wu, Joseph W Hogan, Rami Kantor AIDS research and human retroviruses 2011 pols set
Characterization of the χψ subcomplex of Pseudomonas aeruginosa DNA polymerase III. Sirine El Houry Mignan, Gregor Witte, Natalie Naue, Ute Curth BMC molecular biology 2011 topics set
Architecture of the DNA polymerase B-proliferating cell nuclear antigen (PCNA)-DNA ternary complex. Kouta Mayanagi, Shinichi Kiyonari, Hirokazu Nishida, Mihoko Saito, Daisuke Kohda, Yoshizumi Ishino, Tsuyoshi Shirai, Kosuke Morikawa Proceedings of the National Academy of Sciences of the United States of America 2011 new
[Effects of cerebellar fastigial nucleus electrical stimulation on telomerase reverse transcriptase expression and mitochondrial apoptotic pathway in rats with focal cerebral ischemia and reperfusion]. Yi Yang, Jing-Li Liu, Chao Qin, Jin-Pin Li, Xiao-Ling Wang, Zhao-Xia Zhang, Linqi Zhang Zhonghua yi xue za zhi 2011 topics set
Long patch base excision repair compensates for DNA polymerase β inactivation by the C4'-oxidized abasic site. Aaron C Jacobs, Cortney R Kreller, Marc M Greenberg Biochemistry 2011 topics set
Human telomerase reverse transcriptase regulates cyclin D1 and G1/S phase transition in laryngeal squamous carcinoma. Jinming Li, Xinsheng Huang, Xiaofeng Xie, Jianzhong Wang, Maoli Duan Acta oto-laryngologica 2011 new
Role of high-fidelity Escherichia coli DNA polymerase I in replication bypass of a deoxyadenosine DNA-peptide cross-link. Kinrin Yamanaka, Irina G Minko, Steven E Finkel, Myron F Goodman, R Stephen Lloyd Journal of bacteriology 2011 new
Effect of the Y955C mutation on mitochondrial DNA polymerase nucleotide incorporation efficiency and fidelity. Patricia A Estep, Kenneth A Johnson Biochemistry 2011 new
Biochemical analysis of the G517V POLG variant reveals wild-type like activity. Rajesh Kasiviswanathan, William C Copeland Mitochondrion 2011 new
Ribonucleotide discrimination and reverse transcription by the human mitochondrial DNA polymerase. Rajesh Kasiviswanathan, William C Copeland The Journal of biological chemistry 2011 new
Inhibitory effect of novel 5-O-acyl juglones on mammalian DNA polymerase activity, cancer cell growth and inflammatory response. Sayako Maruo, Isoko Kuriyama, Kouji Kuramochi, Kazunori Tsubaki, Hiromi Yoshida, Yoshiyuki Mizushina Bioorganic & medicinal chemistry 2011 new
Inhibitory effects of vitamin K3 derivatives on DNA polymerase and inflammatory activity. Aoganghua Aoganghua, Shin Nishiumi, Kazuki Kobayashi, Masayuki Nishida, Kouji Kuramochi, Kazunori Tsubaki, Midori Hirai, Shinwa Tanaka, Takeshi Azuma, Hiromi Yoshida, Yoshiyuki Mizushina, Masaru Yoshida International journal of molecular medicine 2011 new
Kinetic Mechanism of Active Site Assembly and Chemical Catalysis of DNA Polymerase β PB Balbo, EC Wang, MD Tsai Biochemistry 2011 topics set
Biochemical, inhibition and inhibitor resistance studies of xenotropic murine leukemia virus-related virus reverse transcriptase. Tanyaradzwa P Ndongwe, Adeyemi O Adedeji, Eleftherios Michailidis, Yee Tsuey Ong, Atsuko Hachiya, Bruno Marchand, Emily M Ryan, Devendra K Rai, Karen A Kirby, Angela S Whatley, Donald H Burke, Marc Johnson, Shilei Ding, Yi-Min Zheng, Shan-Lu Liu, Ei-Ichi Kodama, Krista A Delviks-Frankenberry, Vinay K Pathak, Hiroyuki Mitsuya, Michael A. Parniak, Kamalendra Singh, Stefan G Sarafianos Nucleic acids research 2011 pols set
Kinetic analysis of the unique error signature of human DNA polymerase ν Mercedes E Arana, Olga Potapova, Thomas A Kunkel, Catherine M Joyce Biochemistry 2011 topics set
Effects of Intermediates between Vitamins K(2) and K(3) on Mammalian DNA Polymerase Inhibition and Anti-Inflammatory Activity. Yoshiyuki Mizushina, Jun Maeda, Yasuhiro Irino, Masayuki Nishida, Shin Nishiumi, Yasuyuki Kondo, Kazuyuki Nishio, Kouji Kuramochi, Kazunori Tsubaki, Isoko Kuriyama, Takeshi Azuma, Hiromi Yoshida, Masaru Yoshida International journal of molecular sciences 2011 pols set
[Exploration of relationship between the expression level of DNA polymerase beta and 60Co gamma-ray radiosensitivity]. Jie Cui, Xin Xu, Mo Yang, Chen Chen, Wei Zhao, Mei Wu, Zun-zhen Zhang Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 2011 new
[Effect of DNA polymerase beta on apoptosis and mitochondrial membrane potential induced by hydroquinone, a metabolite of benzene]. Chen Chen, Mo Yang, Zun-zhen Zhang, Mei Wu, Wen-wen Deng Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 2011 pols set
Cloning, expression, and PCR application of DNA polymerase from the hyperthermophilic archaeon, Thermococcus celer. Kee Pum Kim, Heejin Bae, In Hye Kim, Suk-Tae Kwon Biotechnol Lett 2011 topics set
Ddc1 checkpoint protein and DNA polymerase ɛ interact with nick-containing DNA repair intermediate in cell free extracts of Saccharomyces cerevisiae. Maria V Sukhanova, Claudine D'Herin, Patricia Auffret van der Kemp, Vladimir V Koval, Serge Boiteux, Olga I Lavrik DNA repair 2011 new
AP-site cleavage activity of tyrosyl-DNA phosphodiesterase 1. Natalia A Lebedeva, Nadejda I Rechkunova, Olga I Lavrik FEBS letters 2011 new
Review of QSAR for DNA polymerase inhibitors and new models for heterogeneous series of compounds. Isela García, Yagamare Fall, Generosa Gómez Current computer-aided drug design 2011 new
Human DNA polymerase beta mutations allowing efficient abasic site bypass. Sonja Gieseking, Konrad Bergen, Francesca Di Pasquale, Kay Diederichs, Wolfram Welte, Andreas Marx The Journal of biological chemistry 2011 topics set
1,N2-Etheno-2'-deoxyguanosine adopts the syn conformation about the glycosyl bond when mismatched with deoxyadenosine. Ganesh Shanmugam, Ivan D Kozekov, F Peter Guengerich, Carmelo J Rizzo, Michael P Stone Chemical research in toxicology 2011 new
Polbase: a repository of biochemical, genetic and structural information about DNA polymerases. BW Langhorst, William E Jack, L Reha-Krantz, NM Nichols Nucleic acids research 2011 complete Brad Langhorst*
PCNA binding domains in all three subunits of yeast DNA polymerase {delta} modulate its function in DNA replication. Narottam Acharya, Roland Klassen, Robert E Johnson, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2011 topics set
Roles of the Four DNA Polymerases of the Crenarchaeon Sulfolobus solfataricus and Accessory Proteins in DNA Replication. Jeong-Yun Choi, Robert Lawton Eoff, Matthew G Pence, Jian Wang, Martha V Martin, Eun-Jin Kim, Lindsay M Folkmann, F Peter Guengerich The Journal of biological chemistry 2011 new
A Triad Interaction in the Fingers Subdomain of DNA Polymerase Beta Controls Polymerase Activity Joann B Sweasy, Joachim Jaeger, Drew L Murphy Journal of the American Chemical Society 2011 topics set
Efficiency and fidelity of human DNA polymerases λ and β during gap-filling DNA synthesis. Jessica A Brown, Lindsey R Pack, Laura E Sanman, Zucai Suo DNA repair 2011 new
Quantitative analysis of the efficiency and mutagenic spectra of abasic lesion bypass catalyzed by human Y-family DNA polymerases. Shanen M Sherrer, Kevin A Fiala, Jason D Fowler, Sean A Newmister, John M Pryor, Zucai Suo Nucleic acids research 2011 new
Characterization of marine X-family DNA polymerases and comparative analysis of base excision repair proteins. Hirofumi Kodera, Ryo Takeuchi, Yukinobu Uchiyama, Yoichi Takakusagi, Kazuki Iwabata, Hidetsugu Miwa, Naoto Hanzawa, Fumio Sugawara, Kengo Sakaguchi Biochemical and biophysical research communications 2011 topics set
Enantioselective binding of second generation pyrrolobenzoxazepinones to the catalytic ternary complex of HIV-1 RT wild-type and L100I and K103N drug resistant mutants. Stefania Butini, Sandra Gemma, Margherita Brindisi, Giuseppe Borrelli, Isabella Fiorini, Alberta Samuele, Aristotele Karytinos, Marcella Facchini, Andrea Lossani, Samantha Zanoli, Giuseppe Campiani, Ettore Novellino, Federico Focher, Giovanni Maga Bioorganic & medicinal chemistry letters 2011 pols set
Structure of the 2-Aminopurine-Cytosine Base Pair Formed in the Polymerase Active Site of the RB69 Y567A-DNA Polymerase. Linda J Reha-Krantz, Chithra Hariharan, Usharani Subuddhi, Shuangluo Xia, Chao Zhao, Jeffrey Beckman, Thomas David Christian, William H Konigsberg Biochemistry 2011 topics set
Indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: new cyclic substituents at indole-2-carboxamide. Giuseppe La Regina, Antonio Coluccia, Andrea Brancale, Francesco Piscitelli, Valerio Gatti, Giovanni Maga, Alberta Samuele, Christophe Pannecouque, Dominique Schols, Jan Balzarini, Ettore Novellino, Romano Silvestri Journal of medicinal chemistry 2011 pols set
[Screening program on novel drug resistance mutations of subtype B' in human immunodeficiency virus type 1 in China.] Han-Ping Li, Wei Guo, Yong-Jian Liu, Zuo-Yi Bao, Lin Li, Dao-Min Zhuang, Si-Yang Liu, Zhengqiang Wang, Xiao-Lin Wang, Jing-Yun Li Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 2011 pols set
Characterization of family IV UDG from Aeropyrum pernix and its application in hot-start PCR by family B DNA polymerase. Xi-Peng Liu, Jian-Hua Liu PloS one 2011 topics set
A simplified method for reconstituting active E. coli DNA polymerase III. Shi-Qiang Lin, Li-Jun Bi, Xian-En Zhang Protein & cell 2011 pols set
A binding free energy decomposition approach for accurate calculations of the fidelity of DNA polymerases. Robert Rucker, Peter Oelschlaeger, Arieh Warshel Proteins 2010 topics set
A cluster of pathogenic mutations in the 3'-5' exonuclease domain of DNA polymerase gamma defines a novel module coupling DNA synthesis and degradation. Karolina Szczepanowska, Françoise Foury Hum Mol Genet 2010 new
Direct polymerase synthesis of reactive aldehyde-functionalized DNA and its conjugation and staining with hydrazines. Veronika Raindlová, Radek Pohl, Miloslav Sanda, Michal Hocek Angewandte Chemie (International ed. in English) 2010 topics set
Metal-ion dependence of the active-site conformation of the translesion DNA polymerase Dpo4 from Sulfolobus solfataricus. Adriana Irimia, Lioudmila V Loukachevitch, Robert Lawton Eoff, F Peter Guengerich, Martin Egli Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 pols set
DNA polymerase eta protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy. Kai-yuan Teng, Miao-zhen Qiu, Zhuang-hua Li, Hui-yan Luo, Zhao-lei Zeng, Rong-zhen Luo, Hui-zhong Zhang, Zhi-qiang Wang, Yu-hong Li, Rui-hua Xu J Transl Med 2010 new
DNA polymerase family X: function, structure, and cellular roles. Jennifer Yamtich, Joann B Sweasy Biochimica et biophysica acta 2010 partial results
Molecular analyses of an unusual translesion DNA polymerase from Methanosarcina acetivorans C2A. Li-Jung Lin, Aya Yoshinaga, Yuyen Lin, Claudia Guzman, Yi-Hsing Chen, Shou Mei, Angelica M Lagunas, Satoshi Koike, Shigenori Iwai, M Ashley Spies, Satish K Nair, Roderick I Mackie, Yoshizumi Ishino, Isaac K O Cann Journal of molecular biology 2010 new
[Ratio of 3' --> 5'-exonuclease and DNA-polymerase activities in normal and cancer cells of rodents and humans]. T P Kravetskaia, N L Ronzhina, V M Krutiakov Tsitologiia 2010 new
Site-directed chemical modification of archaeal Thermococcus litoralis Sh1B DNA polymerase: Acquired ability to read through template-strand uracils. Edita Gaidamaviciute, Daiva Tauraite, Julius Gagilas, Arunas Lagunavicius Biochimica et biophysica acta 2010 pols set
Processing of lagging-strand intermediates in vitro by herpes simplex virus type 1 DNA polymerase. Yali Zhu, Zetang Wu, M Cristina Cardoso, Deborah S Parris J Virol 2010 new
The N348I mutation at the connection subdomain of HIV-1 reverse transcriptase decreases binding to nevirapine. Matthew M Schuckmann, Bruno Marchand, Atsuko Hachiya, Eiichi N Kodama, Karen A Kirby, Kamalendra Singh, Stefan G Sarafianos The Journal of biological chemistry 2010 pols set
Structural basis of ubiquitin recognition by translesion synthesis DNA polymerase iota. Gaofeng Cui, Robert C Benirschke, Han-Fang Tuan, Nenad Juranić, Slobodan Macura, Maria Victoria Botuyan, Georges Mer Biochemistry 2010 new
DNA polymerase structure-based insight on the mutagenic properties of 8-oxoguanine. William A Beard, Vinod K Batra, Samuel H Wilson Mutation research 2010 topics set
Kinetics of mismatch formation opposite lesions by the replicative DNA polymerase from bacteriophage RB69. Matthew Hogg, Jean Rudnicki, John Midkiff, Linda J Reha-Krantz, Sylvie Doublié, Susan S Wallace Biochemistry 2010 topics set
Nucleotide-dependent conformational change governs specificity and analog discrimination by HIV reverse transcriptase. Matthew W Kellinger, Kenneth A Johnson Proceedings of the National Academy of Sciences of the United States of America 2010 partial results
Measurement of kinetic parameters of human platelet DNA polymerase gamma. Jan-Willem Taanman, Margit Heiske, Thierry Letellier Methods 2010 new
Evolution of full-length HBV sequences in chronic hepatitis B patients with sequential lamivudine and adefovir dipivoxil resistance. Chien-Hung Chen, Chuan-Mo Lee, Wei-Chih Tung, Jing-Houng Wang, Chao-Hung Hung, Tsung-Hui Hu, Jyh-Chwan Wang, Sheng-Nan Lu, Chi-Sin Changchien Journal of hepatology 2010 new
Mutator phenotypes due to DNA replication infidelity. Mercedes E Arana, Thomas A Kunkel Seminars in cancer biology 2010 new
Directed evolution of DNA polymerases: construction and screening of DNA polymerase mutant libraries. Christian Gloeckner, Ramon Kranaster, Andreas Marx Current protocols in chemical biology 2010 topics set
A single subunit directs the assembly of the Escherichia coli DNA sliding clamp loader. Ah Young Park, Slobodan Jergic, Argyris Politis, Brandon T Ruotolo, Daniel Hirshberg, Linda L Jessop, Jennifer L Beck, Daniel Barsky, Mike E O'Donnell, Nicholas E Dixon, Carol V Robinson Structure (London, England : 1993) 2010 topics set
Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4. Jimson H Y Wong, Jessica A Brown, Zucai Suo, Paul Blum, Takehiko Nohmi, Hong Ling The EMBO journal 2010 topics set
DNA polymerases beta and lambda mediate overlapping and independent roles in base excision repair in mouse embryonic fibroblasts. Elena K Braithwaite, Padmini S Kedar, Deborah J Stumpo, Barbara Bertocci, Jonathan H Freedman, Leona D Samson, Samuel H Wilson PloS one 2010 new
Parp1 activation in mouse embryonic fibroblasts promotes Pol beta-dependent cellular hypersensitivity to alkylation damage. Elena Jelezcova, Ram N Trivedi, Xiao-Hong Wang, Jiang-bo Tang, Ashley R Brown, Eva M Goellner, S Schamus, JL Fornsaglio, Robert W Sobol Mutation research 2010 complete Robert W Sobol*
HIV-1 RT Inhibitors with a Novel Mechanism of Action: NNRTIs that Compete with the Nucleotide Substrate. Giovanni Maga, Marco Radi, Marie-Aline Gerard, Maurizio Botta, Eric Ennifar Viruses 2010 pols set
Mismatch repair-independent increase in spontaneous mutagenesis in yeast lacking non-essential subunits of DNA polymerase epsilon. Anna Y Aksenova, Kirill Volkov, Jaroslaw Maceluch, Zachary F Pursell, Igor B Rogozin, Thomas A Kunkel, Youri I Pavlov, Erik Johansson PLoS Genet 2010 topics set
Compartmentalized self-replication (CSR) selection of Thermococcus litoralis Sh1B DNA polymerase for diminished uracil binding. Agne Tubeleviciute, Remigijus Skirgaila Protein engineering, design 2010 topics set
Pre-Steady-State Kinetic Analysis of Truncated and Full-Length Saccharomyces cerevisiae DNA Polymerase Eta. Jessica A Brown, Likui Zhang, Shanen M Sherrer, John-Stephen Taylor, Peter M J Burgers, Zucai Suo J Nucleic Acids 2010 partial results
[Effects of DNA polymerase beta on certain genotoxicity of mouse fibroblast cell induced by hydroquinone]. Chen Chen, Yanhao Lai, Mei Wu, Zhenzhong Zhang Wei sheng yan jiu = Journal of hygiene research 2010 pols set
Biochemical techniques for the characterization of G-quadruplex structures: EMSA, DMS footprinting, and DNA polymerase stop assay. Daekyu Sun, Laurence H Hurley Methods in molecular biology (Clifton, N.J.) 2010 new
The eukaryotic replicative DNA polymerases take shape. Erik Johansson, Stuart A Macneill Trends in biochemical sciences 2010 pols set
In search of a selective therapy of viral infections. Erik De Clercq Antiviral research 2010 pols set
The acyclic 2,4-diaminopyrimidine nucleoside phosphonate acts as a purine mimetic in HIV-1 reverse transcriptase DNA polymerization. Brian D Herman, Ivan Votruba, Antonin Holy, Nicolas Sluis-Cremer, Jan Balzarini The Journal of biological chemistry 2010 pols set
Techniques used to study the DNA polymerase reaction pathway. Catherine M Joyce Biochimica et biophysica acta 2010 new
Lead optimization of diarylpyrimidines as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Zhao-Sen Zeng, Yong-Hong Liang, Xiao-Qing Feng, Fen-Er Chen, Christophe Pannecouque, Jan Balzarini, Erik De Clercq ChemMedChem 2010 pols set
Synthesis and anti-HIV activity of 2-naphthyl substituted DAPY analogues as non-nucleoside reverse transcriptase inhibitors. Yong-Hong Liang, Qiu-Qin He, Zhao-Sen Zeng, Zhi-Qian Liu, Xiao-Qing Feng, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq Bioorganic & medicinal chemistry 2010 pols set
Roles of POLD4, smallest subunit of DNA polymerase delta, in nuclear structures and genomic stability of human cells. Qin Miao Huang, Tomohiro Akashi, Yuji Masuda, Kenji Kamiya, Tomonori Takahashi, Motoshi Suzuki Biochem Biophys Res Commun 2010 pols set
A phase I study of telomerase-specific replication competent oncolytic adenovirus (telomelysin) for various solid tumors. John Nemunaitis, Alex W Tong, Michael Nemunaitis, Neil Senzer, Anagha P Phadke, Cynthia Bedell, Ned Adams, Yu-An Zhang, Phillip B Maples, Salina Chen, Beena Pappen, James Burke, Daiju Ichimaru, Yasuo Urata, Toshiyoshi Fujiwara Molecular therapy : the journal of the American Society of Gene Therapy 2010 new
1,2,3-thiadiazole thioacetanilides. Part 2: Synthesis and biological evaluation of a new series of 2-{[4-(3,4-dichlorophenyl)-1,2,3-thiadiazol-5-yl]sulfanyl}acetanilides as HIV-1 inhibitors. Peng Zhan, Xin-Yong Liu, Zhen-Yu Li, Zeng-Jun Fang, Christophe Pannecouque, Erik De Clercq Chemistry & biodiversity 2010 pols set
One-step RNA pathogen detection with reverse transcriptase activity of a mutated thermostable Thermus aquaticus DNA polymerase. Ramon Kranaster, Matthias Drum, Nicole Engel, Manfred Weidmann, Frank T Hufert, Andreas Marx Biotechnology journal 2010 pols set
Higher levels of Zidovudine resistant HIV in the colon compared to blood and other gastrointestinal compartments in HIV infection. Guido van Marle, Deirdre L Church, Kali D Nunweiler, Kris Cannon, Mark A. Wainberg, M John Gill Retrovirology 2010 pols set
Comparative biochemical analysis of recombinant reverse transcriptase enzymes of HIV-1 subtype B and subtype C. Hong-Tao Xu, Yudong Quan, Eugene L Asahchop, Maureen Oliveira, Daniella Moisi, Mark A. Wainberg Retrovirology 2010 pols set
Factors affecting template usage in the development of K65R resistance in subtype C variants of HIV type-1. Dimitrios Coutsinos, Cédric F Invernizzi, Hongtao Xu, Bluma G Brenner, Mark A. Wainberg Antiviral chemistry & chemotherapy 2010 pols set
Antiretroviral drugs. Erik De Clercq Current opinion in pharmacology 2010 pols set
Early nucleoside reverse transcriptase inhibitors for the treatment of HIV: a brief history of stavudine (D4T) and its comparison with other dideoxynucleosides. John C Martin, Michael J M Hitchcock, Erik De Clercq, William H Prusoff Antiviral research 2010 pols set
Differential gene expression by fiber-optic beadarray and pathway in adrenocorticotrophin-secreting pituitary adenomas. Zhi-Quan Jiang, Song-Bo Gui, Ya-Zhuo Zhang Chinese medical journal 2010 new
Expression changes in DNA repair enzymes and mitochondrial DNA damage in aging rat lens. Yongqing Zhang, Lu Zhang, Lan Zhang, Jie Bai, Hongyan Ge, Ping Liu Molecular vision 2010 new
A mutant Pfu DNA polymerase designed for advanced uracil-excision DNA engineering. Morten H H Nørholm BMC Biotechnol 2010 pols set
Stage-dependent inhibition of HIV-1 replication by antiretroviral drugs in cell culture. Daniel A Donahue, Richard D Sloan, Björn D Kuhl, Tamara Bar-Magen, Susan M Schader, Mark A. Wainberg Antimicrobial agents and chemotherapy 2010 pols set
Real-time monitoring of DNA polymerase function and stepwise single-nucleotide DNA strand translocation through a protein nanopore. John Chu, Marcos González-López, Scott L Cockroft, Manuel Amorin, M Reza Ghadiri Angew Chem Int Ed Engl 2010 topics set
Differential impact of the HIV-1 non-nucleoside reverse transcriptase inhibitor mutations K103N and M230L on viral replication and enzyme function. Hong-Tao Xu, Maureen Oliveira, Yudong Quan, Tamara Bar-Magen, Mark A. Wainberg The Journal of antimicrobial chemotherapy 2010 pols set
Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. Matthew J Cuneo, Robert E London Proceedings of the National Academy of Sciences of the United States of America 2010 topics set
The relationship between the molecular structure of natural acetogenins and their inhibitory activities which affect DNA polymerase, DNA topoisomerase and human cancer cell growth. Yuki Matsui, Toshifumi Takeuchi, Yuko Kumamoto-Yonezawa, Masaharu Takemura, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Experimental and therapeutic medicine 2010 new
mip1 containing mutations associated with mitochondrial disease causes mutagenesis and depletion of mtDNA in Saccharomyces cerevisiae. Jeffrey D Stumpf, Christopher M Bailey, Diana Spell, Matthew Stillwagon, Karen S Anderson, William C Copeland Human molecular genetics 2010 topics set
[Effect of DNA polymerase beta on repair of DNA damage induced by benzo(a) pyrene]. Mei Wu, Yanhao Lai, Zhenzhong Zhang Wei sheng yan jiu = Journal of hygiene research 2010 new
Modeling DNA polymerase μ motions: subtle transitions before chemistry. Yingqian Li, Tamar Schlick Biophysical journal 2010 topics set
Exploration of piperidine-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-Phenyl derivatives with broad potency against resistant mutant viruses. Guozhi Tang, Denis J Kertesz, Minmin Yang, Xianfeng Lin, Zhengqiang Wang, Wentao Li, Zongxing Qiu, Junli Chen, Jianghua Mei, Li Chen, Taraneh Mirzadegan, Seth F Harris, Armando G Villaseñor, Jennifer Fretland, William L Fitch, Julie Qi Hang, Gabrielle M Heilek, Klaus Klumpp Bioorganic & medicinal chemistry letters 2010 complete Guozhi Tang*
Synthesis and biological evaluation of 4-(hydroxyimino)arylmethyl diarylpyrimidine analogues as potential non-nucleoside reverse transcriptase inhibitors against HIV. Xiao-Qing Feng, Zhao-Sen Zeng, Yong-Hong Liang, Fen-Er Chen, Christophe Pannecouque, Jan Balzarini, Erik De Clercq Bioorganic & medicinal chemistry 2010 new
Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine. Barbara van Loon, Enni Markkanen, Ulrich Hübscher DNA repair 2010 new
The p12 subunit of human polymerase delta modulates the rate and fidelity of DNA synthesis. Xiao Meng, Yanjiao Zhou, Ernest Y C Lee, Marietta Y W T Lee, David N Frick Biochemistry 2010 pols set
Characterization of a Y-Family DNA Polymerase eta from the Eukaryotic Thermophile Alvinella pompejana. Sayo Kashiwagi, Isao Kuraoka, Yoshie Fujiwara, Kenichi Hitomi, Quen J Cheng, Jill O Fuss, David S Shin, Chikahide Masutani, John A Tainer, Fumio Hanaoka, Shigenori Iwai Journal of nucleic acids 2010 pols set
Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine . Jeff W Beckman, Michael Wang, Gregor Blaha, Jianhong Wang, William H Konigsberg Biochemistry 2010 topics set
Characteristics of hepatic igf-ii expression and monitored levels of circulating igf-ii mRNA in metastasis of hepatocellular carcinoma. Jing Qian, Dengfu Yao, Zhizhen Dong, Wei Wu, Liwei Qiu, Ninghua Yao, Shanshan Li, Yinzhu Bian, Zhengqiang Wang, Gongsheng Shi American journal of clinical pathology 2010 new
Novel 1,3-dihydro-benzimidazol-2-ones and their analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. Anna-Maria Monforte, Patrizia Logoteta, Laura De Luca, Nunzio Iraci, Stefania Ferro, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri Bioorganic & medicinal chemistry 2010 pols set
Inhibitory effect of somatostatin Peptide analogues on DNA polymerase activity and human cancer cell proliferation. Isoko Kuriyama, Anna Miyazaki, Yuko Tsuda, Toshio Yokoi, Yoshio Okada, Toshifumi Takeuchi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Anticancer Res 2010 new
Bioactive triterpenoids from Kadsura heteroclita. Li-Jia Xu, Zong-Gen Peng, Hong-Shan Chen, Jie Wang, Pei-Gen Xiao Chemistry & biodiversity 2010 pols set
Ubc4 and Not4 regulate steady-state levels of DNA polymerase-alpha to promote efficient and accurate DNA replication. Justin Haworth, Robert C Alver, Melissa Anderson, Anja-Katrin Bielinsky Mol Biol Cell 2010 new
Translesion DNA synthesis polymerases in DNA interstrand crosslink repair. TheVinh Ho, OrlandoD Schärer Environmental and molecular mutagenesis 2010 topics set
Ubiquitin-dependent regulation of translesion polymerases. AbelCS Chun, Dong-Yan Jin Biochemical Society transactions 2010 topics set
Effect of oxymatrine on the replication cycle of hepatitis B virus in vitro. Wen-Sheng Xu, Ke-Kai Zhao, Xiao-Hui Miao, Wu Ni, Xiong Cai, Rui-Qi Zhang, Jun-Xue Wang World journal of gastroenterology : WJG 2010 new
POLD2 and KSP37 (FGFBP2) correlate strongly with histology, stage and outcome in ovarian carcinomas. Bente Vilming Elgaaen, Kari Bente Foss Haug, Junbai Wang, Ole Kristoffer Olstad, Dario Fortunati, Mathias Onsrud, Anne Cathrine Staff, Torill Sauer, Kaare M Gautvik PloS one 2010 new
The interaction between DNA polymerase lambda and anticancer nucleoside analogs. Miguel Garcia-Diaz, Michael S Murray, Thomas A Kunkel, Kai-Ming Chou The Journal of biological chemistry 2010 topics set
Electrochemical detection of beta-1,3-glucanase gene from transgenic capsicums using asymmetric PCR generated by a detecting probe and an anchoring probe. Guofan Wu, Zhengqiang Wang, Huini Zhang, Ning Yang, Jie Du, Xiaoqing Lu, Jingwan Kang Journal of biotechnology 2010 new
Ultrasensitive chemiluminescence quantification of single-nucleotide polymorphisms by using monobase-modified Au and CuS nanoparticles. Caifeng Ding, Zhengqiang Wang, Hua Zhong, Shusheng Zhang Biosensors & bioelectronics 2010 new
A 'DNA replication' signature of progression and negative outcome in colorectal cancer. Marie-Jeanne Pillaire, Janick Selves, K Gordien, P-A Gourraud, P-A Gouraud, Catherine Gentil, M Danjoux, C Do, V Negre, Anne Bieth, R Guimbaud, Didier Trouche, Philippe Pasero, M Méchali, Jean-Sébastien Hoffmann, Christophe Cazaux Oncogene 2010 new
Mutational clusters generated by non-processive polymerases: A case study using DNA polymerase betain vitro. Libertad García-Villada, John W Drake DNA repair 2010 new
Kinetic basis of nucleotide selection employed by a protein template-dependent DNA polymerase. Jessica A Brown, Jason D Fowler, Zucai Suo Biochemistry 2010 new
Association of human cytomegalovirus proteins IRS1 and TRS1 with the viral DNA polymerase accessory subunit UL44. Blair L Strang, Adam P Geballe, Donald M Coen The Journal of general virology 2010 new
The C8-2'-deoxyguanosine adduct of 2-amino-3-methylimidazo[1,2-d]naphthalene, a carbocyclic analogue of the potent mutagen 2-amino-3-methylimidazo[4,5-f]quinoline, is a block to replication in vitro. Plamen P Christov, Goutam Chowdhury, Craig A Garmendia, Feng Wang, James S Stover, C Eric Elmquist, Albena Kozekova, Karen C Angel, Robert J Turesky, Michael P Stone, F Peter Guengerich, Carmelo J Rizzo Chemical research in toxicology 2010 pols set
Structure of the 1,N(2)-etheno-2'-deoxyguanosine lesion in the 3'-G(epsilon dG)T-5' sequence opposite a one-base deletion. Ganesh Shanmugam, Ivan D Kozekov, F Peter Guengerich, Carmelo J Rizzo, Michael P Stone Biochemistry 2010 new
Contributions of nucleotide excision repair, DNA polymerase eta, and homologous recombination to replication of UV-irradiated herpes simplex virus type 1. Isabella Muylaert, Per Elias The Journal of biological chemistry 2010 new
UmuD(2) inhibits a non-covalent step during DinB-mediated template slippage on homopolymeric nucleotide runs. James J Foti, Angela M DeLucia, Catherine M Joyce, Graham C Walker The Journal of biological chemistry 2010 new
Inhibitory effects of docosyl p-coumarate on DNA topoisomerase activity and human cancer cell growth. Yoshiyuki Mizushina, Katsumi Nishimura, Yukiko Takenaka, Toshifumi Takeuchi, Fumio Sugawara, Hiromi Yoshida, Takao Tanahashi International journal of oncology 2010 new
Active site mutations in mammalian DNA polymerase delta alter accuracy and replication fork progression. Michael W Schmitt, Ranga N Venkatesan, Marie-Jeanne Pillaire, Jean-Sébastien Hoffmann, Julia M Sidorova, Lawrence A Loeb The Journal of biological chemistry 2010 pols set
β-Sitosteryl (6'-O-linoleoyl)-glucoside of soybean (Glycine max L.) crude extract inhibits Y-family DNA polymerases. Sho Horie, Chiaki Okuda, Takatoshi Yamashita, Kenichi Watanabe, Yoshihiro Sato, Yasuhiro Yamaguchi, Toshifumi Takeuchi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Journal of oleo science 2010 new
Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases. Stephanie A Nick McElhinny, Brian E Watts, Dinesh Kumar, Danielle L Watt, Else-Britt Lundström, Peter M J Burgers, Erik Johansson, Andrei Chabes, Thomas A Kunkel Proceedings of the National Academy of Sciences of the United States of America 2010 partial results
[Inhibition of growth and proliferation of Hep-2 cells by targeting hTERT gene using small interference RNA technology]. Haiying Jia, Tao Zhang, Zhi Tang, Jiqun Wang Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 2010 new
Hepatitis C virus core protein induces malignant transformation of biliary epithelial cells by activating nuclear factor-kappaB pathway. Zhi-Hua Li, Qi-Bin Tang, Jie Wang, Ling Zhou, Wen-Lin Huang, Ran-Yi Liu, Ru-Fu Chen Journal of gastroenterology and hepatology 2010 new
DNA conformational changes at the primer-template junction regulate the fidelity of replication by DNA polymerase. Kausiki Datta, Neil P Johnson, Peter H von Hippel Proceedings of the National Academy of Sciences of the United States of America 2010 new
Modifications to the dNTP triphosphate moiety: from mechanistic probes for DNA polymerases to antiviral and anti-cancer drug design. Charles E McKenna, Boris A Kashemirov, Larryn W Peterson, Myron F Goodman Biochimica et biophysica acta 2010 new
A cancer-associated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in genomic instability. Danielle L Daee, Tony M Mertz, Polina V Shcherbakova Proceedings of the National Academy of Sciences of the United States of America 2010 new
Reconstitution of the B. subtilis replisome with 13 proteins including two distinct replicases. Glenn M Sanders, H Garry Dallmann, Charles S McHenry Molecular cell 2010 new
Conformational transitions in DNA polymerase I revealed by single-molecule FRET. Yusdi Santoso, Catherine M Joyce, Olga Potapova, Ludovic Le Reste, Johannes Hohlbein, Joseph P Torella, Nigel D F Grindley, Achillefs N Kapanidis Proceedings of the National Academy of Sciences of the United States of America 2010 new
Intrinsic apurinic/apyrimidinic (AP) endonuclease activity enables Bacillus subtilis DNA polymerase X to recognize, incise, and further repair abasic sites. Benito Baños, Laurentino Villar, Margarita Salas, Miguel de Vega Proceedings of the National Academy of Sciences of the United States of America 2010 pols set
DNA structure and the Werner protein modulate human DNA polymerase delta-dependent replication dynamics within the common fragile site FRA16D. Sandeep N Shah, Patricia L Opresko, Xiao Meng, Marietta Y W T Lee, Kristin A Eckert Nucleic acids research 2010 pols set
Novel enzymatic function of DNA polymerase nu in translesion DNA synthesis past major groove DNA-peptide and DNA-DNA cross-links. Kinrin Yamanaka, Irina G Minko, Kei-ichi Takata, Alexander Kolbanovskiy, Ivan D Kozekov, Richard D Wood, Carmelo J Rizzo, R Stephen Lloyd Chemical research in toxicology 2010 new
Genome instability due to ribonucleotide incorporation into DNA. Stephanie A Nick McElhinny, Dinesh Kumar, Alan B Clark, Danielle L Watt, Brian E Watts, Else-Britt Lundström, Erik Johansson, Andrei Chabes, Thomas A Kunkel Nature chemical biology 2010 new
Genome-wide model for the normal eukaryotic DNA replication fork. Andres A Larrea, Scott A Lujan, Stephanie A Nick McElhinny, Piotr A Mieczkowski, Michael A Resnick, Dmitry A Gordenin, Thomas A Kunkel Proceedings of the National Academy of Sciences of the United States of America 2010 new
Residues in the central beta-hairpin of the DNA helicase of bacteriophage T7 are important in DNA unwinding. Ajit K Satapathy, Anna B Kochaniak, Sourav Mukherjee, DJ Crampton, Antoine M van Oijen, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 2010 pols set
Direct role for the RNA polymerase domain of T7 primase in primer delivery. B Zhu, Seung-Joo Lee, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 2010 new
Viral terminal protein directs early organization of phage DNA replication at the bacterial nucleoid. Daniel Muñoz-Espín, Isabel Holguera, David Ballesteros-Plaza, Rut Carballido-López, Margarita Salas Proceedings of the National Academy of Sciences of the United States of America 2010 new
The carboxy-terminal segment of the human cytomegalovirus DNA polymerase accessory subunit UL44 is crucial for viral replication. Laurie A Silva, Arianna Loregian, Gregory S Pari, Blair L Strang, Donald M Coen Journal of virology 2010 pols set
Study on suitability of KOD DNA polymerase for enzymatic production of artificial nucleic acids using base/sugar modified nucleoside triphosphates. Masayasu Kuwahara, Yuuki Takano, Yuuya Kasahara, Hiroki Nara, Hiroaki Ozaki, Hiroaki Sawai, Akio Sugiyama, Satoshi Obika Molecules 2010 new
Analysis of DNA methylation status of the promoter of human telomerase reverse transcriptase in gastric carcinogenesis. Zhengqiang Wang, Jinheng Xu, Xin Geng, Weiming Zhang Archives of medical research 2010 new
Pharmacophore and structure-activity relationships of integrase inhibition within a dual inhibitor scaffold of HIV reverse transcriptase and integrase. Zhengqiang Wang, Jing Tang, Christine E Salomon, Christine D Dreis, Robert Vince Bioorganic & medicinal chemistry 2010 pols set
Yeast telomerase subunit Est1p has guanine quadruplex-promoting activity that is required for telomere elongation. Ming-Liang Zhang, Xia-Jing Tong, Xiao-Hong Fu, Bo O Zhou, Jianyong Wang, Xin-Hua Liao, Qian-Jin Li, Ning Shen, Jianping Ding, Jin-Qiu Zhou Nature structural & molecular biology 2010 new
Leptin upregulates telomerase activity and transcription of human telomerase reverse transcriptase in MCF-7 breast cancer cells. He Ren, Tiansuo Zhao, Xiuchao Wang, Chuntao Gao, Jian Wang, Ming Yu, Jihui Hao Biochemical and biophysical research communications 2010 new
The glycine-rich motif of Pyrococcus abyssi DNA polymerase D is critical for protein stability. Benoît Castrec, Sébastien Laurent, Ghislaine Henneke, Didier Flament, Jean-Paul Raffin Journal of molecular biology 2010 pols set
Selective modulation of DNA polymerase activity by fixed-conformation nucleoside analogues. Robert Lawton Eoff, Colleen E McGrath, Leena Maddukuri, S Giovanna Salamanca-Pinzón, Victor E Marquez, Lawrence J Marnett, F Peter Guengerich, Martin Egli Angewandte Chemie (International ed. in English) 2010 new
Substrate channeling in mammalian base excision repair pathways: passing the baton. Rajendra Prasad, David D Shock, William A Beard, Samuel H Wilson The Journal of biological chemistry 2010 new
Simultaneous disruption of two DNA polymerases, Polη and Polζ, in Avian DT40 cells unmasks the role of Polη in cellular response to various DNA lesions. Kouji Hirota, Eiichiro Sonoda, Takuo Kawamoto, Akira Motegi, Chikahide Masutani, Fumio Hanaoka, Dávid Szüts, Shigenori Iwai, Julian E Sale, Alan R Lehmann, Shunichi Takeda PLoS genetics 2010 complete Shunichi Takeda*
Two modes of interaction of the single-stranded DNA-binding protein of bacteriophage T7 with the DNA polymerase-thioredoxin complex. Sharmistha Ghosh, Samir M Hamdan, Charles C Richardson The Journal of biological chemistry 2010 new
Nucleolin associates with the human cytomegalovirus DNA polymerase accessory subunit UL44 and is necessary for efficient viral replication. Blair L Strang, Steeve Boulant, Donald M Coen Journal of virology 2010 pols set
Cerebral folate deficiency and CNS inflammatory markers in Alpers disease. Oswald Hasselmann, Nenad Blau, Vincent T Ramaekers, Edward V Quadros, J M Sequeira, Markus Weissert Molecular genetics and metabolism 2010 complete Oswald Hasselmann*
Virologic outcomes of first-line HAART and associated factors among Chinese patients with HIV in three sentinel antiretroviral treatment sites. Yuhua Ruan, Hui Xing, Xia Wang, Heng Tang, Zhengqiang Wang, Hongwei Liu, Bin Su, Jianjun Wu, Hanping Li, Lingjie Liao, Jinming Li, Julia Wei Wu, Yiming Shao Tropical medicine & international health : TM & IH 2010 pols set
Small molecule inhibitors of HIV RT Ribonuclease H. Martin Di Grandi, Matthew Olson, Amar S Prashad, Geraldine Bebernitz, Amara Luckay, Stanley Mullen, Yongbo Hu, Girija Krishnamurthy, Keith Pitts, John O'Connell Bioorganic & medicinal chemistry letters 2010 topics set
N1-Heterocyclic pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Michael L Mitchell, Jong Chan Son, Ill Young Lee, Chong-Kyo Lee, Hae Soo Kim, Hongyan Guo, Jianhong Wang, Jaclyn Hayes, Michael Wang, Amber Paul, Eric B Lansdon, James M Chen, Gene Eisenberg, Romas Geleziunas, Lianhong Xu, Choung U Kim Bioorganic & medicinal chemistry letters 2010 partial results
Discovery of piperidin-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-benzyl derivatives with broad potency against resistant mutant viruses. Denis J Kertesz, Christine Brotherton-Pleiss, Minmin Yang, Zhengqiang Wang, Xianfeng Lin, Zongxing Qiu, Donald R Hirschfeld, Shelley K Gleason, Taraneh Mirzadegan, Pete W Dunten, Seth F Harris, Armando G Villaseñor, Julie Qi Hang, Gabrielle M Heilek, Klaus Klumpp Bioorganic & medicinal chemistry letters 2010 partial results
Slow binding-tight binding interaction between benzimidazol-2-one inhibitors and HIV-1 reverse transcriptase containing the lysine 103 to asparagine mutation. Alberta Samuele, Emmanuele Crespan, Samanta Vitellaro, Anna-Maria Monforte, Patrizia Logoteta, Alba Chimirri, Giovanni Maga Antiviral research 2010 pols set
Mechanism of entecavir resistance of hepatitis B virus with viral breakthrough as determined by long-term clinical assessment and molecular docking simulation. Motokazu Mukaide, Yasuhito Tanaka, Tadasu Shin-I, Man-Fung Yuen, Fuat Kurbanov, Osamu Yokosuka, Michio Sata, Yoshiyasu Karino, Gotaro Yamada, Kohsaku Sakaguchi, Etsuro Orito, Manami Inoue, Sumbella Baqai, Ching-Lung Lai, Masashi Mizokami Antimicrobial agents and chemotherapy 2010 new
Loop 1 modulates the fidelity of DNA polymerase {lambda} Katarzyna Bebenek, Miguel Garcia-Diaz, Rui-Zhe Zhou, Lawrence F Povirk, Thomas A Kunkel Nucleic acids research 2010 partial results
The R438W polymorphism of human DNA polymerase lambda triggers cellular sensitivity to camptothecin by compromising the homologous recombination repair pathway. Jean-Pascal Capp, François Boudsocq, Valérie Bergoglio, Didier Trouche, Christophe Cazaux, Luis Blanco, Jean-Sébastien Hoffmann, Yvan Canitrot Carcinogenesis 2010 pols set
Polymerization behavior of Klenow fragment and Taq DNA polymerase in short primer extension reactions. Guojie Zhao, Yifu Guan Acta Biochim Biophys Sin (Shanghai) 2010 topics set
Sensitive and rapid detection of Vibrio corallilyticus by loop-mediated isothermal amplification targeted to the alpha subunit gene of RNA polymerase. G F Liu, Ji-Yang Wang, L W Xu, X Ding, S N Zhou Letters in applied microbiology 2010 new
Rapid detection of peste des petits ruminants virus by a reverse transcription loop-mediated isothermal amplification assay. Lin Li, Jingyue Bao, Xiaoming Wu, Zhengqiang Wang, Junwei Wang, Mingxia Gong, Chunju Liu, Jinming Li Journal of virological methods 2010 pols set
Backbone assignment of the catalytic core of a Y-family DNA polymerase. Dejian Ma, Jason D Fowler, Chunhua Yuan, Zucai Suo Biomol NMR Assign 2010 topics set
DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability. Fanny Lemée, Valérie Bergoglio, Anne Fernandez-Vidal, Alice Machado-Silva, Marie-Jeanne Pillaire, Anne Bieth, Catherine Gentil, Lee Baker, Anne-Laure Martin, Claire Leduc, Elena Lam, Eddy Magdeleine, Thomas Filleron, Naïma Oumouhou, Bernd Kaina, Masayuki Seki, Fanny Grimal, Magali Lacroix-Triki, Alastair Thompson, Henri Roché, Jean-Christophe Bourdon, Richard D Wood, Jean-Sébastien Hoffmann, Christophe Cazaux Proceedings of the National Academy of Sciences of the United States of America 2010 new
Structure-activity analysis of vinylogous urea inhibitors of human immunodeficiency virus-encoded ribonuclease H. Suhman Chung, Michaela Wendeler, Jason W Rausch, Greg L Beilhartz, Matthias Gotte, Barry R O'Keefe, Alun Bermingham, John A Beutler, Shixin Liu, Xiaowei Zhuang, Stuart F J Le Grice Antimicrobial agents and chemotherapy 2010 pols set
Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1. Kodai Hara, Hiroshi Hashimoto, Yoshiki Murakumo, Shunsuke Kobayashi, Toshiaki Kogame, Satoru Unzai, Satoko Akashi, Shunichi Takeda, Toshiyuki Shimizu, Mamoru Sato The Journal of biological chemistry 2010 new
DNA polymerase beta is critical for mouse meiotic synapsis. Dawit Kidane, Alan S Jonason, Timothy S Gorton, Ivailo Mihaylov, Jing Pan, Scott Keeney, Dirk G de Rooij, Terry Ashley, Agnes Keh, Yanfeng Liu, Urmi Banerjee, Daniel Zelterman, Joann B Sweasy The EMBO journal 2010 new
A novel mechanism of sugar selection utilized by a human X-family DNA polymerase. Jessica A Brown, Kevin A Fiala, Jason D Fowler, Shanen M Sherrer, Sean A Newmister, Wade W Duym, Zucai Suo Journal of molecular biology 2010 new
Inhibitory effects of diacylglyceride phospholipids on DNA polymerase and topoisomerase activities, and human cancer cell growth. Chisato Ishimaru, Toshifumi Takeuchi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Medicinal chemistry (Shāriqah (United Arab Emirates)) 2010 new
Rare autosomal dominant POLG1 mutation in a family with metabolic strokes, posterior column spinal degeneration, and multi-endocrine disease. Sarah E Hopkins, Arthur Somoza, Donald L Gilbert Journal of child neurology 2010 pols set
Significance of DNA polymerase delta catalytic subunit p125 induced by mutant p53 in the invasive potential of human hepatocellular carcinoma. Kensaku Sanefuji, Akinobu Taketomi, Tomohiro Iguchi, Keishi Sugimachi, Toru Ikegami, Yo-ichi Yamashita, Tomonobu Gion, Yuji Soejima, Ken Shirabe, Yoshihiko Maehara Oncology 2010 pols set
A novel POLG gene mutation in 4 children with Alpers-like hepatocerebral syndromes. Bulent Kurt, Jaak Jaeken, Johan Van Hove, Lieven Lagae, Ann Löfgren, David B Everman, Parul Jayakar, Ali B Naini, Klaas J Wierenga, Gert Van Goethem, William C Copeland, Salvatore DiMauro Archives of neurology 2010 pols set
Stable interactions between DNA polymerase delta catalytic and structural subunits are essential for efficient DNA repair. Clémentine Brocas, Jean-Baptiste Charbonnier, Claudine Dhérin, Serge Gangloff, Laurent Maloisel DNA repair 2010 new
Functions of base selection step in human DNA polymerase alpha. Shigeru Tanaka, Ke Cao, Atsuko Niimi, Siripan Limsirichaikul, Huang Qin Miao, Noriko Nakamura, Takashi Murate, Yoshinori Hasegawa, Tomonori Takahashi, Motoshi Suzuki DNA repair 2010 topics set
Lack of DNA polymerase mu affects the kinetics of DNA double-strand break repair and impacts on cellular senescence. Romain Chayot, Anne Danckaert, Benjamin Montagne, Miria Ricchetti DNA repair 2010 pols set
Solution structure of the N-terminal domain of the archaeal D-family DNA polymerase small subunit reveals evolutionary relationship to eukaryotic B-family polymerases. Kazuhiko Yamasaki, Yuji Urushibata, Tomoko Yamasaki, Fumio Arisaka, Ikuo Matsui FEBS letters 2010 topics set
Reverse transcriptase in motion: conformational dynamics of enzyme-substrate interactions. Matthias Götte, Jason W Rausch, Bruno Marchand, Stefan G Sarafianos, Stuart F J Le Grice Biochimica et biophysica acta 2010 pols set
DNA polymerases beta and lambda bypass thymine glycol in gapped DNA structures. Ekaterina A Belousova, Giovanni Maga, Yang Fan, Elena A Kubareva, Elena A Romanova, Natalia A Lebedeva, Tatiana S Oretskaya, Olga I Lavrik Biochemistry 2010 new
N348I in HIV-1 reverse transcriptase can counteract the nevirapine-mediated bias toward RNase H cleavage during plus-strand initiation. Mia J Biondi, Greg L Beilhartz, Suzanne McCormick, Matthias Götte The Journal of biological chemistry 2010 pols set
Epidemiological and biological evidence for a compensatory effect of connection domain mutation N348I on M184V in HIV-1 reverse transcriptase. Viktor von Wyl, Maryam Ehteshami, Jori Symons, Philippe Bürgisser, Monique Nijhuis, Lisa M Demeter, Sabine Yerly, Jürg Böni, Thomas Klimkait, Rob Schuurman, Bruno Ledergerber, Matthias Götte, Huldrych F Günthard The Journal of infectious diseases 2010 pols set
Biochemical properties and PCR performance of a family B DNA polymerase from hyperthermophilic Euryarchaeon Thermococcus peptonophilus. Jong Il Lee, Yun Jae Kim, Heejin Bae, Sung Suk Cho, Jung-Hyun Lee, Suk-Tae Kwon Appl Biochem Biotechnol 2010 new
HIV-1 reverse transcriptase connection domain mutations: dynamics of emergence and implications for success of combination antiretroviral therapy. Viktor von Wyl, Maryam Ehteshami, Lisa M Demeter, Philippe Bürgisser, Monique Nijhuis, Jori Symons, Sabine Yerly, Jürg Böni, Thomas Klimkait, Rob Schuurman, Bruno Ledergerber, Matthias Götte, Huldrych F Günthard Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2010 pols set
DNA polymerase beta-dependent long patch base excision repair in living cells. Kenjiro Asagoshi, Yuan Liu, Aya Masaoka, Li Lan, Rajendra Prasad, Julie K Horton, Ashley R Brown, Xiao-Hong Wang, Hussam Moh'd Bdour, Robert W Sobol, John-Stephen Taylor, Akira Yasui, Samuel H Wilson DNA repair 2010 pols set
Refolding active human DNA polymerase nu from inclusion bodies. Mercedes E Arana, Gary K Powell, Lori L Edwards, Thomas A Kunkel, Robert M Petrovich Protein Expr Purif 2010 pols set
DNA polymerase eta, a key protein in translesion synthesis in human cells. Séverine Cruet-Hennequart, Kathleen Gallagher, Anna M Sokòl, Sangamitra Villalan, Aine M Prendergast, Michael P Carty Subcell Biochem 2010 topics set
Phosphorylated Rad 18 directs DNA Polymerase {eta} to sites of stalled replication. Tovah A Day, Komariah Palle, Laura R Barkley, Naoko Kakusho, Ying Zou, Satoshi Tateishi, Alain Verreault, Hisao Masai, Cyrus Vaziri J Cell Biol 2010 pols set
Evolutionary conservation of residues in vertebrate DNA polymerase N conferring low fidelity and bypass activity. Kei-ichi Takata, Mercedes E Arana, Masayuki Seki, Thomas A Kunkel, Richard D Wood Nucleic acids research 2010 complete Richard D Wood*
The molecular chaperone Hsp90 regulates accumulation of DNA polymerase eta at replication stalling sites in UV-irradiated cells. Takayuki Sekimoto, Tsukasa Oda, Franklin Mayca Pozo, Yoshiki Murakumo, Chikahide Masutani, Fumio Hanaoka, Takayuki Yamashita Molecular cell 2010 topics set
Purified canola lutein selectively inhibits specific isoforms of mammalian DNA polymerases and reduces inflammatory response. Sho Horie, Chiaki Okuda, Takatoshi Yamashita, Kenichi Watanabe, Kouji Kuramochi, Masashi Hosokawa, Toshifumi Takeuchi, Makiko Kakuda, Kazuo Miyashita, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Lipids 2010 new
An alternative pathway for Okazaki fragment processing: resolution of fold-back flaps by Pif1 helicase. JasonE Pike, RyanA Henry, PeterMJ Burgers, JudithL Campbell, RobertA Bambara The Journal of biological chemistry 2010 new
Error-free replicative bypass of thymine glycol by the combined action of DNA polymerases kappa and zeta in human cells. Jung-Hoon Yoon, G Bhatia, Satya Prakash, Louise Prakash Proceedings of the National Academy of Sciences of the United States of America 2010 topics set
Human replicative DNA polymerase δ can bypass T-T (6-4) ultraviolet photoproducts on template strands. Takeo Narita, Toshiki Tsurimoto, Junpei Yamamoto, Kana Nishihara, Kaori Ogawa, Eiji Ohashi, Terry Evans, Shigenori Iwai, Shunichi Takeda, Kouji Hirota Genes to cells : devoted to molecular & cellular mechanisms 2010 complete Kouji Hirota*
HIV-1 Ribonuclease H: Structure, Catalytic Mechanism and Inhibitors. Greg L Beilhartz, Matthias Götte Viruses 2010 pols set
Structure and mechanism of human DNA polymerase eta. Christian Biertümpfel, Yaofeng Zhao, Yuji Kondo, Santiago Ramón-Maiques, Mark T Gregory, Jae Young Lee, Chikahide Masutani, Alan R Lehmann, Fumio Hanaoka, Wei Wen Yang Nature 2010 complete Fumio Hanaoka*
EARLY IN SHORT DAYS 7 (ESD7) encodes the catalytic subunit of DNA polymerase epsilon and is required for flowering repression through a mechanism involving epigenetic gene silencing. Iván del Olmo, Leticia López-González, Maria M Martín-Trillo, José M Martínez-Zapater, Manuel Piñeiro, Jose A Jarillo Plant J 2010 complete Jose A Jarillo*
Pushing the limits for amplifying BrdU-labeled DNA encoding 16S rRNA: DNA polymerase as the determining factor. Dad D Roux-Michollet, Joshua P Schimel, Patricia A Holden J Microbiol Methods 2010 complete Dad D Roux-Michollet*
Crystal structures of HIV-1 reverse transcriptase with etravirine (TMC125) and rilpivirine (TMC278): implications for drug design. Eric B Lansdon, Katherine M Brendza, Magdeleine Hung, Ruth Wang, Susmith Mukund, Debi Jin, Gabriel Birkus, Nilima Kutty, Xiaohong Liu J Med Chem 2010 complete Eric B Lansdon*
Processive replication of single DNA molecules in a nanopore catalyzed by phi29 DNA polymerase. Kate R Lieberman, Gerald M Cherf, Michael J Doody, Felix Olasagasti, Yvette Kolodji, Mark Akeson Journal of the American Chemical Society 2010 complete Kate R Lieberman*
Genetic insertions and diversification of the PolB-type DNA polymerase (gp43) of T4-related phages. Vasiliy M Petrov, Swarnamala Ratnayaka, Jim D Karam Journal of molecular biology 2010 complete Vasiliy M Petrov*
Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex. Eric B Lansdon, Dharmaraj Samuel, Leanna Lagpacan, Katherine M Brendza, Kirsten L White, Magdeleine Hung, Xiaohong Liu, Constantine G Boojamra, Richard L Mackman, Tomas Cihlar, Adrian S Ray, Mary E McGrath, S Swaminathan Journal of molecular biology 2010 complete Eric B Lansdon*
Construction and validation of a yeast model system for studying in vivo the susceptibility to nucleoside analogues of DNA polymerase gamma allelic variants. Enrico Baruffini, Tiziana Lodi Mitochondrion 2010 complete Enrico Baruffini*
Coordinating DNA polymerase traffic during high and low fidelity synthesis. Mark D Sutton Biochimica et biophysica acta 2010 pols set
Continued primer synthesis at stalled replication forks contributes to checkpoint activation. Christopher Van, Shan Yan, W Matthew Michael, Shou Waga, Karlene A Cimprich J Cell Biol 2010 complete Karlene A Cimprich*
Probing the interaction of archaeal DNA polymerases with deaminated bases using X-ray crystallography and non-hydrogen bonding isosteric base analogues. Tom Killelea, Samantak Ghosh, Samuel S Tan, Pauline Heslop, Susan J Firbank, Eric T Kool, Bernard A Connolly Biochemistry 2010 topics set
Each monomer of the dimeric accessory protein for human mitochondrial DNA polymerase has a distinct role in conferring processivity. Young-Sam Lee, Sujin Lee, Borries Demeler, Ian J Molineux, Kenneth A Johnson, Y Whitney Yin The Journal of biological chemistry 2010 new
Role of histidine 932 of the human mitochondrial DNA polymerase in nucleotide discrimination and inherited disease. Dipanwita Batabyal, Jessica L McKenzie, Kenneth A Johnson The Journal of biological chemistry 2010 new
Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid. G K Surya Prakash, Mikhail Zibinsky, Thomas G Upton, Boris A Kashemirov, Charles E McKenna, Keriann Oertell, Myron F Goodman, Vinod K Batra, Lars C Pedersen, William A Beard, David D Shock, Samuel H Wilson, George A Olah Proceedings of the National Academy of Sciences of the United States of America 2010 topics set
The kinetic and chemical mechanism of high-fidelity DNA polymerases. Kenneth A Johnson Biochimica et biophysica acta 2010 new
Computational model of hepatitis B virus DNA polymerase: molecular dynamics and docking to understand resistant mutations. Pankaj R Daga, Jinsong Duan, Robert J Doerksen Protein science : a publication of the Protein Society 2010 complete Robert J Doerksen*
Replication of individual DNA molecules under electronic control using a protein nanopore. Felix Olasagasti, Kate R Lieberman, Seico Benner, Gerald M Cherf, Joseph M Dahl, David W Deamer, Mark Akeson Nature nanotechnology 2010 topics set
Lersivirine: a Non-Nucleoside Reverse Transcriptase Inhibitor with Activity against Drug-Resistant Human Immunodeficiency Virus-1. Romuald Corbau, Julie Mori, Chris Phillips, Lesley Fishburn, Alex Martin, Charles Mowbray, Wendy Panton, Caroline Smith-Burchnell, Adele Thornberry, Heather Ringrose, Thorsten Knöchel, Steve Irving, Mike Westby, Anthony Wood, Manos Perros Antimicrob Agents Chemother 2010 complete Romuald Corbau*
Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase. Samra Obeid, Anna Baccaro, Wolfram Welte, Kay Diederichs, Andreas Marx Proceedings of the National Academy of Sciences of the United States of America 2010 complete Andreas Marx*
Nature, position, and frequency of mutations made in a single cycle of HIV-1 replication. Michael E Abram, Andrea L Ferris, Wei Shao, W Gregory Alvord, Stephen H Hughes Journal of virology 2010 topics set
Inhibition of short patch and long patch base excision repair by an oxidized abasic site. Lirui Guan, Katarzyna Bebenek, Thomas A Kunkel, Marc M Greenberg Biochemistry 2010 topics set
Reversal of a mutator activity by a nearby fidelity-neutral substitution in the RB69 DNA polymerase binding pocket. Anna Trzemecka, Agata Jacewicz, Geraldine T Carver, John W Drake, Anna Bebenek Journal of molecular biology 2010 pols set
Optimization of DNA polymerase mutation rates during bacterial evolution. Ern Loh, Jesse J Salk, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 2010 new
Differential correction of lagging-strand replication errors made by DNA polymerases {alpha} and {delta}. Stephanie A Nick McElhinny, Grace E Kissling, Thomas A Kunkel Proceedings of the National Academy of Sciences of the United States of America 2010 new
A new model for SOS-induced mutagenesis: how RecA protein activates DNA polymerase V. Meghna Patel, Qingfei Jiang, Roger Woodgate, Michael M Cox, Myron F Goodman Crit Rev Biochem Mol Biol 2010 new
Sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO) in a sibling pair with a homozygous p.A467T POLG mutation. John C McHugh, Roisin Lonergan, Rachel Howley, Killian O'Rourke, Robert W Taylor, Michael Farrell, Michael Hutchinson, Sean Connolly Muscle & nerve 2010 pols set
A single mutation in human mitochondrial DNA polymerase Pol gammaA affects both polymerization and proofreading activities of only the holoenzyme. Young-Sam Lee, Kenneth A Johnson, Ian J Molineux, Y Whitney Yin The Journal of biological chemistry 2010 new
Error-free replicative bypass of (6-4) photoproducts by DNA polymerase zeta in mouse and human cells. Jung-Hoon Yoon, Louise Prakash, Satya Prakash Genes Dev 2010 new
A sulfoglycolipid beta-sulfoquinovosyldiacylglycerol (betaSQDG) binds to Met1-Arg95 region of murine DNA polymerase lambda (Mmpol lambda) and inhibits its nuclear transit. K Takakusagi, Yoichi Takakusagi, Keisuke Ohta, Satoko Aoki, Fumio Sugawara, Kengo Sakaguchi Protein Eng Des Sel 2010 new
Loss of DNA polymerase zeta enhances spontaneous tumorigenesis. John P Wittschieben, Vaishali Patil, Veronika Glushets, Lisa J Robinson, Donna F Kusewitt, Richard D Wood Cancer research 2010 new
A nuclear family A DNA polymerase from Entamoeba histolytica bypasses thymine glycol. Guillermo Pastor-Palacios, Elisa Azuara-Liceaga, Luis G Brieba PLoS Negl Trop Dis 2010 new
Participation of DNA polymerase zeta in replication of undamaged DNA in Saccharomyces cerevisiae. Matthew R Northam, Heather A Robinson, Olga V Kochenova, Polina V Shcherbakova Genetics 2010 new
Base excision repair and design of small molecule inhibitors of human DNA polymerase beta. Samuel H Wilson, William A Beard, David D Shock, Vinod K Batra, Nisha A Cavanaugh, Rajendra Prasad, Esther W Hou, Yuan Liu, Kenjiro Asagoshi, Julie K Horton, Donna F Stefanick, Padmini S Kedar, Michael J Carrozza, Aya Masaoka, Michelle L Heacock Cell Mol Life Sci 2010 pols set
Conformational dynamics of bacteriophage T7 DNA polymerase and its processivity factor, Escherichia coli thioredoxin. Barak Akabayov, Sabine R Akabayov, Seung-Joo Lee, Stanley Tabor, Arkadiusz W Kulczyk, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 2010 pols set
Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors. Hua-Poo Su, Youwei Yan, G Sridhar Prasad, Robert F Smith, Christopher L Daniels, Pravien D Abeywickrema, John C Reid, H Marie Loughran, Maria Kornienko, Sujata Sharma, Jay A Grobler, Bei Xu, Vinod Sardana, Timothy J Allison, Peter D Williams, Paul L Darke, Daria J Hazuda, Sanjeev Munshi J Virol 2010 partial results
Stable interaction between the human proliferating cell nuclear antigen loader complex Ctf18-replication factor C (RFC) and DNA polymerase {epsilon} is mediated by the cohesion-specific subunits, Ctf18, Dcc1, and Ctf8. Takeshi Murakami, Ryuji Takano, Satoshi Takeo, Rina Taniguchi, Kaori Ogawa, Eiji Ohashi, Toshiki Tsurimoto The Journal of biological chemistry 2010 new
N1-Alkyl pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Michael L Mitchell, Jong Chan Son, Hongyan Guo, Yun-A Im, Eun Jung Cho, Jianhong Wang, Jaclyn Hayes, Michael Wang, Amber Paul, Eric B Lansdon, James M Chen, Doris Graupe, Gerry Rhodes, Gong-Xin He, Romas Geleziunas, Lianhong Xu, Choung U Kim Bioorganic & medicinal chemistry letters 2010 partial results
Mitochondrial DNA polymerase POLIB is essential for minicircle DNA replication in African trypanosomes. David F Bruhn, Brian Mozeleski, Laurie Falkin, Michele M Klingbeil Molecular microbiology 2010 new
Identification of critical residues for the tight binding of both correct and incorrect nucleotides to human DNA polymerase lambda. Jessica A Brown, Lindsey R Pack, Shanen M Sherrer, Ajay K Kshetry, Sean A Newmister, Jason D Fowler, John-Stephen Taylor, Zucai Suo Journal of molecular biology 2010 pols set
Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy. Jingsong Yang, J Parsons, Nils H Nicolay, S Caporali, C F Harrington, R Singh, D Finch, S D'Atri, P B Farmer, P G Johnston, W Gillies McKenna, G Dianov, Ricky A Sharma Oncogene 2010 new
Computational delineation of the catalytic step of a high-fidelity DNA polymerase. Ravindra Venkatramani, Ravi Radhakrishnan Protein science : a publication of the Protein Society 2010 new
Accurate DNA synthesis by Sulfolobus solfataricus DNA polymerase B1 at high temperature. Likui Zhang, Huiqiang Lou, Li Guo, Zhengyan Zhan, Zhenhong Duan, Xin Guo, Li Huang Extremophiles 2010 pols set
Thioredoxin suppresses microscopic hopping of T7 DNA polymerase on duplex DNA. Candice M Etson, Samir M Hamdan, Charles C Richardson, Antoine M van Oijen Proceedings of the National Academy of Sciences of the United States of America 2010 pols set
Host-specific replication of BK virus DNA in mouse cell extracts is independently controlled by DNA polymerase alpha-primase and inhibitory activities. Irina Tikhanovich, Heinz Peter Nasheuer J Virol 2010 new
Incorporation of gemcitabine and cytarabine into DNA by DNA polymerase beta and ligase III/XRCC1. A S Prakasha Gowda, Joanna M Polizzi, Kristin A Eckert, Thomas E Spratt Biochemistry 2010 new
Characterisation of a DNA polymerase highly mutated along the template binding interface. Sophie Vichier-Guerre, Jean-Luc Jestin Mol Biotechnol 2010 pols set
Regulation of DNA polymerase POLD4 influences genomic instability in lung cancer. Qin Miao Huang, Shuta Tomida, Yuji Masuda, Chinatsu Arima, Ke Cao, Taka-Aki Kasahara, Hirotaka Osada, Yasushi Yatabe, Tomohiro Akashi, Kenji Kamiya, Tomonori Takahashi, Motoshi Suzuki Cancer research 2010 new
Functional analysis of H. sapiens DNA polymerase gamma spacer mutation W748S with and without common variant E1143G. Eino J H Palin, Annamari Lesonen, Carol L Farr, Liliya Euro, Anu Suomalainen, Laurie S Kaguni Biochimica et biophysica acta 2010 pols set
The mitochondrial DNA polymerase in health and disease. William C Copeland Subcell Biochem 2010 new
Only one ATP-binding DnaX subunit is required for initiation complex formation by the Escherichia coli DNA polymerase III holoenzyme. Anna Wieczorek, Christopher D Downey, H Garry Dallmann, Charles S McHenry The Journal of biological chemistry 2010 pols set
Purification and functional characterization of human mitochondrial DNA polymerase gamma harboring disease mutations. Rajesh Kasiviswanathan, Matthew J Longley, Matthew J Young, William C Copeland Methods 2010 new
Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange. Bret D Freudenthal, Lokesh Gakhar, S Ramaswamy, M Todd Washington Nature structural & molecular biology 2010 new
A specific docking site for DNA polymerase {alpha}-primase on the SV40 helicase is required for viral primosome activity, but helicase activity is dispensable. Hao Huang, Kun Zhao, Diana R Arnett, Ellen Fanning The Journal of biological chemistry 2010 new
Hinge residue I174 is critical for proper dNTP selection by DNA polymerase beta. Jen Yamtich, Daniela Starcevic, Julia M Lauper, Elenoe Smith, Idina Shi, Sneha Rangarajan, Joachim Jaeger, Joann B Sweasy Biochemistry 2010 partial results
Residue 752 in DNA polymerase of equine herpesvirus type 1 is non-essential for virus growth in vitro. Guanggang Ma, Chengping Lu, Nikolaus Osterrieder The Journal of general virology 2010 new
Regulation of translesion synthesis DNA polymerase eta by monoubiquitination. Marzena Bienko, Catherine M Green, Simone Sabbioneda, Nicola Crosetto, Ivan Matic, Richard G Hibbert, Tihana Begovic, Atsuko Niimi, Matthias Mann, Alan R Lehmann, Ivan Dikic Molecular cell 2010 new
Crystal Structure of a Cisplatin-(1,3-GTG) Cross-Link within DNA Polymerase eta. Thomas Reissner, Sabine Schneider, Stephanie Schorr, Thomas Carell Angew Chem Int Ed Engl 2010 topics set
Poly(ADP-ribose) polymerase 1 regulates activity of DNA polymerase beta in long patch base excision repair. Maria V Sukhanova, Svetlana N Khodyreva, Olga I Lavrik Mutation research 2010 new
Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin. Pierre Aller, Yu Ye, Susan S Wallace, Cynthia J Burrows, Sylvie Doublié Biochemistry 2010 topics set
Unconventional ubiquitin recognition by the ubiquitin-binding motif within the Y family DNA polymerases iota and Rev1. Martha G Bomar, Sanjay D'Souza, Marzena Bienko, Ivan Dikic, Graham C Walker, Pei Zhou Molecular cell 2010 topics set
Attomole detection of mesophilic DNA polymerase products by nanoparticle-enhanced surface plasmon resonance imaging on glassified gold surfaces. Lida K Gifford, Iuliana E Sendroiu, Robert M Corn, Andrej Lupták Journal of the American Chemical Society 2010 new
Replication through an abasic DNA lesion: structural basis for adenine selectivity. Samra Obeid, Nina Blatter, Ramon Kranaster, Andreas Schnur, Kay Diederichs, Wolfram Welte, Andreas Marx The EMBO journal 2010 topics set
Unwinding of zinc finger domain of DNA polymerase I by cis-diamminedichloroplatinum(II). Leila Maurmann, Rathindra N Bose Dalton Trans 2010 new
Effect of acyclovir on HIV-1 set point among herpes simplex virus type 2-seropositive persons during early HIV-1 infection. H Nina Kim, Jing Wang, James Hughes, Robert Coombs, Jorge Sanchez, Stewart Reid, Sinead Delany-Moretlwe, Frances Cowan, Jonathan Fuchs, Susan H Eshleman, Leila Khaki, Moira A McMahon, Robert F Siliciano, Anna Wald, Connie Celum The Journal of infectious diseases 2010 pols set
Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4. Olga Rechkoblit, Alexander Kolbanovskiy, Lucy Malinina, Nicholas E Geacintov, Suse Broyde, Dinshaw J Patel Nature structural & molecular biology 2010 topics set
Kinetic basis of sugar selection by a Y-family DNA polymerase from Sulfolobus solfataricus P2. Shanen M Sherrer, David C Beyer, Cynthia X Xia, Jason D Fowler, Zucai Suo Biochemistry 2010 pols set
Characterization of physical and functional interactions between eukaryote-like Orc1/Cdc6 proteins and Y-family DNA polymerase in the hyperthermophilic archaeon Sulfolobus solfataricus. Shifan Yang, Hongchao Gong, Lu Zhang, Yi Liu, Zheng-Guo He Biochem Biophys Res Commun 2010 new
Crystal Structure of HIV-1 Reverse Transcriptase Bound to a Non-Nucleoside Inhibitor with a Novel Mechanism of Action. Séverine Freisz, Guillaume Bec, Marco Radi, Philippe Wolff, Emmanuele Crespan, Lucilla Angeli, Philippe Dumas, Giovanni Maga, Maurizio Botta, Eric Ennifar Angew Chem Int Ed Engl 2010 partial results
DNA polymerase beta ribonucleotide discrimination: insertion, misinsertion, extension, and coding. Nisha A Cavanaugh, William A Beard, Samuel H Wilson The Journal of biological chemistry 2010 new
Molecular characterization of a distinct begomovirus species from Vernonia cinerea and its associated DNA-beta using the bacteriophage Phi 29 DNA polymerase. R M Packialakshmi, N Srivastava, K R Girish, R Usha Virus genes 2010 new
Parallel multiplicative target screening against divergent bacterial replicases: identification of specific inhibitors with broad spectrum potential. H Garry Dallmann, Oliver J Fackelmayer, Guy Tomer, Joe Chen, Anna Wiktor-Becker, Tracey Ferrara, Casey Pope, Marcos T Oliveira, Peter M J Burgers, Laurie S Kaguni, Charles S McHenry Biochemistry 2010 new
Pirh2 E3 ubiquitin ligase targets DNA polymerase eta for 20S proteasomal degradation. Yong-Sam Jung, Gang Liu, Xinbin Chen Molecular and cellular biology 2010 topics set
Potentiation of temozolomide cytotoxicity by inhibition of DNA polymerase beta is accentuated by BRCA2 mutation. Gregory C Stachelek, Shibani Dalal, Katherine A Donigan, Denise Campisi Hegan, Joann B Sweasy, Peter M Glazer Cancer research 2010 new
The mechanism of the translocation step in DNA replication by DNA polymerase I: a computer simulation analysis. Andrei A Golosov, Joshua J Warren, Lorena S Beese, Martin Karplus Structure (London, England : 1993) 2010 topics set
Structural basis for the suppression of skin cancers by DNA polymerase eta. Timothy D Silverstein, Robert E Johnson, Rinku Jain, Louise Prakash, Satya Prakash, Aneel K Aggarwal Nature 2010 topics set
Enhancement of human cancer cell radiosensitivity by conjugated eicosapentaenoic acid - a mammalian DNA polymerase inhibitor. Yuko Kumamoto-Yonezawa, Ryohei Sasaki, Yoko Suzuki, Yuki Matsui, Takahiko Hada, Keisuke Uryu, Kazuro Sugimura, Hiromi Yoshida, Yoshiyuki Mizushina Int J Oncol 2010 pols set
Effect of 8-oxoguanine and abasic site DNA lesions on in vitro elongation by human DNA polymerase in the presence of replication protein A and proliferating-cell nuclear antigen. Giada A Locatelli, Helmut Pospiech, Nicolas Tanguy Le Gac, Barbara van Loon, Ulrich Hubscher, Sinikka Parkkinen, Juhani E Syväoja, Giuseppe Villani Biochem J 2010 new
[Analysis of mutations in DNA polymerase and thymidine kinase genes of herpes simplex virus clinical isolates resistant to antiherpetic drugs]. A N Korovina, A A Gus'kova, M Iu Skoblov, V L Andronova, G A Galegov, S N Kochetkov, M K Kukhanova, Iu S Skoblov Mol Biol (Mosk) 2010 new
DNA polymerase POLN participates in cross-link repair and homologous recombination. George-Lucian Moldovan, Mahesh V Madhavan, Kanchan D Mirchandani, Ryan M McCaffrey, Patrizia Vinciguerra, Alan D D'Andrea Molecular and cellular biology 2010 new
Interaction of the human cytomegalovirus uracil DNA glycosylase UL114 with the viral DNA polymerase catalytic subunit UL54. Blair L Strang, Donald M Coen The Journal of general virology 2010 new
Structures of DNA polymerases caught processing size-augmented nucleotide probes. Karin Betz, Frank Streckenbach, Andreas Schnur, Thomas Exner, Wolfram Welte, Kay Diederichs, Andreas Marx Angew Chem Int Ed Engl 2010 topics set
Halogenated beta,gamma-methylene- and ethylidene-dGTP-DNA ternary complexes with DNA polymerase beta: structural evidence for stereospecific binding of the fluoromethylene analogues. Vinod K Batra, Lars C Pedersen, William A Beard, Samuel H Wilson, Boris A Kashemirov, Thomas G Upton, Myron F Goodman, Charles E McKenna Journal of the American Chemical Society 2010 topics set
Study on steady-state kinetics of nucleotide analogues incorporation by non-gel CE. Wujie Li, Mou Cao, Lu Pei, Xiaomei Ling, Bingchao Li, Zhenjun Yang Electrophoresis 2010 partial results
Mutation in the catalytic subunit of DNA polymerase alpha influences transcriptional gene silencing and homologous recombination in Arabidopsis. Jianhua Liu, Xiaozhi Ren, Haibo Yin, Yu Wang, Ran Xia, Youqun Wang, Zhizhong Gong Plant J 2010 new
Identification of a new motif in family B DNA polymerases by mutational analyses of the bacteriophage t4 DNA polymerase. Vincent Li, Matthew Hogg, Linda J Reha-Krantz Journal of molecular biology 2010 complete
Replacing 32 proline residues by a noncanonical amino acid results in a highly active DNA polymerase. Bastian Holzberger, Andreas Marx Journal of the American Chemical Society 2010 topics set
DNA polymerase proofreading: Multiple roles maintain genome stability. Linda J Reha-Krantz Biochimica et biophysica acta 2010 complete
A mechanistic view of human mitochondrial DNA polymerase gamma: providing insight into drug toxicity and mitochondrial disease. Christopher M Bailey, Karen S Anderson Biochimica et biophysica acta 2010 new
[Investigation of the interaction of repair DNA polymerase beta and autonomous 3' --> 5'-exonucleases TREX1 and TREX2]. N V Beliakova, O K Legina, N L Ronzhina, Igor V Shevelev, V M Krutiakov Izv Akad Nauk Ser Biol 2010 new
A new thermostable DNA polymerase mixture for efficient amplification of long DNA fragments. K G Davalieva, G D Efremov Prikl Biokhim Mikrobiol 2010 pols set
Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase eta. Timothy D Silverstein, Rinku Jain, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Structure (London, England : 1993) 2010 topics set
Consecutive incorporation of fluorophore-labeled nucleotides by mammalian DNA polymerase beta. Ken Hirano, Yuichiro Yoshida, Tomomi Ishido, Yukihisa Wada, Naoji Moriya, Naoshi Yamazaki, Yoshiyuki Mizushina, Yoshinobu Baba, Mitsuru Ishikawa Anal Biochem 2010 topics set
A DNA polymerase with increased reactivity for ribonucleotides and C5-modified deoxyribonucleotides. Nadine Staiger, Andreas Marx Chembiochem 2010 new
An amino acid residue in the middle of the fingers subdomain is involved in Neq DNA polymerase processivity: enhanced processivity of engineered Neq DNA polymerase and its PCR application. Jae-Geun Song, Eui-Joon Kil, Sung Suk Cho, In Hye Kim, Suk-Tae Kwon Protein Eng Des Sel 2010 new
Inhibitory effects of sulfobacin B on DNA polymerase and inflammation. Jun Maeda, Masayuki Nishida, Hirosato Takikawa, Hiromi Yoshida, Takeshi Azuma, Masaru Yoshida, Yoshiyuki Mizushina Int J Mol Med 2010 new
Structural basis for proficient incorporation of dTTP opposite O6-methylguanine by human DNA polymerase iota. Matthew G Pence, Jeong-Yun Choi, Martin Egli, F Peter Guengerich The Journal of biological chemistry 2010 pols set
Effect of N2-guanyl modifications on early steps in catalysis of polymerization by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W. Haijiang Zhang, F Peter Guengerich Journal of molecular biology 2010 new
Polymerization by DNA polymerase eta is blocked by cis-diamminedichloroplatinum(II) 1,3-d(GpTpG) cross-link: implications for cytotoxic effects in nucleotide excision repair-negative tumor cells. Shotaro Chijiwa, Chikahide Masutani, Fumio Hanaoka, Shigenori Iwai, Isao Kuraoka Carcinogenesis 2010 new
A highly active DNA polymerase with a fluorous core. Bastian Holzberger, Marina Rubini, Heiko M Möller, Andreas Marx Angew Chem Int Ed Engl 2010 new
Irreversible inhibition of DNA polymerase beta by an oxidized abasic lesion. Lirui Guan, Marc M Greenberg Journal of the American Chemical Society 2010 new
Structure of a DNA polymerase alpha-primase domain that docks on the SV40 helicase and activates the viral primosome. Hao Huang, Brian E Weiner, Haijiang Zhang, Brian E Fuller, Yue Gao, Brian M Wile, Kun Zhao, Diana R Arnett, Walter J Chazin, Ellen Fanning The Journal of biological chemistry 2010 new
Association between the herpes simplex virus-1 DNA polymerase and uracil DNA glycosylase. Federica Bogani, Ilsa Corredeira, Virneliz Fernandez, Ulrike Sattler, Wiriya Rutvisuttinunt, Martine Defais, Paul E Boehmer The Journal of biological chemistry 2010 new
Mutagenic conformation of 8-oxo-7,8-dihydro-2'-dGTP in the confines of a DNA polymerase active site. Vinod K Batra, William A Beard, Esther W Hou, Lars C Pedersen, Rajendra Prasad, Samuel H Wilson Nature structural & molecular biology 2010 new
Replication factor C recruits DNA polymerase delta to sites of nucleotide excision repair but is not required for PCNA recruitment. René M Overmeer, Audrey M Gourdin, Ambra Giglia-Mari, Hanneke Kool, Adriaan B Houtsmuller, Gregg Siegal, Maria I Fousteri, Leon H F Mullenders, Wim Vermeulen Molecular and cellular biology 2010 new
Opposite effect of two cytomegalovirus DNA polymerase mutations on replicative capacity and polymerase activity. Mélanie Martin, Arezki Azzi, Sheng-Xiang Lin, Guy Boivin Antivir Ther 2010 new
DNA polymerase fidelity: comparing direct competition of right and wrong dNTP substrates with steady state and pre-steady state kinetics. Jeffrey G Bertram, Keriann Oertell, John Petruska, Myron F Goodman Biochemistry 2010 new
Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin . Jeff W Beckman, Michael Wang, Gregor Blaha, Jianhong Wang, William H Konigsberg Biochemistry 2010 topics set
Pre-steady state kinetic studies of the fidelity of nucleotide incorporation by yeast DNA polymerase delta. Lynne M Dieckman, Robert E Johnson, Satya Prakash, M Todd Washington Biochemistry 2010 new
Effect of human cell malignancy on activity of DNA polymerase iota. Andrey A Kazakov, E E Grishina, Vyacheslav Z Tarantul, Leonid V Gening Biochemistry (Mosc) 2010 new
phi29 DNA polymerase active site: role of residue Val250 as metal-dNTP complex ligand and in protein-primed initiation. Patricia Pérez-Arnaiz, José María Lázaro, Margarita Salas, Miguel de Vega Journal of molecular biology 2010 topics set
Improvement of phi29 DNA polymerase amplification performance by fusion of DNA binding motifs. Miguel de Vega, José María Lázaro, Mario Mencía, Luis Blanco, Margarita Salas Proceedings of the National Academy of Sciences of the United States of America 2010 pols set
DNA polymerase eta lacking the ubiquitin-binding domain promotes replicative lesion bypass in humans cells. Narottam Acharya, Jung-Hoon Yoon, Jerard Hurwitz, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2010 new
DNA polymerase-beta is required for 1-methyl-4-phenylpyridinium-induced apoptotic death in neurons. Zhentao Zhang, Xuebing Cao, Nian Xiong, Hongcai Wang, Jinsha Huang, Shenggang Sun, Zhihou Liang, Tao Wang Apoptosis 2010 new
Targeted radiosensitization of cells expressing truncated DNA polymerase {beta}. Sari Neijenhuis, Manon Verwijs-Janssen, Lenie J van den Broek, Adrian C Begg, Conchita Vens Cancer research 2010 new
Telomere healing following DNA polymerase arrest-induced breakages is likely the main mechanism generating chromosome 4p terminal deletions. Femke Hannes, Jeroen Van Houdt, Oliver W Quarrell, Martin Poot, Ron Hochstenbach, Jean-Pierre Fryns, Joris R Vermeesch Hum Mutat 2010 topics set
Hybrid diarylbenzopyrimidine non-nucleoside reverse transcriptase inhibitors as promising new leads for improved anti-HIV-1 chemotherapy. Zhao-Sen Zeng, Qiu-Qin He, Yong-Hong Liang, Xiao-Qing Feng, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Bioorganic & medicinal chemistry 2010 pols set
The mutation T477A in HIV-1 reverse transcriptase (RT) restores normal proteolytic processing of RT in virus with Gag-Pol mutated in the p51-RNH cleavage site. Michael E Abram, Stefan G Sarafianos, Michael A. Parniak Retrovirology 2010 pols set
Comparison of the in vitro replication of the 7-(2-oxoheptyl)-1,N2-etheno-2'-deoxyguanosine and 1,N2-etheno-2'-deoxyguanosine lesions by Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4). Plamen P Christov, Katya V Petrova, Ganesh Shanmugam, Ivan D Kozekov, Albena Kozekova, F Peter Guengerich, Michael P Stone, Carmelo J Rizzo Chemical research in toxicology 2010 new
Structural basis of HIV-1 resistance to AZT by excision. Xiongying Tu, Kalyan Das, Qianwei Han, Joseph David Bauman, Arthur D Clark, Xiaorong Hou, Yulia Volovik Frenkel, Barbara L Gaffney, Roger A Jones, Paul L Boyer, Stephen H Hughes, Stefan G Sarafianos, Edward Arnold Nature structural & molecular biology 2010 pols set
Non-nucleoside HIV-1 reverse transcriptase inhibitors di-halo-indolyl aryl sulfones achieve tight binding to drug-resistant mutants by targeting the enzyme-substrate complex. Alberta Samuele, Alexandra Kataropoulou, Marco Viola, Samantha Zanoli, Giuseppe La Regina, Francesco Piscitelli, Romano Silvestri, Giovanni Maga Antiviral research 2009 pols set
Role of DNA damage-induced replication checkpoint in promoting lesion bypass by translesion synthesis in yeast. Vincent Pagès, Sergio R Santa Maria, Louise Prakash, Satya Prakash Genes & development 2009 new
A slow ATP-induced conformational change limits the rate of DNA binding but not the rate of beta clamp binding by the escherichia coli gamma complex clamp loader. Jennifer A Thompson, Christopher O Paschall, Mike E O'Donnell, Linda B Bloom The Journal of biological chemistry 2009 complete Linda B Bloom*
Translesion DNA synthesis by human DNA polymerase eta on templates containing a pyrimidopurinone deoxyguanosine adduct, 3-(2'-deoxy-beta-d-erythro-pentofuranosyl)pyrimido-[1,2-a]purin-10(3H)-one . Jennifer B Stafford, Robert Lawton Eoff, Albena Kozekova, Carmelo J Rizzo, F Peter Guengerich, Lawrence J Marnett Biochemistry 2009 pols set
Visualizing sequence-governed nucleotide selectivities and mutagenic consequences through a replicative cycle: processing of a bulky carcinogen N2-dG lesion in a Y-family DNA polymerase. Pingna Xu, Lida Oum, Yuan-Cho Lee, Nicholas E Geacintov, Suse Broyde Biochemistry 2009 new
Preparation of long sticky ends for universal ligation-independent cloning: sequential T4 DNA polymerase treatments. Akira Tachibana, Kazuo Tohiguchi, Takayuki Ueno, Yuichi Setogawa, Ayako Harada, Toshizumi Tanabe J Biosci Bioeng 2009 pols set
Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance. Lauren S Waters, Brenda K Minesinger, Mary Ellen Wiltrout, Sanjay D'Souza, Rachel V Woodruff, Graham C Walker Microbiol Mol Biol Rev 2009 topics set
Treatment of injured neurons with bone marrow stem cells cotransfected by hTERT and Ad-BDNF in vitro. Zhengqiang Wang, Quanjun Deng, Xiaohui Zhang, Jianning Zhang Journal of molecular neuroscience : MN 2009 new
Low-fidelity DNA synthesis by the L979F mutator derivative of Saccharomyces cerevisiae DNA polymerase zeta. Jana E Stone, Grace E Kissling, Scott A Lujan, Igor B Rogozin, Carrie M W Stith, Peter M J Burgers, Thomas A Kunkel Nucleic acids research 2009 pols set
A cluster of polypyrimidine tracts is involved in the transcription regulation of telomerase transcriptional elements-interacting factor. Ying Sun, Qian Sun, Michael A McNutt, Yilei Gong, Jiaochen Wang, Lin Hou, Qi Shen, Yun Ling, Yingkai Chi, Bo Zhang Molecular and cellular biochemistry 2009 new
Ambivalent incorporation of the fluorescent cytosine analogues tC and tCo by human DNA polymerase alpha and Klenow fragment. Gudrun Stengel, Byron W Purse, L Marcus Wilhelmsson, Milan Urban, Robert D Kuchta Biochemistry 2009 topics set
Sliding clamp-DNA interactions are required for viability and contribute to DNA polymerase management in Escherichia coli. Justin M H Heltzel, Sarah K Scouten Ponticelli, Laurie H Sanders, Jill M Duzen, Vivian Cody, James Pace, Edward H Snell, Mark D Sutton Journal of molecular biology 2009 topics set
Structural determinant for switching between the polymerase and exonuclease modes in the PCNA-replicative DNA polymerase complex. Hirokazu Nishida, Kouta Mayanagi, Shinichi Kiyonari, Yuichi Sato, Takuji Oyama, Yoshizumi Ishino, Kosuke Morikawa Proceedings of the National Academy of Sciences of the United States of America 2009 new
Rescue of bacteriophage T7 DNA polymerase of low processivity by suppressor mutations affecting gene 3 endonuclease. Seung-Joo Lee, Kajal Chowdhury, Stanley Tabor, Charles C Richardson Journal of virology 2009 topics set
Identifying the features of purine dNTPs that allow accurate and efficient DNA replication by herpes simplex virus I DNA polymerase. Nisha A Cavanaugh, Milan Urban, Jeffrey Beckman, Thomas E Spratt, Robert D Kuchta Biochemistry 2009 new
[Study on the transmission of drug resistant human immunodeficiency virus-1 in Henan province]. Yuan Yuan, Xin-liang Cao, Hong-wei Liu, Hui Xing, Chun-hua Liu, Wei-guo Cui, Ding-yong Sun, Ning Li, Qian Zhu, Zhengqiang Wang, Yi-ming Shao Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 2009 new
DNA polymerase mu interacts with a meiosis-specific RecA homolog Lim15 during meiosis in Coprinus cinereus. Takuro Yanai, Aiko Sakamoto, Kazuki Iwabata, Akiyo Koshiyama, Hiroko Sugawara, Takayuki Nara, Yoichi Takakusagi, Kengo Sakaguchi Biochem Biophys Res Commun 2009 new
Ctf4 coordinates the progression of helicase and DNA polymerase alpha. Hiromichi Tanaka, Yuki Katou, Masaru Yagura, Katsuya Saitoh, Takehiko Itoh, Hiroyuki Araki, Masashige Bando, Katsuhiko Shirahige Genes Cells 2009 new
Interaction of human DNA polymerase alpha and DNA polymerase I from Bacillus stearothermophilus with hypoxanthine and 8-oxoguanine nucleotides. Jennifer N Patro, Milan Urban, Robert D Kuchta Biochemistry 2009 pols set
Mutational analysis of the HIV-1 auxiliary protein Vif identifies independent domains important for the physical and functional interaction with HIV-1 reverse transcriptase. Alexandra Kataropoulou, Chiara Bovolenta, Amalia Belfiore, Sonia Trabatti, Anna Garbelli, Simona Porcellini, Rossella Lupo, Giovanni Maga Nucleic acids research 2009 pols set
The essential role of p53 in hyperpigmentation of the skin via regulation of paracrine melanogenic cytokine receptor signaling. Daiki Murase, Akira Hachiya, Yasuko Amano, Atsushi Ohuchi, Takashi Kitahara, Yoshinori Takema The Journal of biological chemistry 2009 new
Analysis of mutant DNA polymerase gamma in patients with mitochondrial DNA depletion. Jan-Willem Taanman, Shamima Rahman, Alistair T Pagnamenta, Andrew A M Morris, Maria Bitner-Glindzicz, Nicole I Wolf, James V Leonard, Peter T Clayton, Anthony H V Schapira Hum Mutat 2009 pols set
Structural basis for novel interactions between human translesion synthesis polymerases and proliferating cell nuclear antigen. Asami Hishiki, Hiroshi Hashimoto, Tomo Hanafusa, Keijiro Kamei, Eiji Ohashi, Toshiyuki Shimizu, Haruo Ohmori, Mamoru Sato The Journal of biological chemistry 2009 topics set
Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammals. Sigal Shachar, Omer Ziv, Sharon Avkin, Sheera Adar, John P Wittschieben, Thomas Reissner, Stephen Chaney, Errol C Friedberg, Zhengqiang Wang, Thomas Carell, Nicholas E Geacintov, Zvi Livneh The EMBO journal 2009 topics set
Synthesis and structure-activity relationships of dehydroaltenusin derivatives as selective DNA polymerase alpha inhibitors. Kouji Kuramochi, Keishi Fukudome, Isoko Kuriyama, Toshifumi Takeuchi, Yoshihiro Sato, Shinji Kamisuki, Kazunori Tsubaki, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Bioorg Med Chem 2009 pols set
Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases. Hana Macícková-Cahová, Michal Hocek Nucleic acids research 2009 topics set
The family X DNA polymerase from Deinococcus radiodurans adopts a non-standard extended conformation. Nicolas Leulliot, Lionel Cladière, François Lecointe, Dominique Durand, Ulrich Hübscher, Herman van Tilbeurgh The Journal of biological chemistry 2009 topics set
Single molecule measurement of the "speed limit" of DNA polymerase. Jerrod J Schwartz, Stephen R Quake Proceedings of the National Academy of Sciences of the United States of America 2009 new
Steric constraints dependent on nucleobase pair orientation vary in different DNA polymerase active sites. Frank Streckenbach, Gopinath Rangam, Heiko M Möller, Andreas Marx Chembiochem 2009 new
Crystal structure of a trypanocidal 4,4'-bis(imidazolinylamino)diphenylamine bound to DNA. LaTeca S Glass, Binh Nguyen, Kristie D Goodwin, Christophe Dardonville, W David Wilson, Eric C Long, Millie M Georgiadis Biochemistry 2009 topics set
Proofreading exonuclease activity of human DNA polymerase delta and its effects on lesion-bypass DNA synthesis. Ruzaliya Fazlieva, Cynthia S Spittle, Darlene Morrissey, Harutoshi Hayashi, Hong Yan, Yoshihiro Matsumoto Nucleic acids research 2009 pols set
Interaction with DNA polymerase eta is required for nuclear accumulation of REV1 and suppression of spontaneous mutations in human cells. Jun-Ichi Akagi, Chikahide Masutani, Yuki Kataoka, Takashi Kan, Eiji Ohashi, Toshio Mori, Haruo Ohmori, Fumio Hanaoka DNA repair 2009 new
Enzymatic synthesis of perfluoroalkylated DNA. Bastian Holzberger, Andreas Marx Bioorganic & medicinal chemistry 2009 new
Insights into the high fidelity of a DNA polymerase I mutant. Thomas E Exner J Mol Model 2009 pols set
Competitive inhibition of uracil DNA glycosylase by a modified nucleotide whose triphosphate is a substrate for DNA polymerase. Haidong Huang, James T Stivers, Marc M Greenberg Journal of the American Chemical Society 2009 pols set
Synthesis and DNA polymerase alpha and beta inhibitory activity of alkyl p-coumarates and related compounds. Katsumi Nishimura, Yukiko Takenaka, Manami Kishi, Takao Tanahashi, Hiromi Yoshida, Chiaki Okuda, Yoshiyuki Mizushina Chem Pharm Bull (Tokyo) 2009 new
Effect of testosterone on E1S-sulfatase activity in non-malignant and cancerous breast cells in vitro. Matthias Götte, Kathrin Kalkhake, Sebastian Ploeger, Ludwig Kiesel, Petra Stute J Steroid Biochem Mol Biol 2009 new
Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA. Guangxin Xing, Kevin N Kirouac, Yoon Jung Shin, Stephen D Bell, Hong Ling Molecular microbiology 2009 topics set
Stroke work or systolic dP/dtmax to evaluate acute response to cardiac resynchronization therapy: are they interchangeable? Gerjan de Roest, Paul Knaapen, Matthias Götte, Thijs Hendriks, Cor P Allaart, Carel C de Cock, Albert C van Rossum Eur J Heart Fail 2009 new
Insights into the cellular role of enigmatic DNA polymerase iota. Antonio E Vidal, Roger Woodgate DNA repair 2009 pols set
Construction of a circular single-stranded DNA template containing a defined lesion. Kiyonobu Karata, Antonio E Vidal, Roger Woodgate DNA repair 2009 pols set
Phenotypic variations in 3 children with POLG1 mutations. Prinyarat Burusnukul, Emily C de los Reyes Journal of child neurology 2009 pols set
Loop II of DNA polymerase beta is important for discrimination during substrate binding. George C Lin, Joachim Jaeger, Kristin A Eckert, Joann B Sweasy DNA repair 2009 new
Structural insight into processive human mitochondrial DNA synthesis and disease-related polymerase mutations. Young-Sam Lee, W Dexter Kennedy, Y Whitney Yin Cell 2009 partial results
Two cases of development of entecavir resistance during entecavir treatment for nucleoside-naive chronic hepatitis B. Haruhiko Kobashi, Shin-ichi Fujioka, Mitsuhiko Kawaguchi, Hiromitsu Kumada, Osamu Yokosuka, Norio Hayashi, Kazuyuki Suzuki, Takeshi Okanoue, Michio Sata, Hirohito Tsubouchi, Chifumi Sato, Kendo Kiyosawa, Kyuichi Tanikawa, Taku Seriu, Hiroki Ishikawa, Akinobu Takaki, Yoshiaki Iwasaki, Toshiya Osawa, Toshiyuki Takaki, Kosaku Sakaguchi, Yasushi Shiratori, Kazuhide Yamamoto, Daniel J Tenney, Masao Omata Hepatology international 2009 new
Crystal structure analysis of DNA lesion repair and tolerance mechanisms. Sabine Schneider, Stephanie Schorr, Thomas Carell Current opinion in structural biology 2009 topics set
Augmentation of reverse transcription by integrase through an interaction with host factor, SIP1/Gemin2 Is critical for HIV-1 infection. Hironori Nishitsuji, Takaya Hayashi, Tomosaburo Takahashi, Masashi Miyano, Mari Kannagi, Takao Masuda PloS one 2009 complete Takao Masuda*
Efficient enzymatic synthesis of LNA-modified DNA duplexes using KOD DNA polymerase. Rakesh N Veedu, Birte Vester, Jesper Wengel Organic & biomolecular chemistry 2009 topics set
Amino acid architecture that influences dNTP insertion efficiency in Y-family DNA polymerase V of E. coli. Kwang Young Seo, Jun Yin, Prashant Donthamsetti, Sushil Chandani, Chui Hong Lee, Edward L Loechler Journal of molecular biology 2009 pols set
Multidrug-resistant variants of HIV type 1 (HIV-1) can exist in cells as defective quasispecies and be rescued by superinfection with other defective HIV-1 variants. Yudong Quan, Chen Liang, Bluma G Brenner, Mark A. Wainberg The Journal of infectious diseases 2009 pols set
Effect of A and B metal ion site occupancy on conformational changes in an RB69 DNA polymerase ternary complex. Michael Wang, Harold R Lee, William H Konigsberg Biochemistry 2009 complete
Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents. Anna-Maria Monforte, Patrizia Logoteta, Stefania Ferro, Laura De Luca, Nunzio Iraci, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri Bioorganic & medicinal chemistry 2009 pols set
Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis. Samir M Hamdan, Joseph J Loparo, Masateru Takahashi, Charles C Richardson, Antoine M van Oijen Nature 2009 new
Kinetic analysis of base-pairing preference for nucleotide incorporation opposite template pyrimidines by human DNA polymerase iota. Jeong-Yun Choi, Seonhee Lim, Robert Lawton Eoff, F Peter Guengerich Journal of molecular biology 2009 pols set
The resveratrol analogue 4,4'-dihydroxy-trans-stilbene inhibits cell proliferation with higher efficiency but different mechanism from resveratrol. Monica Savio, T Coppa, Livia Bianchi, Vanio Vannini, Giovanni Maga, L Forti, Ornella Cazzalini, M C Lazzè, Paola Perucca, Ennio Prosperi, Lucia A Stivala The international journal of biochemistry & cell biology 2009 new
Restoring 3'-5' exonuclease activity of thermophilic Geobacillus DNA polymerase I using site-directed mutagenesis in active site. Nasrin Rastgoo, Majid Sadeghizadeh, Bijan Bambaei, Saman Hosseinkhani J Biotechnol 2009 new
Engineering of a chimeric RB69 DNA polymerase sensitive to drugs targeting the cytomegalovirus enzyme. Egor P Tchesnokov, Aleksandr Obikhod, Raymond F Schinazi, Matthias Götte The Journal of biological chemistry 2009 topics set
Fatal congenital myopathy and gastrointestinal pseudo-obstruction due to POLG1 mutations. C Giordano, H Powell, M Leopizzi, M De Curtis, M de Curtis, C Travaglini, M Sebastiani, P Gallo, Robert W Taylor, G d'Amati Neurology 2009 pols set
[Research progress on DNA polymerase beta and genetic instability]. Mei Wu, Zhenzhong Zhang Wei sheng yan jiu = Journal of hygiene research 2009 topics set
A historical reflection on the discovery of human retroviruses. Anders Vahlne Retrovirology 2009 topics set
Structure of human DNA polymerase kappa inserting dATP opposite an 8-OxoG DNA lesion. Rodrigo Vasquez-Del Carpio, Timothy D Silverstein, Samer Lone, Michael K Swan, Jayati Roy Choudhury, Robert E Johnson, Satya Prakash, Louise Prakash, Aneel K Aggarwal PloS one 2009 topics set
Effect of N-2-acetylaminofluorene and 2-aminofluorene adducts on DNA binding and synthesis by yeast DNA polymerase eta. Venkataramana Vooradi, Louis J Romano Biochemistry 2009 new
Cervical cancer isolate PT3, super-permissive for adeno-associated virus replication, over-expresses DNA polymerase delta, PCNA, RFC and RPA. Bum Yong Kang, Hong You, Sarmistha Bandyopadhyay, Nalini Agrawal, Russell B Melchert, Alexei G Basnakian, Yong Liu, Paul L Hermonat BMC Microbiol 2009 new
Sulfanyltriazole/tetrazoles: a promising class of HIV-1 NNRTIs. Peng Zhan, Zhongjie Li, Xinyong Liu, Erik De Clercq Mini reviews in medicinal chemistry 2009 pols set
An 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase lambda. Barbara van Loon, Ulrich Hübscher Proceedings of the National Academy of Sciences of the United States of America 2009 pols set
The 3'-5' proofreading exonuclease of archaeal family-B DNA polymerase hinders the copying of template strand deaminated bases. Henry J Russell, Tomas T Richardson, Kieran Emptage, Bernard A Connolly Nucleic acids research 2009 partial results
The mechanism of ATP-dependent primer-template recognition by a clamp loader complex. Kyle R Simonetta, Steven L Kazmirski, Eric R Goedken, Aaron J Cantor, Brian A Kelch, Randall McNally, Steven N Seyedin, Debora L Makino, Mike E O'Donnell, John Kuriyan Cell 2009 topics set
Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm. Takuji Oyama, Hayato Oka, Kouta Mayanagi, Tsuyoshi Shirai, Kyoko Matoba, Ryosuke Fujikane, Yoshizumi Ishino, Kosuke Morikawa BMC structural biology 2009 pols set
Crystallographic study of a novel subnanomolar inhibitor provides insight on the binding interactions of alkenyldiarylmethanes with human immunodeficiency virus-1 reverse transcriptase. Matthew D Cullen, William C Ho, Joseph David Bauman, Kalyan Das, Edward Arnold, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman J Med Chem 2009 partial results
GS-9191 is a novel topical prodrug of the nucleotide analog 9-(2-phosphonylmethoxyethyl)guanine with antiproliferative activity and possible utility in the treatment of human papillomavirus lesions. Grushenka H I Wolfgang, Riri Shibata, Jianying Wang, Adrian S Ray, Sylvia Wu, Edward Doerrfler, Hans Reiser, William A Lee, Gabriel Birkus, Neil D Christensen, Graciela Andrei, Robert Snoeck Antimicrobial agents and chemotherapy 2009 new
A new drug combination therapy for treatment-naive patients with HIV-1 infection, consisting of raltegravir, emtricitabine and tenofovir disoproxil fumarate. Erik De Clercq Expert opinion on pharmacotherapy 2009 pols set
The mechanistic architecture of thermostable Pyrococcus furiosus family B DNA polymerase motif A and its interaction with the dNTP substrate. Edward M Kennedy, Christopher Hergott, Stephen Dewhurst, Baek Kim Biochemistry 2009 new
Competitive capacity of HIV-1 strains carrying M184I or Y181I drug-resistant mutations. Jinming Li, Lin Li, Han-Ping Li, Dao-Min Zhuang, Si-Yang Liu, Yong-Jian Liu, Zuo-Yi Bao, Zhengqiang Wang, Jing-Yun Li Chinese medical journal 2009 new
The block of DNA polymerase delta strand displacement activity by an abasic site can be rescued by the concerted action of DNA polymerase beta and Flap endonuclease 1. Giovanni Maga, Barbara van Loon, Emmanuele Crespan, Giuseppe Villani, Ulrich Hübscher The Journal of biological chemistry 2009 new
Coronary microvascular resistance: methods for its quantification in humans. Paul Knaapen, Paolo G Camici, Koen M Marques, Robin Nijveldt, Jeroen J Bax, Nico Westerhof, Marco J W Götte, Michael Jerosch-Herold, Heinrich R Schelbert, Adriaan A Lammertsma, Albert C van Rossum Basic Res Cardiol 2009 new
Strand displacement by DNA polymerase III occurs through a tau-psi-chi link to single-stranded DNA-binding protein coating the lagging strand template. Quan Yuan, Charles S McHenry The Journal of biological chemistry 2009 new
The roles of APE1, APE2, DNA polymerase beta and mismatch repair in creating S region DNA breaks during antibody class switch. Carol E Schrader, Jeroen E J Guikema, Xiaoming Wu, Janet Stavnezer Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2009 new
HIV-1 reverse transcriptase can simultaneously engage its DNA/RNA substrate at both DNA polymerase and RNase H active sites: implications for RNase H inhibition. Greg L Beilhartz, Michaela Wendeler, Noel S Baichoo, Jason W Rausch, Stuart F J Le Grice, Matthias Götte Journal of molecular biology 2009 complete Bruno Marchand
Single-molecule measurements of synthesis by DNA polymerase with base-pair resolution. Thomas David Christian, Louis J Romano, David Rueda Proceedings of the National Academy of Sciences of the United States of America 2009 new
Functional importance of bacteriophage phi29 DNA polymerase residue Tyr148 in primer-terminus stabilisation at the 3'-5' exonuclease active site. Patricia Pérez-Arnaiz, José María Lázaro, Margarita Salas, Miguel de Vega Journal of molecular biology 2009 partial results
A trimeric DNA polymerase complex increases the native replication processivity. Andrey L Mikheikin, Hsiang-Kai Lin, Preeti Mehta, Linda Jen-Jacobson, Michael A Trakselis Nucleic acids research 2009 partial results
Influence of local sequence context on damaged base conformation in human DNA polymerase iota: molecular dynamics studies of nucleotide incorporation opposite a benzo[a]pyrene-derived adenine lesion. Kerry Donny-Clark, Suse Broyde Nucleic acids research 2009 pols set
Anti-HIV drugs: 25 compounds approved within 25 years after the discovery of HIV. Erik De Clercq International journal of antimicrobial agents 2009 pols set
1,2,3-Selenadiazole thioacetanilides: synthesis and anti-HIV activity evaluation. Peng Zhan, Xinyong Liu, Zengjun Fang, Christophe Pannecouque, Erik De Clercq Bioorganic & medicinal chemistry 2009 pols set
Regulation of DNA polymerase beta by the LMP1 oncoprotein of EBV through the nuclear factor-kappaB pathway. Nathalie Faumont, Christophe Le Clorennec, Pierre Teira, Gauthier Goormachtigh, Jean Coll, Yvan Canitrot, Christophe Cazaux, Jean-Sébastien Hoffmann, Pierre Brousset, Georges Delsol, Jean Feuillard, Fabienne Meggetto Cancer research 2009 new
Replication stress activates DNA polymerase alpha-associated Chk1. Lorena Taricani, Frances Shanahan, David Parry Cell Cycle 2009 new
Design strategies of novel NNRTIs to overcome drug resistance. Peng Zhan, Xinyong Liu, Zhongjie Li, Christophe Pannecouque, Erik De Clercq Current medicinal chemistry 2009 pols set
Physical interactions between Mcm10, DNA, and DNA polymerase alpha. Eric M Warren, Hao Huang, Ellen Fanning, Walter J Chazin, Brandt F Eichman The Journal of biological chemistry 2009 complete Brandt F Eichman*
Synthesis and anti-HIV activity evaluation of 2-(4-(naphthalen-2-yl)-1,2,3-thiadiazol-5-ylthio)-N-acetamides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. Peng Zhan, Xinyong Liu, Zengjun Fang, Zhongjie Li, Christophe Pannecouque, Erik De Clercq European journal of medicinal chemistry 2009 pols set
Drug targets in cytomegalovirus infection. Graciella Andrei, Erik De Clercq, Robert Snoeck Infectious disorders drug targets 2009 new
Highly efficient incorporation of the fluorescent nucleotide analogs tC and tCO by Klenow fragment. Peter Sandin, Gudrun Stengel, Thomas Ljungdahl, Karl Börjesson, Bertil Macao, L Marcus Wilhelmsson Nucleic acids research 2009 partial results
Kinetics of deoxy-CTP incorporation opposite a dG-C8-N-2-aminofluorene adduct by a high-fidelity DNA polymerase. Dominique Y Burnouf, Jérôme E Wagner Journal of molecular biology 2009 new
Transcription and reverse transcription of artificial nucleic acids involving backbone modification by template-directed DNA polymerase reactions. Masayasu Kuwahara, Hidetoshi Takeshima, Jun-ichi Nagashima, Satoshi Minezaki, Hiroaki Ozaki, Hiroaki Sawai Bioorg Med Chem 2009 new
The crystal structure of PF-8, the DNA polymerase accessory subunit from Kaposi's sarcoma-associated herpesvirus. Jennifer L Baltz, David J Filman, Mihai Ciustea, Janice Elaine Y Silverman, Catherine L Lautenschlager, Donald M Coen, Robert P Ricciardi, James M Hogle J Virol 2009 new
Functional analysis of mutant mitochondrial DNA polymerase proteins involved in human disease. Sherine S L Chan, William C Copeland Methods in molecular biology (Clifton, N.J.) 2009 new
The active form of DNA polymerase V is UmuD'(2)C-RecA-ATP. Qingfei Jiang, Kiyonobu Karata, Roger Woodgate, Michael M Cox, Myron F Goodman Nature 2009 pols set
Structure-function relationships in miscoding by Sulfolobus solfataricus DNA polymerase Dpo4: guanine N2,N2-dimethyl substitution produces inactive and miscoding polymerase complexes. Haijiang Zhang, Robert Lawton Eoff, Ivan D Kozekov, Carmelo J Rizzo, Martin Egli, F Peter Guengerich The Journal of biological chemistry 2009 topics set
Selective recognition of unnatural imidazopyridopyrimidine:naphthyridine base pairs consisting of four hydrogen bonds by the Klenow fragment. Noriaki Minakawa, Shintaro Ogata, Mayumi Takahashi, Akira Matsuda Journal of the American Chemical Society 2009 topics set
3-O-methylfunicone, a selective inhibitor of mammalian Y-family DNA polymerases from an Australian sea salt fungal strain. Yoshiyuki Mizushina, Hirohisa Motoshima, Yasuhiro Yamaguchi, Toshifumi Takeuchi, Ken Hirano, Fumio Sugawara, Hiromi Yoshida Marine drugs 2009 pols set
Evolution of DNA polymerases: an inactivated polymerase-exonuclease module in Pol epsilon and a chimeric origin of eukaryotic polymerases from two classes of archaeal ancestors. Tahir H Tahirov, Kira S Makarova, Igor B Rogozin, Youri I Pavlov, Eugene V Koonin Biol Direct 2009 partial results
Steric and electrostatic effects at the C2 atom substituent influence replication and miscoding of the DNA deamination product deoxyxanthosine and analogs by DNA polymerases. Huidong Zhang, Urban Bren, Ivan D Kozekov, Carmelo J Rizzo, Donald F Stec, F Peter Guengerich Journal of molecular biology 2009 pols set
DNA polymerase epsilon, acetylases and remodellers cooperate to form a specialized chromatin structure at a tRNA insulator. Namrita Dhillon, Jesse Raab, Julie Guzzo, Shawn J Szyjka, Sunil Gangadharan, Oscar M Aparicio, Brenda Andrews, Rohinton T Kamakaka The EMBO journal 2009 new
A possible mechanism for the dynamics of transition between polymerase and exonuclease sites in a high-fidelity DNA polymerase. Ping Xie J Theor Biol 2009 complete Ping Xie*
Non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 13: synthesis of fluorine-containing diaryltriazine derivatives for in vitro anti-HIV evaluation against wild-type strain. Yuan-Zhen Xiong, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque Chemistry & biodiversity 2009 pols set
A role for DNA polymerase mu in the emerging DJH rearrangements of the postgastrulation mouse embryo. Beatriz Gozalbo-López, Paula Andrade, Gloria Terrados, Belén de Andrés, Natalia Serrano, Isabel Cortegano, Beatriz Palacios, Antonio Bernad, Luis Blanco, Miguel A R Marcos, María Luisa Gaspar Molecular and cellular biology 2009 new
A passion for research. Margarita Salas Cellular and molecular life sciences : CMLS 2009 new
An in trans interaction at the interface of the helicase and primase domains of the hexameric gene 4 protein of bacteriophage T7 modulates their activities. B Zhu, Seung-Joo Lee, Charles C Richardson The Journal of biological chemistry 2009 new
DNA polymerase beta substrate specificity: side chain modulation of the "A-rule". William A Beard, David D Shock, Vinod K Batra, Lars C Pedersen, Samuel H Wilson The Journal of biological chemistry 2009 topics set
Accommodation of an N-(deoxyguanosin-8-yl)-2-acetylaminofluorene adduct in the active site of human DNA polymerase iota: Hoogsteen or Watson-Crick base pairing? Kerry Donny-Clark, Robert Shapiro, Suse Broyde Biochemistry 2009 pols set
Mechanisms associated with HIV-1 resistance to acyclovir by the V75I mutation in reverse transcriptase. Egor P Tchesnokov, Aleksandr Obikhod, Ivana Massud, Andrea Lisco, Christophe Vanpouille, Beda Brichacek, Jan Balzarini, Christopher McGuigan, Marco Derudas, Leonid Margolis, Raymond F Schinazi, Matthias Götte The Journal of biological chemistry 2009 topics set
Differential roles for membrane-bound and soluble syndecan-1 (CD138) in breast cancer progression. Viktoriya Nikolova, Chuay-Yeng Koo, Sherif Abdelaziz Ibrahim, Zhengqiang Wang, Dorothe Spillmann, Rita Dreier, Reinhard Kelsch, Jeanett Fischgräbe, Martin Smollich, Laura H Rossi, Walter Sibrowski, Pia Wülfing, Ludwig Kiesel, George W Yip, Matthias Götte Carcinogenesis 2009 new
The flexible loop of the human cytomegalovirus DNA polymerase processivity factor ppUL44 is required for efficient DNA binding and replication in cells. Gualtiero Alvisi, Daniela Martino Roth, Daria Camozzi, Gregory S Pari, Arianna Loregian, Alessandro Ripalti, David A Jans J Virol 2009 pols set
Antitumor effects of targeting hTERT lentivirus-mediated RNA interference against KB cell lines. Dan Chen, Hongzhang Huang, Chaobin Pan, Jianguang Wang, Bin Zhang, Anxun Wang Oncology research 2009 new
Impact of novel human immunodeficiency virus type 1 reverse transcriptase mutations P119S and T165A on 4'-ethynylthymidine analog resistance profile. Guangwei Yang, Elijah Paintsil, Ginger E Dutschman, Susan P Grill, Chuan-Jen Wang, Jianhong Wang, Hiromichi Tanaka, Takayuki Hamasaki, Masanori Baba, Yung-Chi Cheng Antimicrobial agents and chemotherapy 2009 new
Synthesis and studies of new 2-(coumarin-4-yloxy)-4,6-(substituted)-S-triazine derivatives as potential anti-HIV agents. Dharmesh H Mahajan, Christophe Pannecouque, Erik De Clercq, Kishor H Chikhalia Archiv der Pharmazie 2009 pols set
Cloning and characterization of a DNA polymerase beta gene from Trypanosoma cruzi. Juan A Venegas, Lena Aslund, Aldo Solari Parasitol Int 2009 topics set
Characterization of DNA polymerase from the hyperthermophilic archaeon Thermococcus marinus and its application to PCR. Heejin Bae, Kee Pum Kim, Jong Il Lee, Jae-Geun Song, Eui-Joon Kil, Joong Su Kim, Suk-Tae Kwon Extremophiles 2009 new
Effects of ectopic expression of human telomerase reverse transcriptase on immortalization of feather keratinocyte stem cells. Yulin Xu, Minli Yu, Fabai Wu, Jianguo Sun, Chris Wood, Masa-Aki Hattori, Jinfu Wang, Yongmei Xi Journal of experimental zoology. Part B, Molecular and developmental evolution 2009 new
Role of the heparan sulfate proteoglycan syndecan-1 (CD138) in delayed-type hypersensitivity. Behzad Kharabi Masouleh, Gerdy B Ten Dam, Martin K Wild, Ruth Seelige, Johan van der Vlag, Angelique L Rops, Frank G Echtermeyer, Dietmar Vestweber, Toin H van Kuppevelt, Ludwig Kiesel, Matthias Götte J Immunol 2009 new
Molecular analyses of a three-subunit euryarchaeal clamp loader complex from Methanosarcina acetivorans. Yi-Hsing Chen, Yuyen Lin, Aya Yoshinaga, Benazir Chhotani, Jenna L Lorenzini, Alexander A Crofts, Shou Mei, Roderick I Mackie, Yoshizumi Ishino, Isaac K O Cann Journal of bacteriology 2009 new
Design, synthesis, and SAR of naphthyl-substituted Diarylpyrimidines as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Yong-Hong Liang, Xiao-Qing Feng, Zhao-Sen Zeng, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq ChemMedChem 2009 pols set
The polymerase eta translesion synthesis DNA polymerase acts independently of the mismatch repair system to limit mutagenesis caused by 7,8-dihydro-8-oxoguanine in yeast. Sarah V Mudrak, Caroline Welz-Voegele, Sue Jinks-Robertson Molecular and cellular biology 2009 new
Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta. Michael K Swan, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Nature structural & molecular biology 2009 topics set
Proteolysis of the proofreading subunit controls the assembly of Escherichia coli DNA polymerase III catalytic core. Daniela Bressanin, Alessandra Stefan, Fabrizio Dal Piaz, Stefano Cianchetta, Luca Reggiani, Alejandro Hochkoeppler Biochimica et biophysica acta 2009 complete Alejandro Hochkoeppler*
Mutants of Taq DNA polymerase resistant to PCR inhibitors allow DNA amplification from whole blood and crude soil samples. Milko B Kermekchiev, Lyubka I Kirilova, Erika E Vail, Wayne M Barnes Nucleic acids research 2009 pols set
AML1-ETO9a is correlated with C-KIT overexpression/mutations and indicates poor disease outcome in t(8;21) acute myeloid leukemia-M2. B Jiao, C-F Wu, Y Liang, H-M Chen, S-M Xiong, B Chen, J-Y Shi, Y-Y Wang, Jing-Houng Wang, Y Chen, J-M Li, L-J Gu, J-Y Tang, Z-X Shen, B-W Gu, W-L Zhao, Zhiwen Chen, S-J Chen Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2009 new
PCNA is required for initiation of recombination-associated DNA synthesis by DNA polymerase delta. Xincang Li, Carrie M W Stith, Peter M J Burgers, Wolf-Dietrich Heyer Molecular cell 2009 new
The inhibitory action of kohamaic acid A derivatives on mammalian DNA polymerase beta. Yoshiyuki Mizushina, Daisuke Manita, Toshifumi Takeuchi, Fumio Sugawara, Yuko Kumamoto-Yonezawa, Yuki Matsui, Masaharu Takemura, Mitsuru Sasaki, Hiromi Yoshida, Hirosato Takikawa Molecules 2009 pols set
Structural and functional analysis of Sulfolobus solfataricus Y-family DNA polymerase Dpo4-catalyzed bypass of the malondialdehyde-deoxyguanosine adduct. Robert Lawton Eoff, Jennifer B Stafford, Jozsef Szekely, Carmelo J Rizzo, Martin Egli, F Peter Guengerich, Lawrence J Marnett Biochemistry 2009 topics set
Polymerase-tailored variations in the water-mediated and substrate-assisted mechanism for nucleotidyl transfer: insights from a study of T7 DNA polymerase. Liming Wang, Suse Broyde, Yongqing Zhang Journal of molecular biology 2009 pols set
Characterization of DNA polymerase beta splicing variants in gastric cancer: the most frequent exon 2-deleted isoform is a non-coding RNA. Valeria Simonelli, Mariarosaria D'Errico, Domenico Palli, Rajendra Prasad, Samuel H Wilson, Eugenia Dogliotti Mutation research 2009 new
Bypass specialists operate together. Kei-ichi Takata, RichardD Wood The EMBO journal 2009 topics set
DNA polymerase beta reveals enhanced activity and processivity in reverse micelles. Rashid O Anarbaev, Anastasia L Rogozina, Olga I Lavrik Biophys Chem 2009 pols set
Translesional DNA synthesis through a C8-guanyl adduct of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in Vitro: REV1 inserts dC opposite the lesion, and DNA polymerase kappa potentially catalyzes extension reaction from the 3'-dC terminus. Hirokazu Fukuda, Takeji Takamura-Enya, Yuji Masuda, Takehiko Nohmi, Chiho Seki, Kenji Kamiya, Takashi Sugimura, Chikahide Masutani, Fumio Hanaoka, Hitoshi Nakagama The Journal of biological chemistry 2009 new
Initiation of new DNA strands by the herpes simplex virus-1 primase-helicase complex and either herpes DNA polymerase or human DNA polymerase alpha. Nisha A Cavanaugh, Robert D Kuchta The Journal of biological chemistry 2009 new
Functional mapping of the fission yeast DNA polymerase delta B-subunit Cdc1 by site-directed and random pentapeptide insertion mutagenesis. Javier Sanchez Garcia, Andrey G Baranovskiy, Elena V Knatko, Fiona C Gray, Tahir H Tahirov, Stuart A MacNeill BMC Mol Biol 2009 new
Finger domain mutation affects enzyme activity, DNA replication efficiency, and fidelity of an exonuclease-deficient DNA polymerase of herpes simplex virus type 1. Wang Tian, Ying T Hwang, Qiangsheng Lu, Charles B C Hwang J Virol 2009 partial results
TopBP1 and DNA polymerase-alpha directly recruit the 9-1-1 complex to stalled DNA replication forks. Shan Yan, W Matthew Michael J Cell Biol 2009 topics set
RNase H active site inhibitors of human immunodeficiency virus type 1 reverse transcriptase: design, biochemical activity, and structural information. Thorsten A Kirschberg, Mini Balakrishnan, Neil H Squires, Tiffany Barnes, Katherine M Brendza, Xiaowu Chen, Eugene J Eisenberg, Weili Jin, Nilima Kutty, Stephanie Leavitt, Albert C Liclican, Qi Liu, Xiaohong Liu, John Mak, Jason K Perry, Michael Wang, William J Watkins, Eric B Lansdon J Med Chem 2009 new
Pif1 helicase lengthens some Okazaki fragment flaps necessitating Dna2 nuclease/helicase action in the two-nuclease processing pathway. JasonE Pike, PeterMJ Burgers, JudithL Campbell, RobertA Bambara The Journal of biological chemistry 2009 new
Substitution of Ile(707) for Leu in Klentaq DNA polymerase reduces the amplification capacity of the enzyme. K Davalieva, D G Efremov Prilozi 2009 new
[Expression study of DNA translesion synthesis genes in human primary glioma]. Cai-hua Xi, Jin Hu, Hui-bo Wang, Shu-yu Zhang, Da-lu Ru Zhonghua yi xue za zhi 2009 topics set
Characterization of the effects of cisplatin and carboplatin on cell cycle progression and DNA damage response activation in DNA polymerase eta-deficient human cells. Séverine Cruet-Hennequart, Sangamitra Villalan, Agnieszka Kaczmarczyk, Elaine O'Meara, Anna M Sokol, Michael P Carty Cell Cycle 2009 new
Mice expressing an error-prone DNA polymerase in mitochondria display elevated replication pausing and chromosomal breakage at fragile sites of mitochondrial DNA. Laura J Bailey, Tricia J Cluett, Aurelio Reyes, Tom A Prolla, Joanna Poulton, Christiaan Leeuwenburgh, Ian J Holt Nucleic acids research 2009 new
Role of TLS DNA polymerases eta and kappa in processing naturally occurring structured DNA in human cells. Rémy Bétous, Laurie Rey, Guliang Wang, Marie-Jeanne Pillaire, Nadine Puget, Janick Selves, Denis S F Biard, Kazuo Shin-ya, Karen M Vasquez, Christophe Cazaux, Jean-Sébastien Hoffmann Molecular carcinogenesis 2009 pols set
Characterization of a natural mutator variant of human DNA polymerase lambda which promotes chromosomal instability by compromising NHEJ. Gloria Terrados, Jean-Pascal Capp, Yvan Canitrot, Miguel García-Díaz, Katarzyna Bebenek, Tomas Kirchhoff, Alberto Villanueva, François Boudsocq, Valérie Bergoglio, Christophe Cazaux, Thomas A Kunkel, Jean-Sébastien Hoffmann, Luis Blanco PloS one 2009 pols set
[Construction and immunoscreening of cDNA library of Babesia orientalis]. Qin Liu, Dan-Na Zhou, Yan-Qin Zhou, Yongqing Zhang, Lan He, Bao-An Yao, Jun-Long Zhao Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 2009 new
Disruption of mitochondrial DNA replication in Drosophila increases mitochondrial fast axonal transport in vivo. Rehan M Baqri, Brittany A Turner, Mary B Rheuben, Bradley D Hammond, Laurie S Kaguni, Kyle E Miller PloS one 2009 complete Rehan M Baqri*
Gastrointestinal hyperplasia with altered expression of DNA polymerase beta. Katsuhiko Yoshizawa, Elena Jelezcova, Ashley R Brown, Julie F Foley, Abraham Nyska, Xiangli Cui, Lorne J Hofseth, Robert M Maronpot, Samuel H Wilson, Antonia R Sepulveda, Robert W Sobol PloS one 2009 new
Biochemical properties and base excision repair complex formation of apurinic/apyrimidinic endonuclease from Pyrococcus furiosus. Shinichi Kiyonari, Saki Tahara, Tsuyoshi Shirai, Shigenori Iwai, Sonoko Ishino, Yoshizumi Ishino Nucleic acids research 2009 new
Lack of DNA polymerase theta (POLQ) radiosensitizes bone marrow stromal cells in vitro and increases reticulocyte micronuclei after total-body irradiation. Julie P Goff, Donna S Shields, Masayuki Seki, Serah Choi, Michael W Epperly, Tracy Dixon, Hong Wang, Christopher J Bakkenist, Stephen D Dertinger, Dorothea K Torous, John P Wittschieben, Richard D Wood, Joel S Greenberger Radiat Res 2009 new
Dyslipidaemia and Intima-Media Thickness of Carotid Arteries in Thirty-Five HIV/AIDS Patients Receiving Highly Active Antiretroviral Therapy. Xuexiang Zhang, Xueyan Jiang, Hongzhou Lu, Fang Shen, Jiangrong Wang International journal of biomedical science : IJBS 2009 topics set
Role of Escherichia coli DNA polymerase I in chromosomal DNA replication fidelity. Karolina Makiela-Dzbenska, Malgorzata Jaszczur, Magdalena Banach-Orlowska, Piotr Jonczyk, Roel M Schaaper, I Fijalkowska Molecular microbiology 2009 pols set
Signature nucleotide polymorphisms at positions 64 and 65 in reverse transcriptase favor the selection of the K65R resistance mutation in HIV-1 subtype C. Cédric F Invernizzi, Dimitrios Coutsinos, Maureen Oliveira, Daniela D Moisi, Bluma G Brenner, Mark A. Wainberg The Journal of infectious diseases 2009 pols set
Reducing the impact of PCR-mediated recombination in molecular evolution and environmental studies using a new-generation high-fidelity DNA polymerase. Daniel J G Lahr, Laura A Katz BioTechniques 2009 new
Binding to PCNA in Euryarchaeal DNA Replication requires two PIP motifs for DNA polymerase D and one PIP motif for DNA polymerase B. Benoît Castrec, Christophe Rouillon, Ghislaine Henneke, Didier Flament, Joël Querellou, Jean-Paul Raffin Journal of molecular biology 2009 new
Myocardial bridging in aborted sudden death: just an innocent bystander? Paul Knaapen, Marco J W Götte, Carel C de Cock N Z Med J 2009 new
Mutations in the thumb allow human immunodeficiency virus type 1 reverse transcriptase to be cleaved by protease in virions. Linda L Dunn, Mary Jane McWilliams, Kalyan Das, Edward Arnold, Stephen H Hughes Journal of virology 2009 pols set
The use of 2-aminopurine fluorescence to study DNA polymerase function. Linda J Reha-Krantz Methods in molecular biology (Clifton, N.J.) 2009 complete
Conformational landscape of the human immunodeficiency virus type 1 reverse transcriptase non-nucleoside inhibitor binding pocket: lessons for inhibitor design from a cluster analysis of many crystal structures. Kristina A Paris, Omar Haq, Anthony K Felts, Kalyan Das, Edward Arnold, Ronald M Levy Journal of medicinal chemistry 2009 pols set
Structural basis for the role of the K65R mutation in HIV-1 reverse transcriptase polymerization, excision antagonism, and tenofovir resistance. Kalyan Das, Rajiv P Bandwar, Kirsten L White, Joy Y Feng, Stefan G Sarafianos, Steven Tuske, Xiongying Tu, Arthur D Clark, Paul L Boyer, Xiaorong Hou, Barbara L Gaffney, Roger A Jones, Michael D Miller, Stephen H Hughes, Edward Arnold The Journal of biological chemistry 2009 partial results
DinB upregulation is the sole role of the SOS response in stress-induced mutagenesis in Escherichia coli. Rodrigo S Galhardo, Robert Do, Masami Yamada, Errol C Friedberg, P J Hastings, Takehiko Nohmi, Susan M Rosenberg Genetics 2009 topics set
DNA polymerase switching: effects on spontaneous mutagenesis in Escherichia coli. Elena Curti, John P McDonald, Samantha Mead, Roger Woodgate Molecular microbiology 2009 new
The accessory subunit of mitochondrial DNA polymerase gamma determines the DNA content of mitochondrial nucleoids in human cultured cells. M Di Re, H Sembongi, J He, Aurelio Reyes, T Yasukawa, P Martinsson, Laura J Bailey, Steffi Goffart, J D Boyd-Kirkup, T S Wong, A R Fersht, Johannes N Spelbrink, Ian J Holt Nucleic acids research 2009 new
Base excision repair in early zebrafish development: evidence for DNA polymerase switching and standby AP endonuclease activity. Sean Fortier, Xiaojie Yang, Yazhen Wang, Richard A O Bennett, Phyllis R Strauss Biochemistry 2009 topics set
Frameshift deletion by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W is selective for purines and involves normal conformational change followed by slow phosphodiester bond formation. Haijiang Zhang, Jeff W Beckman, F Peter Guengerich The Journal of biological chemistry 2009 pols set
A useful strategy to construct DNA polymerases with different properties by using genetic resources from environmental DNA. Hiroaki Matsukawa, Takeshi Yamagami, Yutaka Kawarabayasi, Yukiko Miyashita, Masaaki Takahashi, Yoshizumi Ishino Genes & genetic systems 2009 new
PCNA monoubiquitylation and DNA polymerase eta ubiquitin-binding domain are required to prevent 8-oxoguanine-induced mutagenesis in Saccharomyces cerevisiae. Patricia Auffret van der Kemp, Marcelo de Padula, Guenaelle Burguiere-Slezak, Helle D Ulrich, Serge Boiteux Nucleic acids research 2009 new
Translesion synthesis of abasic sites by yeast DNA polymerase epsilon. Nasim Sabouri, Erik Johansson The Journal of biological chemistry 2009 new
Synthesis of alkenyldiarylmethanes (ADAMs) containing benzo[d]isoxazole and oxazolidin-2-one rings, a new series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors. Bo-Liang Deng, Yaofeng Zhao, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman European journal of medicinal chemistry 2009 pols set
Population-specific variation in haplotype composition and heterozygosity at the POLB locus. Jennifer Yamtich, William C Speed, Eva Straka, Judith R Kidd, Joann B Sweasy, Kenneth K Kidd DNA repair 2009 new
PCNA mono-ubiquitination and activation of translesion DNA polymerases by DNA polymerase {alpha}. Motoshi Suzuki, Atsuko Niimi, Siripan Limsirichaikul, Shuta Tomida, Qin Miao Huang, Shunji Izuta, Jiro Usukura, Yasutomo Itoh, Takashi Hishida, Tomohiro Akashi, Yoshiyuki Nakagawa, Akihiko Kikuchi, Youri I Pavlov, Takashi Murate, Tomonori Takahashi J Biochem 2009 new
Incorporation of an inducible nucleotide analog into DNA by DNA polymerases. Md Monsur Ali, Shuhei Imoto, Yingqian Li, Shigeki Sasaki, Fumi Nagatsugi Bioorg Med Chem 2009 topics set
Effect of the human immunodeficiency virus type 1 reverse transcriptase polymorphism Leu-214 on replication capacity and drug susceptibility. MC Puertas, MJ Buzón, A Artese, S Alcaro, L Menéndez-Arias, CF Perno, B Clotet, F Ceccherini-Silberstein, J Martinez-Picado Journal of virology 2009 topics set
Characterization and PCR optimization of the thermostable family B DNA polymerase from Thermococcus guaymasensis Suk-Tae Kwon, Hyekyung Shim, Jin Choia Jeong, Jae Kima Yun, Jae-Geun Songa, Eui-Joon Kila, Il Lee Jong Enzyme and microbial technology 2009 partial results
Inhibition of human DNA polymerase beta activity by the anticancer prodrug Cloretazine. Abbie M Frederick, Marguerite L Davis, Kevin P Rice Biochem Biophys Res Commun 2009 pols set
Aberrant DNA polymerase alpha is excluded from the nucleus by defective import and degradation in the nucleus. Christian S Eichinger, Takeshi Mizuno, Keiko Mizuno, Yasuyuki Miyake, Ken-ichiro Yanagi, Naoko Imamoto, Fumio Hanaoka The Journal of biological chemistry 2009 complete Takeshi Mizuno*
Prevalence of the K65R resistance reverse transcriptase mutation in different HIV-1 subtypes in Israel. Dan Turner, Eduardo Shahar, Eugene Katchman, Eynat Kedem, Natasha Matus, Michal Katzir, Gamal Hassoun, Shimon Pollack, Rivka Kessner, Mark A. Wainberg, Boaz Avidor Journal of medical virology 2009 pols set
Evidence for the involvement of human DNA polymerase N in the repair of DNA interstrand cross-links. Laura Zietlow, Leigh Anne Smith, Mika Bessho, Tadayoshi Bessho Biochemistry 2009 complete Tadayoshi Bessho*
Yeast Rev1 protein promotes complex formation of DNA polymerase zeta with Pol32 subunit of DNA polymerase delta. Narottam Acharya, Robert E Johnson, Vincent Pagès, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2009 new
[Different instability of microsatellite CAG repeat in two groups of haplotypes of the human mitochondrial gamma-DNA-polymerase gene]. B A Maliarchuk, M A Perkova, Miroslava V Derenko Mol Biol (Mosk) 2009 new
Involvement of the beta clamp in methyl-directed mismatch repair in vitro. Anna Pluciennik, Vickers Burdett, Olga Lukianova, Mike E O'Donnell, Paul Modrich The Journal of biological chemistry 2009 topics set
Mechanistic studies of the bypass of a bulky single-base lesion catalyzed by a Y-family DNA polymerase. Shanen M Sherrer, Jessica A Brown, Lindsey R Pack, Vijay P Jasti, Jason D Fowler, Ashis K Basu, Zucai Suo The Journal of biological chemistry 2009 topics set
Mechanism of polymerase collision release from sliding clamps on the lagging strand. Roxana E Georgescu, Isabel Kurth, Nina Y Yao, Jelena Stewart, Olga Yurieva, Mike E O'Donnell The EMBO journal 2009 topics set
Transplantation of BMSCs expressing hPDGF-A/hBD2 promotes wound healing in rats with combined radiation-wound injury. L Hao, Jiqun Wang, Z Zou, G Yan, S Dong, J Deng, X Ran, Y Feng, Chen Luo, Yujue Wang, T Cheng Gene therapy 2009 new
Clinical relevance of substitutions in the connection subdomain and RNase H domain of HIV-1 reverse transcriptase from a cohort of antiretroviral treatment-naïve patients. Atsuko Hachiya, Kazuki Shimane, Stefan G Sarafianos, Eiichi N Kodama, Yasuko Sakagami, Fujie Negishi, Hirokazu Koizumi, Hiroyuki Gatanaga, Masao Matsuoka, Masafumi Takiguchi, Shinichi Oka Antiviral research 2009 pols set
Ubiquitin-binding motif of human DNA polymerase eta is required for correct localization. Simone Sabbioneda, Catherine M Green, Marzena Bienko, Patricia L Kannouche, Ivan Dikic, Alan R Lehmann Proceedings of the National Academy of Sciences of the United States of America 2009 complete Alan R Lehmann*
Versatility of Y-family Sulfolobus solfataricus DNA polymerase Dpo4 in translesion synthesis past bulky N2-alkylguanine adducts. Haijiang Zhang, Robert Lawton Eoff, Ivan D Kozekov, Carmelo J Rizzo, Martin Egli, F Peter Guengerich The Journal of biological chemistry 2009 topics set
Expression of an X-family DNA polymerase, pol lambda, in the respiratory epithelium of non-small cell lung cancer patients with habitual smoking. Taro Ohba, Takurou Kometani, Fumihiro Shoji, Tokujiro Yano, Ichiro Yoshino, Yoshino Ichiro, Kenichi Taguchi, Isao Kuraoka, Shinya Oda, Yoshihiko Maehara Mutation research 2009 new
A real-time fluorescence method for enzymatic characterization of specialized human DNA polymerases. Dorjbal Dorjsuren, David M Wilson, William A Beard, John P McDonald, Christopher P Austin, Roger Woodgate, Samuel H Wilson, Anton Simeonov Nucleic acids research 2009 pols set
Discrimination between right and wrong purine dNTPs by DNA polymerase I from Bacillus stearothermophilus. Michael Trostler, Alison Delier, Jeff W Beckman, Milan Urban, Jennifer N Patro, Thomas E Spratt, Lorena S Beese, Robert D Kuchta Biochemistry 2009 topics set
A computational study of the hydrolysis of dGTP analogues with halomethylene-modified leaving groups in solution: implications for the mechanism of DNA polymerases. Shina C L Kamerlin, Charles E McKenna, Myron F Goodman, Myron F Goondman, Arieh Warshel Biochemistry 2009 new
Involvement of the TPR2 subdomain movement in the activities of phi29 DNA polymerase. Irene Rodríguez, José María Lázaro, Margarita Salas, Miguel de Vega Nucleic acids research 2009 topics set
Polymerase dynamics at the eukaryotic DNA replication fork. Peter M J Burgers The Journal of biological chemistry 2009 new
Plasmid-based lacZalpha assay for DNA polymerase fidelity: application to archaeal family-B DNA polymerase. Stanislaw K Jozwiakowski, Bernard A Connolly Nucleic acids research 2009 topics set
Non-nucleoside reverse transcriptase inhibitors (Part 18): synthesis and anti-HIV activity of 4-allylamino or 4-azido substituted diaryltriazines. Yuan-Zhen Xiong, Hai-Rong Hu, Fen-Er Chen, Jan Balzarini, Christophe Pannecouque, Erik De Clercq Yao xue xue bao = Acta pharmaceutica Sinica 2009 new
Specific nucleotide binding and rebinding to individual DNA polymerase complexes captured on a nanopore. Nicholas Hurt, Hongyun Wang, Mark Akeson, Kate R Lieberman Journal of the American Chemical Society 2009 complete Kate R Lieberman*
A light-activated DNA polymerase. Chungjung Chou, Douglas D Young, Alexander Deiters Angew Chem Int Ed Engl 2009 new
Effects of the K65R and K65R/M184V reverse transcriptase mutations in subtype C HIV on enzyme function and drug resistance. Hong-Tao Xu, Jorge L Martinez-Cajas, Michel L Ntemgwa, Dimitrios Coutsinos, Fernando A Frankel, Bluma G Brenner, Mark A. Wainberg Retrovirology 2009 new
Altered hematopoiesis in mice lacking DNA polymerase mu is due to inefficient double-strand break repair. Daniel Lucas, Beatriz Escudero, José Manuel Ligos, Jose Carlos Segovia, Juan Camilo Estrada, Gloria Terrados, Luis Blanco, Enrique Samper, Antonio Bernad PLoS Genet 2009 new
Structural insights into yeast DNA polymerase delta by small angle X-ray scattering. Rinku Jain, Michal Hammel, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Journal of molecular biology 2009 new
Apricitabine does not select additional drug resistance mutations in tissue culture in human immunodeficiency virus type 1 variants containing K65R, M184V, or M184V plus thymidine analogue mutations. Maureen Oliveira, Daniela D Moisi, Bonnie Spira, Susan Cox, Bluma G Brenner, Mark A. Wainberg Antimicrobial agents and chemotherapy 2009 new
The unfolding clinical spectrum of POLG mutations. M J Blok, B J van den Bosch, E Jongen, A Hendrickx, C E de Die-Smulders, J E Hoogendijk, E Brusse, M de Visser, B T Poll-The, J Bierau, I F de Coo, H J Smeets Journal of medical genetics 2009 pols set
Template usage is responsible for the preferential acquisition of the K65R reverse transcriptase mutation in subtype C variants of human immunodeficiency virus type 1. Dimitrios Coutsinos, Cédric F Invernizzi, Hongtao Xu, Daniela D Moisi, Maureen Oliveira, Bluma G Brenner, Mark A. Wainberg Journal of virology 2009 pols set
Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. Peng Zhan, Xinyong Liu, Junjie Zhu, Zengjun Fang, Zhongjie Li, Christophe Pannecouque, Erik De Clercq Bioorganic & medicinal chemistry 2009 pols set
Characterization of the 5' to 3' nuclease activity of Thermus aquaticus DNA polymerase on fluorogenic double-stranded probes. Qiuying Huang, Qingge Li Mol Cell Probes 2009 complete Qingge Li*
Lesion bypass of N2-ethylguanine by human DNA polymerase iota. Matthew G Pence, Patrick Blans, Charles N Zink, Thomas Hollis, James C Fishbein, Fred W Perrino The Journal of biological chemistry 2009 topics set
Synthesis and in vitro anti-HIV evaluation of a new series of 6-arylmethyl-substituted S-DABOs as potential non-nucleoside HIV-1 reverse transcriptase inhibitors. Yue-Ping Wang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque European journal of medicinal chemistry 2009 pols set
Quinazolin-2-ylamino-quinazolin-4-ols as novel non-nucleoside inhibitors of bacterial DNA polymerase III. Joseph W Guiles, Xicheng Sun, Ian A Critchley, Urs Ochsner, Ming Tregay, Kim Stone, Jennifer Bertino, Louis S Green, Rob Sabin, Frank Dean, H Garry Dallmann, Charles S McHenry, Nebojsa Janjic Bioorganic & medicinal chemistry letters 2009 new
Conformational changes during nucleotide selection by Sulfolobus solfataricus DNA polymerase Dpo4. Robert Lawton Eoff, Raymundo Sanchez-Ponce, F Peter Guengerich The Journal of biological chemistry 2009 pols set
The nucleoside analogue D-carba T blocks HIV-1 reverse transcription. Paul L Boyer, B Christie Vu, Zandrea Ambrose, John G Julias, Svenja Warnecke, Chenzhong Liao, Chris Meier, Victor E Marquez, Stephen H Hughes Journal of medicinal chemistry 2009 pols set
Novel application of Phi29 DNA polymerase: RNA detection and analysis in vitro and in situ by target RNA-primed RCA. Arunas Lagunavicius, Egle Merkiene, Zivile Kiveryte, Agne Savaneviciute, Vilma Zimbaite-Ruskuliene, Tomas Radzvilavicius, Arvydas Janulaitis RNA 2009 pols set
DNA synthesis across an abasic lesion by human DNA polymerase iota. Deepak T Nair, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Structure (London, England : 1993) 2009 topics set
Human DNA polymerase theta possesses 5'-dRP lyase activity and functions in single-nucleotide base excision repair in vitro. Rajendra Prasad, Matthew J Longley, Farida S Sharief, Esther W Hou, William C Copeland, Samuel H Wilson Nucleic acids research 2009 pols set
Distinct beta-clamp interactions govern the activities of the Y family PolIV DNA polymerase. Jérôme E Wagner, Hélène Etienne, Robert P P Fuchs, Agnes M Cordonnier, Dominique Y Burnouf Molecular microbiology 2009 complete Jérôme E Wagner*
Modulation of the structure, catalytic activity, and fidelity of African swine fever virus DNA polymerase X by a reversible disulfide switch. Markus W Voehler, Robert Lawton Eoff, W Hayes McDonald, F Peter Guengerich, Michael P Stone The Journal of biological chemistry 2009 new
DNA polymerase zeta is essential for hexavalent chromium-induced mutagenesis. Travis J O'Brien, Preston Witcher, Bradford Brooks, Steven R Patierno Mutation research 2009 new
Open-system thermodynamic analysis of DNA polymerase fidelity. Field Cady, Hong Qian Phys Biol 2009 new
Mutation Rates and Intrinsic Fidelity of Retroviral Reverse Transcriptases L Menéndez-Arias Viruses 2009 complete ? ?*
Characterization of intein homing endonuclease encoded in the DNA polymerase gene of Thermococcus marinus. Heejin Bae, Kee Pum Kim, Jung Min Song, Jun-Hwan Kim, Joo-Sung Yang, Suk-Tae Kwon FEMS Microbiol Lett 2009 new
Defective interaction between Pol2p and Dpb2p, subunits of DNA polymerase epsilon, contributes to a mutator phenotype in Saccharomyces cerevisiae. Malgorzata Jaszczur, Justyna Rudzka, Joanna Kraszewska, Krzysztof Flis, Piotr Polaczek, Judith L Campbell, I Fijalkowska, Piotr Jonczyk Mutation research 2009 pols set
DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice. Tina M Albertson, Masanori Ogawa, James M Bugni, Laura E Hays, Yang Chen, Yanping Wang, Piper M Treuting, John A Heddle, Robert E Goldsby, Bradley D Preston Proceedings of the National Academy of Sciences of the United States of America 2009 topics set
A novel electrochemical biosensor based on dynamic polymerase-extending hybridization for E. coli O157:H7 DNA detection. Lijiang Wang, Qingjun Liu, Zhaoying Hu, Yongqing Zhang, Chunsheng Wu, Mo Yang, Ping Wang Talanta 2009 pols set
3D architecture of DNA Pol alpha reveals the functional core of multi-subunit replicative polymerases. Sebastian Klinge, Rafael Núñez-Ramírez, Oscar Llorca, Luca Pellegrini The EMBO journal 2009 topics set
Design of peptide-based inhibitors for human immunodeficiency virus type 1 strains resistant to T-20. Kazuki Izumi, Eiichi N Kodama, Kazuya Shimura, Yasuko Sakagami, Kentaro Watanabe, Saori Ito, Tsuyoshi Watabe, Yukihiro Terakawa, Hiroki Nishikawa, Stefan G Sarafianos, Kazuo Kitaura, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka The Journal of biological chemistry 2009 pols set
Cloning and characterization of DNA polymerase eta from Trypanosoma cruzi: roles for translesion bypass of oxidative damage. Michelle Barbi de Moura, Bruno Luiz Fonseca Schamber-Reis, Danielle Gomes Passos Silva, Matheus Andrade Rajão, Andréa Mara Macedo, Glória Regina Franco, Sérgio Danilo Junho Pena, Santuza Maria Ribeiro Teixeira, Carlos Renato Machado Environ Mol Mutagen 2009 complete Carlos Renato Machado*
Disease mutations in the human mitochondrial DNA polymerase thumb subdomain impart severe defects in mitochondrial DNA replication. Rajesh Kasiviswanathan, Matthew J Longley, Sherine S L Chan, William C Copeland The Journal of biological chemistry 2009 new
A DNA polymerase-{alpha}{middle dot}primase cofactor with homology to replication protein A-32 regulates DNA replication in mammalian cells. Darren E Casteel, Shunhui Zhuang, Ying Zeng, Fred W Perrino, Gerry R Boss, Mehran Goulian, Renate B Pilz The Journal of biological chemistry 2009 new
Inhibition of translesion DNA polymerase by archaeal reverse gyrase. Anna Valenti, Giuseppe Perugino, Takehiko Nohmi, Mosè Rossi, Maria Ciaramella Nucleic acids research 2009 complete Maria Ciaramella*
The efficiency and fidelity of 8-oxo-guanine bypass by DNA polymerases delta and eta. Scott D McCulloch, Robert J Kokoska, Parie Garg, Peter M J Burgers, Thomas A Kunkel Nucleic acids research 2009 pols set
Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity. Zhigang Guo, Li Zheng, Huifang Dai, Mian Zhou, Hong Xu, Binghui Shen Nucleic acids research 2009 pols set
Unnatural imidazopyridopyrimidine:naphthyridine base pairs: selective incorporation and extension reaction by Deep Vent (exo- ) DNA polymerase. Shintaro Ogata, Mayumi Takahashi, Noriaki Minakawa, Akira Matsuda Nucleic acids research 2009 partial results
Controllable expansion of primary cardiomyocytes by reversible immortalization. Yongqing Zhang, Edem Nuglozeh, Fatouma Touré, Ann Marie Schmidt, Gordana Vunjak-Novakovic Human gene therapy 2009 new
DNA polymerase delta is required for early mammalian embryogenesis. Arikuni Uchimura, Yuko Hidaka, Takahiro Hirabayashi, Masumi Hirabayashi, Takeshi Yagi PloS one 2009 complete Arikuni Uchimura*
The application of phosphoramidate protide technology to acyclovir confers anti-HIV inhibition. Marco Derudas, Davide Carta, Andrea Brancale, Christophe Vanpouille, Andrea Lisco, Leonid Margolis, Jan Balzarini, Christopher McGuigan Journal of medicinal chemistry 2009 pols set
Analysis of the association of the human cytomegalovirus DNA polymerase subunit UL44 with the viral DNA replication factor UL84. Blair L Strang, Elisa Sinigalia, Laurie A Silva, Donald M Coen, Arianna Loregian J Virol 2009 pols set
HIV inactivation by cross-linking of photo-labeled anti-retroviral compounds with HIV reverse transcriptase. Susan P Colby-Germinario, Adan Rios, Jorge Quesada, Dallas Anderson, Allan L Goldstein, Theresa Fossum, Mark A. Wainberg Vaccine 2009 pols set
Characterization of DNA polymerase X from Thermus thermophilus HB8 reveals the POLXc and PHP domains are both required for 3'-5' exonuclease activity. Shuhei Nakane, Noriko Nakagawa, Seiki Kuramitsu, Ryoji Masui Nucleic acids research 2009 topics set
SEMG-1 expression in early stage chronic lymphocytic leukemia. Sharif Uddin Ahmed, Farouk Meklat, Masum Shahriar, Jian Zhang, Suhkrob Mastulov, Thomas Giannakouros, Andrew Jewell, Yongqing Zhang, Seah H Lim Cytotherapy 2009 new
A model for DNA polymerase switching involving a single cleft and the rim of the sliding clamp. Justin M H Heltzel, Robert W Maul, Sarah K Scouten Ponticelli, Mark D Sutton Proceedings of the National Academy of Sciences of the United States of America 2009 topics set
Specific inhibitors of mammalian DNA polymerase species. Yoshiyuki Mizushina Biosci Biotechnol Biochem 2009 pols set
Structure of HIV-1 reverse transcriptase with the inhibitor beta-Thujaplicinol bound at the RNase H active site. Daniel M Himmel, Karen A Maegley, Tom A Pauly, Joseph David Bauman, Kalyan Das, Chhaya Dharia, Arthur D Clark, Kevin Ryan, Michael J Hickey, Robert A Love, Stephen H Hughes, Simon Bergqvist, Edward Arnold Structure (London, England : 1993) 2009 partial results
A novel triple-regulated oncolytic adenovirus carrying PDCD5 gene exerts potent antitumor efficacy on common human leukemic cell lines. Min Xie, Ji-Hong Niu, Yan Chang, Qi-Jun Qian, Hong-Ping Wu, Lin-Fang Li, Yongqing Zhang, Jin-Lan Li, Xiao-Jun Huang, Guo-Rui Ruan Apoptosis : an international journal on programmed cell death 2009 new
High fidelity and lesion bypass capability of human DNA polymerase delta. Michael W Schmitt, Yoshihiro Matsumoto, Lawrence A Loeb Biochimie 2009 pols set
Direct and indirect roles of RECQL4 in modulating base excision repair capacity. Shepherd H Schurman, Mohammad Hedayati, Zhengqiang Wang, Dharmendra Kumar Singh, Elzbieta Speina, Yongqing Zhang, Kevin Becker, Margaret Macris, Patrick Sung, David M Wilson, Deborah L Croteau, Vilhelm A Bohr Human molecular genetics 2009 new
Human immunodeficiency virus type 1 recombinant reverse transcriptase enzymes containing the G190A and Y181C resistance mutations remain sensitive to etravirine. Hongtao Xu, Yudong Quan, Bluma G Brenner, Tamara Bar-Magen, Maureen Oliveira, Susan M Schader, Mark A. Wainberg Antimicrobial agents and chemotherapy 2009 pols set
The 3'-to-5' exonuclease activity of vaccinia virus DNA polymerase is essential and plays a role in promoting virus genetic recombination. Don B Gammon, David H Evans J Virol 2009 complete David H Evans*
The steric gate amino acid tyrosine 112 is required for efficient mismatched-primer extension by human DNA polymerase kappa. Naoko Niimi, Akira Sassa, Atsushi Katafuchi, Petr Grúz, Hirofumi Fujimoto, Radha-Rani Bonala, Francis Johnson, Toshihiro Ohta, Takehiko Nohmi Biochemistry 2009 pols set
DNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients. Omer Ziv, Nicholas E Geacintov, Satoshi Nakajima, Akira Yasui, Zvi Livneh Proceedings of the National Academy of Sciences of the United States of America 2009 new
Archaeal eukaryote-like Orc1/Cdc6 initiators physically interact with DNA polymerase B1 and regulate its functions. Lu Zhang, Lei Zhang, Yi Liu, Shifan Yang, Chunhui Gao, Hongchao Gong, Ying Feng, Zheng-Guo He Proceedings of the National Academy of Sciences of the United States of America 2009 new
Replication stress leads to genome instabilities in Arabidopsis DNA polymerase delta mutants. David Schuermann, Olivier Fritsch, Jan M Lucht, Barbara Hohn Plant Cell 2009 complete David Schuermann*
Different behaviors in vivo of mutations in the beta hairpin loop of the DNA polymerases of the closely related phages T4 and RB69. Anna Trzemecka, Danuta Płochocka, Anna Bebenek Journal of molecular biology 2009 partial results
Structure and activity relationship of monogalactosyl diacylglycerols, which selectively inhibited in vitro mammalian replicative DNA polymerase activity and human cancer cell growth. Yuki Matsui, Takahiko Hada, Naoki Maeda, Yoshihiro Sato, Yasuhiro Yamaguchi, Toshifumi Takeuchi, Masaharu Takemura, Fumio Sugawara, Kengo Sakaguchi, Hiromi Yoshida, Yoshiyuki Mizushina Cancer Lett 2009 pols set
Electronic control of DNA polymerase binding and unbinding to single DNA molecules. Noah A Wilson, Robin Abu-Shumays, Brett Gyarfas, Hongyun Wang, Kate R Lieberman, Mark Akeson, William B Dunbar ACS nano 2009 complete Kate R Lieberman*
Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition. Stefan G Sarafianos, Bruno Marchand, Kalyan Das, Daniel M Himmel, Michael A. Parniak, Stephen H Hughes, Edward Arnold Journal of molecular biology 2009 pols set
Structural insight into translesion synthesis by DNA Pol II. Feng Wang, Wei Wen Yang Cell 2009 topics set
Expression of herpes simplex virus type 1 DNA polymerase by recombinant vaccinia virus. Ralf Kronenwett, Klaus Weisshart, Charles W Knopf Virus genes 2009 new
Site-specific labeling of T7 DNA polymerase with a conformationally sensitive fluorophore and its use in detecting single-nucleotide polymorphisms. Yu-Chih Tsai, Zhinan Jin, Kenneth A Johnson Analytical biochemistry 2009 pols set
A novel interaction between human DNA polymerase eta and MutLalpha. Rie Kanao, Fumio Hanaoka, Chikahide Masutani Biochem Biophys Res Commun 2009 pols set
Unnatural imidazopyridopyrimidine:naphthyridine base pairs: selective incorporation and extension reaction by DNA polymerases. Noriaki Minakawa, Shintaro Ogata, Mayumi Takahashi, Akira Matsuda Nucleic Acids Symp Ser (Oxf) 2009 topics set
Indolylarylsulfones bearing natural and unnatural amino acids. Discovery of potent inhibitors of HIV-1 non-nucleoside wild type and resistant mutant strains reverse transcriptase and coxsackie B4 virus. Francesco Piscitelli, Antonio Coluccia, Andrea Brancale, Giuseppe La Regina, Anna Sansone, Cesare Giordano, Jan Balzarini, Giovanni Maga, Samantha Zanoli, Alberta Samuele, Roberto Cirilli, Francesco La Torre, Antonio Lavecchia, Ettore Novellino, Romano Silvestri Journal of medicinal chemistry 2009 pols set
Reaction mechanism of the epsilon subunit of E. coli DNA polymerase III: insights into active site metal coordination and catalytically significant residues. G Andrés Cisneros, Lalith Perera, Roel M Schaaper, Lars C Pedersen, Robert E London, Lee G Pedersen, Thomas A Darden Journal of the American Chemical Society 2009 pols set
Replication past the N5-methyl-formamidopyrimidine lesion of deoxyguanosine by DNA polymerases and an improved procedure for sequence analysis of in vitro bypass products by mass spectrometry. Plamen P Christov, Karen C Angel, F Peter Guengerich, Carmelo J Rizzo Chemical research in toxicology 2009 pols set
TopBP1 and DNA polymerase alpha-mediated recruitment of the 9-1-1 complex to stalled replication forks: implications for a replication restart-based mechanism for ATR checkpoint activation. Shan Yan, W Matthew Michael Cell Cycle 2009 new
Novel POLG1 mutations associated with neuromuscular and liver phenotypes in adults and children. Joanna D Stewart, S Tennant, H Powell, A Pyle, E L Blakely, L He, Gavin Hudson, M Roberts, D du Plessis, D Gow, L D Mewasingh, M G Hanna, S Omer, A A Morris, R Roxburgh, J H Livingston, Robert McFarland, Douglass M Turnbull, Patrick F Chinnery, Robert W Taylor Journal of medical genetics 2009 pols set
Telbivudine, a nucleoside analog inhibitor of HBV polymerase, has a different in vitro cross-resistance profile than the nucleotide analog inhibitors adefovir and tenofovir. Maria Seifer, April Patty, Ilaria Serra, Bin Li, David N Standring Antiviral Res 2009 topics set
DNA polymerase beta and PARP activities in base excision repair in living cells. Aya Masaoka, Julie K Horton, William A Beard, Samuel H Wilson DNA repair 2009 new
MtDNA mutations are a common cause of severe disease phenotypes in children with Leigh syndrome. Karin Naess, Christoph Freyer, Helene Bruhn, Rolf Wibom, Gunilla Malm, Inger Nennesmo, Ulrika von Döbeln, Nils-Göran Larsson Biochimica et biophysica acta 2009 topics set
Mitochondrial DNA depletion and fatal infantile hepatic failure due to mutations in the mitochondrial polymerase gamma (POLG) gene A combined morphological/enzyme histochemical and immunocytochemical/biochemical and molecular genetic study. J Müller-Höcker, R Horvath, S Schäfer, H Hessel, W Müller-Felber, J Kühr, William C Copeland, P Seibel Journal of cellular and molecular medicine 2009 new
Role of the 2-amino group of purines during dNTP polymerization by human DNA polymerase alpha. Jennifer N Patro, Milan Urban, Robert D Kuchta Biochemistry 2009 pols set
Relationship between polymerase gamma (POLG) polymorphisms and antiretroviral therapy-induced lipodystrophy in HIV-1 infected patients: a case-control study. Franck Chiappini, Elina Teicher, Raphaël Saffroy, Brigitte Debuire, Daniel Vittecoq, Antoinette Lemoine Current HIV research 2009 pols set
DNA polymerase gamma and mitochondrial disease: understanding the consequence of POLG mutations. Sherine S L Chan, William C Copeland Biochimica et biophysica acta 2009 new
Genomic analyses of recombinant adenovirus type 11a in China. Zhaohui Yang, Zhen Zhu, Liuying Tang, Li Wang, Xiaojuan Tan, Pengbo Yu, Yong Zhang, Xiaoping Tian, Jingjun Wang, Yan Ming Zhang, Dexin Li, Wenbo Xu Journal of clinical microbiology 2009 new
Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase iota. Kevin N Kirouac, Hong Ling The EMBO journal 2009 topics set
RB69 DNA polymerase mutants with expanded nascent base-pair-binding pockets are highly efficient but have reduced base selectivity. Haijiang Zhang, Jeff W Beckman, Jianhong Wang, William H Konigsberg Biochemistry 2009 complete
Efficiency and specificity of microRNA-primed nucleotide analog incorporation by various DNA polymerases. Younguk Sun, Kalvin J Gregory, Val Golovlev Anal Biochem 2009 topics set
Probing conformational changes of human DNA polymerase lambda using mass spectrometry-based protein footprinting. Jason D Fowler, Jessica A Brown, Mamuka Kvaratskhelia, Zucai Suo Journal of molecular biology 2009 pols set
Mapping the position of DNA polymerase-bound DNA templates in a nanopore at 5 A resolution. Brett Gyarfas, Felix Olasagasti, Seico Benner, Daniel R Garalde, Kate R Lieberman, Mark Akeson ACS nano 2009 complete Kate R Lieberman*
A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome. Agnieszka Gambus, Frederick van Deursen, Dimitrios Polychronopoulos, Magdalena Foltman, Richard C Jones, Ricky D Edmondson, Arturo Calzada, Karim Labib The EMBO journal 2009 new
Expression pattern of dmrt4 from olive flounder (Paralichthys olivaceus) in adult gonads and during embryogenesis. Aiyun Wen, Feng You, Xungang Tan, Peng Sun, Jing Ni, Yongqing Zhang, Dongdong Xu, Zhihao Wu, Yongli Xu, Peiming Zhang Fish physiology and biochemistry 2009 new
DNA damage alters DNA polymerase delta to a form that exhibits increased discrimination against modified template bases and mismatched primers. Xiao Meng, Yanjiao Zhou, Sufang Zhang, Ernest Y C Lee, David N Frick, Marietta Y W T Lee Nucleic acids research 2009 topics set
A variable neurodegenerative phenotype with polymerase gamma mutation. S Stricker, H Prüss, R Horvath, Enrico Baruffini, Tiziana Lodi, E Siebert, M Endres, R Zschenderlein, A Meisel Journal of neurology, neurosurgery, and psychiatry 2009 pols set
DNA polymerase X from Deinococcus radiodurans implicated in bacterial tolerance to DNA damage is characterized as a short patch base excision repair polymerase. Nivedita P Khairnar, Hari S Misra Microbiology 2009 pols set
Highly error-free role of DNA polymerase eta in the replicative bypass of UV-induced pyrimidine dimers in mouse and human cells. Jung-Hoon Yoon, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2009 new
Crystal structure of epstein-barr virus DNA polymerase processivity factor BMRF1. Kazutaka Murayama, Sanae Nakayama, Miyuki Kato-Murayama, Ryogo Akasaka, Naomi Ohbayashi, Yuki Kamewari-Hayami, Takaho Terada, Mikako Shirouzu, Tatsuya Tsurumi, Shigeyuki Yokoyama The Journal of biological chemistry 2009 new
Alpha,beta-difluoromethylene deoxynucleoside 5'-triphosphates: a convenient synthesis of useful probes for DNA polymerase beta structure and function. Thomas G Upton, Boris A Kashemirov, Charles E McKenna, Myron F Goodman, G K Surya Prakash, Roman Kultyshev, Vinod K Batra, David D Shock, Lars C Pedersen, William A Beard, Samuel H Wilson Org Lett 2009 topics set
Two novel POLG mutations causing hepatic mitochondrial DNA depletion with recurrent hypoketotic hypoglycaemia and fatal liver dysfunction. B Bortot, E Barbi, S Biffi, G Lunazzi, R Bussani, A Burlina, S Norbedo, A Ventura, M Carrozzi, G M Severini Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2009 pols set
A new DNA polymerase I from Geobacillus caldoxylosilyticus TK4: cloning, characterization, and mutational analysis of two aromatic residues. Cemal Sandalli, Kamalendra Singh, Mukund J Modak, Amit Ketkar, Sabriye Canakci, Ismail Demir, Ali Osman Belduz Appl Microbiol Biotechnol 2009 new
Mutations in mitochondrial DNA polymerase-gamma promote breast tumorigenesis. Keshav K Singh, Vanniarajan Ayyasamy, Kjerstin M Owens, Manika Sapru Koul, Marija Vujcic Journal of human genetics 2009 pols set
Digenic mutations in severe myoclonic epilepsy of infancy. Maija Bolszak, Anna-Kaisa Anttonen, Tuomas Komulainen, Reetta Hinttala, Salla Pakanen, Raija Sormunen, Riitta Herva, Anna-Elina Lehesjoki, Kari Majamaa, Heikki Rantala, Johanna Uusimaa Epilepsy research 2009 complete Johanna Uusimaa*
A novel inhibitor of DNA polymerase beta enhances the ability of temozolomide to impair the growth of colon cancer cells. Aruna S Jaiswal, Sanjeev Banerjee, Harekrushna Panda, Charles D Bulkin, Tadahide Izumi, Fazlul H Sarkar, David A Ostrov, Satya Narayan Mol Cancer Res 2009 new
Elucidating the kinetic mechanism of DNA polymerization catalyzed by Sulfolobus solfataricus P2 DNA polymerase B1. Jessica A Brown, Zucai Suo Biochemistry 2009 new
[Construction and application of a genechip method for detection of hepatitis B virus lamivudine-resistant mutants and basal core promotor/Pre-C mutants]. Bing Li, Bo-Ping Zhou, Jin-Fu Peng, Li-Yan Chen, Weiming Zhang, Wei Tang, Zhao-Qin Wang, Zhong-Hua Yin, Liu-Mei Xu, Rui-Ling Luo, Xiao-He Li, Sai-Yun Liu Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 2009 new
Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants. Dai-Shi Su, John J Lim, Elizabeth Tinney, Bang-Lin Wan, Mary Beth Young, Kenneth D Anderson, Deanne Rudd, Vandna Munshi, Carolyn Bahnck, Peter J Felock, Meiqing Lu, Ming-Tain Lai, Sinoeun Touch, Gregory Moyer, Daniel J Distefano, Jessica A Flynn, Yuexia Liang, Rosa Sanchez, Sridhar Prasad, Youwei Yan, Rebecca A Perlow-Poehnelt, Maricel Torrent, Michael D Miller, Joe P Vacca, Theresa M Williams, Neville J Anthony Bioorganic & medicinal chemistry letters 2009 partial results
Specific targeting of highly conserved residues in the HIV-1 reverse transcriptase primer grip region. 2. Stereoselective interaction to overcome the effects of drug resistant mutations. Stefania Butini, Margherita Brindisi, Sandro Cosconati, Luciana Marinelli, Giuseppe Borrelli, Salvatore Sanna Coccone, Anna Ramunno, Giuseppe Campiani, Ettore Novellino, Samantha Zanoli, Alberta Samuele, Gianluca Giorgi, Alberto Bergamini, Michela Di Mattia, Silvana Lalli, Bruno Galletti, Sandra Gemma, Giovanni Maga Journal of medicinal chemistry 2009 pols set
Coupling DNA unwinding activity with primer synthesis in the bacteriophage T4 primosome. Maria Manosas, Michelle M Spiering, Zhihao Zhuang, Stephen J Benkovic, Vincent Croquette Nat Chem Biol 2009 topics set
Proofreading dynamics of a processive DNA polymerase. Borja Ibarra, Yann R Chemla, Sergey Plyasunov, Steven B Smith, José María Lázaro, Margarita Salas, Carlos Bustamante The EMBO journal 2009 new
Comparative purification strategies for Drosophila and human mitochondrial DNA replication proteins: DNA polymerase gamma and mitochondrial single-stranded DNA-binding protein. Marcos T Oliveira, Laurie S Kaguni Methods in molecular biology (Clifton, N.J.) 2009 new
Limited terminal transferase in human DNA polymerase mu defines the required balance between accuracy and efficiency in NHEJ. Paula Andrade, María José Martín, Raquel Juárez, Francisco López de Saro, Luis Blanco Proceedings of the National Academy of Sciences of the United States of America 2009 pols set
Ethanol-tolerant Saccharomyces cerevisiae strains isolated under selective conditions by over-expression of a proofreading-deficient DNA polymerase delta. Hiroko Abe, Yasuko Fujita, Yuki Takaoka, Eri Kurita, Shuntaro Yano, Naotaka Tanaka, Ken-ichi Nakayama J Biosci Bioeng 2009 new
DNA polymerase kappa from Trypanosoma cruzi localizes to the mitochondria, bypasses 8-oxoguanine lesions and performs DNA synthesis in a recombination intermediate. Matheus Andrade Rajão, D G Passos-Silva, Wanderson Duarte DaRocha, Glória Regina Franco, Andréa Mara Macedo, Sérgio Danilo Junho Pena, Santuza Maria Ribeiro Teixeira, Carlos Renato Machado Molecular microbiology 2009 complete Carlos Renato Machado*
Nucleic acid polymerases use a general acid for nucleotidyl transfer. Christian Castro, Eric D Smidansky, Jamie J Arnold, Kenneth R Maksimchuk, Ibrahim Moustafa, Akira Uchida, Matthias Götte, William H Konigsberg, Craig E Cameron Nature structural & molecular biology 2009 new
R964C mutation of DNA polymerase gamma imparts increased stavudine toxicity by decreasing nucleoside analog discrimination and impairing polymerase activity. Christopher M Bailey, Rajesh Kasiviswanathan, William C Copeland, Karen S Anderson Antimicrob Agents Chemother 2009 topics set
Replication across template T/U by human DNA polymerase-iota. Rinku Jain, Deepak T Nair, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Structure (London, England : 1993) 2009 topics set
The reopening rate of the fingers domain is a determinant of base selectivity for RB69 DNA polymerase. Harold R Lee, Michael Wang, William H Konigsberg Biochemistry 2009 complete
Identification of a novel REV1-interacting motif necessary for DNA polymerase kappa function. Eiji Ohashi, Tomo Hanafusa, Keijiro Kamei, Ihnyoung Song, Junya Tomida, Hiroshi Hashimoto, Cyrus Vaziri, Haruo Ohmori Genes Cells 2009 pols set
Isolation of recombinant DNA elongation proteins. Barbara van Loon, Elena Ferrari, Ulrich Hübscher Methods in molecular biology (Clifton, N.J.) 2009 new
Discovery of chiral cyclopropyl dihydro-alkylthio-benzyl-oxopyrimidine (S-DABO) derivatives as potent HIV-1 reverse transcriptase inhibitors with high activity against clinically relevant mutants. Marco Radi, Giovanni Maga, Maddalena Alongi, Lucilla Angeli, Alberta Samuele, Samantha Zanoli, Luca Bellucci, Andrea Tafi, Gianni Casaluce, Gianluca Giorgi, Mercedes Armand-Ugon, Emmanuel Gonzalez, José A Esté, Mireille Baltzinger, Guillaume Bec, Philippe Dumas, Eric Ennifar, Maurizio Botta Journal of medicinal chemistry 2009 pols set
Penicilliols A and B, novel inhibitors specific to mammalian Y-family DNA polymerases. Takuma Kimura, Toshifumi Takeuchi, Yuko Kumamoto-Yonezawa, Eiji Ohashi, Haruo Ohmori, Chikahide Masutani, Fumio Hanaoka, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Bioorganic & medicinal chemistry 2009 pols set
High-cell density shake-flask expression and rapid purification of the large fragment of Thermus aquaticus DNA polymerase I using a new chemically and temperature inducible expression plasmid in Escherichia coli. J W Brandis, Kenneth A Johnson Protein expression and purification 2009 topics set
Distribution and roles of X-family DNA polymerases in eukaryotes. Yukinobu Uchiyama, Ryo Takeuchi, Hirofumi Kodera, Kengo Sakaguchi Biochimie 2009 new
SC29EK, a peptide fusion inhibitor with enhanced alpha-helicity, inhibits replication of human immunodeficiency virus type 1 mutants resistant to enfuvirtide. Takeshi Naito, Kazuki Izumi, Eiichi N Kodama, Yasuko Sakagami, Keiko Kajiwara, Hiroki Nishikawa, Kentaro Watanabe, Stefan G Sarafianos, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka Antimicrobial agents and chemotherapy 2009 pols set
Mitochondrial mosaics in the liver of 3 infants with mtDNA defects. Frank Roels, Patrick Verloo, François Eyskens, Baudouin François, Sara Seneca, Boel De Paepe, Jean-Jacques Martin, Valerie Meersschaut, Marleen Praet, Emmanuel Scalais, Marc Espeel, Joél Smet, Gert Van Goethem, Rudy Van Coster BMC clinical pathology 2009 pols set
Ataxia with ophthalmoplegia or sensory neuropathy is frequently caused by POLG mutations. Claudia Schulte, Matthis Synofzik, Thomas Gasser, Ludger Schöls Neurology 2009 pols set
Translesion DNA polymerases remodel the replisome and alter the speed of the replicative helicase. Chiara Indiani, Lance D Langston, Olga Yurieva, Myron F Goodman, Mike E O'Donnell Proceedings of the National Academy of Sciences of the United States of America 2009 new
Human DNA polymerase eta is required for common fragile site stability during unperturbed DNA replication. Laurie Rey, Julia M Sidorova, Nadine Puget, François Boudsocq, Denis S F Biard, Raymond J Monnat, Christophe Cazaux, Jean-Sébastien Hoffmann Molecular and cellular biology 2009 pols set
Global conformational dynamics of a Y-family DNA polymerase during catalysis. Cuiling Xu, Brian A Maxwell, Jessica A Brown, Likui Zhang, Zucai Suo PLoS Biol 2009 topics set
Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases. Olga Rechkoblit, Lucy Malinina, Yuan Cheng, Nicholas E Geacintov, Suse Broyde, Dinshaw J Patel Structure (London, England : 1993) 2009 topics set
Mitochondrial DNA depletion in progressive external ophthalmoplegia caused by POLG1 mutations. Charalampos Tzoulis, M Papingji, T Fiskestrand, L S Røste, Laurence A Bindoff Acta neurologica Scandinavica. Supplementum 2009 pols set
Investigation of stoichiometry of T4 bacteriophage helicase loader protein (gp59). Sri Ranjini Arumugam, Tae-Hee Lee, Stephen J Benkovic The Journal of biological chemistry 2009 topics set
Clinical reasoning: Blurred vision and dancing feet: restless legs syndrome presenting in mitochondrial disease. H Aitken, G Gorman, Robert McFarland, M Roberts, Robert W Taylor, Douglass M Turnbull Neurology 2009 pols set
Mutations in the gene 5 DNA polymerase of bacteriophage T7 suppress the dominant lethal phenotype of gene 2.5 ssDNA binding protein lacking the C-terminal phenylalanine. Boriana Marintcheva, Udi Qimron, Yao Yu, Stanley Tabor, Charles C Richardson, Charles C Richardson Molecular microbiology 2009 pols set
Structural and functional elucidation of the mechanism promoting error-prone synthesis by human DNA polymerase kappa opposite the 7,8-dihydro-8-oxo-2'-deoxyguanosine adduct. Adriana Irimia, Robert Lawton Eoff, F Peter Guengerich, Martin Egli The Journal of biological chemistry 2009 topics set
Template strand scrunching during DNA gap repair synthesis by human polymerase lambda. Miguel Garcia-Diaz, Katarzyna Bebenek, Andres A Larrea, Jody M Havener, Lalith Perera, Joseph M Krahn, Lars C Pedersen, Dale A Ramsden, Thomas A Kunkel Nature structural & molecular biology 2009 new
Clinical and molecular features of mitochondrial DNA depletion syndromes. A Spinazzola, Federica Invernizzi, Franco Carrara, Eleonora Lamantea, Alice Donati, M Dirocco, I Giordano, M Meznaric-Petrusa, Enrico Baruffini, Iliana Ferrero, Massimo Zeviani Journal of inherited metabolic disease 2009 pols set
Involvement of specialized DNA polymerases in mutagenesis by 8-hydroxy-dGTP in human cells. Kazuya Satou, Mika Hori, Kazuaki Kawai, Hiroshi Kasai, Hideyoshi Harashima, Hiroyuki Kamiya DNA repair 2009 topics set
Polymerization fidelity of a replicative DNA polymerase from the hyperthermophilic archaeon Sulfolobus solfataricus P2. Likui Zhang, Jessica A Brown, Sean A Newmister, Zucai Suo Biochemistry 2009 topics set
C-terminal phenylalanine of bacteriophage T7 single-stranded DNA-binding protein is essential for strand displacement synthesis by T7 DNA polymerase at a nick in DNA. Sharmistha Ghosh, Boriana Marintcheva, Masateru Takahashi, Charles C Richardson The Journal of biological chemistry 2009 pols set
Inhibition of translation by a short element in the 5' leader of the herpes simplex virus 1 DNA polymerase transcript. Kevin F Bryant, Donald M Coen Journal of virology 2008 new
DNA polymerases and human disease. Lawrence A Loeb, Raymond J Monnat Nature reviews. Genetics 2008 new
Rapid detection and identification of a pathogen's DNA using Phi29 DNA polymerase. Yun Xu, Simon Gao, John F Bruno, Benjamin J Luft, John J Dunn Biochem Biophys Res Commun 2008 pols set
Crystal structures of HIV-1 reverse transcriptase complexes with thiocarbamate non-nucleoside inhibitors. Andrea Spallarossa, Sara Cesarini, Angelo Ranise, Marco Ponassi, Torsten Unge, Martino Bolognesi Biochem Biophys Res Commun 2008 partial results
The solution structure of the amino-terminal domain of human DNA polymerase epsilon subunit B is homologous to C-domains of AAA+ proteins. Tarmo Nuutinen, Helena Tossavainen, Kai Fredriksson, Päivi Pirilä, Perttu Permi, Helmut Pospiech, Juhani E Syvaoja Nucleic acids research 2008 topics set
Efficient and accurate bypass of N2-(1-carboxyethyl)-2'-deoxyguanosine by DinB DNA polymerase in vitro and in vivo. Bifeng Yuan, Huachuan Cao, Yanan Jiang, Haizheng Hong, Yinsheng Wang Proceedings of the National Academy of Sciences of the United States of America 2008 new
Control of DNA polymerase lambda stability by phosphorylation and ubiquitination during the cell cycle. Ursula Wimmer, Elena Ferrari, Peter Hunziker, Ulrich Hübscher EMBO Rep 2008 new
Substrate-induced DNA strand misalignment during catalytic cycling by DNA polymerase lambda. Katarzyna Bebenek, Miguel Garcia-Diaz, Meredith C Foley, Lars C Pedersen, Tamar Schlick, Thomas A Kunkel EMBO Rep 2008 topics set
Design of annulated pyrazoles as inhibitors of HIV-1 reverse transcriptase. Zachary K Sweeney, Seth F Harris, Seth F Arora, Hassan Javanbakht, Yingqian Li, Jennifer Fretland, James P Davidson, J Roland Billedeau, Shelley K Gleason, Donald R Hirschfeld, Joshua J Kennedy-Smith, Taraneh Mirzadegan, Ralf Roetz, Mark Smith, Sarah Sperry, Judy M Suh, Jeffrey Wu, Stan Tsing, Armando G Villaseñor, Amber Paul, Guoping Su, Gabrielle M Heilek, Julie Qi Hang, Amy S Zhou, Jesper A Jernelius, Fang-Jie Zhang, Klaus Klumpp J Med Chem 2008 partial results
The replicative DNA polymerase of herpes simplex virus 1 exhibits apurinic/apyrimidinic and 5'-deoxyribose phosphate lyase activities. Federica Bogani, Paul E Boehmer Proceedings of the National Academy of Sciences of the United States of America 2008 new
Quantification of VEGF-C expression in canine mammary tumours. C Qiu, D D Lin, H H Wang, C H Qiao, Jiqun Wang, Tao Zhang Australian veterinary journal 2008 new
Nucleotide selectivity opposite a benzo[a]pyrene-derived N2-dG adduct in a Y-family DNA polymerase: a 5'-slippage mechanism. Pingna Xu, Lida Oum, Nicholas E Geacintov, Suse Broyde Biochemistry 2008 topics set
Mechanism of double-base lesion bypass catalyzed by a Y-family DNA polymerase. Jessica A Brown, Sean A Newmister, Kevin A Fiala, Zucai Suo Nucleic acids research 2008 topics set
Rice exonuclease-1 homologue, OsEXO1, that interacts with DNA polymerase lambda and RPA subunit proteins, is involved in cell proliferation. Tomoyuki Furukawa, Tomohiro Imamura, Hiroko K Kitamoto, Hiroaki Shimada Plant Mol Biol 2008 new
Two translesion synthesis DNA polymerase genes, AtPOLH and AtREV1, are involved in development and UV light resistance in Arabidopsis. María Jesús Santiago, Encarna Alejandre-Durán, Andrés Muñoz-Serrano, Manuel Ruiz-Rubio J Plant Physiol 2008 new
DNA polymerase kappa produces interrupted mutations and displays polar pausing within mononucleotide microsatellite sequences. Suzanne E Hile, Kristin A Eckert Nucleic acids research 2008 new
Uracil recognition by replicative DNA polymerases is limited to the archaea, not occurring with bacteria and eukarya. Josephine Wardle, Peter M J Burgers, Isaac K O Cann, Kate Darley, Pauline Heslop, Erik Johansson, Li-Jung Lin, Peter McGlynn, Jonathan Sanvoisin, Carrie M W Stith, Bernard A Connolly Nucleic acids research 2008 new
On the inhibitory affect of some dementia drugs on DNA polymerase Beta activity. V N Vyjayanti, N S Chary, Kalluri Subba Rao Neurochem Res 2008 new
Editing of misaligned 3'-termini by an intrinsic 3'-5' exonuclease activity residing in the PHP domain of a family X DNA polymerase. Benito Baños, José María Lázaro, Laurentino Villar, Margarita Salas, Miguel de Vega Nucleic acids research 2008 partial results
Determination of DNA polymerase and nuclease activities of DNA-dependent polymerases using fluorescence detection under real-time conditions. A G Bragin, S A Glushkov, M K Ivanov, A A Krasnov, G M Dymshits Biochemistry (Mosc) 2008 new
Amino acid mutation N348I in the connection subdomain of human immunodeficiency virus type 1 reverse transcriptase confers multiclass resistance to nucleoside and nonnucleoside reverse transcriptase inhibitors. Atsuko Hachiya, Eiichi N Kodama, Stefan G Sarafianos, Matthew M Schuckmann, Yasuko Sakagami, Masao Matsuoka, Masafumi Takiguchi, Hiroyuki Gatanaga, Shinichi Oka J Virol 2008 topics set
Roles of PCNA-binding and ubiquitin-binding domains in human DNA polymerase eta in translesion DNA synthesis. Narottam Acharya, Jung-Hoon Yoon, Himabindu Gali, Ildiko Unk, Lajos Haracska, Robert E Johnson, Jerard Hurwitz, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2008 pols set
Insights into the replisome from the structure of a ternary complex of the DNA polymerase III alpha-subunit. Richard A Wing, Scott Bailey, Thomas A Steitz Journal of molecular biology 2008 topics set
Opposed steric constraints in human DNA polymerase beta and E. coli DNA polymerase I. Francesca Di Pasquale, Daniela Fischer, Dina Grohmann, Tobias Restle, Armin Geyer, Andreas Marx Journal of the American Chemical Society 2008 pols set
Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors. Jingshan Ren, Phillip P Chamberlain, Anna Stamp, Steven A Short, Kurt L Weaver, Karen R Romines, Richard J Hazen, Andrew Freeman, Robert G Ferris, C Webster Andrews, Lawrence R Boone, Joseph H Chan, David K Stammers J Med Chem 2008 partial results
Duality of polynucleotide substrates for Phi29 DNA polymerase: 3'-->5' RNase activity of the enzyme. Arunas Lagunavicius, Zivile Kiveryte, Vilma Zimbaite-Ruskuliene, Tomas Radzvilavicius, Arvydas Janulaitis RNA 2008 partial results
Experimental evidence that a DNA polymerase can incorporate N7-platinated guanines to give platinated DNA. Michele Benedetti, Cosimo Ducani, Danilo Migoni, Daniela Antonucci, Vita M Vecchio, Antonella Ciccarese, Alessandro Romano, Tiziano Verri, Giuseppe Ciccarella, Francesco P Fanizzi Angew Chem Int Ed Engl 2008 new
The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations. Thomas J Tucker, Sandeep Saggar, John T Sisko, Robert M Tynebor, Theresa M Williams, Peter J Felock, Jessica A Flynn, Ming-Tain Lai, Yuexia Liang, Georgia B McGaughey, Meiquing Liu, Michael D Miller, Gregory Moyer, Vandna Munshi, Rebecca A Perlow-Poehnelt, Sridhar Prasad, Rosa Sanchez, Maricel Torrent, Joseph P Vacca, Bang-Lin Wan, Youwei Yan Bioorganic & medicinal chemistry letters 2008 partial results
Discovery and optimization of pyridazinone non-nucleoside inhibitors of HIV-1 reverse transcriptase. Zachary K Sweeney, James P Dunn, Yingqian Li, Gabrielle M Heilek, Pete W Dunten, Todd R Elworthy, Xiaochun Han, Seth F Harris, Donald R Hirschfeld, J Heather Hogg, Walter Huber, Ann C Kaiser, Denis J Kertesz, Woongki Kim, Taraneh Mirzadegan, Michael G Roepel, Y David Saito, Tania M P C Silva, Steven Swallow, Jahari L Tracy, Armando Villasenor, Harit Vora, Amy S Zhou, Klaus Klumpp Bioorganic & medicinal chemistry letters 2008 partial results
Characterization of a Bacillus subtilis 64-kDa DNA polymerase X potentially involved in DNA repair. Benito Baños, José María Lázaro, Laurentino Villar, Margarita Salas, Miguel de Vega Journal of molecular biology 2008 complete
Hymenoic acid, a novel specific inhibitor of human DNA polymerase lambda from a fungus of Hymenochaetaceae sp. Masayuki Nishida, Noriko Ida, Mao Horio, Toshifumi Takeuchi, Shinji Kamisuki, Hiroshi Murata, Kouji Kuramochi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Bioorg Med Chem 2008 pols set
DNA polymerase eta reduces the gamma-H2AX response to psoralen interstrand crosslinks in human cells. Seiki Mogi, Christina E Butcher, Dennis H Oh Exp Cell Res 2008 new
Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside reverse transcriptase inhibitors. Anna-Maria Monforte, Angela Rao, Patrizia Logoteta, Stefania Ferro, Laura De Luca, Maria Letizia Barreca, Nunzio Iraci, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Alba Chimirri Bioorganic & medicinal chemistry 2008 pols set
Escherichia coli mismatch repair protein MutL interacts with the clamp loader subunits of DNA polymerase III. Feng Li, Qin Liu, Yuan-Yuan Chen, Zi-Niu Yu, Zhi-Ping Zhang, Ya-Feng Zhou, Jiao-Yu Deng, Li-Jun Bi, Xian-En Zhang Mutation research 2008 pols set
Mutant DNA polymerase for improved detection of single-nucleotide variations in microarrayed primer extension. Ramon Kranaster, Patrick Ketzer, Andreas Marx Chembiochem 2008 new
Characterization of a replicative DNA polymerase mutant with reduced fidelity and increased translesion synthesis capacity. Xuejun Zhong, Lars C Pedersen, Thomas A Kunkel Nucleic acids research 2008 topics set
Dpb2p, a noncatalytic subunit of DNA polymerase epsilon, contributes to the fidelity of DNA replication in Saccharomyces cerevisiae. Malgorzata Jaszczur, Krzysztof Flis, Justyna Rudzka, Joanna Kraszewska, Martin E Budd, Piotr Polaczek, Judith L Campbell, Piotr Jonczyk, I Fijalkowska Genetics 2008 pols set
Significance of stereochemistry of 3'-terminal phosphorothioate-modified primer in DNA polymerase-mediated chain extension. Barbara Nawrot, Natasha Paul, Beata Rebowska, Wojciech J Stec Mol Biotechnol 2008 new
Synthesis and biological evaluation of novel 6-substituted 5-alkyl-2-(arylcarbonylmethylthio)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. Yue-Ping Wang, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Bioorganic & medicinal chemistry 2008 pols set
Inhibitory effects of vitamin K3 on DNA polymerase and angiogenesis. Kiminori Matsubara, Tomoko Kayashima, Masaharu Mori, Hiromi Yoshida, Yoshiyuki Mizushina Int J Mol Med 2008 new
Peptide ligands specific to the oxidized form of Escherichia coli thioredoxin. Michael D Scholle, Bridget S Banach, Samir M Hamdan, Charles C Richardson, Brian K Kay Biochimica et biophysica acta 2008 pols set
Inhibitory effects of cholesterol derivatives on DNA polymerase and topoisomerase activities, and human cancer cell growth. Chisato Ishimaru, Yuko Yonezawa, Isoko Kuriyama, Masayuki Nishida, Hiromi Yoshida, Yoshiyuki Mizushina Lipids 2008 new
Protein phosphatase-1 is targeted to DNA polymerase delta via an interaction with the p68 subunit. Yan Gao, Yanjiao Zhou, Bin Xie, Sufang Zhang, Amal A Rahmeh, Hua-Shan Huang, Marietta Y W T Lee, Ernest Y C Lee Biochemistry 2008 pols set
Uracil recognition in archaeal DNA polymerases captured by X-ray crystallography. Susan J Firbank, Josephine Wardle, Pauline Heslop, Richard J Lewis, Bernard A Connolly Journal of molecular biology 2008 topics set
Lesion processing: high-fidelity versus lesion-bypass DNA polymerases. Suse Broyde, Liming Wang, Olga Rechkoblit, Nicholas E Geacintov, Dinshaw J Patel Trends in biochemical sciences 2008 topics set
Initial crystallographic study of human PCNA in complex with a peptide containing the noncanonical PIP-box sequence of human DNA polymerase iota. Asami Hishiki, Toshiyuki Shimizu, Tomo Hanafusa, Haruo Ohmori, Mamoru Sato, Hiroshi Hashimoto Acta Crystallogr Sect F Struct Biol Cryst Commun 2008 pols set
Unique substrate spectrum and PCR application of Nanoarchaeum equitans family B DNA polymerase. Jeong Jin Choi, Jae-Geun Song, Ki Hoon Nam, Jong Il Lee, Heejin Bae, Gun A Kim, Younguk Sun, Suk-Tae Kwon Appl Environ Microbiol 2008 new
DNA polymerase beta-catalyzed-PCNA independent long patch base excision repair synthesis: a mechanism for repair of oxidatively damaged DNA ends in post-mitotic brain. Wei Wei, Ella W Englander J Neurochem 2008 new
The specific inhibitory effect of demethoxydehydroaltenusin, a derivative of dehydroaltenusin, on mammalian DNA polymerase alpha. Isoko Kuriyama, Keishi Fukudome, Shinji Kamisuki, Kouji Kuramochi, Kazunori Tsubaki, Kengo Sakaguchi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Int J Mol Med 2008 pols set
Human DNA polymerase iota protects cells against oxidative stress. Tirzah Braz Petta, Satoshi Nakajima, Anastasia Zlatanou, Emmanuelle Despras, Sophie Couve-Privat, Alexander Ishchenko, Alain Sarasin, Akira Yasui, Patricia L Kannouche The EMBO journal 2008 pols set
Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpoint. Huiqiang Lou, Makiko Komata, Yuki Katou, Zhiyun Guan, Clara C Reis, Martin E Budd, Katsuhiko Shirahige, Judith L Campbell Molecular cell 2008 new
Triazole derivatives as non-nucleoside inhibitors of HIV-1 reverse transcriptase--structure-activity relationships and crystallographic analysis. Thorsten A Kirschberg, Mini Balakrishnan, Wei Huang, Rebecca Hluhanich, Nilima Kutty, Albert C Liclican, Damian J McColl, Neil H Squires, Eric B Lansdon Bioorganic & medicinal chemistry letters 2008 partial results
Targeting human DNA polymerase alpha for the inhibition of keratinocyte proliferation. Part 1. Homology model, active site architecture and ligand binding. Anja Richartz, Monika Höltje, Birte Brandt, Monika Schäfer-Korting, Hans-Dieter Höltje J Enzyme Inhib Med Chem 2008 pols set
Overproduction of Escherichia coli DNA polymerase DinB (Pol IV) inhibits replication fork progression and is lethal. Kaori Uchida, Asako Furukohri, Yutaka Shinozaki, Tetsuya Mori, Daichi Ogawara, Shigehiko Kanaya, Takehiko Nohmi, Hisaji Maki, Masahiro Tatsumi Akiyama Molecular microbiology 2008 pols set
Stem-loop silencing reveals that a third mitochondrial DNA polymerase, POLID, is required for kinetoplast DNA replication in trypanosomes. Julian Chandler, Anthula V Vandoros, Brian Mozeleski, Michele M Klingbeil Eukaryot Cell 2008 new
An AP endonuclease 1-DNA polymerase beta complex: theoretical prediction of interacting surfaces. Alexej Abyzov, Alper Uzun, Phyllis R Strauss, Valentin A Ilyin PLoS Comput Biol 2008 new
Protein-template-directed synthesis across an acrolein-derived DNA adduct by yeast Rev1 DNA polymerase. Deepak T Nair, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Structure (London, England : 1993) 2008 new
Comparison of the growth kinetics of neuropathogenic and nonneuropathogenic equid herpesvirus type 1 (EHV-1) strains in cultured murine neuronal cells and the relevance of the D/N(752) coding change in DNA polymerase gene (ORF30). Souichi Yamada, Tomio Matsumura, Koji Tsujimura, Tsuyoshi Yamaguchi, Kenji Ohya, Hideto Fukushi J Vet Med Sci 2008 new
Non-nucleoside HIV-1 reverse-transcriptase inhibitors. Part 10. Synthesis and anti-HIV activity of 5-alkyl-6-(1-naphthylmethyl)pyrimidin-4(3H)-ones with a mono- or disubstituted 2-amino function as novel 'dihydro-alkoxy-benzyl-oxopyrimidine' (DABO) analogues. Yueping Wang, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque Chemistry & biodiversity 2008 pols set
Crystal engineering of HIV-1 reverse transcriptase for structure-based drug design. Joseph David Bauman, Kalyan Das, William C Ho, Mukta Baweja, Daniel M Himmel, Arthur D Clark, Deena A Oren, Paul L Boyer, Stephen H Hughes, Aaron J Shatkin, Edward Arnold Nucleic acids research 2008 partial results
Phosphorylation of the C subunit (p66) of human DNA polymerase delta. Laure Lemmens, Serge Urbach, Renaud Prudent, Claude Cochet, Giuseppe Baldacci, Patrick Hughes Biochem Biophys Res Commun 2008 pols set
Cell cycle phase dependent role of DNA polymerase beta in DNA repair and survival after ionizing radiation. Christie Vermeulen, Manon Verwijs-Janssen, Adrian C Begg, Conchita Vens Radiother Oncol 2008 new
Increased expression of the adult stem cell marker Musashi-1 in endometriosis and endometrial carcinoma. Matthias Götte, M Wolf, A Staebler, O Buchweitz, Reinhard Kelsch, A N Schüring, Ludwig Kiesel J Pathol 2008 new
New DNA polymerase IIIC inhibitors: 3-subtituted anilinouracils with potent antibacterial activity in vitro and in vivo. Niels Svenstrup, Kerstin Ehlert, Christoph Ladel, Alexander Kuhl, Dieter Häbich ChemMedChem 2008 new
DNA polymerase zeta (pol zeta) in higher eukaryotes. GregoryN Gan, JohnP Wittschieben, BirgitteØ Wittschieben, RichardD Wood Cell research 2008 topics set
Translesion synthesis of 7,8-dihydro-8-oxo-2'-deoxyguanosine by DNA polymerase eta in vivo. Dong-Hyun Lee, Gerd P Pfeifer Mutation research 2008 new
Multiple-sited amyloidosis in the upper aerodigestive tract: case report and literature review. Gustavo Haruo Passerotti, Marcello Caniello, Adriana Hachiya, Patrícia P Santoro, Rui Imamura, Domingos H Tsuji Braz J Otorhinolaryngol 2008 new
Human DNA polymerase eta activity and translocation is regulated by phosphorylation. Yih-Wen Chen, James E Cleaver, Zafer Hatahet, Richard E Honkanen, Jang-Yang Chang, Yun Yen, Kai-Ming Chou Proceedings of the National Academy of Sciences of the United States of America 2008 pols set
High-fidelity DNA polymerase enhances the sensitivity of a peptide nucleic acid clamp PCR assay for K-ras mutations. Bjørnar Gilje, Reino Heikkilä, Satu Oltedal, Kjersti Tjensvoll, Oddmund Nordgård J Mol Diagn 2008 new
An investigation of the effects of nanosize delivery system for antisense oligonucleotide on esophageal squamous cancer cells. Huixiang Li, Jin Wang, Tianyang Zhou, Yongqing Zhang, Zhenzhong Zhang Cancer biology & therapy 2008 new
New strategies for DNA polymerase library screening. Ramon Kranaster, Andreas Marx Nucleic Acids Symp Ser (Oxf) 2008 new
Division of labor at the eukaryotic replication fork. Stephanie A Nick McElhinny, Dmitry A Gordenin, Carrie M W Stith, Peter M J Burgers, Thomas A Kunkel Molecular cell 2008 new
Induction of a:T mutations is dependent on cellular environment but independent of mutation frequency and target gene location. Akiko Ukai, Konomi Ishimaru, Rika Ouchida, Hiromi Mori, Chie Kano, Toshiyuki Moritan, Ji-Yang Wang Journal of immunology (Baltimore, Md. : 1950) 2008 new
[Mutations of HBV polymerase gene sequence in lamivudine-resistant chronic hepatitis B patients]. Cheng Wang, Jian Sun, Jin-jun Chen, Zhan-hui Wang, Jin-lin Hou Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2008 new
Human telomerase reverse transcriptase expression correlates with vascular endothelial growth factor-promoted tumor cell proliferation in prostate cancer. Jie Tang, Zhengqiang Wang, Xincang Li, Jinming Li, Huaiyin Shi Artificial cells, blood substitutes, and immobilization biotechnology 2008 new
A single-molecule nanopore device detects DNA polymerase activity with single-nucleotide resolution. Scott L Cockroft, John Chu, Manuel Amorin, M Reza Ghadiri Journal of the American Chemical Society 2008 new
Single-stranded DNA-binding protein recruits DNA polymerase V to primer termini on RecA-coated DNA. Gali Arad, Ayal Hendel, Claus Urbanke, Ute Curth, Zvi Livneh The Journal of biological chemistry 2008 new
Human methyl purine DNA glycosylase and DNA polymerase beta expression collectively predict sensitivity to temozolomide. Ram N Trivedi, Xiao-Hong Wang, Elena Jelezcova, Eva M Goellner, Jiang-bo Tang, Robert W Sobol Mol Pharmacol 2008 new
Alpha,beta-methylene-2'-deoxynucleoside 5'-triphosphates as noncleavable substrates for DNA polymerases: isolation, characterization, and stability studies of novel 2'-deoxycyclonucleosides, 3,5'-cyclo-dG, and 2,5'-cyclo-dT. Fengting Liang, Nidhi Jain, Troy Hutchens, David D Shock, William A Beard, Samuel H Wilson, M Paul Chiarelli, Bongsup P Cho J Med Chem 2008 topics set
Atrial fibrillation: an unusual cause. H J Siebelink, Tineke P Willems, M J W Götte Neth Heart J 2008 new
[Activity of error-prone DNA polymerase iota in different periods of house mouse Mus musculus ontogeny]. Alena V Makarova, Leonid V Gening, Irina V Makarova, Vyacheslav Z Tarantul Ontogenez 2008 new
Hyper-phosphorylated retinoblastoma protein suppresses telomere elongation. Masaharu Takemura, Kazuto Sugimura, Katsuzumi Okumura, Siripan Limsirichaikul, Motoshi Suzuki, Yoshiji Yamada, Shonen Yoshida Bioscience, biotechnology, and biochemistry 2008 new
Production of the soluble form of KIT, s-KIT, abolishes stem cell factor-induced melanogenesis in human melanocytes. Shinya Kasamatsu, Akira Hachiya, Kazuhiko Higuchi, Atsushi Ohuchi, Takashi Kitahara, Raymond E Boissy J Invest Dermatol 2008 new
Partial reconstitution of DNA large loop repair with purified proteins from Saccharomyces cerevisiae. Debbie Sommer, Carrie M W Stith, Peter M J Burgers, Robert S Lahue Nucleic acids research 2008 new
Tolerance for 8-oxoguanine but not thymine glycol in alignment-based gap filling of partially complementary double-strand break ends by DNA polymerase lambda in human nuclear extracts. Rui-Zhe Zhou, Luis Blanco, Miguel Garcia-Diaz, Katarzyna Bebenek, Thomas A Kunkel, Lawrence F Povirk Nucleic acids research 2008 new
The Asp285 variant of DNA polymerase beta extends mispaired primer termini via increased nucleotide binding. Drew L Murphy, Jessica L Kosa, Joachim Jaeger, Joann B Sweasy Biochemistry 2008 new
Quantum dot FRET biosensors that respond to pH, to proteolytic or nucleolytic cleavage, to DNA synthesis, or to a multiplexing combination. Miho Suzuki, Yuzuru Husimi, Hirokazu Komatsu, Koji Suzuki, Kenneth T Douglas Journal of the American Chemical Society 2008 new
Initiation of DNA replication by a third parallel DNA strand bound in a triple-helix manner leads to strand invasion. Patrick P Lestienne, François Boudsocq, Jacques E Bonnet Biochemistry 2008 topics set
DNA polymerase-catalyzed DNA network growth. Sascha Keller, Jianhong Wang, Madhaviah Chandra, Rüdiger Berger, Andreas Marx Journal of the American Chemical Society 2008 new
Requirement of Rad5 for DNA polymerase zeta-dependent translesion synthesis in Saccharomyces cerevisiae. Vincent Pagès, Anne Bresson, Narottam Acharya, Satya Prakash, Robert P P Fuchs, Louise Prakash Genetics 2008 new
Crystal structure of Pfu, the high fidelity DNA polymerase from Pyrococcus furiosus. Suhng Wook Kim, Dong-Uk Kim, Jin Kwang Kim, Lin-Woo Kang, Hyun-Soo Cho Int J Biol Macromol 2008 topics set
Selective targeting of the HIV-1 reverse transcriptase catalytic complex through interaction with the "primer grip" region by pyrrolobenzoxazepinone non-nucleoside inhibitors correlates with increased activity towards drug-resistant mutants. Samantha Zanoli, Sandra Gemma, Stefania Butini, Margherita Brindisi, Bhupendra P Joshi, Giuseppe Campiani, Caterina Fattorusso, Marco Persico, Emmanuele Crespan, Reynel Cancio, Silvio Spadari, Ulrich Hübscher, Giovanni Maga Biochemical pharmacology 2008 pols set
Inhibitors of DNA polymerase beta: activity and mechanism. Zhijie Gao, David J Maloney, Larisa M Dedkova, Sidney M Hecht Bioorg Med Chem 2008 new
Synthesis and DNA-polymerase incorporation of colored 4-selenothymidine triphosphate for polymerase recognition and DNA visualization. Julianne Caton-Williams, Zhen Huang Angew Chem Int Ed Engl 2008 new
Kinetic analysis of correct nucleotide insertion by a Y-family DNA polymerase reveals conformational changes both prior to and following phosphodiester bond formation as detected by tryptophan fluorescence. Jeff W Beckman, Qixin Wang, F Peter Guengerich The Journal of biological chemistry 2008 partial results
A pre-RNA candidate revisited: both enantiomers of flexible nucleoside triphosphates are DNA polymerase substrates. Benjamin D Heuberger, Christopher Switzer Journal of the American Chemical Society 2008 new
DNA polymerase bypass in vitro and in E. coli of a C-nucleotide analogue of Fapy-dG. Yvonne N Weledji, Carissa J Wiederholt, Michael O Delaney, Marc M Greenberg Bioorg Med Chem 2008 pols set
X-ray structure of the complex of regulatory subunits of human DNA polymerase delta. Andrey G Baranovskiy, Nigar D Babayeva, Victoria G Liston, Igor B Rogozin, Eugene V Koonin, Youri I Pavlov, Dmitry G Vassylyev, Tahir H Tahirov Cell Cycle 2008 pols set
Discovery of 3-{5-[(6-amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5 -chlorobenzonitrile (MK-4965): a potent, orally bioavailable HIV-1 non-nucleoside reverse transcriptase inhibitor with improved potency against key mutant viruses. Thomas J Tucker, John T Sisko, Robert M Tynebor, Theresa M Williams, Peter J Felock, Jessica A Flynn, Ming-Tain Lai, Yuexia Liang, Georgia B McGaughey, Meiquing Liu, Michael D Miller, Gregory Moyer, Vandna Munshi, Rebecca A Perlow-Poehnelt, Sridhar Prasad, John C Reid, Rosa Sanchez, Maricel Torrent, Joseph P Vacca, Bang-Lin Wan, Youwei Yan J Med Chem 2008 partial results
Structure of a mutant form of proliferating cell nuclear antigen that blocks translesion DNA synthesis. Bret D Freudenthal, S Ramaswamy, Manju M Hingorani, M Todd Washington Biochemistry 2008 new
Xeroderma pigmentosum-variant patients from America, Europe, and Asia. Hiroki Inui, Kyu-Seon Oh, Carine Nadem, Takahiro Ueda, Sikandar G Khan, Ahmet Metin, Engin Gozukara, Steffen Emmert, Hanoch Slor, David B Busch, Carl C Baker, John J DiGiovanna, Deborah Tamura, Cornelia S Seitz, Alexei Gratchev, Wen Hao Wu, Kee Yang Chung, Hye Jin Chung, Esther Azizi, Roger Woodgate, Thomas D Schneider, Kenneth H Kraemer The Journal of investigative dermatology 2008 new
Identification of a Taq DNA polymerase inhibitor from the red seaweed Symphyocladia latiuscula. Hyung Joo Jin, Mi Young Oh, Deuk Hee Jin, Yong Ki Hong J Environ Biol 2008 pols set
Incorrect nucleotide insertion at the active site of a G:A mismatch catalyzed by DNA polymerase beta. Ping Lin, Vinod K Batra, Lars C Pedersen, William A Beard, Samuel H Wilson, Lee G Pedersen Proceedings of the National Academy of Sciences of the United States of America 2008 topics set
Recent advances in the research of HIV-1 RNase H inhibitors. Fang Yu, Xinyong Liu, Peng Zhan, Erik De Clercq Mini reviews in medicinal chemistry 2008 pols set
Emerging antiviral drugs. Erik De Clercq Expert opinion on emerging drugs 2008 pols set
Reduced levels of DNA polymerase delta induce chromosome fragile site instability in yeast. Francene J Lemoine, Natasha P Degtyareva, Robert J Kokoska, Thomas D Petes Molecular and cellular biology 2008 new
Flexibility of eukaryotic Okazaki fragment maturation through regulated strand displacement synthesis. Carrie M W Stith, Joan F Sterling, Michael A Resnick, Dmitry A Gordenin, Peter M J Burgers The Journal of biological chemistry 2008 new
Anti-tumor effect of orally administered spinach glycolipid fraction on implanted cancer cells, colon-26, in mice. Naoki Maeda, Yasuo Kokai, Seiji Ohtani, Hiroeki Sahara, Yuko Kumamoto-Yonezawa, Isoko Kuriyama, Takahiko Hada, Noriyuki Sato, Hiromi Yoshida, Yoshiyuki Mizushina Lipids 2008 new
Novel indole-3-sulfonamides as potent HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs). Zhijian Zhao, Scott E Wolkenberg, Philip E J Sanderson, Meiqing Lu, Vandna Munshi, Gregory Moyer, Meizhen Feng, Anthony V Carella, Linda T Ecto, Lori J Gabryelski, Ming-Tain Lai, Sridar G Prasad, Youwei Yan, Georgia B McGaughey, Michael D Miller, Craig W Lindsley, George D Hartman, Joseph P Vacca, Theresa M Williams Bioorganic & medicinal chemistry letters 2008 partial results
Near full-length genomic analysis of a novel subtype A1/C recombinant HIV type 1 isolate from Canada. Michel L Ntemgwa, Thomas D'Aquin Toni, Bluma G Brenner, Jean-Pierre Routy, Daniela D Moisi, Maureen Oliveira, Mark A. Wainberg AIDS research and human retroviruses 2008 pols set
Whole genome amplification with Phi29 DNA polymerase to enable genetic or genomic analysis of samples of low DNA yield. Kaisa Silander, Janna Saarela Methods in molecular biology (Clifton, N.J.) 2008 pols set
Replication bypass of interstrand cross-link intermediates by Escherichia coli DNA polymerase IV. Anuradha Kumari, Irina G Minko, Michael B Harbut, Steven E Finkel, Myron F Goodman, R Stephen Lloyd The Journal of biological chemistry 2008 pols set
2-(2,6-Dihalo-phenyl)-3-heteroaryl-2-ylmethyl-1, 3-thiazolidin-4-ones: anti-HIV agents. Ravindra K Rawal, Rajkamal Tripathi, Smitha Kulkarni, R Paranjape, S B Katti, Christophe Pannecouque, Erik De Clercq Chemical biology & drug design 2008 pols set
A comparison of BRCT domains involved in nonhomologous end-joining: introducing the solution structure of the BRCT domain of polymerase lambda. Geoffrey A Mueller, Andrea F Moon, Eugene F DeRose, Jody M Havener, Dale A Ramsden, Lars C Pedersen, Robert E London DNA repair 2008 new
Design and synthesis of 2-(2,6-dibromophenyl)-3-heteroaryl-1,3-thiazolidin-4-ones as anti-HIV agents. Ravindra K Rawal, Rajkamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq European journal of medicinal chemistry 2008 pols set
Exonuclease activity of proofreading DNA polymerases is at the origin of artifacts in molecular profiling studies. J Gury, L Zinger, L Gielly, P Taberlet, RA Geremia Electrophoresis 2008 topics set
Solution structures of 2 : 1 and 1 : 1 DNA polymerase-DNA complexes probed by ultracentrifugation and small-angle X-ray scattering. Kuo-Hsiang Tang, Marc Niebuhr, Ann Aulabaugh, Ming-Daw Tsai Nucleic acids research 2008 new
Novel strategies for the site-specific covalent labelling of nucleic acids. Samuel H Weisbrod, Andreas Marx Chemical communications (Cambridge, England) 2008 new
DNA conjugation by Staudinger ligation. Samuel H Weisbrod, Anna Baccaro, Andreas Marx Nucleic acids symposium series (2004) 2008 new
Varied active-site constraints in the klenow fragment of E. coli DNA polymerase I and the lesion-bypass Dbh DNA polymerase. Janina Cramer, Gopinath Rangam, Andreas Marx, Tobias Restle Chembiochem 2008 pols set
DNA polymerase epsilon: a polymerase of unusual size (and complexity). Zachary F Pursell, Thomas A Kunkel Prog Nucleic Acid Res Mol Biol 2008 new
Over-expression of the catalytic core of mitochondrial DNA (mtDNA) polymerase in the nervous system of Drosophila melanogaster reduces median life span by inducing mtDNA depletion. Francisco Martínez-Azorín, Manuel Calleja, Rosana Hernández-Sierra, Carol L Farr, Laurie S Kaguni, Rafael Garesse Journal of neurochemistry 2008 new
Measurement of coronary calcium scores by electron beam computed tomography or exercise testing as initial diagnostic tool in low-risk patients with suspected coronary artery disease. Christiane A Geluk, Riksta Dikkers, Patrick J Perik, René A Tio, Marco J W Götte, Hans L Hillege, Rozemarijn Vliegenthart, Janneke B Houwers, Tineke P Willems, Matthijs Oudkerk, Felix Zijlstra Eur Radiol 2008 new
Interaction between DNA Polymerase lambda and RPA during translesion synthesis. Yu S Krasikova, Ekaterina A Belousova, Natalia A Lebedeva, P E Pestryakov, Olga I Lavrik Biochemistry (Mosc) 2008 new
RAD18 signals DNA polymerase IOTA to stalled replication forks in cells entering S-phase with DNA damage. Shelly Kakar, Nicholas B Watson, William Glenn McGregor Adv Exp Med Biol 2008 new
New DNA polymerase from the hyperthermophilic marine archaeon Thermococcus thioreducens. Damien Marsic, Jean-Michel Flaman, Joseph D Ng Extremophiles 2008 new
[Down-regulative expression of microRNAs cluster in human colon tumorigenesis]. Yi Ba, Xing Cai, Xi Chen, Yuan Yin, Yongqing Zhang, Chen-yu Zhang Zhonghua yi xue za zhi 2008 new
[Proliferative capacity of mesenchymal stem cells from human fetal bone marrow and their ability to differentiate into the derivative cell types of three embryonic germ layers]. Yue-Chun Wang, Yongqing Zhang Sheng li xue bao : [Acta physiologica Sinica] 2008 new
Regulation of polymerase exchange between Poleta and Poldelta by monoubiquitination of PCNA and the movement of DNA polymerase holoenzyme. Zhihao Zhuang, Robert E Johnson, Lajos Haracska, Louise Prakash, Satya Prakash, Stephen J Benkovic Proceedings of the National Academy of Sciences of the United States of America 2008 new
Role for DNA polymerase kappa in the processing of N2-N2-guanine interstrand cross-links. Irina G Minko, Michael B Harbut, Ivan D Kozekov, Albena Kozekova, Petra M Jakobs, Susan B Olson, Robb E Moses, Thomas M Harris, Carmelo J Rizzo, R Stephen Lloyd The Journal of biological chemistry 2008 new
Fingers-closing and other rapid conformational changes in DNA polymerase I (Klenow fragment) and their role in nucleotide selectivity. Catherine M Joyce, Olga Potapova, Angela M DeLucia, Xuanwei Huang, Vandana Purohit Basu, Nigel D F Grindley Biochemistry 2008 complete
AAV-mediated TRAIL gene expression driven by hTERT promoter suppressed human hepatocellular carcinoma growth in mice. Yongqing Zhang, Hong Ma, Jinchun Zhang, Shilian Liu, Yanxin Liu, Dexian Zheng Life sciences 2008 new
The mitochondrial genome of the Basidiomycete fungus Pleurotus ostreatus (oyster mushroom). Yong Wang, Fanya Zeng, Chung Chau Hon, Yongqing Zhang, Frederick Chi Ching Leung FEMS microbiology letters 2008 new
Reversible valproate hepatotoxicity due to mutations in mitochondrial DNA polymerase gamma (POLG1). Robert McFarland, Gavin Hudson, Robert W Taylor, S H Green, S Hodges, P J McKiernan, Patrick F Chinnery, V Ramesh Archives of disease in childhood 2008 pols set
Recent patents of gene sequences relative to DNA polymerases. Linda J Reha-Krantz Recent Pat DNA Gene Seq 2008 complete
Distinct double- and single-stranded DNA binding of E. coli replicative DNA polymerase III alpha subunit. Micah J McCauley, Leila Shokri, Jana Sefcikova, Ceslovas Venclovas, Penny J Beuning, Mark C Williams ACS Chem Biol 2008 pols set
Clonally expanded mitochondrial DNA mutations in epileptic individuals with mutated DNA polymerase gamma. Gábor Zsurka, Miriam Baron, Joanna D Stewart, Cornelia Kornblum, Monika Bös, Robert Sassen, Robert W Taylor, Christian E Elger, Patrick F Chinnery, Wolfram S Kunz Journal of neuropathology and experimental neurology 2008 pols set
Parkinsonism associated with the homozygous W748S mutation in the POLG1 gene. Anne M Remes, Reetta Hinttala, M Kärppä, Heidi Soini, R Takalo, Johanna Uusimaa, Kari Majamaa Parkinsonism & related disorders 2008 pols set
Delayed chain termination protects the anti-hepatitis B virus drug entecavir from excision by HIV-1 reverse transcriptase. Egor P Tchesnokov, Aleksandr Obikhod, Raymond F Schinazi, Matthias Götte The Journal of biological chemistry 2008 complete Bruno Marchand
A DNA polymerase alpha accessory protein, Mcl1, is required for propagation of centromere structures in fission yeast. Toyoaki Natsume, Yasuhiro Tsutsui, Takashi Sutani, Elaine M Dunleavy, Alison L Pidoux, Hiroshi Iwasaki, Katsuhiko Shirahige, Robin C Allshire, Fumiaki Yamao PloS one 2008 new
The I260Q variant of DNA polymerase beta extends mispaired primer termini due to its increased affinity for deoxynucleotide triphosphate substrates. Shibani Dalal, Daniela Starcevic, Joachim Jaeger, Joann B Sweasy Biochemistry 2008 new
A high-throughput and single-tube recombination of crude PCR products using a DNA polymerase inhibitor and type IIS restriction enzyme. Ippei Kotera, Takeharu Nagai J Biotechnol 2008 new
Two novel POLG1 mutations in a patient with progressive external ophthalmoplegia, levodopa-responsive pseudo-orthostatic tremor and parkinsonism. Federica Invernizzi, Sara Varanese, Astrid Thomas, Franco Carrara, Marco Onofrj, Massimo Zeviani Neuromuscular disorders : NMD 2008 pols set
Mechanistic consequences of temperature on DNA polymerization catalyzed by a Y-family DNA polymerase. Kevin A Fiala, Shanen M Sherrer, Jessica A Brown, Zucai Suo Nucleic acids research 2008 topics set
Alpers syndrome with prominent white matter changes. Xinhua Bao, Ye Wu, Lee-Jun C Wong, Yongqing Zhang, Hui Xiong, Ping-Chieh Chou, Cavatina K Truong, Yanan Jiang, Jiong Qin, Yun Yuan, Qing Lin, Xiaoming Wu Brain & development 2008 pols set
Association between trinucleotide CAG repeats of the DNA polymerase gene (POLG) with age of onset of Iranian Friedreich's ataxia patients. Mohammad Mehdi Heidari, Massoud Houshmand, Saman Hosseinkhani, Shahriar Nafissi, Barbara Scheiber-Mojdehkar, Mehri Khatami Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2008 new
Association of the polymorphism of the CAG repeat in the mitochondrial DNA polymerase gamma gene (POLG) with testicular germ-cell cancer. M Blomberg Jensen, Henrik Leffers, Jørgen H Petersen, G Daugaard, Niels E Skakkebaek, Ewa Rajpert-De Meyts Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008 new
Molecular and clinical genetics of mitochondrial diseases due to POLG mutations. Lee-Jun C Wong, Robert K Naviaux, Nicola Brunetti-Pierri, Qing Zhang, Eric S Schmitt, Cavatina K Truong, Margherita Milone, Bruce H Cohen, Beverly Wical, Jaya Ganesh, Alice A Basinger, Barbara K Burton, Kathryn Swoboda, Donald L Gilbert, Adeline Vanderver, Russell P Saneto, Bruno Maranda, Georgianne Arnold, Jose E Abdenur, Paula J Waters, William C Copeland Human mutation 2008 pols set
Long patch base excision repair in mammalian mitochondrial genomes. Bartosz Szczesny, Anne W Tann, Matthew J Longley, William C Copeland, Sankar Mitra The Journal of biological chemistry 2008 complete Bartosz Szczesny*
Novel azaphilones, kasanosins A and B, which are specific inhibitors of eukaryotic DNA polymerases beta and lambda from Talaromyces sp. Takuma Kimura, Masayuki Nishida, Kouji Kuramochi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Bioorganic & medicinal chemistry 2008 pols set
Determinants of coronary microvascular dysfunction in symptomatic hypertrophic cardiomyopathy. Paul Knaapen, Tjeerd Germans, Paolo G Camici, Ornella E Rimoldi, Folkert J ten Cate, Jurrien M ten Berg, Pieter A Dijkmans, Ronald Boellaard, Willem G van Dockum, Marco J W Götte, Jos W R Twisk, Albert C van Rossum, Adriaan A Lammertsma, Frans C Visser Am J Physiol Heart Circ Physiol 2008 new
The proofreading exonuclease subunit epsilon of Escherichia coli DNA polymerase III is tethered to the polymerase subunit alpha via a flexible linker. Kiyoshi Ozawa, Slobodan Jergic, Ah Young Park, Nicholas E Dixon, Gottfried Otting Nucleic acids research 2008 pols set
1-deoxyrubralactone, a novel specific inhibitor of families X and Y of eukaryotic DNA polymerases from a fungal strain derived from sea algae. Mitsuki Naganuma, Masayuki Nishida, Kouji Kuramochi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Bioorganic & medicinal chemistry 2008 pols set
Replication protein A and proliferating cell nuclear antigen coordinate DNA polymerase selection in 8-oxo-guanine repair. Giovanni Maga, Emmanuele Crespan, Ursula Wimmer, Barbara van Loon, Alessandra Amoroso, Chiara Mondello, Cristina Belgiovine, Elena Ferrari, Giada A Locatelli, Giuseppe Villani, Ulrich Hübscher Proceedings of the National Academy of Sciences of the United States of America 2008 pols set
hTERT-targeted RNA interference inhibits tumorigenicity and motility of HCT116 cells. Ying Shen, Yong-Wei Zhang, Zhi-Xiang Zhang, Ze-Hong Miao, Jian Ding Cancer biology & therapy 2008 new
POLG1 mutations manifesting as autosomal recessive axonal Charcot-Marie-Tooth disease. Timothy Harrower, Joanna D Stewart, Gavin Hudson, Henry Houlden, Graham Warner, Dominic G O'Donovan, Leslie J Findlay, Robert W Taylor, Rajith De Silva, Patrick F Chinnery Archives of neurology 2008 pols set
Mismatched dNTP incorporation by DNA polymerase beta does not proceed via globally different conformational pathways. Kuo-Hsiang Tang, Marc Niebuhr, Chang-Shung Tung, Hsiu-Chien Chan, Chia-Cheng Chou, Ming-Daw Tsai Nucleic acids research 2008 topics set
Changes in heparan sulfate are associated with delayed wound repair, altered cell migration, adhesion and contractility in the galactosyltransferase I (beta4GalT-7) deficient form of Ehlers-Danlos syndrome. Matthias Götte, Dorothe Spillmann, George W Yip, Elly Versteeg, Frank G Echtermeyer, Toin H van Kuppevelt, Ludwig Kiesel Hum Mol Genet 2008 new
Induction of centrosome amplification and chromosome instability in p53-deficient lung cancer cells exposed to benzo[a]pyrene diol epoxide (B[a]PDE). Kazuya Shinmura, M Iwaizumi, H Igarashi, K Nagura, Hidetaka Yamada, Motoshi Suzuki, K Fukasawa, Haruhiko Sugimura The Journal of pathology 2008 new
Juvenile Alpers disease. Esko Wiltshire, Guido Davidzon, Salvatore DiMauro, Hasan O Akman, Lynette Sadleir, Lindsay Haas, Jane Zuccollo, Alison McEwen, David R Thorburn Archives of neurology 2008 pols set
Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase by a stavudine analogue, 4'-ethynyl stavudine triphosphate. Guangwei Yang, Jianhong Wang, Yao Cheng, Ginger E Dutschman, Hiromichi Tanaka, Masanori Baba, Yung-Chi Cheng Antimicrobial agents and chemotherapy 2008 pols set
Bisphosphonate inhibitors of ATP-mediated HIV-1 reverse transcriptase catalyzed excision of chain-terminating 3'-azido, 3'-deoxythymidine: a QSAR investigation. Yongcheng Song, Julian M W Chan, Zev Tovian, Aaron Secrest, Eva Nagy, Kilannin Krysiak, Kyle Bergan, Michael A. Parniak, Eric Oldfield Bioorganic & medicinal chemistry 2008 pols set
Snapshots of a Y-family DNA polymerase in replication: substrate-induced conformational transitions and implications for fidelity of Dpo4. Jimson H Y Wong, Kevin A Fiala, Zucai Suo, Hong Ling Journal of molecular biology 2008 topics set
DNA polymerase theta (POLQ) can extend from mismatches and from bases opposite a (6-4) photoproduct. Masayuki Seki, Richard D Wood DNA repair 2008 new
Specificity of mutations induced by incorporation of oxidized dNTPs into DNA by human DNA polymerase eta. Katsuhiko Hidaka, Masami Yamada, Hiroyuki Kamiya, Chikahide Masutani, Hideyoshi Harashima, Fumio Hanaoka, Takehiko Nohmi DNA repair 2008 pols set
Reduced efficiency and increased mutagenicity of translesion DNA synthesis across a TT cyclobutane pyrimidine dimer, but not a TT 6-4 photoproduct, in human cells lacking DNA polymerase eta. Ayal Hendel, Omer Ziv, Quentin Gueranger, Nicholas E Geacintov, Zvi Livneh DNA repair 2008 new
Intrinsic 5'-deoxyribose-5-phosphate lyase activity in Saccharomyces cerevisiae Trf4 protein with a possible role in base excision DNA repair. Lionel Gellon, Dena R Carson, Jonathan P Carson, Bruce Demple DNA repair 2008 topics set
Mechanisms by which herpes simplex virus DNA polymerase limits translesion synthesis through abasic sites. Yali Zhu, Liping Song, Jason Stroud, Deborah S Parris DNA repair 2008 new
Utilization of a deoxynucleoside diphosphate substrate by HIV reverse transcriptase. Scott J Garforth, Michael A. Parniak, Vinayaka R Prasad PloS one 2008 pols set
AKAP149 binds to HIV-1 reverse transcriptase and is involved in the reverse transcription. Julie Lemay, Priscilla Maidou-Peindara, Reynel Cancio, Eric Ennifar, Gaël Coadou, Giovanni Maga, Jean-Christophe Rain, Richard Benarous, Lang Xia Liu Journal of molecular biology 2008 pols set
Mismatched and matched dNTP incorporation by DNA polymerase beta proceed via analogous kinetic pathways. Michelle P Roettger, Marina Bakhtina, Ming-Daw Tsai Biochemistry 2008 partial results
Examining the ribonuclease H primer grip of HIV-1 reverse transcriptase by charge neutralization of RNA/DNA hybrids. Chandravanu Dash, Brian J Scarth, Christopher Badorrek, Matthias Götte, Stuart F J Le Grice Nucleic acids research 2008 pols set
Catalytic mechanism of human DNA polymerase lambda with Mg2+ and Mn2+ from ab initio quantum mechanical/molecular mechanical studies. G Andrés Cisneros, Lalith Perera, Miguel García-Díaz, Katarzyna Bebenek, Thomas A Kunkel, Lee G Pedersen DNA repair 2008 pols set
Interactions of Escherichia coli thioredoxin, the processivity factor, with bacteriophage T7 DNA polymerase and helicase. Sharmistha Ghosh, Samir M Hamdan, Timothy E Cook, Charles C Richardson The Journal of biological chemistry 2008 pols set
Substrate-induced stable enzyme-inhibitor complex formation allows tight binding of novel 2-aminopyrimidin-4(3H)-ones to drug-resistant HIV-1 reverse transcriptase mutants. Alberta Samuele, Marcella Facchini, Dante Rotili, Antonello Mai, Marino Artico, Mercedes Armand-Ugón, José A Esté, Giovanni Maga ChemMedChem 2008 pols set
Role of homodimerization of human cytomegalovirus DNA polymerase accessory protein UL44 in origin-dependent DNA replication in cells. Elisa Sinigalia, Gualtiero Alvisi, Beatrice Mercorelli, Donald M Coen, Gregory S Pari, David A Jans, Alessandro Ripalti, Giorgio Palù, Arianna Loregian Journal of virology 2008 pols set
Structures of DNA polymerase beta with active-site mismatches suggest a transient abasic site intermediate during misincorporation. Vinod K Batra, William A Beard, David D Shock, Lars C Pedersen, Samuel H Wilson Molecular cell 2008 topics set
Homozygous W748S mutation in the POLG1 gene in patients with juvenile-onset Alpers syndrome and status epilepticus. Johanna Uusimaa, Reetta Hinttala, Heikki Rantala, Markku Päivärinta, Riitta Herva, Matias Röyttä, Heidi Soini, Jukka S Moilanen, Anne M Remes, Ilmo E Hassinen, Kari Majamaa Epilepsia 2008 pols set
A multidisciplinary approach for the identification of novel HIV-1 non-nucleoside reverse transcriptase inhibitors: S-DABOCs and DAVPs. Marco Radi, Chiara Falciani, Lorenzo Contemori, Elena Petricci, Giovanni Maga, Alberta Samuele, Samantha Zanoli, Montserrat Terrazas, Marinunzia Castria, Andrea Togninelli, José A Esté, Imma Clotet-Codina, Mercedes Armand-Ugón, Maurizio Botta ChemMedChem 2008 pols set
Depletion of mitochondrial DNA in fibroblast cultures from patients with POLG1 mutations is a consequence of catalytic mutations. Neil Ashley, Anthony O'Rourke, Conrad Smith, Susan Adams, Vasantha Gowda, Massimo Zeviani, Garry K Brown, Carl Fratter, Joanna Poulton Human molecular genetics 2008 pols set
4"-Benzoylureido-TSAO derivatives as potent and selective non-nucleoside HCMV inhibitors. Structure-activity relationship and mechanism of antiviral action. Sonia de Castro, M Teresa Peromingo, Lieve Naesens, Graciela Andrei, Robert Snoeck, Jan Balzarini, Sonsoles Velázquez, María-José Camarasa Journal of medicinal chemistry 2008 new
The balance between the rates of incorporation and pyrophosphorolytic removal influences the HIV-1 reverse transcriptase bypass of an abasic site with deoxy-, dideoxy-, and ribonucleotides. Bechan Sharma, Emmanuele Crespan, Giuseppe Villani, Giovanni Maga Proteins 2008 pols set
Structure of the DNA repair helicase hel308 reveals DNA binding and autoinhibitory domains. Jodi D Richards, Kenneth A Johnson, Huanting Liu, Anne-Marie McRobbie, Stephen McMahon, Muse Oke, Lester Carter, James H Naismith, Malcolm F White The Journal of biological chemistry 2008 new
The bacteriophage phi29 DNA polymerase. Margarita Salas, Luis Blanco, José María Lázaro, Miguel de Vega IUBMB Life 2008 pols set
Non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 11: structural modulations of diaryltriazines with potent anti-HIV activity. Yuan-Zhen Xiong, Fen-Er Chen, Jan Balzarini, Erik De Clercq, Christophe Pannecouque European journal of medicinal chemistry 2008 pols set
Inhibitors of HIV-1 reverse transcriptase. Tatiana Ilina, Michael A. Parniak Advances in pharmacology (San Diego, Calif.) 2008 pols set
Evolution of DNA polymerase iota structure and function in eukaryotes. Alena V Makarova, Vyacheslav Z Tarantul, Leonid V Gening Biochemistry (Mosc) 2008 new
The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases. Scott D McCulloch, Thomas A Kunkel Cell research 2008 partial results
The four-and-a-half-LIM protein 2 (FHL2) is overexpressed in gliomas and associated with oncogenic activities. Ming Li, Jide Wang, Samuel S M Ng, Chu-Yan Chan, Amy C Chen, Hong Ping Xia, David T Yew, Benjamin Chun-Yu Wong, Zhu Chen, Hsiang-Fu Kung, Marie Chia-Mi Lin Glia 2008 new
Persistent presence of postoperative circulating tumor cells is a poor prognostic factor for patients with stage I-III colorectal cancer after curative resection. Yih-Huei Uen, Chien-Yu Lu, Hsiang-Lin Tsai, Fang-Jung Yu, Ming-Yii Huang, Tian-Lu Cheng, Shiu-Ru Lin, Jaw-Yuan Wang Annals of surgical oncology 2008 new
Gene 1.7 of bacteriophage T7 confers sensitivity of phage growth to dideoxythymidine. Ngoc Quang Tran, Lisa F Rezende, Udi Qimron, Charles C Richardson, Stanley Tabor Proceedings of the National Academy of Sciences of the United States of America 2008 pols set
Use of RNAi in C. elegans. Tsuyoshi Ohkumo, Chikahide Masutani, Toshihiko Eki, Fumio Hanaoka Methods in molecular biology (Clifton, N.J.) 2008 new
Establishment of immortalized human hepatocytes by introduction of HPV16 E6/E7 and hTERT as cell sources for liver cell-based therapy. Yosuke Tsuruga, Tohru Kiyono, Michiaki Matsushita, Tomosaburo Takahashi, Hironori Kasai, Shuichiro Matsumoto, Satoru Todo Cell transplantation 2008 new
Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes. Stella A Martomo, Huseyin Saribasak, Masayuki Yokoi, Fumio Hanaoka, Patricia J Gearhart DNA repair 2008 new
The Leu22Pro tumor-associated variant of DNA polymerase beta is dRP lyase deficient. Shibani Dalal, Anna K Chikova, Joachim Jaeger, Joann B Sweasy Nucleic acids research 2008 new
Structure of PolC reveals unique DNA binding and fidelity determinants. Ronald J Evans, Douglas R Davies, James M Bullard, Jeffrey Christensen, Louis S Green, Joseph W Guiles, Janice D Pata, Wendy K Ribble, Nebojsa Janjic, Thale C Jarvis Proceedings of the National Academy of Sciences of the United States of America 2008 topics set
Activity of the small modified amino acid alpha-hydroxy glycineamide on in vitro and in vivo human immunodeficiency virus type 1 capsid assembly and infectivity. Samir Abdurahman, Akos Végvári, Masoud Youssefi, Michael Levi, Stefan Höglund, Elin Andersson, Peter Horal, Bo Svennerholm, Jan Balzarini, Anders Vahlne Antimicrobial agents and chemotherapy 2008 pols set
1,2,3-Thiadiazole thioacetanilides as a novel class of potent HIV-1 non-nucleoside reverse transcriptase inhibitors. Peng Zhan, Xinyong Liu, Yuan Cao, Yan Wang, Christophe Pannecouque, Erik De Clercq Bioorganic & medicinal chemistry letters 2008 pols set
DNA-dependent DNA polymerases. R B Kucera, NM Nichols Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2008 complete Rebecca Kucera*
Domain architecture and biochemical characterization of vertebrate Mcm10. PD Robertson, Eric M Warren, Haijiang Zhang, DB Friedman, JW Lary, JL Cole, AV Tutter, JC Walter, Ellen Fanning, Brandt F Eichman The Journal of biological chemistry 2008 topics set
Phage phi29 and Nf terminal protein-priming domain specifies the internal template nucleotide to initiate DNA replication. Elisa Longás, Laurentino Villar, José María Lázaro, Miguel de Vega, Margarita Salas Proceedings of the National Academy of Sciences of the United States of America 2008 topics set
Specific up-regulation of DNA polymerase by human papillomavirus 16. Song-Nian Liu, Wu-Yun Bai, Russell M Frye, Lin Hou, Bo Zhang Chin Med Sci J 2008 new
Inhibition of human immunodeficiency virus type 1 replication in human cells by Debio-025, a novel cyclophilin binding agent. Roger G Ptak, Philippe A Gallay, Dirk Jochmans, Andrew P Halestrap, Urs T Ruegg, Luke A Pallansch, Michael D Bobardt, Marie-Pierre P De Béthune, Johan Neyts, Erik De Clercq, Jean-Maurice Dumont, Pietro Scalfaro, Kamel Besseghir, Roland M Wenger, Brigitte Rosenwirth Antimicrobial agents and chemotherapy 2008 pols set
Design and synthesis of dual inhibitors of HIV reverse transcriptase and integrase: introducing a diketoacid functionality into delavirdine. Zhengqiang Wang, Robert Vince Bioorganic & medicinal chemistry 2008 pols set
Mutagenic and recombinagenic responses to defective DNA polymerase delta are facilitated by the Rev1 protein in pol3-t mutants of Saccharomyces cerevisiae. Erica Mito, Janet V Mokhnatkin, Molly C Steele, Victoria L Buettner, Steve S Sommer, Glenn M Manthey, Adam M Bailis Genetics 2008 topics set
Detection and distribution of rotavirus in municipal sewage treatment plants (STPs) and surface water in Beijing. Xiao Q He, Li Cheng, Wei Li, Xiang M Xie, Mei Ma, Zi J Wang Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 2008 new
Interventricular mechanical asynchrony in pulmonary arterial hypertension: left-to-right delay in peak shortening is related to right ventricular overload and left ventricular underfilling. J Tim Marcus, C Tji-Joong Gan, Jaco J M Zwanenburg, Anco Boonstra, Cor P Allaart, Marco J W Götte, Anton Vonk-Noordegraaf J Am Coll Cardiol 2008 new
Synthesis of pyrimidine and quinolone conjugates as a scaffold for dual inhibitors of HIV reverse transcriptase and integrase. Zhengqiang Wang, Robert Vince Bioorganic & medicinal chemistry letters 2008 pols set
DNA polymerases beta and lambda as potential participants of TLS during genomic DNA replication on the lagging strand. A A Shtygasheva, Ekaterina A Belousova, Nadejda I Rechkunova, Natalia A Lebedeva, Olga I Lavrik Biochemistry. Biokhimii͡a 2008 new
Investigation of the alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors as potential cAMP phosphodiesterase-4B2 inhibitors. Matthew D Cullen, York-Fong Cheung, Miles D Houslay, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman Bioorganic & medicinal chemistry letters 2008 pols set
Replication bypass of the acrolein-mediated deoxyguanine DNA-peptide cross-links by DNA polymerases of the DinB family. Irina G Minko, Kinrin Yamanaka, Ivan D Kozekov, Albena Kozekova, Chiara Indiani, Michael E O'Donnell, Qingfei Jiang, Myron F Goodman, Carmelo J Rizzo, R Stephen Lloyd Chemical research in toxicology 2008 new
Phage phi29 protein p56 prevents viral DNA replication impairment caused by uracil excision activity of uracil-DNA glycosylase. Gemma Serrano-Heras, Alicia Bravo, Margarita Salas Proceedings of the National Academy of Sciences of the United States of America 2008 pols set
Intrinsic properties of the two replicative DNA polymerases of Pyrococcus abyssi in replicating abasic sites: possible role in DNA damage tolerance? Adeline Palud, Giuseppe Villani, Stéphane L'Haridon, Joël Querellou, Jean-Paul Raffin, Ghislaine Henneke Molecular microbiology 2008 partial results
XRCC1 and DNA polymerase beta in cellular protection against cytotoxic DNA single-strand breaks. Julie K Horton, Mary Watson, Donna F Stefanick, Daniel T Shaughnessy, Jack A Taylor, Samuel H Wilson Cell research 2008 new
The Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase delta. Nives Selak, Csanád Z Bachrati, Igor V Shevelev, Tobias Dietschy, Barbara van Loon, Anette Jacob, Ulrich Hübscher, Joerg D Hoheisel, Ian D Hickson, Igor Stagljar Nucleic acids research 2008 pols set
Regulation of Saccharomyces cerevisiae DNA polymerase eta transcript and protein. Ritu Pabla, Donald Rozario, Wolfram Siede Radiat Environ Biophys 2008 pols set
Vinylogous ureas as a novel class of inhibitors of reverse transcriptase-associated ribonuclease H activity. Michaela Wendeler, Hsiu-Fang Lee, Alun Bermingham, Jennifer T Miller, Oleg Chertov, Marion K Bona, Noel S Baichoo, Maryam Ehteshami, John A Beutler, Barry R O'Keefe, Matthias Götte, Mamuka Kvaratskhelia, Stuart F J Le Grice ACS Chem Biol 2008 new
Quantum mechanics/molecular mechanics investigation of the chemical reaction in Dpo4 reveals water-dependent pathways and requirements for active site reorganization. Yazhen Wang, Tamar Schlick Journal of the American Chemical Society 2008 topics set
Structural insights on the pamoic acid and the 8 kDa domain of DNA polymerase beta complex: towards the design of higher-affinity inhibitors. Corinne Hazan, François Boudsocq, Virginie Gervais, Olivier Saurel, Marion Ciais, Christophe Cazaux, Jerzy Czaplicki, Alain Milon BMC Struct Biol 2008 new
Regulated proteolysis of DNA polymerase eta during the DNA-damage response in C. elegans. Seung-Hwan Kim, W Matthew Michael Molecular cell 2008 new
Molecular modeling and functional characterization of the monomeric primase-polymerase domain from the Sulfolobus solfataricus plasmid pIT3. S Prato, RM Vitale, P Contursi, G Lipps, M Saviano, M Rossi, S Bartolucci The FEBS journal 2008 topics set
DNA polymerase I is not required for replication of linear chromosomes in streptomyces. Tzu-Wen Huang, Carton W Chen J Bacteriol 2008 new
Epstein-Barr virus-encoded microRNA miR-BART2 down-regulates the viral DNA polymerase BALF5. Stephanie Barth, Thorsten Pfuhl, Alfredo Mamiani, Claudia Ehses, Klaus Roemer, Elisabeth Kremmer, Christoph Jäker, Julia Höck, Gunter Meister, Friedrich A Grässer Nucleic acids research 2008 new
Early upregulation of cyclooxygenase-2 in human papillomavirus type 16 and telomerase-induced immortalization of human esophageal epithelial cells. Ze-Hao Zhuang, Sai-Wah Tsao, Wen Deng, Ji-De Wang, Harry Hua-Xiang Xia, Hua He, Hui-Chen Feng, Li-Dong Wang, Qing Gu, S-K Lam, Marie Chia-Mi Lin, Hsiang-Fu Kung, Benjamin Chun-Yu Wong Journal of gastroenterology and hepatology 2008 new
Proteomic analysis of human bone marrow mesenchymal stem cells transduced with human telomerase reverse transcriptase gene during proliferation. G P Huang, Z J Pan, J P Huang, J F Yang, C J Guo, Y G Wang, Q Zheng, R Chen, Y L Xu, G Z Wang, Y M Xi, D Shen, J Jin, J F Wang Cell proliferation 2008 new
Rapidly progressive neurological deterioration in a child with Alpers syndrome exhibiting a previously unremarkable brain MRI. Nicola Brunetti-Pierri, K Selby, M O'Sullivan, G Hendson, Cavatina K Truong, Paula J Waters, L-J Wong Neuropediatrics 2008 pols set
Interaction of APE1 and other repair proteins with DNA duplexes imitating intermediates of DNA repair and replication. Nadezhda S Dyrkheeva, Svetlana N Khodyreva, Olga I Lavrik Biochemistry. Biokhimii͡a 2008 new
RNA primer handoff in bacteriophage T4 DNA replication: the role of single-stranded DNA-binding protein and polymerase accessory proteins. Scott W Nelson, Ravindra Kumar, Stephen J Benkovic The Journal of biological chemistry 2008 topics set
Pif1 helicase directs eukaryotic Okazaki fragments toward the two-nuclease cleavage pathway for primer removal. MarieL Rossi, JasonE Pike, Wensheng Wang, PeterMJ Burgers, JudithL Campbell, RobertA Bambara The Journal of biological chemistry 2008 new
Rapid purification of truncated Taq DNA polymerase Stoffel fragment by boiling lysis of bacterial expression cultures. Zhengan Yang, Yumei Ding, Yongqing Zhang, Feihu Liu Biotechnol Appl Biochem 2008 pols set
Pyranicin, a non-classical annonaceous acetogenin, is a potent inhibitor of DNA polymerase, topoisomerase and human cancer cell growth. Shunya Takahashi, Yuko Yonezawa, Akemi Kubota, Narihito Ogawa, Katsuya Maeda, Hiroyuki Koshino, Tadashi Nakata, Hiromi Yoshida, Yoshiyuki Mizushina Int J Oncol 2008 new
Altered order of substrate binding by DNA polymerase X from African Swine Fever virus. Sandeep Kumar, Marina Bakhtina, Ming-Daw Tsai Biochemistry 2008 new
2'-deoxy-4'-C-ethynyl-2-halo-adenosines active against drug-resistant human immunodeficiency virus type 1 variants. Atsushi Kawamoto, Eiichi N Kodama, Stefan G Sarafianos, Yasuko Sakagami, Satoru Kohgo, Kenji Kitano, Noriyuki Ashida, Yuko Iwai, Hiroyuki Hayakawa, Hirotomo Nakata, Hiroyuki Mitsuya, Edward Arnold, Masao Matsuoka The international journal of biochemistry & cell biology 2008 pols set
Historical perspective: Arthur Kornberg, a giant of 20th century biochemistry. IRobert Lehman Trends in biochemical sciences 2008 new
A dynamic polymerase exchange with Escherichia coli DNA polymerase IV replacing DNA polymerase III on the sliding clamp. Asako Furukohri, Myron F Goodman, Hisaji Maki The Journal of biological chemistry 2008 pols set
Biochemical evolution of DNA polymerase eta: properties of plant, human, and yeast proteins. Peter D Hoffman, Marc J Curtis, Shigenori Iwai, John B Hays Biochemistry 2008 new
Enzymatic synthesis of structure-free DNA with pseudo-complementary properties. Georges Lahoud, Victor Timoshchuk, Alexandre Lebedev, Miguel de Vega, Margarita Salas, Khalil Arar, Ya-Ming Hou, Howard Gamper Nucleic acids research 2008 topics set
Mutations in the U5 region adjacent to the primer binding site affect tRNA cleavage by human immunodeficiency virus type 1 reverse transcriptase in vivo. Jangsuk Oh, Mary Jane McWilliams, John G Julias, Stephen H Hughes Journal of virology 2008 pols set
Apparent defects in processive DNA synthesis, strand transfer, and primer elongation of Met-184 mutants of HIV-1 reverse transcriptase derive solely from a dNTP utilization defect. Lu Gao, Mark Nils Hanson, Mini Balakrishnan, Paul L Boyer, Bernard P Roques, Stephen H Hughes, Baek Kim, Robert A Bambara The Journal of biological chemistry 2008 pols set
HIV-1 reverse transcriptase connection subdomain mutations reduce template RNA degradation and enhance AZT excision. Krista A Delviks-Frankenberry, Galina N Nikolenko, Paul L Boyer, Stephen H Hughes, John M Coffin, Abhay Jere, Vinay K Pathak Proceedings of the National Academy of Sciences of the United States of America 2008 pols set
The effects of alternate polypurine tracts (PPTs) and mutations of sequences adjacent to the PPT on viral replication and cleavage specificity of the Rous sarcoma virus reverse transcriptase. Kevin W Chang, Jangsuk Oh, W Gregory Alvord, Stephen H Hughes Journal of virology 2008 new
DNA polymerase I-mediated translesion synthesis in RecA-independent DNA interstrand cross-link repair in E. coli. Laura Zietlow, Tadayoshi Bessho Biochemistry 2008 complete Tadayoshi Bessho*
Effect of dehydroaltenusin-C12 derivative, a selective DNA polymerase alpha inhibitor, on DNA replication in cultured cells. Isoko Kuriyama, Takeshi Mizuno, Keishi Fukudome, Kouji Kuramochi, Kazunori Tsubaki, Takeo Usui, Naoko Imamoto, Kengo Sakaguchi, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Molecules 2008 complete Takeshi Mizuno*
DNA polymerase delta is highly processive with proliferating cell nuclear antigen and undergoes collision release upon completing DNA. Lance D Langston, Mike E O'Donnell The Journal of biological chemistry 2008 topics set
The enhanced DNA replication fidelity of a mutant herpes simplex virus type 1 DNA polymerase is mediated by an improved nucleotide selectivity and reduced mismatch extension ability. Wang Tian, Ying T Hwang, Charles B C Hwang J Virol 2008 new
Low levels of DNA polymerase alpha induce mitotic and meiotic instability in the ribosomal DNA gene cluster of Saccharomyces cerevisiae. Anne M Casper, Piotr A Mieczkowski, Malgorzata Gawel, Thomas D Petes PLoS Genet 2008 pols set
Synthetic studies on kohamaic acids: synthesis of structurally simplified analogs of kohamaic acid A. Hirosato Takikawa, Naoki Kamatani, Kohei Nakanishi, Takuya Tashiro, Mitsuru Sasaki, Hiromi Yoshida, Yoshiyuki Mizushina Bioscience, biotechnology, and biochemistry 2008 new
A highly conserved family of inactivated archaeal B family DNA polymerases. Igor B Rogozin, Kira S Makarova, Youri I Pavlov, Eugene V Koonin Biol Direct 2008 topics set
Effects of mutations in the connection and RNase H domains of HIV-1 reverse transcriptase on drug susceptibility. Maryam Ehteshami, Matthias Götte AIDS Rev 2008 topics set
Evidence for lesion bypass by yeast replicative DNA polymerases during DNA damage. Nasim Sabouri, Jörgen Viberg, Dinesh Kumar Goyal, Erik Johansson, Andrei Chabes Nucleic acids research 2008 pols set
Ubiquitylation of proliferating cell nuclear antigen and recruitment of human DNA polymerase eta. Nana Nikolaishvili-Feinberg, G Scott Jenkins, Kathleen R Nevis, Dean P Staus, Cameron O Scarlett, Keziban Unsal-Kaçmaz, William K Kaufmann, Marila Cordeiro-Stone Biochemistry 2008 partial results
Structural insights into the generation of single-base deletions by the Y family DNA polymerase dbh. Ryan C Wilson, Janice D Pata Molecular cell 2008 topics set
Identification of a new motif required for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I (Klenow fragment): the RRRY motif is necessary for the binding of single-stranded DNA substrate and the template strand of the mismatched duplex. Pinky Kukreti, Kamalendra Singh, Amit Ketkar, Mukund J Modak The Journal of biological chemistry 2008 complete Mukund J Modak*
Formation of purine-purine mispairs by Sulfolobus solfataricus DNA polymerase IV. Lindsey DeCarlo, A S Prakasha Gowda, Zucai Suo, Thomas E Spratt Biochemistry 2008 topics set
Eutherians intrinsically run a higher risk of replication deficiency. Masaharu Takemura Bio Systems 2008 new
Exploring the role of large conformational changes in the fidelity of DNA polymerase beta. Yun Xiang, Myron F Goodman, William A Beard, Samuel H Wilson, Arieh Warshel Proteins 2008 new
Nuclear import of HSV-1 DNA polymerase processivity factor UL42 is mediated by a C-terminally located bipartite nuclear localization signal. Gualtiero Alvisi, Simone Avanzi, Daniele Musiani, Daria Camozzi, Valerio Leoni, Jennifer D Ly-Huynh, Alessandro Ripalti Biochemistry 2008 topics set
Templated mutagenesis in bacteriophage T4 involving imperfect direct or indirect sequence repeats. Gary E Schultz, John W Drake Genetics 2008 complete
Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp. Roxana E Georgescu, Olga Yurieva, Seung-Sup Kim, John Kuriyan, Xiang-Peng Kong, Mike E O'Donnell Proceedings of the National Academy of Sciences of the United States of America 2008 topics set
Mechanism of antiviral drug resistance of vaccinia virus: identification of residues in the viral DNA polymerase conferring differential resistance to antipoxvirus drugs. Don B Gammon, Robert Snoeck, Pierre Fiten, Marcela Krecmerová, Antonín Holý, Erik De Clercq, Ghislain Opdenakker, David H Evans, Graciela Andrei J Virol 2008 complete David H Evans*
Arabidopsis thaliana Y-family DNA polymerase eta catalyses translesion synthesis and interacts functionally with PCNA2. Heather J Anderson, Edward J Vonarx, Landon Pastushok, Mayu Nakagawa, Atsushi Katafuchi, Petr Grúz, Antonio Di Rubbo, Desma M Grice, Megan J Osmond, Ayako N Sakamoto, Takehiko Nohmi, Wei Xiao, Bernard A Kunz Plant J 2008 complete Bernard A Kunz*
DNA polymerase delta is preferentially recruited during homologous recombination to promote heteroduplex DNA extension. Laurent Maloisel, Francis Fabre, Serge Gangloff Molecular and cellular biology 2008 new
Mutations M184V and Y115F in HIV-1 reverse transcriptase discriminate against "nucleotide-competing reverse transcriptase inhibitors". Maryam Ehteshami, Brian J Scarth, Egor P Tchesnokov, Chandravanu Dash, Stuart F J Le Grice, Sabine Hallenberger, Dirk Jochmans, Matthias Götte The Journal of biological chemistry 2008 topics set
Transmission networks of drug resistance acquired in primary/early stage HIV infection. Bluma G Brenner, Michel Roger, Daniela D Moisi, Maureen Oliveira, Isabelle Hardy, Reuven Turgel, Hugues Charest, Jean-Pierre Routy, Mark A. Wainberg AIDS (London, England) 2008 pols set
Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding. Kristie D Goodwin, Mark A Lewis, Eric C Long, Millie M Georgiadis Proceedings of the National Academy of Sciences of the United States of America 2008 topics set
Structure and function of 2:1 DNA polymerase.DNA complexes. Kuo-Hsiang Tang, Ming-Daw Tsai J Cell Physiol 2008 new
Cidofovir diphosphate inhibits molluscum contagiosum virus DNA polymerase activity. Takahiro Watanabe, Kunihiko Tamaki J Invest Dermatol 2008 new
Low-fidelity DNA synthesis by human DNA polymerase theta. Mercedes E Arana, Masayuki Seki, Richard D Wood, Igor B Rogozin, Thomas A Kunkel Nucleic acids research 2008 partial results
Substitution of a residue contacting the triphosphate moiety of the incoming nucleotide increases the fidelity of yeast DNA polymerase zeta. Craig A Howell, Christine M Kondratick, M Todd Washington Nucleic acids research 2008 topics set
Microbial subversion of heparan sulfate proteoglycans. Ye Chen, Matthias Götte, Jianhua Liu, Pyong Woo Park Mol Cells 2008 new
Analysis of processivity of mungbean dideoxynucleotide-sensitive DNA polymerase and detection of the activity and expression of the enzyme in the meristematic and meiotic tissues and following DNA damaging agent. Sujit Roy, Swarup Roy Choudhury, Dibyendu Narayan SenGupta Arch Biochem Biophys 2008 new
Translesion synthesis across the (6-4) photoproduct and its Dewar valence isomer by the Y-family and engineered DNA polymerases. Junpei Yamamoto, David Loakes, Chikahide Masutani, Shizu Simmyo, Kumiko Urabe, Fumio Hanaoka, Philipp Holliger, Shigenori Iwai Nucleic acids symposium series (2004) 2008 pols set
Proofreading activity of DNA polymerase Pol2 mediates 3'-end processing during nonhomologous end joining in yeast. Shun-Fu Tseng, Abram Gabriel, Shu-Chun Teng PLoS Genet 2008 complete Shu-Chun Teng*
Base pair hydrogen bonds are essential for proofreading selectivity by the human mitochondrial DNA polymerase. Harold R Lee, Sandra A Helquist, Eric T Kool, Kenneth A Johnson The Journal of biological chemistry 2008 new
The epsilon subunit of DNA polymerase III Is involved in the nalidixic acid-induced SOS response in Escherichia coli. Jennifer Reineke Pohlhaus, David T Long, Erin O'Reilly, Kenneth N Kreuzer J Bacteriol 2008 complete Kenneth N Kreuzer*
Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues. Andrea Lisco, Christophe Vanpouille, Egor P Tchesnokov, Jean-Charles Grivel, Angélique Biancotto, Beda Brichacek, Julie Elliott, Emilie Fromentin, Robin Shattock, Peter Anton, Robert Gorelick, Jan Balzarini, Christopher McGuigan, Marco Derudas, Matthias Götte, Raymond F Schinazi, Leonid Margolis Cell Host Microbe 2008 partial results
Genetic analysis reveals an intrinsic property of the germinal center B cells to generate A:T mutations. Rika Ouchida, Akiko Ukai, Hiromi Mori, Kiyoko Kawamura, Martijn E T Dollé, Masatoshi Tagawa, Akemi Sakamoto, Takeshi Tokuhisa, Tadashi Yokosuka, Takashi Saito, Masayuki Yokoi, Fumio Hanaoka, Jan Vijg, Ji-Yang Wang DNA repair 2008 new
Connection domain mutations N348I and A360V in HIV-1 reverse transcriptase enhance resistance to 3'-azido-3'-deoxythymidine through both RNase H-dependent and -independent mechanisms. Maryam Ehteshami, Greg L Beilhartz, Brian J Scarth, Egor P Tchesnokov, Suzanne McCormick, Brian Wynhoven, P Richard Harrigan, Matthias Götte The Journal of biological chemistry 2008 topics set
Sensing domain and extension rate of a family B-type DNA polymerase determine the stalling at a deaminated base. Yun Jae Kim, Sun-Shin Cha, Hyun Sook Lee, Yong Gu Ryu, Seung Seob Bae, Yona Cho, Hyun-Soo Cho, Soon-Jong Kim, Suk-Tae Kwon, Jung-Hyun Lee, Sung Gyun Kang J Microbiol Biotechnol 2008 new
Entecavir for treatment of hepatitis B virus displays no in vitro mitochondrial toxicity or DNA polymerase gamma inhibition. Charles E Mazzucco, Robert K Hamatake, Richard J Colonno, Daniel J Tenney Antimicrob Agents Chemother 2008 new
Importance of hydrogen bonding for efficiency and specificity of the human mitochondrial DNA polymerase. Harold R Lee, Sandra A Helquist, Eric T Kool, Kenneth A Johnson The Journal of biological chemistry 2008 topics set
Mutational specificity of gamma-radiation-induced guanine-thymine and thymine-guanine intrastrand cross-links in mammalian cells and translesion synthesis past the guanine-thymine lesion by human DNA polymerase eta. Laureen C Colis, Paromita Raychaudhury, Ashis K Basu Biochemistry 2008 complete Ashis K Basu*
Role of DNA polymerases eta, iota and zeta in UV resistance and UV-induced mutagenesis in a human cell line. Quentin Gueranger, Anne Stary, Saïd Aoufouchi, Ahmad Faili, Alain Sarasin, Claude-Agnès Reynaud, Jean-Claude Weill DNA repair 2008 topics set
Synthesis of 3'-deoxyapionucleoside triphosphates and their incorporation into DNA by DNA polymerase. Mayumi Kataoka, Kousuke Sato, Akira Matsuda Nucleic Acids Symp Ser (Oxf) 2008 new
The N-clasp of human DNA polymerase kappa promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesions. Lei Jia, Nicholas E Geacintov, Suse Broyde Nucleic acids research 2008 pols set
Mutagenesis is elevated in male germ cells obtained from DNA polymerase-beta heterozygous mice. Diwi Allen, Damon C Herbert, C Alex McMahan, Vladimir Rotrekl, Robert W Sobol, Samuel H Wilson, Christi A Walter Biol Reprod 2008 new
Effect of oxidatively damaged DNA on the active site preorganization during nucleotide incorporation in a high fidelity polymerase from Bacillus stearothermophilus. Ravindra Venkatramani, Ravi Radhakrishnan Proteins 2008 topics set
Mechanism and dynamics of translesion DNA synthesis catalyzed by the Escherichia coli Klenow fragment. Asim Sheriff, Edward Motea, Irene Lee, Anthony J Berdis Biochemistry 2008 pols set
Kinetic investigation of the inhibitory effect of gemcitabine on DNA polymerization catalyzed by human mitochondrial DNA polymerase. Jason D Fowler, Jessica A Brown, Kenneth A Johnson, Zucai Suo The Journal of biological chemistry 2008 pols set
[Effect of nanosize delivery system for ASODN against hTERT on the expression of telomerase in the esophageal cancer EC9706 cells]. Jin Wang, Zhen-zhong Zhang, Tian-yang Zhou, Yu-qiong Liu, Hui-xiang Li Zhonghua zhong liu za zhi [Chinese journal of oncology] 2008 new
DNA polymerase eta is a limiting factor for A:T mutations in Ig genes and contributes to antibody affinity maturation. Keiji Masuda, Rika Ouchida, Masayuki Yokoi, Fumio Hanaoka, Takachika Azuma, Ji-Yang Wang Eur J Immunol 2008 new
Role of induced fit in enzyme specificity: a molecular forward/reverse switch. Kenneth A Johnson The Journal of biological chemistry 2008 new
REV1 restrains DNA polymerase zeta to ensure frame fidelity during translesion synthesis of UV photoproducts in vivo. Dávid Szüts, Adam P Marcus, Masayuki Himoto, Shigenori Iwai, Julian E Sale Nucleic acids research 2008 new
Exonuclease removal of dideoxycytidine (zalcitabine) by the human mitochondrial DNA polymerase. Jeremiah W Hanes, Kenneth A Johnson Antimicrobial agents and chemotherapy 2008 new
Nucleoside reverse transcriptase inhibitors and their phosphorylated metabolites in human immunodeficiency virus-infected human matrices. Jiaping Lai, Jun Wang, Zongwei Cai Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008 pols set
A new family of polymerases related to superfamily A DNA polymerases and T7-like DNA-dependent RNA polymerases. Lakshminarayan M Iyer, Saraswathi Abhiman, L Aravind Biol Direct 2008 topics set
Cidofovir and (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine are highly effective inhibitors of vaccinia virus DNA polymerase when incorporated into the template strand. Wendy C Magee, Kathy A Aldern, Karl Y Hostetler, David H Evans Antimicrob Agents Chemother 2008 complete David H Evans*
Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase gamma replication fidelity. Zachary F Pursell, J Tyson McDonald, Christopher K Mathews, Thomas A Kunkel Nucleic acids research 2008 new
A method to assay inhibitors of DNA polymerase IIIC activity. Michelle M Butler, George E Wright Methods Mol Med 2008 new
Inhibition of HSV-1 replication and HSV DNA polymerase by the chloroxoquinolinic ribonucleoside 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid and its aglycone. Thiago Moreno L Souza, Maria Cecilia Bastos V De Souza, Vitor F Ferreira, Carla Veronica B Santos Canuto, Isakelly Pereira Marques, Carlos Frederico L Fontes, Izabel C P P Frugulhetti Antiviral Res 2008 new
[Effects of human telomerase reverse transcriptase promoter and survivin promoter in targeted tumor gene therapy]. Yongqing Zhang, Hong Ma, Shi-Lian Liu, Yan-Xin Liu, De-Xian Zheng Zhonghua yi xue za zhi 2008 new
DNA polymerase gamma inhibition by vitamin K3 induces mitochondria-mediated cytotoxicity in human cancer cells. Ryohei Sasaki, Yoko Suzuki, Yuko Yonezawa, Yosuke Ota, Yoshiaki Okamoto, Yusuke Demizu, Peng Huang, Hiromi Yoshida, Kazuro Sugimura, Yoshiyuki Mizushina Cancer Sci 2008 new
Novel evidences for a tumor suppressor role of Rev3, the catalytic subunit of Pol zeta. J-M Brondello, Marie-Jeanne Pillaire, C Rodriguez, P-A Gourraud, Janick Selves, Christophe Cazaux, J Piette Oncogene 2008 topics set
Biochemical studies with DNA polymerase beta and DNA polymerase beta-PAK of Trypanosoma cruzi suggest the involvement of these proteins in mitochondrial DNA maintenance. Débora de Oliveira Lopes, Bruno Luiz Fonseca Schamber-Reis, Carlos Gustavo Regis-da-Silva, Matheus Andrade Rajão, Wanderson Duarte DaRocha, Andréa Mara Macedo, Glória Regina Franco, Sheila Cristina Nardelli, Sérgio Schenkman, Jean-Sébastien Hoffmann, Christophe Cazaux, Sérgio Danilo Junho Pena, Santuza Maria Ribeiro Teixeira, Carlos Renato Machado DNA repair 2008 complete Carlos Renato Machado*
Interplay between DNA polymerase and proliferating cell nuclear antigen switches off base excision repair of uracil and hypoxanthine during replication in archaea. Kieran Emptage, Rory O'Neill, Alexandra Solovyova, Bernard A Connolly Journal of molecular biology 2008 new
DNA polymerase beta fidelity: halomethylene-modified leaving groups in pre-steady-state kinetic analysis reveal differences at the chemical transition state. Christopher A Sucato, Thomas G Upton, Boris A Kashemirov, Jorge Osuna, Keriann Oertell, William A Beard, Samuel H Wilson, Jan Florián, Arieh Warshel, Charles E McKenna, Myron F Goodman Biochemistry 2008 new
Contrasting drug resistance phenotypes resulting from cytomegalovirus DNA polymerase mutations at the same exonuclease locus. Sunwen Chou, Gail Marousek, Shaobing Li, Adriana Weinberg J Clin Virol 2008 new
Mutation frequencies and spectra in DNA polymerase eta-deficient mice. Rita A Busuttil, Qingcong Lin, Peter J Stambrook, Raju Kucherlapati, Jan Vijg Cancer research 2008 new
Efficient inhibition of human cytomegalovirus DNA polymerase expression by small hairpin RNA in vitro. Ran Tao, Miaofeng Hu, Qunjun Duan, Shiqiang Shang Curr Microbiol 2008 pols set
A tandem repeat of human telomerase reverse transcriptase (hTERT) and risk of breast cancer development and metastasis in Chinese women. Yan Wang, Zhibin Hu, Jie Liang, Zhengqiang Wang, Jinhai Tang, Shui Wang, Xuechen Wang, Jianwei Qin, Xinru Wang, Hongbing Shen Carcinogenesis 2008 new
[Preliminary study of DNA polymerase beta gene silencing by small interfering RNA in human gastric cancer BGC-823 cells]. Guo-qiang Zhao, Lei Wang, Zi-ming Dong Zhonghua Zhong Liu Za Zhi 2008 new
High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: strategic flexibility explains potency against resistance mutations. Kalyan Das, Joseph David Bauman, Arthur D Clark, Yulia Volovik Frenkel, Paul J Lewi, Aaron J Shatkin, Stephen H Hughes, Edward Arnold Proceedings of the National Academy of Sciences of the United States of America 2008 partial results
The human cytomegalovirus UL44 C clamp wraps around DNA. Gloria Komazin-Meredith, Robert J Petrella, Webster L Santos, David J Filman, James M Hogle, Gregory L Verdine, Martin Karplus, Donald M Coen Structure (London, England : 1993) 2008 pols set
Two-dimensional infrared spectra reveal relaxation of the nonnucleoside inhibitor TMC278 complexed with HIV-1 reverse transcriptase. Chong Fang, Joseph David Bauman, Kalyan Das, Amanda Remorino, Edward Arnold, Robin M Hochstrasser Proceedings of the National Academy of Sciences of the United States of America 2008 pols set
Hopping of a processivity factor on DNA revealed by single-molecule assays of diffusion. Gloria Komazin-Meredith, Rossen Mirchev, David E Golan, Antoine M van Oijen, Donald M Coen Proceedings of the National Academy of Sciences of the United States of America 2008 new
Characterization of plant XRCC1 and its interaction with proliferating cell nuclear antigen. Yukinobu Uchiyama, Yuko Suzuki, Kengo Sakaguchi Planta 2008 new
Structure of a sliding clamp on DNA. Roxana E Georgescu, Seung-Sup Kim, Olga Yurieva, John Kuriyan, Xiang-Peng Kong, Mike E O'Donnell Cell 2008 topics set
Dividing the workload at a eukaryotic replication fork. Thomas A Kunkel, Peter M J Burgers Trends Cell Biol 2008 new
Inhibition of herpes simplex virus type 1 by small interfering RNA. Y Q Zhang, W Lai, H Li, G Li Clinical and experimental dermatology 2008 new
Inhibition of tubulin polymerization by select alkenyldiarylmethanes. Matthew D Cullen, Taradas Sarkar, Ernest Hamel, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman Bioorganic & medicinal chemistry letters 2008 new
Synthesis and anti-HIV evaluation of novel 1,3-disubstituted thieno[3,2-c][1,2,6]thiadiazin-4(3H)-one 2,2-dioxides(TTDDs). Yongqiang Lin, Xinyong Liu, Renzhang Yan, Jinming Li, Christophe Pannecouque, Myriam Witvrouw, Erik De Clercq Bioorganic & medicinal chemistry 2008 new
Insertion of dNTPs opposite the 1,N2-propanodeoxyguanosine adduct by Sulfolobus solfataricus P2 DNA polymerase IV. Yazhen Wang, Sarah K Musser, Sam Saleh, Lawrence J Marnett, Martin Egli, Michael P Stone Biochemistry 2008 topics set
Use of 2-aminopurine fluorescence to study the role of the beta hairpin in the proofreading pathway catalyzed by the phage T4 and RB69 DNA polymerases. Usharani Subuddhi, Matthew Hogg, Linda J Reha-Krantz Biochemistry 2008 complete
The positively charged surface of herpes simplex virus UL42 mediates DNA binding. Gloria Komazin-Meredith, Webster L Santos, David J Filman, James M Hogle, Gregory L Verdine, Donald M Coen The Journal of biological chemistry 2008 new
Kinetic analysis of translesion synthesis opposite bulky N2- and O6-alkylguanine DNA adducts by human DNA polymerase REV1. Jeong-Yun Choi, F Peter Guengerich The Journal of biological chemistry 2008 pols set
Assessment of global left ventricular functional parameters: analysis of every second short-axis Magnetic Resonance Imaging slices is as accurate as analysis of consecutive slices. Daniel D Lubbers, Tineke P Willems, Pieter A van der Vleuten, Jelle Overbosch, Marco J W Götte, Dirk J van Veldhuisen, Matthijs Oudkerk Int J Cardiovasc Imaging 2008 new
Lessons from 50 years of SOS DNA-damage-induced mutagenesis. Katharina Schlacher, Myron F Goodman Nature reviews. Molecular cell biology 2007 new
Mutations in the ubiquitin binding UBZ motif of DNA polymerase eta do not impair its function in translesion synthesis during replication. Narottam Acharya, Amrita Brahma, Lajos Haracska, Louise Prakash, Satya Prakash Molecular and cellular biology 2007 topics set
Optimization of non-natural nucleotides for selective incorporation opposite damaged DNA. Diana Vineyard, Xuemei Zhang, Alison Donnelly, Irene Lee, Anthony J Berdis Org Biomol Chem 2007 topics set
Interaction of 2'-deoxyguanosine triphosphate analogue inhibitors of HIV reverse transcriptase with human mitochondrial DNA polymerase gamma. Adrian S Ray, Joy Y Feng, Eisuke Murakami, Chung K Chu, Raymond F Schinazi, Karen S Anderson Antivir Chem Chemother 2007 new
Decreased PARP-1 levels accelerate embryonic lethality but attenuate neuronal apoptosis in DNA polymerase beta-deficient mice. Noriyuki Sugo, Naoko Niimi, Yasuaki Aratani, Mitsuko Masutani, Hiroshi Suzuki, Hideki Koyama Biochem Biophys Res Commun 2007 new
One-step purification of Taq DNA polymerase using nucleotide-mimetic affinity chromatography. Sotirios Melissis, Nikolaos E Labrou, Yannis D Clonis Biotechnol J 2007 pols set
Down-regulation of DNA polymerase beta accompanies somatic hypermutation in human BL2 cell lines. Vladimir P Poltoratsky, Rajendra Prasad, Julie K Horton, Samuel H Wilson DNA repair 2007 new
Methylation of DNA polymerase beta by protein arginine methyltransferase 1 regulates its binding to proliferating cell nuclear antigen. Nazim El-Andaloussi, Taras Valovka, Magali Toueille, Paul O Hassa, Peter Gehrig, Marcela Covic, Ulrich Hübscher, Michael O Hottiger FASEB J 2007 new
40 years with bacteriophage ø29. Margarita Salas Annual review of microbiology 2007 new
Mutator alleles of yeast DNA polymerase zeta. Ayako N Sakamoto, Jana E Stone, Grace E Kissling, Scott D McCulloch, Youri I Pavlov, Thomas A Kunkel DNA repair 2007 new
Coordination of steps in single-nucleotide base excision repair mediated by apurinic/apyrimidinic endonuclease 1 and DNA polymerase beta. Yuan Liu, Rajendra Prasad, William A Beard, Padmini S Kedar, Esther W Hou, David D Shock, Samuel H Wilson The Journal of biological chemistry 2007 new
Solution structure of polymerase mu's BRCT Domain reveals an element essential for its role in nonhomologous end joining. Eugene F DeRose, Michael W Clarkson, Steven A Gilmore, Cristina J Galban, Ashutosh Tripathy, Jody M Havener, Geoffrey A Mueller, Dale A Ramsden, Robert E London, Andrew L Lee Biochemistry 2007 topics set
The nucleoside analogs 4'C-methyl thymidine and 4'C-ethyl thymidine block DNA synthesis by wild-type HIV-1 RT and excision proficient NRTI resistant RT variants. Paul L Boyer, John G Julias, Zandrea Ambrose, Maqbool A Siddiqui, Victor E Marquez, Stephen H Hughes Journal of molecular biology 2007 topics set
Reducing DNA polymerase alpha in the absence of Drosophila ATR leads to P53-dependent apoptosis and developmental defects. Jeannine R LaRocque, Diana L Dougherty, Sumreen K Hussain, Jeff Sekelsky Genetics 2007 new
Dimerization of the Klenow fragment of Escherichia coli DNA polymerase I is linked to its mode of DNA binding. Michael F Bailey, Edwin J C Van der Schans, David P Millar Biochemistry 2007 pols set
Mechanism of template-independent nucleotide incorporation catalyzed by a template-dependent DNA polymerase. Kevin A Fiala, Jessica A Brown, Hong Ling, Ajay K Kshetry, Jun Zhang, John-Stephen Taylor, Wei Wen Yang, Zucai Suo Journal of molecular biology 2007 topics set
Error-free bypass of 2-hydroxyadenine by human DNA polymerase lambda with Proliferating Cell Nuclear Antigen and Replication Protein A in different sequence contexts. Emmanuele Crespan, Ulrich Hübscher, Giovanni Maga Nucleic acids research 2007 pols set
Determinants of nevirapine hypersensitivity and its effect on the association between hepatitis C status and mortality in antiretroviral drug-naive HIV-positive patients. Elizabeth J Phillips, Sonia Gutiérrez, Natalie Jahnke, Benita Yip, Viviane Dias Lima, Robert S Hogg, P Richard Harrigan, Julio S G Montaner Aids 2007 new
Nitroimidazoles. V. Synthesis and anti-HIV evaluation of new 5-substituted piperazinyl-4-nitroimidazole derivatives. Yaseen A Al-Soud, Najim A Al-Masoudi, Hamed Gh Hassan, Erik De Clercq, Christophe Pannecouque Acta pharmaceutica (Zagreb, Croatia) 2007 new
Molecular modeling benzo[a]pyrene N2-dG adducts in the two overlapping active sites of the Y-family DNA polymerase Dpo4. Sushil Chandani, Edward L Loechler J Mol Graph Model 2007 topics set
An efficient method for the construction of functionalized DNA bearing amino acid groups through cross-coupling reactions of nucleoside triphosphates followed by primer extension or PCR. Petr Capek, Hana Cahová, Radek Pohl, Michal Hocek, Christian Gloeckner, Andreas Marx Chemistry (Weinheim an der Bergstrasse, Germany) 2007 new
Increased single-nucleotide discrimination in allele-specific polymerase chain reactions through primer probes bearing nucleobase and 2'-deoxyribose modifications. Ramon Kranaster, Andreas Marx Chemistry (Weinheim an der Bergstrasse, Germany) 2007 new
Increased single nucleotide discrimination in arrayed primer elongation by 4'C-modified primer probes. Jens Gaster, Gopinath Rangam, Andreas Marx Chemical communications (Cambridge, England) 2007 new
Single-turnover kinetic analysis of the mutagenic potential of 8-oxo-7,8-dihydro-2'-deoxyguanosine during gap-filling synthesis catalyzed by human DNA polymerases lambda and beta. Jessica A Brown, Wade W Duym, Jason D Fowler, Zucai Suo Journal of molecular biology 2007 pols set
Dynamics of human replication factors in the elongation phase of DNA replication. Yuji Masuda, Miki Suzuki, Jinlian Piao, Yongqing Gu, Toshiki Tsurimoto, Kenji Kamiya Nucleic acids research 2007 new
Evolution of a novel 5-amino-acid insertion in the beta3-beta4 loop of HIV-1 reverse transcriptase. Marleen C D G Huigen, Loek de Graaf, Dirk Eggink, Rob Schuurman, Viktor Müller, Anna Stamp, David K Stammers, Charles A B Boucher, Monique Nijhuis Virology 2007 topics set
Human base excision repair complex is physically associated to DNA replication and cell cycle regulatory proteins. Eleonora Parlanti, Giada A Locatelli, Giovanni Maga, Eugenia Dogliotti Nucleic acids research 2007 new
Continued improvement in survival among HIV-infected individuals with newer forms of highly active antiretroviral therapy. Viviane Dias Lima, Robert S Hogg, P Richard Harrigan, David Moore, Benita Yip, Evan Wood, Julio S G Montaner Aids 2007 new
DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes. Keiji Masuda, Rika Ouchida, Masaki Hikida, Tomohiro Kurosaki, Masayuki Yokoi, Chikahide Masutani, Masayuki Seki, Richard D Wood, Fumio Hanaoka, Jiyang O-Wang The Journal of biological chemistry 2007 new
Rad54 dissociates homologous recombination intermediates by branch migration. Dmitry V Bugreev, Fumio Hanaoka, Alexander V Mazin Nature structural & molecular biology 2007 new
Hypersensitivity phenotypes associated with genetic and synthetic inhibitor-induced base excision repair deficiency. Julie K Horton, Samuel H Wilson DNA repair 2007 new
Interplay between DNA polymerases beta and lambda in repair of oxidation DNA damage in chicken DT40 cells. Keizo Tano, Jun Nakamura, Kenjiro Asagoshi, Hiroshi Arakawa, Eiichiro Sonoda, Elena K Braithwaite, Rajendra Prasad, Jean-Marie Buerstedde, Shunichi Takeda, Masami Watanabe, Samuel H Wilson DNA repair 2007 new
Different structural states in oligonucleosomes are required for early versus late steps of base excision repair. Shima Nakanishi, Rajendra Prasad, Samuel H Wilson, Michael J Smerdon Nucleic acids research 2007 new
A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol. Pierre Aller, Mark A Rould, Matthew Hogg, Susan S Wallace, Sylvie Doublié Proceedings of the National Academy of Sciences of the United States of America 2007 topics set
UmuD and RecA directly modulate the mutagenic potential of the Y family DNA polymerase DinB. Veronica G Godoy, Daniel F Jarosz, Sharotka M Simon, Alexej Abyzov, Valentin A Ilyin, Graham C Walker Molecular cell 2007 new
Loop II of DNA polymerase beta is important for polymerization activity and fidelity. George C Lin, Joachim Jaeger, Joann B Sweasy Nucleic acids research 2007 topics set
Herpes simplex virus mutants with multiple substitutions affecting DNA binding of UL42 are impaired for viral replication and DNA synthesis. Changying Jiang, Ying T Hwang, Guangliang Wang, John C W Randell, Donald M Coen, Charles B C Hwang Journal of virology 2007 new
Multiple functions of DNA polymerases. Miguel Garcia-Diaz, Katarzyna Bebenek Critical reviews in plant sciences 2007 new
2-Hydroxy-2'-deoxyadenosine 5'-triphosphate enhances A.T --> C.G mutations caused by 8-hydroxy-2'-deoxyguanosine 5'-triphosphate by suppressing its degradation upon replication in a HeLa extract. Kazuya Satou, Hironori Kasai, Chikahide Masutani, Fumio Hanaoka, Hideyoshi Harashima, Hiroyuki Kamiya Biochemistry 2007 new
Directed DNA polymerase evolution: effects of mutations in motif C on the mismatch-extension selectivity of thermus aquaticus DNA polymerase. Michael Strerath, Christian Gloeckner, Dan Liu, Andreas Schnur, Andreas Marx Chembiochem 2007 topics set
Stimulation of NEIL2-mediated oxidized base excision repair via YB-1 interaction during oxidative stress. Soumita Das, Ranajoy Chattopadhyay, Kishor K Bhakat, Istvan Boldogh, Kimitoshi Kohno, Rajendra Prasad, Samuel H Wilson, Tapas K Hazra The Journal of biological chemistry 2007 new
Proteomic analysis of p16ink4a-binding proteins. Elielson Souza-Rodrígues, Josep M Estanyol, Erica Friedrich-Heineken, Eva Olmedo, Jorge Vera, Nuria Canela, Sonia Brun, Neus Agell, Ulrich Hübscher, Oriol Bachs, Montserrat Jaumot Proteomics 2007 new
Binding parameters and thermodynamics of the interaction of the human cytomegalovirus DNA polymerase accessory protein, UL44, with DNA: implications for the processivity mechanism. Arianna Loregian, Elisa Sinigalia, Beatrice Mercorelli, Giorgio Palù, Donald M Coen Nucleic acids research 2007 pols set
Transmission of drug-resistant HIV-1 from an infected individual to a caregiver. Chanson J Brumme, P Richard Harrigan, Emma C Preston, Winnie W Y Dong, Brian Wynhoven, Carol Murphy, Julio S G Montaner Antivir Ther 2007 new
Expression of human telomerase reverse transcriptase (hTERT) protein is significantly associated with the progression, recurrence and prognosis of oral squamous cell carcinoma in Taiwan. Huang-Hsu Chen, Chuan-Hang Yu, Jeng-Tzung Wang, Bu-Yuan Liu, Yi-Ping Wang, Andy Sun, Tung-Chieh Tsai, Chun-Pin Chiang Oral oncology 2007 new
Incorporation of human immunodeficiency virus type 1 reverse transcriptase into virus-like particles. Wei-Hao Liao, Kuo-Jung Huang, Yu-Fen Chang, Shiu-Mei Wang, Ying-Tzu Tseng, Chien-Cheng Chiang, Jaang-Jiun Wang, Chin-Tien Wang Journal of virology 2007 pols set
[Evolutionary characterization of HA1 of influenza H1N1 hemagglutinin gene surveyed in 1981-2005 in China]. Jia-Huai Zhang, Hong Xu, Yongqing Zhang, Xiang Zhao, Jun-Feng Guo, Yu Lan, Yue-Long Shu Bing du xue bao = Chinese journal of virology / [bian ji, Bing du xue bao bian ji wei yuan hui] 2007 new
Discovery of non-nucleoside inhibitors of HIV-1 reverse transcriptase competing with the nucleotide substrate. Giovanni Maga, Marco Radi, Samantha Zanoli, Fabrizio Manetti, Reynel Cancio, Ulrich Hübscher, Silvio Spadari, Chiara Falciani, Montserrat Terrazas, Jaume Vilarrasa, Maurizio Botta Angewandte Chemie (International ed. in English) 2007 pols set
Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains. Maria Letizia Barreca, Angela Rao, Laura De Luca, Nunzio Iraci, Anna-Maria Monforte, Giovanni Maga, Erik De Clercq, Christophe Pannecouque, Jan Balzarini, Alba Chimirri Bioorganic & medicinal chemistry letters 2007 pols set
Construction of saccharide-modified DNAs by DNA polymerase. Masayuki Matsui, Yoshitaka Nishiyama, Shin-ichi Ueji, Yasuhito Ebara Bioorganic & medicinal chemistry letters 2007 new
7-Oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamides: synthesis and biological activity of a new class of highly potent inhibitors of human cytomegalovirus DNA polymerase. Scott D Larsen, Zhijun Zhang, Brian A DiPaolo, Peter R Manninen, Douglas C Rohrer, Michael J Hageman, Todd A Hopkins, Mary L Knechtel, Nancee L Oien, Bob D Rush, Francis J Schwende, Kevin J Stefanski, Janet L Wieber, Karen F Wilkinson, Kathyrn M Zamora, Michael W Wathen, Roger J Brideau Bioorganic & medicinal chemistry letters 2007 pols set
Ornithine transport via cationic amino acid transporter-1 is involved in ornithine cytotoxicity in retinal pigment epithelial cells. Shiho Kaneko, Akira Ando, Emiko Okuda-Ashitaka, Masahide Maeda, Kyoji Furuta, Motoshi Suzuki, Miyo Matsumura, Seiji Ito Investigative ophthalmology & visual science 2007 new
Efficient and erroneous incorporation of oxidized DNA precursors by human DNA polymerase eta. Masatomi Shimizu, Petr Grúz, Hiroyuki Kamiya, Chikahide Masutani, Yan Xu, Yukio Usui, Hiroshi Sugiyama, Hideyoshi Harashima, Fumio Hanaoka, Takehiko Nohmi Biochemistry 2007 pols set
Quantitative measurement of telomerase reverse transcriptase, thyroglobulin and thyroid transcription factor 1 mRNAs in anaplastic thyroid carcinoma tissues and cell lines. Toru Takano, Yasuhiro Ito, Fumio Matsuzuka, Akihiro Miya, Kaoru Kobayashi, Hiroshi Yoshida, Akira Miyauchi Oncology reports 2007 new
Inefficient proofreading and biased error rates during inaccurate DNA synthesis by a mutant derivative of Saccharomyces cerevisiae DNA polymerase delta. Stephanie A Nick McElhinny, Carrie M W Stith, Peter M J Burgers, Thomas A Kunkel The Journal of biological chemistry 2007 topics set
Species-specific, P450- and sulfotransferase-mediated novel ring contraction of a naphthyridine-N-oxide compound in cynomolgus monkey. J Scott Daniels, Robert Espina, Kevin Cao, Haodan Yuan, Jianrong Lin, Sharon Diamond, Barry Johnson, James Rodgers, Shimoga Prakash, Steve Unger, David Christ, Gerald Miwa, Liang-Shang Gan, Abdul Mutlib Chemical research in toxicology 2007 pols set
Novel antiproliferative analogs of the Taq DNA polymerase inhibitor catalpol. Carlos Rodolfo Pungitore, Leticia G León, Celina García, Víctor S Martín, Carlos E Tonn, José M Padrón Bioorganic & medicinal chemistry letters 2007 pols set
Novel non-nucleoside human cytomegalovirus inhibitors based upon TSAO nucleoside derivatives: structure-activity relationships. Sonia de Castro, Graziela Andrei, Robert Snoeck, Jan Balzarini, María-José Camarasa, Sonsoles Velázquez Nucleosides, nucleotides & nucleic acids 2007 pols set
Synthesis and anti-HIV studies of 2-adamantyl-substituted thiazolidin-4-ones. Jan Balzarini, Barbara Orzeszko, Jan K Maurin, Andrzej Orzeszko European journal of medicinal chemistry 2007 pols set
Synthesis and anti-HIV activity of new metabolically stable alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors incorporating N-methoxy imidoyl halide and 1,2,4-oxadiazole systems. Takeshi Sakamoto, Matthew D Cullen, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman Journal of medicinal chemistry 2007 pols set
Slow-, tight-binding HIV-1 reverse transcriptase non-nucleoside inhibitors highly active against drug-resistant mutants. Reynel Cancio, Antonello Mai, Dante Rotili, Marino Artico, Gianluca Sbardella, Imma Clotet-Codina, José A Esté, Emmanuele Crespan, Samantha Zanoli, Ulrich Hübscher, Silvio Spadari, Giovanni Maga ChemMedChem 2007 pols set
N2-benzyloxycarbonylguan-9-yl acetic acid derivatives as HIV-1 reverse transcriptase non-nucleoside inhibitors with decreased loss of potency against common drug-resistance mutations. Kassim F Adebambo, Samantha Zanoli, Michael G Thomas, Reynel Cancio, Nicola M Howarth, Giovanni Maga ChemMedChem 2007 pols set
NtPolI-like1 and NtPolI-like2, bacterial DNA polymerase I homologs isolated from BY-2 cultured tobacco cells, encode DNA polymerases engaged in DNA replication in both plastids and mitochondria. Yuriko Ono, Atsushi Sakai, Katsuaki Takechi, Susumu Takio, Mari Takusagawa, Hiroyoshi Takano Plant Cell Physiol 2007 new
Efficient silencing of the gene coding for the epsilon subunit of DNA polymerase III in Escherichia coli is triggered by antisense RNAs featuring stability in vivo. Alessandra Stefan, Martin Tabler, Alejandro Hochkoeppler FEMS Microbiol Lett 2007 complete Alejandro Hochkoeppler*
Anti-HIV drugs. Erik De Clercq Verhandelingen - Koninklijke Academie voor Geneeskunde van België 2007 pols set
Selective inhibition of porcine endogenous retrovirus replication in human cells by acyclic nucleoside phosphonates. Minyi Shi, Xin Wang, Erik De Clercq, Sonshin Takao, Masanori Baba Antimicrobial agents and chemotherapy 2007 new
Synthesis and evaluation of 2-(2,6-dihalophenyl)-3-pyrimidinyl-1,3-thiazolidin-4-one analogues as anti-HIV-1 agents. Ravindra K Rawal, Rajkamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq Bioorganic & medicinal chemistry 2007 pols set
Aprataxin, causative gene product for EAOH/AOA1, repairs DNA single-strand breaks with damaged 3'-phosphate and 3'-phosphoglycolate ends. Tomosaburo Takahashi, Masayoshi Tada, Shuichi Igarashi, Akihide Koyama, Hidetoshi Date, Akio Yokoseki, Atsushi Shiga, Yutaka Yoshida, Shoji Tsuji, Masatoyo Nishizawa, Osamu Onodera Nucleic acids research 2007 new
Mitochondrial DNA polymerase gamma variants in idiopathic sporadic Parkinson disease. Petri T Luoma, J Eerola, Sofia Ahola, Anna H Hakonen, O Hellström, K T Kivistö, P J Tienari, Anu Suomalainen Neurology 2007 pols set
Synthesis and anti-HIV-1 activity evaluation of 5-alkyl-2-alkylthio-6-(arylcarbonyl or alpha-cyanoarylmethyl)-3,4-dihydropyrimidin-4(3H)-ones as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. Lei Ji, Fen-Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Journal of medicinal chemistry 2007 pols set
Variations in reverse transcriptase and RNase H domain mutations in human immunodeficiency virus type 1 clinical isolates are associated with divergent phenotypic resistance to zidovudine. Michel L Ntemgwa, Mark A. Wainberg, Maureen Oliveira, Daniela D Moisi, Richard G Lalonde, Valeria Micheli, Bluma G Brenner Antimicrobial agents and chemotherapy 2007 new
Kinetics of inhibition of HIV type 1 reverse transcriptase-bearing NRTI-associated mutations by apricitabine triphosphate. Fernando A Frankel, Dimitrios Coutsinos, Hongtao Xu, Mark A. Wainberg Antiviral chemistry & chemotherapy 2007 pols set
Genotypic analysis of the protease and reverse transcriptase of HIV type 1 isolates from recently infected injecting drug users in western China. Lingjie Liao, Hui Xing, Xincang Li, Yuhua Ruan, Yongqing Zhang, Guangming Qin, Yiming Shao AIDS research and human retroviruses 2007 pols set
MutS deficiency and activity of the error-prone DNA polymerase IV are crucial for determining mucA as the main target for mucoid conversion in Pseudomonas aeruginosa. Alejandro J Moyano, Adela M Luján, Carlos E Argaraña, Andrea M Smania Molecular microbiology 2007 pols set
Chemical biology of DNA polymerases: from selectivity to new functions. Andreas Marx, Daniel Summerer, Katharina B M Sauter, Christian Gloeckner, Nicolas Z Rudinger Nucleic acids symposium series (2004) 2007 new
A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment. Jacob Bauer, Guangxin Xing, Haruhiko Yagi, Jane M Sayer, Donald M Jerina, Hong Ling Proceedings of the National Academy of Sciences of the United States of America 2007 topics set
Investigating the "steric gate" of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase by targeted insertion of unnatural amino acids. George J Klarmann, Brian M Eisenhauer, Yongqing Zhang, Matthias Gotte, Janice D Pata, Deb K Chatterjee, Sidney M Hecht, Stuart F J Le Grice Biochemistry 2007 pols set
Should we include connection domain mutations of HIV-1 reverse transcriptase in HIV resistance testing. Matthias Götte PLoS medicine 2007 pols set
Immortalization of swine umbilical vein endothelial cells with human telomerase reverse transcriptase. Hai Xia Hong, Yan Ming Zhang, Hao Xu, Zheng Yuan Su, Pei Sun Molecules and cells 2007 new
Effect and mechanism of beta-L-D4A on DNA polymerase alpha. Yan Li, Ju-Sheng Lin, Ying-Hui Zhang, Xiao-Yan Wang, Ying Chang, Xing-Xing He World journal of gastroenterology : WJG 2007 new
Multiple oxidative phosphorylation deficiencies in severe childhood multi-system disorders due to polymerase gamma (POLG1) mutations. Maaike C de Vries, Richard J Rodenburg, Eva Morava, Edwin P M van Kaauwen, Henk ter Laak, Reinier A Mullaart, Irina N Snoeck, Peter M van Hasselt, Peter Harding, Lambert P W van den Heuvel, Jan A M Smeitink European journal of pediatrics 2007 pols set
Activity against human immunodeficiency virus type 1, intracellular metabolism, and effects on human DNA polymerases of 4'-ethynyl-2-fluoro-2'-deoxyadenosine. Hirotomo Nakata, Masayuki Amano, Yasuhiro Koh, Eiichi N Kodama, Guangwei Yang, Christopher M Bailey, Satoru Kohgo, Hiroyuki Hayakawa, Masao Matsuoka, Karen S Anderson, Yung-Chi Cheng, Hiroyuki Mitsuya Antimicrob Agents Chemother 2007 pols set
Mutation of the linker region of the polymerase gamma-1 (POLG1) gene associated with progressive external ophthalmoplegia and Parkinsonism. Gavin Hudson, Andrew M Schaefer, Robert W Taylor, Watcharee Tiangyou, Andrew Gibson, Graham Venables, Philip Griffiths, David J Burn, Douglass M Turnbull, Patrick F Chinnery Archives of neurology 2007 pols set
Effects of accessory proteins on the bypass of a cis-syn thymine-thymine dimer by Saccharomyces cerevisiae DNA polymerase eta. Scott D McCulloch, Adam Wood, Parie Garg, Peter M J Burgers, Thomas A Kunkel Biochemistry 2007 pols set
Novel mutation of human DNA polymerase gamma associated with mitochondrial toxicity induced by anti-HIV treatment. Hikaru Yamanaka, Hiroyuki Gatanaga, Pope Kosalaraksa, Saori Matsuoka-Aizawa, Tomonori Takahashi, Seisuke Kimura, Shinichi Oka J Infect Dis 2007 pols set
Decreased mtDNA, oxidative stress, cardiomyopathy, and death from transgenic cardiac targeted human mutant polymerase gamma. William Lewis, Brian J Day, James J Kohler, Seyed H Hosseini, Sherine S L Chan, Elgin C Green, Chad P Haase, Erin S Keebaugh, Robert Long, Tomika Ludaway, Rodney Russ, Jeffrey Steltzer, Nina Tioleco, Robert Santoianni, William C Copeland Laboratory investigation; a journal of technical methods and pathology 2007 pols set
High-level production of a functional recombinant hepatitis B virus polymerase in insect cells with a baculovirus expression system. Xiaoyan Wang, Linlin Gao, Fei Deng, Yongqing Zhang, Yan Li, Jusheng Lin Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2007 new
MELAS associated with mutations in the POLG1 gene. M Deschauer, S Tennant, A Rokicka, L He, T Kraya, Douglass M Turnbull, S Zierz, Robert W Taylor Neurology 2007 pols set
Human influenza A virus (H5N1) detection by a novel multiplex PCR typing method. Shumei Zou, Jian Han, Leying Wen, Yan Liu, Kassi Cronin, Shanjuan H Lum, Lu Gao, Jie Dong, Yongqing Zhang, Yuanji Guo, Yuelong Shu Journal of clinical microbiology 2007 new
DNA polymerase beta null mouse embryonic fibroblasts harbor a homozygous null mutation in DNA polymerase iota. Robert W Sobol DNA repair 2007 complete Robert W Sobol*
Role for DNA polymerase beta in response to ionizing radiation. Christie Vermeulen, Manon Verwijs-Janssen, Patricia Cramers, Adrian C Begg, Conchita Vens DNA repair 2007 new
Human DNA polymerase lambda is a proficient extender of primer ends paired to 7,8-dihydro-8-oxoguanine. Angel J Picher, Luis Blanco DNA repair 2007 pols set
Ischemic preconditioning induces XRCC1, DNA polymerase-beta, and DNA ligase III and correlates with enhanced base excision repair. Ning Li, Hao Wu, Sufang Yang, Dexi Chen DNA repair 2007 new
Bcl2 impedes DNA mismatch repair by directly regulating the hMSH2-hMSH6 heterodimeric complex. Yongzhong Hou, Fengqin Gao, Qinhong Wang, Jinfeng Zhao, Tammy Flagg, Yongqing Zhang, Xingming Deng The Journal of biological chemistry 2007 new
Role of the catalytic metal during polymerization by DNA polymerase lambda. Miguel Garcia-Diaz, Katarzyna Bebenek, Joseph M Krahn, Lars C Pedersen, Thomas A Kunkel DNA repair 2007 topics set
Replication of 2-hydroxyadenine-containing DNA and recognition by human MutSalpha. Flavia Barone, Scott D McCulloch, Peter Macpherson, Giovanni Maga, Masami Yamada, Takehiko Nohmi, Anna Minoprio, Filomena Mazzei, Thomas A Kunkel, Peter Karran, Margherita Bignami DNA repair 2007 topics set
The X family portrait: structural insights into biological functions of X family polymerases. Andrea F Moon, Miguel Garcia-Diaz, Vinod K Batra, William A Beard, Katarzyna Bebenek, Thomas A Kunkel, Samuel H Wilson, Lars C Pedersen DNA repair 2007 topics set
p53 suppression overwhelms DNA polymerase eta deficiency in determining the cellular UV DNA damage response. Rebecca R Laposa, Luzviminda Feeney, Eileen Crowley, Sebastien de Feraudy, James E Cleaver DNA repair 2007 new
Comparative evaluation of the activity of antivirals towards feline immunodeficiency virus in different cell culture systems. F J U M van der Meer, N M P Schuurman, Jan Balzarini, H F Egberink Antiviral research 2007 new
Antiviral activity of 3-(3,5-dimethylbenzyl)uracil derivatives against HIV-1 and HCMV. Tokumi Maruyama, Yosuke Demizu, Shigetada Kozai, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoecks, Graciella Andrei, Erik De Clercq Nucleosides, nucleotides & nucleic acids 2007 pols set
Crosslinking of the NER damage recognition proteins XPC-HR23B, XPA and RPA to photoreactive probes that mimic DNA damages. Ekaterina A Maltseva, Nadejda I Rechkunova, Ludovic C Gillet, Irina O Petruseva, Orlando D Schärer, Olga I Lavrik Biochimica et biophysica acta 2007 new
Synthesis and anti-HIV activity evaluation of 1-[(alkenyl or alkynyl or alkyloxy)methyl]-5-alkyl-6-(1-naphthoyl)-2,4-pyrimidinediones as novel non-nucleoside HIV-1 reverse transcriptase inhibitors. Lei Ji, Fen-Er Chen, Bin Xie, Erik De Clercq, Jan Balzarini, Christophe Pannecouque European journal of medicinal chemistry 2007 pols set
Dynamic DNA helicase-DNA polymerase interactions assure processive replication fork movement. Samir M Hamdan, Donald E Johnson, Nathan A Tanner, Jong-Bong Lee, Udi Qimron, Stanley Tabor, Antoine M van Oijen, Charles C Richardson Molecular cell 2007 pols set
Synthesis of novel derivatives of 4-amino-3-(2-furyl)-5-mercapto-1,2,4-triazole as potential HIV-1 NNRTIs. Jingde Wu, Xinyong Liu, Xianchao Cheng, Yuan Cao, Defeng Wang, Zhongjie Li, Wenfang Xu, Christophe Pannecouque, Myriam Witvrouw, Erik De Clercq Molecules (Basel, Switzerland) 2007 pols set
Synthesis and biological evaluation of 2,3-diaryl substituted-1,3-thiazolidin-4-ones as anti-HIV agents. Ravindra K Rawal, Raj Kamal Tripathi, S B Katti, Christophe Pannecouque, Erik De Clercq Medicinal chemistry (Shāriqah (United Arab Emirates)) 2007 pols set
Mechanisms of resistance associated with excision of incorporated nucleotide analogue inhibitors of HIV-1 reverse transcriptase. Matthias Götte Current opinion in HIV and AIDS 2007 pols set
Mitochondrial DNA depletion is a prevalent cause of multiple respiratory chain deficiency in childhood. Emmanuelle Sarzi, Alice Bourdon, Dominique Chrétien, Mohamed Zarhrate, Johanna Corcos, Abdelhamid Slama, Valérie Cormier-Daire, Pascale de Lonlay, Arnold Munnich, Agnès Rötig The Journal of pediatrics 2007 pols set
Site-directed mutagenesis in the fingers subdomain of HIV-1 reverse transcriptase reveals a specific role for the beta3-beta4 hairpin loop in dNTP selection. Scott J Garforth, Tae Woo Kim, Michael A. Parniak, Eric T Kool, Vinayaka R Prasad Journal of molecular biology 2007 pols set
Ribavirin and mycophenolic acid markedly potentiate the anti-hepatitis B virus activity of entecavir. Chunxiao Ying, Richard Colonno, Erik De Clercq, Johan Neyts Antiviral research 2007 new
DNA polymerase proofreading: active site switching catalyzed by the bacteriophage T4 DNA polymerase. Elizabeth Fidalgo da Silva, Linda J Reha-Krantz Nucleic acids research 2007 complete
Mutations at 65 and 70 within the context of a Q151M cluster in human immunodeficiency virus type 1 reverse transcriptase impact the susceptibility to the different nucleoside reverse transcriptase inhibitors in distinct ways. Kristel Van Laethem, Christophe Pannecouque, Anne-Mieke Vandamme Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2007 pols set
Synthesis and biological evaluation of alkenyldiarylmethane HIV-1 non-nucleoside reverse transcriptase inhibitors that possess increased hydrolytic stability. Matthew D Cullen, Bo-Liang Deng, Tracy L Hartman, Karen M Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman Journal of medicinal chemistry 2007 pols set
Mutations in the connection domain of HIV-1 reverse transcriptase increase 3'-azido-3'-deoxythymidine resistance. Galina N Nikolenko, Krista A Delviks-Frankenberry, Sarah Palmer, Frank Maldarelli, Matthew J Fivash, John M Coffin, Vinay K Pathak Proceedings of the National Academy of Sciences of the United States of America 2007 topics set
Effects of human leukocyte antigen class I genetic parameters on clinical outcomes and survival after initiation of highly active antiretroviral therapy. Zabrina L Brumme, Chanson J Brumme, Celia K S Chui, Theresa Mo, Brian Wynhoven, Conan K Woods, Bethany M Henrick, Robert S Hogg, Julio S G Montaner, P Richard Harrigan J Infect Dis 2007 new
A simple screening approach to reduce B*5701-associated abacavir hypersensitivity on the basis of sequence variation in HIV reverse transcriptase. Celia K S Chui, Zabrina L Brumme, Chanson J Brumme, Benita Yip, Elizabeth J Phillips, Julio S G Montaner, P Richard Harrigan Clin Infect Dis 2007 new
Distinct energetics and closing pathways for DNA polymerase beta with 8-oxoG template and different incoming nucleotides. Yazhen Wang, Tamar Schlick BMC Struct Biol 2007 new
Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates. Andrew J Low, Winnie W Y Dong, Dennison Chan, Tobias Sing, Ronald Swanstrom, Mark Jensen, Satish Pillai, Benjamin Good, P Richard Harrigan Aids 2007 new
Development and validation of a non-radioactive DNA polymerase assay for studying cytomegalovirus resistance to foscarnet. Alexandra Ducancelle, Sophie Alain, Françoise Petit, Marie-José Sanson Le Pors, Marie-Christine Mazeron J Virol Methods 2007 new
KDR expression is associated with the stage and cigarette smoking of the patients with lung cancer. She-Juan An, Qiang Nie, Zhi-Hong Chen, Qiu-Xiong Lin, Zhengqiang Wang, Zhongwen Xie, Shi-Liang Chen, Ying Huang, Ai-Ye Zhang, Jin-Feng Yan, Hong-Sui Wu, Jia-Ying Lin, Rong Li, Xu-Chao Zhang, Ai-Lin Guo, Tony S Mok, Yi-Long Wu Journal of cancer research and clinical oncology 2007 new
Partial purification and characterization of DNA polymerase beta-like enzyme from Plasmodium falciparum. Prapa Nunthawarasilp, Songsak Petmitr, Porntip Chavalitshewinkoon-Petmitr Mol Biochem Parasitol 2007 new
HIV-1 reverse transcriptase inhibitors. Yazan El Safadi, Valérie Vivet-Boudou, Roland Marquet Appl Microbiol Biotechnol 2007 complete Roland Marquet*
HMGB1 is a cofactor in mammalian base excision repair. Rajendra Prasad, Yuan Liu, Leesa J Deterding, Vladimir P Poltoratsky, Padmini S Kedar, Julie K Horton, Shin-Ichiro Kanno, Kenjiro Asagoshi, Esther W Hou, Svetlana N Khodyreva, Olga I Lavrik, Kenneth B Tomer, Akira Yasui, Samuel H Wilson Molecular cell 2007 new
The unstructured C-terminus of the tau subunit of Escherichia coli DNA polymerase III holoenzyme is the site of interaction with the alpha subunit. Slobodan Jergic, Kiyoshi Ozawa, Neal K Williams, Xun-Cheng Su, Daniel D Scott, Samir M Hamdan, Jeffrey A Crowther, Gottfried Otting, Nicholas E Dixon Nucleic acids research 2007 pols set
Synthesis, biological activity, and crystal structure of potent nonnucleoside inhibitors of HIV-1 reverse transcriptase that retain activity against mutant forms of the enzyme. Marshall L Morningstar, Thomas Roth, David W Farnsworth, Marilyn B Kroeger Smith, Karen M Watson, Robert W Buckheit, Kalyan Das, Weiming Zhang, Edward Arnold, John G Julias, Stephen H Hughes, Christopher J Michejda Journal of medicinal chemistry 2007 pols set
Exchange of DNA polymerases at the replication fork of bacteriophage T7. Donald E Johnson, Masateru Takahashi, Samir M Hamdan, Seung-Joo Lee, Charles C Richardson Proceedings of the National Academy of Sciences of the United States of America 2007 topics set
Characterization of promoter regulatory elements involved in downexpression of the DNA polymerase kappa in colorectal cancer. Fanny Lemée, Clarisse Bavoux, Marie-Jeanne Pillaire, Anne Bieth, Carlos Renato Machado, Sérgio Danilo Junho Pena, R Guimbaud, Janick Selves, Jean-Sébastien Hoffmann, Christophe Cazaux Oncogene 2007 new
Expanding the repertoire of DNA polymerase substrates: template-instructed incorporation of non-nucleoside triphosphate analogues by DNA polymerases beta and lambda. Emmanuele Crespan, Ludmila Alexandrova, Anastasiya Khandazhinskaya, Maxim Jasko, Marina Kukhanova, Giuseppe Villani, Ulrich Hübscher, Silvio Spadari, Giovanni Maga Nucleic acids research 2007 new
Evidence that in xeroderma pigmentosum variant cells, which lack DNA polymerase eta, DNA polymerase iota causes the very high frequency and unique spectrum of UV-induced mutations. Yun Wang, Roger Woodgate, Terrence P McManus, Samantha Mead, J Justin McCormick, Veronica M Maher Cancer research 2007 new
Replisome fate upon encountering a leading strand block and clearance from DNA by recombination proteins. Peter McInerney, Mike E O'Donnell The Journal of biological chemistry 2007 topics set
Overexpression of DNA polymerase beta results in an increased rate of frameshift mutations during base excision repair. Katie Chan, Sue Houlbrook, Qiu-Mei Zhang, Mark Harrison, Ian D Hickson, Grigory L Dianov Mutagenesis 2007 new
DNA polymerase eta is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse. Frédéric Delbos, Said Aoufouchi, Ahmad Faili, Jean-Claude Weill, Claude-Agnès Reynaud J Exp Med 2007 new
Multiple molecular markers as predictors of colorectal cancer in patients with normal perioperative serum carcinoembryonic antigen levels. Jaw-Yuan Wang, Shiu-Ru Lin, Deng-Chyang Wu, Chien-Yu Lu, Fang-Jung Yu, Jan-Sing Hsieh, Tian-Lu Cheng, Lok-Beng Koay, Yih-Huei Uen Clinical cancer research : an official journal of the American Association for Cancer Research 2007 new
Correlation of mitochondrial superoxide dismutase and DNA polymerase beta in mammalian dermal fibroblasts with species maximal lifespan. Melanie F Brown, Jeffrey A Stuart Mech Ageing Dev 2007 topics set
DNA damage reduces Taq DNA polymerase fidelity and PCR amplification efficiency. Jan A Sikorsky, Donald A Primerano, Terry W Fenger, James Denvir Biochem Biophys Res Commun 2007 topics set
Diminished efficiency of HIV-1 reverse transcriptase containing the K65R and M184V drug resistance mutations. Fernando A Frankel, Cédric F Invernizzi, Maureen Oliveira, Mark A. Wainberg AIDS (London, England) 2007 pols set
Hydrophobic amino acid and single-atom substitutions increase DNA polymerase selectivity. Nicolas Z Rudinger, Ramon Kranaster, Andreas Marx Chemistry & biology 2007 complete Andreas Marx*
Conformational dynamics of DNA polymerase probed with a novel fluorescent DNA base analogue. Gudrun Stengel, JP Gill, Peter Sandin, L Marcus Wilhelmsson, Bo Albinsson, Bengt Nordén, David P Millar Biochemistry 2007 topics set
HIV-1 drug resistance surveillance using dried whole blood spots. Silvia Bertagnolio, Luis Soto-Ramirez, Richard Pilon, Roberto Rodriguez, Monica Viveros, Luis Fuentes, P Richard Harrigan, Theresa Mo, Don Sutherland, Paul Sandstrom Antivir Ther 2007 new
Duplex strand joining reactions catalyzed by vaccinia virus DNA polymerase. Michael D Hamilton, Anthony A Nuara, Don B Gammon, R Mark Buller, David H Evans Nucleic acids research 2007 complete David H Evans*
What a difference a decade makes: insights into translesion DNA synthesis. Wei Wen Yang, Roger Woodgate Proceedings of the National Academy of Sciences of the United States of America 2007 topics set
Structure of the ubiquitin-binding zinc finger domain of human DNA Y-polymerase eta. Martha G Bomar, Ming-Tao Pai, Shiou-Ru Tzeng, Shawn Shun-Cheng Li, Pei Zhou EMBO Rep 2007 complete Pei Zhou*
Structure of the RNA-binding domain of telomerase: implications for RNA recognition and binding. Susan Rouda, Emmanuel Skordalakes Structure (London, England : 1993) 2007 complete Emmanuel Skordalakes*
DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination. Xiaoming Wu, Janet Stavnezer J Exp Med 2007 new
Elongation of palindromic repetitive DNA by DNA polymerase from hyperthermophilic archaea: a mechanism of DNA elongation and diversification. Norio Ogata Biochimie 2007 complete Norio Ogata*
N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance. Soo-Huey Yap, Chih-Wei Sheen, Jonathan Fahey, Mark Zanin, David Tyssen, Viviane Dias Lima, Brian Wynhoven, Michael Kuiper, Nicolas Sluis-Cremer, P Richard Harrigan, Gilda Tachedjian PLoS Med 2007 partial results
A novel mechanism of selectivity against AZT by the human mitochondrial DNA polymerase. Jeremiah W Hanes, Kenneth A Johnson Nucleic acids research 2007 new
Fidelity and processivity of reverse transcription by the human mitochondrial DNA polymerase. Harold R Lee, Kenneth A Johnson The Journal of biological chemistry 2007 pols set
Mechanism of abasic lesion bypass catalyzed by a Y-family DNA polymerase. Kevin A Fiala, Cameron D Hypes, Zucai Suo The Journal of biological chemistry 2007 topics set
Complex formation of yeast Rev1 with DNA polymerase eta. Narottam Acharya, Lajos Haracska, Satya Prakash, Louise Prakash Molecular and cellular biology 2007 new
Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases. Andrea J Berman, Satwik Kamtekar, Jessica L Goodman, José María Lázaro, Miguel de Vega, Luis Blanco, Margarita Salas, Thomas A Steitz The EMBO journal 2007 topics set
Enzymatic therapeutic index of acyclovir. Viral versus human polymerase gamma specificity. Jeremiah W Hanes, Yali Zhu, Deborah S Parris, Kenneth A Johnson The Journal of biological chemistry 2007 new
The EM structure of human DNA polymerase gamma reveals a localized contact between the catalytic and accessory subunits. Elena Yakubovskaya, Mark Lukin, Zhixin Chen, John Berriman, Joseph S Wall, Ryuji Kobayashi, Caroline Kisker, Daniel F Bogenhagen The EMBO journal 2007 pols set
The active site residue Valine 867 in human telomerase reverse transcriptase influences nucleotide incorporation and fidelity. William C Drosopoulos, Vinayaka R Prasad Nucleic acids research 2007 partial results
Modifying the beta,gamma leaving-group bridging oxygen alters nucleotide incorporation efficiency, fidelity, and the catalytic mechanism of DNA polymerase beta. Christopher A Sucato, Thomas G Upton, Boris A Kashemirov, Vinod K Batra, Václav Martínek, Yun Xiang, William A Beard, Lars C Pedersen, Samuel H Wilson, Charles E McKenna, Jan Florián, Arieh Warshel, Myron F Goodman Biochemistry 2007 topics set
[Complex of repair DNA polymerase beta with autonomous 3'-->5'-exonuclease shows increased accuracy of DNA synthesis]. N V Beliakova, T P Kravetskaia, O K Legina, N L Ronzhina, Igor V Shevelev, V M Krutiakov Izv Akad Nauk Ser Biol 2007 new
Molecular breeding of polymerases for amplification of ancient DNA. Marc d'Abbadie, Michael Hofreiter, Alexandra Vaisman, David Loakes, Didier Gasparutto, Jean Cadet, Roger Woodgate, Svante Pääbo, Philipp Holliger Nature biotechnology 2007 pols set
Interaction of the family-B DNA polymerase from the archaeon Pyrococcus furiosus with deaminated bases. Sukhvinder Gill, Rory O'Neill, Richard J Lewis, Bernard A Connolly Journal of molecular biology 2007 partial results
Yeast DNA polymerase epsilon participates in leading-strand DNA replication. Zachary F Pursell, Isabelle Isoz, Else-Britt Lundström, Erik Johansson, Thomas A Kunkel Science 2007 pols set
The noncatalytic C-terminus of AtPOLK Y-family DNA polymerase affects synthesis fidelity, mismatch extension and translesion replication. María Victoria García-Ortiz, Teresa Roldán-Arjona, Rafael R Ariza FEBS J 2007 complete Rafael R Ariza*
Human DNA polymerase kappa encircles DNA: implications for mismatch extension and lesion bypass. Samer Lone, Sharon A Townson, Sacha N Uljon, Robert E Johnson, Amrita Brahma, Deepak T Nair, Satya Prakash, Louise Prakash, Aneel K Aggarwal Molecular cell 2007 pols set
Specific terminal labeling of DNA molecules. Yasushi Shigemori, Michio Oishi BioTechniques 2007 topics set
Cloning, expression and characterization of human tissue-specific DNA polymerase lambda2. Fu Gu, Chun You, JianPing Liu, Ao Chen, Yao Yu, Xiang Wang, DaFang Wan, JianRen Gu, HanYing Yuan, Yingqian Li, Hong Lü Sci China C Life Sci 2007 pols set
Analysis of amino acids in the beta7-beta8 loop of human immunodeficiency virus type 1 reverse transcriptase for their role in virus replication. Alok Mulky, B Christie Vu, Joan A Conway, Stephen H Hughes, John C Kappes Journal of molecular biology 2007 pols set
Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerases. Christian Castro, Eric D Smidansky, Kenneth R Maksimchuk, Jamie J Arnold, Victoria S Korneeva, Matthias Götte, William H Konigsberg, Craig E Cameron Proceedings of the National Academy of Sciences of the United States of America 2007 complete
Targeting to the endoplasmic reticulum improves the folding of recombinant human telomerase reverse transcriptase. Chia-Kuei Wu, Karine Gousset, Stephen H Hughes Protein expression and purification 2007 new
Structural descriptors of gp120 V3 loop for the prediction of HIV-1 coreceptor usage. Oliver Sander, Tobias Sing, Ingolf Sommer, Andrew J Low, Peter K Cheung, P Richard Harrigan, Thomas Lengauer, Francisco S Domingues PLoS Comput Biol 2007 new
Lesion bypass activity of DNA polymerase A from the extremely radioresistant organism Deinococcus radiodurans. Kathrin Heinz, Andreas Marx The Journal of biological chemistry 2007 new
DNA polymerase beta catalytic efficiency mirrors the Asn279-dCTP H-bonding strength. Václav Martínek, Urban Bren, Myron F Goodman, Arieh Warshel, Jan Florián FEBS letters 2007 pols set
Anti-tumor effects of the glycolipids fraction from spinach which inhibited DNA polymerase activity. Naoki Maeda, Yasuo Kokai, Seiji Ohtani, Hiroeki Sahara, Takahiko Hada, Chisato Ishimaru, Isoko Kuriyama, Yuko Yonezawa, Hiroshi Iijima, Hiromi Yoshida, Noriyuki Sato, Yoshiyuki Mizushina Nutr Cancer 2007 new
Reassessment of the in vivo functions of DNA polymerase I and RNase H in bacterial cell growth. Sanae Fukushima, Mitsuhiro Itaya, Hiroaki Kato, Naotake Ogasawara, Hirofumi Yoshikawa J Bacteriol 2007 new
Structure/function analysis of the interaction of adenomatous polyposis coli with DNA polymerase beta and its implications for base excision repair. Ramesh Balusu, Aruna S Jaiswal, Melissa L Armas, Chanakya N Kundu, Linda B Bloom, Satya Narayan Biochemistry 2007 new
Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family. Matthew Hogg, Pierre Aller, William H Konigsberg, Susan S Wallace, Sylvie Doublié The Journal of biological chemistry 2007 complete
A quantum mechanical investigation of possible mechanisms for the nucleotidyl transfer reaction catalyzed by DNA polymerase beta. Mihaela D Bojin, Tamar Schlick J Phys Chem B 2007 new
Escherichia coli DNA polymerase IV contributes to spontaneous mutagenesis at coding sequences but not microsatellite alleles. Kimberly D Jacob, Kristin A Eckert Mutation research 2007 pols set
Anti-tumor effects of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha. Naoki Maeda, Yasuo Kokai, Seiji Ohtani, Hiroeki Sahara, Isoko Kuriyama, Shinji Kamisuki, Shunya Takahashi, Kengo Sakaguchi, Fumio Sugawara, Hiromi Yoshida, Noriyuki Sato, Yoshiyuki Mizushina Biochem Biophys Res Commun 2007 pols set
Differing conformational pathways before and after chemistry for insertion of dATP versus dCTP opposite 8-oxoG in DNA polymerase beta. Yazhen Wang, Sujatha Reddy, William A Beard, Samuel H Wilson, Tamar Schlick Biophys J 2007 pols set
The role of specific amino acid residues in the active site of Escherichia coli DNA polymerase I on translesion DNA synthesis across from and past an N-2-aminofluorene adduct. Samer Lone, Louis J Romano Biochemistry 2007 pols set
DNA polymerase delta-dependent repair of DNA single strand breaks containing 3'-end proximal lesions. Jason L Parsons, Bradley D Preston, Timothy R O'Connor, Grigory L Dianov Nucleic acids research 2007 new
Elevated expression of DNA polymerase II increases spontaneous mutagenesis in Escherichia coli. Abu Amar M Al Mamun Mutation research 2007 pols set
Sequence-specific detection of individual DNA polymerase complexes in real time using a nanopore. Seico Benner, Roger J A Chen, Noah A Wilson, Robin Abu-Shumays, Nicholas Hurt, Kate R Lieberman, David W Deamer, William B Dunbar, Mark Akeson Nat Nanotechnol 2007 complete Kate R Lieberman*
DNA polymerase beta catalysis: are different mechanisms possible? Ian L Alberts, Yazhen Wang, Tamar Schlick Journal of the American Chemical Society 2007 new
DNA polymerase mutations in drug-resistant herpes simplex virus mutants determine in vivo neurovirulence and drug-enzyme interactions. Gracíela Andrei, Pierre Fiten, Matheus Froeyen, Erik De Clercq, Ghislain Opdenakker, Robert Snoeck Antivir Ther 2007 new
Mcm10 and And-1/CTF4 recruit DNA polymerase alpha to chromatin for initiation of DNA replication. Wenge Zhu, Chinweike Ukomadu, Sudhakar Jha, Takeshi Senga, Suman K Dhar, James A Wohlschlegel, Leta K Nutt, Sally Kornbluth, Anindya Dutta Genes Dev 2007 new
Cloning, purification, and characterization of a new DNA polymerase from a hyperthermophilic archaeon, Thermococcus sp. NA1. Yun Jae Kim, Hyun Sook Lee, Seung Seob Bae, Jeong Ho Jeon, Jae Kyu Lim, Yona Cho, Ki Hoon Nam, Sung Gyun Kang, Soon-Jong Kim, Suk-Tae Kwon, Jung-Hyun Lee J Microbiol Biotechnol 2007 new
Single-step purification of recombinant Thermus aquaticus DNA polymerase using DNA-aptamer immobilized novel affinity magnetic beads. Huseyin Avni Oktem, Gulay Bayramoglu, V Cengiz Ozalp, M Yakup Arica Biotechnol Prog 2007 pols set
A novel interaction between DNA ligase III and DNA polymerase gamma plays an essential role in mitochondrial DNA stability. Ananya De, Colin Campbell Biochem J 2007 new
The dnaE173 mutator mutation confers on the alpha subunit of Escherichia coli DNA polymerase III a capacity for highly processive DNA synthesis and stable binding to primer/template DNA. Fusamitsu Yanagihara, Shonen Yoshida, Yutaka Sugaya, Hisaji Maki Genes Genet Syst 2007 pols set
Interactions of the DNA polymerase X from African swine fever virus with gapped DNA substrates. Quantitative analysis of functional structures of the formed complexes. Maria J Jezewska, Paul J Bujalowski, Wlodzimierz Bujalowski Biochemistry 2007 new
The human GINS complex binds to and specifically stimulates human DNA polymerase alpha-primase. Mariarosaria De Falco, Elena Ferrari, Mariarita De Felice, Mosè Rossi, Ulrich Hübscher, Francesca M Pisani EMBO Rep 2007 pols set
Tobacco proliferating cell nuclear antigen binds directly and stimulates both activity and processivity of ddNTP-sensitive mungbean DNA polymerase. Sujit Roy, Swarup Roy Choudhury, Sunil K Mukherjee, Dibyendu Narayan SenGupta Arch Biochem Biophys 2007 new
Structure and function of a mycobacterial NHEJ DNA repair polymerase. Robert S Pitcher, Nigel C Brissett, Angel J Picher, Paula Andrade, Raquel Juarez, Darren Thompson, Gavin C Fox, Luis Blanco, Aidan J Doherty Journal of molecular biology 2007 partial results
Analysis of DNA polymerase activity in vitro using non-radioactive primer extension assay in an automated DNA sequencer. D O Lopes, Carlos Gustavo Regis-da-Silva, Alice Machado-Silva, Andréa Mara Macedo, Glória Regina Franco, Jean-Sébastien Hoffmann, Christophe Cazaux, Sérgio Danilo Junho Pena, Santuza Maria Ribeiro Teixeira, Carlos Renato Machado Genet Mol Res 2007 new
Determining human immunodeficiency virus coreceptor use in a clinical setting: degree of correlation between two phenotypic assays and a bioinformatic model. Katharina Skrabal, Andrew J Low, Winnie W Y Dong, Tobias Sing, Peter K Cheung, Fabrizio Mammano, P Richard Harrigan J Clin Microbiol 2007 new
Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1. Zabrina L Brumme, Chanson J Brumme, David Heckerman, Bette T Korber, Marcus Daniels, Jonathan Carlson, Carl Kadie, Tanmoy Bhattacharya, Celia K S Chui, James Szinger, Theresa Mo, Robert S Hogg, Julio S G Montaner, Nicole Frahm, Christian Brander, Bruce D Walker, P Richard Harrigan PLoS Pathog 2007 new
INCURVATA2 encodes the catalytic subunit of DNA Polymerase alpha and interacts with genes involved in chromatin-mediated cellular memory in Arabidopsis thaliana. José María Barrero, Rebeca González-Bayón, Juan Carlos del Pozo, María Rosa Ponce, José Luis Micol Plant Cell 2007 new
Evolving a thermostable DNA polymerase that amplifies from highly damaged templates. Christian Gloeckner, Katharina B M Sauter, Andreas Marx Angew Chem Int Ed Engl 2007 new
DNA polymerase recognition of 2'-deoxy-2'-fluoroarabinonucleoside 5'-triphosphates (2'F-araNTPs). Chang G Peng, Masad J Damha Nucleosides, nucleotides & nucleic acids 2007 new
Highly efficient isothermal DNA amplification system using three elements of 5'-DNA-RNA-3' chimeric primers, RNaseH and strand-displacing DNA polymerase. Hiroyuki Mukai, Takashi Uemori, Osamu Takeda, Eiji Kobayashi, Junko Yamamoto, Kazue Nishiwaki, Tatsuji Enoki, Hiroaki Sagawa, Kiyozo Asada, Ikunoshin Kato J Biochem 2007 new
Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. Bruno Marchand, Kirsten L White, John K Ly, Nicolas A Margot, Ruth Wang, Martin J McDermott, Michael D Miller, Matthias Götte Antimicrob Agents Chemother 2007 topics set
Nitroimidazoles Part 6. Synthesis, structure and in vitro anti-HIV activity of new 5-substituted piperazinyl-4-nitroimidazole derivatives. Najim A Al-Masoudi, Yaseen A Al-Soud, Erik De Clercq, Christophe Pannecouque Antiviral chemistry & chemotherapy 2007 new
Involvement of phage phi29 DNA polymerase and terminal protein subdomains in conferring specificity during initiation of protein-primed DNA replication. Patricia Pérez-Arnaiz, Elisa Longás, Laurentino Villar, José María Lázaro, Margarita Salas, Miguel de Vega Nucleic acids research 2007 pols set
A unique error signature for human DNA polymerase nu. Mercedes E Arana, Kei-ichi Takata, Miguel Garcia-Diaz, Richard D Wood, Thomas A Kunkel DNA repair 2007 partial results
Increased catalytic activity and altered fidelity of human DNA polymerase iota in the presence of manganese. Ekaterina G Frank, Roger Woodgate The Journal of biological chemistry 2007 pols set
Relationship of potency and resilience to drug resistant mutations for GW420867X revealed by crystal structures of inhibitor complexes for wild-type, Leu100Ile, Lys101Glu, and Tyr188Cys mutant HIV-1 reverse transcriptases. Jingshan Ren, Charles E Nichols, Phillip P Chamberlain, Kurt L Weaver, Steven A Short, Joseph H Chan, Jörg-Peter Kleim, David K Stammers J Med Chem 2007 partial results
Accessory proteins assist exonuclease-deficient bacteriophage T4 DNA polymerase in replicating past an abasic site. Giuseppina Blanca, Emmanuelle Delagoutte, Nicolas Tanguy Le Gac, Neil P Johnson, Giuseppe Baldacci, Giuseppe Villani Biochem J 2007 pols set
Use of damaged DNA and dNTP substrates by the error-prone DNA polymerase X from African swine fever virus. Sandeep Kumar, Brandon J Lamarche, Ming-Daw Tsai Biochemistry 2007 new
Involvement of DNA polymerase beta in repair of ionizing radiation damage as measured by in vitro plasmid assays. Conchita Vens, Ingrid Hofland, Adrian C Begg Radiat Res 2007 new
Magnesium-cationic dummy atom molecules enhance representation of DNA polymerase beta in molecular dynamics simulations: improved accuracy in studies of structural features and mutational effects. Peter Oelschlaeger, Marco Klahn, William A Beard, Samuel H Wilson, Arieh Warshel Journal of molecular biology 2007 pols set
(R)-beta,gamma-fluoromethylene-dGTP-DNA ternary complex with DNA polymerase beta. Charles E McKenna, Boris A Kashemirov, Thomas G Upton, Vinod K Batra, Myron F Goodman, Lars C Pedersen, William A Beard, Samuel H Wilson Journal of the American Chemical Society 2007 topics set
A second proliferating cell nuclear antigen loader complex, Ctf18-replication factor C, stimulates DNA polymerase eta activity. Yasushi Shiomi, Chikahide Masutani, Fumio Hanaoka, Hiroshi Kimura, Toshiki Tsurimoto The Journal of biological chemistry 2007 new
Insertions in the beta3-beta4 loop of reverse transcriptase of human immunodeficiency virus type 1 and their mechanism of action, influence on drug susceptibility and viral replication capacity. Dirk Eggink, Marleen C D G Huigen, Charles A B Boucher, Matthias Götte, Monique Nijhuis Antiviral Res 2007 topics set
Performance of a World Health Organization first-line regimen (stavudine/lamivudine/nevirapine) in antiretroviral-naive individuals in a Western setting. L W Y Tam, Robert S Hogg, Benita Yip, J S G Montaner, P Richard Harrigan, Chanson J Brumme HIV Med 2007 new
Assay of HIV gp41 amino acid sequence to identify baseline variation and mutation development in patients with virologic failure on enfuvirtide. M R Loutfy, J M Raboud, J S G Montaner, T Antoniou, Brian Wynhoven, F Smaill, D Rouleau, J Gill, W Schlech, Zabrina L Brumme, Theresa Mo, K Gough, A Rachlis, P Richard Harrigan, S L Walmsley Antiviral Res 2007 new
Bayesian network analysis of resistance pathways against HIV-1 protease inhibitors. K Deforche, R Camacho, Z Grossman, T Silander, M A Soares, Y Moreau, R W Shafer, Kristel Van Laethem, A P Carvalho, Brian Wynhoven, P Cane, Joke Snoeck, J Clarke, S Sirivichayakul, Koyo Ariyoshi, A Holguin, H Rudich, R Rodrigues, M B Bouzas, P Cahn, L F Brigido, V Soriano, Wataru Sugiura, P Phanuphak, L Morris, J Weber, D Pillay, A Tanuri, P Richard Harrigan, J M Shapiro, D A Katzenstein, R Kantor, A-M Vandamme Infect Genet Evol 2007 new
A dideoxynucleotide-sensitive DNA polymerase activity characterized from endoreduplicating cells of mungbean (Vigna radiata L.) during ontogeny of cotyledons. Sujit Roy, Sailendra Nath Sarkar, Sanjay Kumar Singh, Dibyendu Narayan SenGupta FEBS J 2007 new
Characterization of a triple DNA polymerase replisome. Peter McInerney, Aaron Johnson, Francine Katz, Mike E O'Donnell Molecular cell 2007 new
The accessory subunit B of DNA polymerase gamma is required for mitochondrial replisome function. Géraldine Farge, Xuan Hoi Pham, Teresa Holmlund, Ivan Khorostov, Maria Falkenberg Nucleic acids research 2007 new
Participation of the fingers subdomain of Escherichia coli DNA polymerase I in the strand displacement synthesis of DNA. Kamalendra Singh, Aashish Srivastava, Smita S Patel, Mukund J Modak The Journal of biological chemistry 2007 pols set
Epicatechin conjugated with fatty acid is a potent inhibitor of DNA polymerase and angiogenesis. Kiminori Matsubara, Akiko Saito, Akira Tanaka, Noriyuki Nakajima, Reiko Akagi, Masaharu Mori, Yoshiyuki Mizushina Life Sci 2007 new
Architecture of the bacteriophage T4 replication complex revealed with nanoscale biopointers. Nancy G Nossal, Alexander M Makhov, Paul D Chastain, Charles E Jones, Jack D Griffith The Journal of biological chemistry 2007 complete
3'-Azido-3'-deoxythymidine-(5')-tetraphospho-(5')-adenosine, the product of ATP-mediated excision of chain-terminating AZTMP, is a potent chain-terminating substrate for HIV-1 reverse transcriptase. Sanjeewa Dharmasena, Zita Pongracz, Edward Arnold, Stefan G Sarafianos, Michael A. Parniak Biochemistry 2007 partial results
Mitochondrial DNA defects in Saccharomyces cerevisiae caused by functional interactions between DNA polymerase gamma mutations associated with disease in human. Enrico Baruffini, Iliana Ferrero, Françoise Foury Biochimica et biophysica acta 2007 complete Enrico Baruffini*
Multiple primer extension by DNA polymerase on a novel plastic DNA array coated with a biocompatible polymer. Kenji Kinoshita, Kentaro Fujimoto, Toru Yakabe, Shin Saito, Yuzo Hamaguchi, Takayuki Kikuchi, Ken Nonaka, Shigenori Murata, Daisuke Masuda, Wataru Takada, Sohei Funaoka, Susumu Arai, Hisao Nakanishi, Kanehisa Yokoyama, Kazuhiko Fujiwara, Kiminori Matsubara Nucleic acids research 2007 new
DNA polymerase V allows bypass of toxic guanine oxidation products in vivo. William L Neeley, Sarah Delaney, Yuriy O Alekseyev, Daniel F Jarosz, James C Delaney, Graham C Walker, John M Essigmann The Journal of biological chemistry 2007 new
A 21-base pair insertion/duplication at codon 69 of the HIV type 1 reverse transcriptase in a patient undergoing multiple nucleoside therapy. P Richard Harrigan, Theresa Mo, Jennifer Hirsch, Zabrina L Brumme, Paula McKenna, Lee Bacheler AIDS Res Hum Retroviruses 2007 topics set
"False" thymine-1H-Enol guanine base pair. low misinsertion rate by DNA polymerase explained by computational chemistry consideration. E Seclaman, L Kurunczi, Z Simon Biochemistry (Mosc) 2007 new
Human DNA polymerase alpha uses a combination of positive and negative selectivity to polymerize purine dNTPs with high fidelity. Jeff W Beckman, Kristi Kincaid, Michal Hocek, Thomas E Spratt, Joachim W Engels, Richard Cosstick, Robert D Kuchta Biochemistry 2007 pols set
Molecular analysis of DNA polymerase eta gene in Japanese patients diagnosed as xeroderma pigmentosum variant type. Miki Tanioka, Taro Masaki, Ryusuke Ono, Tohru Nagano, Eriko Otoshi-Honda, Yasuhiro Matsumura, Masahiro Takigawa, Hiroki Inui, Yoshiki Miyachi, Shinichi Moriwaki, Chikako Nishigori J Invest Dermatol 2007 new
The pyrophosphate analogue foscarnet traps the pre-translocational state of HIV-1 reverse transcriptase in a Brownian ratchet model of polymerase translocation. Bruno Marchand, Egor P Tchesnokov, Matthias Götte The Journal of biological chemistry 2007 partial results
Ability of polymerase eta and T7 DNA polymerase to bypass bulge structures. Vincent J Cannistraro, John-Stephen Taylor The Journal of biological chemistry 2007 pols set
Model for forward polymerization and switching transition between polymerase and exonuclease sites by DNA polymerase molecular motors. Ping Xie Arch Biochem Biophys 2007 new
Replisome mechanics: insights into a twin DNA polymerase machine. Richard T Pomerantz, Mike E O'Donnell Trends Microbiol 2007 new
Caught bending the A-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide. Karl E Zahn, Hassan Belrhali, Susan S Wallace, Sylvie Doublié Biochemistry 2007 topics set
N.BspD6I DNA nickase strongly stimulates template-independent synthesis of non-palindromic repetitive DNA by Bst DNA polymerase. Nadezhda V Zyrina, Lyudmila A Zheleznaya, Eugene V Dvoretsky, Victor D Vasiliev, Andrei Chernov, Nicholas I Matvienko Biol Chem 2007 pols set
Ionizing radiation sensitivity of DNA polymerase lambda-deficient cells. Christie Vermeulen, Barbara Bertocci, Adrian C Begg, Conchita Vens Radiat Res 2007 new
Highly selective action of triphosphate metabolite of 4'-ethynyl D4T: a novel anti-HIV compound against HIV-1 RT. Guangwei Yang, Ginger E Dutschman, Chuan-Jen Wang, Hiromichi Tanaka, Masanori Baba, Karen S Anderson, Yung-Chi Cheng Antiviral Res 2007 new
Hydrogen bonding of 7,8-dihydro-8-oxodeoxyguanosine with a charged residue in the little finger domain determines miscoding events in Sulfolobus solfataricus DNA polymerase Dpo4. Robert Lawton Eoff, Adriana Irimia, Karen C Angel, Martin Egli, F Peter Guengerich The Journal of biological chemistry 2007 topics set
Reevaluating the capability of Taq DNA polymerase: long PCR amplification. Hayan Lee, Kyung-Nam Kim, Young Kee Chae Protein Pept Lett 2007 pols set
Possible role of DNA polymerase beta in protecting human bronchial epithelial cells against cytotoxicity of hydroquinone. Da-Lin Hu, Huan-Wen Tang, Hai-Rong Liang, Dong-Sheng Tang, Yi-Ming Liu, Wei-Dong Ji, Jian-Hui Yuan, Yun He, Zheng-Yu Zhu, Jian-Ping Yang, Dao-Kui Fang, Yan Sha, Xiao-Zhi Tu, Zhi-Xiong Zhuang Biomed Environ Sci 2007 new
Characterization of the DNA- and dNTP-binding activities of the human cytomegalovirus DNA polymerase catalytic subunit UL54. Frédéric Picard-Jean, Isabelle Bougie, Martin Bisaillon Biochem J 2007 pols set
Nodulisporol and Nodulisporone, novel specific inhibitors of human DNA polymerase lambda from a fungus, Nodulisporium sp. Shinji Kamisuki, Chisato Ishimaru, Kadohiro Onoda, Isoko Kuriyama, Noriko Ida, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina Bioorg Med Chem 2007 pols set
Sulfolobus solfataricus DNA polymerase Dpo4 is partially inhibited by "wobble" pairing between O6-methylguanine and cytosine, but accurate bypass is preferred. Robert Lawton Eoff, Adriana Irimia, Martin Egli, F Peter Guengerich The Journal of biological chemistry 2007 topics set
Upregulation of error-prone DNA polymerases beta and kappa slows down fork progression without activating the replication checkpoint. Marie-Jeanne Pillaire, Rémy Betous, Chiara Conti, Jerzy Czaplicki, Philippe Pasero, Aaron Bensimon, Christophe Cazaux, Jean-Sébastien Hoffmann Cell Cycle 2007 new
A function for the psi subunit in loading the Escherichia coli DNA polymerase sliding clamp. Stephen G Anderson, Christopher R Williams, Mike E O'Donnell, Linda B Bloom The Journal of biological chemistry 2007 pols set
The T4 phage UvsW protein contains both DNA unwinding and strand annealing activities. Scott W Nelson, Stephen J Benkovic The Journal of biological chemistry 2007 topics set
A ubiquitin-binding motif in the translesion DNA polymerase Rev1 mediates its essential functional interaction with ubiquitinated proliferating cell nuclear antigen in response to DNA damage. Adam Wood, Parie Garg, Peter M J Burgers The Journal of biological chemistry 2007 new
Enzymatic incorporation of LNA nucleotides into DNA strands. Rakesh N Veedu, Birte Vester, Jesper Wengel Chembiochem : a European journal of chemical biology 2007 topics set
Single-molecule and ensemble fluorescence assays for a functionally important conformational change in T7 DNA polymerase. Guobin Luo, Michael Wang, William H Konigsberg, X Sunney Xie Proceedings of the National Academy of Sciences of the United States of America 2007 pols set
Different mutations in the HHV-6 DNA polymerase gene accounting for resistance to foscarnet. Pascale Bonnafous, Lieve Naesens, Stéphanie Petrella, Agnès Gautheret-Dejean, David Boutolleau, Wladimir Sougakoff, Henri Agut Antivir Ther 2007 new
Bypass of DNA lesions generated during anticancer treatment with cisplatin by DNA polymerase eta. Aaron Alt, Katja Lammens, Claudia Chiocchini, Alfred Lammens, J Carsten Pieck, David Kuch, Karl-Peter Hopfner, Thomas Carell Science 2007 topics set
Highly tolerated amino acid substitutions increase the fidelity of Escherichia coli DNA polymerase I. Ern Loh, Juno Choe, Lawrence A Loeb The Journal of biological chemistry 2007 pols set
Unexpected efficient ab initio DNA synthesis at low temperature by using thermophilic DNA polymerase. Xingguo Liang, Tomohiro Kato, Hiroyuki Asanuma Nucleic Acids Symp Ser (Oxf) 2007 new
Conformational changes during normal and error-prone incorporation of nucleotides by a Y-family DNA polymerase detected by 2-aminopurine fluorescence. Angela M DeLucia, Nigel D F Grindley, Catherine M Joyce Biochemistry 2007 new
Biochemical properties of a plastidial DNA polymerase of rice. Ryo Takeuchi, Seisuke Kimura, Ai Saotome, Kengo Sakaguchi Plant Mol Biol 2007 new
Steric and electrostatic effects in DNA synthesis by the SOS-induced DNA polymerases II and IV of Escherichia coli. Adam P Silverman, Qingfei Jiang, Myron F Goodman, Eric T Kool Biochemistry 2007 topics set
The E295K DNA polymerase beta gastric cancer-associated variant interferes with base excision repair and induces cellular transformation. Tieming Lang, Shibani Dalal, Anna K Chikova, Daniel Dimaio, Joann B Sweasy Molecular and cellular biology 2007 topics set
Molecular basis of selectivity of nucleoside triphosphate incorporation opposite O6-benzylguanine by sulfolobus solfataricus DNA polymerase Dpo4: steady-state and pre-steady-state kinetics and x-ray crystallography of correct and incorrect pairing. Robert Lawton Eoff, Karen C Angel, Martin Egli, F Peter Guengerich The Journal of biological chemistry 2007 partial results
Structure and activity of Y-class DNA polymerase DPO4 from Sulfolobus solfataricus with templates containing the hydrophobic thymine analog 2,4-difluorotoluene. Adriana Irimia, Robert Lawton Eoff, Pradeep S Pallan, F Peter Guengerich, Martin Egli The Journal of biological chemistry 2007 topics set
Predicting HIV coreceptor usage on the basis of genetic and clinical covariates. Tobias Sing, Andrew J Low, Niko Beerenwinkel, Oliver Sander, Peter K Cheung, Francisco S Domingues, Joachim Büch, Martin Däumer, Rolf Kaiser, Thomas Lengauer, P Richard Harrigan Antivir Ther 2007 new
Crystallization and preliminary crystallographic study of DNA polymerase from Pyrococcus furiosus. Hirokazu Nishida, Maiko Tanabe, Yoshizumi Ishino, Takuji Oyama, Kosuke Morikawa Protein Pept Lett 2007 pols set
The eukaryotic leading and lagging strand DNA polymerases are loaded onto primer-ends via separate mechanisms but have comparable processivity in the presence of PCNA. Olga Chilkova, Peter Stenlund, Isabelle Isoz, Carrie M W Stith, Pawel Grabowski, Else-Britt Lundström, Peter M J Burgers, Erik Johansson Nucleic acids research 2007 pols set
Interactions of the DNA polymerase X of African swine fever virus with double-stranded DNA. Functional structure of the complex. Maria J Jezewska, Paul J Bujalowski, Wlodzimierz Bujalowski Journal of molecular biology 2007 new
The checkpoint clamp, Rad9-Rad1-Hus1 complex, preferentially stimulates the activity of apurinic/apyrimidinic endonuclease 1 and DNA polymerase beta in long patch base excision repair. Agnieszka Gembka, Magali Toueille, Ekaterina Smirnova, Rainer Poltz, Elena Ferrari, Giuseppe Villani, Ulrich Hübscher Nucleic acids research 2007 new
Malignant transformation of the cultured human normal biliary tract epithelial cells induced by hepatitis C virus core protein. Ru-Fu Chen, Zhi-Hua Li, Ran-Yi Liu, Xian-He Kong, Qi-Bin Tang, Jie Wang Oncology reports 2007 new
Comparison of two gel filtration chromatographic methods for the purification of Lily symptomless virus. Ruoyu Wang, Jianhui Wang, Jinming Li, Yujue Wang, Zhongkui Xie, Lizhe An Journal of virological methods 2007 new
D- and L-2',3'-didehydro-2',3'-dideoxy-3'-fluoro-carbocyclic nucleosides: synthesis, anti-HIV activity and mechanism of resistance. Jianing Wang, Yunho Jin, Kimberly L Rapp, Raymond F Schinazi, Chung K Chu Journal of medicinal chemistry 2007 pols set
A peptide with HIV-1 reverse transcriptase inhibitory activity from the medicinal mushroom Russula paludosa. Jianbin Wang, H X Wang, T B Ng Peptides 2007 pols set
[DNA methylation of human telomerase reverse transcriptase promoter region in human ameloblastoma]. Ming Zhong, Ying Yan, Jie Wang, Jie Liu, Le Li, Yan-Bing Gong Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 2007 new
Rationally designed dual inhibitors of HIV reverse transcriptase and integrase. Zhengqiang Wang, Eric M Bennett, Daniel J Wilson, Christine E Salomon, Robert Vince Journal of medicinal chemistry 2007 pols set
Human Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA damage during replication. Sharbani Chattopadhyay, Anja-Katrin Bielinsky Mol Biol Cell 2007 new
DNA polymerase switching on homotrimeric PCNA at the replication fork of the euryarchaea Pyrococcus abyssi. Christophe Rouillon, Ghislaine Henneke, Didier Flament, Joël Querellou, Jean-Paul Raffin Journal of molecular biology 2007 new
Clonally amplified cardiac stem cells are regulated by Sca-1 signaling for efficient cardiovascular regeneration. Kento Tateishi, Eishi Ashihara, Naofumi Takehara, Tetsuya Nomura, Shoken Honsho, Takuo Nakagami, Shigehiro Morikawa, Tomosaburo Takahashi, Tomomi Ueyama, Hiroaki Matsubara, Hidemasa Oh Journal of cell science 2007 new
Characterization of a replication-competent, integrase-defective human immunodeficiency virus (HIV)/simian virus 40 chimera as a powerful tool for the discovery and validation of HIV integrase inhibitors. Dirk Daelemans, Richard Lu, Erik De Clercq, Alan Engelman Journal of virology 2007 pols set
The intricate structural chemistry of base excision repair machinery: implications for DNA damage recognition, removal, and repair. Kenichi Hitomi, Shigenori Iwai, John A Tainer DNA repair 2007 new
RNA-templated DNA repair. Francesca Storici, Katarzyna Bebenek, Thomas A Kunkel, Dmitry A Gordenin, Michael A Resnick Nature 2007 new
NNRTI-selected mutations at codon 190 of human immunodeficiency virus type 1 reverse transcriptase decrease susceptibility to stavudine and zidovudine. Stefania Paolucci, Fausto Baldanti, Giulia Campanini, Reynel Cancio, Amalia Belfiore, Giovanni Maga, Giuseppe Gerna Antiviral research 2007 pols set
Indolyl aryl sulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: role of two halogen atoms at the indole ring in developing new analogues with improved antiviral activity. Giuseppe La Regina, Antonio Coluccia, Francesco Piscitelli, Alberto Bergamini, Anna Sinistro, Antonella Cavazza, Giovanni Maga, Alberta Samuele, Samantha Zanoli, Ettore Novellino, Marino Artico, Romano Silvestri Journal of medicinal chemistry 2007 pols set
Investigation of novel lipid-functionalized PNA monomers as potential HIV-1 non-nucleoside reverse transcriptase and/or integrase inhibitors. Michael G Thomas, Giovanni Maga, Jean-François Mouscadet, Nicola M Howarth Nucleosides, nucleotides & nucleic acids 2007 pols set
Following an environmental carcinogen N2-dG adduct through replication: elucidating blockage and bypass in a high-fidelity DNA polymerase. Pingna Xu, Lida Oum, Lorena S Beese, Nicholas E Geacintov, Suse Broyde Nucleic acids research 2007 new
A highly conserved Tyrosine residue of family B DNA polymerases contributes to dictate translesion synthesis past 8-oxo-7,8-dihydro-2'-deoxyguanosine. Miguel de Vega, Margarita Salas Nucleic acids research 2007 topics set
Inhibition of telomerase activity and human telomerase reverse transcriptase gene expression by histone deacetylase inhibitor in human brain cancer cells. Aik Kia Khaw, Miranti Silasudjana, Birendranath Banerjee, Motoshi Suzuki, Rajamanickam Baskar, M Prakash Hande Mutation research 2007 new
The use of non-natural nucleotides to probe template-independent DNA synthesis. Anthony J Berdis, David McCutcheon Chembiochem 2007 topics set
Characterization of the uracil-DNA glycosylase activity of Epstein-Barr virus BKRF3 and its role in lytic viral DNA replication. Chih-Chung Lu, Ho-Ting Huang, Jiin-Tarng Wang, Geir Slupphaug, Tsai-Kun Li, Meng-Chuan Wu, Yi-Chun Chen, Chung-Pei Lee, Mei-Ru Chen Journal of virology 2007 complete Mei-Ru Chen*
Simian fetal brain progenitor cells for studying viral neuropathogenesis. Naoko Iwata, Hiroaki Yoshida, Minoru Tobiume, Fumiko Ono, Takuya Shimazaki, Tetsutaro Sata, Noriko Nakajima Journal of neurovirology 2007 pols set
Crystal structures of clinically relevant Lys103Asn/Tyr181Cys double mutant HIV-1 reverse transcriptase in complexes with ATP and non-nucleoside inhibitor HBY 097. Kalyan Das, Stefan G Sarafianos, Arthur D Clark, Paul L Boyer, Stephen H Hughes, Edward Arnold Journal of molecular biology 2007 partial results
Nucleotide incorporation against 7,8-dihydro-8-oxoguanine is influenced by neighboring base sequences in TLS DNA polymerase reaction. Chinwei Yung, Tetsuya Suzuki, Yoji Okugawa, Asako Kawakami, David Loakes, Kazuo Negishi, Tomoe Negishi Nucleic Acids Symp Ser (Oxf) 2007 new
Mutagenic bypass of the butadiene-derived 2'-deoxyuridine adducts by polymerases eta and zeta. PriscillaH Fernandes, RStephen Lloyd Mutation research 2007 topics set
Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesis. Ranga N Venkatesan, Piper M Treuting, Evan D Fuller, Robert E Goldsby, Thomas H Norwood, Ted A Gooley, Warren C Ladiges, Bradley D Preston, Lawrence A Loeb Molecular and cellular biology 2007 partial results
Mammary carcinogenesis in transgenic mice expressing a dominant-negative mutant of DNA polymerase beta in their mammary glands. Liming Wang, Nandan Bhattacharyya, Thangaiyan Rabi, Li Wang, Sanjeev Banerjee Carcinogenesis 2007 new
Synthesis of AZTpSpCX2ppSA and AZTpSpCX2ppSAZT: hydrolysis-resistant potential inhibitors of the AZT excision reaction of HIV-1 RT. Qianwei Han, Stefan G Sarafianos, Edward Arnold, Michael A. Parniak, Barbara L Gaffney, Roger A Jones Organic letters 2007 pols set
A novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase delta. Sufang Zhang, Yanjiao Zhou, Sandra Trusa, Xiao Meng, Ernest Y C Lee, Marietta Y W T Lee The Journal of biological chemistry 2007 pols set
Mutational patterns associated with the 69 insertion complex in multi-drug-resistant HIV-1 reverse transcriptase that confer increased excision activity and high-level resistance to zidovudine. Clara E Cases-González, Sandra Franco, Miguel Angel Martínez, L Menéndez-Arias Journal of molecular biology 2007 topics set
Probing DNA polymerase-DNA interactions: examining the template strand in exonuclease complexes using 2-aminopurine fluorescence and acrylamide quenching. Dina Tleugabulova, Linda J Reha-Krantz Biochemistry 2007 complete
Specific interactions of three proliferating cell nuclear antigens with replication-related proteins in Aeropyrum pernix. Kaori Imamura, Kenzo Fukunaga, Yutaka Kawarabayasi, Yoshizumi Ishino Molecular microbiology 2007 topics set
Genomewide and biochemical analyses of DNA-binding activity of Cdc6/Orc1 and Mcm proteins in Pyrococcus sp. Fujihiko Matsunaga, Annie Glatigny, Marie-Hélène Mucchielli-Giorgi, Nicolas Agier, Hervé Delacroix, Laetitia Marisa, Patrice Durosay, Yoshizumi Ishino, Lawrence Aggerbeck, Patrick Forterre Nucleic acids research 2007 new
Identification, transcriptional and phylogenetic analysis of the DNA polymerase gene of Pieris rapae granulovirus. Ronghui Wen, Rong Ou, Baoshan Chen Virus genes 2007 new
Crystal structure of the GINS complex and functional insights into its role in DNA replication. Y Paul Chang, Ganggang Wang, Vladimir Bermudez, Jerard Hurwitz, Xiaojiang S Chen Proceedings of the National Academy of Sciences of the United States of America 2007 new
Role of the 5' --> 3' exonuclease and Klenow fragment of Escherichia coli DNA polymerase I in base mismatch repair. Masaru Imai, Yu-ichiro Tago, Makoto Ihara, Masakado Kawata, Kazuo Yamamoto Mol Genet Genomics 2007 pols set
Involvement of DNA polymerase mu in the repair of a specific subset of DNA double-strand breaks in mammalian cells. Jean-Pascal Capp, François Boudsocq, Anne-Gaelle Besnard, Bernard S Lopez, Christophe Cazaux, Jean-Sébastien Hoffmann, Yvan Canitrot Nucleic acids research 2007 new
An importin alpha/beta-recognized bipartite nuclear localization signal mediates targeting of the human herpes simplex virus type 1 DNA polymerase catalytic subunit pUL30 to the nucleus. Gualtiero Alvisi, Daniele Musiani, David A Jans, Alessandro Ripalti Biochemistry 2007 new
Solution structure of Domains IVa and V of the tau subunit of Escherichia coli DNA polymerase III and interaction with the alpha subunit. Xun-Cheng Su, Slobodan Jergic, Max A Keniry, Nicholas E Dixon, Gottfried Otting Nucleic acids research 2007 topics set
Regulation of B family DNA polymerase fidelity by a conserved active site residue: characterization of M644W, M644L and M644F mutants of yeast DNA polymerase epsilon. Zachary F Pursell, Isabelle Isoz, Else-Britt Lundström, Erik Johansson, Thomas A Kunkel Nucleic acids research 2007 new
The roles of Tyr391 and Tyr619 in RB69 DNA polymerase replication fidelity. Agata Jacewicz, Karolina Makiela, Andrzej Kierzek, John W Drake, Anna Bebenek Journal of molecular biology 2007 complete
Study of interaction of XRCC1 with DNA and proteins of base excision repair by photoaffinity labeling technique. Zh K Nazarkina, Svetlana N Khodyreva, Stéphanie Marsin, J Pablo Radicella, Olga I Lavrik Biochemistry. Biokhimii͡a 2007 new
Mutations that decrease DNA binding of the processivity factor of the herpes simplex virus DNA polymerase reduce viral yield, alter the kinetics of viral DNA replication, and decrease the fidelity of DNA replication. Changying Jiang, Ying T Hwang, John C W Randell, Donald M Coen, Charles B C Hwang J Virol 2007 new
Role of Escherichia coli DNA polymerase I in conferring viability upon the dnaN159 mutant strain. Robert W Maul, Laurie H Sanders, James B Lim, Rosemary Benitez, Mark D Sutton J Bacteriol 2007 pols set
Werner syndrome protein interacts functionally with translesion DNA polymerases. Ashwini S Kamath-Loeb, Li Lan, Satoshi Nakajima, Akira Yasui, Lawrence A Loeb Proceedings of the National Academy of Sciences of the United States of America 2007 new
Structural insight into the substrate specificity of DNA Polymerase mu. Andrea F Moon, Miguel Garcia-Diaz, Katarzyna Bebenek, Bryan J Davis, Xuejun Zhong, Dale A Ramsden, Thomas A Kunkel, Lars C Pedersen Nature structural & molecular biology 2007 topics set
Chemical properties of fatty acid derivatives as inhibitors of DNA polymerases. Ryoichi Nakamura, Ryo Takeuchi, Kouji Kuramochi, Yoshiyuki Mizushina, Chisato Ishimaru, Yoichi Takakusagi, Masaharu Takemura, Susumu Kobayashi, Hiromi Yoshida, Fumio Sugawara, Kengo Sakaguchi Organic & biomolecular chemistry 2007 new
Increased flexibility enhances misincorporation: temperature effects on nucleotide incorporation opposite a bulky carcinogen-DNA adduct by a Y-family DNA polymerase. Rebecca A Perlow-Poehnelt, Ilya Likhterov, Liming Wang, David A Scicchitano, Nicholas E Geacintov, Suse Broyde The Journal of biological chemistry 2007 partial results
Mechanism of cell cycle arrest and apoptosis induction by conjugated eicosapentaenoic acid, which is a mammalian DNA polymerase and topoisomerase inhibitor. Yuko Yonezawa, Takahiko Hada, Keisuke Uryu, Tsuyoshi Tsuzuki, Kiyotaka Nakagawa, Teruo Miyazawa, Hiromi Yoshida, Yoshiyuki Mizushina International journal of oncology 2007 new
Mutations in human immunodeficiency virus type 1 RNase H primer grip enhance 3'-azido-3'-deoxythymidine resistance. Krista A Delviks-Frankenberry, Galina N Nikolenko, Rebekah Barr, Vinay K Pathak J Virol 2007 topics set
Genome-wide analysis of the core DNA replication machinery in the higher plants Arabidopsis and rice. Randall W Shultz, Vinaya M Tatineni, Linda Hanley-Bowdoin, William F Thompson Plant Physiol 2007 topics set
A water-mediated and substrate-assisted catalytic mechanism for Sulfolobus solfataricus DNA polymerase IV. Liming Wang, Xinyun Yu, Po Hu, Suse Broyde, Yongqing Zhang Journal of the American Chemical Society 2007 topics set
The DNA polymerase gamma Y955C disease variant associated with PEO and parkinsonism mediates the incorporation and translesion synthesis opposite 7,8-dihydro-8-oxo-2'-deoxyguanosine. Maria A Graziewicz, Rachelle J Bienstock, William C Copeland Human molecular genetics 2007 new
Sloppy bypass of an abasic lesion catalyzed by a Y-family DNA polymerase. Kevin A Fiala, Zucai Suo The Journal of biological chemistry 2007 topics set
Fluorescence of 2-aminopurine reveals rapid conformational changes in the RB69 DNA polymerase-primer/template complexes upon binding and incorporation of matched deoxynucleoside triphosphates. Haijiang Zhang, W Cao, E Zakharova, William H Konigsberg, E M De La Cruz Nucleic acids research 2007 complete
In vitro fidelity of the prototype primate foamy virus (PFV) RT compared to HIV-1 RT. Paul L Boyer, Carolyn R Stenbak, David Hoberman, Maxine L Linial, Stephen H Hughes Virology 2007 partial results
Early detection and quantification of lamivudine-resistant hepatitis B virus mutants by fluorescent biprobe hybridization assay in lamivudine-treated patients. Fumi Umeoka, Yoshiaki Iwasaki, Masayuki Matsumura, Akinobu Takaki, Haruhiko Kobashi, Masashi Tatsukawa, Hidenori Shiraha, Shin-ichi Fujioka, Kohsaku Sakaguchi, Yasushi Shiratori Journal of gastroenterology 2006 new
Mechanistic comparison of high-fidelity and error-prone DNA polymerases and ligases involved in DNA repair. Alexander K Showalter, Brandon J Lamarche, Marina Bakhtina, Mei-I Su, Kuo-Hsiang Tang, Ming-Daw Tsai Chem Rev 2006 pols set
Adenovirus mediated transduction of the human DNA polymerase eta cDNA. Keronninn Moreno Lima-Bessa, Vanessa Chiganças, Anne Stary, Patricia L Kannouche, Alain Sarasin, Melissa Gava Armelini, Jacqueline de Fátima Jacysyn, Gustavo P Amarante-Mendes, Marila Cordeiro-Stone, James E Cleaver, Carlos Frederico Martins Menck DNA repair 2006 complete Carlos Frederico Martins Menck*
2'-Deoxy-4'-C-ethynyl-2-fluoroadenosine: a nucleoside reverse transcriptase inhibitor with highly potent activity against all HIV-1 strains, favorable toxic profiles and stability in plasma. Hiroshi Ohrui, Satoru Kohgo, Hiroyuki Hayakawa, Eiichi N Kodama, Masao Matsuoka, Tomohiro Nakata, Hiroyuki Mitsuya Nucleic Acids Symp Ser (Oxf) 2006 partial results
Translesion synthesis across bulky N2-alkyl guanine DNA adducts by human DNA polymerase kappa. Jeong-Yun Choi, Karen C Angel, F Peter Guengerich The Journal of biological chemistry 2006 pols set
Synthetic analogues of the manzamenones and plakoridines which inhibit DNA polymerase. Jeremy R Doncaster, Laura L Etchells, Neil M Kershaw, Ryoichi Nakamura, Hazel Ryan, Ryo Takeuchi, Kengo Sakaguchi, Ali Sardarian, Roger C Whitehead Bioorganic & medicinal chemistry letters 2006 new
Mutation of Phe102 to Ser in the carboxyl terminal helix of Escherichia coli thioredoxin affects the stability and processivity of T7 DNA polymerase. Joyce Chiu, Daniel Tillett, Paul E March Proteins 2006 pols set
Interactions of carcinogen-bound DNA with individual DNA polymerases. F Peter Guengerich Chem Rev 2006 topics set
Environmental stress and lesion-bypass DNA polymerases. Takehiko Nohmi Annual review of microbiology 2006 topics set
Kinetic effect of a downstream strand and its 5'-terminal moieties on single nucleotide gap-filling synthesis catalyzed by human DNA polymerase lambda. Wade W Duym, Kevin A Fiala, Nikunj Bhatt, Zucai Suo The Journal of biological chemistry 2006 pols set
The Y-family DNA polymerase kappa (pol kappa) functions in mammalian nucleotide-excision repair. Tomoo Ogi, Alan R Lehmann Nat Cell Biol 2006 new
Dynamics of loading the Escherichia coli DNA polymerase processivity clamp. Linda B Bloom Crit Rev Biochem Mol Biol 2006 pols set
An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site. Deepak T Nair, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Structure (London, England : 1993) 2006 topics set
Arylthiopyrrole (AThP) derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors: synthesis, structure-activity relationships, and docking studies (part 2). Antonio Lavecchia, Roberta Costi, Marino Artico, Gaetano Miele, Ettore Novellino, Alberto Bergamini, Emmanuele Crespan, Giovanni Maga, Roberto Di Santo ChemMedChem 2006 pols set
Arylthiopyrrole (AThP) derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors: synthesis, structure-activity relationships, and docking studies (part 1). Roberto Di Santo, Roberta Costi, Marino Artico, Gaetano Miele, Antonio Lavecchia, Ettore Novellino, Alberto Bergamini, Reynel Cancio, Giovanni Maga ChemMedChem 2006 pols set
The plasmid RK2 replication initiator protein (TrfA) binds to the sliding clamp beta subunit of DNA polymerase III: implication for the toxicity of a peptide derived from the amino-terminal portion of 33-kilodalton TrfA. Kritaya Kongsuwan, Peter Josh, Marc J Picault, Gene Wijffels, Brian P Dalrymple J Bacteriol 2006 new
Design, synthesis, biological evaluation, and molecular modeling studies of TIBO-like cyclic sulfones as non-nucleoside HIV-1 reverse transcriptase inhibitors. Roberto Di Santo, Roberta Costi, Marino Artico, Rino Ragno, Antonio Lavecchia, Ettore Novellino, Enrico Gavuzzo, Francesco La Torre, Roberto Cirilli, Reynel Cancio, Giovanni Maga ChemMedChem 2006 pols set
Antiretroviral nucleosides, deoxynucleotide carrier and mitochondrial DNA: evidence supporting the DNA pol gamma hypothesis. William Lewis, James J Kohler, Seyed H Hosseini, Chad P Haase, William C Copeland, Rachelle J Bienstock, Tomika Ludaway, Jamie McNaught, Rodney Russ, Tami Stuart, Robert Santoianni AIDS (London, England) 2006 new
Hoogsteen base pair formation promotes synthesis opposite the 1,N6-ethenodeoxyadenosine lesion by human DNA polymerase iota. Deepak T Nair, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Nature structural & molecular biology 2006 topics set
Catechin conjugated with fatty acid inhibits DNA polymerase and angiogenesis. Kiminori Matsubara, Akiko Saito, Akira Tanaka, Noriyuki Nakajima, Reiko Akagi, Masaharu Mori, Yoshiyuki Mizushina DNA Cell Biol 2006 new
Inhibitory effect of monogalactosyldiacylglycerol, extracted from spinach using supercritical CO2, on mammalian DNA polymerase activity. Hiroshi Iijima, Keiichi Musumi, Takahiko Hada, Naoki Maeda, Yuko Yonezawa, Hiromi Yoshida, Yoshiyuki Mizushina J Agric Food Chem 2006 pols set
Increased susceptibility to UV-induced skin carcinogenesis in polymerase eta-deficient mice. Qingcong Lin, Alan B Clark, Scott D McCulloch, Tao Yuan, Roderick T Bronson, Thomas A Kunkel, Raju Kucherlapati Cancer research 2006 new
Early-onset familial parkinsonism due to POLG mutations. Guido Davidzon, Paul Greene, Michelangelo Mancuso, Kevin J Klos, J Eric Ahlskog, Michio Hirano, Salvatore DiMauro Annals of neurology 2006 pols set
Arabidopsis TEBICHI, with helicase and DNA polymerase domains, is required for regulated cell division and differentiation in meristems. Soichi Inagaki, Takamasa Suzuki, Masa-aki Ohto, Hiroko Urawa, Takashi Horiuchi, Kenzo Nakamura, Atsushi Morikami Plant Cell 2006 pols set
Raloxifene increases proliferation and up-regulates telomerase activity in human umbilical vein endothelial cells. Masakazu Doshida, Masahide Ohmichi, Seiji Tsutsumi, Jun Kawagoe, Tomosaburo Takahashi, Botao Du, Akiko Mori-Abe, Tsuyoshi Ohta, Maki Saitoh-Sekiguchi, Kazuhiro Takahashi, Hirohisa Kurachi The Journal of biological chemistry 2006 new
Inhibitory effect of sulfoquinovosyl diacylglycerol on prokaryotic DNA polymerase I activity and cell growth of Escherichia coli. Tomoyuki Furukawa, Masayuki Nishida, Takahiko Hada, Kouji Kuramochi, Fumio Sugawara, Susumu Kobayashi, Hiroshi Iijima, Hiroaki Shimada, Hiromi Yoshida, Yoshiyuki Mizushina J Oleo Sci 2006 pols set
Thermostable DNA polymerases can perform translesion synthesis using 8-oxoguanine and tetrahydrofuran-containing DNA templates. Ekaterina A Belousova, Nadejda I Rechkunova, Olga I Lavrik Biochimica et biophysica acta 2006 new
Role of hoogsteen edge hydrogen bonding at template purines in nucleotide incorporation by human DNA polymerase iota. Robert E Johnson, Lajos Haracska, Louise Prakash, Satya Prakash Molecular and cellular biology 2006 pols set
Mutator phenotypes caused by substitution at a conserved motif A residue in eukaryotic DNA polymerase delta. Ranga N Venkatesan, Jessica J Hsu, Nicole A Lawrence, Bradley D Preston, Lawrence A Loeb The Journal of biological chemistry 2006 new
Characterization of a second proliferating cell nuclear antigen (PCNA2) from Drosophila melanogaster. Tatsushi Ruike, Ryo Takeuchi, Kei-ichi Takata, Masahiko Oshige, Nobuyuki Kasai, Kaori Shimanouchi, Yoshihiro Kanai, Ryoichi Nakamura, Fumio Sugawara, Kengo Sakaguchi The FEBS journal 2006 new
Functional roles of p12, the fourth subunit of human DNA polymerase delta. Hao Li, Bin Xie, Yanjiao Zhou, Amal A Rahmeh, Sandra Trusa, Sufang Zhang, Yan Gao, Ernest Y C Lee, Marietta Y W T Lee The Journal of biological chemistry 2006 pols set
DNA polymerase iota-dependent translesion replication of uracil containing cyclobutane pyrimidine dimers. Alexandra Vaisman, Kohei Takasawa, Shigenori Iwai, Roger Woodgate DNA repair 2006 new
A coproofreading Zn(2+)-dependent exonuclease within a bacterial replicase. Natalie M Stano, Joe Chen, Charles S McHenry Nature structural & molecular biology 2006 new
Cloning, expression, and functional characterization of the equine herpesvirus 1 DNA polymerase and its accessory subunit. Arianna Loregian, Alessandro Case, Enrico Cancellotti, Carlo Valente, Howard S Marsden, Giorgio Palù J Virol 2006 topics set
The p66 and p12 subunits of DNA polymerase delta are modified by ubiquitin and ubiquitin-like proteins. Geng Liu, Emma Warbrick Biochem Biophys Res Commun 2006 complete Emma Warbrick*
Loss of DNA polymerase zeta causes chromosomal instability in mammalian cells. John P Wittschieben, Shalini C Reshmi, Susanne M Gollin, Richard D Wood Cancer research 2006 new
Human parechovirus infections in Dutch children and the association between serotype and disease severity. K S M Benschop, J Schinkel, R P Minnaar, D Pajkrt, L Spanjerberg, H C Kraakman, Ben Berkhout, H L Zaaijer, M G H M Beld, K C Wolthers Clin Infect Dis 2006 new
Magnesium-induced assembly of a complete DNA polymerase catalytic complex. Vinod K Batra, William A Beard, David D Shock, Joseph M Krahn, Lars C Pedersen, Samuel H Wilson Structure (London, England : 1993) 2006 complete Samuel H Wilson*
An unnatural hydrophobic base pair system: site-specific incorporation of nucleotide analogs into DNA and RNA. Ichiro Hirao, Michiko Kimoto, Tsuneo Mitsui, Tsuyoshi Fujiwara, Rie Kawai, Akira Sato, Yoko Harada, Shigeyuki Yokoyama Nature methods 2006 topics set
[Association between high activity of DNA polymerase iota and the development of human uveal melanoma]. Leonid V Gening, E E Grishina, A N Petrochenkov, Vyacheslav Z Tarantul Genetika 2006 new
Roles of DNA polymerases in replication, repair, and recombination in eukaryotes. Youri I Pavlov, Polina V Shcherbakova, Igor B Rogozin Int Rev Cytol 2006 new
Indolyl aryl sulphones as HIV-1 non-nucleoside reverse transcriptase inhibitors: synthesis, biological evaluation and binding mode studies of new derivatives at indole-2-carboxamide. Gabriella De Martino, Giuseppe La Regina, Rino Ragno, Antonio Coluccia, Alberto Bergamini, Chiara Ciaprini, Anna Sinistro, Giovanni Maga, Emmanuele Crespan, Marino Artico, Romano Silvestri Antiviral chemistry & chemotherapy 2006 pols set
The influence of the DNA polymerase gamma accessory subunit on base excision repair by the catalytic subunit. Kevin G Pinz, Daniel F Bogenhagen DNA repair 2006 pols set
[Advances of study on human translesion synthesis DNA polymerase eta]. Gong-hua Hu, Zhi-xiong Zhuang Wei Sheng Yan Jiu 2006 new
DNA polymerase X from Deinococcus radiodurans possesses a structure-modulated 3'-->5' exonuclease activity involved in radioresistance. Melanie Blasius, Igor V Shevelev, Edmond Jolivet, Suzanne Sommer, Ulrich Hübscher Molecular microbiology 2006 pols set
Structure of the theta subunit of Escherichia coli DNA polymerase III in complex with the epsilon subunit. Max A Keniry, Ah Young Park, Elisabeth A Owen, Samir M Hamdan, Guido Pintacuda, Gottfried Otting, Nicholas E Dixon J Bacteriol 2006 topics set
A role for replication repair in the genesis of templated mutations. Gary E Schultz, Geraldine T Carver, John W Drake Journal of molecular biology 2006 complete
UV-induced RPA phosphorylation is increased in the absence of DNA polymerase eta and requires DNA-PK. Séverine Cruet-Hennequart, Seamus Coyne, Macdara T Glynn, Gregory G Oakley, Michael P Carty DNA repair 2006 complete Michael P Carty*
Effect of ultrasound on DNA polymerase reactions: monitoring on a 27-MHz quartz crystal microbalance. Yu Hoshino, Takayoshi Kawasaki, Yoshio Okahata Biomacromolecules 2006 new
A new paradigm for DNA polymerase specificity. Yu-Chih Tsai, Kenneth A Johnson Biochemistry 2006 pols set
Incorporation and replication of 8-oxo-deoxyguanosine by the human mitochondrial DNA polymerase. Jeremiah W Hanes, David M Thal, Kenneth A Johnson The Journal of biological chemistry 2006 new
Efficient and high fidelity incorporation of dCTP opposite 7,8-dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA polymerase Dpo4. Hong Zang, Adriana Irimia, Jeong-Yun Choi, Karen C Angel, Lioudmila V Loukachevitch, Martin Egli, F Peter Guengerich The Journal of biological chemistry 2006 topics set
Crystal structure of the catalytic alpha subunit of E. coli replicative DNA polymerase III. Meindert H Lamers, Roxana E Georgescu, Sang-Gyu Lee, Mike E O'Donnell, John Kuriyan Cell 2006 topics set
Mutations in DNA polymerase eta are not detected in squamous cell carcinoma of the skin. Eitan Glick, Lisa M White, Nathan A Elliott, Daniel Berg, Nancy B Kiviat, Lawrence A Loeb Int J Cancer 2006 new
Real-time monitoring of DNA polymerase activity using molecular beacon. Changbei Ma, Zhiwen Tang, Kemin Wang, Weihong Tan, Jun Li, Wei Li, Zhongjie Li, Xiaohai Yang, Huimin Li, Lingfeng Liu Anal Biochem 2006 complete Kemin Wang*
Estimation of DNA polymerase for improvement of rolling circle amplification. Takeo Yoshimura, Saori Arikado, Shokichi Ohuchi Nucleic Acids Symp Ser (Oxf) 2006 new
Energy analysis of chemistry for correct insertion by DNA polymerase beta. Ping Lin, Lars C Pedersen, Vinod K Batra, William A Beard, Samuel H Wilson, Lee G Pedersen Proceedings of the National Academy of Sciences of the United States of America 2006 topics set
Fidelity of the human mitochondrial DNA polymerase. Harold R Lee, Kenneth A Johnson The Journal of biological chemistry 2006 new
A dynamic model for replication protein A (RPA) function in DNA processing pathways. Ellen Fanning, Vitaly Klimovich, Andrew R Nager Nucleic acids research 2006 topics set
[A new method of molecular marker--RMAPD]. Xian-Yong Lan, Hong Chen, Yong-De Zhang, Wei-Bin Sun, Chu-Zhao Lei Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji 2006 new
In silico studies of the African swine fever virus DNA polymerase X support an induced-fit mechanism. Benedetta A Sampoli Benítez, Karunesh Arora, Tamar Schlick Biophys J 2006 new
Mitochondrial DNA polymerase-gamma and human disease. Gavin Hudson, Patrick F Chinnery Hum Mol Genet 2006 new
The DNA polymerase activity of Pol epsilon holoenzyme is required for rapid and efficient chromosomal DNA replication in Xenopus egg extracts. Koh Shikata, Taro Sasa-Masuda, Yukiko Okuno, Shou Waga, Akio Sugino BMC Biochem 2006 new
DNA polymerase-beta is expressed early in neurons of Alzheimer's disease brain and is loaded into DNA replication forks in neurons challenged with beta-amyloid. Agata Copani, Jeroen J M Hoozemans, Filippo Caraci, Marco Calafiore, Elise S Van Haastert, Robert Veerhuis, Annemieke J M Rozemuller, Eleonora Aronica, Maria Angela Sortino, Ferdinando Nicoletti J Neurosci 2006 new
The phi29 DNA polymerase:protein-primer structure suggests a model for the initiation to elongation transition. Satwik Kamtekar, Andrea J Berman, Jianhong Wang, José María Lázaro, Miguel de Vega, Luis Blanco, Margarita Salas, Thomas A Steitz The EMBO journal 2006 topics set
High prevalence of the K65R mutation in human immunodeficiency virus type 1 subtype C isolates from infected patients in Botswana treated with didanosine-based regimens. Florence Doualla-Bell, Ava Avalos, Bluma G Brenner, Tendani Gaolathe, Madisa Mine, Simani Gaseitsiwe, Maureen Oliveira, Daniella Moisi, Ndwapi Ndwapi, Howard Moffat, Max Essex, Mark A. Wainberg Antimicrobial agents and chemotherapy 2006 new
The structure of T. aquaticus DNA polymerase III is distinct from eukaryotic replicative DNA polymerases. Scott Bailey, Richard A Wing, Thomas A Steitz Cell 2006 topics set
A false note of DNA polymerase iota in the choir of genome caretakers in mammals. Leonid V Gening, Alena V Makarova, A M Malashenko, Vyacheslav Z Tarantul Biochemistry (Mosc) 2006 new
DNA polymerase eta, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates the DNA damage checkpoint and p53 activation. Gang Liu, Xinbin Chen Molecular and cellular biology 2006 new
Mechanism of nucleotide incorporation in DNA polymerase beta. Ravi Radhakrishnan Biochem Biophys Res Commun 2006 topics set
Efficiency of exonucleolytic action of apurinic/apyrimidinic endonuclease 1 towards matched and mismatched dNMP at the 3' terminus of different oligomeric DNA structures correlates with thermal stability of DNA duplexes. Nadezhda S Dyrkheeva, Alexander A Lomzov, Dmitriy V Pyshnyi, Svetlana N Khodyreva, Olga I Lavrik Biochimica et biophysica acta 2006 new
3'-5' exonuclease activity of human apurinic/apyrimidinic endonuclease 1 towards DNAs containing dNMP and their modified analogs at the 3 end of single strand DNA break. Nadezhda S Dyrkheeva, Svetlana N Khodyreva, Maria V Sukhanova, I V Safronov, Sergey V Dezhurov, Olga I Lavrik Biochemistry. Biokhimii͡a 2006 new
Poleta, Polzeta and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cells. Bo Zhao, Jianhong Wang, Nicholas E Geacintov, Zhengqiang Wang Nucleic acids research 2006 topics set
Human replication protein A can suppress the intrinsic in vitro mutator phenotype of human DNA polymerase lambda. Giovanni Maga, Igor V Shevelev, Giuseppe Villani, Silvio Spadari, Ulrich Hübscher Nucleic acids research 2006 pols set
Crystal structure of intein homing endonuclease II encoded in DNA polymerase gene from hyperthermophilic archaeon Thermococcus kodakaraensis strain KOD1. Hiroyoshi Matsumura, Hitomi Takahashi, Tsuyoshi Inoue, Takahiko Yamamoto, Hiroshi Hashimoto, Motomu Nishioka, Shinsuke Fujiwara, Masahiro Takagi, Tadayuki Imanaka, Yasushi Kai Proteins 2006 new
Novel non-nucleobase inhibitors of Staphylococcus aureus DNA polymerase IIIC. Yannick Rose, Stéphane Ciblat, Ranga Reddy, Adam C Belley, Evelyne Dietrich, Dario Lehoux, Geoffrey A McKay, Hugo Poirier, Adel Rafai Far, Daniel Delorme Bioorganic & medicinal chemistry letters 2006 new
A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase. Li Fan, Sangbumn Kim, Carol L Farr, Kevin T Schaefer, Kathleen M Randolph, John A Tainer, Laurie S Kaguni Journal of molecular biology 2006 complete John A Tainer*
Lack of association between infection with a novel human coronavirus (HCoV), HCoV-NH, and Kawasaki disease in Taiwan. Luan-Yin Chang, Bor-Luen Chiang, Chuan-Liang Kao, Mei-Hwan Wu, Pei-Jer Chen, Ben Berkhout, Hui-Ching Yang, Li-Min Huang J Infect Dis 2006 new
[The value of magnifying endoscopy combined with human telomerase reverse transcriptase in diagnosing precancerous gastric lesions]. Xue-feng Lu, Zun-song Wang, Yong-chang Li, Jin-dong Fu Zhonghua nei ke za zhi [Chinese journal of internal medicine] 2006 new
A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis. Raquel Juárez, José F Ruiz, Stephanie A Nick McElhinny, Dale A Ramsden, Luis Blanco Nucleic acids research 2006 pols set
Structure of DNA polymerase beta with a benzo[c]phenanthrene diol epoxide-adducted template exhibits mutagenic features. Vinod K Batra, David D Shock, Rajendra Prasad, William A Beard, Esther W Hou, Lars C Pedersen, Jane M Sayer, Haruhiko Yagi, Subodh Kumar, Donald M Jerina, Samuel H Wilson Proceedings of the National Academy of Sciences of the United States of America 2006 topics set
HIV-1 subtype C viruses rapidly develop K65R resistance to tenofovir in cell culture. Bluma G Brenner, Maureen Oliveira, Florence Doualla-Bell, Daniela D Moisi, Michel L Ntemgwa, Fernando A Frankel, Max Essex, Mark A. Wainberg AIDS (London, England) 2006 new
Functional evidence for a small and rigid active site in a high fidelity DNA polymerase: probing T7 DNA polymerase with variably sized base pairs. Tae Woo Kim, Luis G Brieba, Tom Ellenberger, Eric T Kool The Journal of biological chemistry 2006 topics set
DNA polymerase epsilon associates with the elongating form of RNA polymerase II and nascent transcripts. Anna K Rytkönen, Tomi Hillukkala, Markku Vaara, Miiko Sokka, Maarit Jokela, Raija Sormunen, Heinz Peter Nasheuer, Tamar Nethanel, Gabriel Kaufmann, Helmut Pospiech, Juhani E Syväoja FEBS J 2006 partial results
Homology modeling of four Y-family, lesion-bypass DNA polymerases: the case that E. coli Pol IV and human Pol kappa are orthologs, and E. coli Pol V and human Pol eta are orthologs. Chiu Hong Lee, Sushil Chandani, Edward L Loechler J Mol Graph Model 2006 topics set
High-throughput screening of RNA polymerase inhibitors using a fluorescent UTP analog. Jyothi Bhat, Rajendra Rane, Suresh M Solapure, Dhiman Sarkar, Umender Sharma, M N Harish, Sarah Lamb, Darren Plant, Peter Alcock, Steve Peters, Shubhada Barde, Raman K Roy J Biomol Screen 2006 topics set
Indolopyridones inhibit human immunodeficiency virus reverse transcriptase with a novel mechanism of action. Dirk Jochmans, Jérôme Deval, Bart Kesteleyn, Herwig Van Marck, Eva Bettens, Inky De Baere, Pascale Dehertogh, Tania Ivens, Marcia Van Ginderen, Bertrand Van Schoubroeck, Maryam Ehteshami, Piet Wigerinck, Matthias Götte, Kurt Hertogs J Virol 2006 partial results
The replication factor C clamp loader requires arginine finger sensors to drive DNA binding and proliferating cell nuclear antigen loading. Aaron Johnson, Nina Y Yao, Gregory D Bowman, John Kuriyan, Mike E O'Donnell The Journal of biological chemistry 2006 topics set
The structural basis for the mutagenicity of O(6)-methyl-guanine lesions. Joshua J Warren, Lawrence J Forsberg, Lorena S Beese Proceedings of the National Academy of Sciences of the United States of America 2006 topics set
SANDO: two novel mutations in POLG1 gene. Miguel Fernandes Gago, M J Rosas, Joana Guimarães, Mariana Ferreira, Laura Vilarinho, Lígia Castro, Stirling Carpenter Neuromuscular disorders : NMD 2006 pols set
Specificity of replicative and SOS-inducible DNA polymerases in frameshift mutagenesis: mutability of Salmonella typhimurium strains overexpressing SOS-inducible DNA polymerases to 30 chemical mutagens. Keiko Matsui, Masami Yamada, Masaru Imai, Kazuo Yamamoto, Takehiko Nohmi DNA repair 2006 pols set
Involvement of Y-family DNA polymerases in mutagenesis caused by oxidized nucleotides in Escherichia coli. Masami Yamada, Tatsuo Nunoshiba, Masatomi Shimizu, Petr Gruz, Hiroyuki Kamiya, Hideyoshi Harashima, Takehiko Nohmi Journal of bacteriology 2006 pols set
Human enhancer of rudimentary is a molecular partner of PDIP46/SKAR, a protein interacting with DNA polymerase delta and S6K1 and regulating cell growth. Amelia Smyk, Magdalena Szuminska, Katarzyna A Uniewicz, Lee M Graves, Piotr Kozlowski FEBS J 2006 new
Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase. Steven A Jacobs, Elaine R Podell, Thomas R Cech Nature structural & molecular biology 2006 partial results
Selective excision of chain-terminating nucleotides by HIV-1 reverse transcriptase with phosphonoformate as substrate. Carlos Cruchaga, Elena Ansó, Ana Rouzaut, Juan J Martínez-Irujo The Journal of biological chemistry 2006 new
A method to select for mutator DNA polymerase deltas in Saccharomyces cerevisiae. Kelly M Murphy, Hariyanto Darmawan, Amy Schultz, Elizabeth Fidalgo da Silva, Linda J Reha-Krantz Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2006 new
DNA polymerases and human diseases. Joann B Sweasy, Julia M Lauper, Kristin A Eckert Radiat Res 2006 new
The level of reverse transcriptase (RT) in human immunodeficiency virus type 1 particles affects susceptibility to nonnucleoside RT inhibitors but not to lamivudine. Zandrea Ambrose, John G Julias, Paul L Boyer, Vineet N Kewalramani, Stephen H Hughes Journal of virology 2006 pols set
Effects of a modified dye-labeled nucleotide spacer arm on incorporation by thermophilic DNA polymerases. Christopher Lacenere, Meil K Garg, Brian M Stoltz, Stephen R Quake Nucleosides, nucleotides & nucleic acids 2006 topics set
Purification and characterization of Escherichia coli DNA polymerase V. Katharina Schlacher, Qingfei Jiang, Roger Woodgate, Myron F Goodman Methods in enzymology 2006 pols set
Wanderings of a DNA enzymologist: from DNA polymerase to viral latency. IRobert Lehman Annual review of biochemistry 2006 new
[Construction of prokaryotic expression plasmid pET15b-PEP-1-CAT and expression and purification of PEP-1-CAT fusion protein]. Ling-ling Yao, Jia-ning Wang, Yong-zhang Huang, Ling-yun Guo Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2006 new
Regulation of replication protein A functions in DNA mismatch repair by phosphorylation. Shuangli Guo, Yongqing Zhang, Fenghua Yuan, Yin Gao, Liya Gu, Isaac Wong, Guo-Min Li The Journal of biological chemistry 2006 new
Determination of lysine pK values using [5-13C]lysine: application to the lyase domain of DNA Pol beta. Guanghua Gao, Rajendra Prasad, Siegfried N Lodwig, Clifford J Unkefer, William A Beard, Samuel H Wilson, Robert E London Journal of the American Chemical Society 2006 new
Human terminal deoxynucleotidyl transferases as novel targets for anticancer chemotherapy. Roberto Di Santo, Giovanni Maga Current medicinal chemistry 2006 new
The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase beta. Jeanine A Harrigan, David M Wilson, Rajendra Prasad, Patricia L Opresko, Gad Beck, Alfred May, Samuel H Wilson, Vilhelm A Bohr Nucleic acids research 2006 new
Novel thermostable Y-family polymerases: applications for the PCR amplification of damaged or ancient DNAs. John P McDonald, Ashley Hall, Didier Gasparutto, Jean Cadet, Jack Ballantyne, Roger Woodgate Nucleic acids research 2006 pols set
Complex formation with Rev1 enhances the proficiency of Saccharomyces cerevisiae DNA polymerase zeta for mismatch extension and for extension opposite from DNA lesions. Narottam Acharya, Robert E Johnson, Satya Prakash, Louise Prakash Molecular and cellular biology 2006 pols set
Recent progress in the design of small molecule inhibitors of HIV RNase H. Klaus Klumpp, Tara Mirzadegan Curr Pharm Des 2006 new
Is base excision repair a tumor suppressor mechanism? Joann B Sweasy, Tieming Lang, Daniel Dimaio Cell cycle (Georgetown, Tex.) 2006 new
Evaluation of a multiple-cycle, recombinant virus, growth competition assay that uses flow cytometry to measure replication efficiency of human immunodeficiency virus type 1 in cell culture. Carrie Dykes, Jiong Wang, Xia Jin, Vicente Planelles, Dong Sung An, Amanda Tallo, Yangxin Huang, Hulin Wu, Lisa M Demeter Journal of clinical microbiology 2006 pols set
The HIV-1 reverse transcriptase mutants G190S and G190A, which confer resistance to non-nucleoside reverse transcriptase inhibitors, demonstrate reductions in RNase H activity and DNA synthesis from tRNA(Lys, 3) that correlate with reductions in replication efficiency. Jiong Wang, Carrie Dykes, R A Domaoal, Christine E Koval, R A Bambara, Lisa M Demeter Virology 2006 pols set
Relative replication fitness of efavirenz-resistant mutants of HIV-1: correlation with frequency during clinical therapy and evidence of compensation for the reduced fitness of K103N + L100I by the nucleoside resistance mutation L74V. Christine E Koval, Carrie Dykes, Jiong Wang, Lisa M Demeter Virology 2006 pols set
Ankyrin G overexpression in Hutchinson-Gilford progeria syndrome fibroblasts identified through biological filtering of expression profiles. Jian Wang, John F Robinson, Caroline H O'Neil, Jane Y Edwards, Christina M Williams, Murray W Huff, J Geoffrey Pickering, Robert A Hegele Journal of human genetics 2006 new
Fluorescent analysis of translesion DNA synthesis by using a novel, non-natural nucleotide analogue. Irene Lee, Anthony J Berdis Chembiochem : a European journal of chemical biology 2006 topics set
Multiplexed DNA sequencing-by-synthesis. Sergei A Aksyonov, Michael Bittner, Linda B Bloom, Linda J Reha-Krantz, Ian R Gould, Mark A Hayes, Urban A Kiernan, Eric E Niederkofler, Vincent Pizziconi, Raul S Rivera, Daniel J B Williams, Peter Williams Anal Biochem 2006 complete
The checkpoint clamp activates Mec1 kinase during initiation of the DNA damage checkpoint. Jerzy Majka, Anita Niedziela-Majka, PeterMJ Burgers Molecular cell 2006 new
Modification of human immunodeficiency virus type 1 reverse transcriptase to target cells with elevated cellular dNTP concentrations. Varuni K Jamburuthugoda, Pauline Chugh, Baek Kim The Journal of biological chemistry 2006 new
Lagging strand replication proteins in genome stability and DNA repair. Marie L Rossi, Vandana Purohit, Patrick D Brandt, Robert A Bambara Chem Rev 2006 topics set
Identification of differently expressed genes in human colorectal adenocarcinoma. Yao Chen, Yi-Zeng Zhang, Zong-Guang Zhou, Gang Wang, Zeng-Ni Yi World journal of gastroenterology : WJG 2006 new
Evidence that errors made by DNA polymerase alpha are corrected by DNA polymerase delta. Youri I Pavlov, C Frahm, Stephanie A Nick McElhinny, Atsuko Niimi, Motoshi Suzuki, Thomas A Kunkel Current biology : CB 2006 new
Human DNA polymerase kappa forms nonproductive complexes with matched primer termini but not with mismatched primer termini. Karissa D Carlson, Robert E Johnson, Louise Prakash, Satya Prakash, M Todd Washington Proceedings of the National Academy of Sciences of the United States of America 2006 complete M Todd Washington*
Why do HIV-1 and HIV-2 use different pathways to develop AZT resistance? Paul L Boyer, Stefan G Sarafianos, Patrick K Clark, Edward Arnold, Stephen H Hughes PLoS Pathog 2006 topics set
Structure and mechanism of DNA polymerase Beta. William A Beard, Samuel H Wilson Chem Rev 2006 topics set
Removal of contaminating TEM-la beta-lactamase gene from commercial Taq DNA polymerase. Jae Seok Song, Jung Hun Lee, Jung-Hyun Lee, Byeong Chul Jeong, Won-Keun Lee, Sang Hee Lee J Microbiol 2006 pols set
Effect of molecular crowding on DNA polymerase activity. Yoshiharu Sasaki, Daisuke Miyoshi, Naoki Sugimoto Biotechnol J 2006 new
Drosophila DNA polymerase zeta interacts with recombination repair protein 1, the Drosophila homologue of human abasic endonuclease 1. Ryo Takeuchi, Tatsushi Ruike, Ryo-ichi Nakamura, Kaori Shimanouchi, Yoshihiro Kanai, Yoko Abe, Ayumi Ihara, Kengo Sakaguchi The Journal of biological chemistry 2006 new
Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138. Jingshan Ren, Charles E Nichols, Anna Stamp, Phillip P Chamberlain, Robert G Ferris, Kurt L Weaver, Steven A Short, David K Stammers FEBS J 2006 partial results
The K65R reverse transcriptase mutation in HIV-1 reverses the excision phenotype of zidovudine resistance mutations. Kirsten L White, James M Chen, Joy Y Feng, Nicolas A Margot, John K Ly, Adrian S Ray, Holly L Macarthur, Martin J McDermott, S Swaminathan, Michael D Miller Antivir Ther 2006 topics set
Replication past a trans-4-hydroxynonenal minor-groove adduct by the sequential action of human DNA polymerases iota and kappa. William T Wolfle, Robert E Johnson, Irina G Minko, R Stephen Lloyd, Satya Prakash, Louise Prakash Molecular and cellular biology 2006 pols set
Accumulation of FFA-1, the Xenopus homolog of Werner helicase, and DNA polymerase delta on chromatin in response to replication fork arrest. Noriko Sasakawa, Tomoyuki Fukui, Shou Waga J Biochem 2006 new
Dimerization inhibitors of HIV-1 reverse transcriptase, protease and integrase: a single mode of inhibition for the three HIV enzymes? María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez, Federico Gago Antiviral research 2006 pols set
Development of a high-throughput membrane-array method for molecular diagnosis of circulating tumor cells in patients with gastric cancers. Chan-Hang Wu, Shiu-Ru Lin, Fang-Jung Yu, Deng-Chyang Wu, Yong-Sang Pan, Jan-Sing Hsieh, Sung-Yu Huang, Jaw-Yuan Wang International journal of cancer. Journal international du cancer 2006 new
RPA and PCNA suppress formation of large deletion errors by yeast DNA polymerase delta. John M Fortune, Carrie M W Stith, Grace E Kissling, Peter M J Burgers, Thomas A Kunkel Nucleic acids research 2006 new
Synthesis and anti-HIV activity of new alkenyldiarylmethane (ADAM) non-nucleoside reverse transcriptase inhibitors (NNRTIs) incorporating benzoxazolone and benzisoxazole rings. Bo-Liang Deng, Matthew D Cullen, Zhigang Zhou, Tracy L Hartman, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Phillip E Fanwick, Mark Cushman Bioorganic & medicinal chemistry 2006 pols set
Enhanced antitumor effect against human telomerase reverse transcriptase (hTERT) by vaccination with chemotactic-hTERT gene-modified tumor cell and the combination with anti-4-1BB monoclonal antibodies. Xiaoyan Lin, Chunxia Zhou, Shengdian Wang, Dongmei Wang, Wenbo Ma, Xiao Liang, Chen Lin, Zhengqiang Wang, Jinming Li, Sujuan Guo, Yongqing Zhang, Shuren Zhang International journal of cancer. Journal international du cancer 2006 new
Antiviral properties of new arylsulfone derivatives with activity against human betaherpesviruses. Lieve Naesens, Chad E Stephens, Graciela Andrei, Arianna Loregian, Leen De Bolle, Robert Snoeck, J Walter Sowell, Erik De Clercq Antiviral research 2006 new
Immortalization of normal human cytotrophoblast cells by reconstitution of telomeric reverse transcriptase activity. Yan-ling Wang, Wei Qiu, Hui-chen Feng, Yu-xia Li, Lin-zhi Zhuang, Zhengqiang Wang, Yu Liu, Jin-qiu Zhou, Deng-hong Zhang, George S W Tsao Molecular human reproduction 2006 new
Phenotypic resistance of resistant strains of HIV type-1 subtype B in China. Jinming Li, Jun-feng Lu, Hua-huang Dong, Zuo-Yi Bao, Si-Yang Liu, Han-Ping Li, Dao-Min Zhuang, Yong-Jian Liu, Hong Li, Zhengqiang Wang, Hao Wu, Jing-Yun Li Chinese medical journal 2006 new
UV-B radiation induces epithelial tumors in mice lacking DNA polymerase eta and mesenchymal tumors in mice deficient for DNA polymerase iota. Tsuyoshi Ohkumo, Yuji Kondo, Masayuki Yokoi, Tetsuya Tsukamoto, Ayumi Yamada, Taiki Sugimoto, Rie Kanao, Yujiro Higashi, Hisato Kondoh, Masae Tatematsu, Chikahide Masutani, Fumio Hanaoka Molecular and cellular biology 2006 new
Replacement of the metabolically labile methyl esters in the alkenyldiarylmethane series of non-nucleoside reverse transcriptase inhibitors with isoxazolone, isoxazole, oxazolone, or cyano substituents. Bo-Liang Deng, Tracy L Hartman, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman Journal of medicinal chemistry 2006 new
NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells. Aditi Das, Lee Wiederhold, John B Leppard, Padmini S Kedar, Rajendra Prasad, Huxian Wang, Istvan Boldogh, Feridoun Karimi-Busheri, Michael Weinfeld, Alan E Tomkinson, Samuel H Wilson, Sankar Mitra, Tapas K Hazra DNA repair 2006 new
Large fragment Bst DNA polymerase for whole genome amplification of DNA from formalin-fixed paraffin-embedded tissues. Sarit Aviel-Ronen, Chang Qi Zhu, Bradley P Coe, Ni Liu, Spencer K Watson, Wan L Lam, Ming Sound Tsao BMC Genomics 2006 pols set
Inhibition of DNA polymerase eta by oxetanocin derivatives. Shunji Izuta Nucleic Acids Symp Ser (Oxf) 2006 new
Cidofovir resistance in vaccinia virus is linked to diminished virulence in mice. Graciela Andrei, Don B Gammon, Pierre Fiten, Erik De Clercq, Ghislain Opdenakker, Robert Snoeck, David H Evans Journal of virology 2006 new
Nitroimidazoles, part 2: Synthesis, antiviral and antitumor activity of new 4-nitroimidazoles. Najim A Al-Masoudi, Yaseen A Al-Soud, Aris Kalogerakis, Christophe Pannecouque, Erik De Clercq Chemistry & biodiversity 2006 pols set
Nucleotide insertion opposite a cyclobutane pyrimidine dimer analogue caused from photoligation by a replicative DNA polymerase. Masayuki Ogino, Daisuke Okamura, Yoshinaga Yoshimura, Kenzo Fujimoto Nucleic Acids Symp Ser (Oxf) 2006 new
A new anti conformation for N-(deoxyguanosin-8-yl)-2-acetylaminofluorene (AAF-dG) allows Watson-Crick pairing in the Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4). Liming Wang, Suse Broyde Nucleic acids research 2006 topics set
The properties of steric gate mutants reveal different constraints within the active sites of Y-family and A-family DNA polymerases. Angela M DeLucia, Santanov Chaudhuri, Olga Potapova, Nigel D F Grindley, Catherine M Joyce The Journal of biological chemistry 2006 new
Yeast and human translesion DNA synthesis polymerases: expression, purification, and biochemical characterization. Robert E Johnson, Louise Prakash, Satya Prakash Methods in enzymology 2006 new
Ubiquitylation of yeast proliferating cell nuclear antigen and its implications for translesion DNA synthesis. Lajos Haracska, Ildiko Unk, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2006 new
Vaccinia virus uracil DNA glycosylase interacts with the A20 protein to form a heterodimeric processivity factor for the viral DNA polymerase. Eleni S Stanitsa, Lisa Arps, Paula Traktman The Journal of biological chemistry 2006 new
Synthesis and anti-HIV-1 and anti-HCMV activity of 1-substituted 3-(3,5-dimethylbenzyl)uracil derivatives. Tokumi Maruyama, Shigetada Kozai, Yosuke Demizu, Myriam Witvrouw, Christophe Pannecouque, Jan Balzarini, Robert Snoecks, Graciella Andrei, Erik De Clercq Chemical & pharmaceutical bulletin 2006 pols set
Kinetics of error generation in homologous B-family DNA polymerases. Matthew Hogg, Wendy Cooper, Linda J Reha-Krantz, Susan S Wallace Nucleic acids research 2006 partial results
A novel role of DNA polymerase eta in modulating cellular sensitivity to chemotherapeutic agents. Yih-Wen Chen, James E Cleaver, Fumio Hanaoka, Ching-fang Chang, Kai-Ming Chou Molecular cancer research : MCR 2006 new
Deoxyribophosphate lyase activity of mammalian endonuclease VIII-like proteins. Inga R Grin, Svetlana N Khodyreva, Georgy A Nevinsky, Dmitry O Zharkov FEBS letters 2006 new
Structure-activity relationships of [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]- 3'-spiro-5' '-(4' '-amino-1' ',2' '-oxathiole-2' ',2' '-dioxide)thymine derivatives as inhibitors of HIV-1 reverse transcriptase dimerization. Nicolas Sluis-Cremer, Noureddine Hamamouch, Ana San Félix, Sonsoles Velazquez, Jan Balzarini, María-José Camarasa Journal of medicinal chemistry 2006 pols set
Role of the second-largest subunit of DNA polymerase alpha in the interaction between the catalytic subunit and hyperphosphorylated retinoblastoma protein in late S phase. Masaharu Takemura, Shonen Yoshida, Tetsu Akiyama, Masatoshi Kitagawa, Yoshiji Yamada Biochimica et biophysica acta 2006 new
Conserved XPB core structure and motifs for DNA unwinding: implications for pathway selection of transcription or excision repair. Li Fan, Andrew S Arvai, Priscilla K Cooper, Shigenori Iwai, Fumio Hanaoka, John A Tainer Molecular cell 2006 new
Non-nucleoside HIV-1 reverse transcriptase inhibitors, Part 7. Synthesis, antiviral activity, and 3D-QSAR investigations of novel 6-(1-naphthoyl) HEPT analogues. Lei Ji, Fen-Er Chen, Xiao-Qing Feng, Erik De Clercq, Jan Balzarini, Christophe Pannecouque Chemical & pharmaceutical bulletin 2006 pols set
Cell cycle-specific changes in hTERT promoter activity in normal and cancerous cells in adenoviral gene therapy: a promising implication of telomerase-dependent targeted cancer gene therapy. Yoshiteru Murofushi, Satoshi Nagano, Junichi Kamizono, Tomosaburo Takahashi, Hisayoshi Fujiwara, Setsuro Komiya, Toyojiro Matsuishi, Ken-ichiro Kosai International journal of oncology 2006 new
A high-throughput, high-resolution strategy for the study of site-selective DNA binding agents: analysis of a "highly twisted" benzimidazole-diamidine. Kristie D Goodwin, Mark A Lewis, Farial A Tanious, Richard R Tidwell, W David Wilson, Millie M Georgiadis, Eric C Long Journal of the American Chemical Society 2006 topics set
Novel nonnucleoside inhibitors that select nucleoside inhibitor resistance mutations in human immunodeficiency virus type 1 reverse transcriptase. Zhijun Zhang, Michelle Walker, Wen Xu, Jae Hoon Shim, Jean-Luc Girardet, Robert K Hamatake, Zhi Hong Antimicrobial agents and chemotherapy 2006 pols set
Delivery of telomerase reverse transcriptase small interfering RNA in complex with positively charged single-walled carbon nanotubes suppresses tumor growth. Zhuohan Zhang, Xiaoying Yang, Yongqing Zhang, Bin Zeng, Shujing Wang, Tianhui Zhu, Richard B S Roden, Yongsheng Chen, Rongcun Yang Clinical cancer research : an official journal of the American Association for Cancer Research 2006 new
Normal hypermutation in antibody genes from congenic mice defective for DNA polymerase iota. Stella A Martomo, William W Yang, Alexandra Vaisman, Alex Maas, Masayuki Yokoi, Jan H Hoeijmakers, Fumio Hanaoka, Roger Woodgate, Patricia J Gearhart DNA repair 2006 new
Dominance of HIV-1 subtype CRF01_AE in sexually acquired cases leads to a new epidemic in Yunnan province of China. Yong Zhang, Lin Lu, Lei Ba, Li Liu, Li Yang, Manhong Jia, Haibo Wang, Qing Fang, Yuhua Shi, Wenyun Yan, Guangcai Chang, Linqi Zhang, David D Ho, Zhiwei Chen PLoS medicine 2006 new
A new POLG1 mutation with peo and severe axonal and demyelinating sensory-motor neuropathy. L Santoro, F Manganelli, R Lanzillo, A Tessa, F Barbieri, F Pierelli, G Di Giacinto, V Nigro, F M Santorelli Journal of neurology 2006 pols set
[The animal research of recombinant adenovirus controlled by human telomerase reverse transcriptase promoter in the treatment of human prostate cancer]. Yong Zhang, Jin-chun Qi, Wen-feng Lian, Wen-qing Cai, Wei Li, Kai-long Liu Zhonghua wai ke za zhi [Chinese journal of surgery] 2006 new
Multiple solutions to inefficient lesion bypass by T7 DNA polymerase. Scott D McCulloch, Thomas A Kunkel DNA repair 2006 pols set
Mitochondrial DNA integrity is not dependent on DNA polymerase-beta activity. Alexis B Hansen, Nicholas B Griner, Jon P Anderson, Greg C Kujoth, Tomas A Prolla, Lawrence A Loeb, Eitan Glick DNA repair 2006 new
Specific amino acid residues in the beta sliding clamp establish a DNA polymerase usage hierarchy in Escherichia coli. Mark D Sutton, Jill M Duzen DNA repair 2006 new
African swine fever virus protein pE296R is a DNA repair apurinic/apyrimidinic endonuclease required for virus growth in swine macrophages. Modesto Redrejo-Rodríguez, Ramón García-Escudero, Rafael J Yáñez-Muñoz, María L Salas, José Salas Journal of virology 2006 new
Selective anti-cytomegalovirus compounds discovered by screening for inhibitors of subunit interactions of the viral polymerase. Arianna Loregian, Donald M Coen Chemistry & biology 2006 new
Molecular diagnosis of Alpers syndrome. Khue V Nguyen, Farida S Sharief, Sherine S L Chan, William C Copeland, Robert K Naviaux Journal of hepatology 2006 pols set
Chlamydial DNA polymerase I can bypass lesions in vitro. Xipeng Liu, Jingli Hou, Jianhua Liu Biochem Biophys Res Commun 2006 new
Measuring the fidelity of translesion DNA synthesis. Scott D McCulloch, Thomas A Kunkel Methods in enzymology 2006 pols set
Mitochondrial and nuclear DNA defects in Saccharomyces cerevisiae with mutations in DNA polymerase gamma associated with progressive external ophthalmoplegia. Gregory R Stuart, Janine H Santos, Micheline K Strand, Bennett Van Houten, William C Copeland Hum Mol Genet 2006 pols set
Isolation of human Dna2 endonuclease and characterization of its enzymatic properties. Jeong-Hoon Kim, Hee-Dai Kim, Gi-Hyuck Ryu, Do-Hyung Kim, Jerard Hurwitz, Yeon-Soo Seo Nucleic acids research 2006 complete Yeon-Soo Seo*
Synergistic antiviral activity of acyclovir and vidarabine against herpes simplex virus types 1 and 2 and varicella-zoster virus. Mikiko Suzuki, Tomoko Okuda, Kimiyasu Shiraki Antiviral research 2006 new
Evolving thermostable reverse transcriptase activity in a DNA polymerase scaffold. Katharina B M Sauter, Andreas Marx Angewandte Chemie (International ed. in English) 2006 new
Involvement of phi29 DNA polymerase thumb subdomain in the proper coordination of synthesis and degradation during DNA replication. Patricia Pérez-Arnaiz, José María Lázaro, Margarita Salas, Miguel de Vega Nucleic acids research 2006 pols set
Visualizing polynucleotide polymerase machines at work. Thomas A Steitz The EMBO journal 2006 pols set
The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins. Xuejun Zhong, Parie Garg, Carrie M W Stith, Stephanie A Nick McElhinny, Grace E Kissling, Peter M J Burgers, Thomas A Kunkel Nucleic acids research 2006 new
Nucleotide-mimetic synthetic ligands for DNA-recognizing enzymes One-step purification of Pfu DNA polymerase. Sotirios Melissis, Nikolaos E Labrou, Yannis D Clonis J Chromatogr A 2006 pols set
Association of novel POLG mutations and multiple mitochondrial DNA deletions with variable clinical phenotypes in a Spanish population. Emiliano González-Vioque, Alberto Blázquez, Daniel Fernández-Moreira, Belén Bornstein, Juan Bautista, Javier Arpa, Carmen Navarro, Yolanda Campos, Miguel A Fernández-Moreno, Rafael Garesse, Joaquin Arenas, Miguel A Martín Archives of neurology 2006 pols set
The polymorphic polyglutamine repeat in the mitochondrial DNA polymerase gamma gene is not associated with oligozoospermia. A Brusco, C Michielotto, V Gatta, C Foresta, G Matullo, Massimo Zeviani, Gianfrancesco Ferrari, E Dragone, G Calabrese, M Rossato, L Stuppia, N Migone Journal of endocrinological investigation 2006 new
Involvement of novel human immunodeficiency virus type 1 reverse transcriptase mutations in the regulation of resistance to nucleoside inhibitors. Valentina Svicher, Tobias Sing, Maria Mercedes Santoro, Federica Forbici, Fátima Rodríguez-Barrios, Ada Bertoli, Niko Beerenwinkel, Maria Concetta Bellocchi, Federigo Gago, Antonella d'Arminio Monforte, Andrea Antinori, Thomas Lengauer, F Ceccherini-Silberstein, CF Perno Journal of virology 2006 pols set
POLG1 mutations associated with progressive encephalopathy in childhood. Gittan Kollberg, Ali-Reza Moslemi, Niklas Darin, Inger Nennesmo, Ingibjörg Bjarnadottir, Paul Uvebrant, Elisabeth Holme, Atle Melberg, Már Tulinius, Anders Oldfors Journal of neuropathology and experimental neurology 2006 pols set
Structural determinants of slippage-mediated mutations by human immunodeficiency virus type 1 reverse transcriptase. Monica E Hamburgh, Kenneth A Curr, Melissa Monaghan, Vasudev R Rao, Snehlata Tripathi, Bradley D Preston, Stefan G Sarafianos, Edward Arnold, Thomas Darden, Vinayaka R Prasad The Journal of biological chemistry 2006 pols set
Arginine methylation regulates DNA polymerase beta. Nazim El-Andaloussi, Taras Valovka, Magali Toueille, Roland Steinacher, Frauke Focke, Peter Gehrig, Marcela Covic, Paul O Hassa, Primo Schär, Ulrich Hübscher, Michael O Hottiger Molecular cell 2006 new
Vertebrate POLQ and POLbeta cooperate in base excision repair of oxidative DNA damage. Michio Yoshimura, Masaoki Kohzaki, Jun Nakamura, Kenjiro Asagoshi, Eiichiro Sonoda, Esther W Hou, Rajendra Prasad, Samuel H Wilson, Keizo Tano, Akira Yasui, Li Lan, Masayuki Seki, Richard D Wood, Hiroshi Arakawa, Jean-Marie Buerstedde, Helfrid Hochegger, Takashi Okada, Masahiro Hiraoka, Shunichi Takeda Molecular cell 2006 complete Shunichi Takeda*
Molecular analysis of polymerase gamma gene and mitochondrial polymorphism in fertile and subfertile men. T P Harris, K P Gomas, F Weir, A J Holyoake, P McHugh, Mei Wu, Y Sin, I L Sin, F Y T Sin International journal of andrology 2006 new
Effects of nucleotides and nucleotide analogue inhibitors of HIV-1 reverse transcriptase in a ratchet model of polymerase translocation. Matthias Götte Curr Pharm Des 2006 partial results
Optimization of the Y831C mutation detection in human DNA polymerase gamma by allelic discrimination assay. Katarzyna Stopińska, Tomasz Grzybowski, Boris A Malyarchuk, Miroslava V Derenko, Danuta Miścicka-Sliwka Acta biochimica Polonica 2006 pols set
Up-regulation of the fidelity of human DNA polymerase lambda by its non-enzymatic proline-rich domain. Kevin A Fiala, Wade W Duym, Jun Zhang, Zucai Suo The Journal of biological chemistry 2006 pols set
Phenotypic spectrum associated with mutations of the mitochondrial polymerase gamma gene. Rita Horvath, Gavin Hudson, Gianfrancesco Ferrari, Nancy Fütterer, Sofia Ahola, Eleonora Lamantea, Holger Prokisch, Hanns Lochmüller, Robert McFarland, V Ramesh, Thomas Klopstock, Peter Freisinger, Fabrizio Salvi, Johannes A Mayr, Rene Santer, Marketa Tesarova, Jiri Zeman, Bjarne Udd, Robert W Taylor, Douglass M Turnbull, Michael Hanna, Doreen Fialho, Anu Suomalainen, Massimo Zeviani, Patrick F Chinnery Brain : a journal of neurology 2006 pols set
POLG1, C10ORF2, and ANT1 mutations are uncommon in sporadic progressive external ophthalmoplegia with multiple mitochondrial DNA deletions. Gavin Hudson, M Deschauer, Robert W Taylor, M G Hanna, Doreen Fialho, Andrew M Schaefer, L-P He, E Blakely, Douglass M Turnbull, Patrick F Chinnery Neurology 2006 pols set
Structure of Saccharomyces cerevisiae DNA polymerase epsilon by cryo-electron microscopy. Francisco J Asturias, Iris K Cheung, Nasim Sabouri, Olga Chilkova, Daniel Wepplo, Erik Johansson Nature structural & molecular biology 2006 pols set
Functional characterization of highly processive protein-primed DNA polymerases from phages Nf and GA-1, endowed with a potent strand displacement capacity. Elisa Longás, Miguel de Vega, José María Lázaro, Margarita Salas Nucleic acids research 2006 partial results
The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replication. Kumiko Matsuno, Maya Kumano, Yumiko Kubota, Yoshitami Hashimoto, Haruhiko Takisawa Molecular and cellular biology 2006 new
Enhanced expression and activity of DNA polymerase beta in chronic myelogenous leukemia. Yvan Canitrot, Guy Laurent, Catherine Astarie-Dequeker, Christine Bordier, Christophe Cazaux, Jean-Sébastien Hoffmann Anticancer Res 2006 new
Genetic and chemical rescue of the Saccharomyces cerevisiae phenotype induced by mitochondrial DNA polymerase mutations associated with progressive external ophthalmoplegia in humans. Enrico Baruffini, Tiziana Lodi, Cristina Dallabona, Andrea Puglisi, Massimo Zeviani, Iliana Ferrero Human molecular genetics 2006 pols set
Single-strand-specific exonucleases prevent frameshift mutagenesis by suppressing SOS induction and the action of DinB/DNA polymerase IV in growing cells. Megan N Hersh, Liza D Morales, Kimberly J Ross, Susan M Rosenberg J Bacteriol 2006 new
Molecular analysis of ANT1, TWINKLE and POLG in patients with multiple deletions or depletion of mitochondrial DNA by a dHPLC-based assay. Mourad Naïmi, Sylvie Bannwarth, Vincent Procaccio, Jean Pouget, Claude Desnuelle, Jean-François Pellissier, Agnes Rötig, Arnold Munnich, Patrick Calvas, Christian Richelme, Philippe Jonveaux, Giovanni Castelnovo, Mariella Simon, Melvin Simon, Michel Clanet, Douglas Wallace, Véronique Paquis-Flucklinger European journal of human genetics : EJHG 2006 pols set
The spectrum of clinical disease caused by the A467T and W748S POLG mutations: a study of 26 cases. Charalampos Tzoulis, Bernt A Engelsen, Wenche Telstad, Jan Aasly, Massimo Zeviani, Synnøve Winterthun, Gianfrancesco Ferrari, Jan H Aarseth, Laurence A Bindoff Brain : a journal of neurology 2006 pols set
Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest. Xiaohui Bi, Laura R Barkley, Damien M Slater, Satoshi Tateishi, Masaru Yamaizumi, Haruo Ohmori, Cyrus Vaziri Molecular and cellular biology 2006 new
A new photoactive building block for investigation of DNA backbone interactions: photoaffinity labeling of human DNA polymerase beta. Meike Liebmann, Francesca Di Pasquale, Andreas Marx Chembiochem 2006 pols set
DNA polymerase catalysis in the absence of Watson-Crick hydrogen bonds: analysis by single-turnover kinetics. Olga Potapova, Chikio Chan, Angela M DeLucia, Sandra A Helquist, Eric T Kool, Nigel D F Grindley, Catherine M Joyce Biochemistry 2006 new
POLG1 in idiopathic Parkinson disease. Watcharee Tiangyou, Gavin Hudson, D Ghezzi, Gianfrancesco Ferrari, Massimo Zeviani, David J Burn, Patrick F Chinnery Neurology 2006 pols set
Fatal neonatal-onset mitochondrial respiratory chain disease with T cell immunodeficiency. Janine Reichenbach, Ralf Schubert, Rita Horvàth, Jens Petersen, Nancy Fütterer, Elisabeth Malle, Andreas Stumpf, Boris R Gebhardt, Ulrike Koehl, Burkhart Schraven, Stefan Zielen Pediatric research 2006 pols set
Dominant inheritance of premature ovarian failure associated with mutant mitochondrial DNA polymerase gamma. Alistair T Pagnamenta, Jan-Willem Taanman, Callum J Wilson, Neil E Anderson, Rosetta Marotta, Andrew J Duncan, Maria Bitner-Glindzicz, Robert W Taylor, Adrienne Laskowski, David R Thorburn, Shamima Rahman Human reproduction (Oxford, England) 2006 pols set
Dynamics of nucleotide incorporation: snapshots revealed by 2-aminopurine fluorescence studies. Chithra Hariharan, Linda B Bloom, Sandra A Helquist, Eric T Kool, Linda J Reha-Krantz Biochemistry 2006 partial results
Translesion synthesis past the C8- and N2-deoxyguanosine adducts of the dietary mutagen 2-Amino-3-methylimidazo[4,5-f]quinoline in the NarI recognition sequence by prokaryotic DNA polymerases. James S Stover, Goutam Chowdhury, Hong Zang, F Peter Guengerich, Carmelo J Rizzo Chemical research in toxicology 2006 topics set
Translesion synthesis across polycyclic aromatic hydrocarbon diol epoxide adducts of deoxyadenosine by Sulfolobus solfataricus DNA polymerase Dpo4. Hong Zang, Goutam Chowdhury, Karen C Angel, Thomas M Harris, F Peter Guengerich Chemical research in toxicology 2006 topics set
Site-directed mutational analysis of structural interactions of low molecule compounds binding to the N-terminal 8 kDa domain of DNA polymerase beta. Shizuka Murakami, Shinji Kamisuki, Kei-ichi Takata, Nobuyuki Kasai, Seisuke Kimura, Yoshiyuki Mizushina, Keisuke Ohta, Fumio Sugawara, Kengo Sakaguchi Biochem Biophys Res Commun 2006 new
Thermal stability landscape for Klenow DNA polymerase as a function of pH and salt concentration. Allison J Richard, Chin-Chi Liu, Alexandra L Klinger, Matthew J Todd, Tara M Mezzasalma, Vince J LiCata Biochimica et biophysica acta 2006 new
Rational attempts to optimize non-natural nucleotides for selective incorporation opposite an abasic site. Xuemei Zhang, Alison Donnelly, Irene Lee, Anthony J Berdis Biochemistry 2006 topics set
Modulation of the W748S mutation in DNA polymerase gamma by the E1143G polymorphismin mitochondrial disorders. Sherine S L Chan, Matthew J Longley, William C Copeland Hum Mol Genet 2006 pols set
Bioactive isomalabaricane triterpenoids from Rhabdastrella globostellata that stabilize the binding of DNA polymerase beta to DNA. Jason A Clement, Mei Li, Sidney M Hecht, David G I Kingston J Nat Prod 2006 new
Structure of the Escherichia coli DNA polymerase III epsilon-HOT proofreading complex. Thomas W Kirby, Scott Harvey, Eugene F DeRose, Sergey Chalov, Anna K Chikova, Fred W Perrino, Roel M Schaaper, Robert E London, Lars C Pedersen The Journal of biological chemistry 2006 topics set
Escherichia coli DNA polymerase II can efficiently bypass 3,N(4)-ethenocytosine lesions in vitro and in vivo. Abu Amar M Al Mamun, M Zafri Humayun Mutation research 2006 pols set
A broadly applicable method to characterize large DNA viruses and adenoviruses based on the DNA polymerase gene. Larry A Hanson, Mary R Rudis, Marcia Vasquez-Lee, Roy D Montgomery Virol J 2006 new
The role of DNA polymerase iota in UV mutational spectra. Jun-Hyuk Choi, Ahmad Besaratinia, Dong-Hyun Lee, Chong-Soon Lee, Gerd P Pfeifer Mutation research 2006 new
Beta-sitosterol-3-O-beta-D-glucopyranoside: a eukaryotic DNA polymerase lambda inhibitor. Yoshiyuki Mizushina, Rumi Nakanishi, Isoko Kuriyama, Kohei Kamiya, Toshiko Satake, Noriko Shimazaki, Osamu Koiwai, Yukinobu Uchiyama, Yuko Yonezawa, Masaharu Takemura, Kengo Sakaguchi, Hiromi Yoshida J Steroid Biochem Mol Biol 2006 pols set
Simulating the effect of DNA polymerase mutations on transition-state energetics and fidelity: evaluating amino acid group contribution and allosteric coupling for ionized residues in human pol beta. Yun Xiang, Peter Oelschlaeger, Jan Florián, Myron F Goodman, Arieh Warshel Biochemistry 2006 new
Role of Pseudomonas aeruginosa dinB-encoded DNA polymerase IV in mutagenesis. Laurie H Sanders, Andrea Rockel, Haiping Lu, Daniel J Wozniak, Mark D Sutton J Bacteriol 2006 pols set
Over-expression and characterization of the recombinant small heat shock protein from Pyrococcus furiosus. Huayou Chen, Zhongmei Chu, Yongqing Zhang, Shengli Yang Biotechnology letters 2006 pols set
Analysis of equid herpesvirus 1 strain variation reveals a point mutation of the DNA polymerase strongly associated with neuropathogenic versus nonneuropathogenic disease outbreaks. J Nugent, I Birch-Machin, K C Smith, J A Mumford, Z Swann, J R Newton, R J Bowden, G P Allen, N Davis-Poynter J Virol 2006 new
DNA polymerase zeta accounts for the reduced cytotoxicity and enhanced mutagenicity of cisplatin in human colon carcinoma cells that have lost DNA mismatch repair. Xinjian Lin, Julie Trang, Tsuyoshi Okuda, Stephen B Howell Clin Cancer Res 2006 new
DNA polymerase gamma in mitochondrial DNA replication and repair. Maria A Graziewicz, Matthew J Longley, William C Copeland Chem Rev 2006 new
Monoubiquitination of proliferating cell nuclear antigen induced by stalled replication requires uncoupling of DNA polymerase and mini-chromosome maintenance helicase activities. Debbie J Chang, Patrick J Lupardus, Karlene A Cimprich The Journal of biological chemistry 2006 new
5-(Hydroxymethyl)-2-furfural: a selective inhibitor of DNA polymerase lambda and terminal deoxynucleotidyltransferase. Yoshiyuki Mizushina, Etsuko Yagita, Kouji Kuramochi, Isoko Kuriyama, Noriko Shimazaki, Osamu Koiwai, Yukinobu Uchiyama, Yuko Yomezawa, Fumio Sugawara, Susumu Kobayashi, Kengo Sakaguchi, Hiromi Yoshida Arch Biochem Biophys 2006 pols set
TSAO derivatives, inhibitors of HIV-1 reverse transcriptase dimerization: recent progress. María-José Camarasa, Sonsoles Velázquez, Ana San-Félix, María-Jesús Pérez-Pérez, María-Cruz Bonache, Sonia de Castro Current pharmaceutical design 2006 pols set
The DNA polymerase lambda is required for the repair of non-compatible DNA double strand breaks by NHEJ in mammalian cells. Jean-Pascal Capp, François Boudsocq, Pascale Bertrand, Audrey Laroche-Clary, Philippe Pourquier, Bernard S Lopez, Christophe Cazaux, Jean-Sébastien Hoffmann, Yvan Canitrot Nucleic acids research 2006 new
Direct interaction of p21 with p50, the small subunit of human DNA polymerase delta. Hao Li, Bin Xie, Amal A Rahmeh, Yanjiao Zhou, Marietta Y W T Lee Cell Cycle 2006 pols set
Visualization of the interaction between archaeal DNA polymerase and uracil-containing DNA by atomic force microscopy. Yasuo Asami, Masahiro Murakami, Masatomi Shimizu, Francesca M Pisani, Isamu Hayata, Takehiko Nohmi Genes Cells 2006 new
Coexpression of the subunits of T7 DNA polymerase from an artificial operon allows one-step purification of active gp5/Trx complex. Joyce Chiu, Daniel Tillett, Paul E March Protein Expr Purif 2006 pols set
Hybrid antibacterials. DNA polymerase-topoisomerase inhibitors. Chengxin Zhi, Zheng-Yu Long, Andrzej Manikowski, Jeanne Comstock, Wei-Chu Xu, Neal C Brown, Paul M Tarantino, Karsten A Holm, Edward J Dix, George E Wright, Marjorie H Barnes, Michelle M Butler, Kimberly A Foster, William A LaMarr, Benoit Bachand, Richard Bethell, Caroline Cadilhac, Sylvie Charron, Serge Lamothe, Irina Motorina, Richard Storer J Med Chem 2006 new
Inhibitory effect of coenzyme Q on eukaryotic DNA polymerase gamma and DNA topoisomerase II activities on the growth of a human cancer cell line. Yuko Yonezawa, Isoko Kuriyama, Atsushi Fukuoh, Tsuyoshi Muta, Dongchon Kang, Masaharu Takemura, Ikunoshin Kato, Hiromi Yoshida, Yoshiyuki Mizushina Cancer Sci 2006 pols set
Plasticity of the gene functions for DNA replication in the T4-like phages. Vasiliy M Petrov, James M Nolan, Claire Bertrand, Dawn Levy, Carine Desplats, H M Krisch, Jim D Karam Journal of molecular biology 2006 topics set
Mutant POLG2 disrupts DNA polymerase gamma subunits and causes progressive external ophthalmoplegia. Matthew J Longley, Susanna Clark, Cynthia Yu Wai Man, Gavin Hudson, Steve E Durham, Robert W Taylor, Simon Nightingale, Douglass M Turnbull, William C Copeland, Patrick F Chinnery Am J Hum Genet 2006 new
Remarkable sensitivity to DNA base shape in the DNA polymerase active site. Herman O Sintim, Eric T Kool Angew Chem Int Ed Engl 2006 new
A human DNA polymerase eta complex containing Rad18, Rad6 and Rev1; proteomic analysis and targeting of the complex to the chromatin-bound fraction of cells undergoing replication fork arrest. Mayumi S Yuasa, Chikahide Masutani, Akihiko Hirano, Martin A Cohn, Masaru Yamaizumi, Yoshihiro Nakatani, Fumio Hanaoka Genes Cells 2006 pols set
Quantitative molecular diagnosis of axillary drainage fluid for prediction of locoregional failure in patients with one to three positive axillary nodes after mastectomy without adjuvant radiotherapy. Yongqing Zhang, Qing Yong Ma, Cheng Xue Dang, M Moureau-Zabotto, Wu Ke Chen International journal of radiation oncology, biology, physics 2006 new
Effects of drug resistance on viral load in patients failing antiretroviral therapy. N Machouf, R Thomas, V K Nguyen, B Trottier, M R Boulassel, Mark A. Wainberg, Jean-Pierre Routy Journal of medical virology 2006 pols set
The C-terminal residues of bacteriophage T7 gene 4 helicase-primase coordinate helicase and DNA polymerase activities. Seung-Joo Lee, Boriana Marintcheva, Samir M Hamdan, Charles C Richardson The Journal of biological chemistry 2006 pols set
Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion. Olga Rechkoblit, Lucy Malinina, Yuan Cheng, Vitaly Kuryavyi, Suse Broyde, Nicholas E Geacintov, Dinshaw J Patel PLoS Biol 2006 topics set
Preliminary characterization of a thermostable DNA polymerase I from a mesophilic Bacillus sphaericus strain C3-41. Han Bei, Liu Haizhou, Hu Xiaomin, Yuan Zhiming Arch Microbiol 2006 new
Functional human mitochondrial DNA polymerase gamma forms a heterotrimer. Elena Yakubovskaya, Zhixin Chen, José A Carrodeguas, Caroline Kisker, Daniel F Bogenhagen The Journal of biological chemistry 2006 new
Double-stranded DNA binding, an unusual property of DNA polymerase epsilon, promotes epigenetic silencing in Saccharomyces cerevisiae. Toshiaki Tsubota, Rie Tajima, Kunitomo Ode, Hajime Kubota, Naoshi Fukuhara, Takeshi Kawabata, Satoko Maki, Hisaji Maki The Journal of biological chemistry 2006 pols set
Role of DNA polymerase theta in tolerance of endogenous and exogenous DNA damage in mouse B cells. Akiko Ukai, Takako Maruyama, Shigenobu Mochizuki, Rika Ouchida, Keiji Masuda, Kiyoko Kawamura, Masatoshi Tagawa, Kazuo Kinoshita, Akemi Sakamoto, Takeshi Tokuhisa, Jiyang O-Wang Genes Cells 2006 new
Human DNA polymerase N (POLN) is a low fidelity enzyme capable of error-free bypass of 5S-thymine glycol. Kei-ichi Takata, Tatsuhiko Shimizu, Shigenori Iwai, Richard D Wood The Journal of biological chemistry 2006 partial results
Correct and incorrect nucleotide incorporation pathways in DNA polymerase beta. Ravi Radhakrishnan, Tamar Schlick Biochem Biophys Res Commun 2006 topics set
Structure of purine-purine mispairs during misincorporation and extension by Escherichia coli DNA polymerase I. Angie M Kretulskie, Thomas E Spratt Biochemistry 2006 pols set
Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): modeling and dynamics studies. Ling Zhang, Olga Rechkoblit, Liming Wang, Dinshaw J Patel, Robert Shapiro, Suse Broyde Nucleic acids research 2006 topics set
HIV-1 RNase H: recent progress in an exciting, yet little explored, drug target. Enzo Tramontano Mini Rev Med Chem 2006 new
Essential residues in the C terminus of the bacteriophage T7 gene 2.5 single-stranded DNA-binding protein. Boriana Marintcheva, Samir M Hamdan, Seung-Joo Lee, Charles C Richardson The Journal of biological chemistry 2006 pols set
A novel function of DNA polymerase zeta regulated by PCNA. Matthew R Northam, Parie Garg, Dmitri M Baitin, Peter M J Burgers, Polina V Shcherbakova The EMBO journal 2006 new
Characterization and application of aptamers for Taq DNA polymerase selected using an evolution-mimicking algorithm. Takahisa Noma, Koji Sode, Kazunori Ikebukuro Biotechnol Lett 2006 pols set
GINS is a DNA polymerase epsilon accessory factor during chromosomal DNA replication in budding yeast. Takashi Seki, Masaki Akita, Yoichiro Kamimura, Sachiko Muramatsu, Hiroyuki Araki, Akio Sugino The Journal of biological chemistry 2006 new
Crystal structure of the cytomegalovirus DNA polymerase subunit UL44 in complex with the C terminus from the catalytic subunit. Differences in structure and function relative to unliganded UL44. Brent A Appleton, Justin Brooks, Arianna Loregian, David J Filman, Donald M Coen, James M Hogle The Journal of biological chemistry 2006 topics set
Structure and enzymatic properties of a chimeric bacteriophage RB69 DNA polymerase and single-stranded DNA binding protein with increased processivity. Siyang Sun, Linda Geng, Yousif Shamoo Proteins 2006 partial results
DNA detection using recombination proteins. Olaf Piepenburg, Colin H Williams, Derek L Stemple, Niall A Armes PLoS Biol 2006 pols set
Sequential side-chain residue motions transform the binary into the ternary state of DNA polymerase lambda. Meredith C Foley, Karunesh Arora, Tamar Schlick Biophys J 2006 new
Single-molecule investigation of the T4 bacteriophage DNA polymerase holoenzyme: multiple pathways of holoenzyme formation. R Derike Smiley, Zhihao Zhuang, Stephen J Benkovic, Gordon G Hammes Biochemistry 2006 topics set
Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase. Miguel Garcia-Diaz, Katarzyna Bebenek, Joseph M Krahn, Lars C Pedersen, Thomas A Kunkel Cell 2006 topics set
Fission yeast Mcm10p contains primase activity. Karen Fien, Jerard Hurwitz The Journal of biological chemistry 2006 new
Promiscuous mismatch extension by human DNA polymerase lambda. Angel J Picher, Miguel García-Díaz, Katarzyna Bebenek, Lars C Pedersen, Thomas A Kunkel, Luis Blanco Nucleic acids research 2006 topics set
DNA primase acts as a molecular brake in DNA replication. Jong-Bong Lee, Richard K Hite, Samir M Hamdan, X Sunney Xie, Charles C Richardson, Antoine M van Oijen Nature 2006 new
A conserved Hsp10-like domain in Mcm10 is required to stabilize the catalytic subunit of DNA polymerase-alpha in budding yeast. Robin M Ricke, Anja-Katrin Bielinsky The Journal of biological chemistry 2006 new
Mgs1 and Rad18/Rad5/Mms2 are required for survival of Saccharomyces cerevisiae mutants with novel temperature/cold sensitive alleles of the DNA polymerase delta subunit, Pol31. Niloofar Davoodi Vijeh Motlagh, Masayuki Seki, Dana Branzei, Takemi Enomoto DNA repair 2006 pols set
Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus. Sherwin P Montaño, Marie L Coté, Monica J Roth, Millie M Georgiadis Nucleic acids research 2006 topics set
Human cytomegalovirus DNA polymerase catalytic subunit pUL54 possesses independently acting nuclear localization and ppUL44 binding motifs. Gualtiero Alvisi, Alessandro Ripalti, Apollinaire Ngankeu, Maila Giannandrea, Stefano G Caraffi, Manisha M Dias, David A Jans Traffic 2006 pols set
Deficiency of the Caenorhabditis elegans DNA polymerase eta homologue increases sensitivity to UV radiation during germ-line development. Tsuyoshi Ohkumo, Chikahide Masutani, Toshihiko Eki, Fumio Hanaoka Cell Struct Funct 2006 new
Inhibitory effect of tocotrienol on eukaryotic DNA polymerase lambda and angiogenesis. Yoshiyuki Mizushina, Kiyotaka Nakagawa, Akira Shibata, Yasutoshi Awata, Isoko Kuriyama, Noriko Shimazaki, Osamu Koiwai, Yukinobu Uchiyama, Kengo Sakaguchi, Teruo Miyazawa, Hiromi Yoshida Biochem Biophys Res Commun 2006 pols set
Kinetic evidence for inefficient and error-prone bypass across bulky N2-guanine DNA adducts by human DNA polymerase iota. Jeong-Yun Choi, F Peter Guengerich The Journal of biological chemistry 2006 pols set
Comprehensive search for DNA polymerase in the hyperthermophilic archaeon, Pyrococcus furiosus. Sonoko Ishino, Yoshizumi Ishino Nucleosides, nucleotides & nucleic acids 2006 new
Subtle but variable conformational rearrangements in the replication cycle of Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4) may accommodate lesion bypass. Yazhen Wang, Karunesh Arora, Tamar Schlick Protein science : a publication of the Protein Society 2006 topics set
Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer. Chad A Dumstorf, Alan B Clark, Qingcong Lin, Grace E Kissling, Tao Yuan, Raju Kucherlapati, William Glenn McGregor, Thomas A Kunkel Proceedings of the National Academy of Sciences of the United States of America 2006 new
Synthesis, DNA polymerase incorporation, and enzymatic phosphate hydrolysis of formamidopyrimidine nucleoside triphosphates. Shuhei Imoto, Jennifer N Patro, Yu Lin Jiang, Natsuhisa Oka, Marc M Greenberg Journal of the American Chemical Society 2006 pols set
RecA acts in trans to allow replication of damaged DNA by DNA polymerase V. Katharina Schlacher, Michael M Cox, Roger Woodgate, Myron F Goodman Nature 2006 new
Stoichiometric complex formation by proliferating cell nuclear antigen (PCNA) and its interacting protein: purification and crystallization of the DNA polymerase and PCNA monomer mutant complex from Pyrococcus furiosus. Hirokazu Nishida, Shigeki Matsumiya, Daisuke Tsuchiya, Yoshizumi Ishino, Kosuke Morikawa Acta Crystallogr Sect F Struct Biol Cryst Commun 2006 pols set
Mitochondrial genome of the moon jelly Aurelia aurita (Cnidaria, Scyphozoa): A linear DNA molecule encoding a putative DNA-dependent DNA polymerase. Zhiyong Shao, Shannon Graf, Oleg Y Chaga, Dennis V Lavrov Gene 2006 new
A mass spectrometry-based approach for identifying novel DNA polymerase substrates from a pool of dNTP analogues. Kristi Kincaid, Robert D Kuchta Nucleic acids research 2006 new
Role of helix P of the human cytomegalovirus DNA polymerase in resistance and hypersusceptibility to the antiviral drug foscarnet. Egor P Tchesnokov, Christian Gilbert, Guy Boivin, Matthias Götte J Virol 2006 pols set
Telomere repeat binding factor 2 interacts with base excision repair proteins and stimulates DNA synthesis by DNA polymerase beta. Meltem Muftuoglu, Heng Kuan Wong, Syed Z Imam, David M Wilson, Vilhelm A Bohr, Patricia L Opresko Cancer research 2006 new
ATR homolog Mec1 controls association of DNA polymerase zeta-Rev1 complex with regions near a double-strand break. Yukinori Hirano, Katsunori Sugimoto Current biology : CB 2006 new
Comparative analysis of eubacterial DNA polymerase III alpha subunits. Xiao-Qian Zhao, Jian-Fei Hu, Jun Yu Genomics Proteomics Bioinformatics 2006 new
Crystal structure of a DNA polymerase sliding clamp from a Gram-positive bacterium. Maria A Argiriadi, Eric R Goedken, Irina Bruck, Mike E O'Donnell, John Kuriyan BMC Struct Biol 2006 new
Protein trans-splicing and characterization of a split family B-type DNA polymerase from the hyperthermophilic archaeal parasite Nanoarchaeum equitans. Jeong Jin Choi, Ki Hoon Nam, Bokkee Min, Soon-Jong Kim, Dieter Söll, Suk-Tae Kwon Journal of molecular biology 2006 new
Stabilization of Taq DNA polymerase at high temperature by protein folding pathways from a hyperthermophilic archaeon, Pyrococcus furiosus. Pongpan Laksanalamai, Andrey R Pavlov, Alexei I Slesarev, Frank T Robb Biotechnol Bioeng 2006 pols set
[Vector-mediated RNA interference of DNA polymerase beta in human bronchial epithelial cells]. Da-Lin Hu, Zhi-Xiong Zhuang, Yi-min Liu, Yun He Wei Sheng Yan Jiu 2006 new
Therapeutic strategies towards HIV-1 infection in macrophages. CF Perno, Valentina Svicher, Dominique Schols, Michela Pollicita, Jan Balzarini, Stefano Aquaro Antiviral research 2006 pols set
Translesion synthesis across O6-alkylguanine DNA adducts by recombinant human DNA polymerases. Jeong-Yun Choi, Goutam Chowdhury, Hong Zang, Karen C Angel, Choua C Vu, Lisa A Peterson, F Peter Guengerich The Journal of biological chemistry 2006 pols set
HIV-1 reverse transcriptase structure with RNase H inhibitor dihydroxy benzoyl naphthyl hydrazone bound at a novel site. Daniel M Himmel, Stefan G Sarafianos, Sanjeewa Dharmasena, Mohammed M Hossain, Kessler McCoy-Simandle, Tatiana Ilina, Arthur D Clark, Jennifer L Knight, John G Julias, Patrick K Clark, Karsten Krogh-Jespersen, Ronald M Levy, Stephen H Hughes, Michael A. Parniak, Edward Arnold ACS Chem Biol 2006 partial results
An intrinsic 5'-deoxyribose-5-phosphate lyase activity in DNA polymerase beta from Leishmania infantum supports a role in DNA repair. Ana Alonso, Gloria Terrados, Angel J Picher, Rafael Giraldo, Luis Blanco, Vicente Larraga DNA repair 2006 new
Combining mutations in HIV-1 reverse transcriptase with mutations in the HIV-1 polypurine tract affects RNase H cleavages involved in PPT utilization. Mary Jane McWilliams, John G Julias, Stefan G Sarafianos, W Gregory Alvord, Edward Arnold, Stephen H Hughes Virology 2006 pols set
Origins of human mitochondrial point mutations as DNA polymerase gamma-mediated errors. Weiming Zheng, Konstantin Khrapko, Hilary A Coller, William G Thilly, William C Copeland Mutation research 2006 new
Calcium is a cofactor of polymerization but inhibits pyrophosphorolysis by the Sulfolobus solfataricus DNA polymerase Dpo4. Adriana Irimia, Hong Zang, Lioudmila V Loukachevitch, Robert Lawton Eoff, F Peter Guengerich, Martin Egli Biochemistry 2006 topics set
DNA polymerase 4 of Saccharomyces cerevisiae is important for accurate repair of methyl-methanesulfonate-induced DNA damage. Catherine H Sterling, Joann B Sweasy Genetics 2006 new
Inhibition of human telomerase reverse transcriptase by nonsteroidal antiinflammatory drugs in colon carcinoma. Hua He, Harry Hua-Xiang Xia, Ji De Wang, Qing Gu, Marie Chia-Mi Lin, Bing Zou, Shiu Kum Lam, Annie O O Chan, Man Fung Yuen, Hsiang Fu Kung, Benjamin Chun-Yu Wong Cancer 2006 new
[Security of dual cancer-specific targeting vector and its cytotoxic effect when harbored]. Juan Wang, Jin-Fa Gu, Shui-Yun Yang, Tian Xiao, Rong Qi, Lan-Ying Sun, Xin-Yuan Liu Ai zheng = Aizheng = Chinese journal of cancer 2006 new
Regulation of DNA repair fidelity by molecular checkpoints: "gates" in DNA polymerase beta's substrate selection. Ravi Radhakrishnan, Karunesh Arora, Yazhen Wang, William A Beard, Samuel H Wilson, Tamar Schlick Biochemistry 2006 new
Short-term antiviral activity of TMC278--a novel NNRTI--in treatment-naive HIV-1-infected subjects. Frank Goebel, Alexy Yakovlev, Anton L Pozniak, Elena Vinogradova, Griet Boogaerts, Richard Hoetelmans, Marie-Pierre P De Béthune, Monika Peeters, Brian Woodfall AIDS 2006 new
Localization of Y-family polymerases and the DNA polymerase switch in mammalian cells. Patricia L Kannouche, Alan R Lehmann Methods in enzymology 2006 new
p53 deficiency rescues apoptosis and differentiation of multiple cell types in zebrafish flathead mutants deficient for zygotic DNA polymerase delta1. N Plaster, C Sonntag, C E Busse, M Hammerschmidt Cell Death Differ 2006 new
Hypoxia-inducible factor-1 mediates the expression of DNA polymerase iota in human tumor cells. Akiko Ito, Nobuko Koshikawa, Shigenobu Mochizuki, Ken Omura, Keizo Takenaga Biochem Biophys Res Commun 2006 new
DNA polymerase X from African swine fever virus: quantitative analysis of the enzyme-ssDNA interactions and the functional structure of the complex. Maria J Jezewska, Agnieszka Marcinowicz, Aaron L Lucius, Wlodzimierz Bujalowski Journal of molecular biology 2006 new
Activities and mechanism of DNA polymerase beta. William A Beard, Rajendra Prasad, Samuel H Wilson Methods in enzymology 2006 new
DNA polymerase programmed with a hairpin DNA incorporates a multiple-instruction architecture into molecular computing. Ken Komiya, Kensaku Sakamoto, Atsushi Kameda, Masahito Yamamoto, Azuma Ohuchi, Daisuke Kiga, Shigeyuki Yokoyama, Masami Hagiya Biosystems 2006 new
Structural relationship of curcumin derivatives binding to the BRCT domain of human DNA polymerase lambda. Toshifumi Takeuchi, Tomomi Ishidoh, Hiroshi Iijima, Isoko Kuriyama, Noriko Shimazaki, Osamu Koiwai, Kouji Kuramochi, Susumu Kobayashi, Fumio Sugawara, Kengo Sakaguchi, Hiromi Yoshida, Yoshiyuki Mizushina Genes Cells 2006 pols set
Chaos and order in spontaneous mutation. John W Drake Genetics 2006 topics set
Characterization of the global transcriptional responses to different types of DNA damage and disruption of replication in Bacillus subtilis. Alexi I Goranov, Elke Kuester-Schoeck, Jue D Wang, Alan D Grossman Journal of bacteriology 2006 new
The L561A substitution in the nascent base-pair binding pocket of RB69 DNA polymerase reduces base discrimination. Haijiang Zhang, Chanu Rhee, Anna Bebenek, John W Drake, Jianhong Wang, William H Konigsberg Biochemistry 2006 complete
Difference in expression level and localization of DNA polymerase beta among human esophageal cancer focus, adjacent and corresponding normal tissues. Z M Dong, N G Zheng, J L Wu, S K Li, Y L Wang Dis Esophagus 2006 new
Haploinsufficiency in DNA polymerase beta increases cancer risk with age and alters mortality rate. Diane C Cabelof, Yuji Ikeno, Abraham Nyska, Rita A Busuttil, Njwen Anyangwe, Jan Vijg, Larry H Matherly, James D Tucker, Samuel H Wilson, Arlan Richardson, Ahmad R Heydari Cancer research 2006 new
Crystal structure of the herpes simplex virus 1 DNA polymerase. Shenping Liu, John D Knafels, Jeanne S Chang, Gregory A Waszak, Eric T Baldwin, Martin R Deibel, Darrell R Thomsen, Fred L Homa, Peter A Wells, Monica C Tory, Roger A Poorman, Hua Gao, Xiayang Qiu, Andrew P Seddon The Journal of biological chemistry 2006 topics set
Biochemical basis of genotoxicity of heterocyclic arylamine food mutagens: Human DNA polymerase eta selectively produces a two-base deletion in copying the N2-guanyl adduct of 2-amino-3-methylimidazo[4,5-f]quinoline but not the C8 adduct at the NarI G3 site. Jeong-Yun Choi, James S Stover, Karen C Angel, Goutam Chowdhury, Carmelo J Rizzo, F Peter Guengerich The Journal of biological chemistry 2006 pols set
Varying DNA base-pair size in subangstrom increments: evidence for a loose, not large, active site in low-fidelity Dpo4 polymerase. Shin Mizukami, Tae Woo Kim, Sandra A Helquist, Eric T Kool Biochemistry 2006 topics set
Roles of DNA polymerase V and RecA protein in SOS damage-induced mutation. Katharina Schlacher, Phuong Pham, Michael M Cox, Myron F Goodman Chem Rev 2006 new
RNA aptamers selected against DNA polymerase beta inhibit the polymerase activities of DNA polymerases beta and kappa. Leonid V Gening, Svetlana A Klincheva, Anastasia Reshetnjak, Arthur P Grollman, Holly Miller Nucleic acids research 2006 new
Site-directed mutations of T4 helicase loading protein (gp59) reveal multiple modes of DNA polymerase inhibition and the mechanism of unlocking by gp41 helicase. Scott W Nelson, Jingsong Yang, Stephen J Benkovic The Journal of biological chemistry 2006 new
Affinity capture of a mammalian DNA polymerase beta by inhibitors immobilized to resins used in solid-phase organic synthesis. Kouji Kuramochi, Tetsuya Haruyama, Ryo Takeuchi, Takashi Sunoki, Madoka Watanabe, Masahiko Oshige, Susumu Kobayashi, Kengo Sakaguchi, Fumio Sugawara Bioconjug Chem 2005 pols set
Sensitivity to phosphonoacetic acid: a new phenotype to probe DNA polymerase delta in Saccharomyces cerevisiae. Lin Li, Kelly M Murphy, Uliana Kanevets, Linda J Reha-Krantz Genetics 2005 complete Linda J Reha-Krantz*
[Inhibitory effect of hTERT dsRNA on telomerase activity in lung carcinoma cell line A549]. Feng-Jun Tian, Zhi-Yong Wang, Jun-Yi Ma, Yun-Xia Zhao, Wei Lu Ai zheng = Aizheng = Chinese journal of cancer 2005 new
Contribution of polar residues of the J-helix in the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I (Klenow fragment): Q677 regulates the removal of terminal mismatch. Kamalendra Singh, Mukund J Modak Biochemistry 2005 partial results
Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint. Tony S Byun, Marcin Pacek, Muh-ching Yee, Johannes C Walter, Karlene A Cimprich Genes Dev 2005 new
Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry. Heike Hofmann, Krzysztof Pyrc, Lia van der Hoek, Martina Geier, Ben Berkhout, Stefan Pöhlmann Proceedings of the National Academy of Sciences of the United States of America 2005 new
Comparison of single regulated lentiviral vectors with rtTA expression driven by an autoregulatory loop or a constitutive promoter. David Markusic, Ronald Oude-Elferink, Atze T Das, Ben Berkhout, Jurgen Seppen Nucleic acids research 2005 new
Biochemical properties of Saccharomyces cerevisiae DNA polymerase IV. Katarzyna Bebenek, Miguel Garcia-Diaz, Steven R Patishall, Thomas A Kunkel The Journal of biological chemistry 2005 pols set
Error-prone and inefficient replication across 8-hydroxyguanine (8-oxoguanine) in human and mouse ras gene fragments by DNA polymerase kappa. Paweł Jałoszyński, Eiji Ohashi, Haruo Ohmori, Susumu Nishimura Genes Cells 2005 new
Contribution of DNA polymerase eta to immunoglobulin gene hypermutation in the mouse. Frédéric Delbos, Annie De Smet, Ahmad Faili, Said Aoufouchi, Jean-Claude Weill, Claude-Agnès Reynaud J Exp Med 2005 new
Modulation of cellular response to cisplatin by a novel inhibitor of DNA polymerase beta. François Boudsocq, P Benaim, Yvan Canitrot, Martine Knibiehler, Frédéric Ausseil, Jean-Pascal Capp, Anne Bieth, Christophe Long, Bruno David, Igor V Shevelev, E Frierich-Heinecken, Ulrich Hübscher, F Amalric, Georges Massiot, Jean-Sébastien Hoffmann, Christophe Cazaux Mol Pharmacol 2005 new
The bacteriophage P1 hot gene product can substitute for the Escherichia coli DNA polymerase III {theta} subunit. Anna K Chikova, Roel M Schaaper J Bacteriol 2005 pols set
Systematic synthesis of galloyl-substituted procyanidin B1 and B2, and their ability of DPPH radical scavenging activity and inhibitory activity of DNA polymerases. Akiko Saito, Yoshiyuki Mizushina, Hiroshi Ikawa, Hiromi Yoshida, Yuki Doi, Akira Tanaka, Noriyuki Nakajima Bioorganic & medicinal chemistry 2005 new
Mismatch-induced conformational distortions in polymerase beta support an induced-fit mechanism for fidelity. Karunesh Arora, William A Beard, Samuel H Wilson, Tamar Schlick Biochemistry 2005 new
Usefulness of repeated GenomiPhi, a phi29 DNA polymerase-based rolling circle amplification kit, for generation of large amounts of plasmid DNA. Masahiro Sato, Masato Ohtsuka, Yuhsuke Ohmi Biomol Eng 2005 pols set
Human DNA polymerase iota promotes replication through a ring-closed minor-groove adduct that adopts a syn conformation in DNA. William T Wolfle, Robert E Johnson, Irina G Minko, R Stephen Lloyd, Satya Prakash, Louise Prakash Molecular and cellular biology 2005 pols set
Construction of a minimal HIV-1 variant that selectively replicates in leukemic derived T-cell lines: towards a new virotherapy approach. Rienk E Jeeninga, Barbara Jan, Birgit van der Linden, Henk van den Berg, Ben Berkhout Cancer research 2005 new
The pH-dependent mismatch formation by DNA polymerase eta. Shunji Izuta, Naomi Nishimoto Nucleic Acids Symp Ser (Oxf) 2005 new
Alternative tRNA priming of human immunodeficiency virus type 1 reverse transcription explains sequence variation in the primer-binding site that has been attributed to APOBEC3G activity. Atze T Das, Monique Vink, Ben Berkhout J Virol 2005 new
Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4+ T lymphocytes. Marloes A Naarding, Irene S Ludwig, Fedde Groot, Ben Berkhout, Teunis B H Geijtenbeek, Georgios Pollakis, William A Paxton J Clin Invest 2005 new
A closed conformation for the Pol lambda catalytic cycle. Miguel Garcia-Diaz, Katarzyna Bebenek, Joseph M Krahn, Thomas A Kunkel, Lars C Pedersen Nature structural & molecular biology 2005 topics set
A specific subdomain in phi29 DNA polymerase confers both processivity and strand-displacement capacity. Irene Rodríguez, José María Lázaro, Luis Blanco, Satwik Kamtekar, Andrea J Berman, Jianhong Wang, Thomas A Steitz, Margarita Salas, Miguel de Vega Proceedings of the National Academy of Sciences of the United States of America 2005 partial results
The discovery of RNA polymerase. Jerard Hurwitz The Journal of biological chemistry 2005 topics set
Base selectivity is impaired by mutants that perturb hydrogen bonding networks in the RB69 DNA polymerase active site. Guangwei Yang, Jianhong Wang, William H Konigsberg Biochemistry 2005 complete
Site-directed mutagenesis using Pfu DNA polymerase and T4 DNA ligase. Yair Adereth, Kristen J Champion, Tien Hsu, Vincent Dammai BioTechniques 2005 pols set
(+)-Myristinin A, a naturally occurring DNA polymerase beta inhibitor and potent DNA-damaging agent. David J Maloney, Jing-Zhen Deng, Shelley R Starck, Zhijie Gao, Sidney M Hecht Journal of the American Chemical Society 2005 new
A combination of decreased NRTI incorporation and decreased excision determines the resistance profile of HIV-1 K65R RT. Kirsten L White, Nicolas A Margot, John K Ly, James M Chen, Adrian S Ray, Martina Pavelko, Ruth Wang, Martin J McDermott, S Swaminathan, Michael D Miller Aids 2005 topics set
High-level overproduction of His-tagged Tth DNA polymerase in Thermus thermophilus. Renata Moreno, Amparo Haro, Angel Castellanos, José Berenguer Appl Environ Microbiol 2005 pols set
Design and synthesis of a 3'-O-allyl photocleavable fluorescent nucleotide as a reversible terminator for DNA sequencing by synthesis. Hameer Ruparel, Lanrong Bi, Zengmin Li, Xiaopeng Bai, Dae Hyun Kim, Nicholas J Turro, Jingyue Ju Proceedings of the National Academy of Sciences of the United States of America 2005 new
Roles of the Escherichia coli RecA protein and the global SOS response in effecting DNA polymerase selection in vivo. Robert W Maul, Mark D Sutton J Bacteriol 2005 new
Biochemical evidence for the requirement of Hoogsteen base pairing for replication by human DNA polymerase iota. Robert E Johnson, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2005 pols set
Suppression of RNA interference by adenovirus virus-associated RNA. M Gunnar Andersson, P C Joost Haasnoot, Ning Xu, Saideh Berenjian, Ben Berkhout, Göran Akusjärvi J Virol 2005 new
Sequence determination of nucleic acids containing 5-methylisocytosine and isoguanine: identification and insight into polymerase replication of the non-natural nucleobases. J David Ahle, Stephen Barr, A Michael Chin, Thomas R Battersby Nucleic acids research 2005 topics set
Herpes simplex virus type 1 DNA polymerase requires the mammalian chaperone hsp90 for proper localization to the nucleus. April D Burch, Sandra K Weller J Virol 2005 new
Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones. Scott R Budihas, Inna Gorshkova, Sergei A Gaidamakov, Antony Wamiru, Marion K Bona, Michael A. Parniak, Robert J Crouch, James B McMahon, John A Beutler, Stuart F J Le Grice Nucleic acids research 2005 new
A novel PDIP1-related protein, KCTD10, that interacts with proliferating cell nuclear antigen and DNA polymerase delta. Jianlin Zhou, Kaiqun Ren, Xin Liu, Xiwen Xiong, Xiaoxiao Hu, Jian Zhang Biochimica et biophysica acta 2005 new
A novel approach for inhibition of HIV-1 by RNA interference: counteracting viral escape with a second generation of siRNAs. Olivier Ter Brake, Ben Berkhout J RNAi Gene Silencing 2005 new
Human base excision repair enzymes apurinic/apyrimidinic endonuclease1 (APE1), DNA polymerase beta and poly(ADP-ribose) polymerase 1: interplay between strand-displacement DNA synthesis and proofreading exonuclease activity. Maria V Sukhanova, Svetlana N Khodyreva, Natalia A Lebedeva, Rajendra Prasad, Samuel H Wilson, Olga I Lavrik Nucleic acids research 2005 new
A thymine isostere in the templating position disrupts assembly of the closed DNA polymerase beta ternary complex. Thomas W Kirby, Eugene F DeRose, William A Beard, Samuel H Wilson, Robert E London Biochemistry 2005 new
Ubiquitinated proliferating cell nuclear antigen activates translesion DNA polymerases eta and REV1. Parie Garg, Peter M J Burgers Proceedings of the National Academy of Sciences of the United States of America 2005 new
Processivity factor of KSHV contains a nuclear localization signal and binding domains for transporting viral DNA polymerase into the nucleus. Yali Chen, Mihai Ciustea, Robert P Ricciardi Virology 2005 new
Efficient isothermal expansion of human telomeric and minisatellite repeats by Thermococcus litoralis DNA polymerase. Jörg S Hartig, Eric T Kool Nucleic acids research 2005 pols set
Biological characterization of novel inhibitors of the gram-positive DNA polymerase IIIC enzyme. Alexander Kuhl, Niels Svenstrup, Christoph Ladel, Michael Otteneder, Annegret Binas, Guido Schiffer, Michael Brands, Thomas Lampe, Karl Ziegelbauer, Helga Rübsamen-Waigmann, Dieter Haebich, Kerstin Ehlert Antimicrob Agents Chemother 2005 new
POLG mutations in Alpers syndrome. Khue V Nguyen, E Østergaard, S Holst Ravn, T Balslev, E Rubaek Danielsen, A Vardag, P J McKiernan, G Gray, Robert K Naviaux Neurology 2005 pols set
Genetic analysis of two Arabidopsis DNA polymerase epsilon subunits during early embryogenesis. Arnaud Ronceret, Jocelyne Guilleminot, Frédéric Lincker, Jose Gadea-Vacas, Valérie Delorme, Nicole Bechtold, Georges Pelletier, Michel Delseny, Marie-Edith Chabouté, Martine Devic Plant J 2005 new
Retroviral superinfection resistance. Micha Nethe, Ben Berkhout, Antoinette C van der Kuyl Retrovirology 2005 new
A host-guest approach for determining drug-DNA interactions: an example using netropsin. Kristie D Goodwin, Eric C Long, Millie M Georgiadis Nucleic acids research 2005 topics set
Surface-initiated growth of poly d(A-T) by Taq DNA polymerase. Young Shik Chi, Young Hwan Jung, Insung S Choi, Yang-Gyun Kim Langmuir 2005 pols set
Expression of DNA polymerase {beta} cancer-associated variants in mouse cells results in cellular transformation. Joann B Sweasy, Tieming Lang, Daniela Starcevic, Ka-Wai Sun, Char-Chang Lai, Daniel Dimaio, Shibani Dalal Proceedings of the National Academy of Sciences of the United States of America 2005 new
High mobility of flap endonuclease 1 and DNA polymerase eta associated with replication foci in mammalian S-phase nucleus. Lioudmila Solovjeva, Maria Svetlova, Lioudmila Sasina, Kyoji Tanaka, Masafumi Saijo, Igor Nazarov, Morton Bradbury, Nikolai Tomilin Mol Biol Cell 2005 new
Genetic and physical interactions between Schizosaccharomyces pombe Mcl1 and Rad2, Dna2 and DNA polymerase alpha: evidence for a multifunctional role of Mcl1 in DNA replication and repair. Yasuhiro Tsutsui, Takashi Morishita, Toyoaki Natsume, Kentaro Yamashita, Hiroshi Iwasaki, Fumiaki Yamao, Hideo Shinagawa Curr Genet 2005 new
Use of viscogens, dNTPalphaS, and rhodium(III) as probes in stopped-flow experiments to obtain new evidence for the mechanism of catalysis by DNA polymerase beta. Marina Bakhtina, Soojin Lee, Yu Wang, Chris Dunlap, Brandon J Lamarche, Ming-Daw Tsai Biochemistry 2005 new
POLG mutations and Alpers syndrome. Guido Davidzon, Michelangelo Mancuso, Silvio Ferraris, Catarina Quinzii, Michio Hirano, Heidi L Peters, Denise Kirby, David R Thorburn, Salvatore DiMauro Annals of neurology 2005 pols set
Phenotypic characterisation of cytomegalovirus DNA polymerase: a method to study cytomegalovirus isolates resistant to foscarnet. Alexandra Ducancelle, Jérôme Gravisse, Sophie Alain, Anne-Marie Fillet, Françoise Petit, Marie-José Sanson Le Pors, Marie-Christine Mazeron J Virol Methods 2005 new
Probing the active site tightness of DNA polymerase in subangstrom increments. Tae Woo Kim, James C Delaney, John M Essigmann, Eric T Kool Proceedings of the National Academy of Sciences of the United States of America 2005 new
The L74V mutation in human immunodeficiency virus type 1 reverse transcriptase counteracts enhanced excision of zidovudine monophosphate associated with thymidine analog resistance mutations. Luis R Miranda, Matthias Götte, Fei Liang, Daniel R Kuritzkes Antimicrob Agents Chemother 2005 topics set
Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN--gp120 interaction. Fedde Groot, Teunis B H Geijtenbeek, Rogier W Sanders, Christopher E Baldwin, Marta Sanchez-Hernandez, René Floris, Yvette van Kooyk, Esther C de Jong, Ben Berkhout J Virol 2005 new
Increased multinucleoside drug resistance and decreased replicative capacity of a human immunodeficiency virus type 1 variant with an 8-amino-Acid insert in the reverse transcriptase. Lia van der Hoek, Nicole Back, Maarten F Jebbink, Anthony de Ronde, Margreet Bakker, Suzanne Jurriaans, Peter Reiss, Neil Parkin, Ben Berkhout J Virol 2005 topics set
Aggressive HIV-1? Ben Berkhout, Anthony de Ronde, Lia van der Hoek Retrovirology 2005 new
Causal pathways of the effects of age and the CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on AIDS development. Ronald B Geskus, Laurence Meyer, Jean-Baptiste Hubert, Hanneke Schuitemaker, Ben Berkhout, Christine Rouzioux, Ioannis D Theodorou, Jean-François Delfraissy, Maria Prins, Roel A Coutinho J Acquir Immune Defic Syndr 2005 new
Synthesis and structural analysis of oxadiazole carboxamide deoxyribonucleoside analogs. Olga Adelfinskaya, Weidong Wu, V Jo Davisson, V J Davisson, Donald E Bergstrom Nucleosides, nucleotides & nucleic acids 2005 topics set
How the cell deals with DNA nicks. Parie Garg, Peter M J Burgers Cell Cycle 2005 new
Crystal structures for HIV-1 reverse transcriptase in complexes with three pyridinone derivatives: a new class of non-nucleoside inhibitors effective against a broad range of drug-resistant strains. Daniel M Himmel, Kalyan Das, Arthur D Clark, Stephen H Hughes, Abdellah Benjahad, Said Oumouch, Jérôme Guillemont, Sophie Coupa, Alain Poncelet, Imre Csoka, Christophe Meyer, Koen Andries, Chi Hung Nguyen, David S Grierson, Edward Arnold J Med Chem 2005 partial results
Pre-steady-state kinetic characterization of the DinB homologue DNA polymerase of Sulfolobus solfataricus. Janina Cramer, Tobias Restle The Journal of biological chemistry 2005 pols set
Mutations in the spacer region of Drosophila mitochondrial DNA polymerase affect DNA binding, processivity, and the balance between Pol and Exo function. Ningguang Luo, Laurie S Kaguni The Journal of biological chemistry 2005 new
Nuclear magnetic resonance solution structure of the Escherichia coli DNA polymerase III theta subunit. Geoffrey A Mueller, Thomas W Kirby, Eugene F DeRose, Dawei Li, Roel M Schaaper, Robert E London J Bacteriol 2005 topics set
Prostate-cancer-associated I260M variant of DNA polymerase beta is a sequence-specific mutator. Shibani Dalal, Suzanne E Hile, Kristin A Eckert, Ka-Wai Sun, Daniela Starcevic, Joann B Sweasy Biochemistry 2005 new
Using 2-aminopurine fluorescence to detect bacteriophage T4 DNA polymerase-DNA complexes that are important for primer extension and proofreading reactions. Chithra Hariharan, Linda J Reha-Krantz Biochemistry 2005 complete
Human DNA polymerase iota incorporates dCTP opposite template G via a G.C + Hoogsteen base pair. Deepak T Nair, Robert E Johnson, Louise Prakash, Satya Prakash, Aneel K Aggarwal Structure (London, England : 1993) 2005 topics set
Fidelity of mispair formation and mispair extension is dependent on the interaction between the minor groove of the primer terminus and Arg668 of DNA polymerase I of Escherichia coli. Melodie D McCain, Aviva S Meyer, Sherri S Schultz, Athanasios Glekas, Thomas E Spratt Biochemistry 2005 pols set
Tumor suppressor APC blocks DNA polymerase beta-dependent strand displacement synthesis during long patch but not short patch base excision repair and increases sensitivity to methylmethane sulfonate. Satya Narayan, Aruna S Jaiswal, Ramesh Balusu The Journal of biological chemistry 2005 new
Exploration of factors driving incorporation of unnatural dNTPS into DNA by Klenow fragment (DNA polymerase I) and DNA polymerase alpha. Kristi Kincaid, Jeff W Beckman, Aleksandra Zivkovic, Randall L Halcomb, Joachim W Engels, Robert D Kuchta Nucleic acids research 2005 pols set
Structure of the functional domain of phi29 replication organizer: insights into oligomerization and dna binding. Juan Luis Asensio, Armando Albert, Daniel Muñoz-Espín, Carlos Gonzalez, Juan Hermoso, Laurentino Villar, Jesús Jiménez-Barbero, Margarita Salas, Wilfried J J Meijer The Journal of biological chemistry 2005 pols set
Adduct size limits efficient and error-free bypass across bulky N2-guanine DNA lesions by human DNA polymerase eta. Jeong-Yun Choi, F Peter Guengerich Journal of molecular biology 2005 pols set
Inhibitory effect of conjugated eicosapentaenoic acid on mammalian DNA polymerase and topoisomerase activities and human cancer cell proliferation. Yuko Yonezawa, Takahiko Hada, Keisuke Uryu, Tsuyoshi Tsuzuki, Takahiro Eitsuka, Teruo Miyazawa, Chikako Murakami-Nakai, Hiromi Yoshida, Yoshiyuki Mizushina Biochem Pharmacol 2005 pols set
Distinct mechanisms of cis-syn thymine dimer bypass by Dpo4 and DNA polymerase eta. Robert E Johnson, Louise Prakash, Satya Prakash Proceedings of the National Academy of Sciences of the United States of America 2005 topics set
Improving the safety of a conditional-live human immunodeficiency virus type 1 vaccine by controlling both gene expression and cell entry. Atze T Das, Chris E Baldwin, Monique Vink, Ben Berkhout J Virol 2005 new
Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta. Toshiki Tsurimoto, Ayako Shinozaki, Masaki Yano, Masayuki Seki, Takemi Enomoto Genes Cells 2005 pols set
A lysine residue in the fingers subdomain of T7 DNA polymerase modulates the miscoding potential of 8-oxo-7,8-dihydroguanosine. Luis G Brieba, Robert J Kokoska, Katarzyna Bebenek, Thomas A Kunkel, Tom Ellenberger Structure (London, England : 1993) 2005 topics set
A homogeneous, high-throughput fluorescence resonance energy transfer-based DNA polymerase assay. Adam Shapiro, Olga Rivin, Ning Gao, Laurel Hajec Anal Biochem 2005 new
Addendum: Site-directed mutagenesis using Pfu DNA polymerase and T4 DNA ligase. BioTechniques 2005 pols set
Error-prone translesion synthesis by human DNA polymerase eta on DNA-containing deoxyadenosine adducts of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene. Dominic Chiapperino, Mangmang Cai, Jane M Sayer, Haruhiko Yagi, Heiko Kroth, Chikahide Masutani, Fumio Hanaoka, Donald M Jerina, Albert M Cheh The Journal of biological chemistry 2005 pols set
Fidelity discrimination in DNA polymerase beta: differing closing profiles for a mismatched (G:A) versus matched (G:C) base pair. Ravi Radhakrishnan, Tamar Schlick Journal of the American Chemical Society 2005 new
XRCC1 and DNA polymerase beta interaction contributes to cellular alkylating-agent resistance and single-strand break repair. Heng-Kuan Wong, David M Wilson J Cell Biochem 2005 new
MSH2-MSH6 stimulates DNA polymerase eta, suggesting a role for A:T mutations in antibody genes. Teresa M Wilson, Alexandra Vaisman, Stella A Martomo, Patsa Sullivan, Li Lan, Fumio Hanaoka, Akira Yasui, Roger Woodgate, Patricia J Gearhart J Exp Med 2005 new
Synthesis of novel poly(dG)-poly(dG)-poly(dC) triplex structure by Klenow exo- fragment of DNA polymerase I. Alexander B Kotlyar, Natalia Borovok, Tatiana Molotsky, Dmitry Klinov, Benjamin Dwir, Eli Kapon Nucleic acids research 2005 partial results
Mapping the interaction of DNA with the Escherichia coli DNA polymerase clamp loader complex. Eric R Goedken, Steven L Kazmirski, Gregory D Bowman, Mike E O'Donnell, John Kuriyan Nature structural & molecular biology 2005 pols set
DNA elongation by the human DNA polymerase lambda polymerase and terminal transferase activities are differentially coordinated by proliferating cell nuclear antigen and replication protein A. Giovanni Maga, Kristijan Ramadan, Giada A Locatelli, Igor V Shevelev, Silvio Spadari, Ulrich Hübscher The Journal of biological chemistry 2005 pols set
Structural analysis of isosteviol and related compounds as DNA polymerase and DNA topoisomerase inhibitors. Yoshiyuki Mizushina, Toshihiro Akihisa, Motohiko Ukiya, Yusuke Hamasaki, Chikako Murakami-Nakai, Isoko Kuriyama, Toshifumi Takeuchi, Fumio Sugawara, Hiromi Yoshida Life Sci 2005 pols set
HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome. Ellen M Westerhout, Marcel Ooms, Monique Vink, Atze T Das, Ben Berkhout Nucleic acids research 2005 new
Processivity clamp gp45 and ssDNA-binding-protein gp32 modulate the fidelity of bacteriophage RB69 DNA polymerase in a sequence-specific manner, sometimes enhancing and sometimes compromising accuracy. Anna Bebenek, Geraldine T Carver, Farid A Kadyrov, Grace E Kissling, John W Drake Genetics 2005 complete
Evidence of genetic variability of human immunodeficiency virus type 1 in plasma and cervicovaginal lavage in ethiopian women seeking care for sexually transmitted infections. Melaku Adal, Workenesh Ayele, Dawit Wolday, Kifle Dagne, Tsehaynesh Messele, Tesfaye Tilahun, Ben Berkhout, Shlomo Mayaan, Georgios Pollakis, Wendelien Dorigo-Zetsma AIDS Res Hum Retroviruses 2005 new
A novel pancoronavirus RT-PCR assay: frequent detection of human coronavirus NL63 in children hospitalized with respiratory tract infections in Belgium. Elien Moës, Leen Vijgen, Els Keyaerts, Kalina Zlateva, Sandra Li, Piet Maes, Krzysztof Pyrc, Ben Berkhout, Lia van der Hoek, Marc Van Ranst BMC Infect Dis 2005 new
Attenuation of DNA replication by HIV-1 reverse transcriptase near the central termination sequence. Michael E Ignatov, Anthony J Berdis, Stuart F J Le Grice, Mary D Barkley Biochemistry 2005 pols set
It's the virus, stupid--part 2. Ben Berkhout Retrovirology 2005 new
Emerging anti-HIV drugs. Erik De Clercq Expert Opin Emerg Drugs 2005 topics set
Protein promiscuity: drug resistance and native functions--HIV-1 case. Ariel Fernández, Dan S Tawfik, Ben Berkhout, Rogier W Sanders, Andrzej Kloczkowski, Taner Sen, Bob Jernigan J Biomol Struct Dyn 2005 new
[A novel colorimetric test to study the susceptibility of human cytomegalovirus DNA polymerase to foscarnet]. Alexandra Ducancelle, Sophie Alain, C Scieux, A-M Fillet, Françoise Petit, M-J Sanson-Le Pors, M-C Mazeron Pathol Biol (Paris) 2005 pols set
Reiterative template switching: the effect of single-strand homopolymeric DNA on non-template-directed nucleotide addition by DNA polymerase. Allison M Faucett, Angel L Islas Biochem Biophys Res Commun 2005 complete Angel L Islas*
Effect of DNA polymerase beta loop variants on discrimination of O6-methyldeoxyguanosine modification present in the nucleotide versus template substrate. Subarna Hamid, Kristin A Eckert Biochemistry 2005 new
Assessment of the genotoxic potential of nitric oxide-induced guanine lesions by in vitro reactions with Escherichia coli DNA polymerase I. Toshiaki Nakano, Kenjiro Asagoshi, Hiroaki Terato, Toshinori Suzuki, Hiroshi Ide Mutagenesis 2005 pols set
Optimal conditions and specific characteristics of Vent exo- DNA polymerase in ligation-mediated polymerase chain reaction protocols. François Vigneault, Régen Drouin Biochem Cell Biol 2005 pols set
RNAi Europe 2005. Ben Berkhout IDrugs 2005 new
Incorporation of reporter-labeled nucleotides by DNA polymerases. Jon P Anderson, Bernhard Angerer, Lawrence A Loeb BioTechniques 2005 partial results
Hinge residue Ile260 of DNA polymerase beta is important for enzyme activity and fidelity. Daniela Starcevic, Shibani Dalal, Joann B Sweasy Biochemistry 2005 new
A new in vivo termination function for DNA polymerase I of Escherichia coli K12. Alvin Markovitz Molecular microbiology 2005 pols set
Transcription factor YB-1 mediates DNA polymerase alpha gene expression. Abdelaziz En-Nia, Emek Yilmaz, Uwe Klinge, David H Lovett, Ioannis Stefanidis, Peter R Mertens The Journal of biological chemistry 2005 new
Localisation of human Y-family DNA polymerase kappa: relationship to PCNA foci. Tomoo Ogi, Patricia L Kannouche, Alan R Lehmann J Cell Sci 2005 new
Structure-function studies of DNA polymerase lambda. Miguel Garcia-Diaz, Katarzyna Bebenek, Guanghua Gao, Lars C Pedersen, Robert E London, Thomas A Kunkel DNA repair 2005 new
DNA polymerase beta and flap endonuclease 1 enzymatic specificities sustain DNA synthesis for long patch base excision repair. Yuan Liu, William A Beard, David D Shock, Rajendra Prasad, Esther W Hou, Samuel H Wilson The Journal of biological chemistry 2005 new
DNA polymerase kappa is specifically required for recovery from the benzo[a]pyrene-dihydrodiol epoxide (BPDE)-induced S-phase checkpoint. Xiaohui Bi, Damien M Slater, Haruo Ohmori, Cyrus Vaziri The Journal of biological chemistry 2005 new
Oxidative stress-induced retinal damage up-regulates DNA polymerase gamma and 8-oxoguanine-DNA-glycosylase in photoreceptor synaptic mitochondria. M Soledad Cortina, William C Gordon, Walter J Lukiw, Nicolas G Bazan Exp Eye Res 2005 new
Concentration and pH dependent aggregation of hydrophobic drug molecules and relevance to oral bioavailability. Yulia Volovik Frenkel, Arthur D Clark, Kalyan Das, Yuh-Hwa Wang, Paul J Lewi, Paul A J Janssen, Edward Arnold J Med Chem 2005 new
A role for polymerase eta in the cellular tolerance to cisplatin-induced damage. Mark R Albertella, Catherine M Green, Alan R Lehmann, Mark J O'Connor Cancer research 2005 new
Trf4 and Trf5 proteins of Saccharomyces cerevisiae exhibit poly(A) RNA polymerase activity but no DNA polymerase activity. Lajos Haracska, Robert E Johnson, Louise Prakash, Satya Prakash Molecular and cellular biology 2005 topics set
The multiple biological roles of the 3'-->5' exonuclease of Saccharomyces cerevisiae DNA polymerase delta require switching between the polymerase and exonuclease domains. Yong Hwan Jin, Parie Garg, Carrie M W Stith, Hanan Al-Refai, Joan F Sterling, Laura J W Murray, Thomas A Kunkel, Michael A Resnick, Peter M J Burgers, Dmitry A Gordenin Molecular and cellular biology 2005 partial results
The HIV-1 leader RNA conformational switch regulates RNA dimerization but does not regulate mRNA translation. Truus E M Abbink, Marcel Ooms, P C Joost Haasnoot, Ben Berkhout Biochemistry 2005 new
Clusters of mutations from transient hypermutability. John W Drake, Anna Bebenek, Grace E Kissling, Shyamal Peddada Proceedings of the National Academy of Sciences of the United States of America 2005 complete
Comparison of DNA polymerase activities between recombinant feline immunodeficiency and leukemia virus reverse transcriptases. Darwin J Operario, Holly M Reynolds, Baek Kim Virology 2005 partial results
Structure of a high fidelity DNA polymerase bound to a benzo[a]pyrene adduct that blocks replication. Gerald W Hsu, Xuanwei Huang, Natalia P Luneva, Nicholas E Geacintov, Lorena S Beese The Journal of biological chemistry 2005 topics set
Synthesis of novel diarylpyrimidine analogues and their antiviral activity against human immunodeficiency virus type 1. Jerome Guillemont, Elisabeth Pasquier, Patrice Palandjian, Daniel Vernier, Sandrine Gaurrand, Paul J Lewi, Jan Heeres, Marc R De Jonge, Lucien M H Koymans, Frits F D Daeyaert, Maarten H Vinkers, Edward Arnold, Kalyan Das, Rudi Pauwels, Koen Andries, Marie-Pierre P De Béthune, Eva Bettens, Kurt Hertogs, Piet Wigerinck, Philip Timmerman, Paul A J Janssen Journal of medicinal chemistry 2005 new
Up-regulation of the error-prone DNA polymerase {kappa} promotes pleiotropic genetic alterations and tumorigenesis. Clarisse Bavoux, Andréia Machado Leopoldino, Valérie Bergoglio, Jiyang O-Wang, Tomoo Ogi, Anne Bieth, Jean-Gabriel Judde, Sérgio Danilo Junho Pena, Marie-France Poupon, Thomas Helleday, Masatoshi Tagawa, Carlosrenato Machado, Jean-Sébastien Hoffmann, Christophe Cazaux Cancer research 2005 pols set
High plasma HIV load in the CRF01-AE outbreak among injecting drug users in Finland. Pia S Kivelä, Anneke Krol, Mika O Salminen, Ronald B Geskus, Jukka I Suni, Veli-Jukka Anttila, Kirsi Liitsola, Veera Zetterberg, Frank Miedema, Ben Berkhout, Roel A Coutinho, Matti A Ristola Scand J Infect Dis 2005 new
Open clamp structure in the clamp-loading complex visualized by electron microscopic image analysis. Tomoko Miyata, Hirofumi Suzuki, Takuji Oyama, Kouta Mayanagi, Yoshizumi Ishino, Kosuke Morikawa Proceedings of the National Academy of Sciences of the United States of America 2005 new
Design, synthesis, and SAR of a novel pyrazinone series with non-nucleoside HIV-1 reverse transcriptase inhibitory activity. Jan Heeres, Marc R De Jonge, Lucien M H Koymans, Frits F D Daeyaert, Maarten H Vinkers, Koen J A Van Aken, Edward Arnold, Kalyan Das, Amuri Kilonda, Georges J Hoornaert, Frans Compernolle, Marek Cegla, Rasha A Azzam, Koen Andries, Marie-Pierre P De Béthune, Hilde Azijn, Rudi Pauwels, Paul J Lewi, Paul A J Janssen Journal of medicinal chemistry 2005 pols set
Saccharomyces cerevisiae DNA polymerase delta: high fidelity for base substitutions but lower fidelity for single- and multi-base deletions. John M Fortune, Youri I Pavlov, Carrie M Welch, Erik Johansson, Peter M J Burgers, Thomas A Kunkel The Journal of biological chemistry 2005 pols set
DNA polymerases that propagate the eukaryotic DNA replication fork. Parie Garg, Peter M J Burgers Crit Rev Biochem Mol Biol 2005 new
Evidence for a Watson-Crick hydrogen bonding requirement in DNA synthesis by human DNA polymerase kappa. William T Wolfle, M Todd Washington, Eric T Kool, Thomas E Spratt, Sandra A Helquist, Louise Prakash, Satya Prakash Molecular and cellular biology 2005 topics set
The 3'-azido group is not the primary determinant of 3'-azido-3'-deoxythymidine (AZT) responsible for the excision phenotype of AZT-resistant HIV-1. Nicolas Sluis-Cremer, Dominique Arion, Urvi Parikh, Dianna Koontz, Raymond F Schinazi, John W Mellors, Michael A. Parniak The Journal of biological chemistry 2005 topics set
Effective form of sulfoquinovosyldiacyglycerol (SQDG) vesicles for DNA polymerase inhibition. Kenjiro Matsumoto, Hideki Sakai, Ryo Takeuchi, Koji Tsuchiya, Keisuke Ohta, Fumio Sugawara, Masahiko Abe, Kengo Sakaguchi Colloids Surf B Biointerfaces 2005 new
The screening of expression and purification conditions for replicative DNA polymerase associated B-subunits, assignment of the exonuclease activity to the C-terminus of archaeal pol D DP1 subunit. Maarit Jokela, Mari Raki, Kaisa Heikkinen, Katri Sepponen, Anitta Eskelinen, Juhani E Syväoja Protein Expr Purif 2005 new
Correction of X-ray intensities from single crystals containing lattice-translocation defects. Jianhong Wang, Satwik Kamtekar, Andrea J Berman, Thomas A Steitz Acta Crystallogr D Biol Crystallogr 2005 topics set
Structure and mechanism of DNA polymerases. Paul J Rothwell, Gabriel Waksman Adv Protein Chem 2005 topics set
A single domain in human DNA polymerase iota mediates interaction with PCNA: implications for translesion DNA synthesis. Lajos Haracska, Narottam Acharya, Ildiko Unk, Robert E Johnson, Jerard Hurwitz, Louise Prakash, Satya Prakash Molecular and cellular biology 2005 pols set
DNA adduct bypass polymerization by Sulfolobus solfataricus DNA polymerase Dpo4: analysis and crystal structures of multiple base pair substitution and frameshift products with the adduct 1,N2-ethenoguanine. Hong Zang, Angela K Goodenough, Jeong-Yun Choi, Adriana Irimia, Lioudmila V Loukachevitch, Ivan D Kozekov, Karen C Angel, Carmelo J Rizzo, Martin Egli, F Peter Guengerich The Journal of biological chemistry 2005 topics set
Characterization of SpPol4, a unique X-family DNA polymerase in Schizosaccharomyces pombe. Sergio González-Barrera, Arancha Sánchez, José F Ruiz, Raquel Juárez, Angel J Picher, Gloria Terrados, Paula Andrade, Luis Blanco Nucleic acids research 2005 topics set
Interaction between the T4 helicase loading protein (gp59) and the DNA polymerase (gp43): unlocking of the gp59-gp43-DNA complex to initiate assembly of a fully functional replisome. Jun Xi, Zhiquan Zhang, Zhihao Zhuang, Jingsong Yang, Michelle M Spiering, Gordon G Hammes, Stephen J Benkovic Biochemistry 2005 topics set
Photoregulation of DNA polymerase I (Klenow) with caged fluorescent oligodeoxynucleotides. XinJing Tang, Julia L Richards, Adam E Peritz, Ivan J Dmochowski Bioorganic & medicinal chemistry letters 2005 complete Ivan J Dmochowski*
Long-patch base excision DNA repair of 2-deoxyribonolactone prevents the formation of DNA-protein cross-links with DNA polymerase beta. Jung-Suk Sung, Michael S DeMott, Bruce Demple The Journal of biological chemistry 2005 new
[Isolation and characterization of the thermostable DNA polymerase of the hyperthermophilic archaeum Thermococcus litoralis Sh1AM] Prikladnaia biokhimiia i mikrobiologiia 2005 topics set
Fluorous base-pairing effects in a DNA polymerase active site. Jacob S Lai, Eric T Kool Chemistry 2005 new
Interaction between the T4 helicase-loading protein (gp59) and the DNA polymerase (gp43): a locking mechanism to delay replication during replisome assembly. Jun Xi, Zhihao Zhuang, Zhiquan Zhang, Tzvia Selzer, Michelle M Spiering, Gordon G Hammes, Stephen J Benkovic Biochemistry 2005 new
Application of Phi29 DNA polymerase mediated whole genome amplification on single spores of arbuscular mycorrhizal (AM) fungi. Vijay Gadkar, Matthias C Rillig FEMS Microbiol Lett 2005 pols set
Mechanism of efficient and accurate nucleotide incorporation opposite 7,8-dihydro-8-oxoguanine by Saccharomyces cerevisiae DNA polymerase eta. Karissa D Carlson, M Todd Washington Molecular and cellular biology 2005 complete M Todd Washington*
In search of a novel anti-HIV drug: multidisciplinary coordination in the discovery of 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile (R278474, rilpivirine). Paul A J Janssen, Paul J Lewi, Edward Arnold, Frits F D Daeyaert, Marc R De Jonge, Jan Heeres, Luc Koymans, Maarten H Vinkers, Jérôme Guillemont, Elisabeth Pasquier, Michael Kukla, Don Ludovici, Koen Andries, Marie-Pierre P De Béthune, Rudi Pauwels, Kalyan Das, Arthur D Clark, Yulia Volovik Frenkel, Stephen H Hughes, Bart Medaer, Fons De Knaep, Hilde Bohets, Fred De Clerck, Ann Lampo, Peter Williams, Paul Stoffels J Med Chem 2005 new
Synthesis of universal unmethylated control DNA by nested whole genome amplification with phi29 DNA polymerase. Naoyuki Umetani, Michiel F G de Maat, Takuji Mori, Hiroya Takeuchi, Dave S B Hoon Biochem Biophys Res Commun 2005 pols set
DNA polymerase clamp loaders and DNA recognition. Gregory D Bowman, Eric R Goedken, Steven L Kazmirski, Mike E O'Donnell, John Kuriyan FEBS letters 2005 new
Mechanism for N-acetyl-2-aminofluorene-induced frameshift mutagenesis by Escherichia coli DNA polymerase I (Klenow fragment). JP Gill, Louis J Romano Biochemistry 2005 pols set
DNA polymerase V and RecA protein, a minimal mutasome. Katharina Schlacher, Kris Leslie, Claire Wyman, Roger Woodgate, Michael M Cox, Myron F Goodman Molecular cell 2005 new
Identification of amino acid residues in the human immunodeficiency virus type-1 reverse transcriptase tryptophan-repeat motif that are required for subunit interaction using infectious virions. Alok Mulky, Stefan G Sarafianos, Yujiang Jia, Edward Arnold, John C Kappes Journal of molecular biology 2005 new
Nucleotide-induced DNA polymerase active site motions accommodating a mutagenic DNA intermediate. Vinod K Batra, William A Beard, David D Shock, Lars C Pedersen, Samuel H Wilson Structure (London, England : 1993) 2005 topics set
Structural mechanism for coordination of proofreading and polymerase activities in archaeal DNA polymerases. Toshihiro Kuroita, Hiroyoshi Matsumura, Naohiko Yokota, Masao Kitabayashi, Hiroshi Hashimoto, Tsuyoshi Inoue, Tadayuki Imanaka, Yasushi Kai Journal of molecular biology 2005 topics set
How are specialized (low-fidelity) eukaryotic polymerases selected and switched with high-fidelity polymerases during translesion DNA synthesis? Paula L Fischhaber, Errol C Friedberg DNA repair 2005 topics set
Deoxythreosyl phosphonate nucleosides as selective anti-HIV agents. Tongfei Wu, Matheus Froeyen, Veerle Kempeneers, Christophe Pannecouque, Jing Wang, Roger Busson, Erik De Clercq, Piet Herdewijn Journal of the American Chemical Society 2005 pols set
A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining. Stephanie A Nick McElhinny, Jody M Havener, Miguel Garcia-Diaz, Raquel Juárez, Katarzyna Bebenek, Barbara L Kee, Luis Blanco, Thomas A Kunkel, Dale A Ramsden Molecular cell 2005 new
Consequences of mutations in human DNA polymerase gamma. Matthew J Longley, Maria A Graziewicz, Rachelle J Bienstock, William C Copeland Gene 2005 pols set
(+)-Myristinins A and D from Knema elegans, which inhibit DNA polymerase beta and cleave DNA. Jing-Zhen Deng, Shelley R Starck, Shisheng Li, Sidney M Hecht J Nat Prod 2005 new
Bumps in the road: how replicative DNA polymerases see DNA damage. Matthew Hogg, Susan S Wallace, Sylvie Doublié Current opinion in structural biology 2005 complete Sylvie Doublié*
Frequent mutation related with overexpression of DNA polymerase beta in primary tumors and precancerous lesions of human stomach. Xiao-Hui Tan, Min Zhao, Kai-Feng Pan, Ying Dong, Bin Dong, Gui-Jian Feng, Guang Jia, You-Yong Lu Cancer Lett 2005 new
Enhanced activity of DNA polymerase iota in mouse brain cells is associated with aggressiveness. Leonid V Gening, A A Kamensky, N G Levitskaya, A N Petrochenkov, I I Poletaeva, Vyacheslav Z Taran